| DNA helicase activity |
GO:0003678 |
1282 |
| AT DNA binding |
GO:0003680 |
770 |
| Bent DNA binding |
GO:0003681 |
8 |
| Chromatin binding |
GO:0003682 |
5914 |
| Damaged DNA binding |
GO:0003684 |
4019 |
| DNA replication origin binding |
GO:0003688 |
7 |
| DNA clamp loader activity |
GO:0003689 |
961 |
| Double-stranded DNA binding |
GO:0003690 |
2815 |
| Double-stranded telomeric DNA binding |
GO:0003691 |
1295 |
| Left-handed Z-DNA binding |
GO:0003692 |
619 |
| Satellite DNA binding |
GO:0003696 |
125 |
| Single-stranded DNA binding |
GO:0003697 |
3815 |
| Sequence-specific DNA binding transcription factor activity |
GO:0003700 |
7663 |
| RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
GO:0003705 |
1669 |
| Steroid hormone receptor activity |
GO:0003707 |
3114 |
| Retinoic acid receptor activity |
GO:0003708 |
67 |
| Transcription cofactor activity |
GO:0003712 |
3781 |
| Transcription coactivator activity |
GO:0003713 |
5261 |
| Transcription corepressor activity |
GO:0003714 |
5029 |
| Telomerase activity |
GO:0003720 |
1190 |
| RNA binding |
GO:0003723 |
6478 |
| RNA helicase activity |
GO:0003724 |
604 |
| Double-stranded RNA binding |
GO:0003725 |
2567 |
| Double-stranded RNA adenosine deaminase activity |
GO:0003726 |
1106 |
| Single-stranded RNA binding |
GO:0003727 |
2515 |
| MRNA binding |
GO:0003729 |
3692 |
| MRNA 3'-UTR binding |
GO:0003730 |
670 |
| Structural constituent of ribosome |
GO:0003735 |
4488 |
| Translation initiation factor activity |
GO:0003743 |
3422 |
| Translation elongation factor activity |
GO:0003746 |
1354 |
| Translation release factor activity |
GO:0003747 |
1097 |
| Peptidyl-prolyl cis-trans isomerase activity |
GO:0003755 |
2742 |
| Protein disulfide isomerase activity |
GO:0003756 |
437 |
| Motor activity |
GO:0003774 |
3682 |
| Microtubule motor activity |
GO:0003777 |
3832 |
| Actin binding |
GO:0003779 |
6606 |
| Actin monomer binding |
GO:0003785 |
1525 |
| Lysozyme activity |
GO:0003796 |
886 |
| Protein-glutamine gamma-glutamyltransferase activity |
GO:0003810 |
22 |
| Antigen binding |
GO:0003823 |
2149 |
| Catalytic activity |
GO:0003824 |
5143 |
| Alpha-ketoacid dehydrogenase activity |
GO:0003826 |
2 |
| Alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity |
GO:0003827 |
5 |
| Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity |
GO:0003828 |
1025 |
| Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity |
GO:0003829 |
360 |
| Beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity |
GO:0003830 |
5 |
| Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity |
GO:0003831 |
24 |
| Beta-galactoside alpha-2,6-sialyltransferase activity |
GO:0003835 |
731 |
| Beta-galactoside (CMP) alpha-2,3-sialyltransferase activity |
GO:0003836 |
379 |
| Gamma-glutamyltransferase activity |
GO:0003840 |
746 |
| 1-acylglycerol-3-phosphate O-acyltransferase activity |
GO:0003841 |
1247 |
| 1-pyrroline-5-carboxylate dehydrogenase activity |
GO:0003842 |
3 |
| 1,4-alpha-glucan branching enzyme activity |
GO:0003844 |
3 |
| 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity |
GO:0003845 |
1 |
| 2-acylglycerol O-acyltransferase activity |
GO:0003846 |
282 |
| 1-alkyl-2-acetylglycerophosphocholine esterase activity |
GO:0003847 |
1568 |
| 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity |
GO:0003851 |
44 |
| 3-beta-hydroxy-delta5-steroid dehydrogenase activity |
GO:0003854 |
343 |
| 3-hydroxyacyl-CoA dehydrogenase activity |
GO:0003857 |
294 |
| 3-hydroxybutyrate dehydrogenase activity |
GO:0003858 |
744 |
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity |
GO:0003863 |
2 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase activity |
GO:0003865 |
4 |
| 4-aminobutyrate transaminase activity |
GO:0003867 |
7 |
| 4-hydroxyphenylpyruvate dioxygenase activity |
GO:0003868 |
14 |
| 5-aminolevulinate synthase activity |
GO:0003870 |
2 |
| 6-phosphofructokinase activity |
GO:0003872 |
5 |
| 6-phosphofructo-2-kinase activity |
GO:0003873 |
145 |
| 6-pyruvoyltetrahydropterin synthase activity |
GO:0003874 |
1 |
| ADP-ribosylarginine hydrolase activity |
GO:0003875 |
7 |
| AMP deaminase activity |
GO:0003876 |
14 |
| ATP citrate synthase activity |
GO:0003878 |
5 |
| Protein C-terminal carboxyl O-methyltransferase activity |
GO:0003880 |
1629 |
| CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity |
GO:0003881 |
4 |
| CTP synthase activity |
GO:0003883 |
7 |
| D-amino-acid oxidase activity |
GO:0003884 |
1 |
| DNA (cytosine-5-)-methyltransferase activity |
GO:0003886 |
546 |
| DNA-directed DNA polymerase activity |
GO:0003887 |
3215 |
| DNA primase activity |
GO:0003896 |
207 |
| DNA-directed RNA polymerase activity |
GO:0003899 |
2932 |
| Deoxyribodipyrimidine photo-lyase activity |
GO:0003904 |
10 |
| DNA-(apurinic or apyrimidinic site) lyase activity |
GO:0003906 |
903 |
| Methylated-DNA-[protein]-cysteine S-methyltransferase activity |
GO:0003908 |
1 |
| DNA ligase activity |
GO:0003909 |
7 |
| DNA ligase (ATP) activity |
GO:0003910 |
7 |
| DNA nucleotidylexotransferase activity |
GO:0003912 |
1 |
| DNA (6-4) photolyase activity |
GO:0003914 |
10 |
| DNA topoisomerase activity |
GO:0003916 |
5 |
| DNA topoisomerase type I activity |
GO:0003917 |
534 |
| DNA topoisomerase (ATP-hydrolyzing) activity |
GO:0003918 |
9 |
| FMN adenylyltransferase activity |
GO:0003919 |
348 |
| GMP reductase activity |
GO:0003920 |
8 |
| GPI-anchor transamidase activity |
GO:0003923 |
24 |
| GTPase activity |
GO:0003924 |
6076 |
| GTP cyclohydrolase I activity |
GO:0003934 |
2 |
| IMP cyclohydrolase activity |
GO:0003937 |
2 |
| IMP dehydrogenase activity |
GO:0003938 |
5 |
| L-iditol 2-dehydrogenase activity |
GO:0003939 |
2 |
| L-iduronidase activity |
GO:0003940 |
2 |
| L-serine ammonia-lyase activity |
GO:0003941 |
361 |
| N-acetylgalactosamine-4-sulfatase activity |
GO:0003943 |
891 |
| N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity |
GO:0003944 |
4 |
| N-acetyllactosamine synthase activity |
GO:0003945 |
11 |
| N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
GO:0003948 |
71 |
| NAD+ ADP-ribosyltransferase activity |
GO:0003950 |
1465 |
| NAD+ kinase activity |
GO:0003951 |
2163 |
| NAD+ nucleosidase activity |
GO:0003953 |
62 |
| NADH dehydrogenase activity |
GO:0003954 |
14 |
| NAD(P)H dehydrogenase (quinone) activity |
GO:0003955 |
685 |
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity |
GO:0003956 |
4 |
| NAD(P)+ transhydrogenase (B-specific) activity |
GO:0003957 |
5 |
| NADPH-hemoprotein reductase activity |
GO:0003958 |
1503 |
| NADPH:quinone reductase activity |
GO:0003960 |
13 |
| RNA-3'-phosphate cyclase activity |
GO:0003963 |
1078 |
| RNA-directed RNA polymerase activity |
GO:0003968 |
3 |
| (S)-2-hydroxy-acid oxidase activity |
GO:0003973 |
3 |
| UDP-N-acetylglucosamine 4-epimerase activity |
GO:0003974 |
3 |
| UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity |
GO:0003975 |
1 |
| UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity |
GO:0003976 |
455 |
| UDP-N-acetylglucosamine diphosphorylase activity |
GO:0003977 |
2 |
| UDP-glucose 4-epimerase activity |
GO:0003978 |
3 |
| UDP-glucose 6-dehydrogenase activity |
GO:0003979 |
773 |
| UTP:glucose-1-phosphate uridylyltransferase activity |
GO:0003983 |
2 |
| Acetyl-CoA C-acetyltransferase activity |
GO:0003985 |
5 |
| Acetyl-CoA hydrolase activity |
GO:0003986 |
160 |
| Acetate-CoA ligase activity |
GO:0003987 |
8 |
| Acetyl-CoA C-acyltransferase activity |
GO:0003988 |
5 |
| Acetyl-CoA carboxylase activity |
GO:0003989 |
1051 |
| Acetylcholinesterase activity |
GO:0003990 |
7 |
| Acid phosphatase activity |
GO:0003993 |
507 |
| Acyl-CoA dehydrogenase activity |
GO:0003995 |
2572 |
| Acyl-CoA ligase activity |
GO:0003996 |
1 |
| Acyl-CoA oxidase activity |
GO:0003997 |
1601 |
| Adenosine deaminase activity |
GO:0004000 |
1312 |
| Adenosine kinase activity |
GO:0004001 |
2 |
| ATP-dependent DNA helicase activity |
GO:0004003 |
2037 |
| ATP-dependent RNA helicase activity |
GO:0004004 |
763 |
| Copper-exporting ATPase activity |
GO:0004008 |
440 |
| Phospholipid-translocating ATPase activity |
GO:0004012 |
1277 |
| Adenosylhomocysteinase activity |
GO:0004013 |
283 |
| Adenylate cyclase activity |
GO:0004016 |
1003 |
| Adenylate kinase activity |
GO:0004017 |
826 |
| N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity |
GO:0004018 |
2 |
| Adenylosuccinate synthase activity |
GO:0004019 |
1 |
| Adenylylsulfate kinase activity |
GO:0004020 |
9 |
| L-alanine:2-oxoglutarate aminotransferase activity |
GO:0004021 |
2 |
| Alcohol dehydrogenase (NAD) activity |
GO:0004022 |
13 |
| Alcohol dehydrogenase activity, zinc-dependent |
GO:0004024 |
15 |
| Alcohol sulfotransferase activity |
GO:0004027 |
14 |
| 3-chloroallyl aldehyde dehydrogenase activity |
GO:0004028 |
817 |
| Aldehyde dehydrogenase (NAD) activity |
GO:0004029 |
3102 |
| Aldehyde dehydrogenase [NAD(P)+] activity |
GO:0004030 |
817 |
| Aldehyde oxidase activity |
GO:0004031 |
10 |
| Alditol:NADP+ 1-oxidoreductase activity |
GO:0004032 |
432 |
| Aldo-keto reductase (NADP) activity |
GO:0004033 |
454 |
| Aldose 1-epimerase activity |
GO:0004034 |
749 |
| Alkaline phosphatase activity |
GO:0004035 |
18 |
| Allantoicase activity |
GO:0004037 |
1 |
| Amidase activity |
GO:0004040 |
2 |
| Acetyl-CoA:L-glutamate N-acetyltransferase activity |
GO:0004042 |
3 |
| L-aminoadipate-semialdehyde dehydrogenase activity |
GO:0004043 |
519 |
| Amidophosphoribosyltransferase activity |
GO:0004044 |
7 |
| Aminoacylase activity |
GO:0004046 |
5 |
| Aminomethyltransferase activity |
GO:0004047 |
1609 |
| Arachidonate 5-lipoxygenase activity |
GO:0004051 |
2 |
| Arachidonate 12-lipoxygenase activity |
GO:0004052 |
194 |
| Arginase activity |
GO:0004053 |
1 |
| Argininosuccinate synthase activity |
GO:0004055 |
2 |
| Argininosuccinate lyase activity |
GO:0004056 |
139 |
| Arginyltransferase activity |
GO:0004057 |
6 |
| Aromatic-L-amino-acid decarboxylase activity |
GO:0004058 |
1 |
| Aralkylamine N-acetyltransferase activity |
GO:0004059 |
118 |
| Arylamine N-acetyltransferase activity |
GO:0004060 |
123 |
| Arylformamidase activity |
GO:0004061 |
713 |
| Aryl sulfotransferase activity |
GO:0004062 |
179 |
| Aryldialkylphosphatase activity |
GO:0004063 |
1 |
| Arylesterase activity |
GO:0004064 |
3 |
| Arylsulfatase activity |
GO:0004065 |
2257 |
| Asparaginase activity |
GO:0004067 |
72 |
| Aspartate 1-decarboxylase activity |
GO:0004068 |
15 |
| L-aspartate:2-oxoglutarate aminotransferase activity |
GO:0004069 |
5 |
| Aspartate carbamoyltransferase activity |
GO:0004070 |
6 |
| Biliverdin reductase activity |
GO:0004074 |
1 |
| Biotin carboxylase activity |
GO:0004075 |
1055 |
| Biotin-[acetyl-CoA-carboxylase] ligase activity |
GO:0004077 |
523 |
| Biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity |
GO:0004078 |
523 |
| Biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity |
GO:0004079 |
523 |
| Biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity |
GO:0004080 |
523 |
| Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity |
GO:0004081 |
4 |
| Bisphosphoglycerate mutase activity |
GO:0004082 |
1 |
| Bisphosphoglycerate 2-phosphatase activity |
GO:0004083 |
1 |
| Branched-chain-amino-acid transaminase activity |
GO:0004084 |
13 |
| Butyryl-CoA dehydrogenase activity |
GO:0004085 |
3 |
| Carbamoyl-phosphate synthase (ammonia) activity |
GO:0004087 |
135 |
| Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity |
GO:0004088 |
135 |
| Carbonate dehydratase activity |
GO:0004089 |
860 |
| Carbonyl reductase (NADPH) activity |
GO:0004090 |
199 |
| Carnitine O-acetyltransferase activity |
GO:0004092 |
4 |
| Carnitine O-palmitoyltransferase activity |
GO:0004095 |
1832 |
| Catalase activity |
GO:0004096 |
3 |
| Cerebroside-sulfatase activity |
GO:0004098 |
1286 |
| Choline O-acetyltransferase activity |
GO:0004102 |
4 |
| Choline kinase activity |
GO:0004103 |
1 |
| Cholinesterase activity |
GO:0004104 |
8 |
| Choline-phosphate cytidylyltransferase activity |
GO:0004105 |
565 |
| Coproporphyrinogen oxidase activity |
GO:0004109 |
11 |
| Creatine kinase activity |
GO:0004111 |
4 |
| Cyclic-nucleotide phosphodiesterase activity |
GO:0004112 |
1187 |
| 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity |
GO:0004113 |
152 |
| 3',5'-cyclic-nucleotide phosphodiesterase activity |
GO:0004114 |
3301 |
| 3',5'-cyclic-AMP phosphodiesterase activity |
GO:0004115 |
2461 |
| Calmodulin-dependent cyclic-nucleotide phosphodiesterase activity |
GO:0004117 |
24 |
| CGMP-stimulated cyclic-nucleotide phosphodiesterase activity |
GO:0004118 |
1193 |
| CGMP-inhibited cyclic-nucleotide phosphodiesterase activity |
GO:0004119 |
26 |
| Cystathionine beta-synthase activity |
GO:0004122 |
2 |
| Cystathionine gamma-lyase activity |
GO:0004123 |
301 |
| Cytidine deaminase activity |
GO:0004126 |
1161 |
| Cytochrome-b5 reductase activity |
GO:0004128 |
1763 |
| Cytochrome-c oxidase activity |
GO:0004129 |
1163 |
| Glycogen debranching enzyme activity |
GO:0004133 |
83 |
| 4-alpha-glucanotransferase activity |
GO:0004134 |
83 |
| Amylo-alpha-1,6-glucosidase activity |
GO:0004135 |
83 |
| Deoxycytidine kinase activity |
GO:0004137 |
106 |
| Deoxyribose-phosphate aldolase activity |
GO:0004139 |
1 |
| Dephospho-CoA kinase activity |
GO:0004140 |
5 |
| Diacylglycerol cholinephosphotransferase activity |
GO:0004142 |
6 |
| Diacylglycerol kinase activity |
GO:0004143 |
1507 |
| Diacylglycerol O-acyltransferase activity |
GO:0004144 |
284 |
| Diamine N-acetyltransferase activity |
GO:0004145 |
1 |
| Dihydrofolate reductase activity |
GO:0004146 |
1208 |
| Dihydrolipoyl dehydrogenase activity |
GO:0004148 |
6 |
| Dihydrolipoyllysine-residue succinyltransferase activity |
GO:0004149 |
2 |
| Dihydroorotase activity |
GO:0004151 |
6 |
| Dihydroorotate dehydrogenase activity |
GO:0004152 |
19 |
| 6,7-dihydropteridine reductase activity |
GO:0004155 |
2 |
| Dihydropyrimidinase activity |
GO:0004157 |
6 |
| Dimethylallyltranstransferase activity |
GO:0004161 |
750 |
| Diphosphomevalonate decarboxylase activity |
GO:0004163 |
1 |
| Diphthine synthase activity |
GO:0004164 |
4 |
| Dodecenoyl-CoA delta-isomerase activity |
GO:0004165 |
284 |
| Dolichol kinase activity |
GO:0004168 |
2 |
| Dolichyl-phosphate-mannose-protein mannosyltransferase activity |
GO:0004169 |
3 |
| DUTP diphosphatase activity |
GO:0004170 |
3 |
| Electron-transferring-flavoprotein dehydrogenase activity |
GO:0004174 |
476 |
| Endopeptidase activity |
GO:0004175 |
832 |
| ATP-dependent peptidase activity |
GO:0004176 |
1202 |
| Aminopeptidase activity |
GO:0004177 |
3425 |
| Carboxypeptidase activity |
GO:0004180 |
2051 |
| Metallocarboxypeptidase activity |
GO:0004181 |
2300 |
| Serine-type carboxypeptidase activity |
GO:0004185 |
6 |
| Aspartic-type endopeptidase activity |
GO:0004190 |
1831 |
| Cysteine-type endopeptidase activity |
GO:0004197 |
4962 |
| Calcium-dependent cysteine-type endopeptidase activity |
GO:0004198 |
382 |
| Ubiquitin thiolesterase activity |
GO:0004221 |
4219 |
| Metalloendopeptidase activity |
GO:0004222 |
3409 |
| Serine-type endopeptidase activity |
GO:0004252 |
3227 |
| Threonine-type endopeptidase activity |
GO:0004298 |
1612 |
| Enoyl-CoA hydratase activity |
GO:0004300 |
292 |
| Epoxide hydrolase activity |
GO:0004301 |
147 |
| Estradiol 17-beta-dehydrogenase activity |
GO:0004303 |
549 |
| Estrone sulfotransferase activity |
GO:0004304 |
130 |
| Ethanolamine kinase activity |
GO:0004305 |
6 |
| Ethanolamine-phosphate cytidylyltransferase activity |
GO:0004306 |
1 |
| Ethanolaminephosphotransferase activity |
GO:0004307 |
470 |
| Exo-alpha-sialidase activity |
GO:0004308 |
3 |
| Farnesyl-diphosphate farnesyltransferase activity |
GO:0004310 |
10 |
| Farnesyltranstransferase activity |
GO:0004311 |
750 |
| Oleoyl-[acyl-carrier-protein] hydrolase activity |
GO:0004320 |
675 |
| Ferroxidase activity |
GO:0004322 |
1946 |
| Ferredoxin-NADP+ reductase activity |
GO:0004324 |
2 |
| Ferrochelatase activity |
GO:0004325 |
1061 |
| Tetrahydrofolylpolyglutamate synthase activity |
GO:0004326 |
2 |
| Formate-tetrahydrofolate ligase activity |
GO:0004329 |
114 |
| Fructose-2,6-bisphosphate 2-phosphatase activity |
GO:0004331 |
145 |
| Fructose-bisphosphate aldolase activity |
GO:0004332 |
7 |
| Fumarate hydratase activity |
GO:0004333 |
2 |
| Fumarylacetoacetase activity |
GO:0004334 |
1 |
| Galactokinase activity |
GO:0004335 |
215 |
| Galactosylceramidase activity |
GO:0004336 |
8 |
| Geranyltranstransferase activity |
GO:0004337 |
750 |
| Glucokinase activity |
GO:0004340 |
274 |
| Glucosamine-6-phosphate deaminase activity |
GO:0004342 |
3 |
| Glucosamine 6-phosphate N-acetyltransferase activity |
GO:0004343 |
894 |
| Glucose-6-phosphate dehydrogenase activity |
GO:0004345 |
6 |
| Glucose-6-phosphatase activity |
GO:0004346 |
816 |
| Glucose-6-phosphate isomerase activity |
GO:0004347 |
1415 |
| Glucosylceramidase activity |
GO:0004348 |
3 |
| Glutamate 5-kinase activity |
GO:0004349 |
5 |
| Glutamate-5-semialdehyde dehydrogenase activity |
GO:0004350 |
5 |
| Glutamate decarboxylase activity |
GO:0004351 |
14 |
| Glutamate dehydrogenase (NAD+) activity |
GO:0004352 |
4 |
| Glutamate dehydrogenase [NAD(P)+] activity |
GO:0004353 |
4 |
| Glutamate-ammonia ligase activity |
GO:0004356 |
779 |
| Glutamate-cysteine ligase activity |
GO:0004357 |
1043 |
| Glutaminase activity |
GO:0004359 |
14 |
| Glutamine-fructose-6-phosphate transaminase (isomerizing) activity |
GO:0004360 |
1346 |
| Glutaryl-CoA dehydrogenase activity |
GO:0004361 |
1 |
| Glutathione-disulfide reductase activity |
GO:0004362 |
457 |
| Glutathione synthase activity |
GO:0004363 |
2 |
| Glutathione transferase activity |
GO:0004364 |
1139 |
| Glycerol-3-phosphate O-acyltransferase activity |
GO:0004366 |
542 |
| Glycerol-3-phosphate dehydrogenase [NAD+] activity |
GO:0004367 |
6 |
| Glycerol-3-phosphate dehydrogenase activity |
GO:0004368 |
9 |
| Glycerol kinase activity |
GO:0004370 |
2355 |
| Glycine hydroxymethyltransferase activity |
GO:0004372 |
9 |
| Glycogen (starch) synthase activity |
GO:0004373 |
4 |
| Glycine dehydrogenase (decarboxylating) activity |
GO:0004375 |
3 |
| GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity |
GO:0004378 |
3 |
| Glycylpeptide N-tetradecanoyltransferase activity |
GO:0004379 |
1458 |
| Guanosine-diphosphatase activity |
GO:0004382 |
3 |
| Guanylate cyclase activity |
GO:0004383 |
86 |
| Guanylate kinase activity |
GO:0004385 |
48 |
| Helicase activity |
GO:0004386 |
3384 |
| Heme oxygenase (decyclizing) activity |
GO:0004392 |
694 |
| Hexaprenyldihydroxybenzoate methyltransferase activity |
GO:0004395 |
4 |
| Hexokinase activity |
GO:0004396 |
269 |
| Histidine ammonia-lyase activity |
GO:0004397 |
4 |
| Histidine decarboxylase activity |
GO:0004398 |
2 |
| Histone acetyltransferase activity |
GO:0004402 |
2606 |
| Histone deacetylase activity |
GO:0004407 |
1205 |
| Holocytochrome-c synthase activity |
GO:0004408 |
3 |
| Homogentisate 1,2-dioxygenase activity |
GO:0004411 |
1 |
| Hyalurononglucosaminidase activity |
GO:0004415 |
468 |
| Hydroxyacylglutathione hydrolase activity |
GO:0004416 |
9 |
| Hydroxymethylbilane synthase activity |
GO:0004418 |
7 |
| Hydroxymethylglutaryl-CoA lyase activity |
GO:0004419 |
5 |
| Hydroxymethylglutaryl-CoA reductase (NADPH) activity |
GO:0004420 |
4 |
| Hydroxymethylglutaryl-CoA synthase activity |
GO:0004421 |
7 |
| Iduronate-2-sulfatase activity |
GO:0004423 |
1038 |
| Inorganic diphosphatase activity |
GO:0004427 |
527 |
| 1-phosphatidylinositol 4-kinase activity |
GO:0004430 |
13 |
| Phosphatidylinositol phospholipase C activity |
GO:0004435 |
2080 |
| Phosphatidylinositol-3-phosphatase activity |
GO:0004438 |
304 |
| Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity |
GO:0004439 |
975 |
| Inositol-1,4-bisphosphate 1-phosphatase activity |
GO:0004441 |
2 |
| Inositol-polyphosphate 5-phosphatase activity |
GO:0004445 |
22 |
| Iodide peroxidase activity |
GO:0004447 |
759 |
| Isocitrate dehydrogenase (NAD+) activity |
GO:0004449 |
4 |
| Isopentenyl-diphosphate delta-isomerase activity |
GO:0004452 |
4 |
| L-lactate dehydrogenase activity |
GO:0004459 |
186 |
| Lactose synthase activity |
GO:0004461 |
7 |
| Lactoylglutathione lyase activity |
GO:0004462 |
2 |
| Leukotriene-A4 hydrolase activity |
GO:0004463 |
146 |
| Leukotriene-C4 synthase activity |
GO:0004464 |
1 |
| Lipoprotein lipase activity |
GO:0004465 |
11 |
| Long-chain-acyl-CoA dehydrogenase activity |
GO:0004466 |
5 |
| Long-chain fatty acid-CoA ligase activity |
GO:0004467 |
1023 |
| Lysine N-acetyltransferase activity |
GO:0004468 |
131 |
| Malic enzyme activity |
GO:0004470 |
7 |
| Malate dehydrogenase (decarboxylating) activity |
GO:0004471 |
933 |
| Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity |
GO:0004473 |
7 |
| Mannose-6-phosphate isomerase activity |
GO:0004476 |
568 |
| Methenyltetrahydrofolate cyclohydrolase activity |
GO:0004477 |
114 |
| Methionine adenosyltransferase activity |
GO:0004478 |
4 |
| Methionyl-tRNA formyltransferase activity |
GO:0004479 |
1421 |
| MRNA (guanine-N7-)-methyltransferase activity |
GO:0004482 |
6 |
| Methylcrotonoyl-CoA carboxylase activity |
GO:0004485 |
342 |
| Methylenetetrahydrofolate dehydrogenase (NAD+) activity |
GO:0004487 |
2 |
| Methylenetetrahydrofolate dehydrogenase (NADP+) activity |
GO:0004488 |
114 |
| Methylglutaconyl-CoA hydratase activity |
GO:0004490 |
1 |
| Methylmalonate-semialdehyde dehydrogenase (acylating) activity |
GO:0004491 |
1616 |
| Methylmalonyl-CoA decarboxylase activity |
GO:0004492 |
1 |
| Methylmalonyl-CoA mutase activity |
GO:0004494 |
4 |
| Mevalonate kinase activity |
GO:0004496 |
1 |
| Monooxygenase activity |
GO:0004497 |
3525 |
| Calcidiol 1-monooxygenase activity |
GO:0004498 |
3 |
| N,N-dimethylaniline monooxygenase activity |
GO:0004499 |
9 |
| Dopamine beta-monooxygenase activity |
GO:0004500 |
2 |
| Kynurenine 3-monooxygenase activity |
GO:0004502 |
193 |
| Monophenol monooxygenase activity |
GO:0004503 |
4 |
| Peptidylglycine monooxygenase activity |
GO:0004504 |
38 |
| Phenylalanine 4-monooxygenase activity |
GO:0004505 |
4 |
| Squalene monooxygenase activity |
GO:0004506 |
4 |
| Steroid 11-beta-monooxygenase activity |
GO:0004507 |
3 |
| Steroid 17-alpha-monooxygenase activity |
GO:0004508 |
4 |
| Steroid 21-monooxygenase activity |
GO:0004509 |
2 |
| Tryptophan 5-monooxygenase activity |
GO:0004510 |
10 |
| Tyrosine 3-monooxygenase activity |
GO:0004511 |
2 |
| Inositol-3-phosphate synthase activity |
GO:0004512 |
1 |
| Nicotinate-nucleotide adenylyltransferase activity |
GO:0004515 |
22 |
| Nitric-oxide synthase activity |
GO:0004517 |
1487 |
| Nuclease activity |
GO:0004518 |
424 |
| Endonuclease activity |
GO:0004519 |
3138 |
| Endodeoxyribonuclease activity |
GO:0004520 |
1746 |
| Endoribonuclease activity |
GO:0004521 |
37 |
| Ribonuclease H activity |
GO:0004523 |
275 |
| Ribonuclease III activity |
GO:0004525 |
489 |
| Ribonuclease P activity |
GO:0004526 |
1650 |
| Exonuclease activity |
GO:0004527 |
592 |
| Phosphodiesterase I activity |
GO:0004528 |
830 |
| Deoxyribonuclease I activity |
GO:0004530 |
720 |
| Deoxyribonuclease II activity |
GO:0004531 |
625 |
| Exoribonuclease activity |
GO:0004532 |
1204 |
| 5'-3' exoribonuclease activity |
GO:0004534 |
4 |
| Poly(A)-specific ribonuclease activity |
GO:0004535 |
967 |
| Deoxyribonuclease activity |
GO:0004536 |
1847 |
| Ribonuclease activity |
GO:0004540 |
1611 |
| Nucleoside diphosphate kinase activity |
GO:0004550 |
643 |
| Nucleotide diphosphatase activity |
GO:0004551 |
824 |
| Hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0004553 |
3081 |
| Alpha-galactosidase activity |
GO:0004557 |
4 |
| Alpha-glucosidase activity |
GO:0004558 |
8 |
| Alpha-mannosidase activity |
GO:0004559 |
608 |
| Alpha-L-fucosidase activity |
GO:0004560 |
3 |
| Alpha-N-acetylglucosaminidase activity |
GO:0004561 |
3 |
| Beta-N-acetylhexosaminidase activity |
GO:0004563 |
3 |
| Beta-galactosidase activity |
GO:0004565 |
1314 |
| Beta-glucuronidase activity |
GO:0004566 |
1124 |
| Chitinase activity |
GO:0004568 |
203 |
| Glycoprotein endo-alpha-1,2-mannosidase activity |
GO:0004569 |
4 |
| Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
GO:0004571 |
1278 |
| Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity |
GO:0004572 |
600 |
| Oligo-1,6-glucosidase activity |
GO:0004574 |
2 |
| Sucrose alpha-glucosidase activity |
GO:0004575 |
2 |
| Oligosaccharyl transferase activity |
GO:0004576 |
981 |
| N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity |
GO:0004577 |
3 |
| Dolichyl-diphosphooligosaccharide-protein glycotransferase activity |
GO:0004579 |
1142 |
| Dolichyl-phosphate beta-glucosyltransferase activity |
GO:0004581 |
1 |
| Dolichyl-phosphate beta-D-mannosyltransferase activity |
GO:0004582 |
4 |
| Ornithine decarboxylase activity |
GO:0004586 |
1 |
| Orotate phosphoribosyltransferase activity |
GO:0004588 |
594 |
| Orotidine-5'-phosphate decarboxylase activity |
GO:0004590 |
594 |
| Oxoglutarate dehydrogenase (succinyl-transferring) activity |
GO:0004591 |
1300 |
| Pantothenate kinase activity |
GO:0004594 |
736 |
| Pantetheine-phosphate adenylyltransferase activity |
GO:0004595 |
1 |
| Peptide-aspartate beta-dioxygenase activity |
GO:0004597 |
12 |
| Peptidylamidoglycolate lyase activity |
GO:0004598 |
38 |
| Peroxidase activity |
GO:0004601 |
1359 |
| Glutathione peroxidase activity |
GO:0004602 |
790 |
| Phenylethanolamine N-methyltransferase activity |
GO:0004603 |
2 |
| Phosphatidate cytidylyltransferase activity |
GO:0004605 |
14 |
| Phosphatidylethanolamine N-methyltransferase activity |
GO:0004608 |
1 |
| Phosphatidylserine decarboxylase activity |
GO:0004609 |
4 |
| Phosphoacetylglucosamine mutase activity |
GO:0004610 |
4 |
| Phosphoenolpyruvate carboxykinase activity |
GO:0004611 |
5 |
| Phosphoenolpyruvate carboxykinase (GTP) activity |
GO:0004613 |
20 |
| Phosphoglucomutase activity |
GO:0004614 |
12 |
| Phosphomannomutase activity |
GO:0004615 |
1 |
| Phosphogluconate dehydrogenase (decarboxylating) activity |
GO:0004616 |
1 |
| Phosphoglycerate kinase activity |
GO:0004618 |
5 |
| Phosphoglycerate mutase activity |
GO:0004619 |
1 |
| Phospholipase activity |
GO:0004620 |
205 |
| Glycosylphosphatidylinositol phospholipase D activity |
GO:0004621 |
823 |
| Lysophospholipase activity |
GO:0004622 |
33 |
| Phospholipase A2 activity |
GO:0004623 |
1545 |
| Phospholipase C activity |
GO:0004629 |
47 |
| Phospholipase D activity |
GO:0004630 |
843 |
| Phosphopantothenate--cysteine ligase activity |
GO:0004632 |
3 |
| Phosphopantothenoylcysteine decarboxylase activity |
GO:0004633 |
2 |
| Phosphoribosylamine-glycine ligase activity |
GO:0004637 |
317 |
| Phosphoribosylaminoimidazole carboxylase activity |
GO:0004638 |
857 |
| Phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
GO:0004639 |
857 |
| Phosphoribosylformylglycinamidine cyclo-ligase activity |
GO:0004641 |
317 |
| Phosphoribosylformylglycinamidine synthase activity |
GO:0004642 |
604 |
| Phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
GO:0004643 |
2 |
| Phosphoribosylglycinamide formyltransferase activity |
GO:0004644 |
317 |
| Phosphorylase activity |
GO:0004645 |
563 |
| Phosphoserine phosphatase activity |
GO:0004647 |
4 |
| Poly(ADP-ribose) glycohydrolase activity |
GO:0004649 |
4 |
| Polynucleotide 5'-phosphatase activity |
GO:0004651 |
1 |
| Polynucleotide adenylyltransferase activity |
GO:0004652 |
189 |
| Polypeptide N-acetylgalactosaminyltransferase activity |
GO:0004653 |
1657 |
| Porphobilinogen synthase activity |
GO:0004655 |
2 |
| Procollagen-proline 4-dioxygenase activity |
GO:0004656 |
109 |
| Proline dehydrogenase activity |
GO:0004657 |
61 |
| Propionyl-CoA carboxylase activity |
GO:0004658 |
36 |
| Prenyltransferase activity |
GO:0004659 |
668 |
| Protein farnesyltransferase activity |
GO:0004660 |
1 |
| Protein geranylgeranyltransferase activity |
GO:0004661 |
3 |
| CAAX-protein geranylgeranyltransferase activity |
GO:0004662 |
3 |
| Rab geranylgeranyltransferase activity |
GO:0004663 |
719 |
| Prostaglandin-endoperoxide synthase activity |
GO:0004666 |
14 |
| Prostaglandin-D synthase activity |
GO:0004667 |
2 |
| Protein-arginine deiminase activity |
GO:0004668 |
13 |
| Protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity |
GO:0004671 |
1626 |
| Protein kinase activity |
GO:0004672 |
5973 |
| Protein serine/threonine kinase activity |
GO:0004674 |
6614 |
| Transmembrane receptor protein serine/threonine kinase activity |
GO:0004675 |
488 |
| 3-phosphoinositide-dependent protein kinase activity |
GO:0004676 |
7 |
| DNA-dependent protein kinase activity |
GO:0004677 |
2029 |
| AMP-activated protein kinase activity |
GO:0004679 |
931 |
| Calmodulin-dependent protein kinase activity |
GO:0004683 |
2674 |
| Elongation factor-2 kinase activity |
GO:0004686 |
1822 |
| Myosin light chain kinase activity |
GO:0004687 |
1887 |
| Phosphorylase kinase activity |
GO:0004689 |
1591 |
| CAMP-dependent protein kinase activity |
GO:0004691 |
1525 |
| CGMP-dependent protein kinase activity |
GO:0004692 |
11 |
| Cyclin-dependent protein kinase activity |
GO:0004693 |
2239 |
| Eukaryotic translation initiation factor 2alpha kinase activity |
GO:0004694 |
947 |
| Protein kinase C activity |
GO:0004697 |
943 |
| Calcium-dependent protein kinase C activity |
GO:0004698 |
894 |
| Calcium-independent protein kinase C activity |
GO:0004699 |
6 |
| Receptor signaling protein serine/threonine kinase activity |
GO:0004702 |
1447 |
| G-protein coupled receptor kinase activity |
GO:0004703 |
18 |
| NF-kappaB-inducing kinase activity |
GO:0004704 |
285 |
| JUN kinase activity |
GO:0004705 |
22 |
| JUN kinase kinase kinase activity |
GO:0004706 |
653 |
| MAP kinase activity |
GO:0004707 |
1086 |
| MAP kinase kinase activity |
GO:0004708 |
686 |
| MAP kinase kinase kinase activity |
GO:0004709 |
1766 |
| Ribosomal protein S6 kinase activity |
GO:0004711 |
10 |
| Protein serine/threonine/tyrosine kinase activity |
GO:0004712 |
1428 |
| Protein tyrosine kinase activity |
GO:0004713 |
4260 |
| Transmembrane receptor protein tyrosine kinase activity |
GO:0004714 |
1197 |
| Non-membrane spanning protein tyrosine kinase activity |
GO:0004715 |
3471 |
| Receptor signaling protein tyrosine kinase activity |
GO:0004716 |
739 |
| Protein-L-isoaspartate (D-aspartate) O-methyltransferase activity |
GO:0004719 |
15 |
| Protein-lysine 6-oxidase activity |
GO:0004720 |
6 |
| Phosphoprotein phosphatase activity |
GO:0004721 |
2882 |
| Protein serine/threonine phosphatase activity |
GO:0004722 |
3873 |
| Calcium-dependent protein serine/threonine phosphatase activity |
GO:0004723 |
10 |
| Magnesium-dependent protein serine/threonine phosphatase activity |
GO:0004724 |
1719 |
| Protein tyrosine phosphatase activity |
GO:0004725 |
3739 |
| Non-membrane spanning protein tyrosine phosphatase activity |
GO:0004726 |
280 |
| Prenylated protein tyrosine phosphatase activity |
GO:0004727 |
4 |
| Receptor signaling protein tyrosine phosphatase activity |
GO:0004728 |
1 |
| Oxygen-dependent protoporphyrinogen oxidase activity |
GO:0004729 |
3 |
| Purine-nucleoside phosphorylase activity |
GO:0004731 |
569 |
| Pyridoxamine-phosphate oxidase activity |
GO:0004733 |
1135 |
| Pyrroline-5-carboxylate reductase activity |
GO:0004735 |
6 |
| Pyruvate carboxylase activity |
GO:0004736 |
3 |
| Pyruvate dehydrogenase activity |
GO:0004738 |
229 |
| Pyruvate dehydrogenase (acetyl-transferring) activity |
GO:0004739 |
229 |
| Pyruvate dehydrogenase (acetyl-transferring) kinase activity |
GO:0004740 |
1184 |
| [pyruvate dehydrogenase (lipoamide)] phosphatase activity |
GO:0004741 |
1721 |
| Pyruvate kinase activity |
GO:0004743 |
9 |
| Retinal isomerase activity |
GO:0004744 |
5 |
| Retinol dehydrogenase activity |
GO:0004745 |
1100 |
| Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
GO:0004748 |
516 |
| Ribose phosphate diphosphokinase activity |
GO:0004749 |
9 |
| Ribulose-phosphate 3-epimerase activity |
GO:0004750 |
53 |
| Ribose-5-phosphate isomerase activity |
GO:0004751 |
3 |
| Selenide, water dikinase activity |
GO:0004756 |
3 |
| Serine C-palmitoyltransferase activity |
GO:0004758 |
2011 |
| Serine-pyruvate transaminase activity |
GO:0004760 |
2 |
| Spermidine synthase activity |
GO:0004766 |
2 |
| Sphingomyelin phosphodiesterase activity |
GO:0004767 |
77 |
| Stearoyl-CoA 9-desaturase activity |
GO:0004768 |
822 |
| Steroid delta-isomerase activity |
GO:0004769 |
1 |
| Sterol esterase activity |
GO:0004771 |
7 |
| Sterol O-acyltransferase activity |
GO:0004772 |
1407 |
| Steryl-sulfatase activity |
GO:0004773 |
3 |
| Succinate-CoA ligase (ADP-forming) activity |
GO:0004775 |
5 |
| Succinate-CoA ligase (GDP-forming) activity |
GO:0004776 |
4 |
| Succinate-semialdehyde dehydrogenase (NAD+) activity |
GO:0004777 |
708 |
| Succinyl-CoA hydrolase activity |
GO:0004778 |
2 |
| Sulfate adenylyltransferase (ATP) activity |
GO:0004781 |
9 |
| Sulfinoalanine decarboxylase activity |
GO:0004782 |
591 |
| Superoxide dismutase activity |
GO:0004784 |
685 |
| Thiamine diphosphokinase activity |
GO:0004788 |
1 |
| Thioether S-methyltransferase activity |
GO:0004790 |
1026 |
| Thioredoxin-disulfide reductase activity |
GO:0004791 |
1301 |
| Thiosulfate sulfurtransferase activity |
GO:0004792 |
3 |
| L-threonine ammonia-lyase activity |
GO:0004794 |
360 |
| Thromboxane-A synthase activity |
GO:0004796 |
1 |
| Thymidine kinase activity |
GO:0004797 |
106 |
| Thymidylate kinase activity |
GO:0004798 |
2 |
| Thyroxine 5'-deiodinase activity |
GO:0004800 |
11 |
| Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity |
GO:0004801 |
2 |
| Transketolase activity |
GO:0004802 |
38 |
| Transposase activity |
GO:0004803 |
874 |
| Triglyceride lipase activity |
GO:0004806 |
658 |
| Triose-phosphate isomerase activity |
GO:0004807 |
1 |
| TRNA (guanine-N2-)-methyltransferase activity |
GO:0004809 |
9 |
| Aminoacyl-tRNA ligase activity |
GO:0004812 |
22 |
| Alanine-tRNA ligase activity |
GO:0004813 |
784 |
| Arginine-tRNA ligase activity |
GO:0004814 |
1 |
| Aspartate-tRNA ligase activity |
GO:0004815 |
4 |
| Asparagine-tRNA ligase activity |
GO:0004816 |
6 |
| Cysteine-tRNA ligase activity |
GO:0004817 |
1 |
| Glutamate-tRNA ligase activity |
GO:0004818 |
6 |
| Glutamine-tRNA ligase activity |
GO:0004819 |
6 |
| Glycine-tRNA ligase activity |
GO:0004820 |
1 |
| Histidine-tRNA ligase activity |
GO:0004821 |
4 |
| Isoleucine-tRNA ligase activity |
GO:0004822 |
5 |
| Methionine-tRNA ligase activity |
GO:0004825 |
9 |
| Phenylalanine-tRNA ligase activity |
GO:0004826 |
640 |
| Proline-tRNA ligase activity |
GO:0004827 |
5 |
| Serine-tRNA ligase activity |
GO:0004828 |
2 |
| Threonine-tRNA ligase activity |
GO:0004829 |
811 |
| Tryptophan-tRNA ligase activity |
GO:0004830 |
4 |
| Tyrosine-tRNA ligase activity |
GO:0004831 |
478 |
| Valine-tRNA ligase activity |
GO:0004832 |
5 |
| Tryptophan 2,3-dioxygenase activity |
GO:0004833 |
3 |
| Tubulin-tyrosine ligase activity |
GO:0004835 |
115 |
| L-tyrosine:2-oxoglutarate aminotransferase activity |
GO:0004838 |
746 |
| Ubiquitin activating enzyme activity |
GO:0004839 |
9 |
| Ubiquitin-protein ligase activity |
GO:0004842 |
6150 |
| Ubiquitin-specific protease activity |
GO:0004843 |
4431 |
| Uracil DNA N-glycosylase activity |
GO:0004844 |
685 |
| Uridine kinase activity |
GO:0004849 |
12 |
| Uridine phosphorylase activity |
GO:0004850 |
6 |
| Uroporphyrinogen-III synthase activity |
GO:0004852 |
2 |
| Uroporphyrinogen decarboxylase activity |
GO:0004853 |
1 |
| Xanthine dehydrogenase activity |
GO:0004854 |
252 |
| Xanthine oxidase activity |
GO:0004855 |
243 |
| Xylulokinase activity |
GO:0004856 |
2 |
| Enzyme inhibitor activity |
GO:0004857 |
225 |
| Phospholipase inhibitor activity |
GO:0004859 |
16 |
| Protein kinase inhibitor activity |
GO:0004860 |
2703 |
| Cyclin-dependent protein kinase inhibitor activity |
GO:0004861 |
321 |
| CAMP-dependent protein kinase inhibitor activity |
GO:0004862 |
305 |
| Protein phosphatase inhibitor activity |
GO:0004864 |
1152 |
| Protein serine/threonine phosphatase inhibitor activity |
GO:0004865 |
26 |
| Endopeptidase inhibitor activity |
GO:0004866 |
906 |
| Serine-type endopeptidase inhibitor activity |
GO:0004867 |
3097 |
| Cysteine-type endopeptidase inhibitor activity |
GO:0004869 |
360 |
| Signal transducer activity |
GO:0004871 |
5555 |
| Receptor activity |
GO:0004872 |
5808 |
| Asialoglycoprotein receptor activity |
GO:0004873 |
2553 |
| Aryl hydrocarbon receptor activity |
GO:0004874 |
73 |
| Complement receptor activity |
GO:0004875 |
6 |
| Complement component C3b receptor activity |
GO:0004877 |
806 |
| Complement component C5a receptor activity |
GO:0004878 |
342 |
| Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
GO:0004879 |
2905 |
| Androgen receptor activity |
GO:0004882 |
18 |
| Glucocorticoid receptor activity |
GO:0004883 |
9 |
| 9-cis retinoic acid receptor activity |
GO:0004886 |
8 |
| Thyroid hormone receptor activity |
GO:0004887 |
149 |
| Transmembrane signaling receptor activity |
GO:0004888 |
4614 |
| Acetylcholine-activated cation-selective channel activity |
GO:0004889 |
1911 |
| GABA-A receptor activity |
GO:0004890 |
107 |
| Cytokine receptor activity |
GO:0004896 |
3275 |
| Ciliary neurotrophic factor receptor activity |
GO:0004897 |
1371 |
| Erythropoietin receptor activity |
GO:0004900 |
5 |
| Interferon receptor activity |
GO:0004904 |
1139 |
| Type I interferon receptor activity |
GO:0004905 |
1632 |
| Interferon-gamma receptor activity |
GO:0004906 |
121 |
| Interleukin-1 receptor activity |
GO:0004908 |
528 |
| Interleukin-1, Type I, activating receptor activity |
GO:0004909 |
506 |
| Interleukin-1, Type II, blocking receptor activity |
GO:0004910 |
5 |
| Interleukin-2 receptor activity |
GO:0004911 |
237 |
| Interleukin-3 receptor activity |
GO:0004912 |
9 |
| Interleukin-4 receptor activity |
GO:0004913 |
191 |
| Interleukin-5 receptor activity |
GO:0004914 |
229 |
| Interleukin-6 receptor activity |
GO:0004915 |
1362 |
| Interleukin-7 receptor activity |
GO:0004917 |
5 |
| Interleukin-10 receptor activity |
GO:0004920 |
452 |
| Interleukin-11 receptor activity |
GO:0004921 |
6 |
| Leukemia inhibitory factor receptor activity |
GO:0004923 |
14 |
| Oncostatin-M receptor activity |
GO:0004924 |
894 |
| Prolactin receptor activity |
GO:0004925 |
109 |
| G-protein coupled receptor activity |
GO:0004930 |
5785 |
| Extracellular ATP-gated cation channel activity |
GO:0004931 |
21 |
| Alpha1-adrenergic receptor activity |
GO:0004937 |
940 |
| Alpha2-adrenergic receptor activity |
GO:0004938 |
11 |
| Beta-adrenergic receptor activity |
GO:0004939 |
18 |
| Beta1-adrenergic receptor activity |
GO:0004940 |
5 |
| Beta2-adrenergic receptor activity |
GO:0004941 |
1 |
| C5a anaphylatoxin receptor activity |
GO:0004944 |
342 |
| Angiotensin type II receptor activity |
GO:0004945 |
10 |
| Bombesin receptor activity |
GO:0004946 |
1 |
| Bradykinin receptor activity |
GO:0004947 |
46 |
| Calcitonin receptor activity |
GO:0004948 |
11 |
| Cannabinoid receptor activity |
GO:0004949 |
13 |
| Chemokine receptor activity |
GO:0004950 |
1712 |
| Cholecystokinin receptor activity |
GO:0004951 |
4 |
| Dopamine receptor activity |
GO:0004952 |
13 |
| Prostaglandin D receptor activity |
GO:0004956 |
7 |
| Prostaglandin E receptor activity |
GO:0004957 |
16 |
| Prostaglandin F receptor activity |
GO:0004958 |
7 |
| Thromboxane receptor activity |
GO:0004960 |
1067 |
| Thromboxane A2 receptor activity |
GO:0004961 |
1067 |
| Endothelin receptor activity |
GO:0004962 |
8 |
| Follicle-stimulating hormone receptor activity |
GO:0004963 |
2 |
| Luteinizing hormone receptor activity |
GO:0004964 |
3 |
| G-protein coupled GABA receptor activity |
GO:0004965 |
26 |
| Glucagon receptor activity |
GO:0004967 |
10 |
| Gonadotropin-releasing hormone receptor activity |
GO:0004968 |
12 |
| Histamine receptor activity |
GO:0004969 |
1350 |
| Ionotropic glutamate receptor activity |
GO:0004970 |
204 |
| Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity |
GO:0004971 |
35 |
| N-methyl-D-aspartate selective glutamate receptor activity |
GO:0004972 |
161 |
| Leukotriene receptor activity |
GO:0004974 |
634 |
| Melanocortin receptor activity |
GO:0004977 |
16 |
| Corticotropin receptor activity |
GO:0004978 |
11 |
| Beta-endorphin receptor activity |
GO:0004979 |
1710 |
| Melanocyte-stimulating hormone receptor activity |
GO:0004980 |
5 |
| Neuropeptide Y receptor activity |
GO:0004983 |
1467 |
| Olfactory receptor activity |
GO:0004984 |
1814 |
| Opioid receptor activity |
GO:0004985 |
820 |
| Oxytocin receptor activity |
GO:0004990 |
16 |
| Platelet activating factor receptor activity |
GO:0004992 |
1118 |
| Serotonin receptor activity |
GO:0004993 |
695 |
| Somatostatin receptor activity |
GO:0004994 |
675 |
| Tachykinin receptor activity |
GO:0004995 |
23 |
| Thyroid-stimulating hormone receptor activity |
GO:0004996 |
5 |
| Transferrin receptor activity |
GO:0004998 |
7 |
| Vasoactive intestinal polypeptide receptor activity |
GO:0004999 |
938 |
| Vasopressin receptor activity |
GO:0005000 |
705 |
| Transmembrane receptor protein tyrosine phosphatase activity |
GO:0005001 |
605 |
| Ephrin receptor activity |
GO:0005003 |
928 |
| GPI-linked ephrin receptor activity |
GO:0005004 |
180 |
| Transmembrane-ephrin receptor activity |
GO:0005005 |
807 |
| Epidermal growth factor-activated receptor activity |
GO:0005006 |
9 |
| Fibroblast growth factor-activated receptor activity |
GO:0005007 |
1065 |
| Hepatocyte growth factor-activated receptor activity |
GO:0005008 |
353 |
| Insulin-activated receptor activity |
GO:0005009 |
8 |
| Insulin-like growth factor-activated receptor activity |
GO:0005010 |
55 |
| Macrophage colony-stimulating factor receptor activity |
GO:0005011 |
12 |
| Platelet-derived growth factor alpha-receptor activity |
GO:0005018 |
11 |
| Platelet-derived growth factor beta-receptor activity |
GO:0005019 |
3 |
| Stem cell factor receptor activity |
GO:0005020 |
6 |
| Vascular endothelial growth factor-activated receptor activity |
GO:0005021 |
754 |
| Transforming growth factor beta-activated receptor activity |
GO:0005024 |
1385 |
| Transforming growth factor beta receptor activity, type I |
GO:0005025 |
479 |
| Transforming growth factor beta receptor activity, type II |
GO:0005026 |
5 |
| Neurotrophin receptor activity |
GO:0005030 |
7 |
| Tumor necrosis factor-activated receptor activity |
GO:0005031 |
831 |
| Osmosensor activity |
GO:0005034 |
1 |
| Death receptor activity |
GO:0005035 |
321 |
| Low-density lipoprotein receptor activity |
GO:0005041 |
2042 |
| Netrin receptor activity |
GO:0005042 |
20 |
| Scavenger receptor activity |
GO:0005044 |
2115 |
| KDEL sequence binding |
GO:0005046 |
5 |
| Signal recognition particle binding |
GO:0005047 |
103 |
| Signal sequence binding |
GO:0005048 |
7 |
| Peroxisome matrix targeting signal-1 binding |
GO:0005052 |
625 |
| Laminin receptor activity |
GO:0005055 |
8 |
| Receptor signaling protein activity |
GO:0005057 |
1816 |
| Transmembrane receptor protein tyrosine kinase adaptor activity |
GO:0005068 |
148 |
| SH3/SH2 adaptor activity |
GO:0005070 |
3274 |
| Transforming growth factor beta receptor, cytoplasmic mediator activity |
GO:0005072 |
11 |
| MAP-kinase scaffold activity |
GO:0005078 |
2183 |
| Protein kinase C binding |
GO:0005080 |
2876 |
| Small GTPase regulator activity |
GO:0005083 |
2308 |
| Guanyl-nucleotide exchange factor activity |
GO:0005085 |
3717 |
| ARF guanyl-nucleotide exchange factor activity |
GO:0005086 |
975 |
| Ran guanyl-nucleotide exchange factor activity |
GO:0005087 |
249 |
| Ras guanyl-nucleotide exchange factor activity |
GO:0005088 |
845 |
| Rho guanyl-nucleotide exchange factor activity |
GO:0005089 |
3974 |
| GDP-dissociation inhibitor activity |
GO:0005092 |
14 |
| Rab GDP-dissociation inhibitor activity |
GO:0005093 |
3 |
| Rho GDP-dissociation inhibitor activity |
GO:0005094 |
8 |
| GTPase inhibitor activity |
GO:0005095 |
211 |
| GTPase activator activity |
GO:0005096 |
3981 |
| Rab GTPase activator activity |
GO:0005097 |
3605 |
| Ran GTPase activator activity |
GO:0005098 |
145 |
| Ras GTPase activator activity |
GO:0005099 |
997 |
| Rho GTPase activator activity |
GO:0005100 |
1555 |
| Receptor binding |
GO:0005102 |
5724 |
| Fibroblast growth factor receptor binding |
GO:0005104 |
826 |
| Type 1 fibroblast growth factor receptor binding |
GO:0005105 |
15 |
| Frizzled binding |
GO:0005109 |
872 |
| Frizzled-2 binding |
GO:0005110 |
2 |
| Type 2 fibroblast growth factor receptor binding |
GO:0005111 |
10 |
| Notch binding |
GO:0005112 |
1795 |
| Patched binding |
GO:0005113 |
35 |
| Type II transforming growth factor beta receptor binding |
GO:0005114 |
47 |
| Smoothened binding |
GO:0005119 |
30 |
| Toll binding |
GO:0005121 |
2 |
| Death receptor binding |
GO:0005123 |
2366 |
| Cytokine activity |
GO:0005125 |
4068 |
| Cytokine receptor binding |
GO:0005126 |
10 |
| Ciliary neurotrophic factor receptor binding |
GO:0005127 |
21 |
| Erythropoietin receptor binding |
GO:0005128 |
1131 |
| Granulocyte colony-stimulating factor receptor binding |
GO:0005130 |
1 |
| Growth hormone receptor binding |
GO:0005131 |
19 |
| Interferon-alpha/beta receptor binding |
GO:0005132 |
4 |
| Interleukin-2 receptor binding |
GO:0005134 |
407 |
| Interleukin-3 receptor binding |
GO:0005135 |
1133 |
| Interleukin-4 receptor binding |
GO:0005136 |
1 |
| Interleukin-6 receptor binding |
GO:0005138 |
1484 |
| Interleukin-7 receptor binding |
GO:0005139 |
3 |
| Interleukin-10 receptor binding |
GO:0005141 |
576 |
| Interleukin-11 receptor binding |
GO:0005142 |
893 |
| Interleukin-12 receptor binding |
GO:0005143 |
1084 |
| Interleukin-13 receptor binding |
GO:0005144 |
2 |
| Leukemia inhibitory factor receptor binding |
GO:0005146 |
356 |
| Oncostatin-M receptor binding |
GO:0005147 |
1 |
| Prolactin receptor binding |
GO:0005148 |
392 |
| Interleukin-1 receptor binding |
GO:0005149 |
1643 |
| Interleukin-1, Type I receptor binding |
GO:0005150 |
1 |
| Interleukin-1, Type II receptor binding |
GO:0005151 |
6 |
| Interleukin-1 receptor antagonist activity |
GO:0005152 |
13 |
| Epidermal growth factor receptor binding |
GO:0005154 |
2109 |
| Macrophage colony-stimulating factor receptor binding |
GO:0005157 |
14 |
| Insulin receptor binding |
GO:0005158 |
1774 |
| Insulin-like growth factor receptor binding |
GO:0005159 |
829 |
| Transforming growth factor beta receptor binding |
GO:0005160 |
2827 |
| Platelet-derived growth factor receptor binding |
GO:0005161 |
592 |
| Tumor necrosis factor receptor binding |
GO:0005164 |
1961 |
| Neurotrophin p75 receptor binding |
GO:0005166 |
1 |
| Neurotrophin TRKA receptor binding |
GO:0005168 |
820 |
| Neurotrophin TRKB receptor binding |
GO:0005169 |
3 |
| Vascular endothelial growth factor receptor binding |
GO:0005172 |
8 |
| Stem cell factor receptor binding |
GO:0005173 |
981 |
| CD40 receptor binding |
GO:0005174 |
6 |
| ErbB-2 class receptor binding |
GO:0005176 |
6 |
| Integrin binding |
GO:0005178 |
3885 |
| Hormone activity |
GO:0005179 |
3230 |
| Neuropeptide hormone activity |
GO:0005184 |
16 |
| Neurohypophyseal hormone activity |
GO:0005185 |
1 |
| Structural molecule activity |
GO:0005198 |
4535 |
| Structural constituent of cell wall |
GO:0005199 |
6 |
| Structural constituent of cytoskeleton |
GO:0005200 |
2147 |
| Extracellular matrix structural constituent |
GO:0005201 |
2473 |
| Structural constituent of eye lens |
GO:0005212 |
114 |
| Transporter activity |
GO:0005215 |
5351 |
| Ion channel activity |
GO:0005216 |
3816 |
| Intracellular ligand-gated calcium channel activity |
GO:0005218 |
19 |
| Ryanodine-sensitive calcium-release channel activity |
GO:0005219 |
53 |
| Inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity |
GO:0005220 |
23 |
| Intracellular cAMP activated cation channel activity |
GO:0005222 |
1181 |
| Intracellular cGMP activated cation channel activity |
GO:0005223 |
833 |
| ATP-binding and phosphorylation-dependent chloride channel activity |
GO:0005224 |
11 |
| Calcium activated cation channel activity |
GO:0005227 |
707 |
| Intracellular calcium activated chloride channel activity |
GO:0005229 |
701 |
| Extracellular ligand-gated ion channel activity |
GO:0005230 |
1041 |
| Excitatory extracellular ligand-gated ion channel activity |
GO:0005231 |
907 |
| Serotonin-activated cation-selective channel activity |
GO:0005232 |
168 |
| Extracellular-glutamate-gated ion channel activity |
GO:0005234 |
220 |
| Inhibitory extracellular ligand-gated ion channel activity |
GO:0005237 |
8 |
| Inward rectifier potassium channel activity |
GO:0005242 |
876 |
| Gap junction channel activity |
GO:0005243 |
2327 |
| Voltage-gated ion channel activity |
GO:0005244 |
915 |
| Voltage-gated calcium channel activity |
GO:0005245 |
3037 |
| Calcium channel regulator activity |
GO:0005246 |
2088 |
| Voltage-gated chloride channel activity |
GO:0005247 |
1312 |
| Voltage-gated sodium channel activity |
GO:0005248 |
2123 |
| Voltage-gated potassium channel activity |
GO:0005249 |
2212 |
| A-type (transient outward) potassium channel activity |
GO:0005250 |
12 |
| Delayed rectifier potassium channel activity |
GO:0005251 |
131 |
| Open rectifier potassium channel activity |
GO:0005252 |
156 |
| Anion channel activity |
GO:0005253 |
794 |
| Chloride channel activity |
GO:0005254 |
2648 |
| Channel-conductance-controlling ATPase activity |
GO:0005260 |
11 |
| Cation channel activity |
GO:0005261 |
806 |
| Calcium channel activity |
GO:0005262 |
3434 |
| Potassium channel activity |
GO:0005267 |
883 |
| Sodium channel activity |
GO:0005272 |
120 |
| Amine transmembrane transporter activity |
GO:0005275 |
8 |
| Acetylcholine transmembrane transporter activity |
GO:0005277 |
4 |
| Hydrogen:amino acid symporter activity |
GO:0005280 |
1058 |
| Sodium:amino acid symporter activity |
GO:0005283 |
21 |
| High affinity arginine transmembrane transporter activity |
GO:0005289 |
199 |
| L-histidine transmembrane transporter activity |
GO:0005290 |
12 |
| Proline:sodium symporter activity |
GO:0005298 |
9 |
| Creatine transporter activity |
GO:0005308 |
4 |
| Creatine:sodium symporter activity |
GO:0005309 |
4 |
| Dicarboxylic acid transmembrane transporter activity |
GO:0005310 |
4 |
| L-glutamate transmembrane transporter activity |
GO:0005313 |
234 |
| High-affinity glutamate transmembrane transporter activity |
GO:0005314 |
4 |
| Inorganic phosphate transmembrane transporter activity |
GO:0005315 |
8 |
| High affinity inorganic phosphate:sodium symporter activity |
GO:0005316 |
2 |
| Lipid transporter activity |
GO:0005319 |
2108 |
| Long-chain fatty acid transporter activity |
GO:0005324 |
4 |
| Peroxisomal fatty-acyl-CoA transporter activity |
GO:0005325 |
4 |
| Neurotransmitter transporter activity |
GO:0005326 |
18 |
| Neurotransmitter:sodium symporter activity |
GO:0005328 |
1221 |
| Dopamine transmembrane transporter activity |
GO:0005329 |
8 |
| Dopamine:sodium symporter activity |
GO:0005330 |
3 |
| Gamma-aminobutyric acid:sodium symporter activity |
GO:0005332 |
3 |
| Norepinephrine transmembrane transporter activity |
GO:0005333 |
10 |
| Norepinephrine:sodium symporter activity |
GO:0005334 |
7 |
| Serotonin:sodium symporter activity |
GO:0005335 |
1036 |
| Nucleoside transmembrane transporter activity |
GO:0005337 |
18 |
| Nucleotide-sugar transmembrane transporter activity |
GO:0005338 |
12 |
| Oxygen transporter activity |
GO:0005344 |
548 |
| Purine base transmembrane transporter activity |
GO:0005345 |
2 |
| ATP transmembrane transporter activity |
GO:0005347 |
7 |
| Pyrimidine base transmembrane transporter activity |
GO:0005350 |
2 |
| Sugar:hydrogen symporter activity |
GO:0005351 |
812 |
| Fructose transmembrane transporter activity |
GO:0005353 |
4 |
| Glucose transmembrane transporter activity |
GO:0005355 |
1284 |
| Taurine:sodium symporter activity |
GO:0005369 |
16 |
| Water transmembrane transporter activity |
GO:0005372 |
897 |
| Copper ion transmembrane transporter activity |
GO:0005375 |
1866 |
| Iron ion transmembrane transporter activity |
GO:0005381 |
7 |
| Manganese ion transmembrane transporter activity |
GO:0005384 |
719 |
| Zinc ion transmembrane transporter activity |
GO:0005385 |
1780 |
| Calcium-transporting ATPase activity |
GO:0005388 |
85 |
| Sodium:potassium-exchanging ATPase activity |
GO:0005391 |
1271 |
| Glucose:sodium symporter activity |
GO:0005412 |
82 |
| Nucleoside:sodium symporter activity |
GO:0005415 |
760 |
| Proton-dependent oligopeptide secondary active transmembrane transporter activity |
GO:0005427 |
1042 |
| Calcium:sodium antiporter activity |
GO:0005432 |
227 |
| Sodium:phosphate symporter activity |
GO:0005436 |
103 |
| Inorganic anion exchanger activity |
GO:0005452 |
2804 |
| CMP-N-acetylneuraminate transmembrane transporter activity |
GO:0005456 |
2 |
| UDP-galactose transmembrane transporter activity |
GO:0005459 |
11 |
| Pyruvate secondary active transmembrane transporter activity |
GO:0005477 |
786 |
| Soluble NSF attachment protein activity |
GO:0005483 |
164 |
| SNAP receptor activity |
GO:0005484 |
3368 |
| Nucleocytoplasmic transporter activity |
GO:0005487 |
1120 |
| Steroid binding |
GO:0005496 |
1837 |
| Androgen binding |
GO:0005497 |
23 |
| Vitamin D binding |
GO:0005499 |
8 |
| Retinoid binding |
GO:0005501 |
539 |
| 11-cis retinal binding |
GO:0005502 |
7 |
| All-trans retinal binding |
GO:0005503 |
9 |
| Fatty acid binding |
GO:0005504 |
2106 |
| Iron ion binding |
GO:0005506 |
5289 |
| Copper ion binding |
GO:0005507 |
1480 |
| Calcium ion binding |
GO:0005509 |
7259 |
| Protein binding |
GO:0005515 |
10348 |
| Calmodulin binding |
GO:0005516 |
5247 |
| Collagen binding |
GO:0005518 |
3298 |
| Cytoskeletal regulatory protein binding |
GO:0005519 |
5 |
| Insulin-like growth factor binding |
GO:0005520 |
401 |
| Lamin binding |
GO:0005521 |
1207 |
| Profilin binding |
GO:0005522 |
59 |
| Tropomyosin binding |
GO:0005523 |
834 |
| ATP binding |
GO:0005524 |
8575 |
| GTP binding |
GO:0005525 |
6438 |
| Macrolide binding |
GO:0005527 |
5 |
| FK506 binding |
GO:0005528 |
1810 |
| Galactose binding |
GO:0005534 |
12 |
| Glucose binding |
GO:0005536 |
280 |
| Mannose binding |
GO:0005537 |
1188 |
| Glycosaminoglycan binding |
GO:0005539 |
78 |
| Hyaluronic acid binding |
GO:0005540 |
879 |
| Folic acid binding |
GO:0005542 |
209 |
| Phospholipid binding |
GO:0005543 |
3543 |
| Calcium-dependent phospholipid binding |
GO:0005544 |
1520 |
| 1-phosphatidylinositol binding |
GO:0005545 |
3095 |
| Phosphatidylinositol-4,5-bisphosphate binding |
GO:0005546 |
1577 |
| Phosphatidylinositol-3,4,5-trisphosphate binding |
GO:0005547 |
1489 |
| Phospholipid transporter activity |
GO:0005548 |
20 |
| Chemokine activity |
GO:0008009 |
2969 |
| Beta-catenin binding |
GO:0008013 |
2208 |
| Microtubule binding |
GO:0008017 |
5879 |
| G-protein coupled photoreceptor activity |
GO:0008020 |
24 |
| Protein C-terminus binding |
GO:0008022 |
4322 |
| ATP-dependent helicase activity |
GO:0008026 |
3459 |
| Monocarboxylic acid transmembrane transporter activity |
GO:0008028 |
65 |
| High-density lipoprotein particle binding |
GO:0008035 |
1276 |
| Axon guidance receptor activity |
GO:0008046 |
368 |
| Enzyme activator activity |
GO:0008047 |
3225 |
| Calcium sensitive guanylate cyclase activator activity |
GO:0008048 |
770 |
| ARF GTPase activator activity |
GO:0008060 |
136 |
| Chitin binding |
GO:0008061 |
206 |
| Glutamate receptor activity |
GO:0008066 |
999 |
| Translation termination factor activity |
GO:0008079 |
4 |
| N-acetyltransferase activity |
GO:0008080 |
1491 |
| Phosphoric diester hydrolase activity |
GO:0008081 |
1072 |
| Growth factor activity |
GO:0008083 |
4206 |
| Cytoskeletal protein binding |
GO:0008092 |
2455 |
| Cytoskeletal adaptor activity |
GO:0008093 |
1892 |
| DNA-dependent ATPase activity |
GO:0008094 |
3472 |
| 5S rRNA binding |
GO:0008097 |
5 |
| Alcohol dehydrogenase (NADP+) activity |
GO:0008106 |
2 |
| Galactoside 2-alpha-L-fucosyltransferase activity |
GO:0008107 |
2188 |
| N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity |
GO:0008109 |
3 |
| Alpha-methylacyl-CoA racemase activity |
GO:0008111 |
121 |
| Nicotinamide N-methyltransferase activity |
GO:0008112 |
1 |
| Peptide-methionine-(S)-S-oxide reductase activity |
GO:0008113 |
3 |
| Sarcosine oxidase activity |
GO:0008115 |
566 |
| Prostaglandin-I synthase activity |
GO:0008116 |
1737 |
| Sphinganine-1-phosphate aldolase activity |
GO:0008117 |
548 |
| Thiopurine S-methyltransferase activity |
GO:0008119 |
1790 |
| Ubiquinol-cytochrome-c reductase activity |
GO:0008121 |
493 |
| Cholesterol 7-alpha-monooxygenase activity |
GO:0008123 |
131 |
| 4-alpha-hydroxytetrahydrobiopterin dehydratase activity |
GO:0008124 |
1 |
| Quercetin 2,3-dioxygenase activity |
GO:0008127 |
3 |
| Primary amine oxidase activity |
GO:0008131 |
15 |
| Transcription factor binding |
GO:0008134 |
5662 |
| Translation factor activity, nucleic acid binding |
GO:0008135 |
3024 |
| NADH dehydrogenase (ubiquinone) activity |
GO:0008137 |
2066 |
| Protein tyrosine/serine/threonine phosphatase activity |
GO:0008138 |
1907 |
| Nuclear localization sequence binding |
GO:0008139 |
92 |
| CAMP response element binding protein binding |
GO:0008140 |
1722 |
| Oxysterol binding |
GO:0008142 |
31 |
| Poly(A) RNA binding |
GO:0008143 |
156 |
| Drug binding |
GO:0008144 |
2429 |
| Sulfotransferase activity |
GO:0008146 |
1923 |
| Structural constituent of bone |
GO:0008147 |
9 |
| Protein phosphatase 1 binding |
GO:0008157 |
2267 |
| Hedgehog receptor activity |
GO:0008158 |
1128 |
| Protein tyrosine phosphatase activator activity |
GO:0008160 |
3 |
| Methyltransferase activity |
GO:0008168 |
4487 |
| N-methyltransferase activity |
GO:0008170 |
7 |
| O-methyltransferase activity |
GO:0008171 |
833 |
| RNA methyltransferase activity |
GO:0008173 |
818 |
| TRNA methyltransferase activity |
GO:0008175 |
524 |
| TRNA (guanine-N7-)-methyltransferase activity |
GO:0008176 |
2 |
| Succinate dehydrogenase (ubiquinone) activity |
GO:0008177 |
104 |
| Adenylate cyclase binding |
GO:0008179 |
564 |
| Glycogen phosphorylase activity |
GO:0008184 |
13 |
| RNA-dependent ATPase activity |
GO:0008186 |
8 |
| Poly-pyrimidine tract binding |
GO:0008187 |
9 |
| Neuropeptide receptor activity |
GO:0008188 |
598 |
| Eukaryotic initiation factor 4E binding |
GO:0008190 |
590 |
| Metalloendopeptidase inhibitor activity |
GO:0008191 |
31 |
| TRNA guanylyltransferase activity |
GO:0008193 |
485 |
| UDP-glycosyltransferase activity |
GO:0008194 |
11 |
| Phosphatidate phosphatase activity |
GO:0008195 |
1683 |
| Ferrous iron binding |
GO:0008198 |
3174 |
| Ferric iron binding |
GO:0008199 |
1947 |
| Ion channel inhibitor activity |
GO:0008200 |
18 |
| Heparin binding |
GO:0008201 |
4124 |
| G-protein coupled amine receptor activity |
GO:0008227 |
10 |
| Peptidase activity |
GO:0008233 |
3484 |
| Cysteine-type peptidase activity |
GO:0008234 |
4499 |
| Metalloexopeptidase activity |
GO:0008235 |
17 |
| Serine-type peptidase activity |
GO:0008236 |
1902 |
| Metallopeptidase activity |
GO:0008237 |
3511 |
| Exopeptidase activity |
GO:0008238 |
2 |
| Dipeptidyl-peptidase activity |
GO:0008239 |
26 |
| Tripeptidyl-peptidase activity |
GO:0008240 |
8 |
| Peptidyl-dipeptidase activity |
GO:0008241 |
7 |
| Omega peptidase activity |
GO:0008242 |
1899 |
| TRNA-specific adenosine deaminase activity |
GO:0008251 |
159 |
| Nucleotidase activity |
GO:0008252 |
1 |
| 5'-nucleotidase activity |
GO:0008253 |
2148 |
| 3'-nucleotidase activity |
GO:0008254 |
730 |
| 3-oxoacid CoA-transferase activity |
GO:0008260 |
1 |
| Importin-alpha export receptor activity |
GO:0008262 |
1 |
| Pyrimidine-specific mismatch base pair DNA N-glycosylase activity |
GO:0008263 |
112 |
| Poly(U) RNA binding |
GO:0008266 |
32 |
| Poly-glutamine tract binding |
GO:0008267 |
10 |
| Zinc ion binding |
GO:0008270 |
8260 |
| Secondary active sulfate transmembrane transporter activity |
GO:0008271 |
1249 |
| Calcium, potassium:sodium antiporter activity |
GO:0008273 |
478 |
| Protein methyltransferase activity |
GO:0008276 |
589 |
| Sulfonylurea receptor activity |
GO:0008281 |
5 |
| Lipid binding |
GO:0008289 |
5155 |
| Calcium- and calmodulin-responsive adenylate cyclase activity |
GO:0008294 |
289 |
| 3'-5'-exodeoxyribonuclease activity |
GO:0008296 |
1 |
| DNA binding, bending |
GO:0008301 |
1353 |
| Structural constituent of muscle |
GO:0008307 |
1276 |
| Voltage-gated anion channel activity |
GO:0008308 |
6 |
| Double-stranded DNA specific exodeoxyribonuclease activity |
GO:0008309 |
4 |
| Single-stranded DNA specific 3'-5' exodeoxyribonuclease activity |
GO:0008310 |
612 |
| Double-stranded DNA specific 3'-5' exodeoxyribonuclease activity |
GO:0008311 |
2 |
| 7S RNA binding |
GO:0008312 |
646 |
| Protein prenyltransferase activity |
GO:0008318 |
49 |
| Protein transmembrane transporter activity |
GO:0008320 |
53 |
| Ral guanyl-nucleotide exchange factor activity |
GO:0008321 |
19 |
| Cation transmembrane transporter activity |
GO:0008324 |
1915 |
| Methyl-CpG binding |
GO:0008327 |
968 |
| Pattern recognition receptor activity |
GO:0008329 |
854 |
| Protein tyrosine/threonine phosphatase activity |
GO:0008330 |
1424 |
| High voltage-gated calcium channel activity |
GO:0008331 |
491 |
| Low voltage-gated calcium channel activity |
GO:0008332 |
12 |
| MAP kinase kinase kinase kinase activity |
GO:0008349 |
375 |
| RNA polymerase II carboxy-terminal domain kinase activity |
GO:0008353 |
1512 |
| Sialyltransferase activity |
GO:0008373 |
1273 |
| O-acyltransferase activity |
GO:0008374 |
1 |
| Acetylglucosaminyltransferase activity |
GO:0008375 |
34 |
| Acetylgalactosaminyltransferase activity |
GO:0008376 |
19 |
| Galactosyltransferase activity |
GO:0008378 |
919 |
| Thioredoxin peroxidase activity |
GO:0008379 |
41 |
| IkappaB kinase activity |
GO:0008384 |
21 |
| Cholesterol monooxygenase (side-chain-cleaving) activity |
GO:0008386 |
2 |
| Coumarin 7-hydroxylase activity |
GO:0008389 |
3 |
| Arachidonic acid epoxygenase activity |
GO:0008392 |
938 |
| Steroid hydroxylase activity |
GO:0008395 |
1690 |
| Sterol 12-alpha-hydroxylase activity |
GO:0008397 |
675 |
| Sterol 14-demethylase activity |
GO:0008398 |
656 |
| Retinoic acid 4-hydroxylase activity |
GO:0008401 |
5 |
| 25-hydroxycholecalciferol-24-hydroxylase activity |
GO:0008403 |
8 |
| 3'-5' exonuclease activity |
GO:0008408 |
1069 |
| 5'-3' exonuclease activity |
GO:0008409 |
1368 |
| CoA-transferase activity |
GO:0008410 |
1 |
| 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
GO:0008413 |
468 |
| Fucosyltransferase activity |
GO:0008417 |
3178 |
| RNA lariat debranching enzyme activity |
GO:0008419 |
595 |
| CTD phosphatase activity |
GO:0008420 |
4 |
| Beta-glucosidase activity |
GO:0008422 |
10 |
| Glycoprotein 6-alpha-L-fucosyltransferase activity |
GO:0008424 |
28 |
| 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity |
GO:0008425 |
4 |
| Protein kinase C inhibitor activity |
GO:0008426 |
4 |
| Calcium-dependent protein kinase inhibitor activity |
GO:0008427 |
2 |
| Ribonuclease inhibitor activity |
GO:0008428 |
2 |
| Phosphatidylethanolamine binding |
GO:0008429 |
1257 |
| Selenium binding |
GO:0008430 |
405 |
| Vitamin E binding |
GO:0008431 |
353 |
| JUN kinase binding |
GO:0008432 |
1174 |
| Vitamin D3 receptor activity |
GO:0008434 |
415 |
| Thyrotropin-releasing hormone activity |
GO:0008437 |
1 |
| Inositol-1,4,5-trisphosphate 3-kinase activity |
GO:0008440 |
28 |
| 3'(2'),5'-bisphosphate nucleotidase activity |
GO:0008441 |
730 |
| GDP-mannose 4,6-dehydratase activity |
GO:0008446 |
1 |
| N-acetylglucosamine-6-phosphate deacetylase activity |
GO:0008448 |
1 |
| N-acetylglucosamine-6-sulfatase activity |
GO:0008449 |
14 |
| Alanine-glyoxylate transaminase activity |
GO:0008453 |
2 |
| Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity |
GO:0008454 |
1116 |
| Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity |
GO:0008455 |
4 |
| Alpha-N-acetylgalactosaminidase activity |
GO:0008456 |
4 |
| Carnitine O-octanoyltransferase activity |
GO:0008458 |
158 |
| Chondroitin 6-sulfotransferase activity |
GO:0008459 |
3 |
| DTDP-glucose 4,6-dehydratase activity |
GO:0008460 |
1 |
| Glycogenin glucosyltransferase activity |
GO:0008466 |
129 |
| [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity |
GO:0008467 |
11 |
| Histone-arginine N-methyltransferase activity |
GO:0008469 |
216 |
| Isovaleryl-CoA dehydrogenase activity |
GO:0008470 |
1362 |
| Palmitoyl-(protein) hydrolase activity |
GO:0008474 |
35 |
| Procollagen-lysine 5-dioxygenase activity |
GO:0008475 |
14 |
| Protein-tyrosine sulfotransferase activity |
GO:0008476 |
5 |
| Pyridoxal kinase activity |
GO:0008478 |
617 |
| Queuine tRNA-ribosyltransferase activity |
GO:0008479 |
1 |
| Sarcosine dehydrogenase activity |
GO:0008480 |
2 |
| Sphinganine kinase activity |
GO:0008481 |
2 |
| Sulfite oxidase activity |
GO:0008482 |
14 |
| Transaminase activity |
GO:0008483 |
13 |
| Sulfuric ester hydrolase activity |
GO:0008484 |
2013 |
| Diphosphoinositol-polyphosphate diphosphatase activity |
GO:0008486 |
52 |
| Gamma-glutamyl carboxylase activity |
GO:0008488 |
1369 |
| UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity |
GO:0008489 |
44 |
| Translation activator activity |
GO:0008494 |
518 |
| Protoheme IX farnesyltransferase activity |
GO:0008495 |
2 |
| UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity |
GO:0008499 |
205 |
| Melatonin receptor activity |
GO:0008502 |
7 |
| Benzodiazepine receptor activity |
GO:0008503 |
69 |
| Monoamine transmembrane transporter activity |
GO:0008504 |
1053 |
| Sodium:iodide symporter activity |
GO:0008507 |
923 |
| Bile acid:sodium symporter activity |
GO:0008508 |
14 |
| Anion transmembrane transporter activity |
GO:0008509 |
533 |
| Sodium:bicarbonate symporter activity |
GO:0008510 |
800 |
| Sodium:potassium:chloride symporter activity |
GO:0008511 |
578 |
| Secondary active organic cation transmembrane transporter activity |
GO:0008513 |
3 |
| Organic anion transmembrane transporter activity |
GO:0008514 |
47 |
| Folic acid transporter activity |
GO:0008517 |
1097 |
| Ammonium transmembrane transporter activity |
GO:0008519 |
1310 |
| L-ascorbate:sodium symporter activity |
GO:0008520 |
24 |
| Sodium-dependent multivitamin transmembrane transporter activity |
GO:0008523 |
21 |
| Phosphatidylcholine transporter activity |
GO:0008525 |
6 |
| Phosphatidylinositol transporter activity |
GO:0008526 |
41 |
| Taste receptor activity |
GO:0008527 |
631 |
| G-protein coupled peptide receptor activity |
GO:0008528 |
690 |
| Riboflavin kinase activity |
GO:0008531 |
220 |
| N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity |
GO:0008532 |
1 |
| Oxidized purine base lesion DNA N-glycosylase activity |
GO:0008534 |
10 |
| Ran GTPase binding |
GO:0008536 |
1355 |
| JUN kinase kinase activity |
GO:0008545 |
11 |
| Hydrogen-exporting ATPase activity, phosphorylative mechanism |
GO:0008553 |
352 |
| Sodium-exporting ATPase activity, phosphorylative mechanism |
GO:0008554 |
3 |
| Chloride-transporting ATPase activity |
GO:0008555 |
1161 |
| Xenobiotic-transporting ATPase activity |
GO:0008559 |
7 |
| Protein transporter activity |
GO:0008565 |
4699 |
| Microtubule-severing ATPase activity |
GO:0008568 |
1238 |
| Minus-end-directed microtubule motor activity |
GO:0008569 |
8 |
| Plus-end-directed microtubule motor activity |
GO:0008574 |
3848 |
| JUN kinase phosphatase activity |
GO:0008579 |
1424 |
| Protein phosphatase type 1 regulator activity |
GO:0008599 |
594 |
| Protein phosphatase type 2A regulator activity |
GO:0008601 |
1041 |
| CAMP-dependent protein kinase regulator activity |
GO:0008603 |
30 |
| Phosphorylase kinase regulator activity |
GO:0008607 |
540 |
| Alkylglycerone-phosphate synthase activity |
GO:0008609 |
14 |
| Small protein activating enzyme activity |
GO:0008641 |
11 |
| RRNA (uridine-2'-O-)-methyltransferase activity |
GO:0008650 |
90 |
| Cysteine-type endopeptidase activator activity involved in apoptotic process |
GO:0008656 |
2448 |
| 2'-phosphotransferase activity |
GO:0008665 |
1 |
| 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity |
GO:0008667 |
133 |
| 2,4-dienoyl-CoA reductase (NADPH) activity |
GO:0008670 |
475 |
| 3-demethylubiquinone-9 3-O-methyltransferase activity |
GO:0008689 |
4 |
| Methionine synthase activity |
GO:0008705 |
586 |
| D-serine ammonia-lyase activity |
GO:0008721 |
1 |
| L-allo-threonine aldolase activity |
GO:0008732 |
9 |
| N-acetylmuramoyl-L-alanine amidase activity |
GO:0008745 |
4 |
| NAD(P)+ transhydrogenase activity |
GO:0008746 |
5 |
| N-acetylneuraminate lyase activity |
GO:0008747 |
3 |
| NAD(P)+ transhydrogenase (AB-specific) activity |
GO:0008750 |
5 |
| NADPH dehydrogenase (quinone) activity |
GO:0008753 |
2 |
| S-adenosylmethionine-dependent methyltransferase activity |
GO:0008757 |
1621 |
| UDP-N-acetylglucosamine 2-epimerase activity |
GO:0008761 |
1948 |
| UDP-N-acetylmuramate dehydrogenase activity |
GO:0008762 |
272 |
| UDP-sugar diphosphatase activity |
GO:0008768 |
1 |
| Agmatinase activity |
GO:0008783 |
1903 |
| Arsenate reductase (glutaredoxin) activity |
GO:0008794 |
1 |
| Beta-aspartyl-peptidase activity |
GO:0008798 |
77 |
| Betaine-aldehyde dehydrogenase activity |
GO:0008802 |
519 |
| Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity |
GO:0008803 |
4 |
| Choline dehydrogenase activity |
GO:0008812 |
396 |
| Cob(I)yrinic acid a,c-diamide adenosyltransferase activity |
GO:0008817 |
426 |
| Crossover junction endodeoxyribonuclease activity |
GO:0008821 |
366 |
| Cupric reductase activity |
GO:0008823 |
1207 |
| DTDP-4-dehydrorhamnose reductase activity |
GO:0008831 |
2 |
| Endochitinase activity |
GO:0008843 |
2 |
| Exodeoxyribonuclease III activity |
GO:0008853 |
6 |
| Exoribonuclease II activity |
GO:0008859 |
2 |
| Fructokinase activity |
GO:0008865 |
274 |
| Glycerate kinase activity |
GO:0008887 |
9 |
| Glycerophosphodiester phosphodiesterase activity |
GO:0008889 |
2035 |
| Glycine C-acetyltransferase activity |
GO:0008890 |
340 |
| Glycolate oxidase activity |
GO:0008891 |
2 |
| Guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity |
GO:0008894 |
3 |
| Homocysteine S-methyltransferase activity |
GO:0008898 |
1562 |
| Hydrogen:potassium-exchanging ATPase activity |
GO:0008900 |
10 |
| Hydroxypyruvate isomerase activity |
GO:0008903 |
1 |
| Integrase activity |
GO:0008907 |
5 |
| Inositol monophosphate 1-phosphatase activity |
GO:0008934 |
969 |
| Nitric oxide dioxygenase activity |
GO:0008941 |
4 |
| Oxaloacetate decarboxylase activity |
GO:0008948 |
933 |
| Phosphatidylglycerophosphatase activity |
GO:0008962 |
3 |
| Phospho-N-acetylmuramoyl-pentapeptide-transferase activity |
GO:0008963 |
1 |
| Phosphohistidine phosphatase activity |
GO:0008969 |
5 |
| Phosphatidylcholine 1-acylhydrolase activity |
GO:0008970 |
6 |
| Phosphopentomutase activity |
GO:0008973 |
2 |
| Ribonuclease E activity |
GO:0008995 |
1 |
| Selenocysteine lyase activity |
GO:0009000 |
1 |
| DNA-methyltransferase activity |
GO:0009008 |
64 |
| Succinate-semialdehyde dehydrogenase [NAD(P)+] activity |
GO:0009013 |
708 |
| Uridylate kinase activity |
GO:0009041 |
2 |
| Electron carrier activity |
GO:0009055 |
3732 |
| Biotin binding |
GO:0009374 |
846 |
| Four-way junction helicase activity |
GO:0009378 |
207 |
| N-acylmannosamine kinase activity |
GO:0009384 |
1948 |
| Low affinity phosphate transmembrane transporter activity |
GO:0009673 |
3 |
| Photoreceptor activity |
GO:0009881 |
24 |
| Blue light photoreceptor activity |
GO:0009882 |
10 |
| Sterol 5-alpha reductase activity |
GO:0009917 |
3 |
| Fatty acid elongase activity |
GO:0009922 |
10 |
| Pseudouridine synthase activity |
GO:0009982 |
60 |
| FMN binding |
GO:0010181 |
2269 |
| Phosphatidylinositol-5-phosphate binding |
GO:0010314 |
2093 |
| Double-stranded methylated DNA binding |
GO:0010385 |
18 |
| Methyl-CpNpG binding |
GO:0010428 |
10 |
| Nerve growth factor receptor activity |
GO:0010465 |
5 |
| H3 histone acetyltransferase activity |
GO:0010484 |
766 |
| H4 histone acetyltransferase activity |
GO:0010485 |
1357 |
| Telomerase inhibitor activity |
GO:0010521 |
4 |
| Metalloenzyme activator activity |
GO:0010577 |
4 |
| Serum response element binding |
GO:0010736 |
10 |
| Recombination hotspot binding |
GO:0010844 |
2 |
| Adenylate cyclase inhibitor activity |
GO:0010855 |
6 |
| Thyroid hormone receptor activator activity |
GO:0010861 |
2 |
| Anaphase-promoting complex binding |
GO:0010997 |
2006 |
| [heparan sulfate]-glucosamine N-sulfotransferase activity |
GO:0015016 |
680 |
| Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity |
GO:0015018 |
4 |
| Heparan-alpha-glucosaminide N-acetyltransferase activity |
GO:0015019 |
7 |
| Glucuronosyltransferase activity |
GO:0015020 |
441 |
| Coreceptor activity |
GO:0015026 |
565 |
| Protein disulfide oxidoreductase activity |
GO:0015035 |
469 |
| Disulfide oxidoreductase activity |
GO:0015036 |
390 |
| Glutathione disulfide oxidoreductase activity |
GO:0015038 |
4 |
| NADPH-adrenodoxin reductase activity |
GO:0015039 |
2 |
| Beta3-adrenergic receptor activity |
GO:0015052 |
13 |
| Gastrin receptor activity |
GO:0015054 |
2 |
| Secretin receptor activity |
GO:0015055 |
3 |
| Corticotrophin-releasing factor receptor activity |
GO:0015056 |
27 |
| Thrombin receptor activity |
GO:0015057 |
2136 |
| Amidinotransferase activity |
GO:0015067 |
1 |
| Glycine amidinotransferase activity |
GO:0015068 |
1 |
| Ion transmembrane transporter activity |
GO:0015075 |
14 |
| Monovalent inorganic cation transmembrane transporter activity |
GO:0015077 |
1438 |
| Hydrogen ion transmembrane transporter activity |
GO:0015078 |
2849 |
| Potassium ion transmembrane transporter activity |
GO:0015079 |
1704 |
| Sodium ion transmembrane transporter activity |
GO:0015081 |
18 |
| Calcium ion transmembrane transporter activity |
GO:0015085 |
614 |
| Cadmium ion transmembrane transporter activity |
GO:0015086 |
591 |
| Cobalt ion transmembrane transporter activity |
GO:0015087 |
591 |
| Copper uptake transmembrane transporter activity |
GO:0015088 |
1046 |
| Ferrous iron transmembrane transporter activity |
GO:0015093 |
648 |
| Lead ion transmembrane transporter activity |
GO:0015094 |
591 |
| Magnesium ion transmembrane transporter activity |
GO:0015095 |
1338 |
| Nickel cation transmembrane transporter activity |
GO:0015099 |
591 |
| Vanadium ion transmembrane transporter activity |
GO:0015100 |
591 |
| Organic cation transmembrane transporter activity |
GO:0015101 |
13 |
| Bicarbonate transmembrane transporter activity |
GO:0015106 |
537 |
| Chloride transmembrane transporter activity |
GO:0015108 |
1164 |
| Iodide transmembrane transporter activity |
GO:0015111 |
1752 |
| Nitrate transmembrane transporter activity |
GO:0015112 |
787 |
| Sulfate transmembrane transporter activity |
GO:0015116 |
1249 |
| Bile acid transmembrane transporter activity |
GO:0015125 |
8 |
| Canalicular bile acid transmembrane transporter activity |
GO:0015126 |
3 |
| Lactate transmembrane transporter activity |
GO:0015129 |
803 |
| Mevalonate transmembrane transporter activity |
GO:0015130 |
5 |
| Sialic acid transmembrane transporter activity |
GO:0015136 |
794 |
| Citrate transmembrane transporter activity |
GO:0015137 |
14 |
| Succinate transmembrane transporter activity |
GO:0015141 |
8 |
| Urate transmembrane transporter activity |
GO:0015143 |
3 |
| Hexose transmembrane transporter activity |
GO:0015149 |
2 |
| Glucose-6-phosphate transmembrane transporter activity |
GO:0015152 |
4 |
| Polyol transmembrane transporter activity |
GO:0015166 |
2 |
| Glycerol transmembrane transporter activity |
GO:0015168 |
12 |
| Amino acid transmembrane transporter activity |
GO:0015171 |
2329 |
| Basic amino acid transmembrane transporter activity |
GO:0015174 |
787 |
| Neutral amino acid transmembrane transporter activity |
GO:0015175 |
253 |
| L-amino acid transmembrane transporter activity |
GO:0015179 |
1598 |
| L-alanine transmembrane transporter activity |
GO:0015180 |
1081 |
| Arginine transmembrane transporter activity |
GO:0015181 |
608 |
| L-asparagine transmembrane transporter activity |
GO:0015182 |
11 |
| L-aspartate transmembrane transporter activity |
GO:0015183 |
224 |
| L-cystine transmembrane transporter activity |
GO:0015184 |
617 |
| L-glutamine transmembrane transporter activity |
GO:0015186 |
49 |
| Glycine transmembrane transporter activity |
GO:0015187 |
1068 |
| L-lysine transmembrane transporter activity |
GO:0015189 |
784 |
| L-proline transmembrane transporter activity |
GO:0015193 |
1070 |
| L-serine transmembrane transporter activity |
GO:0015194 |
838 |
| L-threonine transmembrane transporter activity |
GO:0015195 |
12 |
| Peptide transporter activity |
GO:0015197 |
65 |
| Oligopeptide transporter activity |
GO:0015198 |
725 |
| Urea transmembrane transporter activity |
GO:0015204 |
1541 |
| Nucleobase transmembrane transporter activity |
GO:0015205 |
24 |
| Adenine transmembrane transporter activity |
GO:0015207 |
315 |
| Purine nucleoside transmembrane transporter activity |
GO:0015211 |
760 |
| Purine nucleotide transmembrane transporter activity |
GO:0015216 |
4 |
| ADP transmembrane transporter activity |
GO:0015217 |
2 |
| Choline transmembrane transporter activity |
GO:0015220 |
3 |
| Serotonin transmembrane transporter activity |
GO:0015222 |
1037 |
| Carnitine transporter activity |
GO:0015226 |
6 |
| Acyl carnitine transporter activity |
GO:0015227 |
1 |
| Coenzyme A transmembrane transporter activity |
GO:0015228 |
2 |
| L-ascorbic acid transporter activity |
GO:0015229 |
24 |
| FAD transmembrane transporter activity |
GO:0015230 |
2 |
| Heme transporter activity |
GO:0015232 |
897 |
| Drug transmembrane transporter activity |
GO:0015238 |
9 |
| Fatty acid transporter activity |
GO:0015245 |
1 |
| Sterol transporter activity |
GO:0015248 |
5 |
| Water channel activity |
GO:0015250 |
964 |
| Hydrogen ion channel activity |
GO:0015252 |
12 |
| Glycerol channel activity |
GO:0015254 |
814 |
| Urea channel activity |
GO:0015265 |
441 |
| Protein channel activity |
GO:0015266 |
10 |
| Channel activity |
GO:0015267 |
757 |
| Calcium-activated potassium channel activity |
GO:0015269 |
64 |
| Outward rectifier potassium channel activity |
GO:0015271 |
13 |
| ATP-activated inward rectifier potassium channel activity |
GO:0015272 |
859 |
| Ligand-gated ion channel activity |
GO:0015276 |
1671 |
| Kainate selective glutamate receptor activity |
GO:0015277 |
34 |
| Calcium-release channel activity |
GO:0015278 |
974 |
| Store-operated calcium channel activity |
GO:0015279 |
34 |
| Ligand-gated sodium channel activity |
GO:0015280 |
112 |
| Porin activity |
GO:0015288 |
15 |
| Symporter activity |
GO:0015293 |
1167 |
| Solute:hydrogen symporter activity |
GO:0015295 |
591 |
| Antiporter activity |
GO:0015297 |
1048 |
| Solute:hydrogen antiporter activity |
GO:0015299 |
21 |
| Anion:anion antiporter activity |
GO:0015301 |
810 |
| Sodium:inorganic phosphate symporter activity |
GO:0015319 |
2 |
| Phosphate ion carrier activity |
GO:0015320 |
1 |
| Sodium-dependent phosphate transmembrane transporter activity |
GO:0015321 |
104 |
| Cystine:glutamate antiporter activity |
GO:0015327 |
1055 |
| Peptide:hydrogen symporter activity |
GO:0015333 |
1512 |
| High affinity oligopeptide transporter activity |
GO:0015334 |
787 |
| Sodium-independent organic anion transmembrane transporter activity |
GO:0015347 |
441 |
| Methotrexate transporter activity |
GO:0015350 |
198 |
| Secondary active monocarboxylate transmembrane transporter activity |
GO:0015355 |
803 |
| Low affinity sodium:dicarboxylate symporter activity |
GO:0015361 |
5 |
| High affinity sodium:dicarboxylate symporter activity |
GO:0015362 |
8 |
| Glycine:sodium symporter activity |
GO:0015375 |
9 |
| Cation:chloride symporter activity |
GO:0015377 |
865 |
| Sodium:chloride symporter activity |
GO:0015378 |
388 |
| Potassium:chloride symporter activity |
GO:0015379 |
1689 |
| Sodium:sulfate symporter activity |
GO:0015382 |
350 |
| Sodium:hydrogen antiporter activity |
GO:0015385 |
82 |
| Potassium:hydrogen antiporter activity |
GO:0015386 |
10 |
| Pyrimidine- and adenine-specific:sodium symporter activity |
GO:0015389 |
6 |
| Purine-specific nucleoside:sodium symporter activity |
GO:0015390 |
6 |
| Thiamine uptake transmembrane transporter activity |
GO:0015403 |
662 |
| Manganese-transporting ATPase activity |
GO:0015410 |
5 |
| Bile acid-exporting ATPase activity |
GO:0015432 |
3 |
| Peptide antigen-transporting ATPase activity |
GO:0015433 |
1379 |
| Heme-transporting ATPase activity |
GO:0015439 |
7 |
| Peptide-transporting ATPase activity |
GO:0015440 |
5 |
| P-P-bond-hydrolysis-driven protein transmembrane transporter activity |
GO:0015450 |
712 |
| Potassium channel regulator activity |
GO:0015459 |
2351 |
| Acetylcholine receptor activity |
GO:0015464 |
1906 |
| G-protein activated inward rectifier potassium channel activity |
GO:0015467 |
1654 |
| Cholesterol binding |
GO:0015485 |
2574 |
| Gamma-aminobutyric acid:hydrogen symporter activity |
GO:0015495 |
1 |
| Formate transmembrane transporter activity |
GO:0015499 |
1 |
| Efflux transmembrane transporter activity |
GO:0015562 |
1388 |
| DNA translocase activity |
GO:0015616 |
610 |
| Tubulin binding |
GO:0015631 |
3064 |
| Zinc transporting ATPase activity |
GO:0015633 |
14 |
| Short-chain fatty acid uptake transporter activity |
GO:0015636 |
425 |
| Toxin binding |
GO:0015643 |
2057 |
| Fatty acid ligase activity |
GO:0015645 |
3 |
| Quaternary ammonium group transmembrane transporter activity |
GO:0015651 |
8 |
| Formate uptake transmembrane transporter activity |
GO:0015659 |
1 |
| Formate efflux transmembrane transporter activity |
GO:0015660 |
1 |
| Mannosidase activity |
GO:0015923 |
606 |
| Phospholipase activator activity |
GO:0016004 |
1883 |
| Phospholipase A2 activator activity |
GO:0016005 |
5 |
| Morphogen activity |
GO:0016015 |
938 |
| Cyclosporin A binding |
GO:0016018 |
844 |
| Peptidoglycan receptor activity |
GO:0016019 |
5 |
| Translation release factor activity, codon specific |
GO:0016149 |
10 |
| Nickel cation binding |
GO:0016151 |
593 |
| Urocanate hydratase activity |
GO:0016153 |
6 |
| Lipoxygenase activity |
GO:0016165 |
68 |
| Glial cell-derived neurotrophic factor receptor activity |
GO:0016167 |
31 |
| NAD(P)H oxidase activity |
GO:0016174 |
1095 |
| Superoxide-generating NADPH oxidase activity |
GO:0016175 |
343 |
| Superoxide-generating NADPH oxidase activator activity |
GO:0016176 |
13 |
| Catechol O-methyltransferase activity |
GO:0016206 |
1487 |
| AMP binding |
GO:0016208 |
1187 |
| Antioxidant activity |
GO:0016209 |
685 |
| Kynurenine-oxoglutarate transaminase activity |
GO:0016212 |
7 |
| Steroid dehydrogenase activity |
GO:0016229 |
4 |
| Sphingomyelin phosphodiesterase activator activity |
GO:0016230 |
3 |
| Beta-N-acetylglucosaminidase activity |
GO:0016231 |
3 |
| HNK-1 sulfotransferase activity |
GO:0016232 |
2 |
| Channel regulator activity |
GO:0016247 |
4 |
| Channel inhibitor activity |
GO:0016248 |
4 |
| N-sulfoglucosamine sulfohydrolase activity |
GO:0016250 |
3 |
| Protein N-acetylglucosaminyltransferase activity |
GO:0016262 |
521 |
| Protein-arginine N-methyltransferase activity |
GO:0016274 |
18 |
| [cytochrome c]-arginine N-methyltransferase activity |
GO:0016275 |
1 |
| [myelin basic protein]-arginine N-methyltransferase activity |
GO:0016277 |
194 |
| Protein-lysine N-methyltransferase activity |
GO:0016279 |
1136 |
| Small conductance calcium-activated potassium channel activity |
GO:0016286 |
1465 |
| Palmitoyl-CoA hydrolase activity |
GO:0016290 |
1102 |
| Myristoyl-[acyl-carrier-protein] hydrolase activity |
GO:0016295 |
675 |
| Palmitoyl-[acyl-carrier-protein] hydrolase activity |
GO:0016296 |
675 |
| Lipase activity |
GO:0016298 |
18 |
| TRNA (uracil) methyltransferase activity |
GO:0016300 |
5 |
| Kinase activity |
GO:0016301 |
2653 |
| 1-phosphatidylinositol-3-kinase activity |
GO:0016303 |
2954 |
| Phosphatidylinositol phosphate kinase activity |
GO:0016307 |
20 |
| 1-phosphatidylinositol-4-phosphate 5-kinase activity |
GO:0016308 |
511 |
| 1-phosphatidylinositol-5-phosphate 4-kinase activity |
GO:0016309 |
11 |
| Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity |
GO:0016314 |
7 |
| Phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity |
GO:0016316 |
9 |
| Activin receptor activity, type I |
GO:0016361 |
484 |
| Activin receptor activity, type II |
GO:0016362 |
858 |
| Palmitoyl-CoA oxidase activity |
GO:0016401 |
1602 |
| Pristanoyl-CoA oxidase activity |
GO:0016402 |
5 |
| Dimethylargininase activity |
GO:0016403 |
2 |
| 15-hydroxyprostaglandin dehydrogenase (NAD+) activity |
GO:0016404 |
90 |
| Acetyltransferase activity |
GO:0016407 |
723 |
| Palmitoyltransferase activity |
GO:0016409 |
1993 |
| N-acyltransferase activity |
GO:0016410 |
3 |
| MRNA (2'-O-methyladenosine-N6-)-methyltransferase activity |
GO:0016422 |
6 |
| TRNA (cytosine) methyltransferase activity |
GO:0016427 |
1123 |
| TRNA (cytosine-5-)-methyltransferase activity |
GO:0016428 |
3 |
| Pyrophosphatase activity |
GO:0016462 |
29 |
| Oxidoreductase activity |
GO:0016491 |
5402 |
| G-protein coupled neurotensin receptor activity |
GO:0016492 |
11 |
| C-C chemokine receptor activity |
GO:0016493 |
1608 |
| C-X-C chemokine receptor activity |
GO:0016494 |
1173 |
| C-X3-C chemokine receptor activity |
GO:0016495 |
3 |
| Substance P receptor activity |
GO:0016496 |
10 |
| Substance K receptor activity |
GO:0016497 |
9 |
| Protein-hormone receptor activity |
GO:0016500 |
4 |
| Pheromone receptor activity |
GO:0016503 |
2 |
| Peptidase activator activity |
GO:0016504 |
43 |
| Apoptotic protease activator activity |
GO:0016505 |
67 |
| Long-chain-enoyl-CoA hydratase activity |
GO:0016508 |
6 |
| Long-chain-3-hydroxyacyl-CoA dehydrogenase activity |
GO:0016509 |
6 |
| Interleukin-13 receptor activity |
GO:0016515 |
419 |
| Interleukin-12 receptor activity |
GO:0016517 |
937 |
| Gastric inhibitory peptide receptor activity |
GO:0016519 |
1 |
| Growth hormone-releasing hormone receptor activity |
GO:0016520 |
12 |
| Pituitary adenylate cyclase activating polypeptide activity |
GO:0016521 |
4 |
| Latrotoxin receptor activity |
GO:0016524 |
8 |
| Superoxide dismutase copper chaperone activity |
GO:0016532 |
438 |
| Cyclin-dependent protein kinase 5 activator activity |
GO:0016534 |
4 |
| Cyclin-dependent protein kinase regulator activity |
GO:0016538 |
380 |
| Glycine binding |
GO:0016594 |
1898 |
| Glutamate binding |
GO:0016595 |
1984 |
| Amino acid binding |
GO:0016597 |
1872 |
| Glutaminyl-peptide cyclotransferase activity |
GO:0016603 |
1338 |
| Growth hormone-releasing hormone activity |
GO:0016608 |
2 |
| Oxidoreductase activity, acting on CH-OH group of donors |
GO:0016614 |
396 |
| Malate dehydrogenase activity |
GO:0016615 |
5 |
| Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
GO:0016616 |
745 |
| Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
GO:0016620 |
1774 |
| Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
GO:0016624 |
229 |
| Oxidoreductase activity, acting on the CH-CH group of donors |
GO:0016627 |
2085 |
| Oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
GO:0016628 |
149 |
| Oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor |
GO:0016641 |
6 |
| Oxidoreductase activity, acting on NADH or NADPH |
GO:0016651 |
1219 |
| Oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor |
GO:0016653 |
3 |
| Oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor |
GO:0016655 |
9 |
| Oxidoreductase activity, acting on a sulfur group of donors |
GO:0016667 |
8 |
| Oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor |
GO:0016668 |
1144 |
| Oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor |
GO:0016670 |
1164 |
| Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor |
GO:0016671 |
94 |
| Oxidoreductase activity, acting on diphenols and related substances as donors |
GO:0016679 |
1 |
| Oxidoreductase activity, acting on peroxide as acceptor |
GO:0016684 |
4 |
| Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
GO:0016702 |
183 |
| Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
GO:0016705 |
3633 |
| Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors |
GO:0016706 |
2249 |
| Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen |
GO:0016709 |
940 |
| Flavonoid 3'-monooxygenase activity |
GO:0016711 |
1 |
| Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
GO:0016712 |
2318 |
| Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen |
GO:0016714 |
9 |
| Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen |
GO:0016715 |
18 |
| Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen |
GO:0016716 |
1 |
| Oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
GO:0016717 |
2 |
| Oxidoreductase activity, oxidizing metal ions |
GO:0016722 |
4 |
| Transferase activity |
GO:0016740 |
2968 |
| Hydroxymethyl-, formyl- and related transferase activity |
GO:0016742 |
1634 |
| Carboxyl- or carbamoyltransferase activity |
GO:0016743 |
6 |
| Transferase activity, transferring acyl groups |
GO:0016746 |
3457 |
| Transferase activity, transferring acyl groups other than amino-acyl groups |
GO:0016747 |
1092 |
| Transferase activity, transferring glycosyl groups |
GO:0016757 |
3376 |
| Transferase activity, transferring hexosyl groups |
GO:0016758 |
1802 |
| Transferase activity, transferring pentosyl groups |
GO:0016763 |
154 |
| Spermine synthase activity |
GO:0016768 |
2 |
| Transferase activity, transferring phosphorus-containing groups |
GO:0016772 |
1239 |
| Phosphotransferase activity, alcohol group as acceptor |
GO:0016773 |
3554 |
| Nucleotidyltransferase activity |
GO:0016779 |
1187 |
| Phosphotransferase activity, for other substituted phosphate groups |
GO:0016780 |
522 |
| Sulfurtransferase activity |
GO:0016783 |
7 |
| 3-mercaptopyruvate sulfurtransferase activity |
GO:0016784 |
1 |
| Transferase activity, transferring selenium-containing groups |
GO:0016785 |
4 |
| Hydrolase activity |
GO:0016787 |
5016 |
| Hydrolase activity, acting on ester bonds |
GO:0016788 |
1021 |
| Thiolester hydrolase activity |
GO:0016790 |
37 |
| Phosphatase activity |
GO:0016791 |
2852 |
| Hydrolase activity, acting on glycosyl bonds |
GO:0016798 |
1167 |
| Hydrolase activity, hydrolyzing N-glycosyl compounds |
GO:0016799 |
762 |
| Dipeptidase activity |
GO:0016805 |
262 |
| Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
GO:0016810 |
20 |
| Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
GO:0016811 |
316 |
| Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
GO:0016812 |
15 |
| Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
GO:0016813 |
2 |
| Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines |
GO:0016814 |
1810 |
| Hydrolase activity, acting on acid anhydrides |
GO:0016817 |
502 |
| Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
GO:0016818 |
211 |
| Hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
GO:0016820 |
8 |
| Lyase activity |
GO:0016829 |
1710 |
| Carboxy-lyase activity |
GO:0016831 |
1381 |
| Ammonia-lyase activity |
GO:0016841 |
4 |
| Carbon-sulfur lyase activity |
GO:0016846 |
301 |
| Phosphorus-oxygen lyase activity |
GO:0016849 |
75 |
| Isomerase activity |
GO:0016853 |
1882 |
| Racemase and epimerase activity |
GO:0016854 |
1 |
| Racemase and epimerase activity, acting on carbohydrates and derivatives |
GO:0016857 |
53 |
| Intramolecular transferase activity |
GO:0016866 |
1415 |
| Intramolecular transferase activity, phosphotransferases |
GO:0016868 |
10 |
| Ligase activity |
GO:0016874 |
5904 |
| Acid-thiol ligase activity |
GO:0016878 |
6 |
| Acid-amino acid ligase activity |
GO:0016881 |
2895 |
| Carbon-nitrogen ligase activity, with glutamine as amido-N-donor |
GO:0016884 |
782 |
| ATPase activity |
GO:0016887 |
5098 |
| Endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
GO:0016888 |
1424 |
| Endoribonuclease activity, producing 5'-phosphomonoesters |
GO:0016891 |
5 |
| Exoribonuclease activity, producing 5'-phosphomonoesters |
GO:0016896 |
1240 |
| Oxidoreductase activity, acting on the aldehyde or oxo group of donors |
GO:0016903 |
243 |
| G-protein coupled acetylcholine receptor activity |
GO:0016907 |
142 |
| GABA receptor activity |
GO:0016917 |
5 |
| Retinal binding |
GO:0016918 |
555 |
| Pyroglutamyl-peptidase activity |
GO:0016920 |
2040 |
| Ligand-dependent nuclear receptor binding |
GO:0016922 |
1229 |
| SUMO-specific protease activity |
GO:0016929 |
22 |
| Extracellular-glycine-gated ion channel activity |
GO:0016933 |
2 |
| Extracellular-glycine-gated chloride channel activity |
GO:0016934 |
18 |
| Galactoside binding |
GO:0016936 |
3 |
| Natriuretic peptide receptor activity |
GO:0016941 |
5 |
| Flavin-linked sulfhydryl oxidase activity |
GO:0016971 |
7 |
| Thiol oxidase activity |
GO:0016972 |
4 |
| Lipoate synthase activity |
GO:0016992 |
735 |
| Activin-activated receptor activity |
GO:0017002 |
14 |
| 3'-tyrosyl-DNA phosphodiesterase activity |
GO:0017005 |
216 |
| Ras GTPase binding |
GO:0017016 |
641 |
| MAP kinase tyrosine/serine/threonine phosphatase activity |
GO:0017017 |
195 |
| Myosin phosphatase regulator activity |
GO:0017020 |
4 |
| Myosin binding |
GO:0017022 |
2755 |
| TBP-class protein binding |
GO:0017025 |
1606 |
| Rap guanyl-nucleotide exchange factor activity |
GO:0017034 |
619 |
| Ceramidase activity |
GO:0017040 |
14 |
| Corticotropin-releasing hormone activity |
GO:0017045 |
2 |
| Peptide hormone binding |
GO:0017046 |
1815 |
| Rho GTPase binding |
GO:0017048 |
716 |
| GTP-Rho binding |
GO:0017049 |
2003 |
| D-erythro-sphingosine kinase activity |
GO:0017050 |
2 |
| Structural constituent of nuclear pore |
GO:0017056 |
759 |
| 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity |
GO:0017060 |
727 |
| S-methyl-5-thioadenosine phosphorylase activity |
GO:0017061 |
562 |
| Single-strand selective uracil DNA N-glycosylase activity |
GO:0017065 |
681 |
| SnRNA binding |
GO:0017069 |
4 |
| U6 snRNA binding |
GO:0017070 |
309 |
| Syntaxin-1 binding |
GO:0017075 |
1281 |
| Purine nucleotide binding |
GO:0017076 |
4 |
| Oxidative phosphorylation uncoupler activity |
GO:0017077 |
3 |
| Sodium channel regulator activity |
GO:0017080 |
3311 |
| Chloride channel regulator activity |
GO:0017081 |
1482 |
| Glycolipid transporter activity |
GO:0017089 |
17 |
| AU-rich element binding |
GO:0017091 |
74 |
| Heparan sulfate 6-O-sulfotransferase activity |
GO:0017095 |
12 |
| Sulfonylurea receptor binding |
GO:0017098 |
2 |
| 5'-flap endonuclease activity |
GO:0017108 |
16 |
| Nucleoside-diphosphatase activity |
GO:0017110 |
873 |
| Nucleoside-triphosphatase activity |
GO:0017111 |
875 |
| Rab guanyl-nucleotide exchange factor activity |
GO:0017112 |
2030 |
| Dihydropyrimidine dehydrogenase (NADP+) activity |
GO:0017113 |
19 |
| Single-stranded DNA-dependent ATP-dependent DNA helicase activity |
GO:0017116 |
2 |
| SH3 domain binding |
GO:0017124 |
4236 |
| Deoxycytidyl transferase activity |
GO:0017125 |
4 |
| Cholesterol transporter activity |
GO:0017127 |
30 |
| Phospholipid scramblase activity |
GO:0017128 |
682 |
| Triglyceride binding |
GO:0017129 |
4 |
| Poly(C) RNA binding |
GO:0017130 |
1 |
| Fibroblast growth factor binding |
GO:0017134 |
1556 |
| NAD-dependent histone deacetylase activity |
GO:0017136 |
6 |
| Rab GTPase binding |
GO:0017137 |
4321 |
| Wnt-protein binding |
GO:0017147 |
2135 |
| TRNA dihydrouridine synthase activity |
GO:0017150 |
1 |
| DEAD/H-box RNA helicase binding |
GO:0017151 |
6 |
| Sodium:dicarboxylate symporter activity |
GO:0017153 |
252 |
| Semaphorin receptor activity |
GO:0017154 |
78 |
| Pantetheine hydrolase activity |
GO:0017159 |
7 |
| Ral GTPase binding |
GO:0017160 |
5 |
| Aryl hydrocarbon receptor binding |
GO:0017162 |
82 |
| Vinculin binding |
GO:0017166 |
485 |
| 5-oxoprolinase (ATP-hydrolyzing) activity |
GO:0017168 |
2 |
| Serine hydrolase activity |
GO:0017171 |
15 |
| Phosphatidylinositol N-acetylglucosaminyltransferase activity |
GO:0017176 |
3 |
| Aspartate N-acetyltransferase activity |
GO:0017188 |
3 |
| Histone-lysine N-methyltransferase activity |
GO:0018024 |
1206 |
| Threonine racemase activity |
GO:0018114 |
1 |
| Biotin-protein ligase activity |
GO:0018271 |
523 |
| Alcohol dehydrogenase [NAD(P)+] activity |
GO:0018455 |
3 |
| Malonate-semialdehyde dehydrogenase (acetylating) activity |
GO:0018478 |
1616 |
| Benzaldehyde dehydrogenase (NAD+) activity |
GO:0018479 |
4 |
| Fluorene oxygenase activity |
GO:0018585 |
4 |
| (S)-limonene 6-monooxygenase activity |
GO:0018675 |
5 |
| (S)-limonene 7-monooxygenase activity |
GO:0018676 |
5 |
| Alkane 1-monooxygenase activity |
GO:0018685 |
9 |
| 3,4-dihydrocoumarin hydrolase activity |
GO:0018733 |
1 |
| Acetylpyruvate hydrolase activity |
GO:0018773 |
700 |
| Guanyl nucleotide binding |
GO:0019001 |
751 |
| GMP binding |
GO:0019002 |
449 |
| GDP binding |
GO:0019003 |
5038 |
| DNA N-glycosylase activity |
GO:0019104 |
688 |
| Benzaldehyde dehydrogenase activity |
GO:0019115 |
9 |
| Phenanthrene-9,10-epoxide hydrolase activity |
GO:0019119 |
370 |
| Deoxyhypusine monooxygenase activity |
GO:0019135 |
1 |
| ADP-sugar diphosphatase activity |
GO:0019144 |
19 |
| Aminobutyraldehyde dehydrogenase activity |
GO:0019145 |
2 |
| Protein-disulfide reductase (glutathione) activity |
GO:0019153 |
1 |
| Mannokinase activity |
GO:0019158 |
274 |
| Trans-2-enoyl-CoA reductase (NADPH) activity |
GO:0019166 |
738 |
| Glyoxalase III activity |
GO:0019172 |
1 |
| Nucleotide kinase activity |
GO:0019201 |
2 |
| Carbohydrate phosphatase activity |
GO:0019203 |
2 |
| Nucleobase-containing compound kinase activity |
GO:0019205 |
788 |
| Nucleoside kinase activity |
GO:0019206 |
123 |
| Kinase regulator activity |
GO:0019207 |
2 |
| Phosphatase regulator activity |
GO:0019208 |
32 |
| Kinase activator activity |
GO:0019209 |
14 |
| Kinase inhibitor activity |
GO:0019210 |
185 |
| Phosphatase activator activity |
GO:0019211 |
110 |
| Phosphatase inhibitor activity |
GO:0019212 |
23 |
| Deacetylase activity |
GO:0019213 |
1289 |
| Intermediate filament binding |
GO:0019215 |
440 |
| Centromeric DNA binding |
GO:0019237 |
878 |
| Deaminase activity |
GO:0019239 |
1104 |
| Oxalate transmembrane transporter activity |
GO:0019531 |
1 |
| Toxin transporter activity |
GO:0019534 |
15 |
| Protein-cysteine S-palmitoleyltransferase activity |
GO:0019706 |
2004 |
| IgE receptor activity |
GO:0019767 |
685 |
| IgG receptor activity |
GO:0019770 |
4 |
| Atg8 ligase activity |
GO:0019776 |
2 |
| Atg12 ligase activity |
GO:0019777 |
717 |
| APG12 activating enzyme activity |
GO:0019778 |
4 |
| APG8 activating enzyme activity |
GO:0019779 |
4 |
| NEDD8-specific protease activity |
GO:0019784 |
14 |
| ISG15-specific protease activity |
GO:0019785 |
2 |
| Small conjugating protein ligase activity |
GO:0019787 |
2406 |
| NEDD8 ligase activity |
GO:0019788 |
769 |
| SUMO ligase activity |
GO:0019789 |
14 |
| Procollagen-proline 3-dioxygenase activity |
GO:0019797 |
58 |
| Aspartoacylase activity |
GO:0019807 |
1 |
| Polyamine binding |
GO:0019808 |
3 |
| Spermidine binding |
GO:0019809 |
1 |
| Cocaine binding |
GO:0019811 |
1036 |
| Oxygen binding |
GO:0019825 |
2017 |
| Oxygen sensor activity |
GO:0019826 |
350 |
| Aspartic-type endopeptidase inhibitor activity |
GO:0019828 |
14 |
| Cation-transporting ATPase activity |
GO:0019829 |
1702 |
| Phospholipase A2 inhibitor activity |
GO:0019834 |
8 |
| Growth factor binding |
GO:0019838 |
2786 |
| Isoprenoid binding |
GO:0019840 |
2 |
| Retinol binding |
GO:0019841 |
556 |
| Vitamin binding |
GO:0019842 |
2 |
| RRNA binding |
GO:0019843 |
1829 |
| Calcium channel inhibitor activity |
GO:0019855 |
33 |
| IgA binding |
GO:0019862 |
1302 |
| IgE binding |
GO:0019863 |
685 |
| IgG binding |
GO:0019864 |
471 |
| Immunoglobulin binding |
GO:0019865 |
10 |
| Chloride channel inhibitor activity |
GO:0019869 |
633 |
| Potassium channel inhibitor activity |
GO:0019870 |
523 |
| Sodium channel inhibitor activity |
GO:0019871 |
513 |
| Protein kinase regulator activity |
GO:0019887 |
23 |
| Protein phosphatase regulator activity |
GO:0019888 |
10 |
| Kinesin binding |
GO:0019894 |
3381 |
| Enzyme binding |
GO:0019899 |
6311 |
| Kinase binding |
GO:0019900 |
3845 |
| Protein kinase binding |
GO:0019901 |
6010 |
| Phosphatase binding |
GO:0019902 |
2531 |
| Protein phosphatase binding |
GO:0019903 |
3099 |
| Protein domain specific binding |
GO:0019904 |
5613 |
| Syntaxin binding |
GO:0019905 |
3417 |
| Structural constituent of myelin sheath |
GO:0019911 |
1191 |
| Cyclin-dependent protein kinase activating kinase activity |
GO:0019912 |
5 |
| SUMO activating enzyme activity |
GO:0019948 |
11 |
| Cytokine binding |
GO:0019955 |
1517 |
| C-C chemokine binding |
GO:0019957 |
889 |
| Interleukin-8 binding |
GO:0019959 |
287 |
| Type I interferon binding |
GO:0019962 |
604 |
| Interferon-gamma binding |
GO:0019964 |
5 |
| Interleukin-1 binding |
GO:0019966 |
744 |
| Interleukin-11 binding |
GO:0019970 |
6 |
| Interleukin-2 binding |
GO:0019976 |
237 |
| Interleukin-6 binding |
GO:0019981 |
1362 |
| Diacylglycerol binding |
GO:0019992 |
1313 |
| Heme binding |
GO:0020037 |
4821 |
| Transmitter-gated ion channel activity |
GO:0022824 |
20 |
| Wide pore channel activity |
GO:0022829 |
6 |
| Leak channel activity |
GO:0022840 |
2 |
| Potassium ion leak channel activity |
GO:0022841 |
159 |
| Voltage-gated cation channel activity |
GO:0022843 |
214 |
| Acetylcholine-gated cation channel activity |
GO:0022848 |
520 |
| GABA-gated chloride ion channel activity |
GO:0022851 |
5 |
| Transmembrane transporter activity |
GO:0022857 |
2679 |
| Transmembrane electron transfer carrier |
GO:0022865 |
428 |
| Inorganic cation transmembrane transporter activity |
GO:0022890 |
652 |
| Substrate-specific transmembrane transporter activity |
GO:0022891 |
387 |
| Intermediate conductance calcium-activated potassium channel activity |
GO:0022894 |
5 |
| MHC class II protein complex binding |
GO:0023026 |
987 |
| MHC class Ib protein binding |
GO:0023029 |
29 |
| Extracellular matrix structural constituent conferring tensile strength |
GO:0030020 |
34 |
| Extracellular matrix constituent conferring elasticity |
GO:0030023 |
14 |
| L-malate dehydrogenase activity |
GO:0030060 |
2 |
| HLA-A specific inhibitory MHC class I receptor activity |
GO:0030107 |
567 |
| HLA-A specific activating MHC class I receptor activity |
GO:0030108 |
2 |
| HLA-B specific inhibitory MHC class I receptor activity |
GO:0030109 |
568 |
| Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity |
GO:0030144 |
2 |
| Manganese ion binding |
GO:0030145 |
4095 |
| Molybdenum ion binding |
GO:0030151 |
23 |
| Benzodiazepine receptor binding |
GO:0030156 |
19 |
| Protein xylosyltransferase activity |
GO:0030158 |
22 |
| Receptor signaling complex scaffold activity |
GO:0030159 |
2114 |
| GKAP/Homer scaffold activity |
GO:0030160 |
24 |
| PDZ domain binding |
GO:0030165 |
4629 |
| Low-density lipoprotein particle binding |
GO:0030169 |
1302 |
| Pyridoxal phosphate binding |
GO:0030170 |
3486 |
| Voltage-gated proton channel activity |
GO:0030171 |
1 |
| Troponin C binding |
GO:0030172 |
3 |
| Nitric oxide transmembrane transporter activity |
GO:0030184 |
11 |
| Extracellular matrix constituent, lubricant activity |
GO:0030197 |
14 |
| Semaphorin receptor binding |
GO:0030215 |
1053 |
| Very-low-density lipoprotein particle receptor activity |
GO:0030229 |
1051 |
| Deoxynucleotide transmembrane transporter activity |
GO:0030233 |
1 |
| Enzyme regulator activity |
GO:0030234 |
1566 |
| Nitric-oxide synthase regulator activity |
GO:0030235 |
28 |
| Carbohydrate binding |
GO:0030246 |
4767 |
| Polysaccharide binding |
GO:0030247 |
1330 |
| Guanylate cyclase activator activity |
GO:0030250 |
3 |
| Guanylate cyclase inhibitor activity |
GO:0030251 |
4 |
| Melanin-concentrating hormone receptor activity |
GO:0030273 |
3 |
| LIM domain binding |
GO:0030274 |
433 |
| LRR domain binding |
GO:0030275 |
472 |
| Clathrin binding |
GO:0030276 |
1140 |
| Structural constituent of epidermis |
GO:0030280 |
22 |
| Estrogen receptor activity |
GO:0030284 |
496 |
| Protein serine/threonine kinase inhibitor activity |
GO:0030291 |
974 |
| Protein tyrosine kinase inhibitor activity |
GO:0030292 |
707 |
| Protein kinase activator activity |
GO:0030295 |
1478 |
| Protein tyrosine kinase activator activity |
GO:0030296 |
1539 |
| Transmembrane receptor protein tyrosine kinase activator activity |
GO:0030297 |
349 |
| Receptor signaling protein tyrosine kinase activator activity |
GO:0030298 |
1121 |
| Heparanase activity |
GO:0030305 |
1116 |
| ADP-ribosylation factor binding |
GO:0030306 |
1530 |
| Estrogen receptor binding |
GO:0030331 |
948 |
| Cyclin binding |
GO:0030332 |
1606 |
| DNA polymerase processivity factor activity |
GO:0030337 |
1 |
| 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity |
GO:0030342 |
8 |
| Vitamin D3 25-hydroxylase activity |
GO:0030343 |
375 |
| Structural constituent of tooth enamel |
GO:0030345 |
654 |
| Protein phosphatase 2B binding |
GO:0030346 |
58 |
| Syntaxin-3 binding |
GO:0030348 |
3 |
| Iron-responsive element binding |
GO:0030350 |
1061 |
| Protein phosphatase type 4 regulator activity |
GO:0030362 |
5 |
| Interleukin-17 receptor activity |
GO:0030368 |
2098 |
| ICAM-3 receptor activity |
GO:0030369 |
507 |
| Translation repressor activity |
GO:0030371 |
15 |
| High molecular weight B cell growth factor receptor binding |
GO:0030372 |
12 |
| Ligand-dependent nuclear receptor transcription coactivator activity |
GO:0030374 |
3132 |
| Thyroid hormone receptor coactivator activity |
GO:0030375 |
17 |
| U-plasminogen activator receptor activity |
GO:0030377 |
135 |
| Serine racemase activity |
GO:0030378 |
1 |
| Neurotensin receptor activity, non-G-protein coupled |
GO:0030379 |
5 |
| Interleukin-17E receptor binding |
GO:0030380 |
2 |
| Lactose binding |
GO:0030395 |
36 |
| Glutamate formimidoyltransferase activity |
GO:0030409 |
4 |
| Formimidoyltetrahydrofolate cyclodeaminase activity |
GO:0030412 |
4 |
| Peptidase inhibitor activity |
GO:0030414 |
563 |
| Hemoglobin binding |
GO:0030492 |
1 |
| Ankyrin binding |
GO:0030506 |
1959 |
| Spectrin binding |
GO:0030507 |
2802 |
| SnoRNA binding |
GO:0030515 |
687 |
| SnoRNP binding |
GO:0030519 |
1 |
| Hsp70 protein binding |
GO:0030544 |
2707 |
| Receptor activator activity |
GO:0030546 |
37 |
| Acetylcholine receptor regulator activity |
GO:0030548 |
6 |
| Acetylcholine receptor activator activity |
GO:0030549 |
1 |
| Cyclic nucleotide binding |
GO:0030551 |
161 |
| CAMP binding |
GO:0030552 |
1929 |
| CGMP binding |
GO:0030553 |
1830 |
| Adenyl nucleotide binding |
GO:0030554 |
1866 |
| Transforming growth factor beta receptor, common-partner cytoplasmic mediator activity |
GO:0030616 |
562 |
| Transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity |
GO:0030617 |
8 |
| Transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity |
GO:0030618 |
1807 |
| U1 snRNA binding |
GO:0030619 |
5 |
| U2 snRNA binding |
GO:0030620 |
7 |
| U4 snRNA binding |
GO:0030621 |
308 |
| U6atac snRNA binding |
GO:0030624 |
3 |
| Pre-mRNA 3'-splice site binding |
GO:0030628 |
735 |
| Protein binding, bridging |
GO:0030674 |
3075 |
| Rac GTPase activator activity |
GO:0030675 |
70 |
| Rac guanyl-nucleotide exchange factor activity |
GO:0030676 |
805 |
| GTPase regulator activity |
GO:0030695 |
749 |
| Guanidinoacetate N-methyltransferase activity |
GO:0030731 |
526 |
| GTP-dependent protein binding |
GO:0030742 |
2146 |
| Amine N-methyltransferase activity |
GO:0030748 |
1026 |
| Arsenite methyltransferase activity |
GO:0030791 |
1323 |
| Methylarsonite methyltransferase activity |
GO:0030792 |
1323 |
| Beta-2-microglobulin binding |
GO:0030881 |
1076 |
| Lipid antigen binding |
GO:0030882 |
116 |
| Endogenous lipid antigen binding |
GO:0030883 |
118 |
| Exogenous lipid antigen binding |
GO:0030884 |
118 |
| Actin-dependent ATPase activity |
GO:0030898 |
1364 |
| Calcium-dependent ATPase activity |
GO:0030899 |
13 |
| TPR domain binding |
GO:0030911 |
9 |
| Endoplasmic reticulum signal peptide binding |
GO:0030942 |
7 |
| Potassium ion binding |
GO:0030955 |
1160 |
| Tat protein binding |
GO:0030957 |
590 |
| Receptor tyrosine kinase binding |
GO:0030971 |
2201 |
| Thiamine binding |
GO:0030975 |
1 |
| Thiamine pyrophosphate binding |
GO:0030976 |
1302 |
| Taurine binding |
GO:0030977 |
21 |
| Mismatched DNA binding |
GO:0030983 |
878 |
| Kininogen binding |
GO:0030984 |
456 |
| Filamin binding |
GO:0031005 |
3223 |
| Troponin I binding |
GO:0031013 |
5 |
| Troponin T binding |
GO:0031014 |
4 |
| Cysteine desulfurase activity |
GO:0031071 |
2 |
| Heat shock protein binding |
GO:0031072 |
3374 |
| Cholesterol 26-hydroxylase activity |
GO:0031073 |
1 |
| POZ domain binding |
GO:0031208 |
10 |
| Phosphatidylcholine binding |
GO:0031210 |
1132 |
| Small GTPase binding |
GO:0031267 |
1010 |
| Translation initiation factor binding |
GO:0031369 |
923 |
| Eukaryotic initiation factor 4G binding |
GO:0031370 |
302 |
| Protein tag |
GO:0031386 |
1131 |
| Sodium ion binding |
GO:0031402 |
886 |
| Lithium ion binding |
GO:0031403 |
907 |
| Chloride ion binding |
GO:0031404 |
66 |
| Carboxylic acid binding |
GO:0031406 |
35 |
| L-ascorbic acid binding |
GO:0031418 |
1649 |
| Cobalamin binding |
GO:0031419 |
1672 |
| Titin binding |
GO:0031432 |
52 |
| Telethonin binding |
GO:0031433 |
148 |
| Mitogen-activated protein kinase kinase binding |
GO:0031434 |
250 |
| Mitogen-activated protein kinase kinase kinase binding |
GO:0031435 |
2996 |
| Myosin V binding |
GO:0031489 |
2972 |
| Chromatin DNA binding |
GO:0031490 |
1607 |
| Nucleosome binding |
GO:0031491 |
1358 |
| Nucleosomal DNA binding |
GO:0031492 |
2548 |
| Nucleosomal histone binding |
GO:0031493 |
762 |
| Thyrotropin-releasing hormone receptor binding |
GO:0031531 |
3 |
| Peptidyl-proline dioxygenase activity |
GO:0031543 |
270 |
| Peptidyl-proline 4-dioxygenase activity |
GO:0031545 |
272 |
| Polyubiquitin binding |
GO:0031593 |
1208 |
| Ubiquitin conjugating enzyme binding |
GO:0031624 |
2260 |
| Ubiquitin protein ligase binding |
GO:0031625 |
5419 |
| Beta-endorphin binding |
GO:0031626 |
6 |
| Opioid receptor binding |
GO:0031628 |
575 |
| G-protein beta-subunit binding |
GO:0031681 |
2343 |
| G-protein beta/gamma-subunit complex binding |
GO:0031683 |
2146 |
| Adenosine receptor binding |
GO:0031685 |
1293 |
| A1 adenosine receptor binding |
GO:0031686 |
2 |
| A2A adenosine receptor binding |
GO:0031687 |
8 |
| Alpha-1A adrenergic receptor binding |
GO:0031691 |
2 |
| Alpha-1B adrenergic receptor binding |
GO:0031692 |
8 |
| Alpha-2A adrenergic receptor binding |
GO:0031694 |
11 |
| Alpha-2B adrenergic receptor binding |
GO:0031695 |
2 |
| Alpha-2C adrenergic receptor binding |
GO:0031696 |
8 |
| Beta-1 adrenergic receptor binding |
GO:0031697 |
18 |
| Beta-2 adrenergic receptor binding |
GO:0031698 |
24 |
| Beta-3 adrenergic receptor binding |
GO:0031699 |
16 |
| Angiotensin receptor binding |
GO:0031701 |
14 |
| Type 1 angiotensin receptor binding |
GO:0031702 |
51 |
| Type 2 angiotensin receptor binding |
GO:0031703 |
6 |
| Apelin receptor binding |
GO:0031704 |
6 |
| Endothelin A receptor binding |
GO:0031707 |
7 |
| Endothelin B receptor binding |
GO:0031708 |
7 |
| Bradykinin receptor binding |
GO:0031711 |
6 |
| C5a anaphylatoxin chemotactic receptor binding |
GO:0031714 |
4 |
| C5L2 anaphylatoxin chemotactic receptor binding |
GO:0031715 |
5 |
| Haptoglobin binding |
GO:0031720 |
1 |
| Hemoglobin alpha binding |
GO:0031721 |
3 |
| CXCR5 chemokine receptor binding |
GO:0031724 |
2 |
| CCR1 chemokine receptor binding |
GO:0031726 |
1124 |
| CCR2 chemokine receptor binding |
GO:0031727 |
8 |
| CCR4 chemokine receptor binding |
GO:0031729 |
1121 |
| CCR5 chemokine receptor binding |
GO:0031730 |
1134 |
| CCR7 chemokine receptor binding |
GO:0031732 |
1 |
| CCR10 chemokine receptor binding |
GO:0031735 |
5 |
| Type B gastrin/cholecystokinin receptor binding |
GO:0031741 |
2 |
| D1 dopamine receptor binding |
GO:0031748 |
32 |
| D2 dopamine receptor binding |
GO:0031749 |
12 |
| D3 dopamine receptor binding |
GO:0031750 |
13 |
| D4 dopamine receptor binding |
GO:0031751 |
12 |
| D5 dopamine receptor binding |
GO:0031752 |
13 |
| Edg-2 lysophosphatidic acid receptor binding |
GO:0031755 |
3 |
| Follicle-stimulating hormone receptor binding |
GO:0031762 |
2 |
| Ghrelin receptor binding |
GO:0031768 |
1 |
| Growth hormone-releasing hormone receptor binding |
GO:0031770 |
1 |
| Type 1 hypocretin receptor binding |
GO:0031771 |
1 |
| Type 2 hypocretin receptor binding |
GO:0031772 |
1 |
| Corticotropin hormone receptor binding |
GO:0031780 |
5 |
| Type 3 melanocortin receptor binding |
GO:0031781 |
5 |
| Type 4 melanocortin receptor binding |
GO:0031782 |
5 |
| Type 5 melanocortin receptor binding |
GO:0031783 |
5 |
| Type 3 metabotropic glutamate receptor binding |
GO:0031800 |
2 |
| Type 5 metabotropic glutamate receptor binding |
GO:0031802 |
4 |
| P2Y1 nucleotide receptor binding |
GO:0031812 |
7 |
| G-protein coupled serotonin receptor binding |
GO:0031821 |
7 |
| Type 2A serotonin receptor binding |
GO:0031826 |
11 |
| Olfactory receptor binding |
GO:0031849 |
11 |
| Mu-type opioid receptor binding |
GO:0031852 |
14 |
| Pituitary adenylate cyclase-activating polypeptide receptor binding |
GO:0031858 |
4 |
| Prolactin-releasing peptide receptor binding |
GO:0031861 |
1 |
| EP4 subtype prostaglandin E2 receptor binding |
GO:0031867 |
3 |
| Thromboxane A2 receptor binding |
GO:0031870 |
207 |
| Proteinase activated receptor binding |
GO:0031871 |
6 |
| Somatostatin receptor binding |
GO:0031877 |
9 |
| Taste receptor binding |
GO:0031883 |
3 |
| V1A vasopressin receptor binding |
GO:0031894 |
678 |
| V1B vasopressin receptor binding |
GO:0031895 |
1 |
| Very long-chain fatty acid-CoA ligase activity |
GO:0031957 |
4 |
| Insulin-like growth factor I binding |
GO:0031994 |
59 |
| Insulin-like growth factor II binding |
GO:0031995 |
51 |
| Thioesterase binding |
GO:0031996 |
731 |
| Myosin light chain binding |
GO:0032027 |
10 |
| Myosin head/neck binding |
GO:0032028 |
3 |
| Myosin tail binding |
GO:0032029 |
18 |
| Myosin heavy chain binding |
GO:0032036 |
265 |
| Myosin II heavy chain binding |
GO:0032038 |
3 |
| NAD-dependent histone deacetylase activity (H3-K14 specific) |
GO:0032041 |
1210 |
| Clathrin heavy chain binding |
GO:0032050 |
952 |
| Clathrin light chain binding |
GO:0032051 |
406 |
| Bile acid binding |
GO:0032052 |
133 |
| NACHT domain binding |
GO:0032089 |
1422 |
| Pyrin domain binding |
GO:0032090 |
5 |
| Guanine/thymine mispair binding |
GO:0032137 |
861 |
| Single base insertion or deletion binding |
GO:0032138 |
2 |
| Dinucleotide insertion or deletion binding |
GO:0032139 |
860 |
| Single guanine insertion binding |
GO:0032142 |
861 |
| Single thymine insertion binding |
GO:0032143 |
3 |
| Succinate-semialdehyde dehydrogenase binding |
GO:0032145 |
7 |
| Dinucleotide repeat insertion binding |
GO:0032181 |
859 |
| SUMO binding |
GO:0032183 |
23 |
| SUMO polymer binding |
GO:0032184 |
268 |
| Acrosin binding |
GO:0032190 |
7 |
| Phosphatidylinositol-3-phosphate binding |
GO:0032266 |
3197 |
| Oxidized purine DNA binding |
GO:0032357 |
861 |
| MHC class I receptor activity |
GO:0032393 |
1388 |
| MHC class II receptor activity |
GO:0032395 |
797 |
| Inhibitory MHC class I receptor activity |
GO:0032396 |
22 |
| Protein complex binding |
GO:0032403 |
5517 |
| MutLalpha complex binding |
GO:0032405 |
15 |
| MutLbeta complex binding |
GO:0032406 |
6 |
| MutSalpha complex binding |
GO:0032407 |
13 |
| MutSbeta complex binding |
GO:0032408 |
6 |
| Purine-rich negative regulatory element binding |
GO:0032422 |
4 |
| GBD domain binding |
GO:0032427 |
6 |
| Beta-N-acetylgalactosaminidase activity |
GO:0032428 |
754 |
| DNA hairpin binding |
GO:0032448 |
15 |
| Maltose alpha-glucosidase activity |
GO:0032450 |
6 |
| Demethylase activity |
GO:0032451 |
1812 |
| Histone demethylase activity |
GO:0032452 |
33 |
| Histone demethylase activity (H3-K9 specific) |
GO:0032454 |
20 |
| Muramyl dipeptide binding |
GO:0032500 |
6 |
| Sulfiredoxin activity |
GO:0032542 |
7 |
| Ribonucleoside binding |
GO:0032549 |
425 |
| Pyrimidine ribonucleotide binding |
GO:0032557 |
2 |
| DATP binding |
GO:0032564 |
2 |
| Copper-dependent protein binding |
GO:0032767 |
455 |
| Lead ion binding |
GO:0032791 |
2 |
| GTPase activating protein binding |
GO:0032794 |
956 |
| Heterotrimeric G-protein binding |
GO:0032795 |
9 |
| Sterol response element binding |
GO:0032810 |
7 |
| Tumor necrosis factor receptor superfamily binding |
GO:0032813 |
136 |
| Calcitonin binding |
GO:0032841 |
6 |
| Protein complex scaffold |
GO:0032947 |
2243 |
| Bitter taste receptor activity |
GO:0033038 |
28 |
| Sour taste receptor activity |
GO:0033040 |
9 |
| Sweet taste receptor activity |
GO:0033041 |
7 |
| Acetylcholine receptor binding |
GO:0033130 |
39 |
| Progesterone receptor binding |
GO:0033142 |
16 |
| FFAT motif binding |
GO:0033149 |
415 |
| Glycolipid 6-alpha-mannosyltransferase activity |
GO:0033164 |
3 |
| Sphingomyelin synthase activity |
GO:0033188 |
9 |
| Calmodulin-dependent protein phosphatase activity |
GO:0033192 |
57 |
| Ribonuclease P RNA binding |
GO:0033204 |
3 |
| Choline binding |
GO:0033265 |
289 |
| Dehydroascorbic acid transporter activity |
GO:0033300 |
14 |
| MAP kinase phosphatase activity |
GO:0033549 |
8 |
| Protein deacetylase activity |
GO:0033558 |
1159 |
| Activating transcription factor binding |
GO:0033613 |
1822 |
| DNA/RNA helicase activity |
GO:0033677 |
4 |
| ATP-dependent 5'-3' DNA/RNA helicase activity |
GO:0033682 |
2 |
| Sialic acid binding |
GO:0033691 |
1586 |
| 1-pyrroline dehydrogenase activity |
GO:0033737 |
2 |
| Peptide-methionine (R)-S-oxide reductase activity |
GO:0033743 |
943 |
| Histone demethylase activity (H3-R2 specific) |
GO:0033746 |
748 |
| Histone demethylase activity (H4-R3 specific) |
GO:0033749 |
748 |
| 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity |
GO:0033778 |
675 |
| Taurochenodeoxycholate 6alpha-hydroxylase activity |
GO:0033780 |
374 |
| Thyroxine 5-deiodinase activity |
GO:0033798 |
2 |
| Propanoyl-CoA C-acyltransferase activity |
GO:0033814 |
8 |
| Procollagen glucosyltransferase activity |
GO:0033823 |
5 |
| O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity |
GO:0033829 |
11 |
| N-acetylgalactosamine kinase activity |
GO:0033858 |
215 |
| [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity |
GO:0033871 |
1 |
| [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity |
GO:0033872 |
4 |
| Hormone-sensitive lipase activity |
GO:0033878 |
4 |
| Pyridoxal phosphatase activity |
GO:0033883 |
2 |
| Ribonuclease T2 activity |
GO:0033897 |
4 |
| Hyaluronoglucuronidase activity |
GO:0033906 |
2 |
| Cis-stilbene-oxide hydrolase activity |
GO:0033961 |
1 |
| Deoxyhypusine synthase activity |
GO:0034038 |
96 |
| 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity |
GO:0034039 |
5 |
| Lipid-transporting ATPase activity |
GO:0034040 |
10 |
| Poly(G) RNA binding |
GO:0034046 |
16 |
| Estrogen response element binding |
GO:0034056 |
501 |
| DNA polymerase activity |
GO:0034061 |
3 |
| Apolipoprotein binding |
GO:0034185 |
63 |
| Apolipoprotein A-I receptor activity |
GO:0034188 |
11 |
| Very-low-density lipoprotein particle binding |
GO:0034189 |
7 |
| Apolipoprotein receptor binding |
GO:0034190 |
6 |
| Apolipoprotein A-I receptor binding |
GO:0034191 |
288 |
| GTP-dependent protein kinase activity |
GO:0034211 |
11 |
| GPI anchor binding |
GO:0034235 |
1386 |
| Protein kinase A catalytic subunit binding |
GO:0034236 |
54 |
| Protein kinase A regulatory subunit binding |
GO:0034237 |
48 |
| Bisphosphoglycerate 3-phosphatase activity |
GO:0034417 |
4 |
| Glycoprotein transporter activity |
GO:0034437 |
3 |
| Ubiquitin-ubiquitin ligase activity |
GO:0034450 |
68 |
| Dynactin binding |
GO:0034452 |
48 |
| 3'-5' RNA helicase activity |
GO:0034458 |
2 |
| U3 snoRNA binding |
GO:0034511 |
2 |
| Fumarylpyruvate hydrolase activity |
GO:0034545 |
700 |
| PiRNA binding |
GO:0034584 |
857 |
| L-hydroxyproline transmembrane transporter activity |
GO:0034590 |
12 |
| Phosphatidylinositol bisphosphate phosphatase activity |
GO:0034593 |
8 |
| Phosphatidylinositol trisphosphate phosphatase activity |
GO:0034594 |
9 |
| Phosphatidylinositol phosphate 5-phosphatase activity |
GO:0034595 |
15 |
| Phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity |
GO:0034597 |
9 |
| Oxoglutarate dehydrogenase (NAD+) activity |
GO:0034602 |
708 |
| Tetrahydrobiopterin binding |
GO:0034617 |
1489 |
| Arginine binding |
GO:0034618 |
1487 |
| Retinol transporter activity |
GO:0034632 |
1 |
| Tripeptidase activity |
GO:0034701 |
240 |
| Inhibin binding |
GO:0034711 |
30 |
| Type I transforming growth factor beta receptor binding |
GO:0034713 |
738 |
| Type III transforming growth factor beta receptor binding |
GO:0034714 |
4 |
| Gamma-glutamyl-peptidase activity |
GO:0034722 |
2 |
| Cholesterol O-acyltransferase activity |
GO:0034736 |
1408 |
| Caffeine oxidase activity |
GO:0034875 |
1559 |
| Trimethylamine monooxygenase activity |
GO:0034899 |
1 |
| NAD-dependent protein deacetylase activity |
GO:0034979 |
5 |
| Iron chaperone activity |
GO:0034986 |
1923 |
| Immunoglobulin receptor binding |
GO:0034987 |
8 |
| Fc-gamma receptor I complex binding |
GO:0034988 |
6 |
| Phosphatidylinositol 3-kinase activity |
GO:0035004 |
1422 |
| 1-phosphatidylinositol-4-phosphate 3-kinase activity |
GO:0035005 |
2042 |
| Phosphatidylinositol 3-kinase regulator activity |
GO:0035014 |
493 |
| Histone deacetylase regulator activity |
GO:0035033 |
257 |
| Histone acetyltransferase regulator activity |
GO:0035034 |
2 |
| Histone acetyltransferase binding |
GO:0035035 |
1494 |
| Methylated histone residue binding |
GO:0035064 |
3342 |
| Phosphatidylinositol binding |
GO:0035091 |
3734 |
| Histone kinase activity |
GO:0035173 |
13 |
| Histone serine kinase activity |
GO:0035174 |
2018 |
| SiRNA binding |
GO:0035197 |
717 |
| MiRNA binding |
GO:0035198 |
1513 |
| Glutamate-cysteine ligase catalytic subunit binding |
GO:0035226 |
1043 |
| Dopamine binding |
GO:0035240 |
23 |
| Protein-arginine omega-N monomethyltransferase activity |
GO:0035241 |
197 |
| Protein-arginine omega-N asymmetric methyltransferase activity |
GO:0035242 |
212 |
| Protein-arginine omega-N symmetric methyltransferase activity |
GO:0035243 |
200 |
| Alpha-1,4-N-acetylgalactosaminyltransferase activity |
GO:0035248 |
4 |
| UDP-galactosyltransferase activity |
GO:0035250 |
7 |
| Glutamate receptor binding |
GO:0035254 |
17 |
| Ionotropic glutamate receptor binding |
GO:0035255 |
160 |
| G-protein coupled glutamate receptor binding |
GO:0035256 |
6 |
| Nuclear hormone receptor binding |
GO:0035257 |
2516 |
| Steroid hormone receptor binding |
GO:0035258 |
15 |
| Glucocorticoid receptor binding |
GO:0035259 |
71 |
| Ethanol binding |
GO:0035276 |
15 |
| Inositol pentakisphosphate 2-kinase activity |
GO:0035299 |
1 |
| 5'-3' exodeoxyribonuclease activity |
GO:0035312 |
3 |
| Toll-like receptor binding |
GO:0035325 |
2 |
| Enhancer binding |
GO:0035326 |
1730 |
| Selenocysteine insertion sequence binding |
GO:0035368 |
2 |
| Chondroitin sulfate proteoglycan binding |
GO:0035373 |
322 |
| Chondroitin sulfate binding |
GO:0035374 |
501 |
| Zymogen binding |
GO:0035375 |
5 |
| Carbon dioxide transmembrane transporter activity |
GO:0035379 |
11 |
| Histone kinase activity (H3-Y41 specific) |
GO:0035401 |
11 |
| Histone kinase activity (H3-T11 specific) |
GO:0035402 |
653 |
| Histone kinase activity (H3-T6 specific) |
GO:0035403 |
902 |
| Cyclic-di-GMP binding |
GO:0035438 |
2 |
| Choriogonadotropin hormone receptor activity |
GO:0035472 |
3 |
| Lipase binding |
GO:0035473 |
2779 |
| CAMP response element binding |
GO:0035497 |
752 |
| MH2 domain binding |
GO:0035500 |
738 |
| MH1 domain binding |
GO:0035501 |
738 |
| Oxidative RNA demethylase activity |
GO:0035515 |
719 |
| Oxidative DNA demethylase activity |
GO:0035516 |
718 |
| NADH pyrophosphatase activity |
GO:0035529 |
831 |
| Carbohydrate response element binding |
GO:0035538 |
12 |
| 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity |
GO:0035539 |
468 |
| Histone demethylase activity (H4-K20 specific) |
GO:0035575 |
5 |
| Signaling adaptor activity |
GO:0035591 |
309 |
| Ganglioside binding |
GO:0035594 |
4 |
| N6-threonylcarbomyladenosine methylthiotransferase activity |
GO:0035598 |
911 |
| AP-2 adaptor complex binding |
GO:0035612 |
2273 |
| RNA stem-loop binding |
GO:0035613 |
13 |
| Clathrin adaptor activity |
GO:0035615 |
23 |
| Ceramide transporter activity |
GO:0035620 |
5 |
| Histone methyltransferase activity (H3-R17 specific) |
GO:0035642 |
3 |
| AP-1 adaptor complex binding |
GO:0035650 |
1 |
| AP-3 adaptor complex binding |
GO:0035651 |
1 |
| Toll-like receptor 4 binding |
GO:0035662 |
248 |
| Toll-like receptor 2 binding |
GO:0035663 |
244 |
| Macrophage migration inhibitory factor binding |
GO:0035718 |
2 |
| Lysophosphatidic acid binding |
GO:0035727 |
3 |
| S-nitrosoglutathione binding |
GO:0035730 |
2 |
| Dinitrosyl-iron complex binding |
GO:0035731 |
2 |
| Chemokine (C-C motif) ligand 19 binding |
GO:0035757 |
4 |
| Chemokine (C-C motif) ligand 21 binding |
GO:0035758 |
4 |
| Ubiquitin-specific protease activator activity |
GO:0035800 |
4 |
| Rubidium ion transmembrane transporter activity |
GO:0035827 |
1680 |
| Krueppel-associated box domain binding |
GO:0035851 |
1015 |
| DITP diphosphatase activity |
GO:0035870 |
12 |
| Death effector domain binding |
GO:0035877 |
2677 |
| MRNA 3'-UTR AU-rich region binding |
GO:0035925 |
29 |
| Microsatellite binding |
GO:0035939 |
7 |
| Pre-mRNA binding |
GO:0036002 |
7 |
| Mediator complex binding |
GO:0036033 |
21 |
| Long-chain fatty acid binding |
GO:0036041 |
4 |
| Long-chain fatty acyl-CoA binding |
GO:0036042 |
9 |
| Protein-malonyllysine demalonylase activity |
GO:0036054 |
713 |
| Protein-succinyllysine desuccinylase activity |
GO:0036055 |
713 |
| Small molecule binding |
GO:0036094 |
11 |
| Peroxisome membrane class-1 targeting sequence binding |
GO:0036105 |
3 |
| BMP binding |
GO:0036122 |
7 |
| Peptidyl-histidine dioxygenase activity |
GO:0036139 |
20 |
| Peptidyl-asparagine 3-dioxygenase activity |
GO:0036140 |
20 |
| ITP diphosphatase activity |
GO:0036220 |
2 |
| XTP diphosphatase activity |
GO:0036222 |
2 |
| NA |
GO:0036310 |
838 |
| NA |
GO:0036312 |
6 |
| NA |
GO:0036313 |
3 |
| NA |
GO:0036326 |
629 |
| NA |
GO:0036327 |
629 |
| NA |
GO:0036332 |
629 |
| NA |
GO:0036374 |
745 |
| NA |
GO:0036393 |
2 |
| NA |
GO:0036403 |
66 |
| NA |
GO:0036459 |
3819 |
| NA |
GO:0036461 |
1 |
| NA |
GO:0036468 |
1 |
| NA |
GO:0036470 |
1 |
| NA |
GO:0036478 |
1 |
| NA |
GO:0036479 |
11 |
| NA |
GO:0036487 |
8 |
| Signaling receptor activity |
GO:0038023 |
607 |
| Cargo receptor activity |
GO:0038024 |
6 |
| Reelin receptor activity |
GO:0038025 |
16 |
| Morphine receptor activity |
GO:0038047 |
1710 |
| Dynorphin receptor activity |
GO:0038048 |
801 |
| Ligand-activated RNA polymerase II transcription factor binding transcription factor activity |
GO:0038049 |
16 |
| Glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity |
GO:0038051 |
9 |
| Estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
GO:0038052 |
8 |
| Protein tyrosine kinase collagen receptor activity |
GO:0038062 |
10 |
| Collagen receptor activity |
GO:0038064 |
737 |
| Vascular endothelial growth factor binding |
GO:0038085 |
199 |
| Nodal binding |
GO:0038100 |
13 |
| Choriogonadotropin hormone binding |
GO:0038106 |
3 |
| C-C motif chemokine 19 receptor activity |
GO:0038117 |
4 |
| C-C motif chemokine 21 receptor activity |
GO:0038121 |
4 |
| NA |
GO:0038181 |
126 |
| NA |
GO:0038186 |
415 |
| NA |
GO:0038191 |
6 |
| Interleukin-18 binding |
GO:0042007 |
3 |
| Interleukin-18 receptor activity |
GO:0042008 |
2 |
| Interleukin-20 binding |
GO:0042015 |
5 |
| Interleukin-22 binding |
GO:0042017 |
6 |
| Interleukin-22 receptor activity |
GO:0042018 |
6 |
| Interleukin-23 binding |
GO:0042019 |
937 |
| Interleukin-23 receptor activity |
GO:0042020 |
937 |
| ATPase inhibitor activity |
GO:0042030 |
8 |
| Neurexin family protein binding |
GO:0042043 |
546 |
| Histone methyltransferase activity |
GO:0042054 |
30 |
| Chemoattractant activity |
GO:0042056 |
1520 |
| Thiamine phosphate phosphatase activity |
GO:0042131 |
283 |
| Fructose 1,6-bisphosphate 1-phosphatase activity |
GO:0042132 |
2 |
| RRNA primary transcript binding |
GO:0042134 |
432 |
| Telomeric DNA binding |
GO:0042162 |
1299 |
| Interleukin-12 beta subunit binding |
GO:0042163 |
2 |
| Interleukin-12 alpha subunit binding |
GO:0042164 |
134 |
| Neurotransmitter binding |
GO:0042165 |
8 |
| Acetylcholine binding |
GO:0042166 |
1311 |
| SH2 domain binding |
GO:0042169 |
2343 |
| Lysophosphatidic acid acyltransferase activity |
GO:0042171 |
104 |
| Peptide binding |
GO:0042277 |
2897 |
| Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity |
GO:0042281 |
69 |
| Hydroxymethylglutaryl-CoA reductase activity |
GO:0042282 |
4 |
| Xylosyltransferase activity |
GO:0042285 |
3 |
| MHC protein binding |
GO:0042287 |
853 |
| MHC class I protein binding |
GO:0042288 |
2508 |
| MHC class II protein binding |
GO:0042289 |
9 |
| ISG15 ligase activity |
GO:0042296 |
5 |
| Phosphate ion binding |
GO:0042301 |
1153 |
| Heparan sulfate N-acetylglucosaminyltransferase activity |
GO:0042328 |
3 |
| Chemokine receptor binding |
GO:0042379 |
1131 |
| Sphingosine-1-phosphate phosphatase activity |
GO:0042392 |
3 |
| Histone binding |
GO:0042393 |
4835 |
| Diacyl lipopeptide binding |
GO:0042498 |
652 |
| Aspartic endopeptidase activity, intramembrane cleaving |
GO:0042500 |
9 |
| Hormone binding |
GO:0042562 |
31 |
| Phosphoric ester hydrolase activity |
GO:0042578 |
148 |
| Riboflavin reductase (NADPH) activity |
GO:0042602 |
1 |
| Peptide antigen binding |
GO:0042605 |
3427 |
| T cell receptor binding |
GO:0042608 |
627 |
| CD4 receptor binding |
GO:0042609 |
15 |
| CD8 receptor binding |
GO:0042610 |
8 |
| ATPase activity, coupled |
GO:0042623 |
27 |
| ATPase activity, uncoupled |
GO:0042624 |
1 |
| ATPase activity, coupled to transmembrane movement of ions |
GO:0042625 |
2 |
| ATPase activity, coupled to transmembrane movement of substances |
GO:0042626 |
1714 |
| MHC class II protein binding, via antigen binding groove |
GO:0042658 |
2 |
| PH domain binding |
GO:0042731 |
13 |
| Histone methyltransferase activity (H4-K20 specific) |
GO:0042799 |
15 |
| Histone methyltransferase activity (H3-K4 specific) |
GO:0042800 |
57 |
| Polo kinase kinase activity |
GO:0042801 |
546 |
| Identical protein binding |
GO:0042802 |
6993 |
| Protein homodimerization activity |
GO:0042803 |
7150 |
| Actinin binding |
GO:0042805 |
1772 |
| Fucose binding |
GO:0042806 |
243 |
| Vitamin D receptor binding |
GO:0042809 |
448 |
| Wnt-activated receptor activity |
GO:0042813 |
2061 |
| Histone deacetylase binding |
GO:0042826 |
3712 |
| Peptidoglycan binding |
GO:0042834 |
360 |
| Antibiotic transporter activity |
GO:0042895 |
788 |
| Tubulin deacetylase activity |
GO:0042903 |
3 |
| Xenobiotic transporter activity |
GO:0042910 |
2 |
| Neuropeptide binding |
GO:0042923 |
2550 |
| Dipeptide transporter activity |
GO:0042936 |
787 |
| Lipoprotein transporter activity |
GO:0042954 |
11 |
| Retinoic acid receptor binding |
GO:0042974 |
194 |
| Peroxisome proliferator activated receptor binding |
GO:0042975 |
2081 |
| Ornithine decarboxylase activator activity |
GO:0042978 |
121 |
| X11-like protein binding |
GO:0042988 |
2 |
| ATP-dependent protein binding |
GO:0043008 |
27 |
| Alpha-tubulin binding |
GO:0043014 |
1114 |
| Gamma-tubulin binding |
GO:0043015 |
1611 |
| Ribonucleoprotein complex binding |
GO:0043021 |
923 |
| Ribosome binding |
GO:0043022 |
2577 |
| Ribosomal large subunit binding |
GO:0043023 |
356 |
| Ribosomal small subunit binding |
GO:0043024 |
892 |
| Cysteine-type endopeptidase inhibitor activity involved in apoptotic process |
GO:0043027 |
2893 |
| Cysteine-type endopeptidase regulator activity involved in apoptotic process |
GO:0043028 |
1 |
| Chromatin insulator sequence binding |
GO:0043035 |
3 |
| Single-stranded telomeric DNA binding |
GO:0043047 |
17 |
| Tumor necrosis factor binding |
GO:0043120 |
6 |
| Neurotrophin binding |
GO:0043121 |
29 |
| ErbB-3 class receptor binding |
GO:0043125 |
34 |
| Ubiquitin binding |
GO:0043130 |
2874 |
| 3'-5' DNA helicase activity |
GO:0043138 |
6 |
| 5'-3' DNA helicase activity |
GO:0043139 |
8 |
| ATP-dependent 3'-5' DNA helicase activity |
GO:0043140 |
212 |
| ATP-dependent 5'-3' DNA helicase activity |
GO:0043141 |
7 |
| Single-stranded DNA-dependent ATPase activity |
GO:0043142 |
596 |
| Ion binding |
GO:0043167 |
53 |
| Cation binding |
GO:0043169 |
209 |
| Amine binding |
GO:0043176 |
2 |
| Organic acid binding |
GO:0043177 |
6 |
| Alcohol binding |
GO:0043178 |
4 |
| Vascular endothelial growth factor receptor 1 binding |
GO:0043183 |
8 |
| Vascular endothelial growth factor receptor 2 binding |
GO:0043184 |
24 |
| Vascular endothelial growth factor receptor 3 binding |
GO:0043185 |
3 |
| Sulfate binding |
GO:0043199 |
5 |
| Glycosphingolipid binding |
GO:0043208 |
24 |
| Laminin binding |
GO:0043236 |
2625 |
| Laminin-1 binding |
GO:0043237 |
456 |
| Adenosine-diphosphatase activity |
GO:0043262 |
18 |
| Phospholipase binding |
GO:0043274 |
87 |
| Glutathione binding |
GO:0043295 |
1572 |
| Phosphatidylinositol-3,4-bisphosphate binding |
GO:0043325 |
1260 |
| Proteoglycan binding |
GO:0043394 |
2595 |
| Heparan sulfate proteoglycan binding |
GO:0043395 |
372 |
| HLH domain binding |
GO:0043398 |
216 |
| Corticotropin-releasing hormone receptor activity |
GO:0043404 |
6 |
| Protein kinase B binding |
GO:0043422 |
895 |
| 3-phosphoinositide-dependent protein kinase binding |
GO:0043423 |
7 |
| BHLH transcription factor binding |
GO:0043425 |
347 |
| MRF binding |
GO:0043426 |
38 |
| Protein anchor |
GO:0043495 |
550 |
| Kinetochore binding |
GO:0043515 |
414 |
| Leucine zipper domain binding |
GO:0043522 |
2060 |
| ADP binding |
GO:0043531 |
2394 |
| Angiostatin binding |
GO:0043532 |
15 |
| Protein serine/threonine kinase activator activity |
GO:0043539 |
273 |
| Molybdopterin cofactor binding |
GO:0043546 |
275 |
| Phosphatidylinositol 3-kinase binding |
GO:0043548 |
90 |
| Insulin binding |
GO:0043559 |
61 |
| Insulin receptor substrate binding |
GO:0043560 |
772 |
| Sequence-specific DNA binding |
GO:0043565 |
6209 |
| Structure-specific DNA binding |
GO:0043566 |
1271 |
| Protein self-association |
GO:0043621 |
2000 |
| DNA-N1-methyladenine dioxygenase activity |
GO:0043734 |
721 |
| Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity |
GO:0043754 |
1769 |
| Phosphatidylinositol-4-phosphate phosphatase activity |
GO:0043812 |
8 |
| Phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity |
GO:0043813 |
506 |
| Ras palmitoyltransferase activity |
GO:0043849 |
12 |
| Acireductone synthase activity |
GO:0043874 |
2 |
| NADPH:sulfur oxidoreductase activity |
GO:0043914 |
9 |
| Suramin binding |
GO:0043924 |
8 |
| Histone acetyltransferase activity (H4-K5 specific) |
GO:0043995 |
587 |
| Histone acetyltransferase activity (H4-K8 specific) |
GO:0043996 |
587 |
| Histone methyltransferase activity (H4-R3 specific) |
GO:0044020 |
197 |
| Protein binding involved in protein folding |
GO:0044183 |
459 |
| Transcription regulatory region DNA binding |
GO:0044212 |
3987 |
| Retinoic acid-responsive element binding |
GO:0044323 |
14 |
| Ion channel binding |
GO:0044325 |
3572 |
| Small protein activating enzyme binding |
GO:0044388 |
1 |
| Small protein conjugating enzyme binding |
GO:0044390 |
1 |
| L-cystine L-cysteine-lyase (deaminating) |
GO:0044540 |
301 |
| S100 protein binding |
GO:0044548 |
525 |
| GTP cyclohydrolase binding |
GO:0044549 |
1 |
| FMN transmembrane transporter activity |
GO:0044610 |
2 |
| NA |
GO:0044729 |
758 |
| NA |
GO:0044822 |
7849 |
| G-protein coupled purinergic nucleotide receptor activity |
GO:0045028 |
1771 |
| UDP-activated nucleotide receptor activity |
GO:0045029 |
3 |
| ATP-activated nucleotide receptor activity |
GO:0045031 |
2 |
| ADP-activated nucleotide receptor activity |
GO:0045032 |
2 |
| Bioactive lipid receptor activity |
GO:0045125 |
1 |
| Uridine-diphosphatase activity |
GO:0045134 |
943 |
| Single-stranded DNA specific 5'-3' exodeoxyribonuclease activity |
GO:0045145 |
610 |
| Electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity |
GO:0045155 |
1949 |
| Myosin II binding |
GO:0045159 |
903 |
| Glutathione dehydrogenase (ascorbate) activity |
GO:0045174 |
1 |
| Translation regulator activity |
GO:0045182 |
182 |
| CXCR chemokine receptor binding |
GO:0045236 |
8 |
| Alpha-catenin binding |
GO:0045294 |
158 |
| Gamma-catenin binding |
GO:0045295 |
1133 |
| Cadherin binding |
GO:0045296 |
168 |
| Protein phosphorylated amino acid binding |
GO:0045309 |
755 |
| Unmethylated CpG binding |
GO:0045322 |
17 |
| Mercury ion binding |
GO:0045340 |
1 |
| Interleukin-1 Type I receptor antagonist activity |
GO:0045352 |
1 |
| Interleukin-1 Type II receptor antagonist activity |
GO:0045353 |
1 |
| Chemorepellent activity |
GO:0045499 |
37 |
| Dynein binding |
GO:0045502 |
214 |
| Dynein light chain binding |
GO:0045503 |
6 |
| Dynein heavy chain binding |
GO:0045504 |
1 |
| Dynein intermediate chain binding |
GO:0045505 |
38 |
| Interleukin-27 receptor activity |
GO:0045509 |
229 |
| Interleukin-27 binding |
GO:0045513 |
2 |
| Interleukin-20 receptor binding |
GO:0045517 |
1 |
| Interleukin-22 receptor binding |
GO:0045518 |
2 |
| Interleukin-23 receptor binding |
GO:0045519 |
134 |
| Interleukin-27 receptor binding |
GO:0045523 |
20 |
| Syndecan binding |
GO:0045545 |
1437 |
| Geranylgeranyl reductase activity |
GO:0045550 |
453 |
| TRAIL binding |
GO:0045569 |
1196 |
| SMAD binding |
GO:0046332 |
2976 |
| Polynucleotide 3'-phosphatase activity |
GO:0046403 |
2 |
| ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity |
GO:0046404 |
653 |
| S-methyl-5-thioribose-1-phosphate isomerase activity |
GO:0046523 |
1733 |
| Glucosyltransferase activity |
GO:0046527 |
4 |
| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity |
GO:0046538 |
1 |
| Histamine N-methyltransferase activity |
GO:0046539 |
150 |
| Malate dehydrogenase (NADP+) activity |
GO:0046554 |
2 |
| Long-chain-alcohol oxidase activity |
GO:0046577 |
292 |
| Rap GTPase activator activity |
GO:0046582 |
27 |
| Polyamine oxidase activity |
GO:0046592 |
1 |
| Sphingolipid transporter activity |
GO:0046624 |
7 |
| Sphingolipid binding |
GO:0046625 |
10 |
| Natural killer cell lectin-like receptor binding |
GO:0046703 |
1615 |
| Borate transmembrane transporter activity |
GO:0046715 |
3 |
| Host cell surface receptor binding |
GO:0046789 |
3 |
| Virion binding |
GO:0046790 |
985 |
| Histone deacetylase inhibitor activity |
GO:0046811 |
4 |
| Chemokine receptor antagonist activity |
GO:0046817 |
1121 |
| Hydroxyapatite binding |
GO:0046848 |
2 |
| Cadmium ion binding |
GO:0046870 |
1768 |
| Metal ion binding |
GO:0046872 |
8920 |
| Metal ion transmembrane transporter activity |
GO:0046873 |
341 |
| Ephrin receptor binding |
GO:0046875 |
1845 |
| Calcium oxalate binding |
GO:0046904 |
1 |
| Transition metal ion binding |
GO:0046914 |
5 |
| Transition metal ion transmembrane transporter activity |
GO:0046915 |
205 |
| Alpha-(1->3)-fucosyltransferase activity |
GO:0046920 |
1658 |
| Alpha-(1->6)-fucosyltransferase activity |
GO:0046921 |
28 |
| Peptide-O-fucosyltransferase activity |
GO:0046922 |
848 |
| ER retention sequence binding |
GO:0046923 |
9 |
| Hydrogen ion transporting ATP synthase activity, rotational mechanism |
GO:0046933 |
893 |
| Phosphatidylinositol-4,5-bisphosphate 3-kinase activity |
GO:0046934 |
727 |
| 1-phosphatidylinositol-3-kinase regulator activity |
GO:0046935 |
16 |
| Carboxylic acid transmembrane transporter activity |
GO:0046943 |
2 |
| Proton-transporting ATPase activity, rotational mechanism |
GO:0046961 |
1825 |
| 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity |
GO:0046964 |
4 |
| Retinoid X receptor binding |
GO:0046965 |
824 |
| Thyroid hormone receptor binding |
GO:0046966 |
1331 |
| NAD-dependent histone deacetylase activity (H3-K9 specific) |
GO:0046969 |
1068 |
| NAD-dependent histone deacetylase activity (H4-K16 specific) |
GO:0046970 |
1062 |
| Histone acetyltransferase activity (H4-K16 specific) |
GO:0046972 |
587 |
| Histone methyltransferase activity (H3-K9 specific) |
GO:0046974 |
241 |
| Histone methyltransferase activity (H3-K36 specific) |
GO:0046975 |
20 |
| Histone methyltransferase activity (H3-K27 specific) |
GO:0046976 |
22 |
| TAP binding |
GO:0046977 |
1 |
| TAP1 binding |
GO:0046978 |
1384 |
| TAP2 binding |
GO:0046979 |
1382 |
| Tapasin binding |
GO:0046980 |
2 |
| Protein heterodimerization activity |
GO:0046982 |
5758 |
| Protein dimerization activity |
GO:0046983 |
4847 |
| Sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity |
GO:0047012 |
2 |
| Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity |
GO:0047016 |
339 |
| Androsterone dehydrogenase activity |
GO:0047023 |
1 |
| Testosterone dehydrogenase (NAD+) activity |
GO:0047035 |
165 |
| Testosterone 17-beta-dehydrogenase (NADP+) activity |
GO:0047045 |
1 |
| Vitamin-K-epoxide reductase (warfarin-sensitive) activity |
GO:0047057 |
6 |
| 4-trimethylammoniobutyraldehyde dehydrogenase activity |
GO:0047105 |
2 |
| Saccharopine dehydrogenase (NADP+, L-lysine-forming) activity |
GO:0047130 |
915 |
| Saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity |
GO:0047131 |
915 |
| Protein-disulfide reductase activity |
GO:0047134 |
923 |
| Betaine-homocysteine S-methyltransferase activity |
GO:0047150 |
999 |
| Platelet-activating factor acetyltransferase activity |
GO:0047179 |
1108 |
| 1-acylglycerophosphocholine O-acyltransferase activity |
GO:0047184 |
591 |
| Cysteine-S-conjugate N-acetyltransferase activity |
GO:0047198 |
5 |
| Galactosylxylosylprotein 3-beta-galactosyltransferase activity |
GO:0047220 |
5 |
| Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity |
GO:0047223 |
708 |
| Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity |
GO:0047225 |
1 |
| Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
GO:0047238 |
392 |
| Galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity |
GO:0047273 |
190 |
| Globoside alpha-N-acetylgalactosaminyltransferase activity |
GO:0047277 |
3 |
| (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity |
GO:0047290 |
1 |
| (S)-3-amino-2-methylpropionate transaminase activity |
GO:0047298 |
7 |
| Kynurenine-glyoxylate transaminase activity |
GO:0047315 |
3 |
| [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity |
GO:0047322 |
918 |
| [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity |
GO:0047323 |
2 |
| Inositol tetrakisphosphate 1-kinase activity |
GO:0047325 |
664 |
| Fucose-1-phosphate guanylyltransferase activity |
GO:0047341 |
3 |
| Acylglycerol lipase activity |
GO:0047372 |
10 |
| Methylumbelliferyl-acetate deacetylase activity |
GO:0047374 |
4 |
| Glycerophosphocholine cholinephosphodiesterase activity |
GO:0047390 |
346 |
| Glycerophosphoinositol inositolphosphodiesterase activity |
GO:0047394 |
120 |
| Alkenylglycerophosphocholine hydrolase activity |
GO:0047408 |
1 |
| Alkenylglycerophosphoethanolamine hydrolase activity |
GO:0047409 |
1 |
| Nucleoside-triphosphate diphosphatase activity |
GO:0047429 |
826 |
| 17-alpha-hydroxyprogesterone aldolase activity |
GO:0047442 |
4 |
| Protein N-terminus binding |
GO:0047485 |
4034 |
| Ceramide cholinephosphotransferase activity |
GO:0047493 |
9 |
| Calcium-dependent phospholipase A2 activity |
GO:0047498 |
590 |
| Calcium-independent phospholipase A2 activity |
GO:0047499 |
25 |
| 2-hydroxyglutarate dehydrogenase activity |
GO:0047545 |
1217 |
| 3',5'-cyclic-GMP phosphodiesterase activity |
GO:0047555 |
2731 |
| 7-dehydrocholesterol reductase activity |
GO:0047598 |
2 |
| Acyl-CoA hydrolase activity |
GO:0047617 |
687 |
| Acylpyruvate hydrolase activity |
GO:0047621 |
700 |
| ADP-ribose diphosphatase activity |
GO:0047631 |
23 |
| Albendazole monooxygenase activity |
GO:0047638 |
374 |
| Arachidonate-CoA ligase activity |
GO:0047676 |
3 |
| ATP diphosphatase activity |
GO:0047693 |
1 |
| Beta-adrenergic receptor kinase activity |
GO:0047696 |
2 |
| Bile-salt sulfotransferase activity |
GO:0047704 |
813 |
| Biotinidase activity |
GO:0047708 |
3 |
| Bis(5'-adenosyl)-triphosphatase activity |
GO:0047710 |
5 |
| Indanol dehydrogenase activity |
GO:0047718 |
453 |
| Iron-cytochrome-c reductase activity |
GO:0047726 |
4 |
| Chlordecone reductase activity |
GO:0047743 |
1 |
| Cholate-CoA ligase activity |
GO:0047747 |
1 |
| Cholestanetriol 26-monooxygenase activity |
GO:0047749 |
1 |
| Cholestenol delta-isomerase activity |
GO:0047750 |
1 |
| Cholestenone 5-alpha-reductase activity |
GO:0047751 |
4 |
| Chondroitin 4-sulfotransferase activity |
GO:0047756 |
161 |
| Chondroitin-glucuronate 5-epimerase activity |
GO:0047757 |
2 |
| Butyrate-CoA ligase activity |
GO:0047760 |
9 |
| Corticosterone 18-monooxygenase activity |
GO:0047783 |
2 |
| Delta4-3-oxosteroid 5beta-reductase activity |
GO:0047787 |
626 |
| L-cysteine:2-oxoglutarate aminotransferase activity |
GO:0047801 |
1 |
| Cysteine-S-conjugate beta-lyase activity |
GO:0047804 |
3 |
| Deoxycytidine deaminase activity |
GO:0047844 |
702 |
| Dihydrocoumarin hydrolase activity |
GO:0047856 |
1 |
| Dolichyldiphosphatase activity |
GO:0047874 |
2 |
| Flavonol 3-sulfotransferase activity |
GO:0047894 |
236 |
| L-glucuronate reductase activity |
GO:0047939 |
60 |
| Glycine N-acyltransferase activity |
GO:0047961 |
8 |
| Glycine N-benzoyltransferase activity |
GO:0047962 |
4 |
| Glycine N-choloyltransferase activity |
GO:0047963 |
3 |
| Glyoxylate oxidase activity |
GO:0047969 |
2 |
| Hepoxilin-epoxide hydrolase activity |
GO:0047977 |
193 |
| Homocysteine desulfhydrase activity |
GO:0047982 |
301 |
| Hydroxyacid-oxoacid transhydrogenase activity |
GO:0047988 |
1 |
| Receptor agonist activity |
GO:0048018 |
38 |
| Receptor antagonist activity |
GO:0048019 |
2655 |
| CCR chemokine receptor binding |
GO:0048020 |
2 |
| MRNA 5'-UTR binding |
GO:0048027 |
46 |
| Monosaccharide binding |
GO:0048029 |
2234 |
| Cofactor binding |
GO:0048037 |
167 |
| Quinone binding |
GO:0048038 |
26 |
| Calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity |
GO:0048101 |
15 |
| Tau protein binding |
GO:0048156 |
75 |
| Activin binding |
GO:0048185 |
524 |
| Phytanoyl-CoA dioxygenase activity |
GO:0048244 |
2 |
| CXCR3 chemokine receptor binding |
GO:0048248 |
9 |
| Flap endonuclease activity |
GO:0048256 |
7 |
| 3'-flap endonuclease activity |
GO:0048257 |
2 |
| Methionine adenosyltransferase regulator activity |
GO:0048270 |
2 |
| Mitogen-activated protein kinase p38 binding |
GO:0048273 |
1122 |
| Calcium-dependent protein binding |
GO:0048306 |
1880 |
| Rac GTPase binding |
GO:0048365 |
1193 |
| Brain-derived neurotrophic factor binding |
GO:0048403 |
29 |
| Nerve growth factor binding |
GO:0048406 |
19 |
| Platelet-derived growth factor binding |
GO:0048407 |
63 |
| Epidermal growth factor binding |
GO:0048408 |
10 |
| Beta-tubulin binding |
GO:0048487 |
1222 |
| Roundabout binding |
GO:0048495 |
67 |
| Calcium-induced calcium release activity |
GO:0048763 |
233 |
| L-fuconate dehydratase activity |
GO:0050023 |
511 |
| L-pipecolate oxidase activity |
GO:0050031 |
566 |
| Leukotriene-B4 20-monooxygenase activity |
GO:0050051 |
50 |
| Long-chain-aldehyde dehydrogenase activity |
GO:0050061 |
292 |
| M7G(5')pppN diphosphatase activity |
GO:0050072 |
1397 |
| Malonyl-CoA decarboxylase activity |
GO:0050080 |
2 |
| L-gulonate 3-dehydrogenase activity |
GO:0050104 |
1 |
| N-acylneuraminate-9-phosphatase activity |
GO:0050124 |
270 |
| N-formylglutamate deformylase activity |
GO:0050129 |
7 |
| NAD(P)+ nucleosidase activity |
GO:0050135 |
61 |
| Nucleoside phosphate kinase activity |
GO:0050145 |
5 |
| Nucleoside phosphotransferase activity |
GO:0050146 |
644 |
| Fucokinase activity |
GO:0050201 |
4 |
| Procollagen galactosyltransferase activity |
GO:0050211 |
479 |
| Prostaglandin-E synthase activity |
GO:0050220 |
536 |
| Retinol O-fatty-acyltransferase activity |
GO:0050252 |
4 |
| Rhodopsin kinase activity |
GO:0050254 |
3 |
| RNA uridylyltransferase activity |
GO:0050265 |
20 |
| Sphingosine N-acyltransferase activity |
GO:0050291 |
572 |
| Steroid sulfotransferase activity |
GO:0050294 |
248 |
| Tau-protein kinase activity |
GO:0050321 |
1544 |
| Thiamin-triphosphatase activity |
GO:0050333 |
5 |
| Trans-octaprenyltranstransferase activity |
GO:0050347 |
734 |
| Trimethyllysine dioxygenase activity |
GO:0050353 |
1 |
| [acetyl-CoA carboxylase] kinase activity |
GO:0050405 |
918 |
| Calcium-dependent phospholipase C activity |
GO:0050429 |
3 |
| Transforming growth factor beta binding |
GO:0050431 |
1596 |
| Microfibril binding |
GO:0050436 |
3 |
| Arachidonate 15-lipoxygenase activity |
GO:0050473 |
267 |
| Hyaluronan synthase activity |
GO:0050501 |
10 |
| Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
GO:0050508 |
8 |
| N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
GO:0050509 |
3 |
| N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
GO:0050510 |
385 |
| Acyloxyacyl hydrolase activity |
GO:0050528 |
5 |
| Icosatetraenoic acid binding |
GO:0050543 |
4 |
| Arachidonic acid binding |
GO:0050544 |
546 |
| Aspartate-tRNA(Asn) ligase activity |
GO:0050560 |
1 |
| Glutamate-tRNA(Gln) ligase activity |
GO:0050561 |
6 |
| Glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity |
GO:0050567 |
1347 |
| Quinine 3-monooxygenase activity |
GO:0050591 |
374 |
| Methylarsonate reductase activity |
GO:0050610 |
1 |
| Delta14-sterol reductase activity |
GO:0050613 |
4 |
| Delta24-sterol reductase activity |
GO:0050614 |
6 |
| 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding |
GO:0050646 |
2 |
| 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding |
GO:0050647 |
2 |
| 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding |
GO:0050648 |
2 |
| Testosterone 6-beta-hydroxylase activity |
GO:0050649 |
374 |
| 3'-phosphoadenosine 5'-phosphosulfate binding |
GO:0050656 |
1315 |
| N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity |
GO:0050659 |
25 |
| Flavin adenine dinucleotide binding |
GO:0050660 |
4569 |
| NADP binding |
GO:0050661 |
2819 |
| Coenzyme binding |
GO:0050662 |
304 |
| Androgen receptor binding |
GO:0050681 |
2333 |
| AF-2 domain binding |
GO:0050682 |
79 |
| AF-1 domain binding |
GO:0050683 |
1 |
| LBD domain binding |
GO:0050693 |
14 |
| Galactose 3-O-sulfotransferase activity |
GO:0050694 |
664 |
| Proteoglycan sulfotransferase activity |
GO:0050698 |
664 |
| WW domain binding |
GO:0050699 |
2078 |
| CARD domain binding |
GO:0050700 |
2655 |
| RS domain binding |
GO:0050733 |
1288 |
| Low-density lipoprotein particle receptor binding |
GO:0050750 |
2745 |
| Dopamine receptor binding |
GO:0050780 |
1 |
| RAGE receptor binding |
GO:0050786 |
11 |
| GABA receptor binding |
GO:0050811 |
728 |
| Phosphoserine binding |
GO:0050815 |
160 |
| Phosphothreonine binding |
GO:0050816 |
8 |
| Toxin receptor binding |
GO:0050827 |
6 |
| Pyruvate transmembrane transporter activity |
GO:0050833 |
1174 |
| Cell adhesion molecule binding |
GO:0050839 |
3359 |
| Extracellular matrix binding |
GO:0050840 |
336 |
| Cobalt ion binding |
GO:0050897 |
701 |
| Nitric-oxide synthase binding |
GO:0050998 |
1104 |
| Microtubule plus-end binding |
GO:0051010 |
246 |
| Microtubule minus-end binding |
GO:0051011 |
16 |
| Actin filament binding |
GO:0051015 |
4140 |
| Protein kinase A binding |
GO:0051018 |
346 |
| Mitogen-activated protein kinase binding |
GO:0051019 |
114 |
| GTPase binding |
GO:0051020 |
1485 |
| GDP-dissociation inhibitor binding |
GO:0051021 |
3 |
| Rho GDP-dissociation inhibitor binding |
GO:0051022 |
2 |
| RNA transmembrane transporter activity |
GO:0051033 |
230 |
| NF-kappaB binding |
GO:0051059 |
1353 |
| Unfolded protein binding |
GO:0051082 |
4538 |
| Chaperone binding |
GO:0051087 |
3545 |
| ATPase binding |
GO:0051117 |
4412 |
| Hepoxilin A3 synthase activity |
GO:0051120 |
196 |
| Metal ion:hydrogen antiporter activity |
GO:0051139 |
205 |
| Vitamin transporter activity |
GO:0051183 |
4 |
| Dioxygenase activity |
GO:0051213 |
1510 |
| Phosphoprotein binding |
GO:0051219 |
2066 |
| Mono-olein transacylation activity |
GO:0051264 |
557 |
| Diolein transacylation activity |
GO:0051265 |
557 |
| CP2 mannose-ethanolamine phosphotransferase activity |
GO:0051267 |
1 |
| NAD binding |
GO:0051287 |
1917 |
| Muscle alpha-actinin binding |
GO:0051371 |
1577 |
| FATZ binding |
GO:0051373 |
4 |
| Serotonin binding |
GO:0051378 |
527 |
| Epinephrine binding |
GO:0051379 |
29 |
| Norepinephrine binding |
GO:0051380 |
25 |
| Alpha-actinin binding |
GO:0051393 |
1236 |
| BH domain binding |
GO:0051400 |
12 |
| Corticotropin-releasing hormone binding |
GO:0051424 |
6 |
| PTB domain binding |
GO:0051425 |
763 |
| Hormone receptor binding |
GO:0051427 |
1310 |
| Peptide hormone receptor binding |
GO:0051428 |
637 |
| Corticotropin-releasing hormone receptor 1 binding |
GO:0051430 |
11 |
| Corticotropin-releasing hormone receptor 2 binding |
GO:0051431 |
2 |
| BH3 domain binding |
GO:0051434 |
13 |
| BH4 domain binding |
GO:0051435 |
5 |
| NFAT protein binding |
GO:0051525 |
857 |
| Iron-sulfur cluster binding |
GO:0051536 |
2400 |
| 2 iron, 2 sulfur cluster binding |
GO:0051537 |
2764 |
| 4 iron, 4 sulfur cluster binding |
GO:0051539 |
3171 |
| 5'-deoxyribose-5-phosphate lyase activity |
GO:0051575 |
744 |
| Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity |
GO:0051717 |
5 |
| DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates |
GO:0051718 |
2 |
| Protein phosphatase 2A binding |
GO:0051721 |
432 |
| NAD transporter activity |
GO:0051724 |
2 |
| Polynucleotide 5'-hydroxyl-kinase activity |
GO:0051731 |
2308 |
| Polydeoxyribonucleotide kinase activity |
GO:0051733 |
2 |
| ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity |
GO:0051736 |
2 |
| Cytosine C-5 DNA demethylase activity |
GO:0051747 |
3 |
| Misfolded protein binding |
GO:0051787 |
464 |
| Phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity |
GO:0051800 |
5 |
| Glycolipid binding |
GO:0051861 |
17 |
| Histone demethylase activity (H3-K36 specific) |
GO:0051864 |
31 |
| Hsp90 protein binding |
GO:0051879 |
2291 |
| G-quadruplex DNA binding |
GO:0051880 |
215 |
| Double-stranded DNA specific 5'-3' exodeoxyribonuclease activity |
GO:0051908 |
3 |
| Peroxiredoxin activity |
GO:0051920 |
3 |
| Dynein light intermediate chain binding |
GO:0051959 |
6 |
| Squalene synthase activity |
GO:0051996 |
10 |
| Sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity |
GO:0052591 |
6 |
| Tryptamine:oxygen oxidoreductase (deaminating) activity |
GO:0052593 |
5 |
| Aminoacetone:oxygen oxidoreductase(deaminating) activity |
GO:0052594 |
5 |
| Aliphatic-amine oxidase activity |
GO:0052595 |
5 |
| Phenethylamine:oxygen oxidoreductase (deaminating) activity |
GO:0052596 |
5 |
| Phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity |
GO:0052629 |
288 |
| Lysophosphatidic acid phosphatase activity |
GO:0052642 |
283 |
| NADP-retinol dehydrogenase activity |
GO:0052650 |
1068 |
| L-leucine transaminase activity |
GO:0052654 |
13 |
| L-valine transaminase activity |
GO:0052655 |
13 |
| L-isoleucine transaminase activity |
GO:0052656 |
13 |
| Inositol-1,4,5-trisphosphate 5-phosphatase activity |
GO:0052658 |
954 |
| Carboxylic ester hydrolase activity |
GO:0052689 |
769 |
| Inositol-1,3,4-trisphosphate 6-kinase activity |
GO:0052725 |
664 |
| Inositol-1,3,4-trisphosphate 5-kinase activity |
GO:0052726 |
664 |
| Phosphocholine phosphatase activity |
GO:0052731 |
2 |
| Phosphoethanolamine phosphatase activity |
GO:0052732 |
2 |
| (R)-limonene 6-monooxygenase activity |
GO:0052741 |
5 |
| Inositol phosphate phosphatase activity |
GO:0052745 |
6 |
| Exo-alpha-(2->3)-sialidase activity |
GO:0052794 |
3 |
| Exo-alpha-(2->6)-sialidase activity |
GO:0052795 |
3 |
| Exo-alpha-(2->8)-sialidase activity |
GO:0052796 |
3 |
| Beta-galactoside alpha-2,3-sialyltransferase activity |
GO:0052798 |
539 |
| Medium-chain-aldehyde dehydrogenase activity |
GO:0052814 |
292 |
| Medium-chain acyl-CoA hydrolase activity |
GO:0052815 |
3 |
| Long-chain acyl-CoA hydrolase activity |
GO:0052816 |
3 |
| Very long chain acyl-CoA hydrolase activity |
GO:0052817 |
3 |
| Inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity |
GO:0052825 |
664 |
| Inositol hexakisphosphate 2-phosphatase activity |
GO:0052826 |
4 |
| Inositol-1,3,4-trisphosphate 1-phosphatase activity |
GO:0052829 |
2 |
| Inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity |
GO:0052830 |
664 |
| Inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity |
GO:0052831 |
664 |
| Inositol monophosphate 3-phosphatase activity |
GO:0052832 |
969 |
| Inositol monophosphate 4-phosphatase activity |
GO:0052833 |
969 |
| Inositol monophosphate phosphatase activity |
GO:0052834 |
355 |
| Inositol-3,4,6-trisphosphate 1-kinase activity |
GO:0052835 |
664 |
| Inositol diphosphate tetrakisphosphate diphosphatase activity |
GO:0052840 |
52 |
| Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity |
GO:0052843 |
52 |
| Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity |
GO:0052844 |
52 |
| Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity |
GO:0052845 |
52 |
| Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity |
GO:0052846 |
52 |
| Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity |
GO:0052847 |
52 |
| Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity |
GO:0052848 |
52 |
| Ferric-chelate reductase (NADPH) activity |
GO:0052851 |
1207 |
| Very-long-chain-(S)-2-hydroxy-acid oxidase activity |
GO:0052852 |
3 |
| Long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity |
GO:0052853 |
3 |
| Medium-chain-(S)-2-hydroxy-acid oxidase activity |
GO:0052854 |
3 |
| Phosphatidylinositol phosphate phosphatase activity |
GO:0052866 |
273 |
| Arachidonic acid omega-hydroxylase activity |
GO:0052869 |
3 |
| Alpha-tocopherol omega-hydroxylase activity |
GO:0052871 |
45 |
| Tocotrienol omega-hydroxylase activity |
GO:0052872 |
2 |
| All-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity |
GO:0052884 |
5 |
| All-trans-retinyl-ester hydrolase, 11-cis retinol forming activity |
GO:0052885 |
5 |
| N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity |
GO:0052899 |
1 |
| Spermine:oxygen oxidoreductase (spermidine-forming) activity |
GO:0052901 |
1 |
| Spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity |
GO:0052902 |
1 |
| N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity |
GO:0052903 |
1 |
| N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity |
GO:0052904 |
1 |
| Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity |
GO:0052917 |
4 |
| Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity |
GO:0052918 |
745 |
| Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity |
GO:0052926 |
745 |
| D-glucose transmembrane transporter activity |
GO:0055056 |
646 |
| Gap junction hemi-channel activity |
GO:0055077 |
7 |
| Adiponectin binding |
GO:0055100 |
10 |
| Lipase inhibitor activity |
GO:0055102 |
7 |
| Ligase regulator activity |
GO:0055103 |
6 |
| Ubiquitin-protein ligase inhibitor activity |
GO:0055105 |
1 |
| Ubiquitin-protein ligase regulator activity |
GO:0055106 |
8 |
| Minus-end directed microfilament motor activity |
GO:0060001 |
735 |
| Plus-end directed microfilament motor activity |
GO:0060002 |
962 |
| Large conductance calcium-activated potassium channel activity |
GO:0060072 |
22 |
| Binding, bridging |
GO:0060090 |
4 |
| Brain-derived neurotrophic factor-activated receptor activity |
GO:0060175 |
22 |
| Phosphatidylcholine-sterol O-acyltransferase activator activity |
GO:0060228 |
5 |
| Lipase activator activity |
GO:0060229 |
1 |
| Lipoprotein lipase activator activity |
GO:0060230 |
3 |
| Peptidyl-dipeptidase inhibitor activity |
GO:0060422 |
4 |
| Phospholipase D inhibitor activity |
GO:0060961 |
6 |
| Endopeptidase activator activity |
GO:0061133 |
6 |
| NA |
GO:0061507 |
2 |
| NA |
GO:0061547 |
4 |
| NA |
GO:0061578 |
1890 |
| NA |
GO:0061597 |
3 |
| NA |
GO:0061598 |
3 |
| NA |
GO:0061599 |
3 |
| NA |
GO:0061609 |
4 |
| NA |
GO:0061627 |
999 |
| NA |
GO:0061628 |
11 |
| NA |
GO:0061629 |
1 |
| NA |
GO:0061630 |
3568 |
| NA |
GO:0061631 |
1822 |
| NA |
GO:0061649 |
394 |
| Aspartic-type peptidase activity |
GO:0070001 |
4 |
| Glutamic-type peptidase activity |
GO:0070002 |
4 |
| Metalloaminopeptidase activity |
GO:0070006 |
4 |
| Serine-type exopeptidase activity |
GO:0070008 |
523 |
| Serine-type aminopeptidase activity |
GO:0070009 |
7 |
| Oligopeptidase activity |
GO:0070012 |
2 |
| Armadillo repeat domain binding |
GO:0070016 |
71 |
| Nitric oxide binding |
GO:0070026 |
2 |
| Fibrinogen binding |
GO:0070051 |
14 |
| Collagen V binding |
GO:0070052 |
13 |
| Thrombospondin receptor activity |
GO:0070053 |
663 |
| Fructose binding |
GO:0070061 |
11 |
| RNA polymerase binding |
GO:0070063 |
95 |
| Proline-rich region binding |
GO:0070064 |
1505 |
| Titin Z domain binding |
GO:0070080 |
2 |
| Chromo shadow domain binding |
GO:0070087 |
645 |
| Fructose-6-phosphate binding |
GO:0070095 |
2 |
| Delta-catenin binding |
GO:0070097 |
70 |
| Ciliary neurotrophic factor binding |
GO:0070119 |
1356 |
| Transforming growth factor beta receptor activity, type III |
GO:0070123 |
8 |
| DNA polymerase binding |
GO:0070182 |
1478 |
| Phosphatidylinositol-4-phosphate binding |
GO:0070273 |
2595 |
| NAPE-specific phospholipase D activity |
GO:0070290 |
161 |
| Phosphatidic acid binding |
GO:0070300 |
24 |
| Inward rectifier potassium channel inhibitor activity |
GO:0070320 |
7 |
| Thyroid hormone binding |
GO:0070324 |
17 |
| Lipoprotein particle receptor binding |
GO:0070325 |
17 |
| Very-low-density lipoprotein particle receptor binding |
GO:0070326 |
2558 |
| Aromatase activity |
GO:0070330 |
1510 |
| Aspartate binding |
GO:0070335 |
6 |
| Mitochondrial light strand promoter sense binding |
GO:0070363 |
241 |
| NADP+ binding |
GO:0070401 |
1 |
| NADPH binding |
GO:0070402 |
14 |
| NAD+ binding |
GO:0070403 |
940 |
| NADH binding |
GO:0070404 |
6 |
| Co-SMAD binding |
GO:0070410 |
1278 |
| I-SMAD binding |
GO:0070411 |
1131 |
| R-SMAD binding |
GO:0070412 |
1321 |
| Repressing transcription factor binding |
GO:0070491 |
2186 |
| Oligosaccharide binding |
GO:0070492 |
201 |
| Death domain binding |
GO:0070513 |
121 |
| K63-linked polyubiquitin binding |
GO:0070530 |
1667 |
| Oleic acid binding |
GO:0070538 |
12 |
| Linoleic acid binding |
GO:0070539 |
693 |
| Uridylyltransferase activity |
GO:0070569 |
414 |
| Vitamin D 24-hydroxylase activity |
GO:0070576 |
375 |
| Histone acetyl-lysine binding |
GO:0070577 |
933 |
| Methylcytosine dioxygenase activity |
GO:0070579 |
42 |
| Histone methyltransferase activity (H3-R2 specific) |
GO:0070611 |
2 |
| Histone methyltransferase activity (H2A-R3 specific) |
GO:0070612 |
2 |
| (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity |
GO:0070626 |
2 |
| Proteasome binding |
GO:0070628 |
531 |
| Vitamin D response element binding |
GO:0070644 |
424 |
| High-density lipoprotein particle receptor binding |
GO:0070653 |
2 |
| Inositol 1,4,5 trisphosphate binding |
GO:0070679 |
544 |
| Type I activin receptor binding |
GO:0070698 |
3 |
| Type II activin receptor binding |
GO:0070699 |
7 |
| BMP receptor binding |
GO:0070700 |
1136 |
| Leucine binding |
GO:0070728 |
636 |
| Protein-glycine ligase activity |
GO:0070735 |
176 |
| Protein-glycine ligase activity, initiating |
GO:0070736 |
172 |
| C2H2 zinc finger domain binding |
GO:0070742 |
811 |
| Peptidyl-lysine 5-dioxygenase activity |
GO:0070815 |
748 |
| Chromium ion transmembrane transporter activity |
GO:0070835 |
591 |
| Dynein complex binding |
GO:0070840 |
15 |
| Growth factor receptor binding |
GO:0070851 |
19 |
| Myosin VI binding |
GO:0070853 |
405 |
| Myosin VI light chain binding |
GO:0070856 |
7 |
| E-box binding |
GO:0070888 |
2266 |
| Sodium-dependent L-ascorbate transmembrane transporter activity |
GO:0070890 |
24 |
| Lipoteichoic acid binding |
GO:0070891 |
1 |
| Lipoteichoic acid receptor activity |
GO:0070892 |
659 |
| Serine binding |
GO:0070905 |
9 |
| FHA domain binding |
GO:0070975 |
8 |
| TIR domain binding |
GO:0070976 |
2 |
| SnRNP binding |
GO:0070990 |
1 |
| Medium-chain-acyl-CoA dehydrogenase activity |
GO:0070991 |
1 |
| Type 1 melanocortin receptor binding |
GO:0070996 |
5 |
| RNA trimethylguanosine synthase activity |
GO:0071164 |
103 |
| Histone pre-mRNA stem-loop binding |
GO:0071207 |
386 |
| Histone pre-mRNA DCP binding |
GO:0071208 |
925 |
| U7 snRNA binding |
GO:0071209 |
1 |
| Connexin binding |
GO:0071253 |
837 |
| Ankyrin repeat binding |
GO:0071532 |
32 |
| RING-like zinc finger domain binding |
GO:0071535 |
10 |
| Histone demethylase activity (H3-K27 specific) |
GO:0071558 |
564 |
| UFM1 conjugating enzyme activity |
GO:0071568 |
7 |
| Lipopeptide binding |
GO:0071723 |
696 |
| Chemokine (C-C motif) ligand 5 binding |
GO:0071791 |
3 |
| Lipoprotein particle binding |
GO:0071813 |
677 |
| N-box binding |
GO:0071820 |
3 |
| HMG box domain binding |
GO:0071837 |
420 |
| Protein phosphatase type 1 activator activity |
GO:0071862 |
1878 |
| Vitamin D receptor activator activity |
GO:0071884 |
7 |
| 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding |
GO:0071886 |
103 |
| 14-3-3 protein binding |
GO:0071889 |
886 |
| Arp2/3 complex binding |
GO:0071933 |
1073 |
| Coreceptor activity involved in Wnt receptor signaling pathway |
GO:0071936 |
10 |
| FAD binding |
GO:0071949 |
3020 |
| WD40-repeat domain binding |
GO:0071987 |
529 |
| Volume-sensitive chloride channel activity |
GO:0072320 |
275 |
| Modified amino acid binding |
GO:0072341 |
463 |
| NAADP-sensitive calcium-release channel activity |
GO:0072345 |
47 |
| Peroxynitrite reductase activity |
GO:0072541 |
1 |
| Tyrosine binding |
GO:0072545 |
478 |
| Phosphatidylinositol-3,5-bisphosphate binding |
GO:0080025 |
2549 |
| Phosphatidyl-N-dimethylethanolamine N-methyltransferase activity |
GO:0080101 |
1 |
| AMP transmembrane transporter activity |
GO:0080122 |
2 |
| L-phenylalanine:2-oxoglutarate aminotransferase activity |
GO:0080130 |
751 |
| Fatty acid alpha-hydroxylase activity |
GO:0080132 |
4 |
| L-cysteine desulfhydrase activity |
GO:0080146 |
301 |
| Voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential |
GO:0086006 |
1102 |
| Voltage-gated calcium channel activity involved in regulation of cardiac muscle cell action potential |
GO:0086007 |
9 |
| Voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization |
GO:0086008 |
22 |
| Calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential |
GO:0086039 |
40 |
| Voltage-gated calcium channel activity involved in regulation of SA node cardiac muscle cell action potential |
GO:0086059 |
9 |
| Voltage-gated sodium channel activity involved in regulation of Purkinje myocyte action potential |
GO:0086062 |
4 |
| Voltage-gated sodium channel activity involved in regulation of SA node cardiac muscle cell action potential |
GO:0086063 |
14 |
| Gap junction channel activity involved in cardiac conduction electrical coupling |
GO:0086075 |
2 |
| Gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling |
GO:0086077 |
2 |
| Protein binding involved in heterotypic cell-cell adhesion |
GO:0086080 |
158 |
| Voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization |
GO:0086089 |
6 |
| Nicotinate transporter activity |
GO:0090416 |
3 |
| NA |
GO:0090450 |
10 |
| NA |
GO:0090541 |
124 |
| Ceramide binding |
GO:0097001 |
14 |
| L27 domain binding |
GO:0097016 |
702 |
| Ubiquitin-protein ligase activator activity |
GO:0097027 |
7 |
| Supercoiled DNA binding |
GO:0097100 |
3 |
| Hedgehog family protein binding |
GO:0097108 |
23 |
| Neuroligin family protein binding |
GO:0097109 |
1067 |
| Scaffold protein binding |
GO:0097110 |
2625 |
| Cysteine-type endopeptidase activity involved in apoptotic process |
GO:0097153 |
1319 |
| Pre-mRNA intronic binding |
GO:0097157 |
20 |
| Organic cyclic compound binding |
GO:0097159 |
5 |
| DH domain binding |
GO:0097161 |
6 |
| Mitochondrial ribosome binding |
GO:0097177 |
3 |
| Cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
GO:0097199 |
1547 |
| Cysteine-type endopeptidase activity involved in execution phase of apoptosis |
GO:0097200 |
1 |
| Eoxin A4 synthase activity |
GO:0097260 |
191 |
| NA |
GO:0097371 |
1443 |
| NA |
GO:0097372 |
1064 |
| NA |
GO:0097383 |
10 |
| NA |
GO:0097493 |
64 |
| NA |
GO:0097573 |
3 |
| NA |
GO:0097602 |
1593 |
| NA |
GO:0098519 |
160 |
| NA |
GO:0098531 |
24 |
| NA |
GO:0098599 |
32 |
| NA |
GO:0098639 |
748 |
| NA |
GO:0098640 |
1 |
| NA |
GO:1901611 |
2 |
| NA |
GO:1901612 |
661 |
| NA |
GO:1901640 |
10 |
| NA |
GO:1901641 |
10 |
| NA |
GO:1901981 |
24 |
| NA |
GO:1902098 |
415 |
| NA |
GO:1902121 |
415 |
| NA |
GO:1902122 |
126 |
| NA |
GO:1902282 |
20 |
| NA |
GO:1903135 |
1 |
| NA |
GO:1903136 |
1 |
| NA |
GO:1990050 |
729 |
| NA |
GO:1990081 |
1 |
| NA |
GO:1990136 |
1 |
| NA |
GO:1990175 |
2 |
| NA |
GO:1990188 |
1 |
| NA |
GO:1990226 |
16 |
| NA |
GO:1990239 |
680 |
| NA |
GO:1990247 |
8 |
| NA |
GO:1990254 |
10 |
| NA |
GO:1990272 |
1 |
| NA |
GO:1990380 |
1883 |
| NA |
GO:1990381 |
805 |
| NA |
GO:1990422 |
1 |
| NA |
GO:1990430 |
480 |
| NA |
GO:1990444 |
797 |
| NA |
GO:1990450 |
2 |
| NA |
GO:1990459 |
622 |
| NA |
GO:1990460 |
622 |
| Mannan binding |
GO:2001065 |
5 |
| Glycogen binding |
GO:2001069 |
5 |
| Starch binding |
GO:2001070 |
2 |