Explainable Generative Deep Learning for plant transcription factor binding sites discovery

Genome-Scale Analysis in the Tea Genome

PTF-Vāc was applied to the entire tea genome to identify BES1 transcription factor binding sites, leveraging AlphaFold2-generated protein structure. This analysis of 2 kb upstream promoter regions across all tea genes identified 1,878 potential BES1 target genes, demonstrating PTF-Vāc's capability for comprehensive genome-wide regulatory network identification.