hsa00590	hsa00860	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	Porphyrin and chlorophyll metabolism - Homo sapiens (human)	BLVRB,HMOX1,CP,UGT1A1,UGT1A10,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A7,UGT1A8,UGT1A9	0.001	ALOX15B-down UGT1A1-up|ALOX15B-down UGT1A3-up|GPX3-down CP-up|PTGDS-up CP-up|GPX3-down HMOX1-down|GPX3-down UGT1A1-up|GPX7-up HMOX1-down|GPX8-up HMOX1-down|PTGDS-up HMOX1-down	ALOX15B-down_247 UGT1A1-up_54658|ALOX15B-down_247 UGT1A3-up_54659|GPX3-down_2878 CP-up_1356|PTGDS-up_5730 CP-up_1356|GPX3-down_2878 HMOX1-down_3162|GPX3-down_2878 UGT1A1-up_54658|GPX7-up_2882 HMOX1-down_3162|GPX8-up_493869 HMOX1-down_3162|PTGDS-up_5730 HMOX1-down_3162
hsa00590	hsa03320	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	0	GPX3-down FABP4-up|GPX3-down SCD-down|GPX7-up SCD-down|PTGDS-up MMP1-up|PLA2G1B-down SCD-down|PTGDS-up SCD-down	GPX3-down_2878 FABP4-up_2167|GPX3-down_2878 SCD-down_6319|GPX7-up_2882 SCD-down_6319|PTGDS-up_5730 MMP1-up_4312|PLA2G1B-down_5319 SCD-down_6319|PTGDS-up_5730 SCD-down_6319
hsa00590	hsa04151	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0.046	ALOX15B-down IGF1-up|ALOX15B-down SPP1-up|GPX3-down COL1A1-up|PTGDS-up COL1A1-up|GPX3-down COL1A2-up|PLA2G1B-down COL1A2-up|PLA2G1B-down CSF3R-down|GPX3-down SPP1-up|GPX3-down THBS1-down|GPX3-down THBS2-up|PLA2G1B-down IGF1-up|PTGDS-up SPP1-up|PTGDS-up TNC-up	ALOX15B-down_247 IGF1-up_3479|ALOX15B-down_247 SPP1-up_6696|GPX3-down_2878 COL1A1-up_1277|PTGDS-up_5730 COL1A1-up_1277|GPX3-down_2878 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|PLA2G1B-down_5319 CSF3R-down_1441|GPX3-down_2878 SPP1-up_6696|GPX3-down_2878 THBS1-down_7057|GPX3-down_2878 THBS2-up_7058|PLA2G1B-down_5319 IGF1-up_3479|PTGDS-up_5730 SPP1-up_6696|PTGDS-up_5730 TNC-up_3371
hsa00590	hsa04510	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0.044	ALOX15B-down IGF1-up|ALOX15B-down SPP1-up|GPX3-down COL1A1-up|PTGDS-up COL1A1-up|GPX3-down COL1A2-up|PLA2G1B-down COL1A2-up|GPX3-down JUN-down|GPX3-down SPP1-up|GPX3-down THBS1-down|GPX3-down THBS2-up|PLA2G1B-down IGF1-up|PTGDS-up JUN-down|PTGDS-up SPP1-up|PTGDS-up TNC-up	ALOX15B-down_247 IGF1-up_3479|ALOX15B-down_247 SPP1-up_6696|GPX3-down_2878 COL1A1-up_1277|PTGDS-up_5730 COL1A1-up_1277|GPX3-down_2878 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|GPX3-down_2878 JUN-down_3725|GPX3-down_2878 SPP1-up_6696|GPX3-down_2878 THBS1-down_7057|GPX3-down_2878 THBS2-up_7058|PLA2G1B-down_5319 IGF1-up_3479|PTGDS-up_5730 JUN-down_3725|PTGDS-up_5730 SPP1-up_6696|PTGDS-up_5730 TNC-up_3371
hsa00590	hsa04512	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	ALOX15B-down SPP1-up|GPX3-down COL1A1-up|PTGDS-up COL1A1-up|GPX3-down COL1A2-up|PLA2G1B-down COL1A2-up|GPX3-down SPP1-up|GPX3-down THBS1-down|GPX3-down THBS2-up|PTGDS-up SPP1-up|PTGDS-up TNC-up	ALOX15B-down_247 SPP1-up_6696|GPX3-down_2878 COL1A1-up_1277|PTGDS-up_5730 COL1A1-up_1277|GPX3-down_2878 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|GPX3-down_2878 SPP1-up_6696|GPX3-down_2878 THBS1-down_7057|GPX3-down_2878 THBS2-up_7058|PTGDS-up_5730 SPP1-up_6696|PTGDS-up_5730 TNC-up_3371
hsa00590	hsa04933	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.033	GPX3-down COL1A1-up|PTGDS-up COL1A1-up|GPX3-down COL1A2-up|PLA2G1B-down COL1A2-up|GPX3-down COL3A1-up|PTGDS-up COL3A1-up|GPX3-down JUN-down|GPX3-down SERPINE1-down|PTGDS-up JUN-down|PTGDS-up SERPINE1-down|PTGDS-up VCAM1-up	GPX3-down_2878 COL1A1-up_1277|PTGDS-up_5730 COL1A1-up_1277|GPX3-down_2878 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|GPX3-down_2878 COL3A1-up_1281|PTGDS-up_5730 COL3A1-up_1281|GPX3-down_2878 JUN-down_3725|GPX3-down_2878 SERPINE1-down_5054|PTGDS-up_5730 JUN-down_3725|PTGDS-up_5730 SERPINE1-down_5054|PTGDS-up_5730 VCAM1-up_7412
hsa00590	hsa04974	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	GPX3-down COL1A1-up|PTGDS-up COL1A1-up|GPX3-down COL1A2-up|PLA2G1B-down COL1A2-up|GPX3-down COL3A1-up|PTGDS-up COL3A1-up|GPX8-up COL5A1-up|PTGDS-up COL5A1-up|GPX8-up COL5A2-up|PLA2G1B-down COL5A2-up|PLA2G1B-down CPA3-up|GPX3-down SLC1A1-down|PTGDS-up MME-down|PLA2G1B-down PRSS1-up	GPX3-down_2878 COL1A1-up_1277|PTGDS-up_5730 COL1A1-up_1277|GPX3-down_2878 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|GPX3-down_2878 COL3A1-up_1281|PTGDS-up_5730 COL3A1-up_1281|GPX8-up_493869 COL5A1-up_1289|PTGDS-up_5730 COL5A1-up_1289|GPX8-up_493869 COL5A2-up_1290|PLA2G1B-down_5319 COL5A2-up_1290|PLA2G1B-down_5319 CPA3-up_1359|GPX3-down_2878 SLC1A1-down_6505|PTGDS-up_5730 MME-down_4311|PLA2G1B-down_5319 PRSS1-up_5644
hsa00590	hsa04978	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0	ALOX15B-down MT1E-down|ALOX15B-down MT2A-down|GPX3-down HMOX1-down|GPX3-down MT1E-down|GPX3-down MT1G-down|GPX3-down MT1X-down|GPX3-down TF-up|GPX7-up HMOX1-down|GPX8-up HMOX1-down|PTGDS-up HMOX1-down|PTGDS-up TF-up	ALOX15B-down_247 MT1E-down_4493|ALOX15B-down_247 MT2A-down_4502|GPX3-down_2878 HMOX1-down_3162|GPX3-down_2878 MT1E-down_4493|GPX3-down_2878 MT1G-down_4495|GPX3-down_2878 MT1X-down_4501|GPX3-down_2878 TF-up_7018|GPX7-up_2882 HMOX1-down_3162|GPX8-up_493869 HMOX1-down_3162|PTGDS-up_5730 HMOX1-down_3162|PTGDS-up_5730 TF-up_7018
hsa00590	hsa05146	Arachidonic acid metabolism - Homo sapiens (human)	ALOX15B,GPX3,PLA2G1B,GPX7,GPX8,PTGDS	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.006	GPX3-down COL1A1-up|PTGDS-up COL1A1-up|GPX3-down COL1A2-up|PLA2G1B-down COL1A2-up|GPX3-down COL3A1-up|PTGDS-up COL3A1-up	GPX3-down_2878 COL1A1-up_1277|PTGDS-up_5730 COL1A1-up_1277|GPX3-down_2878 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|GPX3-down_2878 COL3A1-up_1281|PTGDS-up_5730 COL3A1-up_1281
hsa00860	hsa04152	Porphyrin and chlorophyll metabolism - Homo sapiens (human)	BLVRB,HMOX1,CP,UGT1A1,UGT1A10,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A7,UGT1A8,UGT1A9	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	0.037	BLVRB-down IGF1-up|CP-up CCND1-up|HMOX1-down CCND1-up|UGT1A6-up CCND1-up|CP-up HMGCR-down|CP-up IGF1-up|HMOX1-down FASN-down|HMOX1-down HMGCR-down|UGT1A1-up HMGCR-down|UGT1A6-up HMGCR-down|HMOX1-down IGF1-up|HMOX1-down IRS2-down|HMOX1-down SCD-down	BLVRB-down_645 IGF1-up_3479|CP-up_1356 CCND1-up_595|HMOX1-down_3162 CCND1-up_595|UGT1A6-up_54578 CCND1-up_595|CP-up_1356 HMGCR-down_3156|CP-up_1356 IGF1-up_3479|HMOX1-down_3162 FASN-down_2194|HMOX1-down_3162 HMGCR-down_3156|UGT1A1-up_54658 HMGCR-down_3156|UGT1A6-up_54578 HMGCR-down_3156|HMOX1-down_3162 IGF1-up_3479|HMOX1-down_3162 IRS2-down_8660|HMOX1-down_3162 SCD-down_6319
hsa00860	hsa04610	Porphyrin and chlorophyll metabolism - Homo sapiens (human)	BLVRB,HMOX1,CP,UGT1A1,UGT1A10,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A7,UGT1A8,UGT1A9	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.032	CP-up CFH-up|CP-up F3-down|CP-up SERPIND1-up|CP-up SERPINE1-down|HMOX1-down F3-down|HMOX1-down PLAU-up|HMOX1-down SERPINE1-down|HMOX1-down TFPI-down	CP-up_1356 CFH-up_3075|CP-up_1356 F3-down_2152|CP-up_1356 SERPIND1-up_3053|CP-up_1356 SERPINE1-down_5054|HMOX1-down_3162 F3-down_2152|HMOX1-down_3162 PLAU-up_5328|HMOX1-down_3162 SERPINE1-down_5054|HMOX1-down_3162 TFPI-down_7035
hsa03320	hsa04060	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	0.005	FABP4-up CCL11-up|MMP1-up CCL11-up|MMP1-up CCL13-up|FABP4-up CXCL12-up|MMP1-up CXCL12-up|MMP1-up CXCL13-up|MMP1-up CXCL14-up|PLTP-up CXCL14-up|MMP1-up CXCL2-down|SCD-down CXCL2-down|MMP1-up CXCR2-down|FABP4-up FLT1-down|FABP4-up TGFB3-up|MMP1-up FIGF-down|MMP1-up FLT1-down|MMP1-up PDGFRA-down|MMP1-up TGFB3-up	FABP4-up_2167 CCL11-up_6356|MMP1-up_4312 CCL11-up_6356|MMP1-up_4312 CCL13-up_6357|FABP4-up_2167 CXCL12-up_6387|MMP1-up_4312 CXCL12-up_6387|MMP1-up_4312 CXCL13-up_10563|MMP1-up_4312 CXCL14-up_9547|PLTP-up_5360 CXCL14-up_9547|MMP1-up_4312 CXCL2-down_2920|SCD-down_6319 CXCL2-down_2920|MMP1-up_4312 CXCR2-down_3579|FABP4-up_2167 FLT1-down_2321|FABP4-up_2167 TGFB3-up_7043|MMP1-up_4312 FIGF-down_2277|MMP1-up_4312 FLT1-down_2321|MMP1-up_4312 PDGFRA-down_5156|MMP1-up_4312 TGFB3-up_7043
hsa03320	hsa04062	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	0	FABP4-up CCL11-up|MMP1-up CCL11-up|MMP1-up CCL13-up|FABP4-up CXCL12-up|MMP1-up CXCL12-up|MMP1-up CXCL13-up|MMP1-up CXCL14-up|PLTP-up CXCL14-up|MMP1-up CXCL2-down|SCD-down CXCL2-down|MMP1-up CXCR2-down	FABP4-up_2167 CCL11-up_6356|MMP1-up_4312 CCL11-up_6356|MMP1-up_4312 CCL13-up_6357|FABP4-up_2167 CXCL12-up_6387|MMP1-up_4312 CXCL12-up_6387|MMP1-up_4312 CXCL13-up_10563|MMP1-up_4312 CXCL14-up_9547|PLTP-up_5360 CXCL14-up_9547|MMP1-up_4312 CXCL2-down_2920|SCD-down_6319 CXCL2-down_2920|MMP1-up_4312 CXCR2-down_3579
hsa03320	hsa04064	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	0.001	MMP1-up CCL13-up|FABP4-up CXCL12-up|MMP1-up CXCL12-up|MMP1-up CXCL2-down|SCD-down CXCL2-down|FABP4-up VCAM1-up|MMP1-up PLAU-up|MMP1-up VCAM1-up|PLTP-up VCAM1-up	MMP1-up_4312 CCL13-up_6357|FABP4-up_2167 CXCL12-up_6387|MMP1-up_4312 CXCL12-up_6387|MMP1-up_4312 CXCL2-down_2920|SCD-down_6319 CXCL2-down_2920|FABP4-up_2167 VCAM1-up_7412|MMP1-up_4312 PLAU-up_5328|MMP1-up_4312 VCAM1-up_7412|PLTP-up_5360 VCAM1-up_7412
hsa03320	hsa04068	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	0	ACADL-down IRS2-down|ACADL-down SOD2-down|ACSL1-down IRS2-down|ACSL1-down PRKAA2-up|ACSL1-down SOD2-down|FABP4-up CCND1-up|MMP1-up CCND1-up|SCD-down CCND1-up|MMP1-up CCND2-up|FABP4-up IGF1-up|FABP4-up IRS2-down|FABP4-up PRKAA2-up|FABP4-up TGFB3-up|MMP1-up IGF1-up|SCD-down IGF1-up|SCD-down IRS2-down|MMP1-up S1PR1-down|MMP1-up SOD2-down|MMP1-up TGFB3-up|SCD-down PRKAA2-up	ACADL-down_33 IRS2-down_8660|ACADL-down_33 SOD2-down_6648|ACSL1-down_2180 IRS2-down_8660|ACSL1-down_2180 PRKAA2-up_5563|ACSL1-down_2180 SOD2-down_6648|FABP4-up_2167 CCND1-up_595|MMP1-up_4312 CCND1-up_595|SCD-down_6319 CCND1-up_595|MMP1-up_4312 CCND2-up_894|FABP4-up_2167 IGF1-up_3479|FABP4-up_2167 IRS2-down_8660|FABP4-up_2167 PRKAA2-up_5563|FABP4-up_2167 TGFB3-up_7043|MMP1-up_4312 IGF1-up_3479|SCD-down_6319 IGF1-up_3479|SCD-down_6319 IRS2-down_8660|MMP1-up_4312 S1PR1-down_1901|MMP1-up_4312 SOD2-down_6648|MMP1-up_4312 TGFB3-up_7043|SCD-down_6319 PRKAA2-up_5563
hsa03320	hsa04115	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	0.011	FABP4-up CCND1-up|MMP1-up CCND1-up|SCD-down CCND1-up|MMP1-up CCND2-up|FABP4-up IGF1-up|FABP4-up SERPINE1-down|FABP4-up THBS1-down|MMP1-up IGF1-up|SCD-down IGF1-up|MMP1-up SERPINB5-up|MMP1-up SERPINE1-down|MMP1-up THBS1-down|SCD-down SERPINE1-down|SCD-down THBS1-down	FABP4-up_2167 CCND1-up_595|MMP1-up_4312 CCND1-up_595|SCD-down_6319 CCND1-up_595|MMP1-up_4312 CCND2-up_894|FABP4-up_2167 IGF1-up_3479|FABP4-up_2167 SERPINE1-down_5054|FABP4-up_2167 THBS1-down_7057|MMP1-up_4312 IGF1-up_3479|SCD-down_6319 IGF1-up_3479|MMP1-up_4312 SERPINB5-up_5268|MMP1-up_4312 SERPINE1-down_5054|MMP1-up_4312 THBS1-down_7057|SCD-down_6319 SERPINE1-down_5054|SCD-down_6319 THBS1-down_7057
hsa03320	hsa04151	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0	ACSL1-down COL1A1-up|ACSL1-down COL1A2-up|ACSL1-down PRKAA2-up|FABP4-up CCND1-up|MMP1-up CCND1-up|SCD-down CCND1-up|MMP1-up CCND2-up|FABP4-up COL1A1-up|MMP1-up COL1A1-up|FABP4-up COL1A2-up|MMP1-up COL1A2-up|MMP1-up COL6A1-up|MMP1-up COL6A3-up|MMP1-up COMP-up|FABP4-up FLT1-down|FABP4-up IGF1-up|FABP4-up PRKAA2-up|FABP4-up SPP1-up|FABP4-up THBS1-down|MMP1-up FIGF-down|MMP1-up FLT1-down|MMP1-up IGF1-up|SCD-down IGF1-up|MMP1-up ITGB4-up|MMP1-up JAK1-down|MMP1-up LAMA3-down|MMP1-up MCL1-down|MMP1-up MYB-up|MMP1-up PDGFRA-down|MMP1-up SPP1-up|MMP1-up THBS1-down|MMP1-up THBS2-up|MMP1-up TNC-up|SCD-down PRKAA2-up|SCD-down SPP1-up|SCD-down THBS1-down	ACSL1-down_2180 COL1A1-up_1277|ACSL1-down_2180 COL1A2-up_1278|ACSL1-down_2180 PRKAA2-up_5563|FABP4-up_2167 CCND1-up_595|MMP1-up_4312 CCND1-up_595|SCD-down_6319 CCND1-up_595|MMP1-up_4312 CCND2-up_894|FABP4-up_2167 COL1A1-up_1277|MMP1-up_4312 COL1A1-up_1277|FABP4-up_2167 COL1A2-up_1278|MMP1-up_4312 COL1A2-up_1278|MMP1-up_4312 COL6A1-up_1291|MMP1-up_4312 COL6A3-up_1293|MMP1-up_4312 COMP-up_1311|FABP4-up_2167 FLT1-down_2321|FABP4-up_2167 IGF1-up_3479|FABP4-up_2167 PRKAA2-up_5563|FABP4-up_2167 SPP1-up_6696|FABP4-up_2167 THBS1-down_7057|MMP1-up_4312 FIGF-down_2277|MMP1-up_4312 FLT1-down_2321|MMP1-up_4312 IGF1-up_3479|SCD-down_6319 IGF1-up_3479|MMP1-up_4312 ITGB4-up_3691|MMP1-up_4312 JAK1-down_3716|MMP1-up_4312 LAMA3-down_3909|MMP1-up_4312 MCL1-down_4170|MMP1-up_4312 MYB-up_4602|MMP1-up_4312 PDGFRA-down_5156|MMP1-up_4312 SPP1-up_6696|MMP1-up_4312 THBS1-down_7057|MMP1-up_4312 THBS2-up_7058|MMP1-up_4312 TNC-up_3371|SCD-down_6319 PRKAA2-up_5563|SCD-down_6319 SPP1-up_6696|SCD-down_6319 THBS1-down_7057
hsa03320	hsa04152	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	0	ACADL-down FASN-down|ACADL-down HMGCR-down|ACADL-down IRS2-down|ACADL-down SCD-down|ACSL1-down FASN-down|ACSL1-down HMGCR-down|ACSL1-down IRS2-down|ACSL1-down PRKAA2-up|ACSL1-down SCD-down|FABP4-up CCND1-up|MMP1-up CCND1-up|FABP4-up FASN-down|FABP4-up HMGCR-down|FABP4-up IGF1-up|FABP4-up IRS2-down|FABP4-up PRKAA2-up|PLTP-up FASN-down|MMP1-up HMGCR-down|PLTP-up HMGCR-down|MMP1-up IGF1-up	ACADL-down_33 FASN-down_2194|ACADL-down_33 HMGCR-down_3156|ACADL-down_33 IRS2-down_8660|ACADL-down_33 SCD-down_6319|ACSL1-down_2180 FASN-down_2194|ACSL1-down_2180 HMGCR-down_3156|ACSL1-down_2180 IRS2-down_8660|ACSL1-down_2180 PRKAA2-up_5563|ACSL1-down_2180 SCD-down_6319|FABP4-up_2167 CCND1-up_595|MMP1-up_4312 CCND1-up_595|FABP4-up_2167 FASN-down_2194|FABP4-up_2167 HMGCR-down_3156|FABP4-up_2167 IGF1-up_3479|FABP4-up_2167 IRS2-down_8660|FABP4-up_2167 PRKAA2-up_5563|PLTP-up_5360 FASN-down_2194|MMP1-up_4312 HMGCR-down_3156|PLTP-up_5360 HMGCR-down_3156|MMP1-up_4312 IGF1-up_3479
hsa03320	hsa04213	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	0.009	ACADL-down IRS2-down|ACADL-down SOD2-down|ACSL1-down IRS2-down|ACSL1-down PRKAA2-up|ACSL1-down SOD2-down|FABP4-up IGF1-up|FABP4-up IRS2-down|FABP4-up PRKAA2-up|MMP1-up IGF1-up|SCD-down IGF1-up|SCD-down IRS2-down|MMP1-up SOD2-down|SCD-down PRKAA2-up	ACADL-down_33 IRS2-down_8660|ACADL-down_33 SOD2-down_6648|ACSL1-down_2180 IRS2-down_8660|ACSL1-down_2180 PRKAA2-up_5563|ACSL1-down_2180 SOD2-down_6648|FABP4-up_2167 IGF1-up_3479|FABP4-up_2167 IRS2-down_8660|FABP4-up_2167 PRKAA2-up_5563|MMP1-up_4312 IGF1-up_3479|SCD-down_6319 IGF1-up_3479|SCD-down_6319 IRS2-down_8660|MMP1-up_4312 SOD2-down_6648|SCD-down_6319 PRKAA2-up_5563
hsa03320	hsa04350	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0.003	FABP4-up TGFB3-up|FABP4-up THBS1-down|MMP1-up ID1-down|MMP1-up LTBP1-up|MMP1-up SMAD6-down|MMP1-up TGFB3-up|MMP1-up THBS1-down|SCD-down THBS1-down	FABP4-up_2167 TGFB3-up_7043|FABP4-up_2167 THBS1-down_7057|MMP1-up_4312 ID1-down_3397|MMP1-up_4312 LTBP1-up_4052|MMP1-up_4312 SMAD6-down_4091|MMP1-up_4312 TGFB3-up_7043|MMP1-up_4312 THBS1-down_7057|SCD-down_6319 THBS1-down_7057
hsa03320	hsa04510	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0.002	ACSL1-down COL1A1-up|ACSL1-down COL1A2-up|ACSL1-down JUN-down|FABP4-up CCND1-up|MMP1-up CCND1-up|SCD-down CCND1-up|MMP1-up CCND2-up|FABP4-up COL1A1-up|MMP1-up COL1A1-up|FABP4-up COL1A2-up|MMP1-up COL1A2-up|MMP1-up COL6A1-up|MMP1-up COL6A3-up|MMP1-up COMP-up|FABP4-up FLT1-down|FABP4-up IGF1-up|FABP4-up JUN-down|FABP4-up SPP1-up|FABP4-up THBS1-down|MMP1-up FIGF-down|MMP1-up FLT1-down|MMP1-up IGF1-up|SCD-down IGF1-up|MMP1-up ITGB4-up|MMP1-up JUN-down|SCD-down JUN-down|MMP1-up LAMA3-down|MMP1-up PDGFRA-down|MMP1-up SPP1-up|MMP1-up THBS1-down|MMP1-up THBS2-up|MMP1-up TNC-up|SCD-down SPP1-up|SCD-down THBS1-down	ACSL1-down_2180 COL1A1-up_1277|ACSL1-down_2180 COL1A2-up_1278|ACSL1-down_2180 JUN-down_3725|FABP4-up_2167 CCND1-up_595|MMP1-up_4312 CCND1-up_595|SCD-down_6319 CCND1-up_595|MMP1-up_4312 CCND2-up_894|FABP4-up_2167 COL1A1-up_1277|MMP1-up_4312 COL1A1-up_1277|FABP4-up_2167 COL1A2-up_1278|MMP1-up_4312 COL1A2-up_1278|MMP1-up_4312 COL6A1-up_1291|MMP1-up_4312 COL6A3-up_1293|MMP1-up_4312 COMP-up_1311|FABP4-up_2167 FLT1-down_2321|FABP4-up_2167 IGF1-up_3479|FABP4-up_2167 JUN-down_3725|FABP4-up_2167 SPP1-up_6696|FABP4-up_2167 THBS1-down_7057|MMP1-up_4312 FIGF-down_2277|MMP1-up_4312 FLT1-down_2321|MMP1-up_4312 IGF1-up_3479|SCD-down_6319 IGF1-up_3479|MMP1-up_4312 ITGB4-up_3691|MMP1-up_4312 JUN-down_3725|SCD-down_6319 JUN-down_3725|MMP1-up_4312 LAMA3-down_3909|MMP1-up_4312 PDGFRA-down_5156|MMP1-up_4312 SPP1-up_6696|MMP1-up_4312 THBS1-down_7057|MMP1-up_4312 THBS2-up_7058|MMP1-up_4312 TNC-up_3371|SCD-down_6319 SPP1-up_6696|SCD-down_6319 THBS1-down_7057
hsa03320	hsa04512	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	ACSL1-down COL1A1-up|ACSL1-down COL1A2-up|FABP4-up COL1A1-up|MMP1-up COL1A1-up|FABP4-up COL1A2-up|MMP1-up COL1A2-up|MMP1-up COL6A1-up|MMP1-up COL6A3-up|MMP1-up COMP-up|FABP4-up SPP1-up|FABP4-up THBS1-down|MMP1-up ITGB4-up|MMP1-up LAMA3-down|MMP1-up SPP1-up|MMP1-up THBS1-down|MMP1-up THBS2-up|MMP1-up TNC-up|SCD-down SPP1-up|SCD-down THBS1-down	ACSL1-down_2180 COL1A1-up_1277|ACSL1-down_2180 COL1A2-up_1278|FABP4-up_2167 COL1A1-up_1277|MMP1-up_4312 COL1A1-up_1277|FABP4-up_2167 COL1A2-up_1278|MMP1-up_4312 COL1A2-up_1278|MMP1-up_4312 COL6A1-up_1291|MMP1-up_4312 COL6A3-up_1293|MMP1-up_4312 COMP-up_1311|FABP4-up_2167 SPP1-up_6696|FABP4-up_2167 THBS1-down_7057|MMP1-up_4312 ITGB4-up_3691|MMP1-up_4312 LAMA3-down_3909|MMP1-up_4312 SPP1-up_6696|MMP1-up_4312 THBS1-down_7057|MMP1-up_4312 THBS2-up_7058|MMP1-up_4312 TNC-up_3371|SCD-down_6319 SPP1-up_6696|SCD-down_6319 THBS1-down_7057
hsa03320	hsa04514	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0.017	MMP1-up CDH2-up|MMP1-up CLDN1-up|MMP1-up CLDN5-down|FABP4-up VCAM1-up|MMP1-up NCAM1-up|MMP1-up VCAM1-up|PLTP-up VCAM1-up	MMP1-up_4312 CDH2-up_1000|MMP1-up_4312 CLDN1-up_9076|MMP1-up_4312 CLDN5-down_7122|FABP4-up_2167 VCAM1-up_7412|MMP1-up_4312 NCAM1-up_4684|MMP1-up_4312 VCAM1-up_7412|PLTP-up_5360 VCAM1-up_7412
hsa03320	hsa04610	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.045	ACSL1-down TFPI-down|FABP4-up SERPINE1-down|MMP1-up PLAU-up|MMP1-up SERPINE1-down|MMP1-up TFPI-down|SCD-down SERPINE1-down	ACSL1-down_2180 TFPI-down_7035|FABP4-up_2167 SERPINE1-down_5054|MMP1-up_4312 PLAU-up_5328|MMP1-up_4312 SERPINE1-down_5054|MMP1-up_4312 TFPI-down_7035|SCD-down_6319 SERPINE1-down_5054
hsa03320	hsa04668	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.001	ACSL1-down JUN-down|MMP1-up CXCL2-down|SCD-down CXCL2-down|FABP4-up JUN-down|FABP4-up SOCS3-down|FABP4-up VCAM1-up|MMP1-up JUN-down|SCD-down JUN-down|MMP1-up SOCS3-down|MMP1-up VCAM1-up|PLTP-up VCAM1-up|SCD-down SOCS3-down	ACSL1-down_2180 JUN-down_3725|MMP1-up_4312 CXCL2-down_2920|SCD-down_6319 CXCL2-down_2920|FABP4-up_2167 JUN-down_3725|FABP4-up_2167 SOCS3-down_9021|FABP4-up_2167 VCAM1-up_7412|MMP1-up_4312 JUN-down_3725|SCD-down_6319 JUN-down_3725|MMP1-up_4312 SOCS3-down_9021|MMP1-up_4312 VCAM1-up_7412|PLTP-up_5360 VCAM1-up_7412|SCD-down_6319 SOCS3-down_9021
hsa03320	hsa04670	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0.009	MMP1-up CLDN1-up|MMP1-up CLDN5-down|FABP4-up CXCL12-up|MMP1-up CXCL12-up|FABP4-up VCAM1-up|MMP1-up MMP2-up|MMP1-up VCAM1-up|PLTP-up VCAM1-up	MMP1-up_4312 CLDN1-up_9076|MMP1-up_4312 CLDN5-down_7122|FABP4-up_2167 CXCL12-up_6387|MMP1-up_4312 CXCL12-up_6387|FABP4-up_2167 VCAM1-up_7412|MMP1-up_4312 MMP2-up_4313|MMP1-up_4312 VCAM1-up_7412|PLTP-up_5360 VCAM1-up_7412
hsa03320	hsa04933	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.001	ACSL1-down COL1A1-up|ACSL1-down COL1A2-up|ACSL1-down COL3A1-up|ACSL1-down JUN-down|FABP4-up CCND1-up|MMP1-up CCND1-up|SCD-down CCND1-up|FABP4-up COL1A1-up|MMP1-up COL1A1-up|FABP4-up COL1A2-up|MMP1-up COL1A2-up|FABP4-up COL3A1-up|MMP1-up COL3A1-up|FABP4-up JUN-down|FABP4-up SERPINE1-down|FABP4-up TGFB3-up|FABP4-up VCAM1-up|MMP1-up FIGF-down|MMP1-up JUN-down|SCD-down JUN-down|MMP1-up MMP2-up|MMP1-up SERPINE1-down|MMP1-up TGFB3-up|MMP1-up VCAM1-up|PLTP-up VCAM1-up|SCD-down SERPINE1-down	ACSL1-down_2180 COL1A1-up_1277|ACSL1-down_2180 COL1A2-up_1278|ACSL1-down_2180 COL3A1-up_1281|ACSL1-down_2180 JUN-down_3725|FABP4-up_2167 CCND1-up_595|MMP1-up_4312 CCND1-up_595|SCD-down_6319 CCND1-up_595|FABP4-up_2167 COL1A1-up_1277|MMP1-up_4312 COL1A1-up_1277|FABP4-up_2167 COL1A2-up_1278|MMP1-up_4312 COL1A2-up_1278|FABP4-up_2167 COL3A1-up_1281|MMP1-up_4312 COL3A1-up_1281|FABP4-up_2167 JUN-down_3725|FABP4-up_2167 SERPINE1-down_5054|FABP4-up_2167 TGFB3-up_7043|FABP4-up_2167 VCAM1-up_7412|MMP1-up_4312 FIGF-down_2277|MMP1-up_4312 JUN-down_3725|SCD-down_6319 JUN-down_3725|MMP1-up_4312 MMP2-up_4313|MMP1-up_4312 SERPINE1-down_5054|MMP1-up_4312 TGFB3-up_7043|MMP1-up_4312 VCAM1-up_7412|PLTP-up_5360 VCAM1-up_7412|SCD-down_6319 SERPINE1-down_5054
hsa03320	hsa04974	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	ACSL1-down COL14A1-up|ACSL1-down COL1A1-up|ACSL1-down COL1A2-up|ACSL1-down COL3A1-up|ACSL1-down CPA3-up|MMP1-up COL10A1-up|MMP1-up COL14A1-up|FABP4-up COL15A1-up|MMP1-up COL17A1-up|MMP1-up COL18A1-up|FABP4-up COL1A1-up|MMP1-up COL1A1-up|FABP4-up COL1A2-up|MMP1-up COL1A2-up|FABP4-up COL3A1-up|MMP1-up COL3A1-up|MMP1-up COL5A1-up|MMP1-up COL5A2-up|SCD-down COL5A2-up|MMP1-up COL6A1-up|MMP1-up COL6A3-up|MMP1-up COL7A1-up|MMP1-up MME-down|MMP1-up PRSS1-up	ACSL1-down_2180 COL14A1-up_7373|ACSL1-down_2180 COL1A1-up_1277|ACSL1-down_2180 COL1A2-up_1278|ACSL1-down_2180 COL3A1-up_1281|ACSL1-down_2180 CPA3-up_1359|MMP1-up_4312 COL10A1-up_1300|MMP1-up_4312 COL14A1-up_7373|FABP4-up_2167 COL15A1-up_1306|MMP1-up_4312 COL17A1-up_1308|MMP1-up_4312 COL18A1-up_80781|FABP4-up_2167 COL1A1-up_1277|MMP1-up_4312 COL1A1-up_1277|FABP4-up_2167 COL1A2-up_1278|MMP1-up_4312 COL1A2-up_1278|FABP4-up_2167 COL3A1-up_1281|MMP1-up_4312 COL3A1-up_1281|MMP1-up_4312 COL5A1-up_1289|MMP1-up_4312 COL5A2-up_1290|SCD-down_6319 COL5A2-up_1290|MMP1-up_4312 COL6A1-up_1291|MMP1-up_4312 COL6A3-up_1293|MMP1-up_4312 COL7A1-up_1294|MMP1-up_4312 MME-down_4311|MMP1-up_4312 PRSS1-up_5644
hsa03320	hsa04978	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.004	ACSL1-down TF-up|FABP4-up HMOX1-down|FABP4-up TF-up|MMP1-up HMOX1-down|SCD-down HMOX1-down|MMP1-up TF-up|SCD-down TF-up	ACSL1-down_2180 TF-up_7018|FABP4-up_2167 HMOX1-down_3162|FABP4-up_2167 TF-up_7018|MMP1-up_4312 HMOX1-down_3162|SCD-down_6319 HMOX1-down_3162|MMP1-up_4312 TF-up_7018|SCD-down_6319 TF-up_7018
hsa03320	hsa05145	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.042	FABP4-up LDLR-down|FABP4-up TGFB3-up|MMP1-up JAK1-down|MMP1-up LAMA3-down|MMP1-up LDLR-down|PLTP-up LDLR-down|SCD-down LDLR-down|MMP1-up TGFB3-up	FABP4-up_2167 LDLR-down_3949|FABP4-up_2167 TGFB3-up_7043|MMP1-up_4312 JAK1-down_3716|MMP1-up_4312 LAMA3-down_3909|MMP1-up_4312 LDLR-down_3949|PLTP-up_5360 LDLR-down_3949|SCD-down_6319 LDLR-down_3949|MMP1-up_4312 TGFB3-up_7043
hsa03320	hsa05146	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	ACSL1-down COL1A1-up|ACSL1-down COL1A2-up|ACSL1-down COL3A1-up|FABP4-up COL1A1-up|MMP1-up COL1A1-up|FABP4-up COL1A2-up|MMP1-up COL1A2-up|FABP4-up COL3A1-up|MMP1-up COL3A1-up|FABP4-up TGFB3-up|MMP1-up LAMA3-down|MMP1-up TGFB3-up	ACSL1-down_2180 COL1A1-up_1277|ACSL1-down_2180 COL1A2-up_1278|ACSL1-down_2180 COL3A1-up_1281|FABP4-up_2167 COL1A1-up_1277|MMP1-up_4312 COL1A1-up_1277|FABP4-up_2167 COL1A2-up_1278|MMP1-up_4312 COL1A2-up_1278|FABP4-up_2167 COL3A1-up_1281|MMP1-up_4312 COL3A1-up_1281|FABP4-up_2167 TGFB3-up_7043|MMP1-up_4312 LAMA3-down_3909|MMP1-up_4312 TGFB3-up_7043
hsa03320	hsa05160	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0	MMP1-up CLDN1-up|MMP1-up CLDN5-down|FABP4-up LDLR-down|FABP4-up SOCS3-down|MMP1-up JAK1-down|MMP1-up LDLR-down|PLTP-up LDLR-down|SCD-down LDLR-down|MMP1-up SOCS3-down|SCD-down SOCS3-down	MMP1-up_4312 CLDN1-up_9076|MMP1-up_4312 CLDN5-down_7122|FABP4-up_2167 LDLR-down_3949|FABP4-up_2167 SOCS3-down_9021|MMP1-up_4312 JAK1-down_3716|MMP1-up_4312 LDLR-down_3949|PLTP-up_5360 LDLR-down_3949|SCD-down_6319 LDLR-down_3949|MMP1-up_4312 SOCS3-down_9021|SCD-down_6319 SOCS3-down_9021
hsa03320	hsa05206	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.001	ACADL-down IRS2-down|ACSL1-down IRS2-down|FABP4-up CCND1-up|MMP1-up CCND1-up|SCD-down CCND1-up|MMP1-up CCND2-up|SCD-down CYP24A1-up|FABP4-up HMOX1-down|FABP4-up IRS2-down|FABP4-up THBS1-down|MMP1-up HMOX1-down|SCD-down HMOX1-down|SCD-down IRS2-down|MMP1-up MCL1-down|MMP1-up PDGFRA-down|MMP1-up PLAU-up|MMP1-up SERPINB5-up|MMP1-up THBS1-down|MMP1-up TNC-up|SCD-down THBS1-down	ACADL-down_33 IRS2-down_8660|ACSL1-down_2180 IRS2-down_8660|FABP4-up_2167 CCND1-up_595|MMP1-up_4312 CCND1-up_595|SCD-down_6319 CCND1-up_595|MMP1-up_4312 CCND2-up_894|SCD-down_6319 CYP24A1-up_1591|FABP4-up_2167 HMOX1-down_3162|FABP4-up_2167 IRS2-down_8660|FABP4-up_2167 THBS1-down_7057|MMP1-up_4312 HMOX1-down_3162|SCD-down_6319 HMOX1-down_3162|SCD-down_6319 IRS2-down_8660|MMP1-up_4312 MCL1-down_4170|MMP1-up_4312 PDGFRA-down_5156|MMP1-up_4312 PLAU-up_5328|MMP1-up_4312 SERPINB5-up_5268|MMP1-up_4312 THBS1-down_7057|MMP1-up_4312 TNC-up_3371|SCD-down_6319 THBS1-down_7057
hsa03320	hsa05410	PPAR signaling pathway - Homo sapiens (human)	ACADL,ACSL1,SCD,FABP4,MMP1,PLTP	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.036	ACSL1-down PRKAA2-up|FABP4-up IGF1-up|FABP4-up PRKAA2-up|FABP4-up TGFB3-up|MMP1-up IGF1-up|SCD-down IGF1-up|MMP1-up ITGB4-up|MMP1-up TGFB3-up|SCD-down PRKAA2-up	ACSL1-down_2180 PRKAA2-up_5563|FABP4-up_2167 IGF1-up_3479|FABP4-up_2167 PRKAA2-up_5563|FABP4-up_2167 TGFB3-up_7043|MMP1-up_4312 IGF1-up_3479|SCD-down_6319 IGF1-up_3479|MMP1-up_4312 ITGB4-up_3691|MMP1-up_4312 TGFB3-up_7043|SCD-down_6319 PRKAA2-up_5563
hsa04010	hsa04014	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	0.038	ARRB1-down FLT1-down|ARRB1-down IGF1-up|ARRB1-down PDGFRA-down|BDNF-down FGF14-up|BDNF-down FIGF-down|BDNF-down FLT1-down|BDNF-down IGF1-up|BDNF-down PDGFRA-down|DUSP1-down FLT1-down|DUSP1-down IGF1-up|DUSP1-down PDGFRA-down|JUN-down FIGF-down|TGFB3-up FIGF-down|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JUN-down FLT1-down|TGFB3-up FLT1-down|HSPA1A-down IGF1-up|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|TGFB3-up IGF1-up|JUN-down PDGFRA-down|MAP3K8-down PDGFRA-down	ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 PDGFRA-down_5156|BDNF-down_627 FGF14-up_2259|BDNF-down_627 FIGF-down_2277|BDNF-down_627 FLT1-down_2321|BDNF-down_627 IGF1-up_3479|BDNF-down_627 PDGFRA-down_5156|DUSP1-down_1843 FLT1-down_2321|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 PDGFRA-down_5156|JUN-down_3725 FIGF-down_2277|TGFB3-up_7043 FIGF-down_2277|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JUN-down_3725 PDGFRA-down_5156|MAP3K8-down_1326 PDGFRA-down_5156
hsa04010	hsa04015	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	0.01	ARRB1-down FLT1-down|ARRB1-down FPR1-down|ARRB1-down IGF1-up|ARRB1-down PDGFRA-down|BDNF-down FGF14-up|BDNF-down FIGF-down|BDNF-down FLT1-down|BDNF-down IGF1-up|BDNF-down PDGFRA-down|BDNF-down THBS1-down|DUSP1-down FLT1-down|DUSP1-down ID1-down|DUSP1-down IGF1-up|DUSP1-down PDGFRA-down|DUSP1-down THBS1-down|JUN-down FIGF-down|TGFB3-up FIGF-down|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JUN-down FLT1-down|TGFB3-up FLT1-down|GADD45B-down THBS1-down|HSPA1A-down IGF1-up|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|JUN-down ID1-down|TGFB3-up ID1-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|TGFB3-up IGF1-up|JUN-down PDGFRA-down|JUN-down THBS1-down|MAP3K8-down PDGFRA-down|TGFB3-up THBS1-down	ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 FPR1-down_2357|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 PDGFRA-down_5156|BDNF-down_627 FGF14-up_2259|BDNF-down_627 FIGF-down_2277|BDNF-down_627 FLT1-down_2321|BDNF-down_627 IGF1-up_3479|BDNF-down_627 PDGFRA-down_5156|BDNF-down_627 THBS1-down_7057|DUSP1-down_1843 FLT1-down_2321|DUSP1-down_1843 ID1-down_3397|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 PDGFRA-down_5156|DUSP1-down_1843 THBS1-down_7057|JUN-down_3725 FIGF-down_2277|TGFB3-up_7043 FIGF-down_2277|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|GADD45B-down_4616 THBS1-down_7057|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|JUN-down_3725 ID1-down_3397|TGFB3-up_7043 ID1-down_3397|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 THBS1-down_7057|MAP3K8-down_1326 PDGFRA-down_5156|TGFB3-up_7043 THBS1-down_7057
hsa04010	hsa04060	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	0	ARRB1-down CCL11-up|ARRB1-down CXCL12-up|ARRB1-down CXCL2-down|ARRB1-down CXCR2-down|ARRB1-down FLT1-down|ARRB1-down PDGFRA-down|ARRB1-down TGFB3-up|BDNF-down CCL11-up|BDNF-down CXCL12-up|BDNF-down CXCL13-up|BDNF-down FIGF-down|BDNF-down FLT1-down|BDNF-down LIFR-down|BDNF-down PDGFRA-down|BDNF-down TGFB3-up|BDNF-down TNFRSF21-up|JUN-down CCL11-up|DUSP1-down CD27-up|JUN-down CD27-up|JUN-down CSF3R-down|DUSP1-down CXCL12-up|GADD45B-down CXCL12-up|JUN-down CXCL12-up|NTRK2-up CXCL12-up|JUN-down CXCL14-up|DUSP1-down CXCL2-down|GADD45B-down CXCL2-down|HSPA1A-down CXCL2-down|JUN-down CXCL2-down|MAP3K8-down CXCL2-down|JUN-down CXCL3-down|MAP3K8-down CXCL3-down|GADD45B-down CXCR2-down|JUN-down CXCR2-down|DUSP1-down FLT1-down|DUSP1-down PDGFRA-down|FGF14-up FLT1-down|FGF14-up TGFB3-up|JUN-down FIGF-down|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JUN-down FLT1-down|GADD45B-down IL18R1-down|GADD45B-down IL18RAP-down|GADD45B-down IL1R2-down|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|JUN-down IL18R1-down|MAP3K8-down IL18R1-down|JUN-down IL18RAP-down|JUN-down LIFR-down|JUN-down PDGFRA-down|JUN-down TGFB3-up|JUN-down TNFRSF21-up|NTRK2-up LIFR-down|MAP3K8-down PDGFRA-down	ARRB1-down_408 CCL11-up_6356|ARRB1-down_408 CXCL12-up_6387|ARRB1-down_408 CXCL2-down_2920|ARRB1-down_408 CXCR2-down_3579|ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 TGFB3-up_7043|BDNF-down_627 CCL11-up_6356|BDNF-down_627 CXCL12-up_6387|BDNF-down_627 CXCL13-up_10563|BDNF-down_627 FIGF-down_2277|BDNF-down_627 FLT1-down_2321|BDNF-down_627 LIFR-down_3977|BDNF-down_627 PDGFRA-down_5156|BDNF-down_627 TGFB3-up_7043|BDNF-down_627 TNFRSF21-up_27242|JUN-down_3725 CCL11-up_6356|DUSP1-down_1843 CD27-up_939|JUN-down_3725 CD27-up_939|JUN-down_3725 CSF3R-down_1441|DUSP1-down_1843 CXCL12-up_6387|GADD45B-down_4616 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|NTRK2-up_4915 CXCL12-up_6387|JUN-down_3725 CXCL14-up_9547|DUSP1-down_1843 CXCL2-down_2920|GADD45B-down_4616 CXCL2-down_2920|HSPA1A-down_3303 CXCL2-down_2920|JUN-down_3725 CXCL2-down_2920|MAP3K8-down_1326 CXCL2-down_2920|JUN-down_3725 CXCL3-down_2921|MAP3K8-down_1326 CXCL3-down_2921|GADD45B-down_4616 CXCR2-down_3579|JUN-down_3725 CXCR2-down_3579|DUSP1-down_1843 FLT1-down_2321|DUSP1-down_1843 PDGFRA-down_5156|FGF14-up_2259 FLT1-down_2321|FGF14-up_2259 TGFB3-up_7043|JUN-down_3725 FIGF-down_2277|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|GADD45B-down_4616 IL18R1-down_8809|GADD45B-down_4616 IL18RAP-down_8807|GADD45B-down_4616 IL1R2-down_7850|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|JUN-down_3725 IL18R1-down_8809|MAP3K8-down_1326 IL18R1-down_8809|JUN-down_3725 IL18RAP-down_8807|JUN-down_3725 LIFR-down_3977|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TNFRSF21-up_27242|NTRK2-up_4915 LIFR-down_3977|MAP3K8-down_1326 PDGFRA-down_5156
hsa04010	hsa04062	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	0.042	BDNF-down CCL11-up|BDNF-down CXCL12-up|BDNF-down CXCL13-up|JUN-down CCL11-up|DUSP1-down CXCL12-up|GADD45B-down CXCL12-up|JUN-down CXCL12-up|NTRK2-up CXCL12-up|PDGFRA-down CXCL12-up|TGFB3-up CXCL12-up|JUN-down CXCL14-up|DUSP1-down CXCL2-down|GADD45B-down CXCL2-down|HSPA1A-down CXCL2-down|IL1R2-down CXCL2-down|JUN-down CXCL2-down|MAP3K8-down CXCL2-down|JUN-down CXCL3-down|MAP3K8-down CXCL3-down|GADD45B-down CXCR2-down|IL1R2-down CXCR2-down|JUN-down CXCR2-down	BDNF-down_627 CCL11-up_6356|BDNF-down_627 CXCL12-up_6387|BDNF-down_627 CXCL13-up_10563|JUN-down_3725 CCL11-up_6356|DUSP1-down_1843 CXCL12-up_6387|GADD45B-down_4616 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|NTRK2-up_4915 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|JUN-down_3725 CXCL14-up_9547|DUSP1-down_1843 CXCL2-down_2920|GADD45B-down_4616 CXCL2-down_2920|HSPA1A-down_3303 CXCL2-down_2920|IL1R2-down_7850 CXCL2-down_2920|JUN-down_3725 CXCL2-down_2920|MAP3K8-down_1326 CXCL2-down_2920|JUN-down_3725 CXCL3-down_2921|MAP3K8-down_1326 CXCL3-down_2921|GADD45B-down_4616 CXCR2-down_3579|IL1R2-down_7850 CXCR2-down_3579|JUN-down_3725 CXCR2-down_3579
hsa04010	hsa04064	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	0.005	ARRB1-down CXCL12-up|ARRB1-down CXCL2-down|BDNF-down CXCL12-up|BDNF-down GADD45B-down|BDNF-down PLAU-up|BDNF-down VCAM1-up|DUSP1-down CXCL12-up|JUN-down CXCL12-up|NTRK2-up CXCL12-up|PDGFRA-down CXCL12-up|TGFB3-up CXCL12-up|DUSP1-down CXCL2-down|HSPA1A-down CXCL2-down|IL1R2-down CXCL2-down|JUN-down CXCL2-down|MAP3K8-down CXCL2-down|DUSP1-down GADD45B-down|DUSP1-down VCAM1-up|FLNC-up VCAM1-up|JUN-down PLAU-up|JUN-down VCAM1-up|MAP3K8-down PLAU-up|PDGFRA-down PLAU-up|PDGFRA-down VCAM1-up|TGFB3-up PLAU-up|TGFB3-up VCAM1-up	ARRB1-down_408 CXCL12-up_6387|ARRB1-down_408 CXCL2-down_2920|BDNF-down_627 CXCL12-up_6387|BDNF-down_627 GADD45B-down_4616|BDNF-down_627 PLAU-up_5328|BDNF-down_627 VCAM1-up_7412|DUSP1-down_1843 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|NTRK2-up_4915 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|DUSP1-down_1843 CXCL2-down_2920|HSPA1A-down_3303 CXCL2-down_2920|IL1R2-down_7850 CXCL2-down_2920|JUN-down_3725 CXCL2-down_2920|MAP3K8-down_1326 CXCL2-down_2920|DUSP1-down_1843 GADD45B-down_4616|DUSP1-down_1843 VCAM1-up_7412|FLNC-up_2318 VCAM1-up_7412|JUN-down_3725 PLAU-up_5328|JUN-down_3725 VCAM1-up_7412|MAP3K8-down_1326 PLAU-up_5328|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 VCAM1-up_7412
hsa04010	hsa04068	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	0.009	ARRB1-down CCND1-up|ARRB1-down IGF1-up|ARRB1-down S1PR1-down|ARRB1-down TGFB3-up|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down GADD45B-down|BDNF-down IGF1-up|BDNF-down IRS2-down|BDNF-down TGFB3-up|DUSP1-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|DUSP1-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|PDGFRA-down CCND2-up|DUSP1-down FBXO32-up|DUSP1-down GADD45B-down|DUSP1-down IGF1-up|DUSP1-down IRS2-down|DUSP1-down PRKAA2-up|JUN-down FBXO32-up|FGF14-up TGFB3-up|HSPA1A-down IGF1-up|HSPA1A-down SOD2-down|HSPA1B-down SOD2-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|PDGFRA-down IGF1-up|JUN-down IRS2-down|PDGFRA-down IRS2-down|JUN-down PRKAA2-up|JUN-down S1PR1-down|JUN-down SOD2-down|JUN-down TGFB3-up|MAP3K8-down PRKAA2-up|MAP3K8-down SOD2-down|PDGFRA-down S1PR1-down|PDGFRA-down TGFB3-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 S1PR1-down_1901|ARRB1-down_408 TGFB3-up_7043|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 GADD45B-down_4616|BDNF-down_627 IGF1-up_3479|BDNF-down_627 IRS2-down_8660|BDNF-down_627 TGFB3-up_7043|DUSP1-down_1843 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|DUSP1-down_1843 FBXO32-up_114907|DUSP1-down_1843 GADD45B-down_4616|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 IRS2-down_8660|DUSP1-down_1843 PRKAA2-up_5563|JUN-down_3725 FBXO32-up_114907|FGF14-up_2259 TGFB3-up_7043|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 SOD2-down_6648|HSPA1B-down_3304 SOD2-down_6648|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|JUN-down_3725 IRS2-down_8660|PDGFRA-down_5156 IRS2-down_8660|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 S1PR1-down_1901|JUN-down_3725 SOD2-down_6648|JUN-down_3725 TGFB3-up_7043|MAP3K8-down_1326 PRKAA2-up_5563|MAP3K8-down_1326 SOD2-down_6648|PDGFRA-down_5156 S1PR1-down_1901|PDGFRA-down_5156 TGFB3-up_7043
hsa04010	hsa04115	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	0.014	ARRB1-down CCND1-up|ARRB1-down IGF1-up|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down GADD45B-down|BDNF-down IGF1-up|BDNF-down SERPINE1-down|BDNF-down THBS1-down|DUSP1-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|DUSP1-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|DUSP1-down GADD45B-down|DUSP1-down IGF1-up|DUSP1-down SERPINE1-down|DUSP1-down THBS1-down|HSPA1A-down IGF1-up|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|JUN-down PMAIP1-down|JUN-down SERPINB5-up|JUN-down SERPINE1-down|JUN-down THBS1-down|MAP3K8-down SERPINE1-down|PDGFRA-down THBS1-down|TGFB3-up SERPINE1-down|TGFB3-up THBS1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 IGF1-up_3479|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 GADD45B-down_4616|BDNF-down_627 IGF1-up_3479|BDNF-down_627 SERPINE1-down_5054|BDNF-down_627 THBS1-down_7057|DUSP1-down_1843 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|DUSP1-down_1843 GADD45B-down_4616|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 SERPINE1-down_5054|DUSP1-down_1843 THBS1-down_7057|HSPA1A-down_3303 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JUN-down_3725 PMAIP1-down_5366|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SERPINE1-down_5054|JUN-down_3725 THBS1-down_7057|MAP3K8-down_1326 SERPINE1-down_5054|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 SERPINE1-down_5054|TGFB3-up_7043 THBS1-down_7057
hsa04010	hsa04151	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0	ARRB1-down CCND1-up|ARRB1-down FLT1-down|ARRB1-down IGF1-up|ARRB1-down JAK1-down|ARRB1-down PDGFRA-down|ARRB1-down SPP1-up|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down FGF14-up|BDNF-down FIGF-down|BDNF-down FLT1-down|BDNF-down IGF1-up|BDNF-down JAK1-down|BDNF-down MCL1-down|BDNF-down PDGFRA-down|BDNF-down SPP1-up|BDNF-down THBS1-down|BDNF-down TNC-up|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|TGFB3-up CCND1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|TGFB3-up CCND2-up|HSPA1A-down COL1A1-up|JUN-down COL1A1-up|TGFB3-up COL1A1-up|JUN-down COL1A2-up|TGFB3-up COL1A2-up|JUN-down COL6A1-up|TGFB3-up COL6A1-up|JUN-down COL6A3-up|TGFB3-up COL6A3-up|JUN-down COMP-up|TGFB3-up COMP-up|JUN-down CSF3R-down|DUSP1-down FLT1-down|DUSP1-down IGF1-up|DUSP1-down JAK1-down|DUSP1-down MCL1-down|DUSP1-down MYB-up|DUSP1-down PDGFRA-down|DUSP1-down PRKAA2-up|DUSP1-down SPP1-up|DUSP1-down THBS1-down|DUSP1-down THBS2-up|JUN-down FIGF-down|TGFB3-up FIGF-down|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up MYB-up|FLNC-up TNC-up|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JUN-down FLT1-down|TGFB3-up FLT1-down|GADD45B-down JAK1-down|GADD45B-down MCL1-down|GADD45B-down MYB-up|GADD45B-down THBS1-down|HSPA1A-down IGF1-up|HSPA1A-down JAK1-down|HSPA1A-down PDGFRA-down|HSPA1B-down JAK1-down|HSPA1B-down PDGFRA-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|TGFB3-up IGF1-up|IL1R2-down SPP1-up|JUN-down ITGB4-up|TGFB3-up ITGB8-up|JUN-down JAK1-down|JUN-down LAMA3-down|JUN-down MCL1-down|JUN-down MYB-up|JUN-down PDGFRA-down|JUN-down PRKAA2-up|JUN-down SPP1-up|JUN-down THBS1-down|JUN-down THBS2-up|JUN-down TNC-up|MAP3K8-down MCL1-down|MAP3K8-down MYB-up|MAP3K8-down PDGFRA-down|MAP3K8-down PRKAA2-up|NTRK2-up TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 SPP1-up_6696|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 FGF14-up_2259|BDNF-down_627 FIGF-down_2277|BDNF-down_627 FLT1-down_2321|BDNF-down_627 IGF1-up_3479|BDNF-down_627 JAK1-down_3716|BDNF-down_627 MCL1-down_4170|BDNF-down_627 PDGFRA-down_5156|BDNF-down_627 SPP1-up_6696|BDNF-down_627 THBS1-down_7057|BDNF-down_627 TNC-up_3371|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|HSPA1A-down_3303 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|JUN-down_3725 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|JUN-down_3725 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|JUN-down_3725 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|JUN-down_3725 CSF3R-down_1441|DUSP1-down_1843 FLT1-down_2321|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 JAK1-down_3716|DUSP1-down_1843 MCL1-down_4170|DUSP1-down_1843 MYB-up_4602|DUSP1-down_1843 PDGFRA-down_5156|DUSP1-down_1843 PRKAA2-up_5563|DUSP1-down_1843 SPP1-up_6696|DUSP1-down_1843 THBS1-down_7057|DUSP1-down_1843 THBS2-up_7058|JUN-down_3725 FIGF-down_2277|TGFB3-up_7043 FIGF-down_2277|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 MYB-up_4602|FLNC-up_2318 TNC-up_3371|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 MYB-up_4602|GADD45B-down_4616 THBS1-down_7057|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 JAK1-down_3716|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 JAK1-down_3716|HSPA1B-down_3304 PDGFRA-down_5156|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|IL1R2-down_7850 SPP1-up_6696|JUN-down_3725 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 JAK1-down_3716|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MYB-up_4602|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 SPP1-up_6696|JUN-down_3725 THBS1-down_7057|JUN-down_3725 THBS2-up_7058|JUN-down_3725 TNC-up_3371|MAP3K8-down_1326 MCL1-down_4170|MAP3K8-down_1326 MYB-up_4602|MAP3K8-down_1326 PDGFRA-down_5156|MAP3K8-down_1326 PRKAA2-up_5563|NTRK2-up_4915 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04010	hsa04310	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	ARRB1-down CCND1-up|ARRB1-down FZD5-down|ARRB1-down JUN-down|ARRB1-down SFRP2-up|ARRB1-down SFRP4-up|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down JUN-down|BDNF-down MMP7-up|BDNF-down SERPINF1-up|BDNF-down TCF7L2-up|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|DUSP1-down JUN-down|DUSP1-down SERPINF1-up|FGF14-up FZD5-down|FGF14-up SFRP4-up|FGF14-up TCF7L2-up|MAP3K8-down FZD5-down|NTRK2-up FZD5-down|PDGFRA-down FZD5-down|GADD45B-down JUN-down|HSPA1A-down JUN-down|HSPA1B-down JUN-down|NTRK2-up MMP7-up|NTRK2-up SERPINF1-up|NTRK2-up SFRP2-up|NTRK2-up SFRP4-up|PDGFRA-down SFRP2-up|PDGFRA-down SFRP4-up|PDGFRA-down TCF7L2-up|TGFB3-up SFRP2-up|TGFB3-up SFRP4-up|TGFB3-up TCF7L2-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 SFRP2-up_6423|ARRB1-down_408 SFRP4-up_6424|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 JUN-down_3725|BDNF-down_627 MMP7-up_4316|BDNF-down_627 SERPINF1-up_5176|BDNF-down_627 TCF7L2-up_6934|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|DUSP1-down_1843 JUN-down_3725|DUSP1-down_1843 SERPINF1-up_5176|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 SFRP4-up_6424|FGF14-up_2259 TCF7L2-up_6934|MAP3K8-down_1326 FZD5-down_7855|NTRK2-up_4915 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|GADD45B-down_4616 JUN-down_3725|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|NTRK2-up_4915 MMP7-up_4316|NTRK2-up_4915 SERPINF1-up_5176|NTRK2-up_4915 SFRP2-up_6423|NTRK2-up_4915 SFRP4-up_6424|PDGFRA-down_5156 SFRP2-up_6423|PDGFRA-down_5156 SFRP4-up_6424|PDGFRA-down_5156 TCF7L2-up_6934|TGFB3-up_7043 SFRP2-up_6423|TGFB3-up_7043 SFRP4-up_6424|TGFB3-up_7043 TCF7L2-up_6934
hsa04010	hsa04360	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0.021	ARRB1-down CXCL12-up|ARRB1-down NTN1-up|BDNF-down CXCL12-up|BDNF-down EPHA3-up|BDNF-down NTN1-up|BDNF-down ROBO2-up|JUN-down BOC-up|DUSP1-down CXCL12-up|GADD45B-down CXCL12-up|JUN-down CXCL12-up|NTRK2-up CXCL12-up|PDGFRA-down CXCL12-up|TGFB3-up CXCL12-up|DUSP1-down EPHA3-up|DUSP1-down RND1-down|HSPA1A-down EPHA3-up|HSPA1B-down EPHA3-up|JUN-down EPHA3-up|PDGFRA-down EPHA3-up|JUN-down NTN1-up|JUN-down RND1-down|MAP3K8-down RND1-down|NTRK2-up NTN1-up|PDGFRA-down NTN1-up|TGFB3-up NTN1-up|NTRK2-up SEMA3E-down|PDGFRA-down RND1-down|PDGFRA-down ROBO2-up	ARRB1-down_408 CXCL12-up_6387|ARRB1-down_408 NTN1-up_9423|BDNF-down_627 CXCL12-up_6387|BDNF-down_627 EPHA3-up_2042|BDNF-down_627 NTN1-up_9423|BDNF-down_627 ROBO2-up_6092|JUN-down_3725 BOC-up_91653|DUSP1-down_1843 CXCL12-up_6387|GADD45B-down_4616 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|NTRK2-up_4915 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|DUSP1-down_1843 EPHA3-up_2042|DUSP1-down_1843 RND1-down_27289|HSPA1A-down_3303 EPHA3-up_2042|HSPA1B-down_3304 EPHA3-up_2042|JUN-down_3725 EPHA3-up_2042|PDGFRA-down_5156 EPHA3-up_2042|JUN-down_3725 NTN1-up_9423|JUN-down_3725 RND1-down_27289|MAP3K8-down_1326 RND1-down_27289|NTRK2-up_4915 NTN1-up_9423|PDGFRA-down_5156 NTN1-up_9423|TGFB3-up_7043 NTN1-up_9423|NTRK2-up_4915 SEMA3E-down_9723|PDGFRA-down_5156 RND1-down_27289|PDGFRA-down_5156 ROBO2-up_6092
hsa04010	hsa04390	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0	ARRB1-down CCND1-up|ARRB1-down FZD5-down|ARRB1-down TGFB3-up|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down SERPINE1-down|BDNF-down SOX2-up|BDNF-down TCF7L2-up|BDNF-down TGFB3-up|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|PDGFRA-down CCND2-up|DUSP1-down ID1-down|DUSP1-down SERPINE1-down|FGF14-up FZD5-down|FGF14-up TCF7L2-up|FGF14-up TGFB3-up|JUN-down FZD5-down|MAP3K8-down FZD5-down|NTRK2-up FZD5-down|PDGFRA-down FZD5-down|GADD45B-down SERPINE1-down|JUN-down ID1-down|PDGFRA-down ID1-down|JUN-down SERPINE1-down|JUN-down SOX2-up|JUN-down TCF7L2-up|JUN-down TGFB3-up|MAP3K8-down SERPINE1-down|PDGFRA-down SOX2-up|PDGFRA-down TCF7L2-up|PDGFRA-down TGFB3-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 TGFB3-up_7043|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 SERPINE1-down_5054|BDNF-down_627 SOX2-up_6657|BDNF-down_627 TCF7L2-up_6934|BDNF-down_627 TGFB3-up_7043|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|DUSP1-down_1843 ID1-down_3397|DUSP1-down_1843 SERPINE1-down_5054|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TCF7L2-up_6934|FGF14-up_2259 TGFB3-up_7043|JUN-down_3725 FZD5-down_7855|MAP3K8-down_1326 FZD5-down_7855|NTRK2-up_4915 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|GADD45B-down_4616 SERPINE1-down_5054|JUN-down_3725 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|JUN-down_3725 SERPINE1-down_5054|JUN-down_3725 SOX2-up_6657|JUN-down_3725 TCF7L2-up_6934|JUN-down_3725 TGFB3-up_7043|MAP3K8-down_1326 SERPINE1-down_5054|PDGFRA-down_5156 SOX2-up_6657|PDGFRA-down_5156 TCF7L2-up_6934|PDGFRA-down_5156 TGFB3-up_7043
hsa04010	hsa04510	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0.001	ARRB1-down CCND1-up|ARRB1-down FLNC-up|ARRB1-down FLT1-down|ARRB1-down IGF1-up|ARRB1-down JUN-down|ARRB1-down PDGFRA-down|ARRB1-down SPP1-up|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down FIGF-down|BDNF-down FLT1-down|BDNF-down IGF1-up|BDNF-down JUN-down|BDNF-down PDGFRA-down|BDNF-down SPP1-up|BDNF-down THBS1-down|BDNF-down TNC-up|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|TGFB3-up CCND1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|TGFB3-up CCND2-up|HSPA1A-down COL1A1-up|TGFB3-up COL1A1-up|TGFB3-up COL1A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|TGFB3-up COMP-up|DUSP1-down FLT1-down|DUSP1-down IGF1-up|DUSP1-down JUN-down|DUSP1-down PDGFRA-down|DUSP1-down SPP1-up|DUSP1-down THBS1-down|DUSP1-down THBS2-up|FGF14-up FLT1-down|TGFB3-up FIGF-down|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|TGFB3-up FLT1-down|GADD45B-down JUN-down|GADD45B-down THBS1-down|HSPA1A-down IGF1-up|HSPA1A-down JUN-down|HSPA1A-down PDGFRA-down|HSPA1B-down JUN-down|HSPA1B-down PDGFRA-down|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|TGFB3-up IGF1-up|IL1R2-down SPP1-up|TGFB3-up ITGB8-up|MAP3K8-down PDGFRA-down|NTRK2-up TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FLNC-up_2318|ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 SPP1-up_6696|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 FIGF-down_2277|BDNF-down_627 FLT1-down_2321|BDNF-down_627 IGF1-up_3479|BDNF-down_627 JUN-down_3725|BDNF-down_627 PDGFRA-down_5156|BDNF-down_627 SPP1-up_6696|BDNF-down_627 THBS1-down_7057|BDNF-down_627 TNC-up_3371|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|HSPA1A-down_3303 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|TGFB3-up_7043 COL1A2-up_1278|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|TGFB3-up_7043 COMP-up_1311|DUSP1-down_1843 FLT1-down_2321|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 JUN-down_3725|DUSP1-down_1843 PDGFRA-down_5156|DUSP1-down_1843 SPP1-up_6696|DUSP1-down_1843 THBS1-down_7057|DUSP1-down_1843 THBS2-up_7058|FGF14-up_2259 FLT1-down_2321|TGFB3-up_7043 FIGF-down_2277|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 THBS1-down_7057|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 JUN-down_3725|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 JUN-down_3725|HSPA1B-down_3304 PDGFRA-down_5156|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|IL1R2-down_7850 SPP1-up_6696|TGFB3-up_7043 ITGB8-up_3696|MAP3K8-down_1326 PDGFRA-down_5156|NTRK2-up_4915 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04010	hsa04512	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0.001	NTRK2-up AGRN-up|ARRB1-down SPP1-up|BDNF-down SPP1-up|BDNF-down THBS1-down|BDNF-down TNC-up|HSPA1A-down COL1A1-up|JUN-down COL1A1-up|PDGFRA-down COL1A1-up|TGFB3-up COL1A1-up|JUN-down COL1A2-up|PDGFRA-down COL1A2-up|TGFB3-up COL1A2-up|JUN-down COL6A1-up|PDGFRA-down COL6A1-up|TGFB3-up COL6A1-up|JUN-down COL6A3-up|PDGFRA-down COL6A3-up|TGFB3-up COL6A3-up|JUN-down COMP-up|TGFB3-up COMP-up|DUSP1-down SPP1-up|DUSP1-down THBS1-down|DUSP1-down THBS2-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TNC-up|GADD45B-down THBS1-down|IL1R2-down SPP1-up|JUN-down ITGB4-up|PDGFRA-down ITGB4-up|TGFB3-up ITGB8-up|JUN-down LAMA3-down|JUN-down SPP1-up|JUN-down THBS1-down|JUN-down THBS2-up|JUN-down TNC-up|NTRK2-up TNC-up|PDGFRA-down SPP1-up|PDGFRA-down THBS1-down|PDGFRA-down TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	NTRK2-up_4915 AGRN-up_375790|ARRB1-down_408 SPP1-up_6696|BDNF-down_627 SPP1-up_6696|BDNF-down_627 THBS1-down_7057|BDNF-down_627 TNC-up_3371|HSPA1A-down_3303 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|JUN-down_3725 COL6A1-up_1291|PDGFRA-down_5156 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|JUN-down_3725 COL6A3-up_1293|PDGFRA-down_5156 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|JUN-down_3725 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|DUSP1-down_1843 SPP1-up_6696|DUSP1-down_1843 THBS1-down_7057|DUSP1-down_1843 THBS2-up_7058|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TNC-up_3371|GADD45B-down_4616 THBS1-down_7057|IL1R2-down_7850 SPP1-up_6696|JUN-down_3725 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SPP1-up_6696|JUN-down_3725 THBS1-down_7057|JUN-down_3725 THBS2-up_7058|JUN-down_3725 TNC-up_3371|NTRK2-up_4915 TNC-up_3371|PDGFRA-down_5156 SPP1-up_6696|PDGFRA-down_5156 THBS1-down_7057|PDGFRA-down_5156 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04010	hsa04514	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0.004	ARRB1-down CD274-down|BDNF-down CDH2-up|BDNF-down CLDN5-down|BDNF-down NCAM1-up|BDNF-down NFASC-up|BDNF-down VCAM1-up|PDGFRA-down CD274-down|JUN-down CDH2-up|MAP3K8-down CDH2-up|NTRK2-up CDH2-up|PDGFRA-down CDH2-up|TGFB3-up CDH2-up|GADD45B-down CLDN1-up|JUN-down CLDN5-down|DUSP1-down VCAM1-up|FGF14-up NFASC-up|FLNC-up ITGB8-up|FLNC-up VCAM1-up|GADD45B-down VCAM1-up|TGFB3-up ITGB8-up|JUN-down NCAM1-up|JUN-down SELL-down|JUN-down VCAM1-up|MAP3K8-down NCAM1-up|NTRK2-up NCAM1-up|PDGFRA-down NCAM1-up|TGFB3-up NCAM1-up|PDGFRA-down VCAM1-up|TGFB3-up VCAM1-up	ARRB1-down_408 CD274-down_29126|BDNF-down_627 CDH2-up_1000|BDNF-down_627 CLDN5-down_7122|BDNF-down_627 NCAM1-up_4684|BDNF-down_627 NFASC-up_23114|BDNF-down_627 VCAM1-up_7412|PDGFRA-down_5156 CD274-down_29126|JUN-down_3725 CDH2-up_1000|MAP3K8-down_1326 CDH2-up_1000|NTRK2-up_4915 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|GADD45B-down_4616 CLDN1-up_9076|JUN-down_3725 CLDN5-down_7122|DUSP1-down_1843 VCAM1-up_7412|FGF14-up_2259 NFASC-up_23114|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 VCAM1-up_7412|GADD45B-down_4616 VCAM1-up_7412|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 NCAM1-up_4684|JUN-down_3725 SELL-down_6402|JUN-down_3725 VCAM1-up_7412|MAP3K8-down_1326 NCAM1-up_4684|NTRK2-up_4915 NCAM1-up_4684|PDGFRA-down_5156 NCAM1-up_4684|TGFB3-up_7043 NCAM1-up_4684|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04010	hsa04550	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0	ARRB1-down FZD5-down|ARRB1-down IGF1-up|ARRB1-down JAK1-down|BDNF-down IGF1-up|BDNF-down JAK1-down|BDNF-down LIFR-down|BDNF-down SOX2-up|DUSP1-down ID1-down|DUSP1-down IGF1-up|DUSP1-down JAK1-down|FGF14-up FZD5-down|JUN-down FZD5-down|MAP3K8-down FZD5-down|NTRK2-up FZD5-down|PDGFRA-down FZD5-down|GADD45B-down JAK1-down|HSPA1A-down IGF1-up|HSPA1A-down JAK1-down|HSPA1B-down JAK1-down|JUN-down ID1-down|PDGFRA-down ID1-down|TGFB3-up ID1-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|JUN-down JAK1-down|PDGFRA-down JAK1-down|JUN-down LIFR-down|JUN-down SOX2-up|NTRK2-up LIFR-down|PDGFRA-down SOX2-up	ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JAK1-down_3716|BDNF-down_627 IGF1-up_3479|BDNF-down_627 JAK1-down_3716|BDNF-down_627 LIFR-down_3977|BDNF-down_627 SOX2-up_6657|DUSP1-down_1843 ID1-down_3397|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 JAK1-down_3716|FGF14-up_2259 FZD5-down_7855|JUN-down_3725 FZD5-down_7855|MAP3K8-down_1326 FZD5-down_7855|NTRK2-up_4915 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|GADD45B-down_4616 JAK1-down_3716|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 JAK1-down_3716|HSPA1B-down_3304 JAK1-down_3716|JUN-down_3725 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|TGFB3-up_7043 ID1-down_3397|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JUN-down_3725 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|JUN-down_3725 LIFR-down_3977|JUN-down_3725 SOX2-up_6657|NTRK2-up_4915 LIFR-down_3977|PDGFRA-down_5156 SOX2-up_6657
hsa04010	hsa04610	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.008	BDNF-down PLAU-up|BDNF-down SERPINE1-down|JUN-down CFH-up|PDGFRA-down CFH-up|DUSP1-down F3-down|DUSP1-down SERPINE1-down|FLNC-up F3-down|HSPA1A-down F3-down|IL1R2-down F3-down|JUN-down F3-down|PDGFRA-down F3-down|FLNC-up TFPI-down|GADD45B-down PLAU-up|GADD45B-down SERPINE1-down|JUN-down PLAU-up|JUN-down SERPINE1-down|JUN-down TFPI-down|MAP3K8-down PLAU-up|MAP3K8-down SERPINE1-down|PDGFRA-down PLAU-up|TGFB3-up PLAU-up|TGFB3-up SERPINE1-down	BDNF-down_627 PLAU-up_5328|BDNF-down_627 SERPINE1-down_5054|JUN-down_3725 CFH-up_3075|PDGFRA-down_5156 CFH-up_3075|DUSP1-down_1843 F3-down_2152|DUSP1-down_1843 SERPINE1-down_5054|FLNC-up_2318 F3-down_2152|HSPA1A-down_3303 F3-down_2152|IL1R2-down_7850 F3-down_2152|JUN-down_3725 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FLNC-up_2318 TFPI-down_7035|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 SERPINE1-down_5054|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINE1-down_5054|JUN-down_3725 TFPI-down_7035|MAP3K8-down_1326 PLAU-up_5328|MAP3K8-down_1326 SERPINE1-down_5054|PDGFRA-down_5156 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SERPINE1-down_5054
hsa04010	hsa04630	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0	ARRB1-down CCND1-up|ARRB1-down JAK1-down|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down JAK1-down|BDNF-down LIFR-down|BDNF-down MCL1-down|BDNF-down SOCS3-down|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|JUN-down CSF3R-down|DUSP1-down JAK1-down|DUSP1-down MCL1-down|DUSP1-down SOCS3-down|GADD45B-down JAK1-down|GADD45B-down MCL1-down|GADD45B-down SOCS3-down|HSPA1A-down JAK1-down|HSPA1B-down JAK1-down|IL1R2-down SOCS3-down|JUN-down JAK1-down|PDGFRA-down JAK1-down|JUN-down LIFR-down|JUN-down MCL1-down|JUN-down SOCS3-down|NTRK2-up LIFR-down|MAP3K8-down MCL1-down|MAP3K8-down SOCS3-down|PDGFRA-down MCL1-down|PDGFRA-down SOCS3-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 JAK1-down_3716|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 JAK1-down_3716|BDNF-down_627 LIFR-down_3977|BDNF-down_627 MCL1-down_4170|BDNF-down_627 SOCS3-down_9021|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|JUN-down_3725 CSF3R-down_1441|DUSP1-down_1843 JAK1-down_3716|DUSP1-down_1843 MCL1-down_4170|DUSP1-down_1843 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 SOCS3-down_9021|HSPA1A-down_3303 JAK1-down_3716|HSPA1B-down_3304 JAK1-down_3716|IL1R2-down_7850 SOCS3-down_9021|JUN-down_3725 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|JUN-down_3725 LIFR-down_3977|JUN-down_3725 MCL1-down_4170|JUN-down_3725 SOCS3-down_9021|NTRK2-up_4915 LIFR-down_3977|MAP3K8-down_1326 MCL1-down_4170|MAP3K8-down_1326 SOCS3-down_9021|PDGFRA-down_5156 MCL1-down_4170|PDGFRA-down_5156 SOCS3-down_9021
hsa04010	hsa04668	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	ARRB1-down CXCL2-down|ARRB1-down JUN-down|BDNF-down JUN-down|BDNF-down SOCS3-down|BDNF-down VCAM1-up|DUSP1-down CXCL2-down|GADD45B-down CXCL2-down|HSPA1A-down CXCL2-down|IL1R2-down CXCL2-down|DUSP1-down JUN-down|DUSP1-down MAP3K8-down|DUSP1-down SOCS3-down|DUSP1-down VCAM1-up|FLNC-up VCAM1-up|GADD45B-down IL18R1-down|GADD45B-down JUN-down|GADD45B-down MAP3K8-down|GADD45B-down SOCS3-down|GADD45B-down VCAM1-up|HSPA1A-down JUN-down|HSPA1B-down JUN-down|IL1R2-down IL18R1-down|IL1R2-down SOCS3-down|PDGFRA-down SOCS3-down|PDGFRA-down VCAM1-up|TGFB3-up VCAM1-up	ARRB1-down_408 CXCL2-down_2920|ARRB1-down_408 JUN-down_3725|BDNF-down_627 JUN-down_3725|BDNF-down_627 SOCS3-down_9021|BDNF-down_627 VCAM1-up_7412|DUSP1-down_1843 CXCL2-down_2920|GADD45B-down_4616 CXCL2-down_2920|HSPA1A-down_3303 CXCL2-down_2920|IL1R2-down_7850 CXCL2-down_2920|DUSP1-down_1843 JUN-down_3725|DUSP1-down_1843 MAP3K8-down_1326|DUSP1-down_1843 SOCS3-down_9021|DUSP1-down_1843 VCAM1-up_7412|FLNC-up_2318 VCAM1-up_7412|GADD45B-down_4616 IL18R1-down_8809|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MAP3K8-down_1326|GADD45B-down_4616 SOCS3-down_9021|GADD45B-down_4616 VCAM1-up_7412|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|IL1R2-down_7850 IL18R1-down_8809|IL1R2-down_7850 SOCS3-down_9021|PDGFRA-down_5156 SOCS3-down_9021|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04010	hsa04670	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	ARRB1-down CXCL12-up|BDNF-down CLDN5-down|BDNF-down CXCL12-up|BDNF-down MMP2-up|BDNF-down THY1-up|BDNF-down VCAM1-up|GADD45B-down CLDN1-up|JUN-down CLDN5-down|DUSP1-down CXCL12-up|GADD45B-down CXCL12-up|JUN-down CXCL12-up|NTRK2-up CXCL12-up|PDGFRA-down CXCL12-up|TGFB3-up CXCL12-up|DUSP1-down MMP2-up|DUSP1-down VCAM1-up|FLNC-up VCAM1-up|GADD45B-down MMP2-up|GADD45B-down VCAM1-up|JUN-down MMP2-up|JUN-down THY1-up|JUN-down VCAM1-up|NTRK2-up MMP2-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down VCAM1-up|TGFB3-up THY1-up|TGFB3-up VCAM1-up	ARRB1-down_408 CXCL12-up_6387|BDNF-down_627 CLDN5-down_7122|BDNF-down_627 CXCL12-up_6387|BDNF-down_627 MMP2-up_4313|BDNF-down_627 THY1-up_7070|BDNF-down_627 VCAM1-up_7412|GADD45B-down_4616 CLDN1-up_9076|JUN-down_3725 CLDN5-down_7122|DUSP1-down_1843 CXCL12-up_6387|GADD45B-down_4616 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|NTRK2-up_4915 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|DUSP1-down_1843 MMP2-up_4313|DUSP1-down_1843 VCAM1-up_7412|FLNC-up_2318 VCAM1-up_7412|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 VCAM1-up_7412|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THY1-up_7070|JUN-down_3725 VCAM1-up_7412|NTRK2-up_4915 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 THY1-up_7070|TGFB3-up_7043 VCAM1-up_7412
hsa04010	hsa04915	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.028	ARRB1-down GABBR2-up|ARRB1-down JUN-down|ARRB1-down KCNJ5-up|BDNF-down GABBR2-up|BDNF-down HBEGF-down|BDNF-down HSPA1A-down|BDNF-down JUN-down|BDNF-down KCNJ5-up|BDNF-down MMP2-up|DUSP1-down HBEGF-down|DUSP1-down JUN-down|DUSP1-down MMP2-up|NTRK2-up GABBR2-up|GADD45B-down HBEGF-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|IL1R2-down HBEGF-down|MAP3K8-down HBEGF-down|NTRK2-up HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|NTRK2-up KCNJ5-up|NTRK2-up MMP2-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up	ARRB1-down_408 GABBR2-up_9568|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 KCNJ5-up_3762|BDNF-down_627 GABBR2-up_9568|BDNF-down_627 HBEGF-down_1839|BDNF-down_627 HSPA1A-down_3303|BDNF-down_627 JUN-down_3725|BDNF-down_627 KCNJ5-up_3762|BDNF-down_627 MMP2-up_4313|DUSP1-down_1843 HBEGF-down_1839|DUSP1-down_1843 JUN-down_3725|DUSP1-down_1843 MMP2-up_4313|NTRK2-up_4915 GABBR2-up_9568|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|IL1R2-down_7850 HBEGF-down_1839|MAP3K8-down_1326 HBEGF-down_1839|NTRK2-up_4915 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|NTRK2-up_4915 KCNJ5-up_3762|NTRK2-up_4915 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313
hsa04010	hsa04933	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.003	ARRB1-down CCND1-up|ARRB1-down JUN-down|ARRB1-down TGFB3-up|BDNF-down CCND1-up|BDNF-down FIGF-down|BDNF-down JUN-down|BDNF-down MMP2-up|BDNF-down SERPINE1-down|BDNF-down TGFB3-up|BDNF-down VCAM1-up|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|HSPA1A-down COL1A1-up|PDGFRA-down COL1A1-up|PDGFRA-down COL1A2-up|HSPA1A-down COL3A1-up|PDGFRA-down COL3A1-up|DUSP1-down F3-down|DUSP1-down JUN-down|DUSP1-down MMP2-up|DUSP1-down SERPINE1-down|DUSP1-down VCAM1-up|FLNC-up F3-down|HSPA1A-down F3-down|IL1R2-down F3-down|PDGFRA-down F3-down|FGF14-up TGFB3-up|PDGFRA-down FIGF-down|FLNC-up VCAM1-up|GADD45B-down JUN-down|GADD45B-down MMP2-up|GADD45B-down SERPINE1-down|GADD45B-down VCAM1-up|HSPA1A-down JUN-down|HSPA1B-down JUN-down|MAP3K8-down SERPINE1-down|NTRK2-up MMP2-up|PDGFRA-down MMP2-up|PDGFRA-down TGFB3-up|PDGFRA-down VCAM1-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 TGFB3-up_7043|BDNF-down_627 CCND1-up_595|BDNF-down_627 FIGF-down_2277|BDNF-down_627 JUN-down_3725|BDNF-down_627 MMP2-up_4313|BDNF-down_627 SERPINE1-down_5054|BDNF-down_627 TGFB3-up_7043|BDNF-down_627 VCAM1-up_7412|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|HSPA1A-down_3303 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|PDGFRA-down_5156 COL1A2-up_1278|HSPA1A-down_3303 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|DUSP1-down_1843 F3-down_2152|DUSP1-down_1843 JUN-down_3725|DUSP1-down_1843 MMP2-up_4313|DUSP1-down_1843 SERPINE1-down_5054|DUSP1-down_1843 VCAM1-up_7412|FLNC-up_2318 F3-down_2152|HSPA1A-down_3303 F3-down_2152|IL1R2-down_7850 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FGF14-up_2259 TGFB3-up_7043|PDGFRA-down_5156 FIGF-down_2277|FLNC-up_2318 VCAM1-up_7412|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 SERPINE1-down_5054|GADD45B-down_4616 VCAM1-up_7412|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|MAP3K8-down_1326 SERPINE1-down_5054|NTRK2-up_4915 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 VCAM1-up_7412
hsa04010	hsa04970	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	0.023	ARRB1-down ADRB1-down|BDNF-down ADRB1-down|MAP3K8-down ADRB1-down|HSPA1A-down AQP5-up|HSPA1B-down AQP5-up|JUN-down AQP5-up|ARRB1-down KCNMA1-up|BDNF-down KCNMA1-up|BDNF-down KCNN4-up|DUSP1-down MUC5B-up|FLNC-up MUC5B-up|JUN-down GUCY1A3-up|PDGFRA-down GUCY1A3-up|HSPA1A-down MUC5B-up|JUN-down KCNMA1-up|JUN-down KCNN4-up|JUN-down MUC5B-up	ARRB1-down_408 ADRB1-down_153|BDNF-down_627 ADRB1-down_153|MAP3K8-down_1326 ADRB1-down_153|HSPA1A-down_3303 AQP5-up_362|HSPA1B-down_3304 AQP5-up_362|JUN-down_3725 AQP5-up_362|ARRB1-down_408 KCNMA1-up_3778|BDNF-down_627 KCNMA1-up_3778|BDNF-down_627 KCNN4-up_3783|DUSP1-down_1843 MUC5B-up_727897|FLNC-up_2318 MUC5B-up_727897|JUN-down_3725 GUCY1A3-up_2982|PDGFRA-down_5156 GUCY1A3-up_2982|HSPA1A-down_3303 MUC5B-up_727897|JUN-down_3725 KCNMA1-up_3778|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MUC5B-up_727897
hsa04010	hsa04974	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0.001	BDNF-down COL18A1-up|BDNF-down KCNN4-up|BDNF-down MME-down|BDNF-down PRSS1-up|BDNF-down SLC1A1-down|TGFB3-up COL10A1-up|FGF14-up COL14A1-up|JUN-down COL14A1-up|TGFB3-up COL14A1-up|JUN-down COL18A1-up|TGFB3-up COL18A1-up|HSPA1A-down COL1A1-up|JUN-down COL1A1-up|PDGFRA-down COL1A1-up|TGFB3-up COL1A1-up|JUN-down COL1A2-up|PDGFRA-down COL1A2-up|TGFB3-up COL1A2-up|HSPA1A-down COL3A1-up|JUN-down COL3A1-up|PDGFRA-down COL3A1-up|TGFB3-up COL3A1-up|JUN-down COL5A1-up|PDGFRA-down COL5A1-up|TGFB3-up COL5A1-up|JUN-down COL5A2-up|TGFB3-up COL5A2-up|JUN-down COL6A1-up|PDGFRA-down COL6A1-up|TGFB3-up COL6A1-up|JUN-down COL6A3-up|PDGFRA-down COL6A3-up|TGFB3-up COL6A3-up|JUN-down COL7A1-up|DUSP1-down MME-down|HSPA1A-down MME-down|HSPA1B-down MME-down|JUN-down KCNN4-up|JUN-down MME-down|JUN-down PRSS1-up|PDGFRA-down MME-down|NTRK2-up SLC1A1-down	BDNF-down_627 COL18A1-up_80781|BDNF-down_627 KCNN4-up_3783|BDNF-down_627 MME-down_4311|BDNF-down_627 PRSS1-up_5644|BDNF-down_627 SLC1A1-down_6505|TGFB3-up_7043 COL10A1-up_1300|FGF14-up_2259 COL14A1-up_7373|JUN-down_3725 COL14A1-up_7373|TGFB3-up_7043 COL14A1-up_7373|JUN-down_3725 COL18A1-up_80781|TGFB3-up_7043 COL18A1-up_80781|HSPA1A-down_3303 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|HSPA1A-down_3303 COL3A1-up_1281|JUN-down_3725 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|TGFB3-up_7043 COL3A1-up_1281|JUN-down_3725 COL5A1-up_1289|PDGFRA-down_5156 COL5A1-up_1289|TGFB3-up_7043 COL5A1-up_1289|JUN-down_3725 COL5A2-up_1290|TGFB3-up_7043 COL5A2-up_1290|JUN-down_3725 COL6A1-up_1291|PDGFRA-down_5156 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|JUN-down_3725 COL6A3-up_1293|PDGFRA-down_5156 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|JUN-down_3725 COL7A1-up_1294|DUSP1-down_1843 MME-down_4311|HSPA1A-down_3303 MME-down_4311|HSPA1B-down_3304 MME-down_4311|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MME-down_4311|JUN-down_3725 PRSS1-up_5644|PDGFRA-down_5156 MME-down_4311|NTRK2-up_4915 SLC1A1-down_6505
hsa04010	hsa05166	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	ARRB1-down CCND1-up|ARRB1-down FZD5-down|ARRB1-down JAK1-down|ARRB1-down JUN-down|ARRB1-down PDGFRA-down|ARRB1-down TGFB3-up|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down JAK1-down|BDNF-down JUN-down|BDNF-down PDGFRA-down|BDNF-down TGFB3-up|BDNF-down VCAM1-up|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|DUSP1-down JAK1-down|DUSP1-down JUN-down|DUSP1-down MYB-up|DUSP1-down PDGFRA-down|DUSP1-down VCAM1-up|FGF14-up FZD5-down|FGF14-up TGFB3-up|FLNC-up MYB-up|FLNC-up VCAM1-up|MAP3K8-down FZD5-down|NTRK2-up FZD5-down|GADD45B-down IL1R2-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down MYB-up|GADD45B-down VCAM1-up|HSPA1A-down JAK1-down|HSPA1A-down JUN-down|HSPA1A-down PDGFRA-down|HSPA1B-down JAK1-down|HSPA1B-down JUN-down|HSPA1B-down PDGFRA-down|MAP3K8-down MYB-up|MAP3K8-down PDGFRA-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 TGFB3-up_7043|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 JAK1-down_3716|BDNF-down_627 JUN-down_3725|BDNF-down_627 PDGFRA-down_5156|BDNF-down_627 TGFB3-up_7043|BDNF-down_627 VCAM1-up_7412|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|DUSP1-down_1843 JAK1-down_3716|DUSP1-down_1843 JUN-down_3725|DUSP1-down_1843 MYB-up_4602|DUSP1-down_1843 PDGFRA-down_5156|DUSP1-down_1843 VCAM1-up_7412|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TGFB3-up_7043|FLNC-up_2318 MYB-up_4602|FLNC-up_2318 VCAM1-up_7412|MAP3K8-down_1326 FZD5-down_7855|NTRK2-up_4915 FZD5-down_7855|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MYB-up_4602|GADD45B-down_4616 VCAM1-up_7412|HSPA1A-down_3303 JAK1-down_3716|HSPA1A-down_3303 JUN-down_3725|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 JAK1-down_3716|HSPA1B-down_3304 JUN-down_3725|HSPA1B-down_3304 PDGFRA-down_5156|MAP3K8-down_1326 MYB-up_4602|MAP3K8-down_1326 PDGFRA-down_5156
hsa04010	hsa05202	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	ARRB1-down FLT1-down|ARRB1-down IGF1-up|BDNF-down CCND2-up|BDNF-down FLT1-down|BDNF-down IGF1-up|BDNF-down PLAU-up|BDNF-down PROM1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|DUSP1-down FLT1-down|DUSP1-down IGF1-up|DUSP1-down NFKBIZ-down|DUSP1-down ZBTB16-down|FGF14-up FLT1-down|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JUN-down FLT1-down|PDGFRA-down FLT1-down|TGFB3-up FLT1-down|GADD45B-down IL1R2-down|GADD45B-down NFKBIZ-down|GADD45B-down PLAU-up|HSPA1A-down IGF1-up|HSPA1B-down ZBTB16-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|MAP3K8-down NFKBIZ-down|MAP3K8-down PLAU-up|MAP3K8-down ZBTB16-down|NTRK2-up PROM1-up|PDGFRA-down PLAU-up|PDGFRA-down PROM1-up|PDGFRA-down ZBTB16-down|TGFB3-up PLAU-up|TGFB3-up SIX1-up	ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 IGF1-up_3479|BDNF-down_627 CCND2-up_894|BDNF-down_627 FLT1-down_2321|BDNF-down_627 IGF1-up_3479|BDNF-down_627 PLAU-up_5328|BDNF-down_627 PROM1-up_8842|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|DUSP1-down_1843 FLT1-down_2321|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 NFKBIZ-down_64332|DUSP1-down_1843 ZBTB16-down_7704|FGF14-up_2259 FLT1-down_2321|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|PDGFRA-down_5156 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 NFKBIZ-down_64332|GADD45B-down_4616 PLAU-up_5328|HSPA1A-down_3303 IGF1-up_3479|HSPA1B-down_3304 ZBTB16-down_7704|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|MAP3K8-down_1326 NFKBIZ-down_64332|MAP3K8-down_1326 PLAU-up_5328|MAP3K8-down_1326 ZBTB16-down_7704|NTRK2-up_4915 PROM1-up_8842|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 PROM1-up_8842|PDGFRA-down_5156 ZBTB16-down_7704|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SIX1-up_6495
hsa04010	hsa05205	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	PDGFRA-down ANK2-up|ARRB1-down CCND1-up|ARRB1-down FLNC-up|ARRB1-down FZD5-down|ARRB1-down IGF1-up|BDNF-down CCND1-up|BDNF-down HBEGF-down|BDNF-down IGF1-up|BDNF-down MMP2-up|BDNF-down PLAU-up|BDNF-down THBS1-down|JUN-down CAV2-down|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|DUSP1-down HBEGF-down|DUSP1-down IGF1-up|DUSP1-down MMP2-up|DUSP1-down THBS1-down|FGF14-up FZD5-down|FLNC-up JUN-down|JUN-down FZD5-down|MAP3K8-down FZD5-down|NTRK2-up FZD5-down|PDGFRA-down FZD5-down|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down PLAU-up|GADD45B-down THBS1-down|IL1R2-down HBEGF-down|JUN-down HBEGF-down|MAP3K8-down HBEGF-down|NTRK2-up HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|HSPA1A-down IGF1-up|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|MAP3K8-down PLAU-up|NTRK2-up MMP2-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down PLAU-up|PDGFRA-down THBS1-down|TGFB3-up PLAU-up|TGFB3-up THBS1-down	PDGFRA-down_5156 ANK2-up_287|ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FLNC-up_2318|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 IGF1-up_3479|BDNF-down_627 CCND1-up_595|BDNF-down_627 HBEGF-down_1839|BDNF-down_627 IGF1-up_3479|BDNF-down_627 MMP2-up_4313|BDNF-down_627 PLAU-up_5328|BDNF-down_627 THBS1-down_7057|JUN-down_3725 CAV2-down_858|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|DUSP1-down_1843 HBEGF-down_1839|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 MMP2-up_4313|DUSP1-down_1843 THBS1-down_7057|FGF14-up_2259 FZD5-down_7855|FLNC-up_2318 JUN-down_3725|JUN-down_3725 FZD5-down_7855|MAP3K8-down_1326 FZD5-down_7855|NTRK2-up_4915 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|IL1R2-down_7850 HBEGF-down_1839|JUN-down_3725 HBEGF-down_1839|MAP3K8-down_1326 HBEGF-down_1839|NTRK2-up_4915 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|HSPA1A-down_3303 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|MAP3K8-down_1326 PLAU-up_5328|NTRK2-up_4915 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057
hsa04010	hsa05206	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	ARRB1-down CCND1-up|ARRB1-down PDGFRA-down|BDNF-down CCND1-up|BDNF-down CCND2-up|BDNF-down HMOX1-down|BDNF-down IRS2-down|BDNF-down MCL1-down|BDNF-down PDGFRA-down|BDNF-down PLAU-up|BDNF-down THBS1-down|BDNF-down TNC-up|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|TGFB3-up CCND1-up|DUSP1-down CCND2-up|GADD45B-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|NTRK2-up CCND2-up|TGFB3-up CCND2-up|JUN-down CYP24A1-up|DUSP1-down HMOX1-down|DUSP1-down IRS2-down|DUSP1-down MCL1-down|DUSP1-down PDGFRA-down|DUSP1-down THBS1-down|FLNC-up MMP16-up|FLNC-up TNC-up|FLNC-up TP63-up|GADD45B-down HMOX1-down|GADD45B-down MCL1-down|GADD45B-down PLAU-up|GADD45B-down THBS1-down|HSPA1A-down HMOX1-down|HSPA1B-down HMOX1-down|JUN-down HMOX1-down|NTRK2-up HMOX1-down|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|JUN-down IRS2-down|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|MAP3K8-down MCL1-down|MAP3K8-down PDGFRA-down|MAP3K8-down PLAU-up|NTRK2-up TNC-up|NTRK2-up TP63-up|TGFB3-up PLAU-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 PDGFRA-down_5156|BDNF-down_627 CCND1-up_595|BDNF-down_627 CCND2-up_894|BDNF-down_627 HMOX1-down_3162|BDNF-down_627 IRS2-down_8660|BDNF-down_627 MCL1-down_4170|BDNF-down_627 PDGFRA-down_5156|BDNF-down_627 PLAU-up_5328|BDNF-down_627 THBS1-down_7057|BDNF-down_627 TNC-up_3371|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|DUSP1-down_1843 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|NTRK2-up_4915 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|JUN-down_3725 CYP24A1-up_1591|DUSP1-down_1843 HMOX1-down_3162|DUSP1-down_1843 IRS2-down_8660|DUSP1-down_1843 MCL1-down_4170|DUSP1-down_1843 PDGFRA-down_5156|DUSP1-down_1843 THBS1-down_7057|FLNC-up_2318 MMP16-up_4325|FLNC-up_2318 TNC-up_3371|FLNC-up_2318 TP63-up_8626|GADD45B-down_4616 HMOX1-down_3162|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|HSPA1A-down_3303 HMOX1-down_3162|HSPA1B-down_3304 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|NTRK2-up_4915 HMOX1-down_3162|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|JUN-down_3725 IRS2-down_8660|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|MAP3K8-down_1326 MCL1-down_4170|MAP3K8-down_1326 PDGFRA-down_5156|MAP3K8-down_1326 PLAU-up_5328|NTRK2-up_4915 TNC-up_3371|NTRK2-up_4915 TP63-up_8626|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa04010	hsa05219	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.002	ARRB1-down CCND1-up|BDNF-down CCND1-up|BDNF-down HBEGF-down|BDNF-down MMP1-up|BDNF-down MMP2-up|BDNF-down THBS1-down|DUSP1-down CCND1-up|GADD45B-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MAP3K8-down CCND1-up|NTRK2-up CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|GADD45B-down DAPK2-down|MAP3K8-down DAPK2-down|DUSP1-down HBEGF-down|DUSP1-down MMP1-up|DUSP1-down MMP2-up|DUSP1-down THBS1-down|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down THBS1-down|IL1R2-down HBEGF-down|JUN-down HBEGF-down|MAP3K8-down HBEGF-down|NTRK2-up HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|PDGFRA-down MMP1-up|TGFB3-up MMP1-up|NTRK2-up MMP2-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down THBS1-down|TGFB3-up THBS1-down	ARRB1-down_408 CCND1-up_595|BDNF-down_627 CCND1-up_595|BDNF-down_627 HBEGF-down_1839|BDNF-down_627 MMP1-up_4312|BDNF-down_627 MMP2-up_4313|BDNF-down_627 THBS1-down_7057|DUSP1-down_1843 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|NTRK2-up_4915 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|GADD45B-down_4616 DAPK2-down_23604|MAP3K8-down_1326 DAPK2-down_23604|DUSP1-down_1843 HBEGF-down_1839|DUSP1-down_1843 MMP1-up_4312|DUSP1-down_1843 MMP2-up_4313|DUSP1-down_1843 THBS1-down_7057|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 THBS1-down_7057|IL1R2-down_7850 HBEGF-down_1839|JUN-down_3725 HBEGF-down_1839|MAP3K8-down_1326 HBEGF-down_1839|NTRK2-up_4915 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|PDGFRA-down_5156 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|NTRK2-up_4915 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057
hsa04010	hsa05410	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.028	ARRB1-down IGF1-up|ARRB1-down TGFB3-up|BDNF-down IGF1-up|BDNF-down TGFB3-up|FLNC-up DES-up|DUSP1-down IGF1-up|DUSP1-down PRKAA2-up|DUSP1-down TNNC1-down|FGF14-up TGFB3-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TTN-down|HSPA1A-down IGF1-up|HSPA1A-down TNNC1-down|HSPA1B-down TNNC1-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|PDGFRA-down IGF1-up|JUN-down ITGB4-up|PDGFRA-down ITGB4-up|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|MAP3K8-down PRKAA2-up|MAP3K8-down TNNC1-down|PDGFRA-down TGFB3-up	ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 TGFB3-up_7043|BDNF-down_627 IGF1-up_3479|BDNF-down_627 TGFB3-up_7043|FLNC-up_2318 DES-up_1674|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 PRKAA2-up_5563|DUSP1-down_1843 TNNC1-down_7134|FGF14-up_2259 TGFB3-up_7043|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TTN-down_7273|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 TNNC1-down_7134|HSPA1B-down_3304 TNNC1-down_7134|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MAP3K8-down_1326 PRKAA2-up_5563|MAP3K8-down_1326 TNNC1-down_7134|PDGFRA-down_5156 TGFB3-up_7043
hsa04010	hsa05412	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.02	BDNF-down CDH2-up|BDNF-down TCF7L2-up|JUN-down CDH2-up|MAP3K8-down CDH2-up|NTRK2-up CDH2-up|PDGFRA-down CDH2-up|TGFB3-up CDH2-up|FLNC-up DES-up|TGFB3-up DES-up|FGF14-up TCF7L2-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|JUN-down ITGB4-up|PDGFRA-down ITGB4-up|TGFB3-up ITGB8-up|JUN-down TCF7L2-up|PDGFRA-down TCF7L2-up|TGFB3-up TCF7L2-up	BDNF-down_627 CDH2-up_1000|BDNF-down_627 TCF7L2-up_6934|JUN-down_3725 CDH2-up_1000|MAP3K8-down_1326 CDH2-up_1000|NTRK2-up_4915 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|FLNC-up_2318 DES-up_1674|TGFB3-up_7043 DES-up_1674|FGF14-up_2259 TCF7L2-up_6934|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|JUN-down_3725 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 TCF7L2-up_6934|PDGFRA-down_5156 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934
hsa04010	hsa05414	MAPK signaling pathway - Homo sapiens (human)	ARRB1,BDNF,DUSP1,GADD45B,HSPA1A,HSPA1B,IL1R2,JUN,MAP3K8,PDGFRA,FGF14,FLNC,NTRK2,TGFB3	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.031	ARRB1-down ADRB1-down|BDNF-down ADRB1-down|MAP3K8-down ADRB1-down|ARRB1-down IGF1-up|ARRB1-down TGFB3-up|BDNF-down IGF1-up|BDNF-down TGFB3-up|FLNC-up DES-up|DUSP1-down IGF1-up|DUSP1-down TNNC1-down|FGF14-up TGFB3-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TTN-down|HSPA1A-down IGF1-up|HSPA1A-down TNNC1-down|HSPA1B-down TNNC1-down|JUN-down IGF1-up|MAP3K8-down IGF1-up|NTRK2-up IGF1-up|PDGFRA-down IGF1-up|JUN-down ITGB4-up|PDGFRA-down ITGB4-up|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down|MAP3K8-down TNNC1-down|PDGFRA-down TGFB3-up	ARRB1-down_408 ADRB1-down_153|BDNF-down_627 ADRB1-down_153|MAP3K8-down_1326 ADRB1-down_153|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 TGFB3-up_7043|BDNF-down_627 IGF1-up_3479|BDNF-down_627 TGFB3-up_7043|FLNC-up_2318 DES-up_1674|DUSP1-down_1843 IGF1-up_3479|DUSP1-down_1843 TNNC1-down_7134|FGF14-up_2259 TGFB3-up_7043|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TTN-down_7273|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 TNNC1-down_7134|HSPA1B-down_3304 TNNC1-down_7134|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|NTRK2-up_4915 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MAP3K8-down_1326 TNNC1-down_7134|PDGFRA-down_5156 TGFB3-up_7043
hsa04014	hsa04062	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	0.032	FLT1-down ARRB1-down|IGF1-up ARRB1-down|PDGFRA-down ARRB1-down|FLT1-down CCL11-up|IGF1-up CCL11-up|FIGF-down CXCL12-up|FLT1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|IGF1-up CXCL14-up|IGF1-up CXCL2-down|FLT1-down CXCR2-down|IGF1-up CXCR2-down	FLT1-down_2321 ARRB1-down_408|IGF1-up_3479 ARRB1-down_408|PDGFRA-down_5156 ARRB1-down_408|FLT1-down_2321 CCL11-up_6356|IGF1-up_3479 CCL11-up_6356|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|IGF1-up_3479 CXCL14-up_9547|IGF1-up_3479 CXCL2-down_2920|FLT1-down_2321 CXCR2-down_3579|IGF1-up_3479 CXCR2-down_3579
hsa04014	hsa04064	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	0.004	FIGF-down CXCL12-up|FLT1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|IGF1-up CXCL2-down|FIGF-down PLAU-up|FIGF-down VCAM1-up|FLT1-down PLAU-up|FLT1-down VCAM1-up|IGF1-up VCAM1-up|PDGFRA-down PLAU-up|PDGFRA-down VCAM1-up	FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|IGF1-up_3479 CXCL2-down_2920|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 VCAM1-up_7412
hsa04014	hsa04310	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	FIGF-down CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|PDGFRA-down CCND2-up|FGF14-up FZD5-down|FGF14-up SFRP4-up|FGF14-up TCF7L2-up|FIGF-down JUN-down|FIGF-down MMP7-up|FIGF-down SERPINF1-up|FLT1-down FZD5-down|FLT1-down JUN-down|FLT1-down MMP7-up|FLT1-down SERPINF1-up|FLT1-down SFRP2-up|PDGFRA-down FZD5-down|IGF1-up JUN-down|IGF1-up MMP7-up|IGF1-up SERPINF1-up|IGF1-up SFRP2-up|IGF1-up SFRP4-up|IGF1-up TCF7L2-up|PDGFRA-down JUN-down|PDGFRA-down SFRP2-up|PDGFRA-down SFRP4-up|PDGFRA-down TCF7L2-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 SFRP4-up_6424|FGF14-up_2259 TCF7L2-up_6934|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP7-up_4316|FIGF-down_2277 SERPINF1-up_5176|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP7-up_4316|FLT1-down_2321 SERPINF1-up_5176|FLT1-down_2321 SFRP2-up_6423|PDGFRA-down_5156 FZD5-down_7855|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP7-up_4316|IGF1-up_3479 SERPINF1-up_5176|IGF1-up_3479 SFRP2-up_6423|IGF1-up_3479 SFRP4-up_6424|IGF1-up_3479 TCF7L2-up_6934|PDGFRA-down_5156 JUN-down_3725|PDGFRA-down_5156 SFRP2-up_6423|PDGFRA-down_5156 SFRP4-up_6424|PDGFRA-down_5156 TCF7L2-up_6934
hsa04014	hsa04350	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0	FGF14-up TGFB3-up|FIGF-down TGFB3-up|FIGF-down THBS1-down|FLT1-down ID1-down|FLT1-down SMAD6-down|FLT1-down TGFB3-up|FLT1-down THBS1-down|IGF1-up ID1-down|PDGFRA-down ID1-down|IGF1-up SMAD6-down|IGF1-up TGFB3-up|IGF1-up THBS1-down|PDGFRA-down LTBP1-up|PDGFRA-down TGFB3-up|PDGFRA-down THBS1-down	FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SMAD6-down_4091|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|IGF1-up_3479 SMAD6-down_4091|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 THBS1-down_7057|PDGFRA-down_5156 LTBP1-up_4052|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 THBS1-down_7057
hsa04014	hsa04360	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0.002	FLT1-down BOC-up|FIGF-down CXCL12-up|FLT1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|IGF1-up EPHA3-up|PDGFRA-down EPHA3-up|FLT1-down NTN1-up|FLT1-down RND1-down|FLT1-down ROBO2-up|FLT1-down SEMA3E-down|IGF1-up NTN1-up|PDGFRA-down NTN1-up|PDGFRA-down RND1-down|PDGFRA-down ROBO2-up	FLT1-down_2321 BOC-up_91653|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|IGF1-up_3479 EPHA3-up_2042|PDGFRA-down_5156 EPHA3-up_2042|FLT1-down_2321 NTN1-up_9423|FLT1-down_2321 RND1-down_27289|FLT1-down_2321 ROBO2-up_6092|FLT1-down_2321 SEMA3E-down_9723|IGF1-up_3479 NTN1-up_9423|PDGFRA-down_5156 NTN1-up_9423|PDGFRA-down_5156 RND1-down_27289|PDGFRA-down_5156 ROBO2-up_6092
hsa04014	hsa04380	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0.013	IGF1-up CTSK-up|IGF1-up FHL2-up|FIGF-down JUN-down|FLT1-down FOSL2-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up FOSL2-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down JUN-down|PDGFRA-down SOCS3-down	IGF1-up_3479 CTSK-up_1513|IGF1-up_3479 FHL2-up_2274|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 FOSL2-down_2355|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 FOSL2-down_2355|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 JUN-down_3725|PDGFRA-down_5156 SOCS3-down_9021
hsa04014	hsa04390	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0	FIGF-down CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|PDGFRA-down CCND2-up|FGF14-up FZD5-down|FGF14-up TCF7L2-up|FGF14-up TGFB3-up|FIGF-down SERPINE1-down|FIGF-down TGFB3-up|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down SERPINE1-down|FLT1-down SOX2-up|FLT1-down TGFB3-up|PDGFRA-down FZD5-down|IGF1-up ID1-down|PDGFRA-down ID1-down|IGF1-up SERPINE1-down|IGF1-up SOX2-up|IGF1-up TCF7L2-up|IGF1-up TGFB3-up|PDGFRA-down SOX2-up|PDGFRA-down TCF7L2-up|PDGFRA-down TGFB3-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TCF7L2-up_6934|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 SERPINE1-down_5054|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 SOX2-up_6657|FLT1-down_2321 TGFB3-up_7043|PDGFRA-down_5156 FZD5-down_7855|IGF1-up_3479 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 SOX2-up_6657|IGF1-up_3479 TCF7L2-up_6934|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 SOX2-up_6657|PDGFRA-down_5156 TCF7L2-up_6934|PDGFRA-down_5156 TGFB3-up_7043
hsa04014	hsa04512	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	FIGF-down COL1A1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|PLA2G1B-down COL1A2-up|PDGFRA-down COL6A1-up|PDGFRA-down COL6A3-up|IGF1-up COMP-up|FIGF-down SPP1-up|FIGF-down THBS1-down|FIGF-down THBS2-up|FIGF-down TNC-up|FLT1-down ITGB4-up|FLT1-down SPP1-up|FLT1-down THBS1-down|FLT1-down THBS2-up|FLT1-down TNC-up|IGF1-up SPP1-up|IGF1-up THBS1-down|IGF1-up THBS2-up|IGF1-up TNC-up|PDGFRA-down ITGB4-up|PDGFRA-down SPP1-up|PDGFRA-down THBS1-down|PDGFRA-down TNC-up	FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|PDGFRA-down_5156 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|IGF1-up_3479 COMP-up_1311|FIGF-down_2277 SPP1-up_6696|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 THBS2-up_7058|FIGF-down_2277 TNC-up_3371|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 SPP1-up_6696|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 THBS2-up_7058|FLT1-down_2321 TNC-up_3371|IGF1-up_3479 SPP1-up_6696|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 THBS2-up_7058|IGF1-up_3479 TNC-up_3371|PDGFRA-down_5156 ITGB4-up_3691|PDGFRA-down_5156 SPP1-up_6696|PDGFRA-down_5156 THBS1-down_7057|PDGFRA-down_5156 TNC-up_3371
hsa04014	hsa04514	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	IGF1-up CD274-down|PDGFRA-down CD274-down|FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|PDGFRA-down CDH2-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|FGF14-up NFASC-up|FIGF-down VCAM1-up|FLT1-down NCAM1-up|FLT1-down SELL-down|FLT1-down VCAM1-up|IGF1-up NCAM1-up|IGF1-up SELL-down|IGF1-up VCAM1-up|PDGFRA-down NCAM1-up|PDGFRA-down VCAM1-up	IGF1-up_3479 CD274-down_29126|PDGFRA-down_5156 CD274-down_29126|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|FGF14-up_2259 NFASC-up_23114|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 NCAM1-up_4684|FLT1-down_2321 SELL-down_6402|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 NCAM1-up_4684|IGF1-up_3479 SELL-down_6402|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 NCAM1-up_4684|PDGFRA-down_5156 VCAM1-up_7412
hsa04014	hsa04610	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.001	FLT1-down CFH-up|IGF1-up CFH-up|PDGFRA-down CFH-up|FLT1-down F3-down|IGF1-up F3-down|PDGFRA-down F3-down|FIGF-down PLAU-up|FIGF-down SERPINE1-down|FLT1-down PLAU-up|FLT1-down SERPINE1-down|FLT1-down TFPI-down|IGF1-up SERPINE1-down|PDGFRA-down PLAU-up	FLT1-down_2321 CFH-up_3075|IGF1-up_3479 CFH-up_3075|PDGFRA-down_5156 CFH-up_3075|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 SERPINE1-down_5054|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TFPI-down_7035|IGF1-up_3479 SERPINE1-down_5054|PDGFRA-down_5156 PLAU-up_5328
hsa04014	hsa04630	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0.001	FIGF-down CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|PDGFRA-down CCND2-up|PLA2G1B-down CSF3R-down|FLT1-down JAK1-down|FLT1-down MCL1-down|FLT1-down SOCS3-down|IGF1-up JAK1-down|IGF1-up LIFR-down|IGF1-up MCL1-down|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down MCL1-down|PDGFRA-down SOCS3-down	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|PLA2G1B-down_5319 CSF3R-down_1441|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LIFR-down_3977|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 MCL1-down_4170|PDGFRA-down_5156 SOCS3-down_9021
hsa04014	hsa04668	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.008	IGF1-up CXCL2-down|FIGF-down JUN-down|FIGF-down VCAM1-up|FLT1-down JUN-down|FLT1-down SOCS3-down|FLT1-down VCAM1-up|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|PDGFRA-down JUN-down|PDGFRA-down MAP3K8-down|PDGFRA-down SOCS3-down|PDGFRA-down VCAM1-up	IGF1-up_3479 CXCL2-down_2920|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 JUN-down_3725|PDGFRA-down_5156 MAP3K8-down_1326|PDGFRA-down_5156 SOCS3-down_9021|PDGFRA-down_5156 VCAM1-up_7412
hsa04014	hsa04670	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0.001	FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|FIGF-down CXCL12-up|FLT1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|FIGF-down MMP2-up|FIGF-down VCAM1-up|FLT1-down MMP2-up|FLT1-down VCAM1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up|PDGFRA-down MMP2-up|PDGFRA-down VCAM1-up	FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|PDGFRA-down_5156 VCAM1-up_7412
hsa04014	hsa04915	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.016	FIGF-down HBEGF-down|FIGF-down JUN-down|FIGF-down MMP2-up|FLT1-down HBEGF-down|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JUN-down|FLT1-down MMP2-up|IGF1-up HBEGF-down|PDGFRA-down HBEGF-down|IGF1-up HSPA1A-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|IGF1-up JUN-down|IGF1-up MMP2-up|PDGFRA-down JUN-down|PDGFRA-down MMP2-up	FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP2-up_4313|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|IGF1-up_3479 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|IGF1-up_3479 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|PDGFRA-down_5156 JUN-down_3725|PDGFRA-down_5156 MMP2-up_4313
hsa04014	hsa04933	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.007	FLT1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|PLA2G1B-down COL1A2-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|PDGFRA-down COL3A1-up|FLT1-down F3-down|IGF1-up F3-down|PDGFRA-down F3-down|FGF14-up TGFB3-up|FLT1-down JUN-down|FLT1-down MMP2-up|FLT1-down SERPINE1-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|PDGFRA-down JUN-down|PDGFRA-down MMP2-up|PDGFRA-down TGFB3-up|PDGFRA-down VCAM1-up	FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FGF14-up_2259 TGFB3-up_7043|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 JUN-down_3725|PDGFRA-down_5156 MMP2-up_4313|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 VCAM1-up_7412
hsa04014	hsa04974	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	FGF14-up COL14A1-up|FIGF-down COL18A1-up|FLT1-down COL18A1-up|IGF1-up COL18A1-up|FIGF-down COL1A1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|PLA2G1B-down COL1A2-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|PDGFRA-down COL3A1-up|FLT1-down COL5A1-up|IGF1-up COL5A1-up|PDGFRA-down COL5A1-up|PLA2G1B-down COL5A2-up|PDGFRA-down COL6A1-up|PDGFRA-down COL6A3-up|PLA2G1B-down CPA3-up|FLT1-down MME-down|IGF1-up MME-down|IGF1-up PRSS1-up|IGF1-up SLC1A1-down|PDGFRA-down MME-down|PLA2G1B-down PRSS1-up	FGF14-up_2259 COL14A1-up_7373|FIGF-down_2277 COL18A1-up_80781|FLT1-down_2321 COL18A1-up_80781|IGF1-up_3479 COL18A1-up_80781|FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|FLT1-down_2321 COL5A1-up_1289|IGF1-up_3479 COL5A1-up_1289|PDGFRA-down_5156 COL5A1-up_1289|PLA2G1B-down_5319 COL5A2-up_1290|PDGFRA-down_5156 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|PLA2G1B-down_5319 CPA3-up_1359|FLT1-down_2321 MME-down_4311|IGF1-up_3479 MME-down_4311|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SLC1A1-down_6505|PDGFRA-down_5156 MME-down_4311|PLA2G1B-down_5319 PRSS1-up_5644
hsa04014	hsa05145	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.003	FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JAK1-down|FLT1-down LDLR-down|FLT1-down TGFB3-up|IGF1-up HSPA1A-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|IGF1-up JAK1-down|IGF1-up LDLR-down|IGF1-up TGFB3-up|PDGFRA-down JAK1-down|PLA2G1B-down LDLR-down|PDGFRA-down TGFB3-up	FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 LDLR-down_3949|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 JAK1-down_3716|PLA2G1B-down_5319 LDLR-down_3949|PDGFRA-down_5156 TGFB3-up_7043
hsa04014	hsa05146	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	FIGF-down COL1A1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|PLA2G1B-down COL1A2-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|PDGFRA-down COL3A1-up|FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down TGFB3-up|IGF1-up TGFB3-up|PDGFRA-down TGFB3-up	FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 TGFB3-up_7043
hsa04014	hsa05152	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.005	FIGF-down CD74-up|IGF1-up CD74-up|FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down JAK1-down|FLT1-down TGFB3-up|IGF1-up JAK1-down|IGF1-up TGFB3-up|PDGFRA-down JAK1-down|PDGFRA-down TGFB3-up	FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 TGFB3-up_7043
hsa04014	hsa05164	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0.012	FIGF-down JUN-down|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up HSPA1A-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PRSS1-up|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down JUN-down|PDGFRA-down SOCS3-down|PLA2G1B-down PRSS1-up	FIGF-down_2277 JUN-down_3725|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 JUN-down_3725|PDGFRA-down_5156 SOCS3-down_9021|PLA2G1B-down_5319 PRSS1-up_5644
hsa04014	hsa05166	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.002	FIGF-down CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|FGF14-up FZD5-down|FGF14-up TGFB3-up|FIGF-down JUN-down|FIGF-down PDGFRA-down|FIGF-down TGFB3-up|FIGF-down VCAM1-up|FLT1-down FZD5-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MYB-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up MYB-up|IGF1-up TGFB3-up|IGF1-up VCAM1-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MYB-up_4602|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MYB-up_4602|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412
hsa04014	hsa05168	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.02	FIGF-down CD74-up|IGF1-up CD74-up|FIGF-down JUN-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down JUN-down|PDGFRA-down SOCS3-down	FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 JUN-down_3725|PDGFRA-down_5156 SOCS3-down_9021
hsa04014	hsa05206	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.002	FIGF-down CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|IGF1-up CYP24A1-up|FIGF-down HMOX1-down|FIGF-down PDGFRA-down|FIGF-down PLAU-up|FIGF-down THBS1-down|FIGF-down TNC-up|FLT1-down HMOX1-down|FLT1-down IRS2-down|FLT1-down MCL1-down|FLT1-down MMP16-up|FLT1-down PDGFRA-down|FLT1-down PLAU-up|FLT1-down SERPINB5-up|FLT1-down THBS1-down|FLT1-down TNC-up|FLT1-down TP63-up|IGF1-up HMOX1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up THBS1-down|IGF1-up TNC-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|IGF1-up_3479 CYP24A1-up_1591|FIGF-down_2277 HMOX1-down_3162|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 TNC-up_3371|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 MMP16-up_4325|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 TNC-up_3371|FLT1-down_2321 TP63-up_8626|IGF1-up_3479 HMOX1-down_3162|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 TNC-up_3371
hsa04014	hsa05219	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.001	FIGF-down CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|FIGF-down HBEGF-down|FIGF-down MMP1-up|FIGF-down MMP2-up|FIGF-down THBS1-down|FLT1-down HBEGF-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down THBS1-down|IGF1-up HBEGF-down|PDGFRA-down HBEGF-down|IGF1-up MMP1-up|IGF1-up MMP2-up|IGF1-up THBS1-down|PDGFRA-down MMP1-up|PDGFRA-down MMP2-up|PDGFRA-down THBS1-down	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THBS1-down_7057|PDGFRA-down_5156 MMP1-up_4312|PDGFRA-down_5156 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057
hsa04014	hsa05412	Ras signaling pathway - Homo sapiens (human)	FIGF,FLT1,PDGFRA,PLA2G1B,FGF14,IGF1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.032	FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|PDGFRA-down CDH2-up|FGF14-up TCF7L2-up|FLT1-down ITGB4-up|IGF1-up TCF7L2-up|PDGFRA-down ITGB4-up|PDGFRA-down TCF7L2-up	FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|FGF14-up_2259 TCF7L2-up_6934|FLT1-down_2321 ITGB4-up_3691|IGF1-up_3479 TCF7L2-up_6934|PDGFRA-down_5156 ITGB4-up_3691|PDGFRA-down_5156 TCF7L2-up_6934
hsa04015	hsa04060	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	0.002	FPR1-down CCL11-up|IGF1-up CCL11-up|IGF1-up CD27-up|FPR1-down CXCL12-up|ID1-down CXCL12-up|IGF1-up CXCL12-up|THBS1-down CXCL12-up|FPR1-down CXCL13-up|IGF1-up CXCL14-up|THBS1-down CXCL14-up|FPR1-down CXCL2-down|IGF1-up CXCL2-down|FPR1-down CXCL3-down|FPR1-down CXCR2-down|IGF1-up CXCR2-down|THBS1-down CXCR2-down|FGF14-up TGFB3-up|ID1-down PDGFRA-down|ID1-down TGFB3-up|ID1-down TNFRSF19-up|IGF1-up IL18R1-down|IGF1-up IL18RAP-down|IGF1-up LIFR-down|IGF1-up TGFB3-up|IGF1-up TNFRSF19-up|THBS1-down TGFB3-up	FPR1-down_2357 CCL11-up_6356|IGF1-up_3479 CCL11-up_6356|IGF1-up_3479 CD27-up_939|FPR1-down_2357 CXCL12-up_6387|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|FPR1-down_2357 CXCL13-up_10563|IGF1-up_3479 CXCL14-up_9547|THBS1-down_7057 CXCL14-up_9547|FPR1-down_2357 CXCL2-down_2920|IGF1-up_3479 CXCL2-down_2920|FPR1-down_2357 CXCL3-down_2921|FPR1-down_2357 CXCR2-down_3579|IGF1-up_3479 CXCR2-down_3579|THBS1-down_7057 CXCR2-down_3579|FGF14-up_2259 TGFB3-up_7043|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 TGFB3-up_7043|ID1-down_3397 TNFRSF19-up_55504|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 IL18RAP-down_8807|IGF1-up_3479 LIFR-down_3977|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 TNFRSF19-up_55504|THBS1-down_7057 TGFB3-up_7043
hsa04015	hsa04062	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	0	FLT1-down ARRB1-down|FPR1-down ARRB1-down|IGF1-up ARRB1-down|PDGFRA-down ARRB1-down|FLT1-down CCL11-up|FPR1-down CCL11-up|IGF1-up CCL11-up|FIGF-down CXCL12-up|FLT1-down CXCL12-up|FPR1-down CXCL12-up|ID1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|THBS1-down CXCL12-up|FPR1-down CXCL13-up|IGF1-up CXCL14-up|THBS1-down CXCL14-up|FPR1-down CXCL2-down|IGF1-up CXCL2-down|FPR1-down CXCL3-down|FLT1-down CXCR2-down|FPR1-down CXCR2-down|IGF1-up CXCR2-down|THBS1-down CXCR2-down	FLT1-down_2321 ARRB1-down_408|FPR1-down_2357 ARRB1-down_408|IGF1-up_3479 ARRB1-down_408|PDGFRA-down_5156 ARRB1-down_408|FLT1-down_2321 CCL11-up_6356|FPR1-down_2357 CCL11-up_6356|IGF1-up_3479 CCL11-up_6356|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|FPR1-down_2357 CXCL13-up_10563|IGF1-up_3479 CXCL14-up_9547|THBS1-down_7057 CXCL14-up_9547|FPR1-down_2357 CXCL2-down_2920|IGF1-up_3479 CXCL2-down_2920|FPR1-down_2357 CXCL3-down_2921|FLT1-down_2321 CXCR2-down_3579|FPR1-down_2357 CXCR2-down_3579|IGF1-up_3479 CXCR2-down_3579|THBS1-down_7057 CXCR2-down_3579
hsa04015	hsa04064	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	0	FIGF-down CXCL12-up|FLT1-down CXCL12-up|FPR1-down CXCL12-up|ID1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|THBS1-down CXCL12-up|FPR1-down CXCL2-down|IGF1-up CXCL2-down|FIGF-down PLAU-up|FIGF-down VCAM1-up|FLT1-down PLAU-up|FLT1-down VCAM1-up|THBS1-down GADD45B-down|ID1-down PLAU-up|IGF1-up VCAM1-up|PDGFRA-down PLAU-up|PDGFRA-down VCAM1-up|THBS1-down PLAU-up|THBS1-down VCAM1-up	FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|FPR1-down_2357 CXCL2-down_2920|IGF1-up_3479 CXCL2-down_2920|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 VCAM1-up_7412|THBS1-down_7057 GADD45B-down_4616|ID1-down_3397 PLAU-up_5328|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 VCAM1-up_7412|THBS1-down_7057 PLAU-up_5328|THBS1-down_7057 VCAM1-up_7412
hsa04015	hsa04310	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	FIGF-down CCND1-up|FLT1-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|THBS1-down CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|PDGFRA-down CCND2-up|THBS1-down CCND2-up|FGF14-up FZD5-down|FGF14-up SFRP4-up|FGF14-up TCF7L2-up|FIGF-down JUN-down|FIGF-down MMP7-up|FIGF-down SERPINF1-up|FLT1-down FZD5-down|FLT1-down JUN-down|FLT1-down MMP7-up|FLT1-down SERPINF1-up|FLT1-down SFRP2-up|PDGFRA-down FZD5-down|ID1-down JUN-down|ID1-down SERPINF1-up|IGF1-up JUN-down|IGF1-up MMP7-up|IGF1-up SERPINF1-up|IGF1-up SFRP2-up|IGF1-up SFRP4-up|IGF1-up TCF7L2-up|PDGFRA-down JUN-down|THBS1-down JUN-down|THBS1-down MMP7-up|PDGFRA-down SFRP2-up|PDGFRA-down SFRP4-up|PDGFRA-down TCF7L2-up|THBS1-down SERPINF1-up|THBS1-down SFRP2-up|THBS1-down SFRP4-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|THBS1-down_7057 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|THBS1-down_7057 CCND2-up_894|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 SFRP4-up_6424|FGF14-up_2259 TCF7L2-up_6934|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP7-up_4316|FIGF-down_2277 SERPINF1-up_5176|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP7-up_4316|FLT1-down_2321 SERPINF1-up_5176|FLT1-down_2321 SFRP2-up_6423|PDGFRA-down_5156 FZD5-down_7855|ID1-down_3397 JUN-down_3725|ID1-down_3397 SERPINF1-up_5176|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP7-up_4316|IGF1-up_3479 SERPINF1-up_5176|IGF1-up_3479 SFRP2-up_6423|IGF1-up_3479 SFRP4-up_6424|IGF1-up_3479 TCF7L2-up_6934|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS1-down_7057 MMP7-up_4316|PDGFRA-down_5156 SFRP2-up_6423|PDGFRA-down_5156 SFRP4-up_6424|PDGFRA-down_5156 TCF7L2-up_6934|THBS1-down_7057 SERPINF1-up_5176|THBS1-down_7057 SFRP2-up_6423|THBS1-down_7057 SFRP4-up_6424
hsa04015	hsa04350	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0.022	FGF14-up TGFB3-up|FIGF-down TGFB3-up|FIGF-down THBS1-down|FLT1-down ID1-down|FLT1-down SMAD6-down|FLT1-down TGFB3-up|FLT1-down THBS1-down|IGF1-up SMAD6-down|IGF1-up TGFB3-up|PDGFRA-down LTBP1-up|PDGFRA-down TGFB3-up|PDGFRA-down THBS1-down	FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SMAD6-down_4091|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 SMAD6-down_4091|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 LTBP1-up_4052|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 THBS1-down_7057
hsa04015	hsa04360	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0	FLT1-down BOC-up|FPR1-down BOC-up|FIGF-down CXCL12-up|FLT1-down CXCL12-up|FPR1-down CXCL12-up|ID1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|THBS1-down CXCL12-up|IGF1-up EPHA3-up|PDGFRA-down EPHA3-up|FLT1-down NTN1-up|FLT1-down RND1-down|FLT1-down ROBO2-up|FLT1-down SEMA3E-down|IGF1-up NTN1-up|PDGFRA-down NTN1-up|THBS1-down NTN1-up|PDGFRA-down RND1-down|PDGFRA-down ROBO2-up|THBS1-down SEMA3E-down	FLT1-down_2321 BOC-up_91653|FPR1-down_2357 BOC-up_91653|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|IGF1-up_3479 EPHA3-up_2042|PDGFRA-down_5156 EPHA3-up_2042|FLT1-down_2321 NTN1-up_9423|FLT1-down_2321 RND1-down_27289|FLT1-down_2321 ROBO2-up_6092|FLT1-down_2321 SEMA3E-down_9723|IGF1-up_3479 NTN1-up_9423|PDGFRA-down_5156 NTN1-up_9423|THBS1-down_7057 NTN1-up_9423|PDGFRA-down_5156 RND1-down_27289|PDGFRA-down_5156 ROBO2-up_6092|THBS1-down_7057 SEMA3E-down_9723
hsa04015	hsa04380	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0.013	IGF1-up CTSK-up|THBS1-down CTSK-up|IGF1-up FHL2-up|FIGF-down JUN-down|FLT1-down FOSL2-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up FOSL2-down|ID1-down JUN-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down JUN-down|THBS1-down JUN-down|PDGFRA-down SOCS3-down|THBS1-down SOCS3-down	IGF1-up_3479 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|IGF1-up_3479 FHL2-up_2274|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 FOSL2-down_2355|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 FOSL2-down_2355|ID1-down_3397 JUN-down_3725|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|PDGFRA-down_5156 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021
hsa04015	hsa04390	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0	FIGF-down CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|THBS1-down CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|PDGFRA-down CCND2-up|THBS1-down CCND2-up|FGF14-up FZD5-down|FGF14-up TCF7L2-up|FGF14-up TGFB3-up|FIGF-down SERPINE1-down|FIGF-down TGFB3-up|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down SERPINE1-down|FLT1-down SOX2-up|FLT1-down TGFB3-up|PDGFRA-down FZD5-down|IGF1-up SERPINE1-down|IGF1-up SOX2-up|IGF1-up TCF7L2-up|IGF1-up TGFB3-up|P2RY1-down SOX2-up|PDGFRA-down SOX2-up|PDGFRA-down TCF7L2-up|PDGFRA-down TGFB3-up|THBS1-down SERPINE1-down|THBS1-down SOX2-up|THBS1-down TGFB3-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|THBS1-down_7057 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|THBS1-down_7057 CCND2-up_894|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TCF7L2-up_6934|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 SERPINE1-down_5054|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 SOX2-up_6657|FLT1-down_2321 TGFB3-up_7043|PDGFRA-down_5156 FZD5-down_7855|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 SOX2-up_6657|IGF1-up_3479 TCF7L2-up_6934|IGF1-up_3479 TGFB3-up_7043|P2RY1-down_5028 SOX2-up_6657|PDGFRA-down_5156 SOX2-up_6657|PDGFRA-down_5156 TCF7L2-up_6934|PDGFRA-down_5156 TGFB3-up_7043|THBS1-down_7057 SERPINE1-down_5054|THBS1-down_7057 SOX2-up_6657|THBS1-down_7057 TGFB3-up_7043
hsa04015	hsa04512	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	FIGF-down COL1A1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|PDGFRA-down COL6A1-up|PDGFRA-down COL6A3-up|IGF1-up COMP-up|FIGF-down SPP1-up|FIGF-down THBS1-down|FIGF-down THBS2-up|FIGF-down TNC-up|FLT1-down ITGB4-up|FLT1-down SPP1-up|FLT1-down THBS1-down|FLT1-down THBS2-up|FLT1-down TNC-up|ID1-down SPP1-up|ID1-down THBS1-down|ID1-down THBS2-up|IGF1-up SPP1-up|IGF1-up THBS2-up|IGF1-up TNC-up|PDGFRA-down ITGB4-up|P2RY1-down SPP1-up|PDGFRA-down SPP1-up|PDGFRA-down THBS1-down|PDGFRA-down TNC-up	FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|PDGFRA-down_5156 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|IGF1-up_3479 COMP-up_1311|FIGF-down_2277 SPP1-up_6696|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 THBS2-up_7058|FIGF-down_2277 TNC-up_3371|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 SPP1-up_6696|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 THBS2-up_7058|FLT1-down_2321 TNC-up_3371|ID1-down_3397 SPP1-up_6696|ID1-down_3397 THBS1-down_7057|ID1-down_3397 THBS2-up_7058|IGF1-up_3479 SPP1-up_6696|IGF1-up_3479 THBS2-up_7058|IGF1-up_3479 TNC-up_3371|PDGFRA-down_5156 ITGB4-up_3691|P2RY1-down_5028 SPP1-up_6696|PDGFRA-down_5156 SPP1-up_6696|PDGFRA-down_5156 THBS1-down_7057|PDGFRA-down_5156 TNC-up_3371
hsa04015	hsa04514	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	IGF1-up CD274-down|PDGFRA-down CD274-down|FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|PDGFRA-down CDH2-up|THBS1-down CDH2-up|THBS1-down CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|THBS1-down CLDN5-down|FGF14-up NFASC-up|FIGF-down VCAM1-up|FLT1-down NCAM1-up|FLT1-down SELL-down|FLT1-down VCAM1-up|IGF1-up NCAM1-up|IGF1-up SELL-down|IGF1-up VCAM1-up|THBS1-down ITGB8-up|PDGFRA-down NCAM1-up|THBS1-down NCAM1-up|PDGFRA-down VCAM1-up|THBS1-down VCAM1-up	IGF1-up_3479 CD274-down_29126|PDGFRA-down_5156 CD274-down_29126|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS1-down_7057 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|FGF14-up_2259 NFASC-up_23114|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 NCAM1-up_4684|FLT1-down_2321 SELL-down_6402|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 NCAM1-up_4684|IGF1-up_3479 SELL-down_6402|IGF1-up_3479 VCAM1-up_7412|THBS1-down_7057 ITGB8-up_3696|PDGFRA-down_5156 NCAM1-up_4684|THBS1-down_7057 NCAM1-up_4684|PDGFRA-down_5156 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412
hsa04015	hsa04610	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0	FLT1-down CFH-up|IGF1-up CFH-up|PDGFRA-down CFH-up|THBS1-down CFH-up|FLT1-down F3-down|IGF1-up F3-down|P2RY1-down F3-down|PDGFRA-down F3-down|THBS1-down F3-down|FIGF-down PLAU-up|FIGF-down SERPINE1-down|FLT1-down PLAU-up|FLT1-down SERPINE1-down|FLT1-down TFPI-down|FPR1-down SERPIND1-up|ID1-down PLAU-up|ID1-down SERPINE1-down|IGF1-up SERPINE1-down|PDGFRA-down PLAU-up|THBS1-down PLAU-up|THBS1-down SERPINE1-down|THBS1-down TFPI-down	FLT1-down_2321 CFH-up_3075|IGF1-up_3479 CFH-up_3075|PDGFRA-down_5156 CFH-up_3075|THBS1-down_7057 CFH-up_3075|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|P2RY1-down_5028 F3-down_2152|PDGFRA-down_5156 F3-down_2152|THBS1-down_7057 F3-down_2152|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 SERPINE1-down_5054|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TFPI-down_7035|FPR1-down_2357 SERPIND1-up_3053|ID1-down_3397 PLAU-up_5328|ID1-down_3397 SERPINE1-down_5054|IGF1-up_3479 SERPINE1-down_5054|PDGFRA-down_5156 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS1-down_7057 SERPINE1-down_5054|THBS1-down_7057 TFPI-down_7035
hsa04015	hsa04630	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0.002	FIGF-down CCND1-up|FLT1-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|THBS1-down CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|PDGFRA-down CCND2-up|THBS1-down CCND2-up|FLT1-down JAK1-down|FLT1-down MCL1-down|FLT1-down SOCS3-down|FPR1-down MCL1-down|IGF1-up JAK1-down|IGF1-up LIFR-down|IGF1-up MCL1-down|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down MCL1-down|THBS1-down MCL1-down|PDGFRA-down SOCS3-down|THBS1-down SOCS3-down	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|THBS1-down_7057 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|THBS1-down_7057 CCND2-up_894|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 SOCS3-down_9021|FPR1-down_2357 MCL1-down_4170|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LIFR-down_3977|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 MCL1-down_4170|THBS1-down_7057 MCL1-down_4170|PDGFRA-down_5156 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021
hsa04015	hsa04668	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	FPR1-down CXCL2-down|IGF1-up CXCL2-down|FPR1-down CXCL3-down|FIGF-down JUN-down|FIGF-down VCAM1-up|FLT1-down JUN-down|FLT1-down SOCS3-down|FLT1-down VCAM1-up|ID1-down JUN-down|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|PDGFRA-down JUN-down|THBS1-down JUN-down|PDGFRA-down MAP3K8-down|PDGFRA-down SOCS3-down|PDGFRA-down VCAM1-up|THBS1-down SOCS3-down|THBS1-down VCAM1-up	FPR1-down_2357 CXCL2-down_2920|IGF1-up_3479 CXCL2-down_2920|FPR1-down_2357 CXCL3-down_2921|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|FLT1-down_2321 VCAM1-up_7412|ID1-down_3397 JUN-down_3725|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|PDGFRA-down_5156 MAP3K8-down_1326|PDGFRA-down_5156 SOCS3-down_9021|PDGFRA-down_5156 VCAM1-up_7412|THBS1-down_7057 SOCS3-down_9021|THBS1-down_7057 VCAM1-up_7412
hsa04015	hsa04670	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	THBS1-down CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|THBS1-down CLDN5-down|FIGF-down CXCL12-up|FLT1-down CXCL12-up|FPR1-down CXCL12-up|ID1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|THBS1-down CXCL12-up|FIGF-down MMP2-up|FIGF-down VCAM1-up|FLT1-down MMP2-up|FLT1-down VCAM1-up|ID1-down MMP2-up|ID1-down THY1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up|PDGFRA-down MMP2-up|THBS1-down MMP2-up|PDGFRA-down VCAM1-up|THBS1-down THY1-up|THBS1-down VCAM1-up	THBS1-down_7057 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 VCAM1-up_7412|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THY1-up_7070|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|PDGFRA-down_5156 VCAM1-up_7412|THBS1-down_7057 THY1-up_7070|THBS1-down_7057 VCAM1-up_7412
hsa04015	hsa04915	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.008	FIGF-down HBEGF-down|FIGF-down JUN-down|FIGF-down MMP2-up|FLT1-down HBEGF-down|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JUN-down|FLT1-down MMP2-up|IGF1-up HBEGF-down|PDGFRA-down HBEGF-down|THBS1-down HBEGF-down|IGF1-up HSPA1A-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|ID1-down JUN-down|ID1-down MMP2-up|IGF1-up JUN-down|IGF1-up MMP2-up|PDGFRA-down JUN-down|THBS1-down JUN-down|PDGFRA-down MMP2-up|THBS1-down MMP2-up	FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP2-up_4313|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|IGF1-up_3479 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|THBS1-down_7057 HBEGF-down_1839|IGF1-up_3479 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|PDGFRA-down_5156 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313
hsa04015	hsa04933	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	FLT1-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|THBS1-down CCND1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|THBS1-down COL1A1-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|THBS1-down COL1A2-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|PDGFRA-down COL3A1-up|THBS1-down COL3A1-up|FLT1-down F3-down|IGF1-up F3-down|P2RY1-down F3-down|PDGFRA-down F3-down|THBS1-down F3-down|FGF14-up TGFB3-up|FLT1-down JUN-down|FLT1-down MMP2-up|FLT1-down SERPINE1-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|ID1-down JUN-down|ID1-down MMP2-up|ID1-down SERPINE1-down|ID1-down TGFB3-up|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|PDGFRA-down JUN-down|THBS1-down JUN-down|PDGFRA-down MMP2-up|THBS1-down MMP2-up|PDGFRA-down TGFB3-up|PDGFRA-down VCAM1-up|THBS1-down SERPINE1-down|THBS1-down TGFB3-up|THBS1-down VCAM1-up	FLT1-down_2321 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|THBS1-down_7057 CCND1-up_595|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|P2RY1-down_5028 F3-down_2152|PDGFRA-down_5156 F3-down_2152|THBS1-down_7057 F3-down_2152|FGF14-up_2259 TGFB3-up_7043|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|ID1-down_3397 SERPINE1-down_5054|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|PDGFRA-down_5156 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 VCAM1-up_7412|THBS1-down_7057 SERPINE1-down_5054|THBS1-down_7057 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412
hsa04015	hsa04974	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	THBS1-down COL10A1-up|FGF14-up COL14A1-up|THBS1-down COL14A1-up|THBS1-down COL15A1-up|THBS1-down COL17A1-up|FIGF-down COL18A1-up|FLT1-down COL18A1-up|IGF1-up COL18A1-up|THBS1-down COL18A1-up|FIGF-down COL1A1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|THBS1-down COL1A1-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|THBS1-down COL1A2-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|PDGFRA-down COL3A1-up|THBS1-down COL3A1-up|FLT1-down COL5A1-up|IGF1-up COL5A1-up|PDGFRA-down COL5A1-up|THBS1-down COL5A1-up|THBS1-down COL5A2-up|PDGFRA-down COL6A1-up|THBS1-down COL6A1-up|PDGFRA-down COL6A3-up|THBS1-down COL6A3-up|THBS1-down COL7A1-up|FLT1-down MME-down|FPR1-down MME-down|IGF1-up MME-down|IGF1-up PRSS1-up|IGF1-up SLC1A1-down|P2RY1-down KCNN4-up|PDGFRA-down MME-down|THBS1-down MME-down	THBS1-down_7057 COL10A1-up_1300|FGF14-up_2259 COL14A1-up_7373|THBS1-down_7057 COL14A1-up_7373|THBS1-down_7057 COL15A1-up_1306|THBS1-down_7057 COL17A1-up_1308|FIGF-down_2277 COL18A1-up_80781|FLT1-down_2321 COL18A1-up_80781|IGF1-up_3479 COL18A1-up_80781|THBS1-down_7057 COL18A1-up_80781|FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|FLT1-down_2321 COL5A1-up_1289|IGF1-up_3479 COL5A1-up_1289|PDGFRA-down_5156 COL5A1-up_1289|THBS1-down_7057 COL5A1-up_1289|THBS1-down_7057 COL5A2-up_1290|PDGFRA-down_5156 COL6A1-up_1291|THBS1-down_7057 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|THBS1-down_7057 COL6A3-up_1293|THBS1-down_7057 COL7A1-up_1294|FLT1-down_2321 MME-down_4311|FPR1-down_2357 MME-down_4311|IGF1-up_3479 MME-down_4311|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SLC1A1-down_6505|P2RY1-down_5028 KCNN4-up_3783|PDGFRA-down_5156 MME-down_4311|THBS1-down_7057 MME-down_4311
hsa04015	hsa05145	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.004	FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JAK1-down|FLT1-down LDLR-down|FLT1-down TGFB3-up|IGF1-up HSPA1A-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|ID1-down TGFB3-up|IGF1-up JAK1-down|IGF1-up LDLR-down|IGF1-up TGFB3-up|PDGFRA-down JAK1-down|THBS1-down LAMA3-down|THBS1-down LDLR-down|PDGFRA-down TGFB3-up|THBS1-down TGFB3-up	FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 LDLR-down_3949|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 JAK1-down_3716|THBS1-down_7057 LAMA3-down_3909|THBS1-down_7057 LDLR-down_3949|PDGFRA-down_5156 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04015	hsa05146	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	FIGF-down COL1A1-up|FLT1-down COL1A1-up|IGF1-up COL1A1-up|PDGFRA-down COL1A1-up|THBS1-down COL1A1-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|IGF1-up COL1A2-up|PDGFRA-down COL1A2-up|THBS1-down COL1A2-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|PDGFRA-down COL3A1-up|THBS1-down COL3A1-up|FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down TGFB3-up|ID1-down TGFB3-up|IGF1-up TGFB3-up|THBS1-down LAMA3-down|PDGFRA-down TGFB3-up|THBS1-down TGFB3-up	FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|IGF1-up_3479 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 TGFB3-up_7043|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 TGFB3-up_7043|THBS1-down_7057 LAMA3-down_3909|PDGFRA-down_5156 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04015	hsa05152	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.002	FIGF-down CD74-up|IGF1-up CD74-up|THBS1-down CD74-up|FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down JAK1-down|FLT1-down TGFB3-up|ID1-down TGFB3-up|IGF1-up JAK1-down|IGF1-up TGFB3-up|PDGFRA-down JAK1-down|PDGFRA-down TGFB3-up|THBS1-down TGFB3-up	FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|THBS1-down_7057 CD74-up_972|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 TGFB3-up_7043|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04015	hsa05164	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0.042	FIGF-down JUN-down|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up HSPA1A-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|ID1-down JUN-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PRSS1-up|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down JUN-down|THBS1-down JUN-down|PDGFRA-down SOCS3-down|THBS1-down SOCS3-down|THBS1-down TMPRSS4-up	FIGF-down_2277 JUN-down_3725|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|ID1-down_3397 JUN-down_3725|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|PDGFRA-down_5156 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|THBS1-down_7057 TMPRSS4-up_56649
hsa04015	hsa05166	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	FIGF-down CCND1-up|FLT1-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|THBS1-down CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|THBS1-down CCND2-up|FGF14-up FZD5-down|FGF14-up TGFB3-up|FIGF-down JUN-down|FIGF-down PDGFRA-down|FIGF-down TGFB3-up|FIGF-down VCAM1-up|FLT1-down FZD5-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MYB-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|ID1-down JUN-down|ID1-down MYB-up|ID1-down PDGFRA-down|ID1-down TGFB3-up|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up MYB-up|IGF1-up TGFB3-up|IGF1-up VCAM1-up|THBS1-down JUN-down|THBS1-down MYB-up|THBS1-down TGFB3-up|THBS1-down VCAM1-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|THBS1-down_7057 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|THBS1-down_7057 CCND2-up_894|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MYB-up_4602|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|ID1-down_3397 JUN-down_3725|ID1-down_3397 MYB-up_4602|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MYB-up_4602|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|THBS1-down_7057 JUN-down_3725|THBS1-down_7057 MYB-up_4602|THBS1-down_7057 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412
hsa04015	hsa05168	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.013	FIGF-down CD74-up|IGF1-up CD74-up|THBS1-down CD74-up|FIGF-down JUN-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|ID1-down JUN-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down JUN-down|THBS1-down JUN-down|PDGFRA-down SOCS3-down|THBS1-down SOCS3-down	FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|THBS1-down_7057 CD74-up_972|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|ID1-down_3397 JUN-down_3725|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|PDGFRA-down_5156 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021
hsa04015	hsa05206	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.006	FIGF-down CCND1-up|FLT1-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|FLT1-down CCND2-up|IGF1-up CCND2-up|IGF1-up CYP24A1-up|FIGF-down HMOX1-down|FIGF-down PDGFRA-down|FIGF-down PLAU-up|FIGF-down THBS1-down|FIGF-down TNC-up|FLT1-down HMOX1-down|FLT1-down IRS2-down|FLT1-down MCL1-down|FLT1-down MMP16-up|FLT1-down PDGFRA-down|FLT1-down PLAU-up|FLT1-down SERPINB5-up|FLT1-down THBS1-down|FLT1-down TNC-up|FLT1-down TP63-up|FPR1-down MCL1-down|IGF1-up HMOX1-down|ID1-down PDGFRA-down|ID1-down PLAU-up|ID1-down THBS1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up TNC-up	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|FLT1-down_2321 CCND2-up_894|IGF1-up_3479 CCND2-up_894|IGF1-up_3479 CYP24A1-up_1591|FIGF-down_2277 HMOX1-down_3162|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 TNC-up_3371|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 MMP16-up_4325|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 TNC-up_3371|FLT1-down_2321 TP63-up_8626|FPR1-down_2357 MCL1-down_4170|IGF1-up_3479 HMOX1-down_3162|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 PLAU-up_5328|ID1-down_3397 THBS1-down_7057|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 TNC-up_3371
hsa04015	hsa05219	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.008	FIGF-down CCND1-up|FLT1-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|PDGFRA-down CCND1-up|FIGF-down HBEGF-down|FIGF-down MMP1-up|FIGF-down MMP2-up|FIGF-down THBS1-down|FLT1-down HBEGF-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down THBS1-down|IGF1-up HBEGF-down|PDGFRA-down HBEGF-down|ID1-down MMP1-up|ID1-down MMP2-up|ID1-down THBS1-down|IGF1-up MMP1-up|IGF1-up MMP2-up|PDGFRA-down MMP1-up|PDGFRA-down MMP2-up|PDGFRA-down THBS1-down	FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|ID1-down_3397 MMP1-up_4312|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THBS1-down_7057|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|PDGFRA-down_5156 MMP1-up_4312|PDGFRA-down_5156 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057
hsa04015	hsa05323	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.002	IGF1-up CTSK-up|THBS1-down CTSK-up|FIGF-down CXCL12-up|FPR1-down CXCL12-up|ID1-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|THBS1-down CXCL12-up|FGF14-up TGFB3-up|FIGF-down FLT1-down|FIGF-down JUN-down|FIGF-down MMP1-up|FIGF-down TGFB3-up|ID1-down JUN-down|ID1-down MMP1-up|ID1-down TGFB3-up|IGF1-up JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|PDGFRA-down JUN-down|THBS1-down JUN-down|PDGFRA-down MMP1-up|THBS1-down MMP1-up|PDGFRA-down TGFB3-up|THBS1-down TGFB3-up	IGF1-up_3479 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|FIGF-down_2277 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 TGFB3-up_7043|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP1-up_4312|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|PDGFRA-down_5156 JUN-down_3725|THBS1-down_7057 JUN-down_3725|PDGFRA-down_5156 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|PDGFRA-down_5156 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04015	hsa05412	Rap1 signaling pathway - Homo sapiens (human)	FIGF,FLT1,FPR1,ID1,P2RY1,PDGFRA,THBS1,FGF14,IGF1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.016	FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|PDGFRA-down CDH2-up|THBS1-down CDH2-up|FGF14-up TCF7L2-up|FLT1-down ITGB4-up|IGF1-up TCF7L2-up|PDGFRA-down ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|PDGFRA-down TCF7L2-up	FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|FGF14-up_2259 TCF7L2-up_6934|FLT1-down_2321 ITGB4-up_3691|IGF1-up_3479 TCF7L2-up_6934|PDGFRA-down_5156 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|PDGFRA-down_5156 TCF7L2-up_6934
hsa04022	hsa04610	cGMP-PKG signaling pathway - Homo sapiens (human)	ADRB1,EDNRB,IRS2,NPR1,GUCY1A3,KCNMA1,PLN	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.03	ADRB1-down SERPINE1-down|ADRB1-down TFPI-down|EDNRB-down CFH-up|KCNMA1-up CFH-up|NPR1-down CFH-up|EDNRB-down SERPINE1-down|EDNRB-down TFPI-down|IRS2-down SERPINE1-down|NPR1-down SERPINE1-down	ADRB1-down_153 SERPINE1-down_5054|ADRB1-down_153 TFPI-down_7035|EDNRB-down_1910 CFH-up_3075|KCNMA1-up_3778 CFH-up_3075|NPR1-down_4881 CFH-up_3075|EDNRB-down_1910 SERPINE1-down_5054|EDNRB-down_1910 TFPI-down_7035|IRS2-down_8660 SERPINE1-down_5054|NPR1-down_4881 SERPINE1-down_5054
hsa04060	hsa04064	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	0	CCL11-up CXCL12-up|CCL11-up VCAM1-up|CCL13-up CXCL3-down|CCL13-up CXCR2-down|CD27-up CXCL12-up|CD27-up VCAM1-up|CSF3R-down CXCL12-up|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up LIFR-down|CXCL12-up PDGFRA-down|CXCL13-up VCAM1-up|CXCL14-up VCAM1-up|CXCL3-down PLAU-up|CXCR2-down GADD45B-down|CXCR2-down VCAM1-up|FIGF-down PLAU-up|FIGF-down VCAM1-up|FLT1-down PLAU-up|FLT1-down VCAM1-up|IL18R1-down GADD45B-down|IL18RAP-down GADD45B-down|IL1R2-down GADD45B-down|IL18R1-down VCAM1-up|IL18RAP-down VCAM1-up|LIFR-down VCAM1-up|PDGFRA-down PLAU-up|PDGFRA-down VCAM1-up|TGFB3-up PLAU-up|TGFB3-up VCAM1-up	CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 CXCL3-down_2921|CCL13-up_6357 CXCR2-down_3579|CD27-up_939 CXCL12-up_6387|CD27-up_939 VCAM1-up_7412|CSF3R-down_1441 CXCL12-up_6387|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 PDGFRA-down_5156|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 VCAM1-up_7412|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 GADD45B-down_4616|CXCR2-down_3579 VCAM1-up_7412|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 VCAM1-up_7412|IL18R1-down_8809 GADD45B-down_4616|IL18RAP-down_8807 GADD45B-down_4616|IL1R2-down_7850 GADD45B-down_4616|IL18R1-down_8809 VCAM1-up_7412|IL18RAP-down_8807 VCAM1-up_7412|LIFR-down_3977 VCAM1-up_7412|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 VCAM1-up_7412
hsa04060	hsa04068	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	0	CCL11-up IGF1-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|FLT1-down CCND2-up|PDGFRA-down CCND2-up|CD27-up FBXO32-up|CD27-up IGF1-up|CXCL12-up GADD45B-down|CXCL12-up IGF1-up|CXCL12-up S1PR1-down|CXCL12-up SOD2-down|CXCL12-up TGFB3-up|CXCL13-up S1PR1-down|CXCL14-up IGF1-up|CXCL2-down GADD45B-down|CXCL2-down IGF1-up|CXCL2-down IRS2-down|CXCL2-down S1PR1-down|CXCL2-down SOD2-down|CXCL3-down S1PR1-down|CXCR2-down GADD45B-down|CXCR2-down IGF1-up|CXCR2-down S1PR1-down|FIGF-down IGF1-up|FIGF-down S1PR1-down|FIGF-down TGFB3-up|FLT1-down IGF1-up|FLT1-down IRS2-down|FLT1-down S1PR1-down|FLT1-down TGFB3-up|IL18R1-down GADD45B-down|IL18RAP-down GADD45B-down|IL1R2-down GADD45B-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down IRS2-down|PDGFRA-down S1PR1-down|PDGFRA-down TGFB3-up	CCL11-up_6356 IGF1-up_3479|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|FLT1-down_2321 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|CD27-up_939 FBXO32-up_114907|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 GADD45B-down_4616|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 S1PR1-down_1901|CXCL12-up_6387 SOD2-down_6648|CXCL12-up_6387 TGFB3-up_7043|CXCL13-up_10563 S1PR1-down_1901|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 GADD45B-down_4616|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 S1PR1-down_1901|CXCL2-down_2920 SOD2-down_6648|CXCL3-down_2921 S1PR1-down_1901|CXCR2-down_3579 GADD45B-down_4616|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 S1PR1-down_1901|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 S1PR1-down_1901|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 S1PR1-down_1901|FLT1-down_2321 TGFB3-up_7043|IL18R1-down_8809 GADD45B-down_4616|IL18RAP-down_8807 GADD45B-down_4616|IL1R2-down_7850 GADD45B-down_4616|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 IRS2-down_8660|PDGFRA-down_5156 S1PR1-down_1901|PDGFRA-down_5156 TGFB3-up_7043
hsa04060	hsa04080	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	0	FLT1-down ADRB1-down|CXCL12-up APLNR-up|CXCL13-up APLNR-up|CXCL2-down APLNR-up|CXCL3-down APLNR-up|CXCR2-down APLNR-up|FLT1-down APLNR-up|CCL11-up FPR1-down|CXCL12-up EDNRB-down|CXCL12-up FPR1-down|CXCL12-up FPR2-down|CXCL12-up GABBR2-up|CXCL12-up S1PR1-down|CXCL12-up VIPR1-down|CXCL13-up FPR1-down|CXCL13-up FPR2-down|CXCL13-up S1PR1-down|CXCL2-down FPR1-down|CXCL2-down FPR2-down|CXCL2-down S1PR1-down|CXCL3-down FPR1-down|CXCL3-down FPR2-down|CXCL3-down S1PR1-down|CXCR2-down FPR1-down|CXCR2-down FPR2-down|CXCR2-down GRIA1-down|CXCR2-down S1PR1-down|FLT1-down EDNRB-down|FIGF-down S1PR1-down|FLT1-down S1PR1-down|PDGFRA-down S1PR1-down	FLT1-down_2321 ADRB1-down_153|CXCL12-up_6387 APLNR-up_187|CXCL13-up_10563 APLNR-up_187|CXCL2-down_2920 APLNR-up_187|CXCL3-down_2921 APLNR-up_187|CXCR2-down_3579 APLNR-up_187|FLT1-down_2321 APLNR-up_187|CCL11-up_6356 FPR1-down_2357|CXCL12-up_6387 EDNRB-down_1910|CXCL12-up_6387 FPR1-down_2357|CXCL12-up_6387 FPR2-down_2358|CXCL12-up_6387 GABBR2-up_9568|CXCL12-up_6387 S1PR1-down_1901|CXCL12-up_6387 VIPR1-down_7433|CXCL13-up_10563 FPR1-down_2357|CXCL13-up_10563 FPR2-down_2358|CXCL13-up_10563 S1PR1-down_1901|CXCL2-down_2920 FPR1-down_2357|CXCL2-down_2920 FPR2-down_2358|CXCL2-down_2920 S1PR1-down_1901|CXCL3-down_2921 FPR1-down_2357|CXCL3-down_2921 FPR2-down_2358|CXCL3-down_2921 S1PR1-down_1901|CXCR2-down_3579 FPR1-down_2357|CXCR2-down_3579 FPR2-down_2358|CXCR2-down_3579 GRIA1-down_2890|CXCR2-down_3579 S1PR1-down_1901|FLT1-down_2321 EDNRB-down_1910|FIGF-down_2277 S1PR1-down_1901|FLT1-down_2321 S1PR1-down_1901|PDGFRA-down_5156 S1PR1-down_1901
hsa04060	hsa04115	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	0	CCL11-up IGF1-up|CCL11-up SERPINE1-down|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|FLT1-down CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|CD27-up IGF1-up|CXCL12-up GADD45B-down|CXCL12-up IGF1-up|CXCL12-up SERPINB5-up|CXCL12-up SERPINE1-down|CXCL12-up THBS1-down|CXCL14-up IGF1-up|CXCL14-up SERPINB5-up|CXCL14-up SERPINE1-down|CXCL14-up THBS1-down|CXCL2-down GADD45B-down|CXCL2-down IGF1-up|CXCR2-down GADD45B-down|CXCR2-down IGF1-up|CXCR2-down SERPINE1-down|CXCR2-down THBS1-down|FIGF-down IGF1-up|FIGF-down SERPINE1-down|FIGF-down THBS1-down|FLT1-down IGF1-up|FLT1-down SERPINB5-up|FLT1-down SERPINE1-down|FLT1-down THBS1-down|IL18R1-down GADD45B-down|IL18RAP-down GADD45B-down|IL1R2-down GADD45B-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down THBS1-down|TGFB3-up SERPINE1-down|TGFB3-up THBS1-down	CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 SERPINE1-down_5054|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|FLT1-down_2321 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 GADD45B-down_4616|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 THBS1-down_7057|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 SERPINB5-up_5268|CXCL14-up_9547 SERPINE1-down_5054|CXCL14-up_9547 THBS1-down_7057|CXCL2-down_2920 GADD45B-down_4616|CXCL2-down_2920 IGF1-up_3479|CXCR2-down_3579 GADD45B-down_4616|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 SERPINE1-down_5054|CXCR2-down_3579 THBS1-down_7057|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 SERPINE1-down_5054|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 THBS1-down_7057|IL18R1-down_8809 GADD45B-down_4616|IL18RAP-down_8807 GADD45B-down_4616|IL1R2-down_7850 GADD45B-down_4616|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 SERPINE1-down_5054|TGFB3-up_7043 THBS1-down_7057
hsa04060	hsa04151	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0	CCL11-up COL1A2-up|CCL11-up IGF1-up|CCL11-up JAK1-down|CCL11-up SPP1-up|CCL13-up SPP1-up|CD27-up CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|LIFR-down CCND1-up|TGFB3-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|TGFB3-up CCND2-up|CD27-up IGF1-up|CD27-up JAK1-down|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|TGFB3-up COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|TGFB3-up COL1A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|CXCL12-up COMP-up|TGFB3-up COMP-up|CXCL12-up IGF1-up|CXCL12-up JAK1-down|CXCL12-up MCL1-down|CXCL12-up MYB-up|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL13-up MCL1-down|CXCL13-up SPP1-up|CXCL14-up IGF1-up|CXCL14-up SPP1-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down IGF1-up|CXCL2-down MYB-up|CXCL2-down SPP1-up|CXCR2-down FLT1-down|CXCR2-down IGF1-up|CXCR2-down MCL1-down|CXCR2-down SPP1-up|CXCR2-down THBS1-down|TGFB3-up FGF14-up|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|IL1R2-down SPP1-up|TGFB3-up ITGB8-up|LIFR-down JAK1-down|LIFR-down SPP1-up|TNFRSF21-up MCL1-down|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 SPP1-up_6696|CCL13-up_6357 SPP1-up_6696|CD27-up_939 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|LIFR-down_3977 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD27-up_939 IGF1-up_3479|CD27-up_939 JAK1-down_3716|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|CXCL12-up_6387 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 MCL1-down_4170|CXCL13-up_10563 SPP1-up_6696|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 SPP1-up_6696|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 MYB-up_4602|CXCL2-down_2920 SPP1-up_6696|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 MCL1-down_4170|CXCR2-down_3579 SPP1-up_6696|CXCR2-down_3579 THBS1-down_7057|TGFB3-up_7043 FGF14-up_2259|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|IL1R2-down_7850 SPP1-up_6696|TGFB3-up_7043 ITGB8-up_3696|LIFR-down_3977 JAK1-down_3716|LIFR-down_3977 SPP1-up_6696|TNFRSF21-up_27242 MCL1-down_4170|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04060	hsa04152	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	0.003	CCL11-up IGF1-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CD27-up IGF1-up|CXCL12-up HMGCR-down|CXCL12-up IGF1-up|CXCL14-up IGF1-up|CXCL2-down IGF1-up|CXCL2-down IRS2-down|CXCL2-down SCD-down|CXCR2-down HMGCR-down|CXCR2-down IGF1-up|FLT1-down FASN-down|FIGF-down IGF1-up|FLT1-down HMGCR-down|FLT1-down IGF1-up|FLT1-down IRS2-down|TNFRSF21-up HMGCR-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down IRS2-down	CCL11-up_6356 IGF1-up_3479|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 HMGCR-down_3156|CXCL12-up_6387 IGF1-up_3479|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 SCD-down_6319|CXCR2-down_3579 HMGCR-down_3156|CXCR2-down_3579 IGF1-up_3479|FLT1-down_2321 FASN-down_2194|FIGF-down_2277 IGF1-up_3479|FLT1-down_2321 HMGCR-down_3156|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 IRS2-down_8660|TNFRSF21-up_27242 HMGCR-down_3156|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 IRS2-down_8660
hsa04060	hsa04213	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	0.011	CCL11-up IGF1-up|CD27-up IGF1-up|CXCL12-up IGF1-up|CXCL12-up SOD2-down|CXCL14-up IGF1-up|CXCL2-down HSPA1A-down|CXCL2-down IGF1-up|CXCL2-down IRS2-down|CXCL2-down SOD2-down|CXCR2-down IGF1-up|FIGF-down IGF1-up|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down IGF1-up|FLT1-down IRS2-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down IRS2-down	CCL11-up_6356 IGF1-up_3479|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 SOD2-down_6648|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 SOD2-down_6648|CXCR2-down_3579 IGF1-up_3479|FIGF-down_2277 IGF1-up_3479|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 IRS2-down_8660|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 IRS2-down_8660
hsa04060	hsa04310	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	CCL11-up JUN-down|CCL11-up MMP7-up|CCL13-up MMP7-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|FLT1-down CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|CD27-up JUN-down|CSF3R-down JUN-down|CXCL12-up JUN-down|CXCL12-up MMP7-up|CXCL12-up SERPINF1-up|CXCL12-up SFRP2-up|CXCL14-up JUN-down|CXCL14-up MMP7-up|CXCL2-down JUN-down|CXCL2-down MMP7-up|CXCL3-down JUN-down|CXCL3-down MMP7-up|CXCR2-down JUN-down|CXCR2-down MMP7-up|FIGF-down JUN-down|FIGF-down MMP7-up|FIGF-down SERPINF1-up|FLT1-down FZD5-down|FLT1-down JUN-down|FLT1-down MMP7-up|FLT1-down SERPINF1-up|FLT1-down SFRP2-up|PDGFRA-down FZD5-down|IL18R1-down JUN-down|IL18RAP-down JUN-down|LIFR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|TNFRSF21-up JUN-down|PDGFRA-down SFRP2-up|PDGFRA-down SFRP4-up|PDGFRA-down TCF7L2-up|TGFB3-up SFRP2-up|TGFB3-up SFRP4-up|TGFB3-up TCF7L2-up	CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP7-up_4316|CCL13-up_6357 MMP7-up_4316|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|FLT1-down_2321 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD27-up_939 JUN-down_3725|CSF3R-down_1441 JUN-down_3725|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP7-up_4316|CXCL12-up_6387 SERPINF1-up_5176|CXCL12-up_6387 SFRP2-up_6423|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP7-up_4316|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP7-up_4316|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP7-up_4316|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP7-up_4316|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP7-up_4316|FIGF-down_2277 SERPINF1-up_5176|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP7-up_4316|FLT1-down_2321 SERPINF1-up_5176|FLT1-down_2321 SFRP2-up_6423|PDGFRA-down_5156 FZD5-down_7855|IL18R1-down_8809 JUN-down_3725|IL18RAP-down_8807 JUN-down_3725|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|PDGFRA-down_5156 SFRP2-up_6423|PDGFRA-down_5156 SFRP4-up_6424|PDGFRA-down_5156 TCF7L2-up_6934|TGFB3-up_7043 SFRP2-up_6423|TGFB3-up_7043 SFRP4-up_6424|TGFB3-up_7043 TCF7L2-up_6934
hsa04060	hsa04350	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0.005	CXCL12-up ID1-down|CXCL12-up TGFB3-up|CXCL12-up THBS1-down|CXCL14-up THBS1-down|CXCR2-down THBS1-down|FIGF-down TGFB3-up|FIGF-down THBS1-down|FLT1-down ID1-down|FLT1-down SMAD6-down|FLT1-down TGFB3-up|FLT1-down THBS1-down|PDGFRA-down ID1-down|TNFRSF19-up ID1-down|PDGFRA-down LTBP1-up|PDGFRA-down TGFB3-up|PDGFRA-down THBS1-down	CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 THBS1-down_7057|CXCL14-up_9547 THBS1-down_7057|CXCR2-down_3579 THBS1-down_7057|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SMAD6-down_4091|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 THBS1-down_7057|PDGFRA-down_5156 ID1-down_3397|TNFRSF19-up_55504 ID1-down_3397|PDGFRA-down_5156 LTBP1-up_4052|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 THBS1-down_7057
hsa04060	hsa04360	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0.002	FLT1-down BOC-up|CCL11-up CXCL12-up|CCL13-up CXCL12-up|CD27-up CXCL12-up|CSF3R-down CXCL12-up|CXCL12-up CXCL2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up LIFR-down|CXCL12-up PDGFRA-down|PDGFRA-down EPHA3-up|FLT1-down NTN1-up|FLT1-down RND1-down|FLT1-down ROBO2-up|FLT1-down SEMA3E-down|PDGFRA-down NTN1-up|TGFB3-up NTN1-up|PDGFRA-down RND1-down|PDGFRA-down ROBO2-up	FLT1-down_2321 BOC-up_91653|CCL11-up_6356 CXCL12-up_6387|CCL13-up_6357 CXCL12-up_6387|CD27-up_939 CXCL12-up_6387|CSF3R-down_1441 CXCL12-up_6387|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 PDGFRA-down_5156|PDGFRA-down_5156 EPHA3-up_2042|FLT1-down_2321 NTN1-up_9423|FLT1-down_2321 RND1-down_27289|FLT1-down_2321 ROBO2-up_6092|FLT1-down_2321 SEMA3E-down_9723|PDGFRA-down_5156 NTN1-up_9423|TGFB3-up_7043 NTN1-up_9423|PDGFRA-down_5156 RND1-down_27289|PDGFRA-down_5156 ROBO2-up_6092
hsa04060	hsa04380	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0	CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up SOCS3-down|CD27-up CTSK-up|CD27-up JAK1-down|CD27-up JUN-down|CSF3R-down JAK1-down|CSF3R-down JUN-down|CSF3R-down SOCS3-down|CXCL12-up CTSK-up|CXCL14-up CTSK-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL13-up SOCS3-down|CXCL14-up JUN-down|CXCL2-down JUN-down|CXCL2-down SOCS3-down|CXCL3-down JUN-down|CXCL3-down SOCS3-down|CXCR2-down JUN-down|CXCR2-down SOCS3-down|IL18R1-down FHL2-up|IL18RAP-down FHL2-up|TNFRSF19-up FHL2-up|FIGF-down JUN-down|FLT1-down FOSL2-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|LIFR-down FOSL2-down|TGFB3-up FOSL2-down|IL18R1-down JUN-down|IL18R1-down SOCS3-down|IL18RAP-down JUN-down|IL18RAP-down SOCS3-down|IL1R2-down SOCS3-down|LIFR-down JAK1-down|PDGFRA-down JAK1-down|LIFR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|TNFRSF21-up JUN-down|LIFR-down SOCS3-down|PDGFRA-down SOCS3-down	CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SOCS3-down_9021|CD27-up_939 CTSK-up_1513|CD27-up_939 JAK1-down_3716|CD27-up_939 JUN-down_3725|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 JUN-down_3725|CSF3R-down_1441 SOCS3-down_9021|CXCL12-up_6387 CTSK-up_1513|CXCL14-up_9547 CTSK-up_1513|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL13-up_10563 SOCS3-down_9021|CXCL14-up_9547 JUN-down_3725|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 SOCS3-down_9021|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SOCS3-down_9021|IL18R1-down_8809 FHL2-up_2274|IL18RAP-down_8807 FHL2-up_2274|TNFRSF19-up_55504 FHL2-up_2274|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 FOSL2-down_2355|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|LIFR-down_3977 FOSL2-down_2355|TGFB3-up_7043 FOSL2-down_2355|IL18R1-down_8809 JUN-down_3725|IL18R1-down_8809 SOCS3-down_9021|IL18RAP-down_8807 JUN-down_3725|IL18RAP-down_8807 SOCS3-down_9021|IL1R2-down_7850 SOCS3-down_9021|LIFR-down_3977 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|LIFR-down_3977 SOCS3-down_9021|PDGFRA-down_5156 SOCS3-down_9021
hsa04060	hsa04390	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.001	CCL11-up SERPINE1-down|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|FLT1-down CCND2-up|PDGFRA-down CCND2-up|CXCL12-up ID1-down|CXCL12-up SERPINE1-down|CXCL12-up SOX2-up|CXCL12-up TGFB3-up|CXCL14-up SERPINE1-down|CXCR2-down SERPINE1-down|FIGF-down SERPINE1-down|FIGF-down TGFB3-up|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down SERPINE1-down|FLT1-down SOX2-up|FLT1-down TGFB3-up|PDGFRA-down FZD5-down|PDGFRA-down ID1-down|TNFRSF19-up ID1-down|LIFR-down SOX2-up|PDGFRA-down SOX2-up|PDGFRA-down TCF7L2-up|PDGFRA-down TGFB3-up	CCL11-up_6356 SERPINE1-down_5054|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|FLT1-down_2321 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 SOX2-up_6657|CXCL12-up_6387 TGFB3-up_7043|CXCL14-up_9547 SERPINE1-down_5054|CXCR2-down_3579 SERPINE1-down_5054|FIGF-down_2277 SERPINE1-down_5054|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 SOX2-up_6657|FLT1-down_2321 TGFB3-up_7043|PDGFRA-down_5156 FZD5-down_7855|PDGFRA-down_5156 ID1-down_3397|TNFRSF19-up_55504 ID1-down_3397|LIFR-down_3977 SOX2-up_6657|PDGFRA-down_5156 SOX2-up_6657|PDGFRA-down_5156 TCF7L2-up_6934|PDGFRA-down_5156 TGFB3-up_7043
hsa04060	hsa04510	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCL11-up COL1A2-up|CCL11-up IGF1-up|CCL11-up JUN-down|CCL11-up SPP1-up|CCL13-up SPP1-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|LIFR-down CCND1-up|TGFB3-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|TGFB3-up CCND2-up|CD27-up IGF1-up|CD27-up JUN-down|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|TGFB3-up COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|TGFB3-up COL1A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|CXCL12-up COMP-up|TGFB3-up COMP-up|CSF3R-down JUN-down|CXCL12-up IGF1-up|CXCL12-up JUN-down|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL13-up SPP1-up|CXCL14-up IGF1-up|CXCL14-up JUN-down|CXCL14-up SPP1-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down IGF1-up|CXCL2-down JUN-down|CXCL2-down SPP1-up|CXCL3-down JUN-down|CXCR2-down FLT1-down|CXCR2-down IGF1-up|CXCR2-down JUN-down|CXCR2-down SPP1-up|CXCR2-down THBS1-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|IL18R1-down JUN-down|IL18RAP-down JUN-down|IL1R2-down SPP1-up|TGFB3-up ITGB8-up|LIFR-down JUN-down|TGFB3-up JUN-down|TNFRSF21-up JUN-down|LIFR-down SPP1-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SPP1-up_6696|CCL13-up_6357 SPP1-up_6696|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|LIFR-down_3977 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD27-up_939 IGF1-up_3479|CD27-up_939 JUN-down_3725|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|CXCL12-up_6387 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|CSF3R-down_1441 JUN-down_3725|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 SPP1-up_6696|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 SPP1-up_6696|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SPP1-up_6696|CXCL3-down_2921 JUN-down_3725|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SPP1-up_6696|CXCR2-down_3579 THBS1-down_7057|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|IL18R1-down_8809 JUN-down_3725|IL18RAP-down_8807 JUN-down_3725|IL1R2-down_7850 SPP1-up_6696|TGFB3-up_7043 ITGB8-up_3696|LIFR-down_3977 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|LIFR-down_3977 SPP1-up_6696|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04060	hsa04512	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCL11-up COL1A2-up|CCL11-up SPP1-up|CCL13-up SPP1-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|FIGF-down COL1A1-up|FLT1-down COL1A1-up|PDGFRA-down COL1A1-up|TGFB3-up COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|PDGFRA-down COL1A2-up|TGFB3-up COL1A2-up|PDGFRA-down COL6A1-up|TGFB3-up COL6A1-up|PDGFRA-down COL6A3-up|TGFB3-up COL6A3-up|CXCL12-up COMP-up|TGFB3-up COMP-up|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL13-up SPP1-up|CXCL14-up SPP1-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down SPP1-up|CXCR2-down SPP1-up|CXCR2-down THBS1-down|FIGF-down SPP1-up|FIGF-down THBS1-down|FIGF-down THBS2-up|FIGF-down TNC-up|FLT1-down ITGB4-up|FLT1-down SPP1-up|FLT1-down THBS1-down|FLT1-down THBS2-up|FLT1-down TNC-up|IL1R2-down SPP1-up|PDGFRA-down ITGB4-up|TGFB3-up ITGB8-up|LIFR-down SPP1-up|PDGFRA-down SPP1-up|PDGFRA-down THBS1-down|PDGFRA-down TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 SPP1-up_6696|CCL13-up_6357 SPP1-up_6696|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|PDGFRA-down_5156 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|CXCL12-up_6387 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 SPP1-up_6696|CXCL14-up_9547 SPP1-up_6696|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 SPP1-up_6696|CXCR2-down_3579 SPP1-up_6696|CXCR2-down_3579 THBS1-down_7057|FIGF-down_2277 SPP1-up_6696|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 THBS2-up_7058|FIGF-down_2277 TNC-up_3371|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 SPP1-up_6696|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 THBS2-up_7058|FLT1-down_2321 TNC-up_3371|IL1R2-down_7850 SPP1-up_6696|PDGFRA-down_5156 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|LIFR-down_3977 SPP1-up_6696|PDGFRA-down_5156 SPP1-up_6696|PDGFRA-down_5156 THBS1-down_7057|PDGFRA-down_5156 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04060	hsa04514	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CCL11-up NCAM1-up|CCL11-up SELL-down|CCL11-up VCAM1-up|CCL13-up NCAM1-up|CCL13-up VCAM1-up|CXCL12-up CD274-down|CXCL13-up CD274-down|PDGFRA-down CD274-down|CD27-up CD274-down|CD27-up CLDN1-up|CD27-up NCAM1-up|CD27-up SELL-down|CD27-up VCAM1-up|CXCL12-up CDH2-up|FIGF-down CDH2-up|FLT1-down CDH2-up|IL18R1-down CDH2-up|IL18RAP-down CDH2-up|PDGFRA-down CDH2-up|TGFB3-up CDH2-up|CXCL12-up CLDN5-down|FIGF-down CLDN5-down|FLT1-down CLDN5-down|CSF3R-down NCAM1-up|CXCL12-up NCAM1-up|CXCL12-up SELL-down|CXCL12-up VCAM1-up|CXCL12-up VTCN1-up|CXCL13-up NCAM1-up|CXCL13-up SELL-down|CXCL13-up VCAM1-up|CXCL14-up NCAM1-up|CXCL14-up SELL-down|CXCL14-up VCAM1-up|CXCL2-down SELL-down|CXCL2-down VCAM1-up|CXCL3-down SELL-down|CXCR2-down NCAM1-up|CXCR2-down SELL-down|CXCR2-down VCAM1-up|FIGF-down VCAM1-up|FLT1-down NCAM1-up|FLT1-down SELL-down|FLT1-down VCAM1-up|IL18R1-down NCAM1-up|IL18R1-down VCAM1-up|IL18RAP-down VCAM1-up|TGFB3-up ITGB8-up|LIFR-down VCAM1-up|PDGFRA-down NCAM1-up|TGFB3-up NCAM1-up|PDGFRA-down VCAM1-up|TGFB3-up VCAM1-up	CCL11-up_6356 NCAM1-up_4684|CCL11-up_6356 SELL-down_6402|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 NCAM1-up_4684|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CD274-down_29126|CXCL13-up_10563 CD274-down_29126|PDGFRA-down_5156 CD274-down_29126|CD27-up_939 CD274-down_29126|CD27-up_939 CLDN1-up_9076|CD27-up_939 NCAM1-up_4684|CD27-up_939 SELL-down_6402|CD27-up_939 VCAM1-up_7412|CXCL12-up_6387 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IL18R1-down_8809 CDH2-up_1000|IL18RAP-down_8807 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|CXCL12-up_6387 CLDN5-down_7122|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|CSF3R-down_1441 NCAM1-up_4684|CXCL12-up_6387 NCAM1-up_4684|CXCL12-up_6387 SELL-down_6402|CXCL12-up_6387 VCAM1-up_7412|CXCL12-up_6387 VTCN1-up_79679|CXCL13-up_10563 NCAM1-up_4684|CXCL13-up_10563 SELL-down_6402|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 NCAM1-up_4684|CXCL14-up_9547 SELL-down_6402|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 SELL-down_6402|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 SELL-down_6402|CXCR2-down_3579 NCAM1-up_4684|CXCR2-down_3579 SELL-down_6402|CXCR2-down_3579 VCAM1-up_7412|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 NCAM1-up_4684|FLT1-down_2321 SELL-down_6402|FLT1-down_2321 VCAM1-up_7412|IL18R1-down_8809 NCAM1-up_4684|IL18R1-down_8809 VCAM1-up_7412|IL18RAP-down_8807 VCAM1-up_7412|TGFB3-up_7043 ITGB8-up_3696|LIFR-down_3977 VCAM1-up_7412|PDGFRA-down_5156 NCAM1-up_4684|TGFB3-up_7043 NCAM1-up_4684|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04060	hsa04550	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0	CCL11-up IGF1-up|CCL11-up JAK1-down|CD27-up IGF1-up|CD27-up JAK1-down|CSF3R-down JAK1-down|CSF3R-down LIFR-down|CXCL12-up ID1-down|CXCL12-up IGF1-up|CXCL12-up JAK1-down|CXCL12-up SOX2-up|CXCL14-up IGF1-up|CXCL2-down IGF1-up|CXCR2-down IGF1-up|FIGF-down IGF1-up|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down IGF1-up|FLT1-down JAK1-down|FLT1-down SOX2-up|PDGFRA-down FZD5-down|PDGFRA-down ID1-down|TGFB3-up ID1-down|TNFRSF19-up ID1-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down JAK1-down|PDGFRA-down SOX2-up	CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JAK1-down_3716|CD27-up_939 IGF1-up_3479|CD27-up_939 JAK1-down_3716|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 LIFR-down_3977|CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 SOX2-up_6657|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 IGF1-up_3479|CXCR2-down_3579 IGF1-up_3479|FIGF-down_2277 IGF1-up_3479|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 SOX2-up_6657|PDGFRA-down_5156 FZD5-down_7855|PDGFRA-down_5156 ID1-down_3397|TGFB3-up_7043 ID1-down_3397|TNFRSF19-up_55504 ID1-down_3397|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 SOX2-up_6657
hsa04060	hsa04610	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0	CCL11-up CFH-up|CCL11-up F3-down|CCL11-up SERPINE1-down|FLT1-down CFH-up|PDGFRA-down CFH-up|CXCL12-up F3-down|CXCL12-up PLAU-up|CXCL12-up SERPINE1-down|CXCL12-up TFPI-down|CXCL14-up SERPINE1-down|CXCL2-down PLAU-up|CXCL3-down F3-down|CXCL3-down PLAU-up|CXCR2-down F3-down|CXCR2-down SERPINE1-down|FLT1-down F3-down|IL1R2-down F3-down|PDGFRA-down F3-down|FIGF-down PLAU-up|FIGF-down SERPINE1-down|FLT1-down PLAU-up|FLT1-down SERPINE1-down|FLT1-down TFPI-down|PDGFRA-down PLAU-up|TGFB3-up PLAU-up|TGFB3-up SERPINE1-down	CCL11-up_6356 CFH-up_3075|CCL11-up_6356 F3-down_2152|CCL11-up_6356 SERPINE1-down_5054|FLT1-down_2321 CFH-up_3075|PDGFRA-down_5156 CFH-up_3075|CXCL12-up_6387 F3-down_2152|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 TFPI-down_7035|CXCL14-up_9547 SERPINE1-down_5054|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 F3-down_2152|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 F3-down_2152|CXCR2-down_3579 SERPINE1-down_5054|FLT1-down_2321 F3-down_2152|IL1R2-down_7850 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 SERPINE1-down_5054|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TFPI-down_7035|PDGFRA-down_5156 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SERPINE1-down_5054
hsa04060	hsa04630	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0	CCL11-up JAK1-down|CCL11-up SOCS3-down|CD27-up CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|FLT1-down CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|CD27-up JAK1-down|CXCL12-up JAK1-down|CXCL12-up MCL1-down|CXCL12-up SOCS3-down|CXCL13-up MCL1-down|CXCL13-up SOCS3-down|CXCL2-down SOCS3-down|CXCL3-down SOCS3-down|CXCR2-down MCL1-down|CXCR2-down SOCS3-down|FLT1-down JAK1-down|FLT1-down MCL1-down|FLT1-down SOCS3-down|IL18R1-down SOCS3-down|IL18RAP-down SOCS3-down|IL1R2-down SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down MCL1-down|TNFRSF21-up MCL1-down|PDGFRA-down SOCS3-down	CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 SOCS3-down_9021|CD27-up_939 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|FLT1-down_2321 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD27-up_939 JAK1-down_3716|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 SOCS3-down_9021|CXCL13-up_10563 MCL1-down_4170|CXCL13-up_10563 SOCS3-down_9021|CXCL2-down_2920 SOCS3-down_9021|CXCL3-down_2921 SOCS3-down_9021|CXCR2-down_3579 MCL1-down_4170|CXCR2-down_3579 SOCS3-down_9021|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 SOCS3-down_9021|IL18R1-down_8809 SOCS3-down_9021|IL18RAP-down_8807 SOCS3-down_9021|IL1R2-down_7850 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 MCL1-down_4170|TNFRSF21-up_27242 MCL1-down_4170|PDGFRA-down_5156 SOCS3-down_9021
hsa04060	hsa04668	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	CCL11-up JUN-down|CCL11-up SOCS3-down|CCL11-up VCAM1-up|CCL13-up VCAM1-up|CD27-up JUN-down|CD27-up VCAM1-up|CSF3R-down JUN-down|CSF3R-down SOCS3-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL12-up VCAM1-up|CXCL13-up SOCS3-down|CXCL13-up VCAM1-up|CXCL14-up JUN-down|CXCL14-up VCAM1-up|CXCR2-down JUN-down|CXCR2-down SOCS3-down|CXCR2-down VCAM1-up|FIGF-down JUN-down|FIGF-down VCAM1-up|FLT1-down JUN-down|FLT1-down SOCS3-down|FLT1-down VCAM1-up|IL18RAP-down JUN-down|IL18RAP-down SOCS3-down|IL18RAP-down VCAM1-up|IL1R2-down SOCS3-down|LIFR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|TNFRSF21-up JUN-down|LIFR-down SOCS3-down|LIFR-down VCAM1-up|PDGFRA-down MAP3K8-down|PDGFRA-down SOCS3-down|PDGFRA-down VCAM1-up|TGFB3-up VCAM1-up	CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SOCS3-down_9021|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 VCAM1-up_7412|CD27-up_939 JUN-down_3725|CD27-up_939 VCAM1-up_7412|CSF3R-down_1441 JUN-down_3725|CSF3R-down_1441 SOCS3-down_9021|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL12-up_6387 VCAM1-up_7412|CXCL13-up_10563 SOCS3-down_9021|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 VCAM1-up_7412|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SOCS3-down_9021|CXCR2-down_3579 VCAM1-up_7412|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|FLT1-down_2321 VCAM1-up_7412|IL18RAP-down_8807 JUN-down_3725|IL18RAP-down_8807 SOCS3-down_9021|IL18RAP-down_8807 VCAM1-up_7412|IL1R2-down_7850 SOCS3-down_9021|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|LIFR-down_3977 SOCS3-down_9021|LIFR-down_3977 VCAM1-up_7412|PDGFRA-down_5156 MAP3K8-down_1326|PDGFRA-down_5156 SOCS3-down_9021|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04060	hsa04670	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CCL11-up CXCL12-up|CCL11-up MMP2-up|CCL11-up VCAM1-up|CCL13-up CXCL12-up|CCL13-up MMP2-up|CCL13-up VCAM1-up|CD27-up CLDN1-up|CD27-up CXCL12-up|CD27-up VCAM1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|CSF3R-down CXCL12-up|CXCL12-up CXCL2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up LIFR-down|CXCL12-up PDGFRA-down|CXCL13-up MMP2-up|CXCL13-up VCAM1-up|CXCL14-up MMP2-up|CXCL14-up VCAM1-up|CXCL2-down MMP2-up|CXCL2-down VCAM1-up|CXCL3-down MMP2-up|CXCR2-down MMP2-up|CXCR2-down VCAM1-up|FIGF-down MMP2-up|FIGF-down VCAM1-up|FLT1-down MMP2-up|FLT1-down VCAM1-up|IL18R1-down VCAM1-up|IL18RAP-down VCAM1-up|LIFR-down VCAM1-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down VCAM1-up|TGFB3-up THY1-up|TGFB3-up VCAM1-up	CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 MMP2-up_4313|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP2-up_4313|CCL13-up_6357 VCAM1-up_7412|CD27-up_939 CLDN1-up_9076|CD27-up_939 CXCL12-up_6387|CD27-up_939 VCAM1-up_7412|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|CSF3R-down_1441 CXCL12-up_6387|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 PDGFRA-down_5156|CXCL13-up_10563 MMP2-up_4313|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 VCAM1-up_7412|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 VCAM1-up_7412|IL18R1-down_8809 VCAM1-up_7412|IL18RAP-down_8807 VCAM1-up_7412|LIFR-down_3977 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 THY1-up_7070|TGFB3-up_7043 VCAM1-up_7412
hsa04060	hsa04915	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	CCL11-up HBEGF-down|CCL11-up JUN-down|CCL11-up MMP2-up|CCL13-up MMP2-up|CD27-up JUN-down|CSF3R-down JUN-down|CXCL12-up GABBR2-up|CXCL12-up HBEGF-down|CXCL12-up JUN-down|CXCL12-up MMP2-up|CXCL13-up MMP2-up|CXCL14-up HBEGF-down|CXCL14-up JUN-down|CXCL14-up MMP2-up|CXCL2-down HSPA1A-down|CXCL2-down JUN-down|CXCL2-down KCNJ5-up|CXCL2-down MMP2-up|CXCL3-down HBEGF-down|CXCL3-down JUN-down|CXCL3-down MMP2-up|CXCR2-down JUN-down|CXCR2-down MMP2-up|FIGF-down HBEGF-down|FIGF-down JUN-down|FIGF-down MMP2-up|FLT1-down HBEGF-down|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JUN-down|FLT1-down MMP2-up|IL1R2-down HBEGF-down|LIFR-down HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|IL18R1-down JUN-down|IL18RAP-down JUN-down|LIFR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|TNFRSF21-up JUN-down|PDGFRA-down MMP2-up|TGFB3-up MMP2-up	CCL11-up_6356 HBEGF-down_1839|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 MMP2-up_4313|CD27-up_939 JUN-down_3725|CSF3R-down_1441 JUN-down_3725|CXCL12-up_6387 GABBR2-up_9568|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP2-up_4313|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 HBEGF-down_1839|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP2-up_4313|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 KCNJ5-up_3762|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP2-up_4313|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP2-up_4313|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|IL1R2-down_7850 HBEGF-down_1839|LIFR-down_3977 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|IL18R1-down_8809 JUN-down_3725|IL18RAP-down_8807 JUN-down_3725|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313
hsa04060	hsa04921	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Oxytocin signaling pathway - Homo sapiens (human)	JUN,NPR1,CCND1,GUCY1A3,KCNJ5,PRKAA2	0.019	CCL11-up JUN-down|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CD27-up JUN-down|CSF3R-down JUN-down|CXCL12-up JUN-down|CXCL14-up JUN-down|CXCL2-down JUN-down|CXCL2-down KCNJ5-up|CXCL3-down JUN-down|CXCR2-down JUN-down|FIGF-down JUN-down|FLT1-down JUN-down|PDGFRA-down GUCY1A3-up|IL18R1-down JUN-down|IL18RAP-down JUN-down|LIFR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|TNFRSF21-up JUN-down	CCL11-up_6356 JUN-down_3725|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CD27-up_939 JUN-down_3725|CSF3R-down_1441 JUN-down_3725|CXCL12-up_6387 JUN-down_3725|CXCL14-up_9547 JUN-down_3725|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 KCNJ5-up_3762|CXCL3-down_2921 JUN-down_3725|CXCR2-down_3579 JUN-down_3725|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 JUN-down_3725|PDGFRA-down_5156 GUCY1A3-up_2982|IL18R1-down_8809 JUN-down_3725|IL18RAP-down_8807 JUN-down_3725|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725
hsa04060	hsa04933	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CCL11-up COL1A2-up|CCL11-up F3-down|CCL11-up JUN-down|CCL11-up MMP2-up|CCL11-up SERPINE1-down|CCL11-up VCAM1-up|CCL13-up MMP2-up|CCL13-up VCAM1-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|CD27-up JUN-down|CD27-up VCAM1-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|FLT1-down COL1A1-up|PDGFRA-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|FLT1-down COL1A2-up|PDGFRA-down COL1A2-up|CXCL12-up COL3A1-up|FLT1-down COL3A1-up|PDGFRA-down COL3A1-up|CSF3R-down JUN-down|CXCL12-up F3-down|CXCL12-up JUN-down|CXCL12-up MMP2-up|CXCL12-up SERPINE1-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|CXCL13-up MMP2-up|CXCL13-up VCAM1-up|CXCL14-up JUN-down|CXCL14-up MMP2-up|CXCL14-up SERPINE1-down|CXCL14-up VCAM1-up|CXCL2-down JUN-down|CXCL2-down MMP2-up|CXCL2-down VCAM1-up|CXCL3-down F3-down|CXCL3-down JUN-down|CXCL3-down MMP2-up|CXCR2-down F3-down|CXCR2-down JUN-down|CXCR2-down MMP2-up|CXCR2-down SERPINE1-down|CXCR2-down VCAM1-up|FLT1-down F3-down|IL1R2-down F3-down|PDGFRA-down F3-down|FLT1-down JUN-down|FLT1-down MMP2-up|FLT1-down SERPINE1-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|IL18R1-down JUN-down|IL18R1-down VCAM1-up|IL18RAP-down JUN-down|IL18RAP-down VCAM1-up|LIFR-down JUN-down|PDGFRA-down JUN-down|TNFRSF21-up JUN-down|LIFR-down VCAM1-up|PDGFRA-down MMP2-up|PDGFRA-down TGFB3-up|PDGFRA-down VCAM1-up	CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 F3-down_2152|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP2-up_4313|CCL11-up_6356 SERPINE1-down_5054|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 MMP2-up_4313|CCL13-up_6357 VCAM1-up_7412|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|CD27-up_939 JUN-down_3725|CD27-up_939 VCAM1-up_7412|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|CSF3R-down_1441 JUN-down_3725|CXCL12-up_6387 F3-down_2152|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|CXCL13-up_10563 MMP2-up_4313|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 SERPINE1-down_5054|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 F3-down_2152|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 F3-down_2152|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 SERPINE1-down_5054|CXCR2-down_3579 VCAM1-up_7412|FLT1-down_2321 F3-down_2152|IL1R2-down_7850 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|IL18R1-down_8809 JUN-down_3725|IL18R1-down_8809 VCAM1-up_7412|IL18RAP-down_8807 JUN-down_3725|IL18RAP-down_8807 VCAM1-up_7412|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|LIFR-down_3977 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 VCAM1-up_7412
hsa04060	hsa04974	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CCL11-up COL1A2-up|CD27-up MME-down|TGFB3-up COL10A1-up|TGFB3-up COL14A1-up|CXCL12-up COL18A1-up|CXCR2-down COL18A1-up|FIGF-down COL18A1-up|FLT1-down COL18A1-up|TGFB3-up COL18A1-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|FIGF-down COL1A1-up|FLT1-down COL1A1-up|PDGFRA-down COL1A1-up|TGFB3-up COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|PDGFRA-down COL1A2-up|TGFB3-up COL1A2-up|CXCL12-up COL3A1-up|FLT1-down COL3A1-up|PDGFRA-down COL3A1-up|TGFB3-up COL3A1-up|FLT1-down COL5A1-up|PDGFRA-down COL5A1-up|TGFB3-up COL5A1-up|TGFB3-up COL5A2-up|PDGFRA-down COL6A1-up|TGFB3-up COL6A1-up|PDGFRA-down COL6A3-up|TGFB3-up COL6A3-up|CXCL12-up MME-down|CXCL13-up MME-down|FLT1-down MME-down|PDGFRA-down MME-down|TNFRSF21-up MME-down	CCL11-up_6356 COL1A2-up_1278|CD27-up_939 MME-down_4311|TGFB3-up_7043 COL10A1-up_1300|TGFB3-up_7043 COL14A1-up_7373|CXCL12-up_6387 COL18A1-up_80781|CXCR2-down_3579 COL18A1-up_80781|FIGF-down_2277 COL18A1-up_80781|FLT1-down_2321 COL18A1-up_80781|TGFB3-up_7043 COL18A1-up_80781|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|TGFB3-up_7043 COL3A1-up_1281|FLT1-down_2321 COL5A1-up_1289|PDGFRA-down_5156 COL5A1-up_1289|TGFB3-up_7043 COL5A1-up_1289|TGFB3-up_7043 COL5A2-up_1290|PDGFRA-down_5156 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|CXCL12-up_6387 MME-down_4311|CXCL13-up_10563 MME-down_4311|FLT1-down_2321 MME-down_4311|PDGFRA-down_5156 MME-down_4311|TNFRSF21-up_27242 MME-down_4311
hsa04060	hsa05145	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.038	CCL11-up JAK1-down|CD27-up JAK1-down|CSF3R-down JAK1-down|CXCL12-up JAK1-down|CXCL12-up LDLR-down|CXCL12-up TGFB3-up|CXCL2-down HSPA1A-down|CXCL2-down LDLR-down|CXCR2-down LDLR-down|FIGF-down TGFB3-up|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JAK1-down|FLT1-down LDLR-down|FLT1-down TGFB3-up|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|LIFR-down JAK1-down|PDGFRA-down JAK1-down|PDGFRA-down TGFB3-up	CCL11-up_6356 JAK1-down_3716|CD27-up_939 JAK1-down_3716|CSF3R-down_1441 JAK1-down_3716|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LDLR-down_3949|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 LDLR-down_3949|CXCR2-down_3579 LDLR-down_3949|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 LDLR-down_3949|FLT1-down_2321 TGFB3-up_7043|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|LIFR-down_3977 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 TGFB3-up_7043
hsa04060	hsa05146	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CCL11-up COL1A2-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|FIGF-down COL1A1-up|FLT1-down COL1A1-up|PDGFRA-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|FIGF-down COL1A2-up|FLT1-down COL1A2-up|PDGFRA-down COL1A2-up|CXCL12-up COL3A1-up|FLT1-down COL3A1-up|PDGFRA-down COL3A1-up|CXCL12-up TGFB3-up|CXCL2-down IL1R2-down|CXCR2-down IL1R2-down|FIGF-down TGFB3-up|FLT1-down TGFB3-up|IL18R1-down IL1R2-down|IL18RAP-down IL1R2-down|PDGFRA-down TGFB3-up	CCL11-up_6356 COL1A2-up_1278|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|FIGF-down_2277 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|FIGF-down_2277 COL1A2-up_1278|FLT1-down_2321 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 IL1R2-down_7850|CXCR2-down_3579 IL1R2-down_7850|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 TGFB3-up_7043|IL18R1-down_8809 IL1R2-down_7850|IL18RAP-down_8807 IL1R2-down_7850|PDGFRA-down_5156 TGFB3-up_7043
hsa04060	hsa05152	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0	CCL11-up JAK1-down|CD27-up JAK1-down|CXCL12-up CD74-up|CXCL14-up CD74-up|CXCR2-down CD74-up|FIGF-down CD74-up|IL18R1-down CD74-up|IL18RAP-down CD74-up|CXCR2-down CLEC4E-down|IL1R2-down CLEC4E-down|CSF3R-down JAK1-down|CXCL12-up JAK1-down|CXCL12-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down JAK1-down|FLT1-down TGFB3-up|LIFR-down JAK1-down|PDGFRA-down JAK1-down|PDGFRA-down TGFB3-up	CCL11-up_6356 JAK1-down_3716|CD27-up_939 JAK1-down_3716|CXCL12-up_6387 CD74-up_972|CXCL14-up_9547 CD74-up_972|CXCR2-down_3579 CD74-up_972|FIGF-down_2277 CD74-up_972|IL18R1-down_8809 CD74-up_972|IL18RAP-down_8807 CD74-up_972|CXCR2-down_3579 CLEC4E-down_26253|IL1R2-down_7850 CLEC4E-down_26253|CSF3R-down_1441 JAK1-down_3716|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 TGFB3-up_7043|LIFR-down_3977 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 TGFB3-up_7043
hsa04060	hsa05166	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up VCAM1-up|CCL13-up VCAM1-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|FLT1-down CCND2-up|CD27-up JAK1-down|CD27-up JUN-down|CD27-up VCAM1-up|CSF3R-down JAK1-down|CSF3R-down JUN-down|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up MYB-up|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|CXCL13-up VCAM1-up|CXCL14-up JUN-down|CXCL14-up VCAM1-up|CXCL2-down IL1R2-down|CXCL2-down JUN-down|CXCL2-down MYB-up|CXCL2-down VCAM1-up|CXCL3-down JUN-down|CXCR2-down IL1R2-down|CXCR2-down JUN-down|CXCR2-down VCAM1-up|FIGF-down JUN-down|FIGF-down PDGFRA-down|FIGF-down TGFB3-up|FIGF-down VCAM1-up|FLT1-down FZD5-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MYB-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|IL18R1-down IL1R2-down|IL18R1-down JUN-down|IL18R1-down VCAM1-up|IL18RAP-down IL1R2-down|IL18RAP-down JUN-down|IL18RAP-down VCAM1-up|LIFR-down JAK1-down|LIFR-down JUN-down|TNFRSF21-up JUN-down|LIFR-down VCAM1-up	CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 VCAM1-up_7412|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|FLT1-down_2321 CCND2-up_894|CD27-up_939 JAK1-down_3716|CD27-up_939 JUN-down_3725|CD27-up_939 VCAM1-up_7412|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 JUN-down_3725|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 IL1R2-down_7850|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MYB-up_4602|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 JUN-down_3725|CXCR2-down_3579 IL1R2-down_7850|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 VCAM1-up_7412|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MYB-up_4602|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|IL18R1-down_8809 IL1R2-down_7850|IL18R1-down_8809 JUN-down_3725|IL18R1-down_8809 VCAM1-up_7412|IL18RAP-down_8807 IL1R2-down_7850|IL18RAP-down_8807 JUN-down_3725|IL18RAP-down_8807 VCAM1-up_7412|LIFR-down_3977 JAK1-down_3716|LIFR-down_3977 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|LIFR-down_3977 VCAM1-up_7412
hsa04060	hsa05168	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up SOCS3-down|CD27-up JAK1-down|CD27-up JUN-down|CXCL12-up CD74-up|CXCL14-up CD74-up|CXCR2-down CD74-up|FIGF-down CD74-up|IL18R1-down CD74-up|IL18RAP-down CD74-up|CSF3R-down JAK1-down|CSF3R-down JUN-down|CSF3R-down SOCS3-down|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL13-up SOCS3-down|CXCL14-up JUN-down|CXCL2-down JUN-down|CXCL2-down SOCS3-down|CXCL3-down JUN-down|CXCL3-down SOCS3-down|CXCR2-down JUN-down|CXCR2-down SOCS3-down|FIGF-down JUN-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IL18R1-down JUN-down|IL18R1-down SOCS3-down|IL18RAP-down JUN-down|IL18RAP-down SOCS3-down|IL1R2-down SOCS3-down|LIFR-down JAK1-down|PDGFRA-down JAK1-down|LIFR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|TNFRSF21-up JUN-down|LIFR-down SOCS3-down|PDGFRA-down SOCS3-down	CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SOCS3-down_9021|CD27-up_939 JAK1-down_3716|CD27-up_939 JUN-down_3725|CXCL12-up_6387 CD74-up_972|CXCL14-up_9547 CD74-up_972|CXCR2-down_3579 CD74-up_972|FIGF-down_2277 CD74-up_972|IL18R1-down_8809 CD74-up_972|IL18RAP-down_8807 CD74-up_972|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 JUN-down_3725|CSF3R-down_1441 SOCS3-down_9021|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL13-up_10563 SOCS3-down_9021|CXCL14-up_9547 JUN-down_3725|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 SOCS3-down_9021|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SOCS3-down_9021|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IL18R1-down_8809 JUN-down_3725|IL18R1-down_8809 SOCS3-down_9021|IL18RAP-down_8807 JUN-down_3725|IL18RAP-down_8807 SOCS3-down_9021|IL1R2-down_7850 SOCS3-down_9021|LIFR-down_3977 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|LIFR-down_3977 SOCS3-down_9021|PDGFRA-down_5156 SOCS3-down_9021
hsa04060	hsa05200	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.001	CCL11-up CXCL12-up|CCL11-up IGF1-up|CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up MMP1-up|CCL11-up MMP2-up|CCL13-up CXCL12-up|CCL13-up MMP1-up|CCL13-up MMP2-up|CD27-up CCND1-up|CXCR2-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|CD27-up CXCL12-up|CD27-up IGF1-up|CD27-up JAK1-down|CD27-up JUN-down|CXCL12-up CXCL2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL12-up FLT1-down|CXCL12-up LIFR-down|CXCL13-up MMP1-up|CXCL13-up MMP2-up|CXCL14-up IGF1-up|CXCL14-up JUN-down|CXCL14-up MMP1-up|CXCL14-up MMP2-up|CXCL2-down IGF1-up|CXCL2-down JUN-down|CXCL2-down MMP1-up|CXCL2-down MMP2-up|CXCL3-down JUN-down|CXCL3-down MMP2-up|CXCR2-down IGF1-up|CXCR2-down JUN-down|CXCR2-down MMP1-up|CXCR2-down MMP2-up|FLT1-down EDNRB-down|FLT1-down FGF14-up|FLT1-down FZD5-down|FLT1-down IGF1-up|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down ZBTB16-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|TNFRSF19-up IGF1-up|IL18R1-down JUN-down|IL18RAP-down JUN-down|LIFR-down JAK1-down|LIFR-down JUN-down|TNFRSF21-up JUN-down	CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP1-up_4312|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP1-up_4312|CCL13-up_6357 MMP2-up_4313|CD27-up_939 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|CD27-up_939 CXCL12-up_6387|CD27-up_939 IGF1-up_3479|CD27-up_939 JAK1-down_3716|CD27-up_939 JUN-down_3725|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 LIFR-down_3977|CXCL13-up_10563 MMP1-up_4312|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP1-up_4312|CXCL14-up_9547 MMP2-up_4313|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP1-up_4312|CXCR2-down_3579 MMP2-up_4313|FLT1-down_2321 EDNRB-down_1910|FLT1-down_2321 FGF14-up_2259|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 ZBTB16-down_7704|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|IL18R1-down_8809 JUN-down_3725|IL18RAP-down_8807 JUN-down_3725|LIFR-down_3977 JAK1-down_3716|LIFR-down_3977 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725
hsa04060	hsa05202	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	CCL11-up IGF1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|CD27-up IGF1-up|CXCL12-up IGF1-up|CXCL12-up PLAU-up|CXCL12-up PROM1-up|CXCL12-up ZBTB16-down|CXCL14-up IGF1-up|CXCL14-up NFKBIZ-down|CXCL2-down IGF1-up|CXCL2-down IL1R2-down|CXCL2-down PLAU-up|CXCL3-down PLAU-up|CXCR2-down FLT1-down|CXCR2-down IGF1-up|CXCR2-down IL1R2-down|CXCR2-down PROM1-up|FIGF-down FLT1-down|FIGF-down IGF1-up|FIGF-down PLAU-up|FIGF-down PROM1-up|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|IL18R1-down IL1R2-down|IL18RAP-down IL1R2-down|PDGFRA-down PLAU-up|PDGFRA-down PROM1-up|PDGFRA-down ZBTB16-down|TGFB3-up PLAU-up|TGFB3-up SIX1-up	CCL11-up_6356 IGF1-up_3479|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 PROM1-up_8842|CXCL12-up_6387 ZBTB16-down_7704|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 NFKBIZ-down_64332|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IL1R2-down_7850|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 IL1R2-down_7850|CXCR2-down_3579 PROM1-up_8842|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 PROM1-up_8842|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|IL18R1-down_8809 IL1R2-down_7850|IL18RAP-down_8807 IL1R2-down_7850|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 PROM1-up_8842|PDGFRA-down_5156 ZBTB16-down_7704|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SIX1-up_6495
hsa04060	hsa05205	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	FLT1-down ANK2-up|PDGFRA-down ANK2-up|CCL11-up HBEGF-down|CCL11-up IGF1-up|CCL11-up MMP2-up|CCL13-up MMP2-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CD27-up IGF1-up|CXCL12-up HBEGF-down|CXCL12-up IGF1-up|CXCL12-up MMP2-up|CXCL12-up PLAU-up|CXCL12-up THBS1-down|CXCL13-up MMP2-up|CXCL14-up HBEGF-down|CXCL14-up IGF1-up|CXCL14-up MMP2-up|CXCL14-up THBS1-down|CXCL2-down IGF1-up|CXCL2-down MMP2-up|CXCL2-down PLAU-up|CXCL3-down HBEGF-down|CXCL3-down MMP2-up|CXCL3-down PLAU-up|CXCR2-down IGF1-up|CXCR2-down MMP2-up|CXCR2-down THBS1-down|FIGF-down HBEGF-down|FIGF-down IGF1-up|FIGF-down MMP2-up|FIGF-down PLAU-up|FIGF-down THBS1-down|FLT1-down FZD5-down|FLT1-down HBEGF-down|FLT1-down IGF1-up|FLT1-down MMP2-up|FLT1-down PLAU-up|FLT1-down THBS1-down|PDGFRA-down FZD5-down|IL1R2-down HBEGF-down|LIFR-down HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down PLAU-up|PDGFRA-down THBS1-down|TGFB3-up PLAU-up|TGFB3-up THBS1-down	FLT1-down_2321 ANK2-up_287|PDGFRA-down_5156 ANK2-up_287|CCL11-up_6356 HBEGF-down_1839|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 MMP2-up_4313|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 THBS1-down_7057|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 HBEGF-down_1839|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 THBS1-down_7057|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 MMP2-up_4313|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 THBS1-down_7057|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 THBS1-down_7057|PDGFRA-down_5156 FZD5-down_7855|IL1R2-down_7850 HBEGF-down_1839|LIFR-down_3977 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057
hsa04060	hsa05206	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|TGFB3-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|FLT1-down CCND2-up|TGFB3-up CCND2-up|CD27-up HMOX1-down|CXCL12-up HMOX1-down|CXCL12-up MCL1-down|CXCL12-up MMP16-up|CXCL12-up PLAU-up|CXCL12-up SERPINB5-up|CXCL12-up SOX4-up|CXCL12-up THBS1-down|CXCL12-up TNC-up|CXCL13-up MCL1-down|CXCL14-up SERPINB5-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down CYP24A1-up|CXCL2-down IRS2-down|CXCL2-down PLAU-up|CXCL3-down PLAU-up|CXCR2-down CYP24A1-up|CXCR2-down HMOX1-down|CXCR2-down MCL1-down|CXCR2-down THBS1-down|FIGF-down HMOX1-down|FIGF-down PDGFRA-down|FIGF-down PLAU-up|FIGF-down THBS1-down|FIGF-down TNC-up|FLT1-down HMOX1-down|FLT1-down IRS2-down|FLT1-down MCL1-down|FLT1-down MMP16-up|FLT1-down PDGFRA-down|FLT1-down PLAU-up|FLT1-down SERPINB5-up|FLT1-down THBS1-down|FLT1-down TNC-up|FLT1-down TP63-up|TNFRSF21-up HMOX1-down|TNFRSF21-up MCL1-down|TGFB3-up PLAU-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|FLT1-down_2321 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD27-up_939 HMOX1-down_3162|CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MMP16-up_4325|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SOX4-up_6659|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 MCL1-down_4170|CXCL14-up_9547 SERPINB5-up_5268|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 CYP24A1-up_1591|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 CYP24A1-up_1591|CXCR2-down_3579 HMOX1-down_3162|CXCR2-down_3579 MCL1-down_4170|CXCR2-down_3579 THBS1-down_7057|FIGF-down_2277 HMOX1-down_3162|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 TNC-up_3371|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 MMP16-up_4325|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 TNC-up_3371|FLT1-down_2321 TP63-up_8626|TNFRSF21-up_27242 HMOX1-down_3162|TNFRSF21-up_27242 MCL1-down_4170|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa04060	hsa05219	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCL11-up HBEGF-down|CCL11-up MMP1-up|CCL11-up MMP2-up|CCL13-up MMP1-up|CCL13-up MMP2-up|CD27-up CCND1-up|CSF3R-down CCND1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|FIGF-down CCND1-up|FLT1-down CCND1-up|LIFR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CXCL12-up HBEGF-down|CXCL12-up MMP1-up|CXCL12-up MMP2-up|CXCL12-up THBS1-down|CXCL13-up MMP1-up|CXCL13-up MMP2-up|CXCL14-up HBEGF-down|CXCL14-up MMP1-up|CXCL14-up MMP2-up|CXCL14-up THBS1-down|CXCL2-down MMP1-up|CXCL2-down MMP2-up|CXCL3-down HBEGF-down|CXCL3-down MMP2-up|CXCR2-down MMP1-up|CXCR2-down MMP2-up|CXCR2-down THBS1-down|FIGF-down HBEGF-down|FIGF-down MMP1-up|FIGF-down MMP2-up|FIGF-down THBS1-down|FLT1-down HBEGF-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down THBS1-down|IL1R2-down HBEGF-down|LIFR-down HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|PDGFRA-down MMP1-up|TGFB3-up MMP1-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down THBS1-down|TGFB3-up THBS1-down	CCL11-up_6356 HBEGF-down_1839|CCL11-up_6356 MMP1-up_4312|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 MMP1-up_4312|CCL13-up_6357 MMP2-up_4313|CD27-up_939 CCND1-up_595|CSF3R-down_1441 CCND1-up_595|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|FIGF-down_2277 CCND1-up_595|FLT1-down_2321 CCND1-up_595|LIFR-down_3977 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 MMP1-up_4312|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 THBS1-down_7057|CXCL13-up_10563 MMP1-up_4312|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 HBEGF-down_1839|CXCL14-up_9547 MMP1-up_4312|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 THBS1-down_7057|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 MMP1-up_4312|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 THBS1-down_7057|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 THBS1-down_7057|IL1R2-down_7850 HBEGF-down_1839|LIFR-down_3977 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|PDGFRA-down_5156 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057
hsa04060	hsa05323	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCL11-up CXCL12-up|CCL11-up JUN-down|CCL11-up MMP1-up|CCL13-up CXCL12-up|CCL13-up MMP1-up|CD27-up CTSK-up|CD27-up CXCL12-up|CD27-up JUN-down|CSF3R-down CXCL12-up|CSF3R-down JUN-down|CXCL14-up CTSK-up|CXCL12-up CXCL2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL12-up FIGF-down|CXCL12-up LIFR-down|CXCL12-up PDGFRA-down|CXCL13-up MMP1-up|CXCL14-up JUN-down|CXCL14-up MMP1-up|CXCL2-down JUN-down|CXCL2-down MMP1-up|CXCL3-down JUN-down|CXCR2-down FLT1-down|CXCR2-down JUN-down|CXCR2-down MMP1-up|FIGF-down FLT1-down|FIGF-down JUN-down|FIGF-down MMP1-up|FIGF-down TGFB3-up|IL18R1-down JUN-down|IL18RAP-down JUN-down|LIFR-down JUN-down|PDGFRA-down JUN-down|TNFRSF21-up JUN-down|PDGFRA-down MMP1-up|PDGFRA-down TGFB3-up	CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP1-up_4312|CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP1-up_4312|CD27-up_939 CTSK-up_1513|CD27-up_939 CXCL12-up_6387|CD27-up_939 JUN-down_3725|CSF3R-down_1441 CXCL12-up_6387|CSF3R-down_1441 JUN-down_3725|CXCL14-up_9547 CTSK-up_1513|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 PDGFRA-down_5156|CXCL13-up_10563 MMP1-up_4312|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP1-up_4312|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|CXCL3-down_2921 JUN-down_3725|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP1-up_4312|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 TGFB3-up_7043|IL18R1-down_8809 JUN-down_3725|IL18RAP-down_8807 JUN-down_3725|LIFR-down_3977 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TNFRSF21-up_27242 JUN-down_3725|PDGFRA-down_5156 MMP1-up_4312|PDGFRA-down_5156 TGFB3-up_7043
hsa04060	hsa05410	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.003	CCL11-up IGF1-up|CD27-up IGF1-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|CXCL14-up IGF1-up|CXCL2-down IGF1-up|CXCR2-down IGF1-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down ITGB4-up|PDGFRA-down TGFB3-up	CCL11-up_6356 IGF1-up_3479|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 IGF1-up_3479|CXCR2-down_3579 IGF1-up_3479|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 ITGB4-up_3691|PDGFRA-down_5156 TGFB3-up_7043
hsa04060	hsa05412	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.018	CXCL12-up CDH2-up|FIGF-down CDH2-up|FLT1-down CDH2-up|IL18R1-down CDH2-up|IL18RAP-down CDH2-up|PDGFRA-down CDH2-up|TGFB3-up CDH2-up|TGFB3-up DES-up|FLT1-down ITGB4-up|PDGFRA-down ITGB4-up|TGFB3-up ITGB8-up|PDGFRA-down TCF7L2-up|TGFB3-up TCF7L2-up	CXCL12-up_6387 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IL18R1-down_8809 CDH2-up_1000|IL18RAP-down_8807 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|FLT1-down_2321 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|PDGFRA-down_5156 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934
hsa04060	hsa05414	Cytokine-cytokine receptor interaction - Homo sapiens (human)	CSF3R,CXCL2,CXCL3,CXCR2,FIGF,FLT1,IL18R1,IL18RAP,IL1R2,LIFR,PDGFRA,CCL11,CCL13,CD27,CXCL12,CXCL13,CXCL14,TGFB3,TNFRSF19,TNFRSF21	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.015	FLT1-down ADRB1-down|CCL11-up IGF1-up|CD27-up IGF1-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|CXCL14-up IGF1-up|CXCL2-down IGF1-up|CXCR2-down IGF1-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|IL18R1-down IGF1-up|IL18RAP-down IGF1-up|LIFR-down IGF1-up|PDGFRA-down IGF1-up|TNFRSF19-up IGF1-up|PDGFRA-down ITGB4-up|PDGFRA-down TGFB3-up	FLT1-down_2321 ADRB1-down_153|CCL11-up_6356 IGF1-up_3479|CD27-up_939 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 IGF1-up_3479|CXCR2-down_3579 IGF1-up_3479|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|IL18R1-down_8809 IGF1-up_3479|IL18RAP-down_8807 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TNFRSF19-up_55504 IGF1-up_3479|PDGFRA-down_5156 ITGB4-up_3691|PDGFRA-down_5156 TGFB3-up_7043
hsa04062	hsa04064	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	0.001	ARRB1-down CXCL12-up|ARRB1-down CXCL2-down|CCL11-up CXCL12-up|CCL11-up VCAM1-up|CCL13-up CXCL3-down|CCL13-up CXCR2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL13-up VCAM1-up|CXCL14-up VCAM1-up|CXCL3-down PLAU-up|CXCR2-down GADD45B-down|CXCR2-down VCAM1-up	ARRB1-down_408 CXCL12-up_6387|ARRB1-down_408 CXCL2-down_2920|CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 CXCL3-down_2921|CCL13-up_6357 CXCR2-down_3579|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 VCAM1-up_7412|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 GADD45B-down_4616|CXCR2-down_3579 VCAM1-up_7412
hsa04062	hsa04068	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	0	ARRB1-down CCND1-up|ARRB1-down IGF1-up|ARRB1-down S1PR1-down|ARRB1-down TGFB3-up|CCL11-up IGF1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up GADD45B-down|CXCL12-up IGF1-up|CXCL12-up S1PR1-down|CXCL12-up SOD2-down|CXCL12-up TGFB3-up|CXCL13-up S1PR1-down|CXCL14-up IGF1-up|CXCL2-down GADD45B-down|CXCL2-down IGF1-up|CXCL2-down IRS2-down|CXCL2-down S1PR1-down|CXCL2-down SOD2-down|CXCL3-down S1PR1-down|CXCR2-down GADD45B-down|CXCR2-down IGF1-up|CXCR2-down S1PR1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 S1PR1-down_1901|ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 IGF1-up_3479|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 GADD45B-down_4616|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 S1PR1-down_1901|CXCL12-up_6387 SOD2-down_6648|CXCL12-up_6387 TGFB3-up_7043|CXCL13-up_10563 S1PR1-down_1901|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 GADD45B-down_4616|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 S1PR1-down_1901|CXCL2-down_2920 SOD2-down_6648|CXCL3-down_2921 S1PR1-down_1901|CXCR2-down_3579 GADD45B-down_4616|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 S1PR1-down_1901
hsa04062	hsa04080	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	0	ARRB1-down ADRB1-down|ARRB1-down APLNR-up|CXCL12-up APLNR-up|CXCL13-up APLNR-up|CXCL2-down APLNR-up|CXCL3-down APLNR-up|CXCR2-down APLNR-up|ARRB1-down EDNRB-down|ARRB1-down FPR1-down|ARRB1-down GABBR2-up|ARRB1-down RXFP1-down|ARRB1-down S1PR1-down|CCL11-up FPR1-down|CXCL12-up EDNRB-down|CXCL12-up FPR1-down|CXCL12-up FPR2-down|CXCL12-up GABBR2-up|CXCL12-up S1PR1-down|CXCL12-up VIPR1-down|CXCL13-up FPR1-down|CXCL13-up FPR2-down|CXCL13-up S1PR1-down|CXCL2-down FPR1-down|CXCL2-down FPR2-down|CXCL2-down S1PR1-down|CXCL3-down FPR1-down|CXCL3-down FPR2-down|CXCL3-down S1PR1-down|CXCR2-down FPR1-down|CXCR2-down FPR2-down|CXCR2-down GRIA1-down|CXCR2-down S1PR1-down	ARRB1-down_408 ADRB1-down_153|ARRB1-down_408 APLNR-up_187|CXCL12-up_6387 APLNR-up_187|CXCL13-up_10563 APLNR-up_187|CXCL2-down_2920 APLNR-up_187|CXCL3-down_2921 APLNR-up_187|CXCR2-down_3579 APLNR-up_187|ARRB1-down_408 EDNRB-down_1910|ARRB1-down_408 FPR1-down_2357|ARRB1-down_408 GABBR2-up_9568|ARRB1-down_408 RXFP1-down_59350|ARRB1-down_408 S1PR1-down_1901|CCL11-up_6356 FPR1-down_2357|CXCL12-up_6387 EDNRB-down_1910|CXCL12-up_6387 FPR1-down_2357|CXCL12-up_6387 FPR2-down_2358|CXCL12-up_6387 GABBR2-up_9568|CXCL12-up_6387 S1PR1-down_1901|CXCL12-up_6387 VIPR1-down_7433|CXCL13-up_10563 FPR1-down_2357|CXCL13-up_10563 FPR2-down_2358|CXCL13-up_10563 S1PR1-down_1901|CXCL2-down_2920 FPR1-down_2357|CXCL2-down_2920 FPR2-down_2358|CXCL2-down_2920 S1PR1-down_1901|CXCL3-down_2921 FPR1-down_2357|CXCL3-down_2921 FPR2-down_2358|CXCL3-down_2921 S1PR1-down_1901|CXCR2-down_3579 FPR1-down_2357|CXCR2-down_3579 FPR2-down_2358|CXCR2-down_3579 GRIA1-down_2890|CXCR2-down_3579 S1PR1-down_1901
hsa04062	hsa04115	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	0	ARRB1-down CCND1-up|ARRB1-down IGF1-up|CCL11-up IGF1-up|CCL11-up SERPINE1-down|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up GADD45B-down|CXCL12-up IGF1-up|CXCL12-up SERPINB5-up|CXCL12-up SERPINE1-down|CXCL12-up THBS1-down|CXCL14-up IGF1-up|CXCL14-up SERPINB5-up|CXCL14-up SERPINE1-down|CXCL14-up THBS1-down|CXCL2-down GADD45B-down|CXCL2-down IGF1-up|CXCR2-down GADD45B-down|CXCR2-down IGF1-up|CXCR2-down SERPINE1-down|CXCR2-down THBS1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 IGF1-up_3479|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 SERPINE1-down_5054|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 GADD45B-down_4616|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 THBS1-down_7057|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 SERPINB5-up_5268|CXCL14-up_9547 SERPINE1-down_5054|CXCL14-up_9547 THBS1-down_7057|CXCL2-down_2920 GADD45B-down_4616|CXCL2-down_2920 IGF1-up_3479|CXCR2-down_3579 GADD45B-down_4616|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 SERPINE1-down_5054|CXCR2-down_3579 THBS1-down_7057
hsa04062	hsa04151	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0	ARRB1-down CCND1-up|ARRB1-down FLT1-down|ARRB1-down IGF1-up|ARRB1-down JAK1-down|ARRB1-down PDGFRA-down|ARRB1-down SPP1-up|CCL11-up COL1A2-up|CCL11-up FLT1-down|CCL11-up IGF1-up|CCL11-up JAK1-down|CCL11-up SPP1-up|CCL13-up SPP1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|CXCL12-up COMP-up|CXCL12-up CSF3R-down|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up JAK1-down|CXCL12-up MCL1-down|CXCL12-up MYB-up|CXCL12-up PDGFRA-down|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL13-up MCL1-down|CXCL13-up SPP1-up|CXCL14-up IGF1-up|CXCL14-up SPP1-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down IGF1-up|CXCL2-down MYB-up|CXCL2-down SPP1-up|CXCR2-down FLT1-down|CXCR2-down IGF1-up|CXCR2-down MCL1-down|CXCR2-down SPP1-up|CXCR2-down THBS1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 SPP1-up_6696|CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 FLT1-down_2321|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 SPP1-up_6696|CCL13-up_6357 SPP1-up_6696|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|CXCL12-up_6387 COMP-up_1311|CXCL12-up_6387 CSF3R-down_1441|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 MCL1-down_4170|CXCL13-up_10563 SPP1-up_6696|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 SPP1-up_6696|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 MYB-up_4602|CXCL2-down_2920 SPP1-up_6696|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 MCL1-down_4170|CXCR2-down_3579 SPP1-up_6696|CXCR2-down_3579 THBS1-down_7057
hsa04062	hsa04310	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	ARRB1-down CCND1-up|ARRB1-down FZD5-down|ARRB1-down JUN-down|ARRB1-down SFRP2-up|ARRB1-down SFRP4-up|CCL11-up JUN-down|CCL11-up MMP7-up|CCL13-up MMP7-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up JUN-down|CXCL12-up MMP7-up|CXCL12-up SERPINF1-up|CXCL12-up SFRP2-up|CXCL14-up JUN-down|CXCL14-up MMP7-up|CXCL2-down JUN-down|CXCL2-down MMP7-up|CXCL3-down JUN-down|CXCL3-down MMP7-up|CXCR2-down JUN-down|CXCR2-down MMP7-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 SFRP2-up_6423|ARRB1-down_408 SFRP4-up_6424|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP7-up_4316|CCL13-up_6357 MMP7-up_4316|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP7-up_4316|CXCL12-up_6387 SERPINF1-up_5176|CXCL12-up_6387 SFRP2-up_6423|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP7-up_4316|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP7-up_4316|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP7-up_4316|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP7-up_4316
hsa04062	hsa04380	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0	ARRB1-down JAK1-down|ARRB1-down JUN-down|CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up SOCS3-down|CXCL12-up CTSK-up|CXCL14-up CTSK-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL13-up SOCS3-down|CXCL14-up JUN-down|CXCL2-down JUN-down|CXCL2-down SOCS3-down|CXCL3-down JUN-down|CXCL3-down SOCS3-down|CXCR2-down JUN-down|CXCR2-down SOCS3-down	ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 JUN-down_3725|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SOCS3-down_9021|CXCL12-up_6387 CTSK-up_1513|CXCL14-up_9547 CTSK-up_1513|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL13-up_10563 SOCS3-down_9021|CXCL14-up_9547 JUN-down_3725|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 SOCS3-down_9021|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SOCS3-down_9021
hsa04062	hsa04390	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.04	ARRB1-down CCND1-up|ARRB1-down FZD5-down|ARRB1-down TGFB3-up|CCL11-up SERPINE1-down|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up ID1-down|CXCL12-up SERPINE1-down|CXCL12-up SOX2-up|CXCL12-up TGFB3-up|CXCL14-up SERPINE1-down|CXCR2-down SERPINE1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 SERPINE1-down_5054|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 SOX2-up_6657|CXCL12-up_6387 TGFB3-up_7043|CXCL14-up_9547 SERPINE1-down_5054|CXCR2-down_3579 SERPINE1-down_5054
hsa04062	hsa04510	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0	ARRB1-down CCND1-up|ARRB1-down FLNC-up|ARRB1-down FLT1-down|ARRB1-down IGF1-up|ARRB1-down JUN-down|ARRB1-down PDGFRA-down|ARRB1-down SPP1-up|CCL11-up COL1A2-up|CCL11-up FLT1-down|CCL11-up IGF1-up|CCL11-up JUN-down|CCL11-up SPP1-up|CCL13-up SPP1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|CXCL12-up COMP-up|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up JUN-down|CXCL12-up PDGFRA-down|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL13-up SPP1-up|CXCL14-up IGF1-up|CXCL14-up JUN-down|CXCL14-up SPP1-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down IGF1-up|CXCL2-down JUN-down|CXCL2-down SPP1-up|CXCL3-down JUN-down|CXCR2-down FLT1-down|CXCR2-down IGF1-up|CXCR2-down JUN-down|CXCR2-down SPP1-up|CXCR2-down THBS1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FLNC-up_2318|ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 SPP1-up_6696|CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 FLT1-down_2321|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SPP1-up_6696|CCL13-up_6357 SPP1-up_6696|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|CXCL12-up_6387 COMP-up_1311|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 SPP1-up_6696|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 SPP1-up_6696|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SPP1-up_6696|CXCL3-down_2921 JUN-down_3725|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SPP1-up_6696|CXCR2-down_3579 THBS1-down_7057
hsa04062	hsa04512	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	ARRB1-down SPP1-up|CCL11-up COL1A2-up|CCL11-up SPP1-up|CCL13-up SPP1-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|CXCL12-up COMP-up|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL13-up SPP1-up|CXCL14-up SPP1-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down SPP1-up|CXCR2-down SPP1-up|CXCR2-down THBS1-down	ARRB1-down_408 SPP1-up_6696|CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 SPP1-up_6696|CCL13-up_6357 SPP1-up_6696|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|CXCL12-up_6387 COMP-up_1311|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 SPP1-up_6696|CXCL14-up_9547 SPP1-up_6696|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 SPP1-up_6696|CXCR2-down_3579 SPP1-up_6696|CXCR2-down_3579 THBS1-down_7057
hsa04062	hsa04514	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	ARRB1-down CD274-down|CCL11-up NCAM1-up|CCL11-up SELL-down|CCL11-up VCAM1-up|CCL13-up NCAM1-up|CCL13-up VCAM1-up|CXCL12-up CD274-down|CXCL13-up CD274-down|CXCL12-up CDH2-up|CXCL12-up CLDN5-down|CXCL12-up NCAM1-up|CXCL12-up SELL-down|CXCL12-up VCAM1-up|CXCL12-up VTCN1-up|CXCL13-up NCAM1-up|CXCL13-up SELL-down|CXCL13-up VCAM1-up|CXCL14-up NCAM1-up|CXCL14-up SELL-down|CXCL14-up VCAM1-up|CXCL2-down SELL-down|CXCL2-down VCAM1-up|CXCL3-down SELL-down|CXCR2-down NCAM1-up|CXCR2-down SELL-down|CXCR2-down VCAM1-up	ARRB1-down_408 CD274-down_29126|CCL11-up_6356 NCAM1-up_4684|CCL11-up_6356 SELL-down_6402|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 NCAM1-up_4684|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CD274-down_29126|CXCL13-up_10563 CD274-down_29126|CXCL12-up_6387 CDH2-up_1000|CXCL12-up_6387 CLDN5-down_7122|CXCL12-up_6387 NCAM1-up_4684|CXCL12-up_6387 SELL-down_6402|CXCL12-up_6387 VCAM1-up_7412|CXCL12-up_6387 VTCN1-up_79679|CXCL13-up_10563 NCAM1-up_4684|CXCL13-up_10563 SELL-down_6402|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 NCAM1-up_4684|CXCL14-up_9547 SELL-down_6402|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 SELL-down_6402|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 SELL-down_6402|CXCR2-down_3579 NCAM1-up_4684|CXCR2-down_3579 SELL-down_6402|CXCR2-down_3579 VCAM1-up_7412
hsa04062	hsa04550	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.002	ARRB1-down FZD5-down|ARRB1-down IGF1-up|ARRB1-down JAK1-down|CCL11-up IGF1-up|CCL11-up JAK1-down|CXCL12-up ID1-down|CXCL12-up IGF1-up|CXCL12-up JAK1-down|CXCL12-up LIFR-down|CXCL12-up SOX2-up|CXCL14-up IGF1-up|CXCL2-down IGF1-up|CXCR2-down IGF1-up	ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JAK1-down_3716|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JAK1-down_3716|CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 SOX2-up_6657|CXCL14-up_9547 IGF1-up_3479|CXCL2-down_2920 IGF1-up_3479|CXCR2-down_3579 IGF1-up_3479
hsa04062	hsa04610	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.001	CCL11-up CFH-up|CCL11-up F3-down|CCL11-up SERPINE1-down|CXCL12-up F3-down|CXCL12-up PLAU-up|CXCL12-up SERPINE1-down|CXCL12-up TFPI-down|CXCL14-up SERPINE1-down|CXCL2-down PLAU-up|CXCL3-down F3-down|CXCL3-down PLAU-up|CXCR2-down F3-down|CXCR2-down SERPINE1-down	CCL11-up_6356 CFH-up_3075|CCL11-up_6356 F3-down_2152|CCL11-up_6356 SERPINE1-down_5054|CXCL12-up_6387 F3-down_2152|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 TFPI-down_7035|CXCL14-up_9547 SERPINE1-down_5054|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 F3-down_2152|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 F3-down_2152|CXCR2-down_3579 SERPINE1-down_5054
hsa04062	hsa04630	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0	ARRB1-down CCND1-up|ARRB1-down JAK1-down|CCL11-up JAK1-down|CCL11-up SOCS3-down|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up CSF3R-down|CXCL12-up JAK1-down|CXCL12-up LIFR-down|CXCL12-up MCL1-down|CXCL12-up SOCS3-down|CXCL13-up MCL1-down|CXCL13-up SOCS3-down|CXCL2-down SOCS3-down|CXCL3-down SOCS3-down|CXCR2-down MCL1-down|CXCR2-down SOCS3-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 JAK1-down_3716|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 SOCS3-down_9021|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 CSF3R-down_1441|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 SOCS3-down_9021|CXCL13-up_10563 MCL1-down_4170|CXCL13-up_10563 SOCS3-down_9021|CXCL2-down_2920 SOCS3-down_9021|CXCL3-down_2921 SOCS3-down_9021|CXCR2-down_3579 MCL1-down_4170|CXCR2-down_3579 SOCS3-down_9021
hsa04062	hsa04668	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.001	ARRB1-down CXCL2-down|ARRB1-down JUN-down|CCL11-up JUN-down|CCL11-up SOCS3-down|CCL11-up VCAM1-up|CCL13-up VCAM1-up|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL12-up VCAM1-up|CXCL13-up SOCS3-down|CXCL13-up VCAM1-up|CXCL14-up JUN-down|CXCL14-up VCAM1-up|CXCR2-down JUN-down|CXCR2-down SOCS3-down|CXCR2-down VCAM1-up	ARRB1-down_408 CXCL2-down_2920|ARRB1-down_408 JUN-down_3725|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SOCS3-down_9021|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL12-up_6387 VCAM1-up_7412|CXCL13-up_10563 SOCS3-down_9021|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 VCAM1-up_7412|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SOCS3-down_9021|CXCR2-down_3579 VCAM1-up_7412
hsa04062	hsa04670	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	ARRB1-down CXCL12-up|CCL11-up CXCL12-up|CCL11-up MMP2-up|CCL11-up VCAM1-up|CCL13-up CXCL12-up|CCL13-up MMP2-up|CCL13-up VCAM1-up|CXCL12-up CXCL2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL13-up MMP2-up|CXCL13-up VCAM1-up|CXCL14-up MMP2-up|CXCL14-up VCAM1-up|CXCL2-down MMP2-up|CXCL2-down VCAM1-up|CXCL3-down MMP2-up|CXCR2-down MMP2-up|CXCR2-down VCAM1-up	ARRB1-down_408 CXCL12-up_6387|CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 MMP2-up_4313|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP2-up_4313|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL13-up_10563 MMP2-up_4313|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 VCAM1-up_7412
hsa04062	hsa04915	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	ARRB1-down GABBR2-up|ARRB1-down JUN-down|ARRB1-down KCNJ5-up|CCL11-up HBEGF-down|CCL11-up JUN-down|CCL11-up MMP2-up|CCL13-up MMP2-up|CXCL12-up GABBR2-up|CXCL12-up HBEGF-down|CXCL12-up JUN-down|CXCL12-up MMP2-up|CXCL13-up MMP2-up|CXCL14-up HBEGF-down|CXCL14-up JUN-down|CXCL14-up MMP2-up|CXCL2-down HSPA1A-down|CXCL2-down JUN-down|CXCL2-down KCNJ5-up|CXCL2-down MMP2-up|CXCL3-down HBEGF-down|CXCL3-down JUN-down|CXCL3-down MMP2-up|CXCR2-down JUN-down|CXCR2-down MMP2-up	ARRB1-down_408 GABBR2-up_9568|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 KCNJ5-up_3762|CCL11-up_6356 HBEGF-down_1839|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 MMP2-up_4313|CXCL12-up_6387 GABBR2-up_9568|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP2-up_4313|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 HBEGF-down_1839|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP2-up_4313|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 KCNJ5-up_3762|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP2-up_4313
hsa04062	hsa04933	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	ARRB1-down CCND1-up|ARRB1-down JUN-down|ARRB1-down TGFB3-up|CCL11-up COL1A2-up|CCL11-up F3-down|CCL11-up JUN-down|CCL11-up MMP2-up|CCL11-up SERPINE1-down|CCL11-up VCAM1-up|CCL13-up MMP2-up|CCL13-up VCAM1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|CXCL12-up COL3A1-up|CXCL12-up F3-down|CXCL12-up FIGF-down|CXCL12-up JUN-down|CXCL12-up MMP2-up|CXCL12-up SERPINE1-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|CXCL13-up MMP2-up|CXCL13-up VCAM1-up|CXCL14-up JUN-down|CXCL14-up MMP2-up|CXCL14-up SERPINE1-down|CXCL14-up VCAM1-up|CXCL2-down JUN-down|CXCL2-down MMP2-up|CXCL2-down VCAM1-up|CXCL3-down F3-down|CXCL3-down JUN-down|CXCL3-down MMP2-up|CXCR2-down F3-down|CXCR2-down JUN-down|CXCR2-down MMP2-up|CXCR2-down SERPINE1-down|CXCR2-down VCAM1-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 COL1A2-up_1278|CCL11-up_6356 F3-down_2152|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP2-up_4313|CCL11-up_6356 SERPINE1-down_5054|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 MMP2-up_4313|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|CXCL12-up_6387 F3-down_2152|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|CXCL13-up_10563 MMP2-up_4313|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 SERPINE1-down_5054|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 F3-down_2152|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 F3-down_2152|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 SERPINE1-down_5054|CXCR2-down_3579 VCAM1-up_7412
hsa04062	hsa04970	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	0.037	ARRB1-down ADRB1-down|ARRB1-down KCNMA1-up|CCL11-up MUC5B-up|CXCL2-down MUC5B-up|CXCL3-down MUC5B-up|CXCR2-down MUC5B-up	ARRB1-down_408 ADRB1-down_153|ARRB1-down_408 KCNMA1-up_3778|CCL11-up_6356 MUC5B-up_727897|CXCL2-down_2920 MUC5B-up_727897|CXCL3-down_2921 MUC5B-up_727897|CXCR2-down_3579 MUC5B-up_727897
hsa04062	hsa04974	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0.033	CCL11-up COL1A2-up|CXCL12-up COL18A1-up|CXCR2-down COL18A1-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|CXCL12-up COL3A1-up|CXCL12-up MME-down|CXCL13-up MME-down	CCL11-up_6356 COL1A2-up_1278|CXCL12-up_6387 COL18A1-up_80781|CXCR2-down_3579 COL18A1-up_80781|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|CXCL12-up_6387 MME-down_4311|CXCL13-up_10563 MME-down_4311
hsa04062	hsa05146	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	ARRB1-down TGFB3-up|CCL11-up COL1A2-up|CXCL12-up COL1A1-up|CXCL13-up COL1A1-up|CXCL14-up COL1A1-up|CXCL2-down COL1A1-up|CXCR2-down COL1A1-up|CXCL12-up COL1A2-up|CXCL14-up COL1A2-up|CXCL12-up COL3A1-up|CXCL12-up TGFB3-up|CXCL2-down IL1R2-down|CXCR2-down IL1R2-down	ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 COL1A2-up_1278|CXCL12-up_6387 COL1A1-up_1277|CXCL13-up_10563 COL1A1-up_1277|CXCL14-up_9547 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|CXCR2-down_3579 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL14-up_9547 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 IL1R2-down_7850|CXCR2-down_3579 IL1R2-down_7850
hsa04062	hsa05152	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.002	ARRB1-down JAK1-down|ARRB1-down TGFB3-up|CCL11-up JAK1-down|CXCL12-up CD74-up|CXCL14-up CD74-up|CXCR2-down CD74-up|CXCR2-down CLEC4E-down|CXCL12-up JAK1-down|CXCL12-up TGFB3-up	ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 JAK1-down_3716|CXCL12-up_6387 CD74-up_972|CXCL14-up_9547 CD74-up_972|CXCR2-down_3579 CD74-up_972|CXCR2-down_3579 CLEC4E-down_26253|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 TGFB3-up_7043
hsa04062	hsa05166	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.002	ARRB1-down CCND1-up|ARRB1-down FZD5-down|ARRB1-down JAK1-down|ARRB1-down JUN-down|ARRB1-down PDGFRA-down|ARRB1-down TGFB3-up|CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up VCAM1-up|CCL13-up VCAM1-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up MYB-up|CXCL12-up PDGFRA-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|CXCL13-up VCAM1-up|CXCL14-up JUN-down|CXCL14-up VCAM1-up|CXCL2-down IL1R2-down|CXCL2-down JUN-down|CXCL2-down MYB-up|CXCL2-down VCAM1-up|CXCL3-down JUN-down|CXCR2-down IL1R2-down|CXCR2-down JUN-down|CXCR2-down VCAM1-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 VCAM1-up_7412|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|CXCL13-up_10563 VCAM1-up_7412|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 VCAM1-up_7412|CXCL2-down_2920 IL1R2-down_7850|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MYB-up_4602|CXCL2-down_2920 VCAM1-up_7412|CXCL3-down_2921 JUN-down_3725|CXCR2-down_3579 IL1R2-down_7850|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 VCAM1-up_7412
hsa04062	hsa05168	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	ARRB1-down JAK1-down|ARRB1-down JUN-down|CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up SOCS3-down|CXCL12-up CD74-up|CXCL14-up CD74-up|CXCR2-down CD74-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL13-up SOCS3-down|CXCL14-up JUN-down|CXCL2-down JUN-down|CXCL2-down SOCS3-down|CXCL3-down JUN-down|CXCL3-down SOCS3-down|CXCR2-down JUN-down|CXCR2-down SOCS3-down	ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 JUN-down_3725|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 SOCS3-down_9021|CXCL12-up_6387 CD74-up_972|CXCL14-up_9547 CD74-up_972|CXCR2-down_3579 CD74-up_972|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL13-up_10563 SOCS3-down_9021|CXCL14-up_9547 JUN-down_3725|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 SOCS3-down_9021|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SOCS3-down_9021
hsa04062	hsa05200	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.006	ARRB1-down CCND1-up|ARRB1-down CXCL12-up|ARRB1-down EDNRB-down|ARRB1-down FZD5-down|ARRB1-down HHIP-down|ARRB1-down IGF1-up|ARRB1-down JAK1-down|ARRB1-down JUN-down|ARRB1-down PDGFRA-down|ARRB1-down TGFB3-up|CCL11-up CXCL12-up|CCL11-up IGF1-up|CCL11-up JAK1-down|CCL11-up JUN-down|CCL11-up MMP1-up|CCL11-up MMP2-up|CCL13-up CXCL12-up|CCL13-up MMP1-up|CCL13-up MMP2-up|CXCR2-down CCND1-up|CXCL12-up CXCL2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL13-up MMP1-up|CXCL13-up MMP2-up|CXCL14-up IGF1-up|CXCL14-up JUN-down|CXCL14-up MMP1-up|CXCL14-up MMP2-up|CXCL2-down IGF1-up|CXCL2-down JUN-down|CXCL2-down MMP1-up|CXCL2-down MMP2-up|CXCL3-down JUN-down|CXCL3-down MMP2-up|CXCR2-down IGF1-up|CXCR2-down JUN-down|CXCR2-down MMP1-up|CXCR2-down MMP2-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 CXCL12-up_6387|ARRB1-down_408 EDNRB-down_1910|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 HHIP-down_64399|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JAK1-down_3716|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 PDGFRA-down_5156|ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 JAK1-down_3716|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP1-up_4312|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP1-up_4312|CCL13-up_6357 MMP2-up_4313|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL13-up_10563 MMP1-up_4312|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP1-up_4312|CXCL14-up_9547 MMP2-up_4313|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP1-up_4312|CXCR2-down_3579 MMP2-up_4313
hsa04062	hsa05202	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	ARRB1-down FLT1-down|ARRB1-down IGF1-up|CCL11-up FLT1-down|CCL11-up IGF1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up PLAU-up|CXCL12-up PROM1-up|CXCL12-up ZBTB16-down|CXCL14-up IGF1-up|CXCL14-up NFKBIZ-down|CXCL2-down IGF1-up|CXCL2-down IL1R2-down|CXCL2-down PLAU-up|CXCL3-down PLAU-up|CXCR2-down FLT1-down|CXCR2-down IGF1-up|CXCR2-down IL1R2-down|CXCR2-down PROM1-up	ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 IGF1-up_3479|CCL11-up_6356 FLT1-down_2321|CCL11-up_6356 IGF1-up_3479|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 PROM1-up_8842|CXCL12-up_6387 ZBTB16-down_7704|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 NFKBIZ-down_64332|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IL1R2-down_7850|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 IL1R2-down_7850|CXCR2-down_3579 PROM1-up_8842
hsa04062	hsa05205	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	ARRB1-down CCND1-up|ARRB1-down FLNC-up|ARRB1-down FZD5-down|ARRB1-down IGF1-up|CCL11-up HBEGF-down|CCL11-up IGF1-up|CCL11-up MMP2-up|CCL13-up MMP2-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up HBEGF-down|CXCL12-up IGF1-up|CXCL12-up MMP2-up|CXCL12-up PLAU-up|CXCL12-up THBS1-down|CXCL13-up MMP2-up|CXCL14-up HBEGF-down|CXCL14-up IGF1-up|CXCL14-up MMP2-up|CXCL14-up THBS1-down|CXCL2-down IGF1-up|CXCL2-down MMP2-up|CXCL2-down PLAU-up|CXCL3-down HBEGF-down|CXCL3-down MMP2-up|CXCL3-down PLAU-up|CXCR2-down IGF1-up|CXCR2-down MMP2-up|CXCR2-down THBS1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FLNC-up_2318|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 IGF1-up_3479|CCL11-up_6356 HBEGF-down_1839|CCL11-up_6356 IGF1-up_3479|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 MMP2-up_4313|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 THBS1-down_7057|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 HBEGF-down_1839|CXCL14-up_9547 IGF1-up_3479|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 THBS1-down_7057|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 MMP2-up_4313|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 THBS1-down_7057
hsa04062	hsa05206	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.003	ARRB1-down CCND1-up|ARRB1-down PDGFRA-down|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|CXCL12-up HMOX1-down|CXCL12-up MCL1-down|CXCL12-up MMP16-up|CXCL12-up PDGFRA-down|CXCL12-up PLAU-up|CXCL12-up SERPINB5-up|CXCL12-up SOX4-up|CXCL12-up THBS1-down|CXCL12-up TNC-up|CXCL13-up MCL1-down|CXCL14-up SERPINB5-up|CXCL14-up THBS1-down|CXCL14-up TNC-up|CXCL2-down CYP24A1-up|CXCL2-down IRS2-down|CXCL2-down PLAU-up|CXCL3-down PLAU-up|CXCR2-down CYP24A1-up|CXCR2-down HMOX1-down|CXCR2-down MCL1-down|CXCR2-down THBS1-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 PDGFRA-down_5156|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MMP16-up_4325|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SOX4-up_6659|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 TNC-up_3371|CXCL13-up_10563 MCL1-down_4170|CXCL14-up_9547 SERPINB5-up_5268|CXCL14-up_9547 THBS1-down_7057|CXCL14-up_9547 TNC-up_3371|CXCL2-down_2920 CYP24A1-up_1591|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 PLAU-up_5328|CXCR2-down_3579 CYP24A1-up_1591|CXCR2-down_3579 HMOX1-down_3162|CXCR2-down_3579 MCL1-down_4170|CXCR2-down_3579 THBS1-down_7057
hsa04062	hsa05219	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	ARRB1-down CCND1-up|CCL11-up HBEGF-down|CCL11-up MMP1-up|CCL11-up MMP2-up|CCL13-up MMP1-up|CCL13-up MMP2-up|CXCL12-up CCND1-up|CXCR2-down CCND1-up|CXCL12-up HBEGF-down|CXCL12-up MMP1-up|CXCL12-up MMP2-up|CXCL12-up THBS1-down|CXCL13-up MMP1-up|CXCL13-up MMP2-up|CXCL14-up HBEGF-down|CXCL14-up MMP1-up|CXCL14-up MMP2-up|CXCL14-up THBS1-down|CXCL2-down MMP1-up|CXCL2-down MMP2-up|CXCL3-down HBEGF-down|CXCL3-down MMP2-up|CXCR2-down MMP1-up|CXCR2-down MMP2-up|CXCR2-down THBS1-down	ARRB1-down_408 CCND1-up_595|CCL11-up_6356 HBEGF-down_1839|CCL11-up_6356 MMP1-up_4312|CCL11-up_6356 MMP2-up_4313|CCL13-up_6357 MMP1-up_4312|CCL13-up_6357 MMP2-up_4313|CXCL12-up_6387 CCND1-up_595|CXCR2-down_3579 CCND1-up_595|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 MMP1-up_4312|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 THBS1-down_7057|CXCL13-up_10563 MMP1-up_4312|CXCL13-up_10563 MMP2-up_4313|CXCL14-up_9547 HBEGF-down_1839|CXCL14-up_9547 MMP1-up_4312|CXCL14-up_9547 MMP2-up_4313|CXCL14-up_9547 THBS1-down_7057|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 MMP2-up_4313|CXCR2-down_3579 MMP1-up_4312|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 THBS1-down_7057
hsa04062	hsa05323	Chemokine signaling pathway - Homo sapiens (human)	ARRB1,CXCL2,CXCL3,CXCR2,CCL11,CCL13,CXCL12,CXCL13,CXCL14	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	ARRB1-down CXCL12-up|ARRB1-down FLT1-down|ARRB1-down JUN-down|ARRB1-down TGFB3-up|CCL11-up CXCL12-up|CCL11-up FLT1-down|CCL11-up JUN-down|CCL11-up MMP1-up|CCL13-up CXCL12-up|CCL13-up MMP1-up|CXCL14-up CTSK-up|CXCL12-up CXCL2-down|CXCL12-up CXCL3-down|CXCL12-up CXCR2-down|CXCL13-up MMP1-up|CXCL14-up JUN-down|CXCL14-up MMP1-up|CXCL2-down JUN-down|CXCL2-down MMP1-up|CXCL3-down JUN-down|CXCR2-down FLT1-down|CXCR2-down JUN-down|CXCR2-down MMP1-up	ARRB1-down_408 CXCL12-up_6387|ARRB1-down_408 FLT1-down_2321|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 TGFB3-up_7043|CCL11-up_6356 CXCL12-up_6387|CCL11-up_6356 FLT1-down_2321|CCL11-up_6356 JUN-down_3725|CCL11-up_6356 MMP1-up_4312|CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP1-up_4312|CXCL14-up_9547 CTSK-up_1513|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 CXCR2-down_3579|CXCL13-up_10563 MMP1-up_4312|CXCL14-up_9547 JUN-down_3725|CXCL14-up_9547 MMP1-up_4312|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|CXCL3-down_2921 JUN-down_3725|CXCR2-down_3579 FLT1-down_2321|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP1-up_4312
hsa04064	hsa04068	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	0.002	CXCL12-up CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|PLAU-up CCND2-up|CXCL12-up IGF1-up|CXCL12-up S1PR1-down|CXCL12-up SOD2-down|CXCL12-up TGFB3-up|CXCL2-down GADD45B-down|CXCL2-down IGF1-up|CXCL2-down IRS2-down|CXCL2-down S1PR1-down|CXCL2-down SOD2-down|VCAM1-up IGF1-up|PLAU-up TGFB3-up|VCAM1-up S1PR1-down|VCAM1-up TGFB3-up	CXCL12-up_6387 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 S1PR1-down_1901|CXCL12-up_6387 SOD2-down_6648|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 GADD45B-down_4616|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 S1PR1-down_1901|CXCL2-down_2920 SOD2-down_6648|VCAM1-up_7412 IGF1-up_3479|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 S1PR1-down_1901|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa04080	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	0	CXCL12-up APLNR-up|CXCL2-down APLNR-up|VCAM1-up APLNR-up|CXCL12-up EDNRB-down|CXCL12-up FPR1-down|CXCL12-up FPR2-down|CXCL12-up GABBR2-up|CXCL12-up S1PR1-down|CXCL12-up VIPR1-down|CXCL2-down FPR1-down|CXCL2-down FPR2-down|CXCL2-down S1PR1-down|VCAM1-up EDNRB-down|VCAM1-up FPR2-down|PLAU-up PRSS1-up|PLAU-up VIPR1-down|VCAM1-up S1PR1-down	CXCL12-up_6387 APLNR-up_187|CXCL2-down_2920 APLNR-up_187|VCAM1-up_7412 APLNR-up_187|CXCL12-up_6387 EDNRB-down_1910|CXCL12-up_6387 FPR1-down_2357|CXCL12-up_6387 FPR2-down_2358|CXCL12-up_6387 GABBR2-up_9568|CXCL12-up_6387 S1PR1-down_1901|CXCL12-up_6387 VIPR1-down_7433|CXCL2-down_2920 FPR1-down_2357|CXCL2-down_2920 FPR2-down_2358|CXCL2-down_2920 S1PR1-down_1901|VCAM1-up_7412 EDNRB-down_1910|VCAM1-up_7412 FPR2-down_2358|PLAU-up_5328 PRSS1-up_5644|PLAU-up_5328 VIPR1-down_7433|VCAM1-up_7412 S1PR1-down_1901
hsa04064	hsa04115	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	0.003	CXCL12-up CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|PLAU-up CCND2-up|CXCL12-up IGF1-up|CXCL12-up SERPINB5-up|CXCL12-up SERPINE1-down|CXCL12-up THBS1-down|CXCL2-down GADD45B-down|CXCL2-down IGF1-up|VCAM1-up IGF1-up|PLAU-up SERPINB5-up|PLAU-up SERPINE1-down|PLAU-up THBS1-down|VCAM1-up SERPINE1-down|VCAM1-up THBS1-down	CXCL12-up_6387 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 THBS1-down_7057|CXCL2-down_2920 GADD45B-down_4616|CXCL2-down_2920 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|PLAU-up_5328 SERPINB5-up_5268|PLAU-up_5328 SERPINE1-down_5054|PLAU-up_5328 THBS1-down_7057|VCAM1-up_7412 SERPINE1-down_5054|VCAM1-up_7412 THBS1-down_7057
hsa04064	hsa04144	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	0	CXCL12-up ARRB1-down|CXCL2-down ARRB1-down|CCL13-up CXCR2-down|CXCL12-up CXCR2-down|CXCL12-up DNM1-up|CXCL12-up FLT1-down|CXCL12-up LDLR-down|CXCL12-up PDGFRA-down|CXCL12-up TGFB3-up|CXCL2-down CXCR2-down|CXCL2-down HSPA1A-down|CXCL2-down LDLR-down|GADD45B-down CXCR2-down|VCAM1-up CXCR2-down|VCAM1-up DNM1-up|PLAU-up FLT1-down|VCAM1-up FLT1-down|VCAM1-up LDLR-down|PLAU-up PDGFRA-down|VCAM1-up PDGFRA-down|PLAU-up TGFB3-up|VCAM1-up TGFB3-up	CXCL12-up_6387 ARRB1-down_408|CXCL2-down_2920 ARRB1-down_408|CCL13-up_6357 CXCR2-down_3579|CXCL12-up_6387 CXCR2-down_3579|CXCL12-up_6387 DNM1-up_1759|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 LDLR-down_3949|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 CXCR2-down_3579|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 LDLR-down_3949|GADD45B-down_4616 CXCR2-down_3579|VCAM1-up_7412 CXCR2-down_3579|VCAM1-up_7412 DNM1-up_1759|PLAU-up_5328 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|VCAM1-up_7412 LDLR-down_3949|PLAU-up_5328 PDGFRA-down_5156|VCAM1-up_7412 PDGFRA-down_5156|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa04151	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0	CCL13-up SPP1-up|CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|PLAU-up CCND2-up|CXCL12-up COL1A1-up|CXCL2-down COL1A1-up|PLAU-up COL1A1-up|VCAM1-up COL1A1-up|CXCL12-up COL1A2-up|PLAU-up COL1A2-up|PLAU-up COL6A3-up|CXCL12-up COMP-up|CXCL12-up CSF3R-down|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up JAK1-down|CXCL12-up MCL1-down|CXCL12-up MYB-up|CXCL12-up PDGFRA-down|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL2-down IGF1-up|CXCL2-down MYB-up|CXCL2-down SPP1-up|PLAU-up FIGF-down|VCAM1-up FIGF-down|PLAU-up FLT1-down|VCAM1-up FLT1-down|GADD45B-down JAK1-down|GADD45B-down MCL1-down|GADD45B-down MYB-up|GADD45B-down THBS1-down|VCAM1-up IGF1-up|PLAU-up ITGB4-up|VCAM1-up ITGB4-up|PLAU-up JAK1-down|VCAM1-up JAK1-down|PLAU-up LAMA3-down|VCAM1-up LAMA3-down|VCAM1-up MCL1-down|VCAM1-up MYB-up|PLAU-up PDGFRA-down|VCAM1-up PDGFRA-down|PLAU-up SPP1-up|PLAU-up THBS1-down|PLAU-up THBS2-up|PLAU-up TNC-up|VCAM1-up SPP1-up|VCAM1-up THBS1-down|VCAM1-up THBS2-up|VCAM1-up TNC-up	CCL13-up_6357 SPP1-up_6696|CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|PLAU-up_5328 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|PLAU-up_5328 COL1A2-up_1278|PLAU-up_5328 COL6A3-up_1293|CXCL12-up_6387 COMP-up_1311|CXCL12-up_6387 CSF3R-down_1441|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 MYB-up_4602|CXCL2-down_2920 SPP1-up_6696|PLAU-up_5328 FIGF-down_2277|VCAM1-up_7412 FIGF-down_2277|PLAU-up_5328 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 MYB-up_4602|GADD45B-down_4616 THBS1-down_7057|VCAM1-up_7412 IGF1-up_3479|PLAU-up_5328 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|PLAU-up_5328 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|VCAM1-up_7412 MCL1-down_4170|VCAM1-up_7412 MYB-up_4602|PLAU-up_5328 PDGFRA-down_5156|VCAM1-up_7412 PDGFRA-down_5156|PLAU-up_5328 SPP1-up_6696|PLAU-up_5328 THBS1-down_7057|PLAU-up_5328 THBS2-up_7058|PLAU-up_5328 TNC-up_3371|VCAM1-up_7412 SPP1-up_6696|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 THBS2-up_7058|VCAM1-up_7412 TNC-up_3371
hsa04064	hsa04152	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	0.006	CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up HMGCR-down|CXCL12-up IGF1-up|CXCL2-down IGF1-up|CXCL2-down IRS2-down|CXCL2-down SCD-down|VCAM1-up FASN-down|PLAU-up HMGCR-down|VCAM1-up HMGCR-down|VCAM1-up IGF1-up	CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 HMGCR-down_3156|CXCL12-up_6387 IGF1-up_3479|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 SCD-down_6319|VCAM1-up_7412 FASN-down_2194|PLAU-up_5328 HMGCR-down_3156|VCAM1-up_7412 HMGCR-down_3156|VCAM1-up_7412 IGF1-up_3479
hsa04064	hsa04310	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	CCL13-up MMP7-up|CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|PLAU-up CCND2-up|CXCL12-up JUN-down|CXCL12-up MMP7-up|CXCL12-up SERPINF1-up|CXCL12-up SFRP2-up|CXCL2-down JUN-down|CXCL2-down MMP7-up|GADD45B-down JUN-down|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up MMP7-up|VCAM1-up MMP7-up|PLAU-up SERPINF1-up|VCAM1-up SERPINF1-up	CCL13-up_6357 MMP7-up_4316|CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP7-up_4316|CXCL12-up_6387 SERPINF1-up_5176|CXCL12-up_6387 SFRP2-up_6423|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP7-up_4316|GADD45B-down_4616 JUN-down_3725|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 MMP7-up_4316|VCAM1-up_7412 MMP7-up_4316|PLAU-up_5328 SERPINF1-up_5176|VCAM1-up_7412 SERPINF1-up_5176
hsa04064	hsa04350	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0.009	CXCL12-up ID1-down|CXCL12-up TGFB3-up|CXCL12-up THBS1-down|GADD45B-down THBS1-down|PLAU-up ID1-down|PLAU-up TGFB3-up|PLAU-up THBS1-down|VCAM1-up TGFB3-up|VCAM1-up THBS1-down	CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 THBS1-down_7057|GADD45B-down_4616 THBS1-down_7057|PLAU-up_5328 ID1-down_3397|PLAU-up_5328 TGFB3-up_7043|PLAU-up_5328 THBS1-down_7057|VCAM1-up_7412 TGFB3-up_7043|VCAM1-up_7412 THBS1-down_7057
hsa04064	hsa04380	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0	CXCL12-up CTSK-up|VCAM1-up CTSK-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL2-down JUN-down|CXCL2-down SOCS3-down|VCAM1-up FHL2-up|PLAU-up FOSL2-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|PLAU-up JAK1-down|VCAM1-up JAK1-down|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up SOCS3-down|VCAM1-up SOCS3-down	CXCL12-up_6387 CTSK-up_1513|VCAM1-up_7412 CTSK-up_1513|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|VCAM1-up_7412 FHL2-up_2274|PLAU-up_5328 FOSL2-down_2355|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04064	hsa04390	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.002	CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|PLAU-up CCND2-up|CXCL12-up ID1-down|CXCL12-up SERPINE1-down|CXCL12-up SOX2-up|CXCL12-up TGFB3-up|GADD45B-down SERPINE1-down|PLAU-up ID1-down|PLAU-up SERPINE1-down|PLAU-up TGFB3-up|VCAM1-up SERPINE1-down|VCAM1-up TGFB3-up	CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 SOX2-up_6657|CXCL12-up_6387 TGFB3-up_7043|GADD45B-down_4616 SERPINE1-down_5054|PLAU-up_5328 ID1-down_3397|PLAU-up_5328 SERPINE1-down_5054|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 SERPINE1-down_5054|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa04510	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCL13-up SPP1-up|CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|PLAU-up CCND2-up|CXCL12-up COL1A1-up|CXCL2-down COL1A1-up|PLAU-up COL1A1-up|VCAM1-up COL1A1-up|CXCL12-up COL1A2-up|PLAU-up COL1A2-up|PLAU-up COL6A3-up|CXCL12-up COMP-up|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up JUN-down|CXCL12-up PDGFRA-down|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL2-down IGF1-up|CXCL2-down JUN-down|CXCL2-down SPP1-up|PLAU-up FIGF-down|VCAM1-up FIGF-down|VCAM1-up FLNC-up|PLAU-up FLT1-down|VCAM1-up FLT1-down|GADD45B-down JUN-down|GADD45B-down THBS1-down|VCAM1-up IGF1-up|PLAU-up ITGB4-up|VCAM1-up ITGB4-up|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up LAMA3-down|VCAM1-up LAMA3-down|PLAU-up PDGFRA-down|VCAM1-up PDGFRA-down|PLAU-up SPP1-up|PLAU-up THBS1-down|PLAU-up THBS2-up|PLAU-up TNC-up|VCAM1-up SPP1-up|VCAM1-up THBS1-down|VCAM1-up THBS2-up|VCAM1-up TNC-up	CCL13-up_6357 SPP1-up_6696|CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|PLAU-up_5328 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|PLAU-up_5328 COL1A2-up_1278|PLAU-up_5328 COL6A3-up_1293|CXCL12-up_6387 COMP-up_1311|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SPP1-up_6696|PLAU-up_5328 FIGF-down_2277|VCAM1-up_7412 FIGF-down_2277|VCAM1-up_7412 FLNC-up_2318|PLAU-up_5328 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 THBS1-down_7057|VCAM1-up_7412 IGF1-up_3479|PLAU-up_5328 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|PLAU-up_5328 PDGFRA-down_5156|VCAM1-up_7412 PDGFRA-down_5156|PLAU-up_5328 SPP1-up_6696|PLAU-up_5328 THBS1-down_7057|PLAU-up_5328 THBS2-up_7058|PLAU-up_5328 TNC-up_3371|VCAM1-up_7412 SPP1-up_6696|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 THBS2-up_7058|VCAM1-up_7412 TNC-up_3371
hsa04064	hsa04512	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCL13-up SPP1-up|CXCL12-up COL1A1-up|CXCL2-down COL1A1-up|PLAU-up COL1A1-up|VCAM1-up COL1A1-up|CXCL12-up COL1A2-up|PLAU-up COL1A2-up|PLAU-up COL6A3-up|CXCL12-up COMP-up|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|CXCL2-down SPP1-up|GADD45B-down THBS1-down|PLAU-up ITGB4-up|VCAM1-up ITGB4-up|PLAU-up LAMA3-down|VCAM1-up LAMA3-down|PLAU-up SPP1-up|PLAU-up THBS1-down|PLAU-up THBS2-up|PLAU-up TNC-up|VCAM1-up SPP1-up|VCAM1-up THBS1-down|VCAM1-up THBS2-up|VCAM1-up TNC-up	CCL13-up_6357 SPP1-up_6696|CXCL12-up_6387 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|PLAU-up_5328 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|PLAU-up_5328 COL1A2-up_1278|PLAU-up_5328 COL6A3-up_1293|CXCL12-up_6387 COMP-up_1311|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|CXCL2-down_2920 SPP1-up_6696|GADD45B-down_4616 THBS1-down_7057|PLAU-up_5328 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|PLAU-up_5328 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|PLAU-up_5328 SPP1-up_6696|PLAU-up_5328 THBS1-down_7057|PLAU-up_5328 THBS2-up_7058|PLAU-up_5328 TNC-up_3371|VCAM1-up_7412 SPP1-up_6696|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 THBS2-up_7058|VCAM1-up_7412 TNC-up_3371
hsa04064	hsa04514	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CCL13-up NCAM1-up|CCL13-up VCAM1-up|CXCL12-up CD274-down|CXCL12-up CDH2-up|PLAU-up CDH2-up|PLAU-up CDH3-up|GADD45B-down CLDN1-up|PLAU-up CLDN1-up|CXCL12-up CLDN5-down|CXCL12-up NCAM1-up|CXCL12-up SELL-down|CXCL12-up VCAM1-up|CXCL12-up VTCN1-up|CXCL2-down SELL-down|CXCL2-down VCAM1-up|GADD45B-down VCAM1-up|PLAU-up VCAM1-up	CCL13-up_6357 NCAM1-up_4684|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CD274-down_29126|CXCL12-up_6387 CDH2-up_1000|PLAU-up_5328 CDH2-up_1000|PLAU-up_5328 CDH3-up_1001|GADD45B-down_4616 CLDN1-up_9076|PLAU-up_5328 CLDN1-up_9076|CXCL12-up_6387 CLDN5-down_7122|CXCL12-up_6387 NCAM1-up_4684|CXCL12-up_6387 SELL-down_6402|CXCL12-up_6387 VCAM1-up_7412|CXCL12-up_6387 VTCN1-up_79679|CXCL2-down_2920 SELL-down_6402|CXCL2-down_2920 VCAM1-up_7412|GADD45B-down_4616 VCAM1-up_7412|PLAU-up_5328 VCAM1-up_7412
hsa04064	hsa04550	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0	CXCL12-up ID1-down|CXCL12-up IGF1-up|CXCL12-up JAK1-down|CXCL12-up LIFR-down|CXCL12-up SOX2-up|CXCL2-down IGF1-up|GADD45B-down JAK1-down|PLAU-up ID1-down|VCAM1-up IGF1-up|PLAU-up JAK1-down|VCAM1-up JAK1-down|VCAM1-up LIFR-down	CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 SOX2-up_6657|CXCL2-down_2920 IGF1-up_3479|GADD45B-down_4616 JAK1-down_3716|PLAU-up_5328 ID1-down_3397|VCAM1-up_7412 IGF1-up_3479|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|VCAM1-up_7412 LIFR-down_3977
hsa04064	hsa04610	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.014	CXCL12-up F3-down|CXCL12-up PLAU-up|CXCL12-up SERPINE1-down|CXCL12-up TFPI-down|CXCL2-down PLAU-up|VCAM1-up F3-down|GADD45B-down PLAU-up|GADD45B-down SERPINE1-down|VCAM1-up SERPINE1-down|VCAM1-up TFPI-down	CXCL12-up_6387 F3-down_2152|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 TFPI-down_7035|CXCL2-down_2920 PLAU-up_5328|VCAM1-up_7412 F3-down_2152|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 SERPINE1-down_5054|VCAM1-up_7412 SERPINE1-down_5054|VCAM1-up_7412 TFPI-down_7035
hsa04064	hsa04630	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0	CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|PLAU-up CCND2-up|CXCL12-up CSF3R-down|CXCL12-up JAK1-down|CXCL12-up LIFR-down|CXCL12-up MCL1-down|CXCL12-up SOCS3-down|CXCL2-down SOCS3-down|GADD45B-down JAK1-down|GADD45B-down MCL1-down|GADD45B-down SOCS3-down|PLAU-up JAK1-down|VCAM1-up JAK1-down|VCAM1-up LIFR-down|VCAM1-up MCL1-down|PLAU-up SOCS3-down|VCAM1-up SOCS3-down	CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 CSF3R-down_1441|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 SOCS3-down_9021|CXCL2-down_2920 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|VCAM1-up_7412 LIFR-down_3977|VCAM1-up_7412 MCL1-down_4170|PLAU-up_5328 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04064	hsa04668	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.001	CCL13-up CXCL3-down|CCL13-up VCAM1-up|CXCL12-up CXCL3-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL12-up VCAM1-up|PLAU-up CXCL3-down|GADD45B-down IL18R1-down|GADD45B-down JUN-down|GADD45B-down MAP3K8-down|GADD45B-down SOCS3-down|GADD45B-down VCAM1-up|PLAU-up JUN-down|PLAU-up MAP3K8-down|PLAU-up SOCS3-down|PLAU-up VCAM1-up	CCL13-up_6357 CXCL3-down_2921|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CXCL3-down_2921|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL12-up_6387 VCAM1-up_7412|PLAU-up_5328 CXCL3-down_2921|GADD45B-down_4616 IL18R1-down_8809|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MAP3K8-down_1326|GADD45B-down_4616 SOCS3-down_9021|GADD45B-down_4616 VCAM1-up_7412|PLAU-up_5328 JUN-down_3725|PLAU-up_5328 MAP3K8-down_1326|PLAU-up_5328 SOCS3-down_9021|PLAU-up_5328 VCAM1-up_7412
hsa04064	hsa04670	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CCL13-up CXCL12-up|CCL13-up MMP2-up|CCL13-up VCAM1-up|GADD45B-down CLDN1-up|PLAU-up CLDN1-up|CXCL12-up CXCL2-down|CXCL12-up GADD45B-down|CXCL2-down MMP2-up|CXCL2-down VCAM1-up|GADD45B-down MMP2-up|GADD45B-down VCAM1-up|PLAU-up MMP2-up|PLAU-up VCAM1-up	CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP2-up_4313|CCL13-up_6357 VCAM1-up_7412|GADD45B-down_4616 CLDN1-up_9076|PLAU-up_5328 CLDN1-up_9076|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 GADD45B-down_4616|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 VCAM1-up_7412|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 VCAM1-up_7412|PLAU-up_5328 MMP2-up_4313|PLAU-up_5328 VCAM1-up_7412
hsa04064	hsa04915	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	CCL13-up MMP2-up|CXCL12-up GABBR2-up|CXCL12-up HBEGF-down|CXCL12-up JUN-down|CXCL12-up MMP2-up|CXCL2-down HSPA1A-down|CXCL2-down JUN-down|CXCL2-down KCNJ5-up|CXCL2-down MMP2-up|GADD45B-down HBEGF-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|PLAU-up HBEGF-down|VCAM1-up HBEGF-down|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up MMP2-up|VCAM1-up MMP2-up	CCL13-up_6357 MMP2-up_4313|CXCL12-up_6387 GABBR2-up_9568|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP2-up_4313|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 KCNJ5-up_3762|CXCL2-down_2920 MMP2-up_4313|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|PLAU-up_5328 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313
hsa04064	hsa04933	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CCL13-up MMP2-up|CCL13-up VCAM1-up|CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|CXCL12-up COL1A1-up|CXCL2-down COL1A1-up|PLAU-up COL1A1-up|CXCL12-up COL1A2-up|PLAU-up COL1A2-up|CXCL12-up COL3A1-up|PLAU-up COL3A1-up|CXCL12-up F3-down|CXCL12-up FIGF-down|CXCL12-up JUN-down|CXCL12-up MMP2-up|CXCL12-up SERPINE1-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|CXCL2-down JUN-down|CXCL2-down MMP2-up|CXCL2-down VCAM1-up|PLAU-up F3-down|PLAU-up FIGF-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|GADD45B-down SERPINE1-down|GADD45B-down VCAM1-up|PLAU-up JUN-down|PLAU-up MMP2-up|PLAU-up SERPINE1-down|PLAU-up TGFB3-up|PLAU-up VCAM1-up	CCL13-up_6357 MMP2-up_4313|CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|CXCL12-up_6387 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|PLAU-up_5328 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|PLAU-up_5328 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|PLAU-up_5328 COL3A1-up_1281|CXCL12-up_6387 F3-down_2152|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 VCAM1-up_7412|PLAU-up_5328 F3-down_2152|PLAU-up_5328 FIGF-down_2277|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 SERPINE1-down_5054|GADD45B-down_4616 VCAM1-up_7412|PLAU-up_5328 JUN-down_3725|PLAU-up_5328 MMP2-up_4313|PLAU-up_5328 SERPINE1-down_5054|PLAU-up_5328 TGFB3-up_7043|PLAU-up_5328 VCAM1-up_7412
hsa04064	hsa04974	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	PLAU-up COL15A1-up|CXCL12-up COL18A1-up|PLAU-up COL18A1-up|VCAM1-up COL18A1-up|CXCL12-up COL1A1-up|CXCL2-down COL1A1-up|PLAU-up COL1A1-up|VCAM1-up COL1A1-up|CXCL12-up COL1A2-up|PLAU-up COL1A2-up|CXCL12-up COL3A1-up|PLAU-up COL3A1-up|PLAU-up COL5A1-up|PLAU-up COL5A2-up|PLAU-up COL6A3-up|CXCL12-up MME-down|PLAU-up MME-down|VCAM1-up MME-down|PLAU-up PRSS1-up	PLAU-up_5328 COL15A1-up_1306|CXCL12-up_6387 COL18A1-up_80781|PLAU-up_5328 COL18A1-up_80781|VCAM1-up_7412 COL18A1-up_80781|CXCL12-up_6387 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|PLAU-up_5328 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|PLAU-up_5328 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|PLAU-up_5328 COL3A1-up_1281|PLAU-up_5328 COL5A1-up_1289|PLAU-up_5328 COL5A2-up_1290|PLAU-up_5328 COL6A3-up_1293|CXCL12-up_6387 MME-down_4311|PLAU-up_5328 MME-down_4311|VCAM1-up_7412 MME-down_4311|PLAU-up_5328 PRSS1-up_5644
hsa04064	hsa04978	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.006	CXCL12-up HMOX1-down|CXCL12-up TF-up|GADD45B-down HMOX1-down|GADD45B-down MT1X-down|PLAU-up HMOX1-down|VCAM1-up HMOX1-down|VCAM1-up MT2A-down|PLAU-up TF-up|VCAM1-up TF-up	CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 TF-up_7018|GADD45B-down_4616 HMOX1-down_3162|GADD45B-down_4616 MT1X-down_4501|PLAU-up_5328 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|VCAM1-up_7412 MT2A-down_4502|PLAU-up_5328 TF-up_7018|VCAM1-up_7412 TF-up_7018
hsa04064	hsa05145	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0	CXCL12-up JAK1-down|CXCL12-up LDLR-down|CXCL12-up TGFB3-up|CXCL2-down HSPA1A-down|CXCL2-down LDLR-down|GADD45B-down JAK1-down|PLAU-up JAK1-down|VCAM1-up JAK1-down|PLAU-up LAMA3-down|VCAM1-up LAMA3-down|VCAM1-up LDLR-down|PLAU-up TGFB3-up|VCAM1-up TGFB3-up	CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LDLR-down_3949|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 LDLR-down_3949|GADD45B-down_4616 JAK1-down_3716|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|PLAU-up_5328 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|VCAM1-up_7412 LDLR-down_3949|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa05146	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CXCL12-up COL1A1-up|CXCL2-down COL1A1-up|PLAU-up COL1A1-up|VCAM1-up COL1A1-up|CXCL12-up COL1A2-up|PLAU-up COL1A2-up|CXCL12-up COL3A1-up|PLAU-up COL3A1-up|CXCL12-up TGFB3-up|CXCL2-down IL1R2-down|GADD45B-down IL1R2-down|PLAU-up LAMA3-down|VCAM1-up LAMA3-down|PLAU-up SERPINB3-up|PLAU-up TGFB3-up|VCAM1-up TGFB3-up	CXCL12-up_6387 COL1A1-up_1277|CXCL2-down_2920 COL1A1-up_1277|PLAU-up_5328 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|PLAU-up_5328 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|PLAU-up_5328 COL3A1-up_1281|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 IL1R2-down_7850|GADD45B-down_4616 IL1R2-down_7850|PLAU-up_5328 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|PLAU-up_5328 SERPINB3-up_6317|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa05152	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0	CXCL12-up CD74-up|VCAM1-up CD74-up|GADD45B-down CLEC4E-down|PLAU-up CLEC4E-down|CXCL12-up JAK1-down|CXCL12-up TGFB3-up|GADD45B-down JAK1-down|PLAU-up JAK1-down|VCAM1-up JAK1-down|PLAU-up TGFB3-up|VCAM1-up TGFB3-up	CXCL12-up_6387 CD74-up_972|VCAM1-up_7412 CD74-up_972|GADD45B-down_4616 CLEC4E-down_26253|PLAU-up_5328 CLEC4E-down_26253|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 TGFB3-up_7043|GADD45B-down_4616 JAK1-down_3716|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa05160	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0	GADD45B-down CLDN1-up|PLAU-up CLDN1-up|CXCL12-up CLDN5-down|VCAM1-up CLDN5-down|CXCL12-up JAK1-down|CXCL12-up LDLR-down|CXCL12-up SOCS3-down|CXCL2-down LDLR-down|CXCL2-down SOCS3-down|GADD45B-down JAK1-down|GADD45B-down SOCS3-down|PLAU-up JAK1-down|VCAM1-up JAK1-down|VCAM1-up LDLR-down|PLAU-up SOCS3-down|VCAM1-up SOCS3-down	GADD45B-down_4616 CLDN1-up_9076|PLAU-up_5328 CLDN1-up_9076|CXCL12-up_6387 CLDN5-down_7122|VCAM1-up_7412 CLDN5-down_7122|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LDLR-down_3949|CXCL12-up_6387 SOCS3-down_9021|CXCL2-down_2920 LDLR-down_3949|CXCL2-down_2920 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|VCAM1-up_7412 LDLR-down_3949|PLAU-up_5328 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04064	hsa05164	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0	CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL2-down HSPA1A-down|CXCL2-down JUN-down|CXCL2-down SOCS3-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|PLAU-up JAK1-down|VCAM1-up JAK1-down|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up PRSS1-up|PLAU-up SOCS3-down|PLAU-up TMPRSS4-up|VCAM1-up SOCS3-down	CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 PRSS1-up_5644|PLAU-up_5328 SOCS3-down_9021|PLAU-up_5328 TMPRSS4-up_56649|VCAM1-up_7412 SOCS3-down_9021
hsa04064	hsa05166	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	CCL13-up VCAM1-up|CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|PLAU-up CCND2-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up MYB-up|CXCL12-up PDGFRA-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|CXCL2-down IL1R2-down|CXCL2-down JUN-down|CXCL2-down MYB-up|CXCL2-down VCAM1-up|GADD45B-down IL1R2-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down MYB-up|GADD45B-down VCAM1-up|PLAU-up JAK1-down|PLAU-up JUN-down|PLAU-up PDGFRA-down|PLAU-up TGFB3-up|PLAU-up VCAM1-up	CCL13-up_6357 VCAM1-up_7412|CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|PLAU-up_5328 CCND2-up_894|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|CXCL2-down_2920 IL1R2-down_7850|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MYB-up_4602|CXCL2-down_2920 VCAM1-up_7412|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MYB-up_4602|GADD45B-down_4616 VCAM1-up_7412|PLAU-up_5328 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|PLAU-up_5328 PDGFRA-down_5156|PLAU-up_5328 TGFB3-up_7043|PLAU-up_5328 VCAM1-up_7412
hsa04064	hsa05168	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	CXCL12-up CD74-up|VCAM1-up CD74-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|CXCL2-down JUN-down|CXCL2-down SOCS3-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|PLAU-up JAK1-down|VCAM1-up JAK1-down|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up SOCS3-down|VCAM1-up SOCS3-down	CXCL12-up_6387 CD74-up_972|VCAM1-up_7412 CD74-up_972|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04064	hsa05200	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.006	CCL13-up CXCL12-up|CCL13-up MMP1-up|CCL13-up MMP2-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CXCL2-down|CXCL12-up GADD45B-down|CXCL2-down IGF1-up|CXCL2-down JUN-down|CXCL2-down MMP1-up|CXCL2-down MMP2-up|GADD45B-down DAPK2-down|VCAM1-up EDNRB-down|PLAU-up FIGF-down|VCAM1-up FIGF-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|VCAM1-up IGF1-up|PLAU-up JAK1-down|VCAM1-up JAK1-down|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up LAMA3-down|VCAM1-up LAMA3-down|PLAU-up MMP1-up|VCAM1-up MMP1-up|PLAU-up MMP2-up|VCAM1-up MMP2-up|PLAU-up PDGFRA-down|VCAM1-up PDGFRA-down|PLAU-up TGFB3-up|VCAM1-up TGFB3-up	CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP1-up_4312|CCL13-up_6357 MMP2-up_4313|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 GADD45B-down_4616|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|GADD45B-down_4616 DAPK2-down_23604|VCAM1-up_7412 EDNRB-down_1910|PLAU-up_5328 FIGF-down_2277|VCAM1-up_7412 FIGF-down_2277|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|VCAM1-up_7412 IGF1-up_3479|PLAU-up_5328 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|PLAU-up_5328 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|PLAU-up_5328 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|PLAU-up_5328 PDGFRA-down_5156|VCAM1-up_7412 PDGFRA-down_5156|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa05202	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.006	CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up PLAU-up|CXCL12-up PROM1-up|CXCL12-up ZBTB16-down|CXCL2-down IGF1-up|CXCL2-down IL1R2-down|CXCL2-down PLAU-up|VCAM1-up FLT1-down|GADD45B-down IL1R2-down|GADD45B-down NFKBIZ-down|GADD45B-down PLAU-up|VCAM1-up IGF1-up|VCAM1-up PROM1-up	CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 PROM1-up_8842|CXCL12-up_6387 ZBTB16-down_7704|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IL1R2-down_7850|CXCL2-down_2920 PLAU-up_5328|VCAM1-up_7412 FLT1-down_2321|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 NFKBIZ-down_64332|GADD45B-down_4616 PLAU-up_5328|VCAM1-up_7412 IGF1-up_3479|VCAM1-up_7412 PROM1-up_8842
hsa04064	hsa05205	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.001	CCL13-up MMP2-up|CXCL12-up CCND1-up|GADD45B-down CCND1-up|VCAM1-up CCND1-up|CXCL12-up HBEGF-down|CXCL12-up IGF1-up|CXCL12-up MMP2-up|CXCL12-up PLAU-up|CXCL12-up THBS1-down|CXCL2-down IGF1-up|CXCL2-down MMP2-up|CXCL2-down PLAU-up|VCAM1-up FLNC-up|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down PLAU-up|GADD45B-down THBS1-down|VCAM1-up HBEGF-down|VCAM1-up IGF1-up|VCAM1-up MMP2-up|VCAM1-up THBS1-down	CCL13-up_6357 MMP2-up_4313|CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 THBS1-down_7057|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 PLAU-up_5328|VCAM1-up_7412 FLNC-up_2318|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|VCAM1-up_7412 HBEGF-down_1839|VCAM1-up_7412 IGF1-up_3479|VCAM1-up_7412 MMP2-up_4313|VCAM1-up_7412 THBS1-down_7057
hsa04064	hsa05206	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.001	CXCL12-up CCND1-up|GADD45B-down CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|CXCL2-down CCND2-up|GADD45B-down CCND2-up|CXCL12-up HMOX1-down|CXCL12-up MCL1-down|CXCL12-up MMP16-up|CXCL12-up PDGFRA-down|CXCL12-up PLAU-up|CXCL12-up SERPINB5-up|CXCL12-up SOX4-up|CXCL12-up THBS1-down|CXCL12-up TNC-up|CXCL2-down CYP24A1-up|CXCL2-down IRS2-down|CXCL2-down PLAU-up|GADD45B-down HMOX1-down|GADD45B-down MCL1-down|GADD45B-down PLAU-up|GADD45B-down THBS1-down|VCAM1-up HMOX1-down|VCAM1-up MCL1-down|VCAM1-up PDGFRA-down|VCAM1-up THBS1-down|VCAM1-up TNC-up	CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL2-down_2920 CCND2-up_894|GADD45B-down_4616 CCND2-up_894|CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MMP16-up_4325|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SOX4-up_6659|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 TNC-up_3371|CXCL2-down_2920 CYP24A1-up_1591|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 PLAU-up_5328|GADD45B-down_4616 HMOX1-down_3162|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|VCAM1-up_7412 HMOX1-down_3162|VCAM1-up_7412 MCL1-down_4170|VCAM1-up_7412 PDGFRA-down_5156|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 TNC-up_3371
hsa04064	hsa05219	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCL13-up MMP1-up|CCL13-up MMP2-up|CXCL12-up CCND1-up|GADD45B-down CCND1-up|PLAU-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up HBEGF-down|CXCL12-up MMP1-up|CXCL12-up MMP2-up|CXCL12-up THBS1-down|CXCL2-down MMP1-up|CXCL2-down MMP2-up|GADD45B-down DAPK2-down|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down THBS1-down|PLAU-up HBEGF-down|VCAM1-up HBEGF-down|PLAU-up MMP1-up|VCAM1-up MMP1-up|PLAU-up MMP2-up|VCAM1-up MMP2-up|PLAU-up THBS1-down|VCAM1-up THBS1-down	CCL13-up_6357 MMP1-up_4312|CCL13-up_6357 MMP2-up_4313|CXCL12-up_6387 CCND1-up_595|GADD45B-down_4616 CCND1-up_595|PLAU-up_5328 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 MMP1-up_4312|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 THBS1-down_7057|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|GADD45B-down_4616 DAPK2-down_23604|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 THBS1-down_7057|PLAU-up_5328 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|PLAU-up_5328 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|PLAU-up_5328 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|PLAU-up_5328 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04064	hsa05323	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.004	CCL13-up CXCL12-up|CCL13-up MMP1-up|VCAM1-up CTSK-up|CXCL12-up CXCL2-down|CXCL12-up GADD45B-down|CXCL2-down JUN-down|CXCL2-down MMP1-up|PLAU-up FLT1-down|VCAM1-up FLT1-down|GADD45B-down JUN-down|PLAU-up JUN-down|VCAM1-up JUN-down|PLAU-up MMP1-up|VCAM1-up MMP1-up|PLAU-up TGFB3-up|VCAM1-up TGFB3-up	CCL13-up_6357 CXCL12-up_6387|CCL13-up_6357 MMP1-up_4312|VCAM1-up_7412 CTSK-up_1513|CXCL12-up_6387 CXCL2-down_2920|CXCL12-up_6387 GADD45B-down_4616|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|PLAU-up_5328 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|GADD45B-down_4616 JUN-down_3725|PLAU-up_5328 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|PLAU-up_5328 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa05410	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.046	CXCL12-up IGF1-up|CXCL12-up TGFB3-up|CXCL2-down IGF1-up|VCAM1-up IGF1-up|PLAU-up ITGB4-up|VCAM1-up ITGB4-up|PLAU-up TGFB3-up|VCAM1-up TGFB3-up	CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|CXCL2-down_2920 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|PLAU-up_5328 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|PLAU-up_5328 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04064	hsa05412	NF-kappa B signaling pathway - Homo sapiens (human)	CXCL2,GADD45B,CCL13,CXCL12,PLAU,VCAM1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.041	CXCL12-up CDH2-up|PLAU-up CDH2-up|VCAM1-up CDH2-up|PLAU-up ITGB4-up|VCAM1-up ITGB4-up	CXCL12-up_6387 CDH2-up_1000|PLAU-up_5328 CDH2-up_1000|VCAM1-up_7412 CDH2-up_1000|PLAU-up_5328 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691
hsa04068	hsa04151	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0.036	CCND1-up GADD45B-down|CCND1-up IRS2-down|CCND2-up GADD45B-down|CCND2-up IRS2-down|TGFB3-up COL1A1-up|TGFB3-up COL1A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|TGFB3-up COMP-up|FBXO32-up IGF1-up|TGFB3-up FGF14-up|S1PR1-down FIGF-down|TGFB3-up FIGF-down|IRS2-down FLT1-down|S1PR1-down FLT1-down|TGFB3-up FLT1-down|GADD45B-down JAK1-down|GADD45B-down MCL1-down|GADD45B-down MYB-up|GADD45B-down THBS1-down|IGF1-up IRS2-down|IGF1-up SOD2-down|IRS2-down JAK1-down|IRS2-down MYB-up|IRS2-down PDGFRA-down|IRS2-down PRKAA2-up|IRS2-down SPP1-up|TGFB3-up ITGB8-up|S1PR1-down JAK1-down|S1PR1-down MCL1-down|SOD2-down MCL1-down|S1PR1-down PDGFRA-down|TGFB3-up PDGFRA-down|PRKAA2-up SOD2-down|S1PR1-down THBS1-down|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 IRS2-down_8660|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 IRS2-down_8660|TGFB3-up_7043 COL1A1-up_1277|TGFB3-up_7043 COL1A2-up_1278|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|TGFB3-up_7043 COMP-up_1311|FBXO32-up_114907 IGF1-up_3479|TGFB3-up_7043 FGF14-up_2259|S1PR1-down_1901 FIGF-down_2277|TGFB3-up_7043 FIGF-down_2277|IRS2-down_8660 FLT1-down_2321|S1PR1-down_1901 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 MYB-up_4602|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 SOD2-down_6648|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 MYB-up_4602|IRS2-down_8660 PDGFRA-down_5156|IRS2-down_8660 PRKAA2-up_5563|IRS2-down_8660 SPP1-up_6696|TGFB3-up_7043 ITGB8-up_3696|S1PR1-down_1901 JAK1-down_3716|S1PR1-down_1901 MCL1-down_4170|SOD2-down_6648 MCL1-down_4170|S1PR1-down_1901 PDGFRA-down_5156|TGFB3-up_7043 PDGFRA-down_5156|PRKAA2-up_5563 SOD2-down_6648|S1PR1-down_1901 THBS1-down_7057|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04068	hsa04310	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	CCND1-up GADD45B-down|CCND1-up IRS2-down|CCND2-up GADD45B-down|CCND2-up IRS2-down|FBXO32-up JUN-down|GADD45B-down JUN-down|IGF1-up JUN-down|IGF1-up MMP7-up|IGF1-up SERPINF1-up|IGF1-up SFRP2-up|IGF1-up SFRP4-up|IGF1-up TCF7L2-up|IRS2-down JUN-down|IRS2-down TCF7L2-up|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|TGFB3-up JUN-down|SOD2-down MMP7-up|SOD2-down SERPINF1-up|TGFB3-up SFRP2-up|TGFB3-up SFRP4-up|TGFB3-up TCF7L2-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 IRS2-down_8660|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 IRS2-down_8660|FBXO32-up_114907 JUN-down_3725|GADD45B-down_4616 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP7-up_4316|IGF1-up_3479 SERPINF1-up_5176|IGF1-up_3479 SFRP2-up_6423|IGF1-up_3479 SFRP4-up_6424|IGF1-up_3479 TCF7L2-up_6934|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 TCF7L2-up_6934|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|SOD2-down_6648 MMP7-up_4316|SOD2-down_6648 SERPINF1-up_5176|TGFB3-up_7043 SFRP2-up_6423|TGFB3-up_7043 SFRP4-up_6424|TGFB3-up_7043 TCF7L2-up_6934
hsa04068	hsa04350	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0.013	CCND1-up ID1-down|CCND1-up SMAD6-down|CCND1-up TGFB3-up|CCND1-up THBS1-down|CCND2-up SMAD6-down|CCND2-up TGFB3-up|CCND2-up THBS1-down|GADD45B-down THBS1-down|IGF1-up ID1-down|IGF1-up SMAD6-down|IGF1-up TGFB3-up|IGF1-up THBS1-down|S1PR1-down THBS1-down	CCND1-up_595 ID1-down_3397|CCND1-up_595 SMAD6-down_4091|CCND1-up_595 TGFB3-up_7043|CCND1-up_595 THBS1-down_7057|CCND2-up_894 SMAD6-down_4091|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 THBS1-down_7057|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 ID1-down_3397|IGF1-up_3479 SMAD6-down_4091|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 THBS1-down_7057|S1PR1-down_1901 THBS1-down_7057
hsa04068	hsa04380	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0	CCND1-up CTSK-up|CCND1-up FHL2-up|CCND1-up FOSL2-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up FOSL2-down|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up SOCS3-down|IGF1-up CTSK-up|SOD2-down CTSK-up|FBXO32-up FHL2-up|FBXO32-up JUN-down|FBXO32-up SOCS3-down|IGF1-up FHL2-up|S1PR1-down FHL2-up|IGF1-up FOSL2-down|TGFB3-up FOSL2-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|S1PR1-down JAK1-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|TGFB3-up JUN-down|SOD2-down SOCS3-down	CCND1-up_595 CTSK-up_1513|CCND1-up_595 FHL2-up_2274|CCND1-up_595 FOSL2-down_2355|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 FOSL2-down_2355|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|IGF1-up_3479 CTSK-up_1513|SOD2-down_6648 CTSK-up_1513|FBXO32-up_114907 FHL2-up_2274|FBXO32-up_114907 JUN-down_3725|FBXO32-up_114907 SOCS3-down_9021|IGF1-up_3479 FHL2-up_2274|S1PR1-down_1901 FHL2-up_2274|IGF1-up_3479 FOSL2-down_2355|TGFB3-up_7043 FOSL2-down_2355|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|S1PR1-down_1901 JAK1-down_3716|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|SOD2-down_6648 SOCS3-down_9021
hsa04068	hsa04512	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up ITGB4-up|CCND1-up LAMA3-down|CCND1-up SPP1-up|CCND1-up THBS1-down|CCND1-up THBS2-up|CCND1-up TNC-up|CCND2-up COL1A2-up|CCND2-up THBS1-down|CCND2-up TNC-up|IGF1-up COL1A1-up|TGFB3-up COL1A1-up|IGF1-up COL1A2-up|TGFB3-up COL1A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|IGF1-up COMP-up|TGFB3-up COMP-up|GADD45B-down THBS1-down|IGF1-up SPP1-up|IGF1-up THBS1-down|IGF1-up THBS2-up|IGF1-up TNC-up|IRS2-down SPP1-up|TGFB3-up ITGB8-up|S1PR1-down THBS1-down|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 SPP1-up_6696|CCND1-up_595 THBS1-down_7057|CCND1-up_595 THBS2-up_7058|CCND1-up_595 TNC-up_3371|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 THBS1-down_7057|CCND2-up_894 TNC-up_3371|IGF1-up_3479 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|IGF1-up_3479 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 SPP1-up_6696|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 THBS2-up_7058|IGF1-up_3479 TNC-up_3371|IRS2-down_8660 SPP1-up_6696|TGFB3-up_7043 ITGB8-up_3696|S1PR1-down_1901 THBS1-down_7057|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04068	hsa04514	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CCND1-up CD274-down|CCND1-up CDH2-up|CCND1-up CDH3-up|CCND1-up NCAM1-up|CCND1-up VCAM1-up|CCND2-up CDH2-up|CCND2-up NCAM1-up|IGF1-up CD274-down|IGF1-up CDH2-up|S1PR1-down CDH2-up|TGFB3-up CDH2-up|GADD45B-down CLDN1-up|IGF1-up CLDN5-down|GADD45B-down VCAM1-up|IGF1-up NCAM1-up|IGF1-up SELL-down|IGF1-up VCAM1-up|TGFB3-up ITGB8-up|TGFB3-up NCAM1-up|S1PR1-down SELL-down|S1PR1-down VCAM1-up|TGFB3-up VCAM1-up	CCND1-up_595 CD274-down_29126|CCND1-up_595 CDH2-up_1000|CCND1-up_595 CDH3-up_1001|CCND1-up_595 NCAM1-up_4684|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CDH2-up_1000|CCND2-up_894 NCAM1-up_4684|IGF1-up_3479 CD274-down_29126|IGF1-up_3479 CDH2-up_1000|S1PR1-down_1901 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|GADD45B-down_4616 CLDN1-up_9076|IGF1-up_3479 CLDN5-down_7122|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 NCAM1-up_4684|IGF1-up_3479 SELL-down_6402|IGF1-up_3479 VCAM1-up_7412|TGFB3-up_7043 ITGB8-up_3696|TGFB3-up_7043 NCAM1-up_4684|S1PR1-down_1901 SELL-down_6402|S1PR1-down_1901 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04068	hsa04550	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0	CCND1-up FZD5-down|CCND1-up ID1-down|CCND1-up IGF1-up|CCND1-up JAK1-down|CCND1-up LIFR-down|CCND1-up SOX2-up|CCND2-up FZD5-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up SOX2-up|FBXO32-up IGF1-up|GADD45B-down JAK1-down|TGFB3-up ID1-down|IGF1-up IRS2-down|IGF1-up SOD2-down|IRS2-down JAK1-down|S1PR1-down JAK1-down	CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND1-up_595 IGF1-up_3479|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LIFR-down_3977|CCND1-up_595 SOX2-up_6657|CCND2-up_894 FZD5-down_7855|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOX2-up_6657|FBXO32-up_114907 IGF1-up_3479|GADD45B-down_4616 JAK1-down_3716|TGFB3-up_7043 ID1-down_3397|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 SOD2-down_6648|IRS2-down_8660 JAK1-down_3716|S1PR1-down_1901 JAK1-down_3716
hsa04068	hsa04610	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.003	CCND1-up CFH-up|CCND1-up PLAU-up|CCND1-up SERPINE1-down|CCND2-up PLAU-up|CCND2-up SERPINE1-down|IGF1-up CFH-up|IGF1-up F3-down|SOD2-down F3-down|GADD45B-down PLAU-up|GADD45B-down SERPINE1-down|IGF1-up SERPINE1-down|IRS2-down SERPINE1-down|TGFB3-up PLAU-up|S1PR1-down TFPI-down|TGFB3-up SERPINE1-down	CCND1-up_595 CFH-up_3075|CCND1-up_595 PLAU-up_5328|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 PLAU-up_5328|CCND2-up_894 SERPINE1-down_5054|IGF1-up_3479 CFH-up_3075|IGF1-up_3479 F3-down_2152|SOD2-down_6648 F3-down_2152|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 SERPINE1-down_5054|IGF1-up_3479 SERPINE1-down_5054|IRS2-down_8660 SERPINE1-down_5054|TGFB3-up_7043 PLAU-up_5328|S1PR1-down_1901 TFPI-down_7035|TGFB3-up_7043 SERPINE1-down_5054
hsa04068	hsa04668	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	CCND1-up JUN-down|CCND1-up MAP3K8-down|CCND1-up SOCS3-down|CCND1-up VCAM1-up|CCND2-up CXCL2-down|CCND2-up JUN-down|CCND2-up MAP3K8-down|CCND2-up SOCS3-down|GADD45B-down CXCL2-down|IGF1-up CXCL2-down|IRS2-down CXCL2-down|S1PR1-down CXCL2-down|SOD2-down CXCL2-down|S1PR1-down CXCL3-down|FBXO32-up JUN-down|FBXO32-up SOCS3-down|GADD45B-down IL18R1-down|GADD45B-down JUN-down|GADD45B-down MAP3K8-down|GADD45B-down SOCS3-down|GADD45B-down VCAM1-up|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|TGFB3-up JUN-down|PRKAA2-up MAP3K8-down|SOD2-down MAP3K8-down|S1PR1-down VCAM1-up|SOD2-down SOCS3-down|TGFB3-up VCAM1-up	CCND1-up_595 JUN-down_3725|CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 SOCS3-down_9021|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL2-down_2920|CCND2-up_894 JUN-down_3725|CCND2-up_894 MAP3K8-down_1326|CCND2-up_894 SOCS3-down_9021|GADD45B-down_4616 CXCL2-down_2920|IGF1-up_3479 CXCL2-down_2920|IRS2-down_8660 CXCL2-down_2920|S1PR1-down_1901 CXCL2-down_2920|SOD2-down_6648 CXCL2-down_2920|S1PR1-down_1901 CXCL3-down_2921|FBXO32-up_114907 JUN-down_3725|FBXO32-up_114907 SOCS3-down_9021|GADD45B-down_4616 IL18R1-down_8809|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MAP3K8-down_1326|GADD45B-down_4616 SOCS3-down_9021|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|PRKAA2-up_5563 MAP3K8-down_1326|SOD2-down_6648 MAP3K8-down_1326|S1PR1-down_1901 VCAM1-up_7412|SOD2-down_6648 SOCS3-down_9021|TGFB3-up_7043 VCAM1-up_7412
hsa04068	hsa04670	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0.003	CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|CCND2-up CXCL12-up|CCND2-up MMP2-up|GADD45B-down CLDN1-up|IGF1-up CLDN5-down|GADD45B-down CXCL12-up|IGF1-up CXCL12-up|S1PR1-down CXCL12-up|SOD2-down CXCL12-up|TGFB3-up CXCL12-up|GADD45B-down MMP2-up|GADD45B-down VCAM1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up|S1PR1-down MMP2-up|SOD2-down MMP2-up|TGFB3-up MMP2-up|S1PR1-down VCAM1-up|TGFB3-up THY1-up|TGFB3-up VCAM1-up	CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP2-up_4313|GADD45B-down_4616 CLDN1-up_9076|IGF1-up_3479 CLDN5-down_7122|GADD45B-down_4616 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|S1PR1-down_1901 CXCL12-up_6387|SOD2-down_6648 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412|S1PR1-down_1901 MMP2-up_4313|SOD2-down_6648 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|S1PR1-down_1901 VCAM1-up_7412|TGFB3-up_7043 THY1-up_7070|TGFB3-up_7043 VCAM1-up_7412
hsa04068	hsa04915	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.007	CCND1-up HBEGF-down|CCND1-up HSPA1A-down|CCND1-up JUN-down|CCND1-up MMP2-up|CCND2-up HBEGF-down|CCND2-up JUN-down|CCND2-up MMP2-up|FBXO32-up JUN-down|GADD45B-down HBEGF-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|IGF1-up HBEGF-down|TGFB3-up HBEGF-down|IGF1-up HSPA1A-down|SOD2-down HSPA1A-down|SOD2-down HSPA1B-down|IGF1-up JUN-down|IGF1-up MMP2-up|IRS2-down JUN-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|TGFB3-up JUN-down|S1PR1-down MMP2-up|SOD2-down MMP2-up|TGFB3-up MMP2-up	CCND1-up_595 HBEGF-down_1839|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP2-up_4313|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|FBXO32-up_114907 JUN-down_3725|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|IGF1-up_3479 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|IGF1-up_3479 HSPA1A-down_3303|SOD2-down_6648 HSPA1A-down_3303|SOD2-down_6648 HSPA1B-down_3304|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IRS2-down_8660 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|S1PR1-down_1901 MMP2-up_4313|SOD2-down_6648 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313
hsa04068	hsa04933	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.001	CCND1-up GADD45B-down|CCND1-up IRS2-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up JUN-down|CCND2-up MMP2-up|CCND2-up SERPINE1-down|CCND2-up TGFB3-up|IGF1-up COL1A1-up|IGF1-up COL1A2-up|IGF1-up COL3A1-up|IGF1-up F3-down|SOD2-down F3-down|FBXO32-up JUN-down|IGF1-up FIGF-down|S1PR1-down FIGF-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|GADD45B-down SERPINE1-down|GADD45B-down VCAM1-up|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|IRS2-down JUN-down|IRS2-down SERPINE1-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|S1PR1-down MMP2-up|SOD2-down MMP2-up|S1PR1-down VCAM1-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 IRS2-down_8660|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|CCND2-up_894 SERPINE1-down_5054|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|IGF1-up_3479 COL3A1-up_1281|IGF1-up_3479 F3-down_2152|SOD2-down_6648 F3-down_2152|FBXO32-up_114907 JUN-down_3725|IGF1-up_3479 FIGF-down_2277|S1PR1-down_1901 FIGF-down_2277|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 SERPINE1-down_5054|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SERPINE1-down_5054|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|S1PR1-down_1901 MMP2-up_4313|SOD2-down_6648 MMP2-up_4313|S1PR1-down_1901 VCAM1-up_7412
hsa04068	hsa04978	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.037	CCND1-up HMOX1-down|CCND1-up TF-up|CCND2-up HMOX1-down|CCND2-up TF-up|FBXO32-up HMOX1-down|GADD45B-down HMOX1-down|GADD45B-down MT1X-down|IGF1-up HMOX1-down|IRS2-down HMOX1-down|SOD2-down HMOX1-down|IGF1-up TF-up|TGFB3-up TF-up	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|CCND2-up_894 HMOX1-down_3162|CCND2-up_894 TF-up_7018|FBXO32-up_114907 HMOX1-down_3162|GADD45B-down_4616 HMOX1-down_3162|GADD45B-down_4616 MT1X-down_4501|IGF1-up_3479 HMOX1-down_3162|IRS2-down_8660 HMOX1-down_3162|SOD2-down_6648 HMOX1-down_3162|IGF1-up_3479 TF-up_7018|TGFB3-up_7043 TF-up_7018
hsa04068	hsa05145	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.04	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up LDLR-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|GADD45B-down JAK1-down|IGF1-up HSPA1A-down|SOD2-down HSPA1A-down|SOD2-down HSPA1B-down|IGF1-up JAK1-down|IGF1-up LDLR-down|IGF1-up TGFB3-up|IRS2-down JAK1-down|IRS2-down LDLR-down|S1PR1-down JAK1-down	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 LDLR-down_3949|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|GADD45B-down_4616 JAK1-down_3716|IGF1-up_3479 HSPA1A-down_3303|SOD2-down_6648 HSPA1A-down_3303|SOD2-down_6648 HSPA1B-down_3304|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 TGFB3-up_7043|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 LDLR-down_3949|S1PR1-down_1901 JAK1-down_3716
hsa04068	hsa05152	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.003	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|IGF1-up CD74-up|GADD45B-down CLEC4E-down|GADD45B-down JAK1-down|IGF1-up JAK1-down|IGF1-up TGFB3-up|IRS2-down JAK1-down|S1PR1-down JAK1-down	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 CD74-up_972|GADD45B-down_4616 CLEC4E-down_26253|GADD45B-down_4616 JAK1-down_3716|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 TGFB3-up_7043|IRS2-down_8660 JAK1-down_3716|S1PR1-down_1901 JAK1-down_3716
hsa04068	hsa05164	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up SOCS3-down|FBXO32-up JUN-down|FBXO32-up SOCS3-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|IGF1-up HSPA1A-down|SOD2-down HSPA1A-down|SOD2-down HSPA1B-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PRSS1-up|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|S1PR1-down JAK1-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|TGFB3-up JUN-down|SOD2-down SOCS3-down	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|FBXO32-up_114907 JUN-down_3725|FBXO32-up_114907 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|IGF1-up_3479 HSPA1A-down_3303|SOD2-down_6648 HSPA1A-down_3303|SOD2-down_6648 HSPA1B-down_3304|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|S1PR1-down_1901 JAK1-down_3716|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|SOD2-down_6648 SOCS3-down_9021
hsa04068	hsa05166	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.012	CCND1-up GADD45B-down|CCND1-up IRS2-down|CCND2-up GADD45B-down|CCND2-up IRS2-down|FBXO32-up JUN-down|GADD45B-down IL1R2-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down MYB-up|GADD45B-down VCAM1-up|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up MYB-up|IGF1-up PDGFRA-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down MYB-up|IRS2-down PDGFRA-down|S1PR1-down JAK1-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|S1PR1-down PDGFRA-down|S1PR1-down VCAM1-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 IRS2-down_8660|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 IRS2-down_8660|FBXO32-up_114907 JUN-down_3725|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MYB-up_4602|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MYB-up_4602|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 MYB-up_4602|IRS2-down_8660 PDGFRA-down_5156|S1PR1-down_1901 JAK1-down_3716|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|S1PR1-down_1901 PDGFRA-down_5156|S1PR1-down_1901 VCAM1-up_7412
hsa04068	hsa05168	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up SOCS3-down|IGF1-up CD74-up|FBXO32-up JUN-down|FBXO32-up SOCS3-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|S1PR1-down JAK1-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|TGFB3-up JUN-down|SOD2-down SOCS3-down	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|IGF1-up_3479 CD74-up_972|FBXO32-up_114907 JUN-down_3725|FBXO32-up_114907 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|S1PR1-down_1901 JAK1-down_3716|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|SOD2-down_6648 SOCS3-down_9021
hsa04068	hsa05200	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.005	CCND1-up GADD45B-down|CCND1-up IRS2-down|CCND2-up CXCL12-up|CCND2-up FZD5-down|CCND2-up HHIP-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up PDGFRA-down|CCND2-up TCF7L2-up|CCND2-up TGFB3-up|CCND2-up ZBTB16-down|GADD45B-down CXCL12-up|S1PR1-down CXCL12-up|SOD2-down CXCL12-up|GADD45B-down DAPK2-down|PRKAA2-up DAPK2-down|FBXO32-up IGF1-up|FBXO32-up JUN-down|S1PR1-down FIGF-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|IGF1-up IRS2-down|IGF1-up SOD2-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down PDGFRA-down|IRS2-down TCF7L2-up|S1PR1-down JAK1-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|S1PR1-down MMP1-up|SOD2-down MMP1-up|S1PR1-down MMP2-up|SOD2-down MMP2-up|S1PR1-down PDGFRA-down|SOD2-down ZBTB16-down	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 IRS2-down_8660|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HHIP-down_64399|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 TCF7L2-up_6934|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 ZBTB16-down_7704|GADD45B-down_4616 CXCL12-up_6387|S1PR1-down_1901 CXCL12-up_6387|SOD2-down_6648 CXCL12-up_6387|GADD45B-down_4616 DAPK2-down_23604|PRKAA2-up_5563 DAPK2-down_23604|FBXO32-up_114907 IGF1-up_3479|FBXO32-up_114907 JUN-down_3725|S1PR1-down_1901 FIGF-down_2277|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 SOD2-down_6648|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 PDGFRA-down_5156|IRS2-down_8660 TCF7L2-up_6934|S1PR1-down_1901 JAK1-down_3716|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|S1PR1-down_1901 MMP1-up_4312|SOD2-down_6648 MMP1-up_4312|S1PR1-down_1901 MMP2-up_4313|SOD2-down_6648 MMP2-up_4313|S1PR1-down_1901 PDGFRA-down_5156|SOD2-down_6648 ZBTB16-down_7704
hsa04068	hsa05202	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.008	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up GADD45B-down|CCND2-up IRS2-down|FBXO32-up IGF1-up|FBXO32-up SIX1-up|IRS2-down FLT1-down|S1PR1-down FLT1-down|TGFB3-up FLT1-down|GADD45B-down IL1R2-down|GADD45B-down NFKBIZ-down|GADD45B-down PLAU-up|IGF1-up IRS2-down|IGF1-up SOD2-down|IRS2-down SIX1-up|SOD2-down NFKBIZ-down|TGFB3-up PLAU-up|TGFB3-up SIX1-up|SOD2-down ZBTB16-down	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 IRS2-down_8660|FBXO32-up_114907 IGF1-up_3479|FBXO32-up_114907 SIX1-up_6495|IRS2-down_8660 FLT1-down_2321|S1PR1-down_1901 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 NFKBIZ-down_64332|GADD45B-down_4616 PLAU-up_5328|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 SOD2-down_6648|IRS2-down_8660 SIX1-up_6495|SOD2-down_6648 NFKBIZ-down_64332|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SIX1-up_6495|SOD2-down_6648 ZBTB16-down_7704
hsa04068	hsa05205	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.003	FBXO32-up ANK2-up|SOD2-down ANK2-up|CCND1-up GADD45B-down|CCND1-up IRS2-down|CCND2-up FZD5-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|CCND2-up THBS1-down|FBXO32-up IGF1-up|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down PLAU-up|GADD45B-down THBS1-down|TGFB3-up HBEGF-down|IGF1-up IRS2-down|IGF1-up SOD2-down|S1PR1-down MMP2-up|SOD2-down MMP2-up|TGFB3-up MMP2-up|TGFB3-up PLAU-up|S1PR1-down THBS1-down|TGFB3-up THBS1-down	FBXO32-up_114907 ANK2-up_287|SOD2-down_6648 ANK2-up_287|CCND1-up_595 GADD45B-down_4616|CCND1-up_595 IRS2-down_8660|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|CCND2-up_894 THBS1-down_7057|FBXO32-up_114907 IGF1-up_3479|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|TGFB3-up_7043 HBEGF-down_1839|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 SOD2-down_6648|S1PR1-down_1901 MMP2-up_4313|SOD2-down_6648 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|TGFB3-up_7043 PLAU-up_5328|S1PR1-down_1901 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057
hsa04068	hsa05206	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.017	CCND1-up GADD45B-down|CCND2-up GADD45B-down|IGF1-up CYP24A1-up|FBXO32-up HMOX1-down|FBXO32-up SERPINB5-up|GADD45B-down HMOX1-down|GADD45B-down MCL1-down|GADD45B-down PLAU-up|GADD45B-down THBS1-down|IGF1-up HMOX1-down|SOD2-down HMOX1-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|IGF1-up TNC-up|PRKAA2-up MCL1-down|S1PR1-down MCL1-down|SOD2-down MCL1-down|S1PR1-down PDGFRA-down|TGFB3-up PDGFRA-down|TGFB3-up PLAU-up|S1PR1-down THBS1-down|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	CCND1-up_595 GADD45B-down_4616|CCND2-up_894 GADD45B-down_4616|IGF1-up_3479 CYP24A1-up_1591|FBXO32-up_114907 HMOX1-down_3162|FBXO32-up_114907 SERPINB5-up_5268|GADD45B-down_4616 HMOX1-down_3162|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 HMOX1-down_3162|SOD2-down_6648 HMOX1-down_3162|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 TNC-up_3371|PRKAA2-up_5563 MCL1-down_4170|S1PR1-down_1901 MCL1-down_4170|SOD2-down_6648 MCL1-down_4170|S1PR1-down_1901 PDGFRA-down_5156|TGFB3-up_7043 PDGFRA-down_5156|TGFB3-up_7043 PLAU-up_5328|S1PR1-down_1901 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa04068	hsa05219	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCND1-up GADD45B-down|CCND1-up IRS2-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up THBS1-down|GADD45B-down DAPK2-down|PRKAA2-up DAPK2-down|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down THBS1-down|IGF1-up HBEGF-down|TGFB3-up HBEGF-down|IGF1-up MMP1-up|IGF1-up MMP2-up|IGF1-up THBS1-down|S1PR1-down MMP1-up|SOD2-down MMP1-up|TGFB3-up MMP1-up|S1PR1-down MMP2-up|SOD2-down MMP2-up|TGFB3-up MMP2-up|S1PR1-down THBS1-down|TGFB3-up THBS1-down	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 IRS2-down_8660|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 THBS1-down_7057|GADD45B-down_4616 DAPK2-down_23604|PRKAA2-up_5563 DAPK2-down_23604|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THBS1-down_7057|S1PR1-down_1901 MMP1-up_4312|SOD2-down_6648 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|S1PR1-down_1901 MMP2-up_4313|SOD2-down_6648 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|S1PR1-down_1901 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057
hsa04068	hsa05323	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.001	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up FLT1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|IGF1-up CTSK-up|SOD2-down CTSK-up|GADD45B-down CXCL12-up|IGF1-up CXCL12-up|S1PR1-down CXCL12-up|SOD2-down CXCL12-up|FBXO32-up JUN-down|IGF1-up FLT1-down|IRS2-down FLT1-down|S1PR1-down FLT1-down|GADD45B-down JUN-down|IGF1-up JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|IRS2-down JUN-down|PRKAA2-up JUN-down|S1PR1-down JUN-down|SOD2-down JUN-down|S1PR1-down MMP1-up|SOD2-down MMP1-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 CTSK-up_1513|SOD2-down_6648 CTSK-up_1513|GADD45B-down_4616 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|S1PR1-down_1901 CXCL12-up_6387|SOD2-down_6648 CXCL12-up_6387|FBXO32-up_114907 JUN-down_3725|IGF1-up_3479 FLT1-down_2321|IRS2-down_8660 FLT1-down_2321|S1PR1-down_1901 FLT1-down_2321|GADD45B-down_4616 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|IRS2-down_8660 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|SOD2-down_6648 JUN-down_3725|S1PR1-down_1901 MMP1-up_4312|SOD2-down_6648 MMP1-up_4312
hsa04068	hsa05412	FoxO signaling pathway - Homo sapiens (human)	GADD45B,IRS2,S1PR1,SOD2,CCND1,CCND2,FBXO32,IGF1,PRKAA2,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.001	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|IGF1-up CDH2-up|S1PR1-down CDH2-up|TGFB3-up CDH2-up|FBXO32-up DES-up|TGFB3-up DES-up|IGF1-up TCF7L2-up|IRS2-down TCF7L2-up|TGFB3-up ITGB8-up|TGFB3-up TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|IGF1-up_3479 CDH2-up_1000|S1PR1-down_1901 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|FBXO32-up_114907 DES-up_1674|TGFB3-up_7043 DES-up_1674|IGF1-up_3479 TCF7L2-up_6934|IRS2-down_8660 TCF7L2-up_6934|TGFB3-up_7043 ITGB8-up_3696|TGFB3-up_7043 TCF7L2-up_6934
hsa04080	hsa04151	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	0.047	ADRB1-down FLT1-down|ADRB1-down MCL1-down|ADRB1-down MYB-up|ADRB1-down SPP1-up|APLNR-up CCND1-up|APLNR-up COL1A1-up|APLNR-up COL1A2-up|APLNR-up FLT1-down|APLNR-up IGF1-up|APLNR-up TNC-up|EDNRB-down CCND1-up|EDNRB-down COL1A2-up|EDNRB-down FLT1-down|EDNRB-down IGF1-up|EDNRB-down MCL1-down|EDNRB-down SPP1-up|EDNRB-down THBS1-down|EDNRB-down TNC-up|S1PR1-down FIGF-down|S1PR1-down FLT1-down|FPR1-down MCL1-down|FPR2-down IGF1-up|GABBR1-up SPP1-up|GABBR2-up JAK1-down|GABBR2-up SPP1-up|GRIA1-down IGF1-up|GRIA1-down SPP1-up|PRSS1-up IGF1-up|S1PR1-down JAK1-down|RXFP1-down MCL1-down|S1PR1-down MCL1-down|RXFP1-down MYB-up|P2RY1-down SPP1-up|S1PR1-down PDGFRA-down|S1PR1-down THBS1-down	ADRB1-down_153 FLT1-down_2321|ADRB1-down_153 MCL1-down_4170|ADRB1-down_153 MYB-up_4602|ADRB1-down_153 SPP1-up_6696|APLNR-up_187 CCND1-up_595|APLNR-up_187 COL1A1-up_1277|APLNR-up_187 COL1A2-up_1278|APLNR-up_187 FLT1-down_2321|APLNR-up_187 IGF1-up_3479|APLNR-up_187 TNC-up_3371|EDNRB-down_1910 CCND1-up_595|EDNRB-down_1910 COL1A2-up_1278|EDNRB-down_1910 FLT1-down_2321|EDNRB-down_1910 IGF1-up_3479|EDNRB-down_1910 MCL1-down_4170|EDNRB-down_1910 SPP1-up_6696|EDNRB-down_1910 THBS1-down_7057|EDNRB-down_1910 TNC-up_3371|S1PR1-down_1901 FIGF-down_2277|S1PR1-down_1901 FLT1-down_2321|FPR1-down_2357 MCL1-down_4170|FPR2-down_2358 IGF1-up_3479|GABBR1-up_2550 SPP1-up_6696|GABBR2-up_9568 JAK1-down_3716|GABBR2-up_9568 SPP1-up_6696|GRIA1-down_2890 IGF1-up_3479|GRIA1-down_2890 SPP1-up_6696|PRSS1-up_5644 IGF1-up_3479|S1PR1-down_1901 JAK1-down_3716|RXFP1-down_59350 MCL1-down_4170|S1PR1-down_1901 MCL1-down_4170|RXFP1-down_59350 MYB-up_4602|P2RY1-down_5028 SPP1-up_6696|S1PR1-down_1901 PDGFRA-down_5156|S1PR1-down_1901 THBS1-down_7057
hsa04080	hsa04360	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0.017	APLNR-up CXCL12-up|APLNR-up EPHA3-up|FPR1-down BOC-up|FPR2-down BOC-up|EDNRB-down CXCL12-up|FPR1-down CXCL12-up|FPR2-down CXCL12-up|GABBR2-up CXCL12-up|S1PR1-down CXCL12-up|VIPR1-down CXCL12-up|GRIA1-down EPHA3-up|RXFP1-down RND1-down	APLNR-up_187 CXCL12-up_6387|APLNR-up_187 EPHA3-up_2042|FPR1-down_2357 BOC-up_91653|FPR2-down_2358 BOC-up_91653|EDNRB-down_1910 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|FPR2-down_2358 CXCL12-up_6387|GABBR2-up_9568 CXCL12-up_6387|S1PR1-down_1901 CXCL12-up_6387|VIPR1-down_7433 CXCL12-up_6387|GRIA1-down_2890 EPHA3-up_2042|RXFP1-down_59350 RND1-down_27289
hsa04080	hsa04514	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0.011	APLNR-up CLDN5-down|APLNR-up VCAM1-up|EDNRB-down CDH2-up|GABBR2-up CDH2-up|GRIA1-down CDH2-up|PRSS1-up CDH2-up|S1PR1-down CDH2-up|EDNRB-down CLDN1-up|VIPR1-down CLDN1-up|EDNRB-down CLDN5-down|EDNRB-down NCAM1-up|EDNRB-down VCAM1-up|FPR2-down VCAM1-up|S1PR1-down SELL-down|S1PR1-down VCAM1-up	APLNR-up_187 CLDN5-down_7122|APLNR-up_187 VCAM1-up_7412|EDNRB-down_1910 CDH2-up_1000|GABBR2-up_9568 CDH2-up_1000|GRIA1-down_2890 CDH2-up_1000|PRSS1-up_5644 CDH2-up_1000|S1PR1-down_1901 CDH2-up_1000|EDNRB-down_1910 CLDN1-up_9076|VIPR1-down_7433 CLDN1-up_9076|EDNRB-down_1910 CLDN5-down_7122|EDNRB-down_1910 NCAM1-up_4684|EDNRB-down_1910 VCAM1-up_7412|FPR2-down_2358 VCAM1-up_7412|S1PR1-down_1901 SELL-down_6402|S1PR1-down_1901 VCAM1-up_7412
hsa04080	hsa04550	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.035	APLNR-up IGF1-up|APLNR-up SOX2-up|EDNRB-down IGF1-up|FPR2-down IGF1-up|GABBR2-up FZD5-down|GABBR2-up JAK1-down|GRIA1-down IGF1-up|PRSS1-up IGF1-up|S1PR1-down JAK1-down|P2RY1-down SOX2-up	APLNR-up_187 IGF1-up_3479|APLNR-up_187 SOX2-up_6657|EDNRB-down_1910 IGF1-up_3479|FPR2-down_2358 IGF1-up_3479|GABBR2-up_9568 FZD5-down_7855|GABBR2-up_9568 JAK1-down_3716|GRIA1-down_2890 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|S1PR1-down_1901 JAK1-down_3716|P2RY1-down_5028 SOX2-up_6657
hsa04080	hsa04610	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.003	ADRB1-down SERPINE1-down|ADRB1-down TFPI-down|APLNR-up CFH-up|EDNRB-down CFH-up|EDNRB-down SERPINE1-down|EDNRB-down TFPI-down|GRIA1-down F3-down|P2RY1-down F3-down|FPR1-down SERPIND1-up|PRSS1-up PLAU-up|VIPR1-down PLAU-up|PRSS1-up SERPINE1-down|S1PR1-down TFPI-down	ADRB1-down_153 SERPINE1-down_5054|ADRB1-down_153 TFPI-down_7035|APLNR-up_187 CFH-up_3075|EDNRB-down_1910 CFH-up_3075|EDNRB-down_1910 SERPINE1-down_5054|EDNRB-down_1910 TFPI-down_7035|GRIA1-down_2890 F3-down_2152|P2RY1-down_5028 F3-down_2152|FPR1-down_2357 SERPIND1-up_3053|PRSS1-up_5644 PLAU-up_5328|VIPR1-down_7433 PLAU-up_5328|PRSS1-up_5644 SERPINE1-down_5054|S1PR1-down_1901 TFPI-down_7035
hsa04080	hsa04668	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.001	ADRB1-down MAP3K8-down|APLNR-up CXCL2-down|APLNR-up CXCL3-down|APLNR-up JUN-down|APLNR-up VCAM1-up|FPR1-down CXCL2-down|FPR2-down CXCL2-down|S1PR1-down CXCL2-down|FPR1-down CXCL3-down|FPR2-down CXCL3-down|S1PR1-down CXCL3-down|EDNRB-down JUN-down|EDNRB-down VCAM1-up|FPR2-down JUN-down|FPR2-down SOCS3-down|FPR2-down VCAM1-up|GRIA1-down JUN-down|PRSS1-up JUN-down|RXFP1-down JUN-down|S1PR1-down JUN-down|VIPR1-down JUN-down|RXFP1-down MAP3K8-down|S1PR1-down VCAM1-up	ADRB1-down_153 MAP3K8-down_1326|APLNR-up_187 CXCL2-down_2920|APLNR-up_187 CXCL3-down_2921|APLNR-up_187 JUN-down_3725|APLNR-up_187 VCAM1-up_7412|FPR1-down_2357 CXCL2-down_2920|FPR2-down_2358 CXCL2-down_2920|S1PR1-down_1901 CXCL2-down_2920|FPR1-down_2357 CXCL3-down_2921|FPR2-down_2358 CXCL3-down_2921|S1PR1-down_1901 CXCL3-down_2921|EDNRB-down_1910 JUN-down_3725|EDNRB-down_1910 VCAM1-up_7412|FPR2-down_2358 JUN-down_3725|FPR2-down_2358 SOCS3-down_9021|FPR2-down_2358 VCAM1-up_7412|GRIA1-down_2890 JUN-down_3725|PRSS1-up_5644 JUN-down_3725|RXFP1-down_59350 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|VIPR1-down_7433 JUN-down_3725|RXFP1-down_59350 MAP3K8-down_1326|S1PR1-down_1901 VCAM1-up_7412
hsa04080	hsa04670	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	APLNR-up CLDN5-down|APLNR-up CXCL12-up|APLNR-up MMP2-up|APLNR-up VCAM1-up|EDNRB-down CLDN1-up|VIPR1-down CLDN1-up|EDNRB-down CLDN5-down|EDNRB-down CXCL12-up|FPR1-down CXCL12-up|FPR2-down CXCL12-up|GABBR2-up CXCL12-up|S1PR1-down CXCL12-up|VIPR1-down CXCL12-up|EDNRB-down MMP2-up|EDNRB-down VCAM1-up|FPR2-down MMP2-up|FPR2-down VCAM1-up|RXFP1-down MMP2-up|S1PR1-down MMP2-up|S1PR1-down VCAM1-up	APLNR-up_187 CLDN5-down_7122|APLNR-up_187 CXCL12-up_6387|APLNR-up_187 MMP2-up_4313|APLNR-up_187 VCAM1-up_7412|EDNRB-down_1910 CLDN1-up_9076|VIPR1-down_7433 CLDN1-up_9076|EDNRB-down_1910 CLDN5-down_7122|EDNRB-down_1910 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|FPR2-down_2358 CXCL12-up_6387|GABBR2-up_9568 CXCL12-up_6387|S1PR1-down_1901 CXCL12-up_6387|VIPR1-down_7433 CXCL12-up_6387|EDNRB-down_1910 MMP2-up_4313|EDNRB-down_1910 VCAM1-up_7412|FPR2-down_2358 MMP2-up_4313|FPR2-down_2358 VCAM1-up_7412|RXFP1-down_59350 MMP2-up_4313|S1PR1-down_1901 MMP2-up_4313|S1PR1-down_1901 VCAM1-up_7412
hsa04080	hsa04933	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.025	ADRB1-down SERPINE1-down|APLNR-up CCND1-up|APLNR-up COL1A1-up|APLNR-up COL1A2-up|APLNR-up JUN-down|APLNR-up MMP2-up|APLNR-up VCAM1-up|EDNRB-down CCND1-up|EDNRB-down COL1A2-up|EDNRB-down JUN-down|EDNRB-down MMP2-up|EDNRB-down SERPINE1-down|EDNRB-down VCAM1-up|GRIA1-down F3-down|P2RY1-down F3-down|S1PR1-down FIGF-down|FPR2-down JUN-down|FPR2-down MMP2-up|FPR2-down VCAM1-up|GRIA1-down JUN-down|PRSS1-up JUN-down|RXFP1-down JUN-down|S1PR1-down JUN-down|VIPR1-down JUN-down|RXFP1-down MMP2-up|S1PR1-down MMP2-up|PRSS1-up SERPINE1-down|S1PR1-down VCAM1-up	ADRB1-down_153 SERPINE1-down_5054|APLNR-up_187 CCND1-up_595|APLNR-up_187 COL1A1-up_1277|APLNR-up_187 COL1A2-up_1278|APLNR-up_187 JUN-down_3725|APLNR-up_187 MMP2-up_4313|APLNR-up_187 VCAM1-up_7412|EDNRB-down_1910 CCND1-up_595|EDNRB-down_1910 COL1A2-up_1278|EDNRB-down_1910 JUN-down_3725|EDNRB-down_1910 MMP2-up_4313|EDNRB-down_1910 SERPINE1-down_5054|EDNRB-down_1910 VCAM1-up_7412|GRIA1-down_2890 F3-down_2152|P2RY1-down_5028 F3-down_2152|S1PR1-down_1901 FIGF-down_2277|FPR2-down_2358 JUN-down_3725|FPR2-down_2358 MMP2-up_4313|FPR2-down_2358 VCAM1-up_7412|GRIA1-down_2890 JUN-down_3725|PRSS1-up_5644 JUN-down_3725|RXFP1-down_59350 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|VIPR1-down_7433 JUN-down_3725|RXFP1-down_59350 MMP2-up_4313|S1PR1-down_1901 MMP2-up_4313|PRSS1-up_5644 SERPINE1-down_5054|S1PR1-down_1901 VCAM1-up_7412
hsa04080	hsa05200	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.048	APLNR-up CCND1-up|APLNR-up CXCL12-up|APLNR-up IGF1-up|APLNR-up JUN-down|APLNR-up MMP2-up|FPR1-down CXCL12-up|FPR2-down CXCL12-up|GABBR2-up CXCL12-up|S1PR1-down CXCL12-up|VIPR1-down CXCL12-up|S1PR1-down FIGF-down|FPR2-down IGF1-up|FPR2-down JUN-down|FPR2-down MMP1-up|FPR2-down MMP2-up|GABBR2-up FZD5-down|GABBR2-up JAK1-down|GRIA1-down IGF1-up|GRIA1-down JUN-down|PRSS1-up IGF1-up|S1PR1-down JAK1-down|PRSS1-up JUN-down|RXFP1-down JUN-down|S1PR1-down JUN-down|VIPR1-down JUN-down|PRSS1-up MMP1-up|RXFP1-down MMP1-up|S1PR1-down MMP1-up|RXFP1-down MMP2-up|S1PR1-down MMP2-up|S1PR1-down PDGFRA-down|RXFP1-down ZBTB16-down	APLNR-up_187 CCND1-up_595|APLNR-up_187 CXCL12-up_6387|APLNR-up_187 IGF1-up_3479|APLNR-up_187 JUN-down_3725|APLNR-up_187 MMP2-up_4313|FPR1-down_2357 CXCL12-up_6387|FPR2-down_2358 CXCL12-up_6387|GABBR2-up_9568 CXCL12-up_6387|S1PR1-down_1901 CXCL12-up_6387|VIPR1-down_7433 CXCL12-up_6387|S1PR1-down_1901 FIGF-down_2277|FPR2-down_2358 IGF1-up_3479|FPR2-down_2358 JUN-down_3725|FPR2-down_2358 MMP1-up_4312|FPR2-down_2358 MMP2-up_4313|GABBR2-up_9568 FZD5-down_7855|GABBR2-up_9568 JAK1-down_3716|GRIA1-down_2890 IGF1-up_3479|GRIA1-down_2890 JUN-down_3725|PRSS1-up_5644 IGF1-up_3479|S1PR1-down_1901 JAK1-down_3716|PRSS1-up_5644 JUN-down_3725|RXFP1-down_59350 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|VIPR1-down_7433 JUN-down_3725|PRSS1-up_5644 MMP1-up_4312|RXFP1-down_59350 MMP1-up_4312|S1PR1-down_1901 MMP1-up_4312|RXFP1-down_59350 MMP2-up_4313|S1PR1-down_1901 MMP2-up_4313|S1PR1-down_1901 PDGFRA-down_5156|RXFP1-down_59350 ZBTB16-down_7704
hsa04080	hsa05323	Neuroactive ligand-receptor interaction - Homo sapiens (human)	ADRB1,EDNRB,FPR1,FPR2,GRIA1,P2RY1,RXFP1,S1PR1,VIPR1,APLNR,GABBR1,GABBR2,PRSS1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.001	ADRB1-down FLT1-down|APLNR-up CXCL12-up|APLNR-up FLT1-down|APLNR-up JUN-down|EDNRB-down CTSK-up|EDNRB-down CXCL12-up|FPR1-down CXCL12-up|FPR2-down CXCL12-up|GABBR2-up CXCL12-up|S1PR1-down CXCL12-up|VIPR1-down CXCL12-up|EDNRB-down FLT1-down|EDNRB-down JUN-down|EDNRB-down MMP1-up|S1PR1-down FLT1-down|FPR2-down JUN-down|FPR2-down MMP1-up|GRIA1-down JUN-down|PRSS1-up JUN-down|RXFP1-down JUN-down|S1PR1-down JUN-down|VIPR1-down JUN-down|PRSS1-up MMP1-up|RXFP1-down MMP1-up|S1PR1-down MMP1-up	ADRB1-down_153 FLT1-down_2321|APLNR-up_187 CXCL12-up_6387|APLNR-up_187 FLT1-down_2321|APLNR-up_187 JUN-down_3725|EDNRB-down_1910 CTSK-up_1513|EDNRB-down_1910 CXCL12-up_6387|FPR1-down_2357 CXCL12-up_6387|FPR2-down_2358 CXCL12-up_6387|GABBR2-up_9568 CXCL12-up_6387|S1PR1-down_1901 CXCL12-up_6387|VIPR1-down_7433 CXCL12-up_6387|EDNRB-down_1910 FLT1-down_2321|EDNRB-down_1910 JUN-down_3725|EDNRB-down_1910 MMP1-up_4312|S1PR1-down_1901 FLT1-down_2321|FPR2-down_2358 JUN-down_3725|FPR2-down_2358 MMP1-up_4312|GRIA1-down_2890 JUN-down_3725|PRSS1-up_5644 JUN-down_3725|RXFP1-down_59350 JUN-down_3725|S1PR1-down_1901 JUN-down_3725|VIPR1-down_7433 JUN-down_3725|PRSS1-up_5644 MMP1-up_4312|RXFP1-down_59350 MMP1-up_4312|S1PR1-down_1901 MMP1-up_4312
hsa04115	hsa04144	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	0	SERPINE1-down ADRB1-down|CCND1-up ARRB1-down|IGF1-up ARRB1-down|CCND1-up CAV2-down|SERPINB5-up CAV2-down|SERPINE1-down CAV2-down|CCND1-up CXCR2-down|CCND1-up FLT1-down|CCND1-up HSPA1A-down|CCND1-up LDLR-down|CCND1-up PDGFRA-down|CCND1-up TGFB3-up|CCND2-up FLT1-down|CCND2-up PDGFRA-down|CCND2-up TGFB3-up|GADD45B-down CXCR2-down|IGF1-up CXCR2-down|SERPINE1-down CXCR2-down|THBS1-down CXCR2-down|SERPINE1-down DNM1-up|IGF1-up FLT1-down|SERPINB5-up FLT1-down|SERPINE1-down FLT1-down|THBS1-down FLT1-down|IGF1-up HSPA1A-down|IGF1-up LDLR-down|IGF1-up PDGFRA-down|IGF1-up TGFB3-up|SERPINE1-down LDLR-down|THBS1-down LDLR-down|THBS1-down PDGFRA-down|SERPINE1-down TGFB3-up|THBS1-down TGFB3-up	SERPINE1-down_5054 ADRB1-down_153|CCND1-up_595 ARRB1-down_408|IGF1-up_3479 ARRB1-down_408|CCND1-up_595 CAV2-down_858|SERPINB5-up_5268 CAV2-down_858|SERPINE1-down_5054 CAV2-down_858|CCND1-up_595 CXCR2-down_3579|CCND1-up_595 FLT1-down_2321|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 LDLR-down_3949|CCND1-up_595 PDGFRA-down_5156|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 FLT1-down_2321|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 TGFB3-up_7043|GADD45B-down_4616 CXCR2-down_3579|IGF1-up_3479 CXCR2-down_3579|SERPINE1-down_5054 CXCR2-down_3579|THBS1-down_7057 CXCR2-down_3579|SERPINE1-down_5054 DNM1-up_1759|IGF1-up_3479 FLT1-down_2321|SERPINB5-up_5268 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|IGF1-up_3479 HSPA1A-down_3303|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 TGFB3-up_7043|SERPINE1-down_5054 LDLR-down_3949|THBS1-down_7057 LDLR-down_3949|THBS1-down_7057 PDGFRA-down_5156|SERPINE1-down_5054 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04115	hsa04310	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up SERPINE1-down|CCND1-up THBS1-down|CCND2-up GADD45B-down|CCND2-up PMAIP1-down|CCND2-up SERPINE1-down|CCND2-up THBS1-down|GADD45B-down JUN-down|IGF1-up JUN-down|IGF1-up MMP7-up|IGF1-up SERPINF1-up|IGF1-up SFRP2-up|IGF1-up SFRP4-up|IGF1-up TCF7L2-up|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINB5-up MMP7-up|SERPINE1-down MMP7-up|THBS1-down MMP7-up|PMAIP1-down TCF7L2-up|SERPINB5-up SERPINF1-up|SERPINE1-down SERPINF1-up|THBS1-down SERPINF1-up|THBS1-down SFRP2-up|THBS1-down SFRP4-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 SERPINE1-down_5054|CCND1-up_595 THBS1-down_7057|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 PMAIP1-down_5366|CCND2-up_894 SERPINE1-down_5054|CCND2-up_894 THBS1-down_7057|GADD45B-down_4616 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP7-up_4316|IGF1-up_3479 SERPINF1-up_5176|IGF1-up_3479 SFRP2-up_6423|IGF1-up_3479 SFRP4-up_6424|IGF1-up_3479 TCF7L2-up_6934|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINB5-up_5268 MMP7-up_4316|SERPINE1-down_5054 MMP7-up_4316|THBS1-down_7057 MMP7-up_4316|PMAIP1-down_5366 TCF7L2-up_6934|SERPINB5-up_5268 SERPINF1-up_5176|SERPINE1-down_5054 SERPINF1-up_5176|THBS1-down_7057 SERPINF1-up_5176|THBS1-down_7057 SFRP2-up_6423|THBS1-down_7057 SFRP4-up_6424
hsa04115	hsa04350	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0.006	CCND1-up ID1-down|CCND1-up SMAD6-down|CCND1-up TGFB3-up|CCND2-up SMAD6-down|CCND2-up TGFB3-up|GADD45B-down THBS1-down|IGF1-up ID1-down|SERPINE1-down ID1-down|IGF1-up SMAD6-down|IGF1-up TGFB3-up|SERPINE1-down LTBP1-up|SERPINE1-down SMAD6-down|SERPINE1-down TGFB3-up|SERPINE1-down THBS1-down	CCND1-up_595 ID1-down_3397|CCND1-up_595 SMAD6-down_4091|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 SMAD6-down_4091|CCND2-up_894 TGFB3-up_7043|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 ID1-down_3397|SERPINE1-down_5054 ID1-down_3397|IGF1-up_3479 SMAD6-down_4091|IGF1-up_3479 TGFB3-up_7043|SERPINE1-down_5054 LTBP1-up_4052|SERPINE1-down_5054 SMAD6-down_4091|SERPINE1-down_5054 TGFB3-up_7043|SERPINE1-down_5054 THBS1-down_7057
hsa04115	hsa04380	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0	CCND1-up CTSK-up|CCND1-up FHL2-up|CCND1-up FOSL2-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up FOSL2-down|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up SOCS3-down|IGF1-up CTSK-up|SERPINB5-up CTSK-up|SERPINE1-down CTSK-up|THBS1-down CTSK-up|IGF1-up FHL2-up|SERPINE1-down FHL2-up|IGF1-up FOSL2-down|SERPINE1-down FOSL2-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|SERPINE1-down JAK1-down|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINE1-down SOCS3-down|THBS1-down SOCS3-down	CCND1-up_595 CTSK-up_1513|CCND1-up_595 FHL2-up_2274|CCND1-up_595 FOSL2-down_2355|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 FOSL2-down_2355|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|IGF1-up_3479 CTSK-up_1513|SERPINB5-up_5268 CTSK-up_1513|SERPINE1-down_5054 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|IGF1-up_3479 FHL2-up_2274|SERPINE1-down_5054 FHL2-up_2274|IGF1-up_3479 FOSL2-down_2355|SERPINE1-down_5054 FOSL2-down_2355|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|SERPINE1-down_5054 JAK1-down_3716|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINE1-down_5054 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021
hsa04115	hsa04390	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.002	CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up THBS1-down|CCND2-up GADD45B-down|CCND2-up PMAIP1-down|CCND2-up THBS1-down|GADD45B-down SERPINE1-down|IGF1-up ID1-down|THBS1-down ID1-down|IGF1-up SOX2-up|IGF1-up TCF7L2-up|IGF1-up TGFB3-up|PMAIP1-down TCF7L2-up|THBS1-down SOX2-up|THBS1-down TGFB3-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 THBS1-down_7057|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 PMAIP1-down_5366|CCND2-up_894 THBS1-down_7057|GADD45B-down_4616 SERPINE1-down_5054|IGF1-up_3479 ID1-down_3397|THBS1-down_7057 ID1-down_3397|IGF1-up_3479 SOX2-up_6657|IGF1-up_3479 TCF7L2-up_6934|IGF1-up_3479 TGFB3-up_7043|PMAIP1-down_5366 TCF7L2-up_6934|THBS1-down_7057 SOX2-up_6657|THBS1-down_7057 TGFB3-up_7043
hsa04115	hsa04512	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0.001	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up ITGB4-up|CCND1-up LAMA3-down|CCND1-up SPP1-up|CCND1-up THBS2-up|CCND1-up TNC-up|CCND2-up COL1A2-up|CCND2-up TNC-up|IGF1-up COL1A1-up|SERPINE1-down COL1A1-up|IGF1-up COL1A2-up|SERPINE1-down COL1A2-up|IGF1-up COMP-up|SERPINE1-down COMP-up|GADD45B-down THBS1-down|IGF1-up SPP1-up|IGF1-up THBS2-up|IGF1-up TNC-up|SERPINB5-up ITGB4-up|SERPINE1-down LAMA3-down|SERPINB5-up SPP1-up|SERPINB5-up THBS2-up|SERPINB5-up TNC-up|SERPINE1-down SPP1-up|SERPINE1-down THBS1-down|SERPINE1-down THBS2-up|SERPINE1-down TNC-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 SPP1-up_6696|CCND1-up_595 THBS2-up_7058|CCND1-up_595 TNC-up_3371|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 TNC-up_3371|IGF1-up_3479 COL1A1-up_1277|SERPINE1-down_5054 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|SERPINE1-down_5054 COL1A2-up_1278|IGF1-up_3479 COMP-up_1311|SERPINE1-down_5054 COMP-up_1311|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 SPP1-up_6696|IGF1-up_3479 THBS2-up_7058|IGF1-up_3479 TNC-up_3371|SERPINB5-up_5268 ITGB4-up_3691|SERPINE1-down_5054 LAMA3-down_3909|SERPINB5-up_5268 SPP1-up_6696|SERPINB5-up_5268 THBS2-up_7058|SERPINB5-up_5268 TNC-up_3371|SERPINE1-down_5054 SPP1-up_6696|SERPINE1-down_5054 THBS1-down_7057|SERPINE1-down_5054 THBS2-up_7058|SERPINE1-down_5054 TNC-up_3371
hsa04115	hsa04514	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CCND1-up CD274-down|CCND1-up CDH2-up|CCND1-up CDH3-up|CCND1-up NCAM1-up|CCND1-up VCAM1-up|CCND2-up CDH2-up|CCND2-up NCAM1-up|IGF1-up CD274-down|IGF1-up CDH2-up|SERPINB5-up CDH2-up|SERPINE1-down CDH2-up|THBS1-down CDH2-up|SERPINB5-up CLDN18-down|GADD45B-down CLDN1-up|THBS1-down CLDN1-up|IGF1-up CLDN5-down|SERPINE1-down CLDN5-down|THBS1-down CLDN5-down|GADD45B-down VCAM1-up|IGF1-up NCAM1-up|IGF1-up SELL-down|IGF1-up VCAM1-up|THBS1-down ITGB8-up|SERPINE1-down NCAM1-up|THBS1-down NCAM1-up|SERPINB5-up SELL-down|SERPINE1-down SELL-down|SERPINE1-down VCAM1-up|THBS1-down VCAM1-up	CCND1-up_595 CD274-down_29126|CCND1-up_595 CDH2-up_1000|CCND1-up_595 CDH3-up_1001|CCND1-up_595 NCAM1-up_4684|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CDH2-up_1000|CCND2-up_894 NCAM1-up_4684|IGF1-up_3479 CD274-down_29126|IGF1-up_3479 CDH2-up_1000|SERPINB5-up_5268 CDH2-up_1000|SERPINE1-down_5054 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|SERPINB5-up_5268 CLDN18-down_51208|GADD45B-down_4616 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|IGF1-up_3479 CLDN5-down_7122|SERPINE1-down_5054 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 NCAM1-up_4684|IGF1-up_3479 SELL-down_6402|IGF1-up_3479 VCAM1-up_7412|THBS1-down_7057 ITGB8-up_3696|SERPINE1-down_5054 NCAM1-up_4684|THBS1-down_7057 NCAM1-up_4684|SERPINB5-up_5268 SELL-down_6402|SERPINE1-down_5054 SELL-down_6402|SERPINE1-down_5054 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412
hsa04115	hsa04550	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.003	CCND1-up FZD5-down|CCND1-up ID1-down|CCND1-up IGF1-up|CCND1-up JAK1-down|CCND1-up LIFR-down|CCND1-up SOX2-up|CCND2-up FZD5-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up SOX2-up|GADD45B-down JAK1-down|SERPINE1-down ID1-down|THBS1-down ID1-down|IGF1-up SERPINE1-down|IGF1-up THBS1-down|SERPINE1-down JAK1-down|THBS1-down SOX2-up	CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND1-up_595 IGF1-up_3479|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LIFR-down_3977|CCND1-up_595 SOX2-up_6657|CCND2-up_894 FZD5-down_7855|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOX2-up_6657|GADD45B-down_4616 JAK1-down_3716|SERPINE1-down_5054 ID1-down_3397|THBS1-down_7057 ID1-down_3397|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 THBS1-down_7057|SERPINE1-down_5054 JAK1-down_3716|THBS1-down_7057 SOX2-up_6657
hsa04115	hsa04610	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.002	CCND1-up CFH-up|CCND1-up PLAU-up|CCND2-up PLAU-up|IGF1-up CFH-up|THBS1-down CFH-up|IGF1-up F3-down|PMAIP1-down F3-down|THBS1-down F3-down|GADD45B-down PLAU-up|GADD45B-down SERPINE1-down|SERPINB5-up MASP1-up|SERPINB5-up PLAU-up|THBS1-down PLAU-up|SERPINB5-up SERPIND1-up|THBS1-down TFPI-down	CCND1-up_595 CFH-up_3075|CCND1-up_595 PLAU-up_5328|CCND2-up_894 PLAU-up_5328|IGF1-up_3479 CFH-up_3075|THBS1-down_7057 CFH-up_3075|IGF1-up_3479 F3-down_2152|PMAIP1-down_5366 F3-down_2152|THBS1-down_7057 F3-down_2152|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 SERPINE1-down_5054|SERPINB5-up_5268 MASP1-up_5648|SERPINB5-up_5268 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|SERPINB5-up_5268 SERPIND1-up_3053|THBS1-down_7057 TFPI-down_7035
hsa04115	hsa04668	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	CCND1-up JUN-down|CCND1-up MAP3K8-down|CCND1-up SOCS3-down|CCND1-up VCAM1-up|CCND2-up CXCL2-down|CCND2-up JUN-down|CCND2-up MAP3K8-down|CCND2-up SOCS3-down|GADD45B-down CXCL2-down|IGF1-up CXCL2-down|GADD45B-down IL18R1-down|GADD45B-down JUN-down|GADD45B-down MAP3K8-down|GADD45B-down SOCS3-down|GADD45B-down VCAM1-up|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINE1-down MAP3K8-down|SERPINE1-down SOCS3-down|SERPINE1-down VCAM1-up|THBS1-down SOCS3-down|THBS1-down VCAM1-up	CCND1-up_595 JUN-down_3725|CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 SOCS3-down_9021|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL2-down_2920|CCND2-up_894 JUN-down_3725|CCND2-up_894 MAP3K8-down_1326|CCND2-up_894 SOCS3-down_9021|GADD45B-down_4616 CXCL2-down_2920|IGF1-up_3479 CXCL2-down_2920|GADD45B-down_4616 IL18R1-down_8809|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MAP3K8-down_1326|GADD45B-down_4616 SOCS3-down_9021|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINE1-down_5054 MAP3K8-down_1326|SERPINE1-down_5054 SOCS3-down_9021|SERPINE1-down_5054 VCAM1-up_7412|THBS1-down_7057 SOCS3-down_9021|THBS1-down_7057 VCAM1-up_7412
hsa04115	hsa04670	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|CCND2-up CXCL12-up|CCND2-up MMP2-up|SERPINB5-up CLDN18-down|GADD45B-down CLDN1-up|THBS1-down CLDN1-up|IGF1-up CLDN5-down|SERPINE1-down CLDN5-down|THBS1-down CLDN5-down|GADD45B-down CXCL12-up|IGF1-up CXCL12-up|SERPINB5-up CXCL12-up|SERPINE1-down CXCL12-up|THBS1-down CXCL12-up|GADD45B-down MMP2-up|GADD45B-down VCAM1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up|SERPINB5-up MMP2-up|SERPINE1-down MMP2-up|THBS1-down MMP2-up|SERPINB5-up THY1-up|SERPINE1-down THY1-up|SERPINE1-down VCAM1-up|THBS1-down THY1-up|THBS1-down VCAM1-up	CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP2-up_4313|SERPINB5-up_5268 CLDN18-down_51208|GADD45B-down_4616 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|IGF1-up_3479 CLDN5-down_7122|SERPINE1-down_5054 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|GADD45B-down_4616 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|SERPINB5-up_5268 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412|SERPINB5-up_5268 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|SERPINB5-up_5268 THY1-up_7070|SERPINE1-down_5054 THY1-up_7070|SERPINE1-down_5054 VCAM1-up_7412|THBS1-down_7057 THY1-up_7070|THBS1-down_7057 VCAM1-up_7412
hsa04115	hsa04915	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.002	CCND1-up HBEGF-down|CCND1-up HSPA1A-down|CCND1-up JUN-down|CCND1-up MMP2-up|CCND2-up HBEGF-down|CCND2-up JUN-down|CCND2-up MMP2-up|GADD45B-down HBEGF-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|IGF1-up HBEGF-down|SERPINE1-down HBEGF-down|THBS1-down HBEGF-down|IGF1-up HSPA1A-down|IGF1-up JUN-down|IGF1-up MMP2-up|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINB5-up MMP2-up|SERPINE1-down MMP2-up|THBS1-down MMP2-up	CCND1-up_595 HBEGF-down_1839|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP2-up_4313|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|IGF1-up_3479 HBEGF-down_1839|SERPINE1-down_5054 HBEGF-down_1839|THBS1-down_7057 HBEGF-down_1839|IGF1-up_3479 HSPA1A-down_3303|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINB5-up_5268 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313
hsa04115	hsa04933	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up THBS1-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up JUN-down|CCND2-up MMP2-up|CCND2-up TGFB3-up|IGF1-up COL1A1-up|THBS1-down COL1A1-up|IGF1-up COL1A2-up|THBS1-down COL1A2-up|IGF1-up COL3A1-up|THBS1-down COL3A1-up|IGF1-up F3-down|PMAIP1-down F3-down|THBS1-down F3-down|IGF1-up FIGF-down|THBS1-down FIGF-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|GADD45B-down SERPINE1-down|GADD45B-down VCAM1-up|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up TGFB3-up|IGF1-up VCAM1-up|PMAIP1-down JUN-down|SERPINB5-up JUN-down|THBS1-down JUN-down|SERPINB5-up MMP2-up|THBS1-down MMP2-up|THBS1-down TGFB3-up|THBS1-down VCAM1-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 THBS1-down_7057|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|IGF1-up_3479 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|IGF1-up_3479 F3-down_2152|PMAIP1-down_5366 F3-down_2152|THBS1-down_7057 F3-down_2152|IGF1-up_3479 FIGF-down_2277|THBS1-down_7057 FIGF-down_2277|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 SERPINE1-down_5054|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINB5-up_5268 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS1-down_7057 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412
hsa04115	hsa04974	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CCND1-up COL18A1-up|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up MME-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up MME-down|THBS1-down COL10A1-up|THBS1-down COL14A1-up|THBS1-down COL15A1-up|THBS1-down COL17A1-up|IGF1-up COL18A1-up|SERPINB5-up COL18A1-up|SERPINE1-down COL18A1-up|THBS1-down COL18A1-up|IGF1-up COL1A1-up|SERPINE1-down COL1A1-up|THBS1-down COL1A1-up|IGF1-up COL1A2-up|SERPINE1-down COL1A2-up|THBS1-down COL1A2-up|IGF1-up COL3A1-up|SERPINE1-down COL3A1-up|THBS1-down COL3A1-up|IGF1-up COL5A1-up|SERPINE1-down COL5A1-up|THBS1-down COL5A1-up|SERPINE1-down COL5A2-up|THBS1-down COL5A2-up|THBS1-down COL6A1-up|THBS1-down COL6A3-up|SERPINE1-down COL7A1-up|THBS1-down COL7A1-up|IGF1-up MME-down|IGF1-up PRSS1-up|IGF1-up SLC1A1-down|SERPINB5-up MME-down|SERPINE1-down MME-down|THBS1-down MME-down|SERPINB5-up PRSS1-up|SERPINE1-down PRSS1-up	CCND1-up_595 COL18A1-up_80781|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 MME-down_4311|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 MME-down_4311|THBS1-down_7057 COL10A1-up_1300|THBS1-down_7057 COL14A1-up_7373|THBS1-down_7057 COL15A1-up_1306|THBS1-down_7057 COL17A1-up_1308|IGF1-up_3479 COL18A1-up_80781|SERPINB5-up_5268 COL18A1-up_80781|SERPINE1-down_5054 COL18A1-up_80781|THBS1-down_7057 COL18A1-up_80781|IGF1-up_3479 COL1A1-up_1277|SERPINE1-down_5054 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|SERPINE1-down_5054 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|IGF1-up_3479 COL3A1-up_1281|SERPINE1-down_5054 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|IGF1-up_3479 COL5A1-up_1289|SERPINE1-down_5054 COL5A1-up_1289|THBS1-down_7057 COL5A1-up_1289|SERPINE1-down_5054 COL5A2-up_1290|THBS1-down_7057 COL5A2-up_1290|THBS1-down_7057 COL6A1-up_1291|THBS1-down_7057 COL6A3-up_1293|SERPINE1-down_5054 COL7A1-up_1294|THBS1-down_7057 COL7A1-up_1294|IGF1-up_3479 MME-down_4311|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SLC1A1-down_6505|SERPINB5-up_5268 MME-down_4311|SERPINE1-down_5054 MME-down_4311|THBS1-down_7057 MME-down_4311|SERPINB5-up_5268 PRSS1-up_5644|SERPINE1-down_5054 PRSS1-up_5644
hsa04115	hsa04978	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.003	CCND1-up HMOX1-down|CCND1-up TF-up|CCND2-up HMOX1-down|CCND2-up TF-up|GADD45B-down HMOX1-down|GADD45B-down MT1X-down|IGF1-up HMOX1-down|SERPINB5-up HMOX1-down|SERPINE1-down HMOX1-down|THBS1-down HMOX1-down|IGF1-up TF-up|SERPINB5-up TF-up|SERPINE1-down TF-up|THBS1-down TF-up	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|CCND2-up_894 HMOX1-down_3162|CCND2-up_894 TF-up_7018|GADD45B-down_4616 HMOX1-down_3162|GADD45B-down_4616 MT1X-down_4501|IGF1-up_3479 HMOX1-down_3162|SERPINB5-up_5268 HMOX1-down_3162|SERPINE1-down_5054 HMOX1-down_3162|THBS1-down_7057 HMOX1-down_3162|IGF1-up_3479 TF-up_7018|SERPINB5-up_5268 TF-up_7018|SERPINE1-down_5054 TF-up_7018|THBS1-down_7057 TF-up_7018
hsa04115	hsa05145	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.002	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up LDLR-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|GADD45B-down JAK1-down|IGF1-up HSPA1A-down|IGF1-up JAK1-down|IGF1-up LDLR-down|IGF1-up TGFB3-up|SERPINE1-down JAK1-down|SERPINE1-down LAMA3-down|THBS1-down LAMA3-down|SERPINE1-down LDLR-down|THBS1-down LDLR-down|SERPINE1-down TGFB3-up|THBS1-down TGFB3-up	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 LDLR-down_3949|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|GADD45B-down_4616 JAK1-down_3716|IGF1-up_3479 HSPA1A-down_3303|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 TGFB3-up_7043|SERPINE1-down_5054 JAK1-down_3716|SERPINE1-down_5054 LAMA3-down_3909|THBS1-down_7057 LAMA3-down_3909|SERPINE1-down_5054 LDLR-down_3949|THBS1-down_7057 LDLR-down_3949|SERPINE1-down_5054 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04115	hsa05146	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up LAMA3-down|CCND1-up TGFB3-up|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up TGFB3-up|IGF1-up COL1A1-up|SERPINE1-down COL1A1-up|THBS1-down COL1A1-up|IGF1-up COL1A2-up|SERPINE1-down COL1A2-up|THBS1-down COL1A2-up|IGF1-up COL3A1-up|SERPINE1-down COL3A1-up|THBS1-down COL3A1-up|GADD45B-down IL1R2-down|IGF1-up TGFB3-up|SERPINE1-down LAMA3-down|THBS1-down LAMA3-down|SERPINB5-up SERPINB3-up|SERPINE1-down SERPINB3-up|SERPINE1-down TGFB3-up|THBS1-down TGFB3-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 COL1A1-up_1277|SERPINE1-down_5054 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|SERPINE1-down_5054 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|IGF1-up_3479 COL3A1-up_1281|SERPINE1-down_5054 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|GADD45B-down_4616 IL1R2-down_7850|IGF1-up_3479 TGFB3-up_7043|SERPINE1-down_5054 LAMA3-down_3909|THBS1-down_7057 LAMA3-down_3909|SERPINB5-up_5268 SERPINB3-up_6317|SERPINE1-down_5054 SERPINB3-up_6317|SERPINE1-down_5054 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04115	hsa05152	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.002	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|IGF1-up CD74-up|THBS1-down CD74-up|GADD45B-down CLEC4E-down|GADD45B-down JAK1-down|IGF1-up JAK1-down|IGF1-up TGFB3-up|SERPINE1-down JAK1-down|SERPINE1-down TGFB3-up|THBS1-down TGFB3-up	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 CD74-up_972|THBS1-down_7057 CD74-up_972|GADD45B-down_4616 CLEC4E-down_26253|GADD45B-down_4616 JAK1-down_3716|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 TGFB3-up_7043|SERPINE1-down_5054 JAK1-down_3716|SERPINE1-down_5054 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04115	hsa05164	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up SOCS3-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|IGF1-up HSPA1A-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PRSS1-up|IGF1-up SOCS3-down|SERPINE1-down JAK1-down|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINB5-up PRSS1-up|SERPINE1-down PRSS1-up|SERPINE1-down SOCS3-down|SERPINE1-down TMPRSS4-up|THBS1-down SOCS3-down|THBS1-down TMPRSS4-up	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|IGF1-up_3479 HSPA1A-down_3303|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SOCS3-down_9021|SERPINE1-down_5054 JAK1-down_3716|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINB5-up_5268 PRSS1-up_5644|SERPINE1-down_5054 PRSS1-up_5644|SERPINE1-down_5054 SOCS3-down_9021|SERPINE1-down_5054 TMPRSS4-up_56649|THBS1-down_7057 SOCS3-down_9021|THBS1-down_7057 TMPRSS4-up_56649
hsa04115	hsa05166	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up SERPINE1-down|CCND1-up THBS1-down|CCND2-up GADD45B-down|CCND2-up PMAIP1-down|CCND2-up SERPINE1-down|CCND2-up THBS1-down|GADD45B-down IL1R2-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down MYB-up|GADD45B-down VCAM1-up|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up MYB-up|IGF1-up PDGFRA-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|SERPINE1-down JAK1-down|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINB5-up MYB-up|SERPINE1-down MYB-up|THBS1-down MYB-up|THBS1-down PDGFRA-down|SERPINE1-down TGFB3-up|SERPINE1-down VCAM1-up|THBS1-down TGFB3-up|THBS1-down VCAM1-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 SERPINE1-down_5054|CCND1-up_595 THBS1-down_7057|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 PMAIP1-down_5366|CCND2-up_894 SERPINE1-down_5054|CCND2-up_894 THBS1-down_7057|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MYB-up_4602|GADD45B-down_4616 VCAM1-up_7412|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MYB-up_4602|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|SERPINE1-down_5054 JAK1-down_3716|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINB5-up_5268 MYB-up_4602|SERPINE1-down_5054 MYB-up_4602|THBS1-down_7057 MYB-up_4602|THBS1-down_7057 PDGFRA-down_5156|SERPINE1-down_5054 TGFB3-up_7043|SERPINE1-down_5054 VCAM1-up_7412|THBS1-down_7057 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412
hsa04115	hsa05168	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up SOCS3-down|IGF1-up CD74-up|THBS1-down CD74-up|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down SOCS3-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|SERPINE1-down JAK1-down|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINE1-down SOCS3-down|THBS1-down SOCS3-down	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|IGF1-up_3479 CD74-up_972|THBS1-down_7057 CD74-up_972|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|SERPINE1-down_5054 JAK1-down_3716|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINE1-down_5054 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021
hsa04115	hsa05200	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up SERPINE1-down|CCND1-up THBS1-down|CCND2-up CXCL12-up|CCND2-up FZD5-down|CCND2-up HHIP-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up PDGFRA-down|CCND2-up TCF7L2-up|CCND2-up TGFB3-up|CCND2-up ZBTB16-down|GADD45B-down CXCL12-up|SERPINB5-up CXCL12-up|SERPINE1-down CXCL12-up|THBS1-down CXCL12-up|GADD45B-down DAPK2-down|SERPINE1-down EDNRB-down|THBS1-down EDNRB-down|SERPINE1-down FIGF-down|THBS1-down FIGF-down|GADD45B-down JAK1-down|GADD45B-down JUN-down|GADD45B-down MMP2-up|IGF1-up SERPINE1-down|IGF1-up THBS1-down|SERPINE1-down JAK1-down|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINE1-down LAMA3-down|THBS1-down LAMA3-down|SERPINB5-up MMP1-up|SERPINE1-down MMP1-up|THBS1-down MMP1-up|SERPINB5-up MMP2-up|SERPINE1-down MMP2-up|THBS1-down MMP2-up|THBS1-down PDGFRA-down|PMAIP1-down TCF7L2-up|SERPINE1-down TGFB3-up|THBS1-down TGFB3-up|THBS1-down ZBTB16-down	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 SERPINE1-down_5054|CCND1-up_595 THBS1-down_7057|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HHIP-down_64399|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 TCF7L2-up_6934|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 ZBTB16-down_7704|GADD45B-down_4616 CXCL12-up_6387|SERPINB5-up_5268 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|GADD45B-down_4616 DAPK2-down_23604|SERPINE1-down_5054 EDNRB-down_1910|THBS1-down_7057 EDNRB-down_1910|SERPINE1-down_5054 FIGF-down_2277|THBS1-down_7057 FIGF-down_2277|GADD45B-down_4616 JAK1-down_3716|GADD45B-down_4616 JUN-down_3725|GADD45B-down_4616 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 THBS1-down_7057|SERPINE1-down_5054 JAK1-down_3716|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINE1-down_5054 LAMA3-down_3909|THBS1-down_7057 LAMA3-down_3909|SERPINB5-up_5268 MMP1-up_4312|SERPINE1-down_5054 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|SERPINB5-up_5268 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS1-down_7057 PDGFRA-down_5156|PMAIP1-down_5366 TCF7L2-up_6934|SERPINE1-down_5054 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS1-down_7057 ZBTB16-down_7704
hsa04115	hsa05202	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.003	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up GADD45B-down|CCND2-up PMAIP1-down|CCND2-up SERPINE1-down|CCND2-up THBS1-down|SERPINB5-up FLT1-down|SERPINE1-down FLT1-down|THBS1-down FLT1-down|GADD45B-down IL1R2-down|GADD45B-down NFKBIZ-down|GADD45B-down PLAU-up|IGF1-up SERPINE1-down|IGF1-up THBS1-down|SERPINB5-up PLAU-up|SERPINE1-down PLAU-up|THBS1-down PLAU-up|SERPINE1-down PROM1-up|THBS1-down PROM1-up|THBS1-down ZBTB16-down	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 PMAIP1-down_5366|CCND2-up_894 SERPINE1-down_5054|CCND2-up_894 THBS1-down_7057|SERPINB5-up_5268 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|GADD45B-down_4616 IL1R2-down_7850|GADD45B-down_4616 NFKBIZ-down_64332|GADD45B-down_4616 PLAU-up_5328|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 THBS1-down_7057|SERPINB5-up_5268 PLAU-up_5328|SERPINE1-down_5054 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|SERPINE1-down_5054 PROM1-up_8842|THBS1-down_7057 PROM1-up_8842|THBS1-down_7057 ZBTB16-down_7704
hsa04115	hsa05205	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.001	SERPINB5-up CAV2-down|SERPINE1-down CAV2-down|CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up SERPINE1-down|CCND2-up FZD5-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down PLAU-up|GADD45B-down THBS1-down|SERPINE1-down HBEGF-down|IGF1-up SERPINE1-down|SERPINB5-up MMP2-up|SERPINE1-down MMP2-up|SERPINB5-up PLAU-up|SERPINE1-down PLAU-up|SERPINE1-down THBS1-down	SERPINB5-up_5268 CAV2-down_858|SERPINE1-down_5054 CAV2-down_858|CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|SERPINE1-down_5054 HBEGF-down_1839|IGF1-up_3479 SERPINE1-down_5054|SERPINB5-up_5268 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|SERPINB5-up_5268 PLAU-up_5328|SERPINE1-down_5054 PLAU-up_5328|SERPINE1-down_5054 THBS1-down_7057
hsa04115	hsa05206	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.014	CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up SERPINE1-down|CCND2-up GADD45B-down|CCND2-up PMAIP1-down|CCND2-up SERPINE1-down|IGF1-up CYP24A1-up|GADD45B-down HMOX1-down|GADD45B-down MCL1-down|GADD45B-down PLAU-up|GADD45B-down THBS1-down|IGF1-up HMOX1-down|SERPINE1-down HMOX1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up TNC-up|SERPINE1-down IRS2-down|PMAIP1-down MCL1-down|SERPINE1-down MCL1-down|SERPINE1-down MMP16-up|SERPINE1-down PLAU-up|SERPINB5-up SERPINE1-down|SERPINE1-down THBS1-down|SERPINE1-down TNC-up|SERPINE1-down TP63-up	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 GADD45B-down_4616|CCND2-up_894 PMAIP1-down_5366|CCND2-up_894 SERPINE1-down_5054|IGF1-up_3479 CYP24A1-up_1591|GADD45B-down_4616 HMOX1-down_3162|GADD45B-down_4616 MCL1-down_4170|GADD45B-down_4616 PLAU-up_5328|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 HMOX1-down_3162|SERPINE1-down_5054 HMOX1-down_3162|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 TNC-up_3371|SERPINE1-down_5054 IRS2-down_8660|PMAIP1-down_5366 MCL1-down_4170|SERPINE1-down_5054 MCL1-down_4170|SERPINE1-down_5054 MMP16-up_4325|SERPINE1-down_5054 PLAU-up_5328|SERPINB5-up_5268 SERPINE1-down_5054|SERPINE1-down_5054 THBS1-down_7057|SERPINE1-down_5054 TNC-up_3371|SERPINE1-down_5054 TP63-up_8626
hsa04115	hsa05219	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.001	CCND1-up GADD45B-down|CCND1-up PMAIP1-down|CCND1-up SERPINE1-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|GADD45B-down DAPK2-down|GADD45B-down HBEGF-down|GADD45B-down MMP2-up|GADD45B-down THBS1-down|IGF1-up HBEGF-down|SERPINE1-down HBEGF-down|IGF1-up MMP1-up|IGF1-up MMP2-up|SERPINB5-up MMP1-up|SERPINE1-down MMP1-up|SERPINB5-up MMP2-up|SERPINE1-down MMP2-up|SERPINE1-down THBS1-down	CCND1-up_595 GADD45B-down_4616|CCND1-up_595 PMAIP1-down_5366|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|GADD45B-down_4616 DAPK2-down_23604|GADD45B-down_4616 HBEGF-down_1839|GADD45B-down_4616 MMP2-up_4313|GADD45B-down_4616 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|SERPINE1-down_5054 HBEGF-down_1839|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|SERPINB5-up_5268 MMP1-up_4312|SERPINE1-down_5054 MMP1-up_4312|SERPINB5-up_5268 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|SERPINE1-down_5054 THBS1-down_7057
hsa04115	hsa05323	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up FLT1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|IGF1-up CTSK-up|SERPINB5-up CTSK-up|SERPINE1-down CTSK-up|THBS1-down CTSK-up|GADD45B-down CXCL12-up|IGF1-up CXCL12-up|SERPINB5-up CXCL12-up|SERPINE1-down CXCL12-up|THBS1-down CXCL12-up|IGF1-up FLT1-down|SERPINB5-up FLT1-down|SERPINE1-down FLT1-down|THBS1-down FLT1-down|GADD45B-down JUN-down|IGF1-up JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|PMAIP1-down JUN-down|SERPINB5-up JUN-down|SERPINE1-down JUN-down|THBS1-down JUN-down|SERPINB5-up MMP1-up|SERPINE1-down MMP1-up|THBS1-down MMP1-up|SERPINE1-down TGFB3-up|THBS1-down TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 CTSK-up_1513|SERPINB5-up_5268 CTSK-up_1513|SERPINE1-down_5054 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|GADD45B-down_4616 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|SERPINB5-up_5268 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|IGF1-up_3479 FLT1-down_2321|SERPINB5-up_5268 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|GADD45B-down_4616 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|PMAIP1-down_5366 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|THBS1-down_7057 JUN-down_3725|SERPINB5-up_5268 MMP1-up_4312|SERPINE1-down_5054 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|SERPINE1-down_5054 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04115	hsa05410	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.01	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|IGF1-up SERPINE1-down|IGF1-up THBS1-down|SERPINB5-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|SERPINE1-down TGFB3-up|THBS1-down TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 THBS1-down_7057|SERPINB5-up_5268 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|SERPINE1-down_5054 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa04115	hsa05412	p53 signaling pathway - Homo sapiens (human)	GADD45B,PMAIP1,SERPINE1,THBS1,CCND1,CCND2,IGF1,SERPINB5,ZMAT3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.002	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|IGF1-up CDH2-up|SERPINB5-up CDH2-up|SERPINE1-down CDH2-up|THBS1-down CDH2-up|IGF1-up TCF7L2-up|SERPINB5-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|PMAIP1-down TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|IGF1-up_3479 CDH2-up_1000|SERPINB5-up_5268 CDH2-up_1000|SERPINE1-down_5054 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|IGF1-up_3479 TCF7L2-up_6934|SERPINB5-up_5268 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|PMAIP1-down_5366 TCF7L2-up_6934
hsa04144	hsa04152	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	0.044	ARRB1-down CCND1-up|ARRB1-down IGF1-up|CAV2-down CCND1-up|CAV2-down FASN-down|CXCR2-down CCND1-up|FLT1-down CCND1-up|HSPA1A-down CCND1-up|LDLR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CXCR2-down HMGCR-down|CXCR2-down IGF1-up|FLT1-down FASN-down|LDLR-down FASN-down|FLT1-down HMGCR-down|FLT1-down IGF1-up|FLT1-down IRS2-down|LDLR-down HMGCR-down|HSPA1A-down IGF1-up|HSPA1A-down PFKFB2-down|HSPA1B-down PFKFB2-down|LDLR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|LDLR-down IRS2-down|PDGFRA-down IRS2-down|LDLR-down SCD-down	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 IGF1-up_3479|CAV2-down_858 CCND1-up_595|CAV2-down_858 FASN-down_2194|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|LDLR-down_3949 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCR2-down_3579 HMGCR-down_3156|CXCR2-down_3579 IGF1-up_3479|FLT1-down_2321 FASN-down_2194|LDLR-down_3949 FASN-down_2194|FLT1-down_2321 HMGCR-down_3156|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 IRS2-down_8660|LDLR-down_3949 HMGCR-down_3156|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 PFKFB2-down_5208|HSPA1B-down_3304 PFKFB2-down_5208|LDLR-down_3949 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|LDLR-down_3949 IRS2-down_8660|PDGFRA-down_5156 IRS2-down_8660|LDLR-down_3949 SCD-down_6319
hsa04144	hsa04310	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0.008	ARRB1-down CCND1-up|ARRB1-down FZD5-down|ARRB1-down JUN-down|ARRB1-down SFRP2-up|ARRB1-down SFRP4-up|CAV2-down CCND1-up|CAV2-down JUN-down|CXCR2-down CCND1-up|FLT1-down CCND1-up|HSPA1A-down CCND1-up|LDLR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|FLT1-down CCND2-up|PDGFRA-down CCND2-up|TGFB3-up CCND2-up|CXCR2-down JUN-down|CXCR2-down MMP7-up|DNM1-up JUN-down|FLT1-down FZD5-down|FLT1-down JUN-down|FLT1-down MMP7-up|FLT1-down SERPINF1-up|FLT1-down SFRP2-up|PDGFRA-down FZD5-down|HSPA1A-down JUN-down|HSPA1B-down JUN-down|LDLR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|LDLR-down TCF7L2-up|PDGFRA-down SFRP2-up|PDGFRA-down SFRP4-up|PDGFRA-down TCF7L2-up|TGFB3-up SFRP2-up|TGFB3-up SFRP4-up|TGFB3-up TCF7L2-up	ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 SFRP2-up_6423|ARRB1-down_408 SFRP4-up_6424|CAV2-down_858 CCND1-up_595|CAV2-down_858 JUN-down_3725|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|LDLR-down_3949 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|FLT1-down_2321 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP7-up_4316|DNM1-up_1759 JUN-down_3725|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP7-up_4316|FLT1-down_2321 SERPINF1-up_5176|FLT1-down_2321 SFRP2-up_6423|PDGFRA-down_5156 FZD5-down_7855|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|LDLR-down_3949 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|LDLR-down_3949 TCF7L2-up_6934|PDGFRA-down_5156 SFRP2-up_6423|PDGFRA-down_5156 SFRP4-up_6424|PDGFRA-down_5156 TCF7L2-up_6934|TGFB3-up_7043 SFRP2-up_6423|TGFB3-up_7043 SFRP4-up_6424|TGFB3-up_7043 TCF7L2-up_6934
hsa04144	hsa04360	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0.017	ARRB1-down CXCL12-up|ARRB1-down NTN1-up|FLT1-down BOC-up|CXCR2-down CXCL12-up|DNM1-up CXCL12-up|FLT1-down CXCL12-up|LDLR-down CXCL12-up|PDGFRA-down CXCL12-up|TGFB3-up CXCL12-up|DNM1-up EPHA3-up|DNM1-up RND1-down|HSPA1A-down EPHA3-up|HSPA1B-down EPHA3-up|PDGFRA-down EPHA3-up|FLT1-down NTN1-up|FLT1-down RND1-down|FLT1-down ROBO2-up|FLT1-down SEMA3E-down|PDGFRA-down NTN1-up|TGFB3-up NTN1-up|PDGFRA-down RND1-down|PDGFRA-down ROBO2-up|PSD3-up RND1-down	ARRB1-down_408 CXCL12-up_6387|ARRB1-down_408 NTN1-up_9423|FLT1-down_2321 BOC-up_91653|CXCR2-down_3579 CXCL12-up_6387|DNM1-up_1759 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|LDLR-down_3949 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|DNM1-up_1759 EPHA3-up_2042|DNM1-up_1759 RND1-down_27289|HSPA1A-down_3303 EPHA3-up_2042|HSPA1B-down_3304 EPHA3-up_2042|PDGFRA-down_5156 EPHA3-up_2042|FLT1-down_2321 NTN1-up_9423|FLT1-down_2321 RND1-down_27289|FLT1-down_2321 ROBO2-up_6092|FLT1-down_2321 SEMA3E-down_9723|PDGFRA-down_5156 NTN1-up_9423|TGFB3-up_7043 NTN1-up_9423|PDGFRA-down_5156 RND1-down_27289|PDGFRA-down_5156 ROBO2-up_6092|PSD3-up_23362 RND1-down_27289
hsa04144	hsa04512	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	ADRB1-down SPP1-up|ARRB1-down SPP1-up|CAV2-down ITGB4-up|CAV2-down ITGB8-up|CAV2-down LAMA3-down|CXCR2-down COL1A1-up|FLT1-down COL1A1-up|HSPA1A-down COL1A1-up|LDLR-down COL1A1-up|PDGFRA-down COL1A1-up|TGFB3-up COL1A1-up|FLT1-down COL1A2-up|PDGFRA-down COL1A2-up|TGFB3-up COL1A2-up|PDGFRA-down COL6A1-up|TGFB3-up COL6A1-up|PDGFRA-down COL6A3-up|TGFB3-up COL6A3-up|TGFB3-up COMP-up|CXCR2-down SPP1-up|CXCR2-down THBS1-down|FLT1-down ITGB4-up|FLT1-down SPP1-up|FLT1-down THBS1-down|FLT1-down THBS2-up|FLT1-down TNC-up|PDGFRA-down ITGB4-up|TGFB3-up ITGB8-up|LDLR-down THBS1-down|LDLR-down TNC-up|PDGFRA-down SPP1-up|PDGFRA-down THBS1-down|PDGFRA-down TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	ADRB1-down_153 SPP1-up_6696|ARRB1-down_408 SPP1-up_6696|CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CAV2-down_858 LAMA3-down_3909|CXCR2-down_3579 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|HSPA1A-down_3303 COL1A1-up_1277|LDLR-down_3949 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|FLT1-down_2321 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|PDGFRA-down_5156 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|TGFB3-up_7043 COMP-up_1311|CXCR2-down_3579 SPP1-up_6696|CXCR2-down_3579 THBS1-down_7057|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 SPP1-up_6696|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 THBS2-up_7058|FLT1-down_2321 TNC-up_3371|PDGFRA-down_5156 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|LDLR-down_3949 THBS1-down_7057|LDLR-down_3949 TNC-up_3371|PDGFRA-down_5156 SPP1-up_6696|PDGFRA-down_5156 THBS1-down_7057|PDGFRA-down_5156 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04144	hsa04514	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0.003	ARRB1-down CD274-down|CAV2-down CDH2-up|CAV2-down ITGB8-up|PDGFRA-down CD274-down|FLT1-down CDH2-up|PDGFRA-down CDH2-up|TGFB3-up CDH2-up|LDLR-down CLDN1-up|FLT1-down CLDN5-down|CXCR2-down NCAM1-up|CXCR2-down SELL-down|CXCR2-down VCAM1-up|DNM1-up NCAM1-up|DNM1-up SELL-down|DNM1-up VCAM1-up|FLT1-down NCAM1-up|FLT1-down SELL-down|FLT1-down VCAM1-up|TGFB3-up ITGB8-up|LDLR-down NCAM1-up|LDLR-down VCAM1-up|PDGFRA-down NCAM1-up|TGFB3-up NCAM1-up|PDGFRA-down VCAM1-up|TGFB3-up VCAM1-up	ARRB1-down_408 CD274-down_29126|CAV2-down_858 CDH2-up_1000|CAV2-down_858 ITGB8-up_3696|PDGFRA-down_5156 CD274-down_29126|FLT1-down_2321 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|LDLR-down_3949 CLDN1-up_9076|FLT1-down_2321 CLDN5-down_7122|CXCR2-down_3579 NCAM1-up_4684|CXCR2-down_3579 SELL-down_6402|CXCR2-down_3579 VCAM1-up_7412|DNM1-up_1759 NCAM1-up_4684|DNM1-up_1759 SELL-down_6402|DNM1-up_1759 VCAM1-up_7412|FLT1-down_2321 NCAM1-up_4684|FLT1-down_2321 SELL-down_6402|FLT1-down_2321 VCAM1-up_7412|TGFB3-up_7043 ITGB8-up_3696|LDLR-down_3949 NCAM1-up_4684|LDLR-down_3949 VCAM1-up_7412|PDGFRA-down_5156 NCAM1-up_4684|TGFB3-up_7043 NCAM1-up_4684|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04144	hsa04550	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.025	ARRB1-down FZD5-down|ARRB1-down IGF1-up|ARRB1-down JAK1-down|CXCR2-down IGF1-up|DNM1-up JAK1-down|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down IGF1-up|FLT1-down JAK1-down|FLT1-down SOX2-up|PDGFRA-down FZD5-down|HSPA1A-down IGF1-up|HSPA1A-down JAK1-down|HSPA1B-down JAK1-down|PDGFRA-down ID1-down|TGFB3-up ID1-down|LDLR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|PDGFRA-down JAK1-down|PDGFRA-down SOX2-up	ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 IGF1-up_3479|ARRB1-down_408 JAK1-down_3716|CXCR2-down_3579 IGF1-up_3479|DNM1-up_1759 JAK1-down_3716|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 SOX2-up_6657|PDGFRA-down_5156 FZD5-down_7855|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 JAK1-down_3716|HSPA1B-down_3304 JAK1-down_3716|PDGFRA-down_5156 ID1-down_3397|TGFB3-up_7043 ID1-down_3397|LDLR-down_3949 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 SOX2-up_6657
hsa04144	hsa04610	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0	ADRB1-down SERPINE1-down|ADRB1-down TFPI-down|CAV2-down F3-down|CAV2-down SERPINE1-down|FLT1-down CFH-up|LDLR-down CFH-up|PDGFRA-down CFH-up|CXCR2-down F3-down|CXCR2-down SERPINE1-down|DNM1-up SERPINE1-down|FLT1-down F3-down|HSPA1A-down F3-down|PDGFRA-down F3-down|FLT1-down PLAU-up|FLT1-down SERPINE1-down|FLT1-down TFPI-down|LDLR-down SERPINE1-down|LDLR-down TFPI-down|PDGFRA-down PLAU-up|TGFB3-up PLAU-up|TGFB3-up SERPINE1-down	ADRB1-down_153 SERPINE1-down_5054|ADRB1-down_153 TFPI-down_7035|CAV2-down_858 F3-down_2152|CAV2-down_858 SERPINE1-down_5054|FLT1-down_2321 CFH-up_3075|LDLR-down_3949 CFH-up_3075|PDGFRA-down_5156 CFH-up_3075|CXCR2-down_3579 F3-down_2152|CXCR2-down_3579 SERPINE1-down_5054|DNM1-up_1759 SERPINE1-down_5054|FLT1-down_2321 F3-down_2152|HSPA1A-down_3303 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TFPI-down_7035|LDLR-down_3949 SERPINE1-down_5054|LDLR-down_3949 TFPI-down_7035|PDGFRA-down_5156 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SERPINE1-down_5054
hsa04144	hsa04668	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.002	ADRB1-down MAP3K8-down|ARRB1-down CXCL2-down|ARRB1-down JUN-down|CAV2-down JUN-down|CXCR2-down CXCL2-down|HSPA1A-down CXCL2-down|LDLR-down CXCL2-down|CXCR2-down CXCL3-down|CXCR2-down JUN-down|CXCR2-down SOCS3-down|CXCR2-down VCAM1-up|DNM1-up JUN-down|DNM1-up MAP3K8-down|DNM1-up VCAM1-up|FLT1-down JUN-down|FLT1-down SOCS3-down|FLT1-down VCAM1-up|HSPA1A-down JUN-down|HSPA1B-down JUN-down|LDLR-down JUN-down|PDGFRA-down JUN-down|TGFB3-up JUN-down|LDLR-down MAP3K8-down|LDLR-down SOCS3-down|LDLR-down VCAM1-up|PDGFRA-down MAP3K8-down|PDGFRA-down SOCS3-down|PDGFRA-down VCAM1-up|TGFB3-up VCAM1-up	ADRB1-down_153 MAP3K8-down_1326|ARRB1-down_408 CXCL2-down_2920|ARRB1-down_408 JUN-down_3725|CAV2-down_858 JUN-down_3725|CXCR2-down_3579 CXCL2-down_2920|HSPA1A-down_3303 CXCL2-down_2920|LDLR-down_3949 CXCL2-down_2920|CXCR2-down_3579 CXCL3-down_2921|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 SOCS3-down_9021|CXCR2-down_3579 VCAM1-up_7412|DNM1-up_1759 JUN-down_3725|DNM1-up_1759 MAP3K8-down_1326|DNM1-up_1759 VCAM1-up_7412|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|FLT1-down_2321 VCAM1-up_7412|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|LDLR-down_3949 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|LDLR-down_3949 MAP3K8-down_1326|LDLR-down_3949 SOCS3-down_9021|LDLR-down_3949 VCAM1-up_7412|PDGFRA-down_5156 MAP3K8-down_1326|PDGFRA-down_5156 SOCS3-down_9021|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04144	hsa04670	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0.001	ARRB1-down CXCL12-up|CAV2-down MMP2-up|LDLR-down CLDN1-up|FLT1-down CLDN5-down|CXCR2-down CXCL12-up|DNM1-up CXCL12-up|FLT1-down CXCL12-up|LDLR-down CXCL12-up|PDGFRA-down CXCL12-up|TGFB3-up CXCL12-up|CXCR2-down MMP2-up|CXCR2-down VCAM1-up|DNM1-up THY1-up|DNM1-up VCAM1-up|FLT1-down MMP2-up|FLT1-down VCAM1-up|LDLR-down MMP2-up|LDLR-down VCAM1-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down VCAM1-up|TGFB3-up THY1-up|TGFB3-up VCAM1-up	ARRB1-down_408 CXCL12-up_6387|CAV2-down_858 MMP2-up_4313|LDLR-down_3949 CLDN1-up_9076|FLT1-down_2321 CLDN5-down_7122|CXCR2-down_3579 CXCL12-up_6387|DNM1-up_1759 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|LDLR-down_3949 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 VCAM1-up_7412|DNM1-up_1759 THY1-up_7070|DNM1-up_1759 VCAM1-up_7412|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 VCAM1-up_7412|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 VCAM1-up_7412|TGFB3-up_7043 THY1-up_7070|TGFB3-up_7043 VCAM1-up_7412
hsa04144	hsa04933	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	ADRB1-down SERPINE1-down|ARRB1-down CCND1-up|ARRB1-down JUN-down|ARRB1-down TGFB3-up|CAV2-down CCND1-up|CAV2-down F3-down|CAV2-down JUN-down|CAV2-down MMP2-up|CAV2-down SERPINE1-down|CXCR2-down CCND1-up|FLT1-down CCND1-up|HSPA1A-down CCND1-up|LDLR-down CCND1-up|PDGFRA-down CCND1-up|CXCR2-down COL1A1-up|FLT1-down COL1A1-up|HSPA1A-down COL1A1-up|LDLR-down COL1A1-up|PDGFRA-down COL1A1-up|FLT1-down COL1A2-up|PDGFRA-down COL1A2-up|FLT1-down COL3A1-up|HSPA1A-down COL3A1-up|PDGFRA-down COL3A1-up|CXCR2-down F3-down|CXCR2-down JUN-down|CXCR2-down MMP2-up|CXCR2-down SERPINE1-down|CXCR2-down VCAM1-up|DNM1-up JUN-down|DNM1-up SERPINE1-down|DNM1-up VCAM1-up|FLT1-down F3-down|HSPA1A-down F3-down|PDGFRA-down F3-down|FLT1-down FIGF-down|PDGFRA-down FIGF-down|FLT1-down JUN-down|FLT1-down MMP2-up|FLT1-down SERPINE1-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|HSPA1A-down JUN-down|HSPA1B-down JUN-down|LDLR-down JUN-down|PDGFRA-down JUN-down|LDLR-down MMP2-up|LDLR-down SERPINE1-down|LDLR-down VCAM1-up|PDGFRA-down MMP2-up|PDGFRA-down TGFB3-up|PDGFRA-down VCAM1-up	ADRB1-down_153 SERPINE1-down_5054|ARRB1-down_408 CCND1-up_595|ARRB1-down_408 JUN-down_3725|ARRB1-down_408 TGFB3-up_7043|CAV2-down_858 CCND1-up_595|CAV2-down_858 F3-down_2152|CAV2-down_858 JUN-down_3725|CAV2-down_858 MMP2-up_4313|CAV2-down_858 SERPINE1-down_5054|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|LDLR-down_3949 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|CXCR2-down_3579 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|HSPA1A-down_3303 COL1A1-up_1277|LDLR-down_3949 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|FLT1-down_2321 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|HSPA1A-down_3303 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|CXCR2-down_3579 F3-down_2152|CXCR2-down_3579 JUN-down_3725|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 SERPINE1-down_5054|CXCR2-down_3579 VCAM1-up_7412|DNM1-up_1759 JUN-down_3725|DNM1-up_1759 SERPINE1-down_5054|DNM1-up_1759 VCAM1-up_7412|FLT1-down_2321 F3-down_2152|HSPA1A-down_3303 F3-down_2152|PDGFRA-down_5156 F3-down_2152|FLT1-down_2321 FIGF-down_2277|PDGFRA-down_5156 FIGF-down_2277|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|LDLR-down_3949 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 SERPINE1-down_5054|LDLR-down_3949 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 VCAM1-up_7412
hsa04144	hsa04974	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	ADRB1-down MME-down|CAV2-down COL18A1-up|TGFB3-up COL10A1-up|TGFB3-up COL14A1-up|CXCR2-down COL18A1-up|FLT1-down COL18A1-up|LDLR-down COL18A1-up|TGFB3-up COL18A1-up|CXCR2-down COL1A1-up|FLT1-down COL1A1-up|HSPA1A-down COL1A1-up|LDLR-down COL1A1-up|PDGFRA-down COL1A1-up|TGFB3-up COL1A1-up|FLT1-down COL1A2-up|PDGFRA-down COL1A2-up|TGFB3-up COL1A2-up|FLT1-down COL3A1-up|HSPA1A-down COL3A1-up|PDGFRA-down COL3A1-up|TGFB3-up COL3A1-up|FLT1-down COL5A1-up|PDGFRA-down COL5A1-up|TGFB3-up COL5A1-up|LDLR-down COL5A2-up|TGFB3-up COL5A2-up|PDGFRA-down COL6A1-up|TGFB3-up COL6A1-up|PDGFRA-down COL6A3-up|TGFB3-up COL6A3-up|DNM1-up MME-down|FLT1-down MME-down|HSPA1A-down MME-down|HSPA1B-down MME-down|LDLR-down MME-down|PDGFRA-down MME-down	ADRB1-down_153 MME-down_4311|CAV2-down_858 COL18A1-up_80781|TGFB3-up_7043 COL10A1-up_1300|TGFB3-up_7043 COL14A1-up_7373|CXCR2-down_3579 COL18A1-up_80781|FLT1-down_2321 COL18A1-up_80781|LDLR-down_3949 COL18A1-up_80781|TGFB3-up_7043 COL18A1-up_80781|CXCR2-down_3579 COL1A1-up_1277|FLT1-down_2321 COL1A1-up_1277|HSPA1A-down_3303 COL1A1-up_1277|LDLR-down_3949 COL1A1-up_1277|PDGFRA-down_5156 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|FLT1-down_2321 COL1A2-up_1278|PDGFRA-down_5156 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|FLT1-down_2321 COL3A1-up_1281|HSPA1A-down_3303 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|TGFB3-up_7043 COL3A1-up_1281|FLT1-down_2321 COL5A1-up_1289|PDGFRA-down_5156 COL5A1-up_1289|TGFB3-up_7043 COL5A1-up_1289|LDLR-down_3949 COL5A2-up_1290|TGFB3-up_7043 COL5A2-up_1290|PDGFRA-down_5156 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|PDGFRA-down_5156 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|DNM1-up_1759 MME-down_4311|FLT1-down_2321 MME-down_4311|HSPA1A-down_3303 MME-down_4311|HSPA1B-down_3304 MME-down_4311|LDLR-down_3949 MME-down_4311|PDGFRA-down_5156 MME-down_4311
hsa04144	hsa04978	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.009	ARRB1-down TF-up|CAV2-down HMOX1-down|CAV2-down TF-up|CXCR2-down HMOX1-down|CXCR2-down TF-up|DNM1-up TF-up|FLT1-down HMOX1-down|FLT1-down TF-up|HSPA1A-down HMOX1-down|HSPA1B-down HMOX1-down|LDLR-down HMOX1-down|PDGFRA-down HMOX1-down|HSPA1A-down MT2A-down|LDLR-down TF-up|PDGFRA-down TF-up|TGFB3-up TF-up	ARRB1-down_408 TF-up_7018|CAV2-down_858 HMOX1-down_3162|CAV2-down_858 TF-up_7018|CXCR2-down_3579 HMOX1-down_3162|CXCR2-down_3579 TF-up_7018|DNM1-up_1759 TF-up_7018|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 TF-up_7018|HSPA1A-down_3303 HMOX1-down_3162|HSPA1B-down_3304 HMOX1-down_3162|LDLR-down_3949 HMOX1-down_3162|PDGFRA-down_5156 HMOX1-down_3162|HSPA1A-down_3303 MT2A-down_4502|LDLR-down_3949 TF-up_7018|PDGFRA-down_5156 TF-up_7018|TGFB3-up_7043 TF-up_7018
hsa04144	hsa05205	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.015	FLT1-down ANK2-up|PDGFRA-down ANK2-up|ARRB1-down CCND1-up|ARRB1-down FLNC-up|ARRB1-down FZD5-down|ARRB1-down IGF1-up|CXCR2-down CCND1-up|FLT1-down CCND1-up|HSPA1A-down CCND1-up|LDLR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CXCR2-down IGF1-up|CXCR2-down MMP2-up|CXCR2-down THBS1-down|FLT1-down FZD5-down|FLT1-down HBEGF-down|FLT1-down IGF1-up|FLT1-down MMP2-up|FLT1-down PLAU-up|FLT1-down THBS1-down|PDGFRA-down FZD5-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|HSPA1A-down IGF1-up|LDLR-down IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|LDLR-down MMP2-up|LDLR-down THBS1-down|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down PLAU-up|PDGFRA-down THBS1-down|TGFB3-up PLAU-up|TGFB3-up THBS1-down	FLT1-down_2321 ANK2-up_287|PDGFRA-down_5156 ANK2-up_287|ARRB1-down_408 CCND1-up_595|ARRB1-down_408 FLNC-up_2318|ARRB1-down_408 FZD5-down_7855|ARRB1-down_408 IGF1-up_3479|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|LDLR-down_3949 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCR2-down_3579 IGF1-up_3479|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 THBS1-down_7057|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 THBS1-down_7057|PDGFRA-down_5156 FZD5-down_7855|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|HSPA1A-down_3303 IGF1-up_3479|LDLR-down_3949 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 THBS1-down_7057|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057
hsa04144	hsa05206	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.006	ADRB1-down MCL1-down|ADRB1-down TP63-up|ARRB1-down CCND1-up|ARRB1-down PDGFRA-down|CAV2-down CCND1-up|CAV2-down HMOX1-down|CAV2-down SERPINB5-up|CXCR2-down CCND1-up|FLT1-down CCND1-up|HSPA1A-down CCND1-up|LDLR-down CCND1-up|TGFB3-up CCND1-up|FLT1-down CCND2-up|TGFB3-up CCND2-up|CXCR2-down CYP24A1-up|CXCR2-down HMOX1-down|CXCR2-down MCL1-down|CXCR2-down THBS1-down|LDLR-down CYP24A1-up|DNM1-up MCL1-down|FLT1-down HMOX1-down|FLT1-down IRS2-down|FLT1-down MCL1-down|FLT1-down MMP16-up|FLT1-down PDGFRA-down|FLT1-down PLAU-up|FLT1-down SERPINB5-up|FLT1-down THBS1-down|FLT1-down TNC-up|FLT1-down TP63-up|HSPA1A-down HMOX1-down|HSPA1B-down HMOX1-down|LDLR-down HMOX1-down|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|LDLR-down IRS2-down|LDLR-down THBS1-down|LDLR-down TNC-up|TGFB3-up PLAU-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	ADRB1-down_153 MCL1-down_4170|ADRB1-down_153 TP63-up_8626|ARRB1-down_408 CCND1-up_595|ARRB1-down_408 PDGFRA-down_5156|CAV2-down_858 CCND1-up_595|CAV2-down_858 HMOX1-down_3162|CAV2-down_858 SERPINB5-up_5268|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|LDLR-down_3949 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|FLT1-down_2321 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CXCR2-down_3579 CYP24A1-up_1591|CXCR2-down_3579 HMOX1-down_3162|CXCR2-down_3579 MCL1-down_4170|CXCR2-down_3579 THBS1-down_7057|LDLR-down_3949 CYP24A1-up_1591|DNM1-up_1759 MCL1-down_4170|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 MMP16-up_4325|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 TNC-up_3371|FLT1-down_2321 TP63-up_8626|HSPA1A-down_3303 HMOX1-down_3162|HSPA1B-down_3304 HMOX1-down_3162|LDLR-down_3949 HMOX1-down_3162|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|LDLR-down_3949 IRS2-down_8660|LDLR-down_3949 THBS1-down_7057|LDLR-down_3949 TNC-up_3371|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa04144	hsa05219	Endocytosis - Homo sapiens (human)	ADRB1,ARRB1,CAV2,CXCR2,FLT1,HSPA1A,HSPA1B,LDLR,PDGFRA,DNM1,FOLR2,PSD3,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.013	ARRB1-down CCND1-up|CAV2-down CCND1-up|CAV2-down MMP2-up|CXCR2-down CCND1-up|FLT1-down CCND1-up|HSPA1A-down CCND1-up|LDLR-down CCND1-up|PDGFRA-down CCND1-up|TGFB3-up CCND1-up|CXCR2-down MMP1-up|CXCR2-down MMP2-up|CXCR2-down THBS1-down|FLT1-down HBEGF-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down THBS1-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|LDLR-down MMP1-up|LDLR-down MMP2-up|LDLR-down THBS1-down|PDGFRA-down MMP1-up|TGFB3-up MMP1-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|PDGFRA-down THBS1-down|TGFB3-up THBS1-down	ARRB1-down_408 CCND1-up_595|CAV2-down_858 CCND1-up_595|CAV2-down_858 MMP2-up_4313|CXCR2-down_3579 CCND1-up_595|FLT1-down_2321 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|LDLR-down_3949 CCND1-up_595|PDGFRA-down_5156 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CXCR2-down_3579 MMP1-up_4312|CXCR2-down_3579 MMP2-up_4313|CXCR2-down_3579 THBS1-down_7057|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 THBS1-down_7057|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|LDLR-down_3949 MMP1-up_4312|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 THBS1-down_7057|PDGFRA-down_5156 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057
hsa04151	hsa04310	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0	CCND1-up CSF3R-down|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up MCL1-down|CCND1-up PDGFRA-down|CCND1-up THBS1-down|CCND2-up FLT1-down|CCND2-up JAK1-down|CCND2-up MCL1-down|CCND2-up PDGFRA-down|CCND2-up THBS1-down|COL1A1-up JUN-down|COL1A1-up MMP7-up|COL1A1-up SERPINF1-up|COL1A1-up SFRP2-up|COL1A1-up SFRP4-up|COL1A1-up TCF7L2-up|COL1A2-up JUN-down|COL1A2-up MMP7-up|COL1A2-up SERPINF1-up|COL1A2-up SFRP2-up|COL1A2-up SFRP4-up|COL6A1-up JUN-down|COL6A1-up MMP7-up|COL6A1-up SERPINF1-up|COL6A3-up JUN-down|COL6A3-up MMP7-up|COL6A3-up SERPINF1-up|COMP-up JUN-down|COMP-up MMP7-up|CSF3R-down JUN-down|FGF14-up FZD5-down|FGF14-up SFRP4-up|FGF14-up TCF7L2-up|FIGF-down JUN-down|FIGF-down MMP7-up|FIGF-down SERPINF1-up|FLT1-down FZD5-down|FLT1-down JUN-down|FLT1-down MMP7-up|FLT1-down SERPINF1-up|FLT1-down SFRP2-up|ITGB8-up FZD5-down|PDGFRA-down FZD5-down|IGF1-up JUN-down|IGF1-up MMP7-up|IGF1-up SERPINF1-up|IGF1-up SFRP2-up|IGF1-up SFRP4-up|IGF1-up TCF7L2-up|ITGB4-up JUN-down|JAK1-down JUN-down|LAMA3-down JUN-down|MCL1-down JUN-down|MYB-up JUN-down|PDGFRA-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down MMP7-up|SPP1-up MMP7-up|THBS1-down MMP7-up|THBS2-up MMP7-up|TNC-up MMP7-up|MYB-up TCF7L2-up|PDGFRA-down SFRP2-up|PDGFRA-down SFRP4-up|PDGFRA-down TCF7L2-up|SPP1-up SERPINF1-up|THBS1-down SERPINF1-up|THBS2-up SERPINF1-up|TNC-up SERPINF1-up|SPP1-up SFRP2-up|THBS1-down SFRP2-up|TNC-up SFRP2-up|SPP1-up SFRP4-up|THBS1-down SFRP4-up|THBS2-up SFRP4-up	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 MCL1-down_4170|CCND1-up_595 PDGFRA-down_5156|CCND1-up_595 THBS1-down_7057|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JAK1-down_3716|CCND2-up_894 MCL1-down_4170|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 THBS1-down_7057|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP7-up_4316|COL1A1-up_1277 SERPINF1-up_5176|COL1A1-up_1277 SFRP2-up_6423|COL1A1-up_1277 SFRP4-up_6424|COL1A1-up_1277 TCF7L2-up_6934|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP7-up_4316|COL1A2-up_1278 SERPINF1-up_5176|COL1A2-up_1278 SFRP2-up_6423|COL1A2-up_1278 SFRP4-up_6424|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP7-up_4316|COL6A1-up_1291 SERPINF1-up_5176|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP7-up_4316|COL6A3-up_1293 SERPINF1-up_5176|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP7-up_4316|CSF3R-down_1441 JUN-down_3725|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 SFRP4-up_6424|FGF14-up_2259 TCF7L2-up_6934|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP7-up_4316|FIGF-down_2277 SERPINF1-up_5176|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP7-up_4316|FLT1-down_2321 SERPINF1-up_5176|FLT1-down_2321 SFRP2-up_6423|ITGB8-up_3696 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP7-up_4316|IGF1-up_3479 SERPINF1-up_5176|IGF1-up_3479 SFRP2-up_6423|IGF1-up_3479 SFRP4-up_6424|IGF1-up_3479 TCF7L2-up_6934|ITGB4-up_3691 JUN-down_3725|JAK1-down_3716 JUN-down_3725|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 MMP7-up_4316|SPP1-up_6696 MMP7-up_4316|THBS1-down_7057 MMP7-up_4316|THBS2-up_7058 MMP7-up_4316|TNC-up_3371 MMP7-up_4316|MYB-up_4602 TCF7L2-up_6934|PDGFRA-down_5156 SFRP2-up_6423|PDGFRA-down_5156 SFRP4-up_6424|PDGFRA-down_5156 TCF7L2-up_6934|SPP1-up_6696 SERPINF1-up_5176|THBS1-down_7057 SERPINF1-up_5176|THBS2-up_7058 SERPINF1-up_5176|TNC-up_3371 SERPINF1-up_5176|SPP1-up_6696 SFRP2-up_6423|THBS1-down_7057 SFRP2-up_6423|TNC-up_3371 SFRP2-up_6423|SPP1-up_6696 SFRP4-up_6424|THBS1-down_7057 SFRP4-up_6424|THBS2-up_7058 SFRP4-up_6424
hsa04151	hsa04350	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0	CCND1-up ID1-down|CCND1-up SMAD6-down|CCND1-up TGFB3-up|CCND2-up SMAD6-down|CCND2-up TGFB3-up|COL1A1-up LTBP1-up|COL1A1-up SMAD6-down|COL1A1-up TGFB3-up|COL1A2-up LTBP1-up|COL1A2-up SMAD6-down|COL1A2-up TGFB3-up|COL6A1-up LTBP1-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|FGF14-up TGFB3-up|FIGF-down TGFB3-up|FIGF-down THBS1-down|FLT1-down ID1-down|FLT1-down SMAD6-down|FLT1-down TGFB3-up|FLT1-down THBS1-down|IGF1-up ID1-down|MYB-up ID1-down|PDGFRA-down ID1-down|SPP1-up ID1-down|THBS2-up ID1-down|IGF1-up SMAD6-down|IGF1-up TGFB3-up|ITGB8-up TGFB3-up|JAK1-down SMAD6-down|LAMA3-down LTBP1-up|LAMA3-down THBS1-down|PDGFRA-down LTBP1-up|THBS2-up LTBP1-up|MCL1-down THBS1-down|PDGFRA-down TGFB3-up|PDGFRA-down THBS1-down|SPP1-up SMAD6-down|TNC-up SMAD6-down|SPP1-up TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CCND1-up_595 ID1-down_3397|CCND1-up_595 SMAD6-down_4091|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 SMAD6-down_4091|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 LTBP1-up_4052|COL1A1-up_1277 SMAD6-down_4091|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 LTBP1-up_4052|COL1A2-up_1278 SMAD6-down_4091|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 LTBP1-up_4052|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SMAD6-down_4091|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 ID1-down_3397|MYB-up_4602 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|SPP1-up_6696 ID1-down_3397|THBS2-up_7058 ID1-down_3397|IGF1-up_3479 SMAD6-down_4091|IGF1-up_3479 TGFB3-up_7043|ITGB8-up_3696 TGFB3-up_7043|JAK1-down_3716 SMAD6-down_4091|LAMA3-down_3909 LTBP1-up_4052|LAMA3-down_3909 THBS1-down_7057|PDGFRA-down_5156 LTBP1-up_4052|THBS2-up_7058 LTBP1-up_4052|MCL1-down_4170 THBS1-down_7057|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 THBS1-down_7057|SPP1-up_6696 SMAD6-down_4091|TNC-up_3371 SMAD6-down_4091|SPP1-up_6696 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04151	hsa04360	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0.002	FLT1-down BOC-up|MCL1-down BOC-up|CCND1-up CXCL12-up|CCND1-up EPHA3-up|CCND2-up CXCL12-up|COL1A1-up CXCL12-up|COL1A1-up EPHA3-up|COL1A2-up CXCL12-up|COL1A2-up EPHA3-up|COMP-up CXCL12-up|CSF3R-down CXCL12-up|FIGF-down CXCL12-up|FLT1-down CXCL12-up|IGF1-up CXCL12-up|JAK1-down CXCL12-up|MCL1-down CXCL12-up|MYB-up CXCL12-up|PDGFRA-down CXCL12-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|IGF1-up EPHA3-up|JAK1-down EPHA3-up|PDGFRA-down EPHA3-up|FLT1-down NTN1-up|FLT1-down RND1-down|FLT1-down ROBO2-up|FLT1-down SEMA3E-down|IGF1-up NTN1-up|JAK1-down RND1-down|PDGFRA-down NTN1-up|THBS1-down NTN1-up|THBS2-up NTN1-up|TNC-up NTN1-up|PDGFRA-down RND1-down|PDGFRA-down ROBO2-up|THBS1-down SEMA3E-down	FLT1-down_2321 BOC-up_91653|MCL1-down_4170 BOC-up_91653|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 EPHA3-up_2042|CCND2-up_894 CXCL12-up_6387|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 EPHA3-up_2042|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 EPHA3-up_2042|COMP-up_1311 CXCL12-up_6387|CSF3R-down_1441 CXCL12-up_6387|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|JAK1-down_3716 CXCL12-up_6387|MCL1-down_4170 CXCL12-up_6387|MYB-up_4602 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|IGF1-up_3479 EPHA3-up_2042|JAK1-down_3716 EPHA3-up_2042|PDGFRA-down_5156 EPHA3-up_2042|FLT1-down_2321 NTN1-up_9423|FLT1-down_2321 RND1-down_27289|FLT1-down_2321 ROBO2-up_6092|FLT1-down_2321 SEMA3E-down_9723|IGF1-up_3479 NTN1-up_9423|JAK1-down_3716 RND1-down_27289|PDGFRA-down_5156 NTN1-up_9423|THBS1-down_7057 NTN1-up_9423|THBS2-up_7058 NTN1-up_9423|TNC-up_3371 NTN1-up_9423|PDGFRA-down_5156 RND1-down_27289|PDGFRA-down_5156 ROBO2-up_6092|THBS1-down_7057 SEMA3E-down_9723
hsa04151	hsa04380	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0	CCND1-up CTSK-up|CCND1-up FHL2-up|CCND1-up FOSL2-down|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up FOSL2-down|CCND2-up JUN-down|CCND2-up SOCS3-down|COL1A1-up CTSK-up|COL1A1-up FOSL2-down|COL1A1-up JUN-down|COL1A1-up SOCS3-down|COL1A2-up CTSK-up|COL1A2-up FOSL2-down|COL1A2-up JUN-down|COL6A1-up CTSK-up|COL6A1-up JUN-down|COL6A3-up CTSK-up|COL6A3-up JUN-down|COMP-up CTSK-up|COMP-up FHL2-up|COMP-up JUN-down|CSF3R-down JAK1-down|CSF3R-down JUN-down|CSF3R-down SOCS3-down|IGF1-up CTSK-up|MCL1-down CTSK-up|SPP1-up CTSK-up|THBS1-down CTSK-up|THBS2-up CTSK-up|TNC-up CTSK-up|IGF1-up FHL2-up|TNC-up FHL2-up|FIGF-down JUN-down|FLT1-down FOSL2-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up FOSL2-down|LAMA3-down FOSL2-down|MCL1-down FOSL2-down|MYB-up FOSL2-down|IGF1-up JUN-down|IGF1-up SOCS3-down|ITGB4-up JUN-down|LAMA3-down JUN-down|MCL1-down JUN-down|MYB-up JUN-down|PDGFRA-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|MCL1-down SOCS3-down|MYB-up SOCS3-down|PDGFRA-down SOCS3-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	CCND1-up_595 CTSK-up_1513|CCND1-up_595 FHL2-up_2274|CCND1-up_595 FOSL2-down_2355|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 FOSL2-down_2355|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|COL1A1-up_1277 CTSK-up_1513|COL1A1-up_1277 FOSL2-down_2355|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 CTSK-up_1513|COL1A2-up_1278 FOSL2-down_2355|COL1A2-up_1278 JUN-down_3725|COL6A1-up_1291 CTSK-up_1513|COL6A1-up_1291 JUN-down_3725|COL6A3-up_1293 CTSK-up_1513|COL6A3-up_1293 JUN-down_3725|COMP-up_1311 CTSK-up_1513|COMP-up_1311 FHL2-up_2274|COMP-up_1311 JUN-down_3725|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 JUN-down_3725|CSF3R-down_1441 SOCS3-down_9021|IGF1-up_3479 CTSK-up_1513|MCL1-down_4170 CTSK-up_1513|SPP1-up_6696 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|THBS2-up_7058 CTSK-up_1513|TNC-up_3371 CTSK-up_1513|IGF1-up_3479 FHL2-up_2274|TNC-up_3371 FHL2-up_2274|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 FOSL2-down_2355|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 FOSL2-down_2355|LAMA3-down_3909 FOSL2-down_2355|MCL1-down_4170 FOSL2-down_2355|MYB-up_4602 FOSL2-down_2355|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|ITGB4-up_3691 JUN-down_3725|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|MCL1-down_4170 SOCS3-down_9021|MYB-up_4602 SOCS3-down_9021|PDGFRA-down_5156 SOCS3-down_9021|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04151	hsa04390	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0	CCND1-up CSF3R-down|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up MCL1-down|CCND1-up PDGFRA-down|CCND1-up THBS1-down|CCND2-up FLT1-down|CCND2-up JAK1-down|CCND2-up MCL1-down|CCND2-up PDGFRA-down|CCND2-up THBS1-down|COL1A1-up SERPINE1-down|COL1A1-up SOX2-up|COL1A1-up TCF7L2-up|COL1A1-up TGFB3-up|COL1A2-up SERPINE1-down|COL1A2-up SOX2-up|COL1A2-up TGFB3-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up SERPINE1-down|COMP-up TGFB3-up|FGF14-up FZD5-down|FGF14-up TCF7L2-up|FGF14-up TGFB3-up|FIGF-down SERPINE1-down|FIGF-down TGFB3-up|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down SERPINE1-down|FLT1-down SOX2-up|FLT1-down TGFB3-up|ITGB8-up FZD5-down|PDGFRA-down FZD5-down|IGF1-up ID1-down|MYB-up ID1-down|PDGFRA-down ID1-down|SPP1-up ID1-down|THBS1-down ID1-down|THBS2-up ID1-down|IGF1-up SERPINE1-down|IGF1-up SOX2-up|IGF1-up TCF7L2-up|IGF1-up TGFB3-up|ITGB8-up TGFB3-up|JAK1-down SERPINE1-down|LAMA3-down SERPINE1-down|MCL1-down SERPINE1-down|MCL1-down SOX2-up|MYB-up SERPINE1-down|MYB-up SOX2-up|MYB-up TCF7L2-up|PDGFRA-down SOX2-up|PDGFRA-down TCF7L2-up|PDGFRA-down TGFB3-up|SPP1-up SERPINE1-down|THBS1-down SERPINE1-down|THBS2-up SERPINE1-down|TNC-up SERPINE1-down|SPP1-up SOX2-up|THBS1-down SOX2-up|TNC-up SOX2-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 MCL1-down_4170|CCND1-up_595 PDGFRA-down_5156|CCND1-up_595 THBS1-down_7057|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JAK1-down_3716|CCND2-up_894 MCL1-down_4170|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 THBS1-down_7057|COL1A1-up_1277 SERPINE1-down_5054|COL1A1-up_1277 SOX2-up_6657|COL1A1-up_1277 TCF7L2-up_6934|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 SERPINE1-down_5054|COL1A2-up_1278 SOX2-up_6657|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 SERPINE1-down_5054|COMP-up_1311 TGFB3-up_7043|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TCF7L2-up_6934|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 SERPINE1-down_5054|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 SOX2-up_6657|FLT1-down_2321 TGFB3-up_7043|ITGB8-up_3696 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|IGF1-up_3479 ID1-down_3397|MYB-up_4602 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|SPP1-up_6696 ID1-down_3397|THBS1-down_7057 ID1-down_3397|THBS2-up_7058 ID1-down_3397|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 SOX2-up_6657|IGF1-up_3479 TCF7L2-up_6934|IGF1-up_3479 TGFB3-up_7043|ITGB8-up_3696 TGFB3-up_7043|JAK1-down_3716 SERPINE1-down_5054|LAMA3-down_3909 SERPINE1-down_5054|MCL1-down_4170 SERPINE1-down_5054|MCL1-down_4170 SOX2-up_6657|MYB-up_4602 SERPINE1-down_5054|MYB-up_4602 SOX2-up_6657|MYB-up_4602 TCF7L2-up_6934|PDGFRA-down_5156 SOX2-up_6657|PDGFRA-down_5156 TCF7L2-up_6934|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS2-up_7058 SERPINE1-down_5054|TNC-up_3371 SERPINE1-down_5054|SPP1-up_6696 SOX2-up_6657|THBS1-down_7057 SOX2-up_6657|TNC-up_3371 SOX2-up_6657|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04151	hsa04514	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CCND1-up CD274-down|CCND1-up CDH2-up|CCND1-up CDH3-up|CCND1-up NCAM1-up|CCND1-up VCAM1-up|CCND2-up CDH2-up|CCND2-up NCAM1-up|IGF1-up CD274-down|PDGFRA-down CD274-down|COL1A1-up CDH2-up|COL1A2-up CDH2-up|COMP-up CDH2-up|FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|ITGB4-up CDH2-up|JAK1-down CDH2-up|MCL1-down CDH2-up|MYB-up CDH2-up|PDGFRA-down CDH2-up|SPP1-up CDH2-up|THBS1-down CDH2-up|THBS2-up CDH2-up|TNC-up CDH2-up|LAMA3-down CDH3-up|TNC-up CDH3-up|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|MYB-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|MYB-up CLDN5-down|THBS1-down CLDN5-down|COL1A1-up ITGB8-up|COL1A1-up VCAM1-up|COL1A2-up ITGB8-up|COL1A2-up NCAM1-up|COL6A1-up ITGB8-up|COL6A3-up ITGB8-up|COMP-up ITGB8-up|CSF3R-down NCAM1-up|FGF14-up NFASC-up|FIGF-down VCAM1-up|FLT1-down NCAM1-up|FLT1-down SELL-down|FLT1-down VCAM1-up|IGF1-up NCAM1-up|IGF1-up SELL-down|IGF1-up VCAM1-up|ITGA10-down ITGB8-up|ITGB4-up ITGB8-up|ITGB4-up NCAM1-up|ITGB4-up VCAM1-up|ITGB8-up LAMA3-down|ITGB8-up MCL1-down|ITGB8-up THBS1-down|JAK1-down NCAM1-up|JAK1-down SELL-down|JAK1-down VCAM1-up|LAMA3-down VCAM1-up|MCL1-down NCAM1-up|MCL1-down SELL-down|MCL1-down VCAM1-up|MYB-up NCAM1-up|MYB-up VCAM1-up|PDGFRA-down NCAM1-up|SPP1-up NCAM1-up|THBS1-down NCAM1-up|TNC-up NCAM1-up|TNC-up NFASC-up|PDGFRA-down VCAM1-up|SPP1-up VCAM1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CCND1-up_595 CD274-down_29126|CCND1-up_595 CDH2-up_1000|CCND1-up_595 CDH3-up_1001|CCND1-up_595 NCAM1-up_4684|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CDH2-up_1000|CCND2-up_894 NCAM1-up_4684|IGF1-up_3479 CD274-down_29126|PDGFRA-down_5156 CD274-down_29126|COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COMP-up_1311 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|ITGB4-up_3691 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|MCL1-down_4170 CDH2-up_1000|MYB-up_4602 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|SPP1-up_6696 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS2-up_7058 CDH2-up_1000|TNC-up_3371 CDH2-up_1000|LAMA3-down_3909 CDH3-up_1001|TNC-up_3371 CDH3-up_1001|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|MYB-up_4602 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|MYB-up_4602 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 NCAM1-up_4684|COL6A1-up_1291 ITGB8-up_3696|COL6A3-up_1293 ITGB8-up_3696|COMP-up_1311 ITGB8-up_3696|CSF3R-down_1441 NCAM1-up_4684|FGF14-up_2259 NFASC-up_23114|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 NCAM1-up_4684|FLT1-down_2321 SELL-down_6402|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 NCAM1-up_4684|IGF1-up_3479 SELL-down_6402|IGF1-up_3479 VCAM1-up_7412|ITGA10-down_8515 ITGB8-up_3696|ITGB4-up_3691 ITGB8-up_3696|ITGB4-up_3691 NCAM1-up_4684|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 MCL1-down_4170|ITGB8-up_3696 THBS1-down_7057|JAK1-down_3716 NCAM1-up_4684|JAK1-down_3716 SELL-down_6402|JAK1-down_3716 VCAM1-up_7412|LAMA3-down_3909 VCAM1-up_7412|MCL1-down_4170 NCAM1-up_4684|MCL1-down_4170 SELL-down_6402|MCL1-down_4170 VCAM1-up_7412|MYB-up_4602 NCAM1-up_4684|MYB-up_4602 VCAM1-up_7412|PDGFRA-down_5156 NCAM1-up_4684|SPP1-up_6696 NCAM1-up_4684|THBS1-down_7057 NCAM1-up_4684|TNC-up_3371 NCAM1-up_4684|TNC-up_3371 NFASC-up_23114|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04151	hsa04550	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.003	CCND1-up FZD5-down|CCND1-up ID1-down|CCND1-up IGF1-up|CCND1-up LIFR-down|CCND1-up SOX2-up|CCND2-up FZD5-down|CCND2-up IGF1-up|CCND2-up SOX2-up|COL1A1-up IGF1-up|COL1A1-up SOX2-up|COL1A2-up IGF1-up|COL1A2-up SOX2-up|COMP-up IGF1-up|CSF3R-down JAK1-down|CSF3R-down LIFR-down|FGF14-up FZD5-down|FIGF-down IGF1-up|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down IGF1-up|FLT1-down JAK1-down|FLT1-down SOX2-up|ITGB8-up FZD5-down|PDGFRA-down FZD5-down|MYB-up ID1-down|PDGFRA-down ID1-down|SPP1-up ID1-down|THBS1-down ID1-down|THBS2-up ID1-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|SPP1-up LIFR-down|MCL1-down SOX2-up|MYB-up SOX2-up|PDGFRA-down SOX2-up|SPP1-up SOX2-up|THBS1-down SOX2-up|TNC-up SOX2-up	CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND1-up_595 IGF1-up_3479|CCND1-up_595 LIFR-down_3977|CCND1-up_595 SOX2-up_6657|CCND2-up_894 FZD5-down_7855|CCND2-up_894 IGF1-up_3479|CCND2-up_894 SOX2-up_6657|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 SOX2-up_6657|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 SOX2-up_6657|COMP-up_1311 IGF1-up_3479|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 LIFR-down_3977|FGF14-up_2259 FZD5-down_7855|FIGF-down_2277 IGF1-up_3479|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 SOX2-up_6657|ITGB8-up_3696 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|MYB-up_4602 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|SPP1-up_6696 ID1-down_3397|THBS1-down_7057 ID1-down_3397|THBS2-up_7058 ID1-down_3397|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|SPP1-up_6696 LIFR-down_3977|MCL1-down_4170 SOX2-up_6657|MYB-up_4602 SOX2-up_6657|PDGFRA-down_5156 SOX2-up_6657|SPP1-up_6696 SOX2-up_6657|THBS1-down_7057 SOX2-up_6657|TNC-up_3371 SOX2-up_6657
hsa04151	hsa04610	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0	CCND1-up CFH-up|CCND1-up PLAU-up|CCND1-up SERPINE1-down|CCND2-up PLAU-up|CCND2-up SERPINE1-down|FLT1-down CFH-up|IGF1-up CFH-up|PDGFRA-down CFH-up|SPP1-up CFH-up|THBS1-down CFH-up|COL1A1-up PLAU-up|COL1A1-up SERPINE1-down|COL1A2-up PLAU-up|COL1A2-up SERPINE1-down|COL6A3-up PLAU-up|COMP-up SERPINE1-down|FLT1-down F3-down|IGF1-up F3-down|PDGFRA-down F3-down|THBS1-down F3-down|THBS2-up F3-down|TNC-up F3-down|FIGF-down PLAU-up|FIGF-down SERPINE1-down|FLT1-down PLAU-up|FLT1-down SERPINE1-down|FLT1-down TFPI-down|IGF1-up SERPINE1-down|ITGB4-up PLAU-up|JAK1-down PLAU-up|JAK1-down SERPINE1-down|LAMA3-down PLAU-up|LAMA3-down SERPINE1-down|MCL1-down SERPINE1-down|MCL1-down TFPI-down|MYB-up SERPINE1-down|PDGFRA-down PLAU-up|SPP1-up PLAU-up|THBS1-down PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up|SPP1-up SERPINE1-down|THBS1-down SERPINE1-down|THBS2-up SERPINE1-down|TNC-up SERPINE1-down|SPP1-up TFPI-down|THBS1-down TFPI-down|THBS2-up TFPI-down|TNC-up TFPI-down	CCND1-up_595 CFH-up_3075|CCND1-up_595 PLAU-up_5328|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 PLAU-up_5328|CCND2-up_894 SERPINE1-down_5054|FLT1-down_2321 CFH-up_3075|IGF1-up_3479 CFH-up_3075|PDGFRA-down_5156 CFH-up_3075|SPP1-up_6696 CFH-up_3075|THBS1-down_7057 CFH-up_3075|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SERPINE1-down_5054|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 SERPINE1-down_5054|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 SERPINE1-down_5054|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|PDGFRA-down_5156 F3-down_2152|THBS1-down_7057 F3-down_2152|THBS2-up_7058 F3-down_2152|TNC-up_3371 F3-down_2152|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 SERPINE1-down_5054|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TFPI-down_7035|IGF1-up_3479 SERPINE1-down_5054|ITGB4-up_3691 PLAU-up_5328|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 SERPINE1-down_5054|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 SERPINE1-down_5054|MCL1-down_4170 SERPINE1-down_5054|MCL1-down_4170 TFPI-down_7035|MYB-up_4602 SERPINE1-down_5054|PDGFRA-down_5156 PLAU-up_5328|SPP1-up_6696 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328|SPP1-up_6696 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS2-up_7058 SERPINE1-down_5054|TNC-up_3371 SERPINE1-down_5054|SPP1-up_6696 TFPI-down_7035|THBS1-down_7057 TFPI-down_7035|THBS2-up_7058 TFPI-down_7035|TNC-up_3371 TFPI-down_7035
hsa04151	hsa04668	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	CCND1-up JUN-down|CCND1-up MAP3K8-down|CCND1-up SOCS3-down|CCND1-up VCAM1-up|CCND2-up CXCL2-down|CCND2-up JUN-down|CCND2-up MAP3K8-down|CCND2-up SOCS3-down|COL1A1-up CXCL2-down|COL1A1-up JUN-down|COL1A1-up SOCS3-down|COL1A1-up VCAM1-up|COL1A2-up JUN-down|COL6A1-up JUN-down|COL6A3-up JUN-down|COMP-up JUN-down|CSF3R-down JUN-down|CSF3R-down SOCS3-down|IGF1-up CXCL2-down|MYB-up CXCL2-down|SPP1-up CXCL2-down|FIGF-down JUN-down|FIGF-down VCAM1-up|FLT1-down JUN-down|FLT1-down SOCS3-down|FLT1-down VCAM1-up|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|ITGB4-up JUN-down|ITGB4-up VCAM1-up|JAK1-down JUN-down|JAK1-down SOCS3-down|JAK1-down VCAM1-up|LAMA3-down JUN-down|MCL1-down JUN-down|MYB-up JUN-down|PDGFRA-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down VCAM1-up|MCL1-down MAP3K8-down|MYB-up MAP3K8-down|PDGFRA-down MAP3K8-down|PRKAA2-up MAP3K8-down|MCL1-down SOCS3-down|MCL1-down VCAM1-up|MYB-up SOCS3-down|MYB-up VCAM1-up|PDGFRA-down SOCS3-down|PDGFRA-down VCAM1-up|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down|SPP1-up VCAM1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CCND1-up_595 JUN-down_3725|CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 SOCS3-down_9021|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL2-down_2920|CCND2-up_894 JUN-down_3725|CCND2-up_894 MAP3K8-down_1326|CCND2-up_894 SOCS3-down_9021|COL1A1-up_1277 CXCL2-down_2920|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SOCS3-down_9021|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JUN-down_3725|COL6A1-up_1291 JUN-down_3725|COL6A3-up_1293 JUN-down_3725|COMP-up_1311 JUN-down_3725|CSF3R-down_1441 JUN-down_3725|CSF3R-down_1441 SOCS3-down_9021|IGF1-up_3479 CXCL2-down_2920|MYB-up_4602 CXCL2-down_2920|SPP1-up_6696 CXCL2-down_2920|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 VCAM1-up_7412|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 SOCS3-down_9021|JAK1-down_3716 VCAM1-up_7412|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 VCAM1-up_7412|MCL1-down_4170 MAP3K8-down_1326|MYB-up_4602 MAP3K8-down_1326|PDGFRA-down_5156 MAP3K8-down_1326|PRKAA2-up_5563 MAP3K8-down_1326|MCL1-down_4170 SOCS3-down_9021|MCL1-down_4170 VCAM1-up_7412|MYB-up_4602 SOCS3-down_9021|MYB-up_4602 VCAM1-up_7412|PDGFRA-down_5156 SOCS3-down_9021|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04151	hsa04670	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|CCND2-up CXCL12-up|CCND2-up MMP2-up|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|MYB-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|MYB-up CLDN5-down|THBS1-down CLDN5-down|COL1A1-up CXCL12-up|COL1A1-up MMP2-up|COL1A1-up THY1-up|COL1A1-up VCAM1-up|COL1A2-up CXCL12-up|COL1A2-up MMP2-up|COL6A1-up MMP2-up|COL6A3-up MMP2-up|COMP-up CXCL12-up|COMP-up MMP2-up|CSF3R-down CXCL12-up|FIGF-down CXCL12-up|FLT1-down CXCL12-up|IGF1-up CXCL12-up|JAK1-down CXCL12-up|MCL1-down CXCL12-up|MYB-up CXCL12-up|PDGFRA-down CXCL12-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|FIGF-down MMP2-up|FIGF-down VCAM1-up|FLT1-down MMP2-up|FLT1-down VCAM1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up|ITGB4-up MMP2-up|ITGB4-up THY1-up|ITGB4-up VCAM1-up|JAK1-down MMP2-up|JAK1-down VCAM1-up|LAMA3-down MMP2-up|LAMA3-down VCAM1-up|MCL1-down MMP2-up|MCL1-down VCAM1-up|MYB-up MMP2-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|MYB-up THY1-up|MYB-up VCAM1-up|PDGFRA-down VCAM1-up|SPP1-up THY1-up|SPP1-up VCAM1-up|THBS1-down THY1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP2-up_4313|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|MYB-up_4602 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|MYB-up_4602 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 THY1-up_7070|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 MMP2-up_4313|CSF3R-down_1441 CXCL12-up_6387|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|JAK1-down_3716 CXCL12-up_6387|MCL1-down_4170 CXCL12-up_6387|MYB-up_4602 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 THY1-up_7070|ITGB4-up_3691 VCAM1-up_7412|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 VCAM1-up_7412|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 VCAM1-up_7412|MCL1-down_4170 MMP2-up_4313|MCL1-down_4170 VCAM1-up_7412|MYB-up_4602 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|MYB-up_4602 THY1-up_7070|MYB-up_4602 VCAM1-up_7412|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 THY1-up_7070|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 THY1-up_7070|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04151	hsa04915	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	CCND1-up HBEGF-down|CCND1-up HSPA1A-down|CCND1-up JUN-down|CCND1-up MMP2-up|CCND2-up HBEGF-down|CCND2-up JUN-down|CCND2-up MMP2-up|COL1A1-up HSPA1A-down|COL1A1-up JUN-down|COL1A1-up MMP2-up|COL1A2-up JUN-down|COL1A2-up MMP2-up|COL6A1-up JUN-down|COL6A1-up MMP2-up|COL6A3-up JUN-down|COL6A3-up MMP2-up|COMP-up JUN-down|COMP-up MMP2-up|CSF3R-down JUN-down|FIGF-down HBEGF-down|FIGF-down JUN-down|FIGF-down MMP2-up|FLT1-down HBEGF-down|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JUN-down|FLT1-down MMP2-up|SPP1-up GABBR1-up|JAK1-down GABBR2-up|SPP1-up GABBR2-up|IGF1-up HBEGF-down|LAMA3-down HBEGF-down|MCL1-down HBEGF-down|PDGFRA-down HBEGF-down|SPP1-up HBEGF-down|THBS1-down HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|IGF1-up HSPA1A-down|JAK1-down HSPA1A-down|PDGFRA-down HSPA1A-down|JAK1-down HSPA1B-down|PDGFRA-down HSPA1B-down|IGF1-up JUN-down|IGF1-up MMP2-up|ITGB4-up JUN-down|ITGB4-up MMP2-up|JAK1-down JUN-down|JAK1-down MMP2-up|LAMA3-down JUN-down|MCL1-down JUN-down|MYB-up JUN-down|PDGFRA-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down MMP2-up|MCL1-down MMP2-up|MYB-up MMP2-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up	CCND1-up_595 HBEGF-down_1839|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP2-up_4313|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|COL1A1-up_1277 HSPA1A-down_3303|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP2-up_4313|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP2-up_4313|CSF3R-down_1441 JUN-down_3725|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP2-up_4313|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|SPP1-up_6696 GABBR1-up_2550|JAK1-down_3716 GABBR2-up_9568|SPP1-up_6696 GABBR2-up_9568|IGF1-up_3479 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|MCL1-down_4170 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS1-down_7057 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|IGF1-up_3479 HSPA1A-down_3303|JAK1-down_3716 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|JAK1-down_3716 HSPA1B-down_3304|PDGFRA-down_5156 HSPA1B-down_3304|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP2-up_4313|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP2-up_4313|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 MMP2-up_4313|MCL1-down_4170 MMP2-up_4313|MYB-up_4602 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313
hsa04151	hsa04933	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CCND1-up CSF3R-down|CCND1-up FLT1-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up MCL1-down|CCND1-up PDGFRA-down|CCND1-up THBS1-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up JUN-down|CCND2-up MMP2-up|CCND2-up SERPINE1-down|CCND2-up TGFB3-up|COL1A1-up FLT1-down|COL1A1-up ITGA10-down|COL1A1-up LAMA3-down|COL1A1-up PDGFRA-down|COL1A1-up THBS1-down|COL1A2-up FLT1-down|COL1A2-up JAK1-down|COL1A2-up LAMA3-down|COL1A2-up PDGFRA-down|COL1A2-up THBS1-down|COL6A1-up COL3A1-up|COL6A3-up COL3A1-up|COMP-up COL3A1-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|LAMA3-down COL3A1-up|PDGFRA-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COL6A1-up JUN-down|COL6A1-up MMP2-up|COL6A1-up TGFB3-up|COL6A3-up JUN-down|COL6A3-up MMP2-up|COL6A3-up TGFB3-up|COMP-up JUN-down|COMP-up MMP2-up|COMP-up SERPINE1-down|COMP-up TGFB3-up|CSF3R-down JUN-down|FLT1-down F3-down|IGF1-up F3-down|PDGFRA-down F3-down|THBS1-down F3-down|THBS2-up F3-down|TNC-up F3-down|FGF14-up TGFB3-up|FLT1-down JUN-down|FLT1-down MMP2-up|FLT1-down SERPINE1-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|ITGB4-up JUN-down|ITGB4-up MMP2-up|ITGB4-up VCAM1-up|ITGB8-up TGFB3-up|JAK1-down JUN-down|JAK1-down MMP2-up|JAK1-down SERPINE1-down|JAK1-down VCAM1-up|LAMA3-down JUN-down|MCL1-down JUN-down|MYB-up JUN-down|PDGFRA-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down MMP2-up|LAMA3-down SERPINE1-down|LAMA3-down VCAM1-up|MCL1-down MMP2-up|MCL1-down SERPINE1-down|MCL1-down VCAM1-up|MYB-up MMP2-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|MYB-up SERPINE1-down|MYB-up VCAM1-up|PDGFRA-down TGFB3-up|PDGFRA-down VCAM1-up|SPP1-up SERPINE1-down|THBS1-down SERPINE1-down|THBS2-up SERPINE1-down|TNC-up SERPINE1-down|SPP1-up TGFB3-up|SPP1-up VCAM1-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 MCL1-down_4170|CCND1-up_595 PDGFRA-down_5156|CCND1-up_595 THBS1-down_7057|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|CCND2-up_894 SERPINE1-down_5054|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 THBS1-down_7057|COL6A1-up_1291 COL3A1-up_1281|COL6A3-up_1293 COL3A1-up_1281|COMP-up_1311 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|LAMA3-down_3909 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP2-up_4313|COMP-up_1311 SERPINE1-down_5054|COMP-up_1311 TGFB3-up_7043|CSF3R-down_1441 JUN-down_3725|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|PDGFRA-down_5156 F3-down_2152|THBS1-down_7057 F3-down_2152|THBS2-up_7058 F3-down_2152|TNC-up_3371 F3-down_2152|FGF14-up_2259 TGFB3-up_7043|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 TGFB3-up_7043|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 SERPINE1-down_5054|JAK1-down_3716 VCAM1-up_7412|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 SERPINE1-down_5054|LAMA3-down_3909 VCAM1-up_7412|MCL1-down_4170 MMP2-up_4313|MCL1-down_4170 SERPINE1-down_5054|MCL1-down_4170 VCAM1-up_7412|MYB-up_4602 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|MYB-up_4602 SERPINE1-down_5054|MYB-up_4602 VCAM1-up_7412|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS2-up_7058 SERPINE1-down_5054|TNC-up_3371 SERPINE1-down_5054|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04151	hsa04974	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CCND1-up COL18A1-up|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up MME-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up MME-down|COMP-up COL10A1-up|SPP1-up COL10A1-up|THBS1-down COL10A1-up|COMP-up COL14A1-up|FGF14-up COL14A1-up|ITGB8-up COL14A1-up|LAMA3-down COL14A1-up|THBS1-down COL14A1-up|THBS2-up COL14A1-up|COMP-up COL15A1-up|LAMA3-down COL15A1-up|THBS1-down COL15A1-up|THBS2-up COL15A1-up|TNC-up COL15A1-up|COMP-up COL17A1-up|ITGB4-up COL17A1-up|LAMA3-down COL17A1-up|THBS1-down COL17A1-up|THBS2-up COL17A1-up|COMP-up COL18A1-up|FIGF-down COL18A1-up|FLT1-down COL18A1-up|IGF1-up COL18A1-up|LAMA3-down COL18A1-up|MCL1-down COL18A1-up|MYB-up COL18A1-up|SPP1-up COL18A1-up|THBS1-down COL18A1-up|THBS2-up COL18A1-up|TNC-up COL18A1-up|COL1A1-up FIGF-down|COL1A1-up FLT1-down|COL1A1-up ITGA10-down|COL1A1-up LAMA3-down|COL1A1-up PDGFRA-down|COL1A1-up THBS1-down|COL1A2-up FIGF-down|COL1A2-up FLT1-down|COL1A2-up JAK1-down|COL1A2-up LAMA3-down|COL1A2-up PDGFRA-down|COL1A2-up THBS1-down|COMP-up COL3A1-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|LAMA3-down COL3A1-up|PDGFRA-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COMP-up COL5A1-up|FLT1-down COL5A1-up|IGF1-up COL5A1-up|ITGA10-down COL5A1-up|ITGB4-up COL5A1-up|ITGB8-up COL5A1-up|LAMA3-down COL5A1-up|PDGFRA-down COL5A1-up|SPP1-up COL5A1-up|THBS1-down COL5A1-up|THBS2-up COL5A1-up|TNC-up COL5A1-up|COMP-up COL5A2-up|ITGB4-up COL5A2-up|ITGB8-up COL5A2-up|LAMA3-down COL5A2-up|SPP1-up COL5A2-up|THBS1-down COL5A2-up|THBS2-up COL5A2-up|TNC-up COL5A2-up|COL6A1-up LAMA3-down|COL6A1-up PDGFRA-down|COL6A1-up THBS1-down|COL6A3-up LAMA3-down|COL6A3-up PDGFRA-down|COL6A3-up THBS1-down|COMP-up COL7A1-up|ITGB4-up COL7A1-up|LAMA3-down COL7A1-up|THBS1-down COL7A1-up|THBS2-up COL7A1-up|MCL1-down CPA3-up|FLT1-down MME-down|IGF1-up MME-down|IGF1-up PRSS1-up|IGF1-up SLC1A1-down|ITGB4-up MME-down|MCL1-down MME-down|MYB-up MME-down|PDGFRA-down MME-down|SPP1-up MME-down|THBS1-down MME-down	CCND1-up_595 COL18A1-up_80781|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 MME-down_4311|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 MME-down_4311|COMP-up_1311 COL10A1-up_1300|SPP1-up_6696 COL10A1-up_1300|THBS1-down_7057 COL10A1-up_1300|COMP-up_1311 COL14A1-up_7373|FGF14-up_2259 COL14A1-up_7373|ITGB8-up_3696 COL14A1-up_7373|LAMA3-down_3909 COL14A1-up_7373|THBS1-down_7057 COL14A1-up_7373|THBS2-up_7058 COL14A1-up_7373|COMP-up_1311 COL15A1-up_1306|LAMA3-down_3909 COL15A1-up_1306|THBS1-down_7057 COL15A1-up_1306|THBS2-up_7058 COL15A1-up_1306|TNC-up_3371 COL15A1-up_1306|COMP-up_1311 COL17A1-up_1308|ITGB4-up_3691 COL17A1-up_1308|LAMA3-down_3909 COL17A1-up_1308|THBS1-down_7057 COL17A1-up_1308|THBS2-up_7058 COL17A1-up_1308|COMP-up_1311 COL18A1-up_80781|FIGF-down_2277 COL18A1-up_80781|FLT1-down_2321 COL18A1-up_80781|IGF1-up_3479 COL18A1-up_80781|LAMA3-down_3909 COL18A1-up_80781|MCL1-down_4170 COL18A1-up_80781|MYB-up_4602 COL18A1-up_80781|SPP1-up_6696 COL18A1-up_80781|THBS1-down_7057 COL18A1-up_80781|THBS2-up_7058 COL18A1-up_80781|TNC-up_3371 COL18A1-up_80781|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 THBS1-down_7057|COMP-up_1311 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|LAMA3-down_3909 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COMP-up_1311 COL5A1-up_1289|FLT1-down_2321 COL5A1-up_1289|IGF1-up_3479 COL5A1-up_1289|ITGA10-down_8515 COL5A1-up_1289|ITGB4-up_3691 COL5A1-up_1289|ITGB8-up_3696 COL5A1-up_1289|LAMA3-down_3909 COL5A1-up_1289|PDGFRA-down_5156 COL5A1-up_1289|SPP1-up_6696 COL5A1-up_1289|THBS1-down_7057 COL5A1-up_1289|THBS2-up_7058 COL5A1-up_1289|TNC-up_3371 COL5A1-up_1289|COMP-up_1311 COL5A2-up_1290|ITGB4-up_3691 COL5A2-up_1290|ITGB8-up_3696 COL5A2-up_1290|LAMA3-down_3909 COL5A2-up_1290|SPP1-up_6696 COL5A2-up_1290|THBS1-down_7057 COL5A2-up_1290|THBS2-up_7058 COL5A2-up_1290|TNC-up_3371 COL5A2-up_1290|COL6A1-up_1291 LAMA3-down_3909|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 THBS1-down_7057|COL6A3-up_1293 LAMA3-down_3909|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 THBS1-down_7057|COMP-up_1311 COL7A1-up_1294|ITGB4-up_3691 COL7A1-up_1294|LAMA3-down_3909 COL7A1-up_1294|THBS1-down_7057 COL7A1-up_1294|THBS2-up_7058 COL7A1-up_1294|MCL1-down_4170 CPA3-up_1359|FLT1-down_2321 MME-down_4311|IGF1-up_3479 MME-down_4311|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SLC1A1-down_6505|ITGB4-up_3691 MME-down_4311|MCL1-down_4170 MME-down_4311|MYB-up_4602 MME-down_4311|PDGFRA-down_5156 MME-down_4311|SPP1-up_6696 MME-down_4311|THBS1-down_7057 MME-down_4311
hsa04151	hsa04978	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0	CCND1-up HMOX1-down|CCND1-up TF-up|CCND2-up HMOX1-down|CCND2-up TF-up|COL1A1-up HMOX1-down|COL1A1-up TF-up|COL1A2-up HMOX1-down|COL1A2-up TF-up|COL6A1-up HMOX1-down|FIGF-down HMOX1-down|FLT1-down HMOX1-down|FLT1-down TF-up|IGF1-up HMOX1-down|JAK1-down HMOX1-down|MCL1-down HMOX1-down|MYB-up HMOX1-down|PDGFRA-down HMOX1-down|SPP1-up HMOX1-down|THBS1-down HMOX1-down|TNC-up HMOX1-down|IGF1-up TF-up|ITGB4-up MT1X-down|JAK1-down TF-up|MCL1-down MT1E-down|MCL1-down TF-up|MYB-up TF-up|PDGFRA-down TF-up|SPP1-up TF-up|THBS1-down TF-up|TNC-up TF-up	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|CCND2-up_894 HMOX1-down_3162|CCND2-up_894 TF-up_7018|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 TF-up_7018|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 TF-up_7018|COL6A1-up_1291 HMOX1-down_3162|FIGF-down_2277 HMOX1-down_3162|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 TF-up_7018|IGF1-up_3479 HMOX1-down_3162|JAK1-down_3716 HMOX1-down_3162|MCL1-down_4170 HMOX1-down_3162|MYB-up_4602 HMOX1-down_3162|PDGFRA-down_5156 HMOX1-down_3162|SPP1-up_6696 HMOX1-down_3162|THBS1-down_7057 HMOX1-down_3162|TNC-up_3371 HMOX1-down_3162|IGF1-up_3479 TF-up_7018|ITGB4-up_3691 MT1X-down_4501|JAK1-down_3716 TF-up_7018|MCL1-down_4170 MT1E-down_4493|MCL1-down_4170 TF-up_7018|MYB-up_4602 TF-up_7018|PDGFRA-down_5156 TF-up_7018|SPP1-up_6696 TF-up_7018|THBS1-down_7057 TF-up_7018|TNC-up_3371 TF-up_7018
hsa04151	hsa05146	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up TGFB3-up|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up TGFB3-up|COL1A1-up FIGF-down|COL1A1-up FLT1-down|COL1A1-up ITGA10-down|COL1A1-up PDGFRA-down|COL1A1-up THBS1-down|COL1A2-up FIGF-down|COL1A2-up FLT1-down|COL1A2-up JAK1-down|COL1A2-up PDGFRA-down|COL1A2-up THBS1-down|COL6A1-up COL3A1-up|COL6A3-up COL3A1-up|COMP-up COL3A1-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|PDGFRA-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down TGFB3-up|IGF1-up TGFB3-up|SPP1-up IL1R2-down|ITGA10-down LAMA3-down|ITGB8-up TGFB3-up|MCL1-down SERPINB3-up|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 THBS1-down_7057|COL6A1-up_1291 COL3A1-up_1281|COL6A3-up_1293 COL3A1-up_1281|COMP-up_1311 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 TGFB3-up_7043|SPP1-up_6696 IL1R2-down_7850|ITGA10-down_8515 LAMA3-down_3909|ITGB8-up_3696 TGFB3-up_7043|MCL1-down_4170 SERPINB3-up_6317|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04151	hsa05152	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.009	CCND1-up CD74-up|CCND1-up TGFB3-up|CCND2-up TGFB3-up|COL1A1-up CD74-up|COL1A2-up CD74-up|FIGF-down CD74-up|IGF1-up CD74-up|THBS1-down CD74-up|COL1A1-up TGFB3-up|COL1A2-up TGFB3-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|CSF3R-down JAK1-down|FGF14-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down JAK1-down|FLT1-down TGFB3-up|IGF1-up TGFB3-up|ITGB8-up TGFB3-up|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CCND1-up_595 CD74-up_972|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|THBS1-down_7057 CD74-up_972|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|CSF3R-down_1441 JAK1-down_3716|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 TGFB3-up_7043|ITGB8-up_3696 TGFB3-up_7043|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04151	hsa05160	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0.006	CCND1-up LDLR-down|CCND1-up SOCS3-down|CCND2-up SOCS3-down|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|MYB-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|MYB-up CLDN5-down|THBS1-down CLDN5-down|COL1A1-up LDLR-down|COL1A1-up SOCS3-down|CSF3R-down JAK1-down|CSF3R-down SOCS3-down|FLT1-down JAK1-down|FLT1-down LDLR-down|FLT1-down SOCS3-down|IGF1-up LDLR-down|IGF1-up SOCS3-down|MYB-up LDLR-down|THBS1-down LDLR-down|TNC-up LDLR-down|MCL1-down SOCS3-down|MYB-up SOCS3-down|PDGFRA-down SOCS3-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	CCND1-up_595 LDLR-down_3949|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 SOCS3-down_9021|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|MYB-up_4602 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|MYB-up_4602 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 SOCS3-down_9021|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 SOCS3-down_9021|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 LDLR-down_3949|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 SOCS3-down_9021|MYB-up_4602 LDLR-down_3949|THBS1-down_7057 LDLR-down_3949|TNC-up_3371 LDLR-down_3949|MCL1-down_4170 SOCS3-down_9021|MYB-up_4602 SOCS3-down_9021|PDGFRA-down_5156 SOCS3-down_9021|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04151	hsa05166	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	CCND1-up CSF3R-down|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up LAMA3-down|CCND1-up MCL1-down|CCND1-up THBS1-down|CCND2-up FLT1-down|CCND2-up MCL1-down|CCND2-up THBS1-down|COL1A1-up JUN-down|COL1A1-up MYB-up|COL1A1-up TGFB3-up|COL1A1-up VCAM1-up|COL1A2-up JUN-down|COL1A2-up MYB-up|COL1A2-up TGFB3-up|COL6A1-up JUN-down|COL6A1-up MYB-up|COL6A1-up TGFB3-up|COL6A3-up JUN-down|COL6A3-up TGFB3-up|COMP-up JUN-down|COMP-up TGFB3-up|CSF3R-down JAK1-down|CSF3R-down JUN-down|FGF14-up FZD5-down|FGF14-up TGFB3-up|FIGF-down JUN-down|FIGF-down PDGFRA-down|FIGF-down TGFB3-up|FIGF-down VCAM1-up|FLT1-down FZD5-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MYB-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|ITGB8-up FZD5-down|IGF1-up JUN-down|IGF1-up MYB-up|IGF1-up TGFB3-up|IGF1-up VCAM1-up|SPP1-up IL1R2-down|ITGB4-up JUN-down|ITGB4-up MYB-up|ITGB4-up VCAM1-up|ITGB8-up TGFB3-up|LAMA3-down JUN-down|MCL1-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down VCAM1-up|MCL1-down MYB-up|MCL1-down PDGFRA-down|MCL1-down VCAM1-up|MYB-up THBS1-down|SPP1-up TGFB3-up|SPP1-up VCAM1-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 MCL1-down_4170|CCND1-up_595 THBS1-down_7057|CCND2-up_894 FLT1-down_2321|CCND2-up_894 MCL1-down_4170|CCND2-up_894 THBS1-down_7057|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MYB-up_4602|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MYB-up_4602|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MYB-up_4602|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 JUN-down_3725|COMP-up_1311 TGFB3-up_7043|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 JUN-down_3725|FGF14-up_2259 FZD5-down_7855|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 VCAM1-up_7412|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MYB-up_4602|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|ITGB8-up_3696 FZD5-down_7855|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MYB-up_4602|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|SPP1-up_6696 IL1R2-down_7850|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MYB-up_4602|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 TGFB3-up_7043|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 VCAM1-up_7412|MCL1-down_4170 MYB-up_4602|MCL1-down_4170 PDGFRA-down_5156|MCL1-down_4170 VCAM1-up_7412|MYB-up_4602 THBS1-down_7057|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04151	hsa05168	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.003	CCND1-up CD74-up|CCND1-up JUN-down|CCND1-up SOCS3-down|CCND2-up JUN-down|CCND2-up SOCS3-down|COL1A1-up CD74-up|COL1A2-up CD74-up|FIGF-down CD74-up|IGF1-up CD74-up|THBS1-down CD74-up|COL1A1-up JUN-down|COL1A1-up SOCS3-down|COL1A2-up JUN-down|COL6A1-up JUN-down|COL6A3-up JUN-down|COMP-up JUN-down|CSF3R-down JAK1-down|CSF3R-down JUN-down|CSF3R-down SOCS3-down|FIGF-down JUN-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up JUN-down|IGF1-up SOCS3-down|ITGB4-up JUN-down|LAMA3-down JUN-down|MCL1-down JUN-down|MYB-up JUN-down|PDGFRA-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|MCL1-down SOCS3-down|MYB-up SOCS3-down|PDGFRA-down SOCS3-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	CCND1-up_595 CD74-up_972|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JUN-down_3725|CCND2-up_894 SOCS3-down_9021|COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|THBS1-down_7057 CD74-up_972|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JUN-down_3725|COL6A1-up_1291 JUN-down_3725|COL6A3-up_1293 JUN-down_3725|COMP-up_1311 JUN-down_3725|CSF3R-down_1441 JAK1-down_3716|CSF3R-down_1441 JUN-down_3725|CSF3R-down_1441 SOCS3-down_9021|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|ITGB4-up_3691 JUN-down_3725|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|MCL1-down_4170 SOCS3-down_9021|MYB-up_4602 SOCS3-down_9021|PDGFRA-down_5156 SOCS3-down_9021|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04151	hsa05200	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	CCND1-up FLT1-down|CCND1-up MCL1-down|CCND1-up THBS1-down|CCND2-up CXCL12-up|CCND2-up FZD5-down|CCND2-up HHIP-down|CCND2-up IGF1-up|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up TCF7L2-up|CCND2-up TGFB3-up|CCND2-up ZBTB16-down|COL1A1-up CXCL12-up|COL1A1-up IGF1-up|COL1A1-up JUN-down|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up TCF7L2-up|COL1A1-up TGFB3-up|COL1A1-up ZBTB16-down|COL1A2-up CXCL12-up|COL1A2-up EDNRB-down|COL1A2-up IGF1-up|COL1A2-up JUN-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up TGFB3-up|COL6A1-up JUN-down|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A1-up TGFB3-up|COL6A1-up ZBTB16-down|COL6A3-up JUN-down|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COL6A3-up TGFB3-up|COMP-up CXCL12-up|COMP-up IGF1-up|COMP-up JUN-down|COMP-up MMP1-up|COMP-up MMP2-up|COMP-up TGFB3-up|FLT1-down CXCL12-up|MCL1-down CXCL12-up|MYB-up CXCL12-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|PRKAA2-up DAPK2-down|FLT1-down EDNRB-down|MCL1-down EDNRB-down|SPP1-up EDNRB-down|THBS1-down EDNRB-down|TNC-up EDNRB-down|FGF14-up FLT1-down|FLT1-down FZD5-down|FLT1-down IGF1-up|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down ZBTB16-down|ITGB8-up FZD5-down|IGF1-up MCL1-down|IGF1-up THBS1-down|ITGA10-down LAMA3-down|ITGB4-up JUN-down|ITGB4-up MMP1-up|ITGB4-up MMP2-up|ITGB8-up TGFB3-up|MCL1-down JUN-down|MYB-up JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|MCL1-down MMP1-up|MCL1-down MMP2-up|MCL1-down PDGFRA-down|MCL1-down ZBTB16-down|MYB-up MMP1-up|SPP1-up MMP1-up|THBS1-down MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|MYB-up MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|MYB-up TCF7L2-up|MYB-up ZBTB16-down|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down ZBTB16-down	CCND1-up_595 FLT1-down_2321|CCND1-up_595 MCL1-down_4170|CCND1-up_595 THBS1-down_7057|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HHIP-down_64399|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 TCF7L2-up_6934|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 ZBTB16-down_7704|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 TCF7L2-up_6934|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 EDNRB-down_1910|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 TGFB3-up_7043|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 IGF1-up_3479|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP1-up_4312|COMP-up_1311 MMP2-up_4313|COMP-up_1311 TGFB3-up_7043|FLT1-down_2321 CXCL12-up_6387|MCL1-down_4170 CXCL12-up_6387|MYB-up_4602 CXCL12-up_6387|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|PRKAA2-up_5563 DAPK2-down_23604|FLT1-down_2321 EDNRB-down_1910|MCL1-down_4170 EDNRB-down_1910|SPP1-up_6696 EDNRB-down_1910|THBS1-down_7057 EDNRB-down_1910|TNC-up_3371 EDNRB-down_1910|FGF14-up_2259 FLT1-down_2321|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 ZBTB16-down_7704|ITGB8-up_3696 FZD5-down_7855|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 THBS1-down_7057|ITGA10-down_8515 LAMA3-down_3909|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP1-up_4312|ITGB4-up_3691 MMP2-up_4313|ITGB8-up_3696 TGFB3-up_7043|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|MCL1-down_4170 MMP1-up_4312|MCL1-down_4170 MMP2-up_4313|MCL1-down_4170 PDGFRA-down_5156|MCL1-down_4170 ZBTB16-down_7704|MYB-up_4602 MMP1-up_4312|SPP1-up_6696 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|MYB-up_4602 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|MYB-up_4602 TCF7L2-up_6934|MYB-up_4602 ZBTB16-down_7704|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 ZBTB16-down_7704
hsa04151	hsa05202	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.032	CCND1-up CCND2-up|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up JAK1-down|CCND2-up MCL1-down|CCND2-up PDGFRA-down|CCND2-up THBS1-down|COL1A1-up IGF1-up|COL1A1-up PLAU-up|COL1A1-up PROM1-up|COL1A1-up SIX1-up|COL1A1-up ZBTB16-down|COL1A2-up IGF1-up|COL1A2-up PLAU-up|COL6A1-up ZBTB16-down|COL6A3-up PLAU-up|COMP-up IGF1-up|FIGF-down FLT1-down|FIGF-down IGF1-up|FIGF-down PLAU-up|FIGF-down PROM1-up|IGF1-up JAK1-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|SPP1-up IL1R2-down|ITGB4-up PLAU-up|ITGB4-up PROM1-up|JAK1-down PLAU-up|JAK1-down ZBTB16-down|LAMA3-down PLAU-up|MCL1-down NFKBIZ-down|MCL1-down PROM1-up|MCL1-down ZBTB16-down|MYB-up NFKBIZ-down|MYB-up PROM1-up|MYB-up SIX1-up|MYB-up ZBTB16-down|PDGFRA-down PLAU-up|PDGFRA-down PROM1-up|PDGFRA-down ZBTB16-down|SPP1-up PLAU-up|THBS1-down PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up|THBS1-down PROM1-up|TNC-up PROM1-up|THBS1-down ZBTB16-down	CCND1-up_595 CCND2-up_894|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 JAK1-down_3716|CCND2-up_894 MCL1-down_4170|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 THBS1-down_7057|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 PROM1-up_8842|COL1A1-up_1277 SIX1-up_6495|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 PLAU-up_5328|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 IGF1-up_3479|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 PROM1-up_8842|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|SPP1-up_6696 IL1R2-down_7850|ITGB4-up_3691 PLAU-up_5328|ITGB4-up_3691 PROM1-up_8842|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|LAMA3-down_3909 PLAU-up_5328|MCL1-down_4170 NFKBIZ-down_64332|MCL1-down_4170 PROM1-up_8842|MCL1-down_4170 ZBTB16-down_7704|MYB-up_4602 NFKBIZ-down_64332|MYB-up_4602 PROM1-up_8842|MYB-up_4602 SIX1-up_6495|MYB-up_4602 ZBTB16-down_7704|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 PROM1-up_8842|PDGFRA-down_5156 ZBTB16-down_7704|SPP1-up_6696 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328|THBS1-down_7057 PROM1-up_8842|TNC-up_3371 PROM1-up_8842|THBS1-down_7057 ZBTB16-down_7704
hsa04151	hsa05205	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	FLT1-down ANK2-up|PDGFRA-down ANK2-up|ITGB4-up CAV2-down|ITGB8-up CAV2-down|LAMA3-down CAV2-down|CCND1-up CSF3R-down|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up MCL1-down|CCND1-up PDGFRA-down|CCND2-up FZD5-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|COL1A1-up IGF1-up|COL1A1-up MMP2-up|COL1A1-up PLAU-up|COL1A2-up IGF1-up|COL1A2-up MMP2-up|COL1A2-up PLAU-up|COL6A1-up MMP2-up|COL6A3-up MMP2-up|COL6A3-up PLAU-up|COMP-up IGF1-up|COMP-up MMP2-up|FGF14-up FZD5-down|FIGF-down HBEGF-down|FIGF-down IGF1-up|FIGF-down MMP2-up|FIGF-down PLAU-up|FIGF-down THBS1-down|ITGB4-up FLNC-up|ITGB8-up FLNC-up|MYB-up FLNC-up|TNC-up FLNC-up|FLT1-down FZD5-down|FLT1-down HBEGF-down|FLT1-down IGF1-up|FLT1-down MMP2-up|FLT1-down PLAU-up|FLT1-down THBS1-down|ITGB8-up FZD5-down|PDGFRA-down FZD5-down|LAMA3-down HBEGF-down|MCL1-down HBEGF-down|PDGFRA-down HBEGF-down|SPP1-up HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|IGF1-up JAK1-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|ITGB4-up MMP2-up|ITGB4-up PLAU-up|JAK1-down MMP2-up|JAK1-down PLAU-up|LAMA3-down MMP2-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|MCL1-down MMP2-up|MCL1-down THBS1-down|MYB-up MMP2-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|PDGFRA-down PLAU-up|PDGFRA-down THBS1-down|SPP1-up PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up	FLT1-down_2321 ANK2-up_287|PDGFRA-down_5156 ANK2-up_287|ITGB4-up_3691 CAV2-down_858|ITGB8-up_3696 CAV2-down_858|LAMA3-down_3909 CAV2-down_858|CCND1-up_595 CSF3R-down_1441|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 MCL1-down_4170|CCND1-up_595 PDGFRA-down_5156|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PLAU-up_5328|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PLAU-up_5328|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 IGF1-up_3479|COMP-up_1311 MMP2-up_4313|FGF14-up_2259 FZD5-down_7855|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|ITGB4-up_3691 FLNC-up_2318|ITGB8-up_3696 FLNC-up_2318|MYB-up_4602 FLNC-up_2318|TNC-up_3371 FLNC-up_2318|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 THBS1-down_7057|ITGB8-up_3696 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|LAMA3-down_3909 HBEGF-down_1839|MCL1-down_4170 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 PLAU-up_5328|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|MCL1-down_4170 MMP2-up_4313|MCL1-down_4170 THBS1-down_7057|MYB-up_4602 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 THBS1-down_7057|SPP1-up_6696 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328
hsa04151	hsa05206	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CCND1-up CSF3R-down|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND2-up FLT1-down|CCND2-up JAK1-down|COL1A1-up CYP24A1-up|COL1A1-up HMOX1-down|COL1A1-up MMP16-up|COL1A1-up PLAU-up|COL1A1-up SOX4-up|COL1A1-up TNC-up|COL1A2-up HMOX1-down|COL1A2-up MMP16-up|COL1A2-up PLAU-up|COL1A2-up TNC-up|COL6A1-up HMOX1-down|COL6A1-up MMP16-up|COL6A1-up TNC-up|COL6A3-up PLAU-up|COL6A3-up TNC-up|COMP-up MMP16-up|COMP-up TNC-up|IGF1-up CYP24A1-up|SPP1-up CYP24A1-up|FIGF-down HMOX1-down|FIGF-down PDGFRA-down|FIGF-down PLAU-up|FIGF-down THBS1-down|FIGF-down TNC-up|FLT1-down HMOX1-down|FLT1-down IRS2-down|FLT1-down MCL1-down|FLT1-down MMP16-up|FLT1-down PDGFRA-down|FLT1-down PLAU-up|FLT1-down SERPINB5-up|FLT1-down THBS1-down|FLT1-down TNC-up|FLT1-down TP63-up|IGF1-up HMOX1-down|JAK1-down HMOX1-down|MYB-up HMOX1-down|SPP1-up HMOX1-down|IGF1-up IRS2-down|IGF1-up TNC-up|JAK1-down IRS2-down|MYB-up IRS2-down|PRKAA2-up IRS2-down|SPP1-up IRS2-down|ITGB4-up PLAU-up|ITGB4-up SERPINB5-up|ITGB4-up TNC-up|ITGB8-up TNC-up|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|LAMA3-down TNC-up|THBS2-up MMP16-up|MYB-up SERPINB5-up|MYB-up SOX4-up|MYB-up TNC-up|MYB-up TP63-up|SPP1-up PLAU-up|THBS2-up PLAU-up|SPP1-up SERPINB5-up|THBS2-up SERPINB5-up|SPP1-up TNC-up|SPP1-up TP63-up|THBS2-up TNC-up	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JAK1-down_3716|COL1A1-up_1277 CYP24A1-up_1591|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 MMP16-up_4325|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SOX4-up_6659|COL1A1-up_1277 TNC-up_3371|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 MMP16-up_4325|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 TNC-up_3371|COL6A1-up_1291 HMOX1-down_3162|COL6A1-up_1291 MMP16-up_4325|COL6A1-up_1291 TNC-up_3371|COL6A3-up_1293 PLAU-up_5328|COL6A3-up_1293 TNC-up_3371|COMP-up_1311 MMP16-up_4325|COMP-up_1311 TNC-up_3371|IGF1-up_3479 CYP24A1-up_1591|SPP1-up_6696 CYP24A1-up_1591|FIGF-down_2277 HMOX1-down_3162|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 TNC-up_3371|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 MMP16-up_4325|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 TNC-up_3371|FLT1-down_2321 TP63-up_8626|IGF1-up_3479 HMOX1-down_3162|JAK1-down_3716 HMOX1-down_3162|MYB-up_4602 HMOX1-down_3162|SPP1-up_6696 HMOX1-down_3162|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 TNC-up_3371|JAK1-down_3716 IRS2-down_8660|MYB-up_4602 IRS2-down_8660|PRKAA2-up_5563 IRS2-down_8660|SPP1-up_6696 IRS2-down_8660|ITGB4-up_3691 PLAU-up_5328|ITGB4-up_3691 SERPINB5-up_5268|ITGB4-up_3691 TNC-up_3371|ITGB8-up_3696 TNC-up_3371|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|LAMA3-down_3909 TNC-up_3371|THBS2-up_7058 MMP16-up_4325|MYB-up_4602 SERPINB5-up_5268|MYB-up_4602 SOX4-up_6659|MYB-up_4602 TNC-up_3371|MYB-up_4602 TP63-up_8626|SPP1-up_6696 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|SPP1-up_6696 SERPINB5-up_5268|THBS2-up_7058 SERPINB5-up_5268|SPP1-up_6696 TNC-up_3371|SPP1-up_6696 TP63-up_8626|THBS2-up_7058 TNC-up_3371
hsa04151	hsa05219	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCND1-up CSF3R-down|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up MCL1-down|CCND1-up PDGFRA-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COMP-up MMP1-up|COMP-up MMP2-up|PRKAA2-up DAPK2-down|FIGF-down HBEGF-down|FIGF-down MMP1-up|FIGF-down MMP2-up|FIGF-down THBS1-down|FLT1-down HBEGF-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down THBS1-down|IGF1-up HBEGF-down|LAMA3-down HBEGF-down|MCL1-down HBEGF-down|PDGFRA-down HBEGF-down|SPP1-up HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|IGF1-up MMP1-up|IGF1-up MMP2-up|ITGB4-up MMP1-up|ITGB4-up MMP2-up|JAK1-down MMP1-up|JAK1-down MMP2-up|LAMA3-down MMP1-up|LAMA3-down MMP2-up|LAMA3-down THBS1-down|MCL1-down MMP1-up|MCL1-down MMP2-up|MCL1-down THBS1-down|MYB-up MMP1-up|PDGFRA-down MMP1-up|SPP1-up MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|MYB-up MMP2-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|PDGFRA-down THBS1-down	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 MCL1-down_4170|CCND1-up_595 PDGFRA-down_5156|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 MMP1-up_4312|COMP-up_1311 MMP2-up_4313|PRKAA2-up_5563 DAPK2-down_23604|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|MCL1-down_4170 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|ITGB4-up_3691 MMP1-up_4312|ITGB4-up_3691 MMP2-up_4313|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|LAMA3-down_3909 MMP1-up_4312|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 THBS1-down_7057|MCL1-down_4170 MMP1-up_4312|MCL1-down_4170 MMP2-up_4313|MCL1-down_4170 THBS1-down_7057|MYB-up_4602 MMP1-up_4312|PDGFRA-down_5156 MMP1-up_4312|SPP1-up_6696 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|MYB-up_4602 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057
hsa04151	hsa05323	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|COL1A1-up CTSK-up|COL1A1-up CXCL12-up|COL1A1-up JUN-down|COL1A1-up MMP1-up|COL1A1-up TGFB3-up|COL1A2-up CTSK-up|COL1A2-up CXCL12-up|COL1A2-up JUN-down|COL1A2-up MMP1-up|COL1A2-up TGFB3-up|COL6A1-up CTSK-up|COL6A1-up JUN-down|COL6A1-up MMP1-up|COL6A1-up TGFB3-up|COL6A3-up CTSK-up|COL6A3-up JUN-down|COL6A3-up MMP1-up|COL6A3-up TGFB3-up|COMP-up CTSK-up|COMP-up CXCL12-up|COMP-up JUN-down|COMP-up MMP1-up|COMP-up TGFB3-up|CSF3R-down CXCL12-up|CSF3R-down JUN-down|IGF1-up CTSK-up|MCL1-down CTSK-up|SPP1-up CTSK-up|THBS1-down CTSK-up|THBS2-up CTSK-up|TNC-up CTSK-up|FIGF-down CXCL12-up|IGF1-up CXCL12-up|JAK1-down CXCL12-up|MCL1-down CXCL12-up|MYB-up CXCL12-up|PDGFRA-down CXCL12-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|FGF14-up TGFB3-up|FIGF-down FLT1-down|FIGF-down JUN-down|FIGF-down MMP1-up|FIGF-down TGFB3-up|IGF1-up JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|ITGB4-up JUN-down|ITGB4-up MMP1-up|ITGB8-up TGFB3-up|JAK1-down JUN-down|JAK1-down MMP1-up|LAMA3-down JUN-down|MCL1-down JUN-down|MYB-up JUN-down|PDGFRA-down JUN-down|PRKAA2-up JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down MMP1-up|MCL1-down MMP1-up|MYB-up MMP1-up|PDGFRA-down MMP1-up|SPP1-up MMP1-up|THBS1-down MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 CTSK-up_1513|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 CTSK-up_1513|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 CTSK-up_1513|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 CTSK-up_1513|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 CTSK-up_1513|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP1-up_4312|COMP-up_1311 TGFB3-up_7043|CSF3R-down_1441 CXCL12-up_6387|CSF3R-down_1441 JUN-down_3725|IGF1-up_3479 CTSK-up_1513|MCL1-down_4170 CTSK-up_1513|SPP1-up_6696 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|THBS2-up_7058 CTSK-up_1513|TNC-up_3371 CTSK-up_1513|FIGF-down_2277 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|JAK1-down_3716 CXCL12-up_6387|MCL1-down_4170 CXCL12-up_6387|MYB-up_4602 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 TGFB3-up_7043|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP1-up_4312|ITGB8-up_3696 TGFB3-up_7043|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP1-up_4312|LAMA3-down_3909 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MYB-up_4602 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 MMP1-up_4312|MCL1-down_4170 MMP1-up_4312|MYB-up_4602 MMP1-up_4312|PDGFRA-down_5156 MMP1-up_4312|SPP1-up_6696 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04151	hsa05410	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COMP-up IGF1-up|COMP-up ITGB4-up|COMP-up ITGB8-up|COMP-up TGFB3-up|FGF14-up TGFB3-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|IGF1-up JAK1-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|ITGB4-up LAMA3-down|ITGB4-up MCL1-down|ITGB4-up PDGFRA-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up MCL1-down|ITGB8-up THBS1-down|MCL1-down PRKAA2-up|MYB-up TTN-down|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|SPP1-up TTN-down|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|TNC-up TNNC1-down	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COMP-up_1311 IGF1-up_3479|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|COMP-up_1311 TGFB3-up_7043|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 MCL1-down_4170|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 MCL1-down_4170|ITGB8-up_3696 THBS1-down_7057|MCL1-down_4170 PRKAA2-up_5563|MYB-up_4602 TTN-down_7273|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa04151	hsa05412	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|COL1A1-up CDH2-up|COL1A2-up CDH2-up|COMP-up CDH2-up|FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|JAK1-down CDH2-up|MCL1-down CDH2-up|MYB-up CDH2-up|PDGFRA-down CDH2-up|SPP1-up CDH2-up|THBS1-down CDH2-up|THBS2-up CDH2-up|TNC-up CDH2-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TCF7L2-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COMP-up ITGB4-up|COMP-up ITGB8-up|FGF14-up TCF7L2-up|FLT1-down ITGB4-up|IGF1-up TCF7L2-up|ITGB4-up LAMA3-down|ITGB4-up MCL1-down|ITGB4-up PDGFRA-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up MCL1-down|ITGB8-up THBS1-down|MYB-up TCF7L2-up|PDGFRA-down TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COMP-up_1311 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|MCL1-down_4170 CDH2-up_1000|MYB-up_4602 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|SPP1-up_6696 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS2-up_7058 CDH2-up_1000|TNC-up_3371 CDH2-up_1000|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TCF7L2-up_6934|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|FGF14-up_2259 TCF7L2-up_6934|FLT1-down_2321 ITGB4-up_3691|IGF1-up_3479 TCF7L2-up_6934|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 MCL1-down_4170|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 MCL1-down_4170|ITGB8-up_3696 THBS1-down_7057|MYB-up_4602 TCF7L2-up_6934|PDGFRA-down_5156 TCF7L2-up_6934
hsa04151	hsa05414	PI3K-Akt signaling pathway - Homo sapiens (human)	CSF3R,FIGF,FLT1,ITGA10,JAK1,LAMA3,MCL1,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FGF14,IGF1,ITGB4,ITGB8,MYB,PRKAA2,SPP1,THBS2,TNC	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	FLT1-down ADRB1-down|MCL1-down ADRB1-down|MYB-up ADRB1-down|SPP1-up ADRB1-down|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up PLN-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COMP-up IGF1-up|COMP-up ITGB4-up|COMP-up ITGB8-up|COMP-up PLN-up|COMP-up TGFB3-up|FGF14-up TGFB3-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|IGF1-up JAK1-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|ITGB4-up LAMA3-down|ITGB4-up MCL1-down|ITGB4-up PDGFRA-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up MCL1-down|ITGB8-up THBS1-down|MYB-up TTN-down|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|SPP1-up TTN-down|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|TNC-up TNNC1-down	FLT1-down_2321 ADRB1-down_153|MCL1-down_4170 ADRB1-down_153|MYB-up_4602 ADRB1-down_153|SPP1-up_6696 ADRB1-down_153|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 PLN-up_5350|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COMP-up_1311 IGF1-up_3479|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|COMP-up_1311 PLN-up_5350|COMP-up_1311 TGFB3-up_7043|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 MCL1-down_4170|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 MCL1-down_4170|ITGB8-up_3696 THBS1-down_7057|MYB-up_4602 TTN-down_7273|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa04152	hsa04310	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0.009	CCND1-up FASN-down|CCND1-up HMGCR-down|CCND1-up IRS2-down|CCND1-up SCD-down|IGF1-up CCND2-up|IRS2-down CCND2-up|PRKAA2-up CCND2-up|FASN-down JUN-down|HMGCR-down JUN-down|IGF1-up JUN-down|IGF1-up MMP7-up|IGF1-up SERPINF1-up|IGF1-up SFRP2-up|IGF1-up SFRP4-up|IGF1-up TCF7L2-up|IRS2-down JUN-down|IRS2-down TCF7L2-up|PRKAA2-up JUN-down|SCD-down JUN-down	CCND1-up_595 FASN-down_2194|CCND1-up_595 HMGCR-down_3156|CCND1-up_595 IRS2-down_8660|CCND1-up_595 SCD-down_6319|IGF1-up_3479 CCND2-up_894|IRS2-down_8660 CCND2-up_894|PRKAA2-up_5563 CCND2-up_894|FASN-down_2194 JUN-down_3725|HMGCR-down_3156 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP7-up_4316|IGF1-up_3479 SERPINF1-up_5176|IGF1-up_3479 SFRP2-up_6423|IGF1-up_3479 SFRP4-up_6424|IGF1-up_3479 TCF7L2-up_6934|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 TCF7L2-up_6934|PRKAA2-up_5563 JUN-down_3725|SCD-down_6319 JUN-down_3725
hsa04152	hsa04350	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0.025	CCND1-up ID1-down|CCND1-up SMAD6-down|CCND1-up TGFB3-up|CCND1-up THBS1-down|FASN-down THBS1-down|HMGCR-down THBS1-down|IGF1-up ID1-down|IGF1-up SMAD6-down|IGF1-up TGFB3-up|IGF1-up THBS1-down|SCD-down THBS1-down	CCND1-up_595 ID1-down_3397|CCND1-up_595 SMAD6-down_4091|CCND1-up_595 TGFB3-up_7043|CCND1-up_595 THBS1-down_7057|FASN-down_2194 THBS1-down_7057|HMGCR-down_3156 THBS1-down_7057|IGF1-up_3479 ID1-down_3397|IGF1-up_3479 SMAD6-down_4091|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 THBS1-down_7057|SCD-down_6319 THBS1-down_7057
hsa04152	hsa04380	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0.004	CCND1-up CTSK-up|CCND1-up FHL2-up|CCND1-up FOSL2-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|IGF1-up CTSK-up|FASN-down JUN-down|FASN-down SOCS3-down|IGF1-up FHL2-up|IGF1-up FOSL2-down|HMGCR-down JUN-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|SCD-down JUN-down|SCD-down SOCS3-down	CCND1-up_595 CTSK-up_1513|CCND1-up_595 FHL2-up_2274|CCND1-up_595 FOSL2-down_2355|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|IGF1-up_3479 CTSK-up_1513|FASN-down_2194 JUN-down_3725|FASN-down_2194 SOCS3-down_9021|IGF1-up_3479 FHL2-up_2274|IGF1-up_3479 FOSL2-down_2355|HMGCR-down_3156 JUN-down_3725|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|SCD-down_6319 JUN-down_3725|SCD-down_6319 SOCS3-down_9021
hsa04152	hsa04390	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.011	CCND1-up FASN-down|CCND1-up HMGCR-down|CCND1-up IRS2-down|CCND1-up SCD-down|IGF1-up CCND2-up|IRS2-down CCND2-up|PRKAA2-up CCND2-up|FASN-down SERPINE1-down|HMGCR-down SERPINE1-down|IGF1-up ID1-down|IGF1-up SERPINE1-down|IGF1-up SOX2-up|IGF1-up TCF7L2-up|IGF1-up TGFB3-up|IRS2-down SERPINE1-down|IRS2-down TCF7L2-up|SCD-down SERPINE1-down	CCND1-up_595 FASN-down_2194|CCND1-up_595 HMGCR-down_3156|CCND1-up_595 IRS2-down_8660|CCND1-up_595 SCD-down_6319|IGF1-up_3479 CCND2-up_894|IRS2-down_8660 CCND2-up_894|PRKAA2-up_5563 CCND2-up_894|FASN-down_2194 SERPINE1-down_5054|HMGCR-down_3156 SERPINE1-down_5054|IGF1-up_3479 ID1-down_3397|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 SOX2-up_6657|IGF1-up_3479 TCF7L2-up_6934|IGF1-up_3479 TGFB3-up_7043|IRS2-down_8660 SERPINE1-down_5054|IRS2-down_8660 TCF7L2-up_6934|SCD-down_6319 SERPINE1-down_5054
hsa04152	hsa04512	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0.01	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up ITGB4-up|CCND1-up LAMA3-down|CCND1-up SPP1-up|CCND1-up THBS1-down|CCND1-up THBS2-up|CCND1-up TNC-up|IGF1-up COL1A1-up|IGF1-up COL1A2-up|IGF1-up COMP-up|FASN-down ITGB4-up|FASN-down SPP1-up|FASN-down THBS1-down|HMGCR-down THBS1-down|IGF1-up SPP1-up|IGF1-up THBS1-down|IGF1-up THBS2-up|IGF1-up TNC-up|IRS2-down SPP1-up|SCD-down SPP1-up|SCD-down THBS1-down	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 SPP1-up_6696|CCND1-up_595 THBS1-down_7057|CCND1-up_595 THBS2-up_7058|CCND1-up_595 TNC-up_3371|IGF1-up_3479 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|IGF1-up_3479 COMP-up_1311|FASN-down_2194 ITGB4-up_3691|FASN-down_2194 SPP1-up_6696|FASN-down_2194 THBS1-down_7057|HMGCR-down_3156 THBS1-down_7057|IGF1-up_3479 SPP1-up_6696|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 THBS2-up_7058|IGF1-up_3479 TNC-up_3371|IRS2-down_8660 SPP1-up_6696|SCD-down_6319 SPP1-up_6696|SCD-down_6319 THBS1-down_7057
hsa04152	hsa04514	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0.047	CCND1-up CD274-down|CCND1-up CDH2-up|CCND1-up CDH3-up|CCND1-up NCAM1-up|CCND1-up VCAM1-up|IGF1-up CD274-down|IGF1-up CDH2-up|IGF1-up CLDN5-down|FASN-down VCAM1-up|HMGCR-down VCAM1-up|IGF1-up NCAM1-up|IGF1-up SELL-down|IGF1-up VCAM1-up	CCND1-up_595 CD274-down_29126|CCND1-up_595 CDH2-up_1000|CCND1-up_595 CDH3-up_1001|CCND1-up_595 NCAM1-up_4684|CCND1-up_595 VCAM1-up_7412|IGF1-up_3479 CD274-down_29126|IGF1-up_3479 CDH2-up_1000|IGF1-up_3479 CLDN5-down_7122|FASN-down_2194 VCAM1-up_7412|HMGCR-down_3156 VCAM1-up_7412|IGF1-up_3479 NCAM1-up_4684|IGF1-up_3479 SELL-down_6402|IGF1-up_3479 VCAM1-up_7412
hsa04152	hsa04610	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.021	CCND1-up CFH-up|CCND1-up PLAU-up|CCND1-up SERPINE1-down|IGF1-up CFH-up|IGF1-up F3-down|FASN-down SERPINE1-down|HMGCR-down PLAU-up|HMGCR-down SERPINE1-down|HMGCR-down TFPI-down|IGF1-up SERPINE1-down|IRS2-down SERPINE1-down|SCD-down SERPINE1-down	CCND1-up_595 CFH-up_3075|CCND1-up_595 PLAU-up_5328|CCND1-up_595 SERPINE1-down_5054|IGF1-up_3479 CFH-up_3075|IGF1-up_3479 F3-down_2152|FASN-down_2194 SERPINE1-down_5054|HMGCR-down_3156 PLAU-up_5328|HMGCR-down_3156 SERPINE1-down_5054|HMGCR-down_3156 TFPI-down_7035|IGF1-up_3479 SERPINE1-down_5054|IRS2-down_8660 SERPINE1-down_5054|SCD-down_6319 SERPINE1-down_5054
hsa04152	hsa04668	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	CCND1-up JUN-down|CCND1-up MAP3K8-down|CCND1-up SOCS3-down|CCND1-up VCAM1-up|IGF1-up CXCL2-down|IRS2-down CXCL2-down|SCD-down CXCL2-down|FASN-down JUN-down|FASN-down SOCS3-down|FASN-down VCAM1-up|HMGCR-down JUN-down|HMGCR-down VCAM1-up|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|SCD-down JUN-down|PRKAA2-up MAP3K8-down|SCD-down SOCS3-down	CCND1-up_595 JUN-down_3725|CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 SOCS3-down_9021|CCND1-up_595 VCAM1-up_7412|IGF1-up_3479 CXCL2-down_2920|IRS2-down_8660 CXCL2-down_2920|SCD-down_6319 CXCL2-down_2920|FASN-down_2194 JUN-down_3725|FASN-down_2194 SOCS3-down_9021|FASN-down_2194 VCAM1-up_7412|HMGCR-down_3156 JUN-down_3725|HMGCR-down_3156 VCAM1-up_7412|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|SCD-down_6319 JUN-down_3725|PRKAA2-up_5563 MAP3K8-down_1326|SCD-down_6319 SOCS3-down_9021
hsa04152	hsa04670	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0.046	CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|IGF1-up CLDN5-down|HMGCR-down CXCL12-up|IGF1-up CXCL12-up|FASN-down MMP2-up|FASN-down VCAM1-up|HMGCR-down MMP2-up|HMGCR-down VCAM1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up	CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|IGF1-up_3479 CLDN5-down_7122|HMGCR-down_3156 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|FASN-down_2194 MMP2-up_4313|FASN-down_2194 VCAM1-up_7412|HMGCR-down_3156 MMP2-up_4313|HMGCR-down_3156 VCAM1-up_7412|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412
hsa04152	hsa04933	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.01	CCND1-up FASN-down|CCND1-up HMGCR-down|CCND1-up IRS2-down|CCND1-up SCD-down|IGF1-up COL1A1-up|IGF1-up COL1A2-up|IGF1-up COL3A1-up|IGF1-up F3-down|FASN-down JUN-down|FASN-down MMP2-up|FASN-down SERPINE1-down|FASN-down VCAM1-up|IGF1-up FIGF-down|HMGCR-down JUN-down|HMGCR-down MMP2-up|HMGCR-down SERPINE1-down|HMGCR-down VCAM1-up|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|IRS2-down JUN-down|IRS2-down SERPINE1-down|PRKAA2-up JUN-down|SCD-down JUN-down|SCD-down SERPINE1-down	CCND1-up_595 FASN-down_2194|CCND1-up_595 HMGCR-down_3156|CCND1-up_595 IRS2-down_8660|CCND1-up_595 SCD-down_6319|IGF1-up_3479 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|IGF1-up_3479 COL3A1-up_1281|IGF1-up_3479 F3-down_2152|FASN-down_2194 JUN-down_3725|FASN-down_2194 MMP2-up_4313|FASN-down_2194 SERPINE1-down_5054|FASN-down_2194 VCAM1-up_7412|IGF1-up_3479 FIGF-down_2277|HMGCR-down_3156 JUN-down_3725|HMGCR-down_3156 MMP2-up_4313|HMGCR-down_3156 SERPINE1-down_5054|HMGCR-down_3156 VCAM1-up_7412|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SERPINE1-down_5054|PRKAA2-up_5563 JUN-down_3725|SCD-down_6319 JUN-down_3725|SCD-down_6319 SERPINE1-down_5054
hsa04152	hsa04978	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.044	CCND1-up HMOX1-down|CCND1-up TF-up|FASN-down HMOX1-down|FASN-down TF-up|HMGCR-down HMOX1-down|HMGCR-down TF-up|IGF1-up HMOX1-down|IRS2-down HMOX1-down|SCD-down HMOX1-down|IGF1-up TF-up|SCD-down TF-up	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|FASN-down_2194 HMOX1-down_3162|FASN-down_2194 TF-up_7018|HMGCR-down_3156 HMOX1-down_3162|HMGCR-down_3156 TF-up_7018|IGF1-up_3479 HMOX1-down_3162|IRS2-down_8660 HMOX1-down_3162|SCD-down_6319 HMOX1-down_3162|IGF1-up_3479 TF-up_7018|SCD-down_6319 TF-up_7018
hsa04152	hsa05145	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.013	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up LDLR-down|CCND1-up TGFB3-up|FASN-down LDLR-down|HMGCR-down LDLR-down|IGF1-up HSPA1A-down|PFKFB2-down HSPA1A-down|PFKFB2-down HSPA1B-down|IGF1-up JAK1-down|IGF1-up LDLR-down|IGF1-up TGFB3-up|IRS2-down JAK1-down|IRS2-down LDLR-down|SCD-down LDLR-down	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 LDLR-down_3949|CCND1-up_595 TGFB3-up_7043|FASN-down_2194 LDLR-down_3949|HMGCR-down_3156 LDLR-down_3949|IGF1-up_3479 HSPA1A-down_3303|PFKFB2-down_5208 HSPA1A-down_3303|PFKFB2-down_5208 HSPA1B-down_3304|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 TGFB3-up_7043|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 LDLR-down_3949|SCD-down_6319 LDLR-down_3949
hsa04152	hsa05164	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0.04	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|FASN-down JUN-down|FASN-down SOCS3-down|HMGCR-down JUN-down|IGF1-up HSPA1A-down|PFKFB2-down HSPA1A-down|PFKFB2-down HSPA1B-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PRSS1-up|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|SCD-down JUN-down|SCD-down SOCS3-down	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|FASN-down_2194 JUN-down_3725|FASN-down_2194 SOCS3-down_9021|HMGCR-down_3156 JUN-down_3725|IGF1-up_3479 HSPA1A-down_3303|PFKFB2-down_5208 HSPA1A-down_3303|PFKFB2-down_5208 HSPA1B-down_3304|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|SCD-down_6319 JUN-down_3725|SCD-down_6319 SOCS3-down_9021
hsa04152	hsa05168	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.007	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up SOCS3-down|IGF1-up CD74-up|SCD-down CD74-up|FASN-down JUN-down|FASN-down SOCS3-down|HMGCR-down JUN-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|SCD-down JUN-down|SCD-down SOCS3-down	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 SOCS3-down_9021|IGF1-up_3479 CD74-up_972|SCD-down_6319 CD74-up_972|FASN-down_2194 JUN-down_3725|FASN-down_2194 SOCS3-down_9021|HMGCR-down_3156 JUN-down_3725|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|SCD-down_6319 JUN-down_3725|SCD-down_6319 SOCS3-down_9021
hsa04152	hsa05202	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.011	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|IRS2-down CCND2-up|PRKAA2-up CCND2-up|FASN-down FLT1-down|FASN-down IGF1-up|HMGCR-down FLT1-down|IRS2-down FLT1-down|HMGCR-down IGF1-up|HMGCR-down PLAU-up|HMGCR-down PROM1-up|HMGCR-down SIX1-up|HMGCR-down SIX4-up|IGF1-up IRS2-down|IGF1-up SCD-down|IRS2-down SIX1-up	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|IRS2-down_8660 CCND2-up_894|PRKAA2-up_5563 CCND2-up_894|FASN-down_2194 FLT1-down_2321|FASN-down_2194 IGF1-up_3479|HMGCR-down_3156 FLT1-down_2321|IRS2-down_8660 FLT1-down_2321|HMGCR-down_3156 IGF1-up_3479|HMGCR-down_3156 PLAU-up_5328|HMGCR-down_3156 PROM1-up_8842|HMGCR-down_3156 SIX1-up_6495|HMGCR-down_3156 SIX4-up_51804|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 SCD-down_6319|IRS2-down_8660 SIX1-up_6495
hsa04152	hsa05206	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.013	CCND1-up FASN-down|CCND1-up HMGCR-down|CCND1-up SCD-down|IGF1-up CCND2-up|PRKAA2-up CCND2-up|FASN-down CYP24A1-up|IGF1-up CYP24A1-up|SCD-down CYP24A1-up|FASN-down HMOX1-down|FASN-down IRS2-down|FASN-down THBS1-down|FASN-down TP63-up|HMGCR-down HMOX1-down|HMGCR-down IRS2-down|HMGCR-down PLAU-up|HMGCR-down THBS1-down|IGF1-up HMOX1-down|SCD-down HMOX1-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|IGF1-up TNC-up|PRKAA2-up MCL1-down|SCD-down THBS1-down	CCND1-up_595 FASN-down_2194|CCND1-up_595 HMGCR-down_3156|CCND1-up_595 SCD-down_6319|IGF1-up_3479 CCND2-up_894|PRKAA2-up_5563 CCND2-up_894|FASN-down_2194 CYP24A1-up_1591|IGF1-up_3479 CYP24A1-up_1591|SCD-down_6319 CYP24A1-up_1591|FASN-down_2194 HMOX1-down_3162|FASN-down_2194 IRS2-down_8660|FASN-down_2194 THBS1-down_7057|FASN-down_2194 TP63-up_8626|HMGCR-down_3156 HMOX1-down_3162|HMGCR-down_3156 IRS2-down_8660|HMGCR-down_3156 PLAU-up_5328|HMGCR-down_3156 THBS1-down_7057|IGF1-up_3479 HMOX1-down_3162|SCD-down_6319 HMOX1-down_3162|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 TNC-up_3371|PRKAA2-up_5563 MCL1-down_4170|SCD-down_6319 THBS1-down_7057
hsa04152	hsa05219	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.011	CCND1-up FASN-down|CCND1-up HMGCR-down|CCND1-up IRS2-down|CCND1-up SCD-down|PRKAA2-up DAPK2-down|FASN-down HBEGF-down|FASN-down MMP2-up|FASN-down THBS1-down|IGF1-up HBEGF-down|HMGCR-down MMP1-up|HMGCR-down MMP2-up|HMGCR-down THBS1-down|IGF1-up MMP1-up|IGF1-up MMP2-up|IGF1-up THBS1-down|SCD-down THBS1-down	CCND1-up_595 FASN-down_2194|CCND1-up_595 HMGCR-down_3156|CCND1-up_595 IRS2-down_8660|CCND1-up_595 SCD-down_6319|PRKAA2-up_5563 DAPK2-down_23604|FASN-down_2194 HBEGF-down_1839|FASN-down_2194 MMP2-up_4313|FASN-down_2194 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|HMGCR-down_3156 MMP1-up_4312|HMGCR-down_3156 MMP2-up_4313|HMGCR-down_3156 THBS1-down_7057|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THBS1-down_7057|SCD-down_6319 THBS1-down_7057
hsa04152	hsa05323	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.032	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|IGF1-up CTSK-up|HMGCR-down CXCL12-up|IGF1-up CXCL12-up|FASN-down FLT1-down|FASN-down JUN-down|HMGCR-down FLT1-down|IGF1-up FLT1-down|IRS2-down FLT1-down|HMGCR-down JUN-down|HMGCR-down MMP1-up|IGF1-up JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|IRS2-down JUN-down|PRKAA2-up JUN-down|SCD-down JUN-down	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|IGF1-up_3479 CTSK-up_1513|HMGCR-down_3156 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|FASN-down_2194 FLT1-down_2321|FASN-down_2194 JUN-down_3725|HMGCR-down_3156 FLT1-down_2321|IGF1-up_3479 FLT1-down_2321|IRS2-down_8660 FLT1-down_2321|HMGCR-down_3156 JUN-down_3725|HMGCR-down_3156 MMP1-up_4312|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|IRS2-down_8660 JUN-down_3725|PRKAA2-up_5563 JUN-down_3725|SCD-down_6319 JUN-down_3725
hsa04152	hsa05410	AMPK signaling pathway - Homo sapiens (human)	FASN,HMGCR,IRS2,PFKFB2,SCD,CCND1,IGF1,PRKAA2	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.043	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|FASN-down IGF1-up|FASN-down ITGB4-up|FASN-down PRKAA2-up|HMGCR-down IGF1-up|HMGCR-down PRKAA2-up|IGF1-up IRS2-down|IGF1-up SCD-down|IRS2-down PRKAA2-up|PFKFB2-down PRKAA2-up|PRKAA2-up SCD-down	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|FASN-down_2194 IGF1-up_3479|FASN-down_2194 ITGB4-up_3691|FASN-down_2194 PRKAA2-up_5563|HMGCR-down_3156 IGF1-up_3479|HMGCR-down_3156 PRKAA2-up_5563|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 SCD-down_6319|IRS2-down_8660 PRKAA2-up_5563|PFKFB2-down_5208 PRKAA2-up_5563|PRKAA2-up_5563 SCD-down_6319
hsa04213	hsa04310	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	0.022	HSPA1A-down CCND1-up|IGF1-up CCND1-up|IRS2-down CCND1-up|PRKAA2-up CCND1-up|IGF1-up CCND2-up|IRS2-down CCND2-up|PRKAA2-up CCND2-up|HSPA1A-down JUN-down|HSPA1B-down JUN-down|IGF1-up JUN-down|IGF1-up MMP7-up|IGF1-up SERPINF1-up|IGF1-up SFRP2-up|IGF1-up SFRP4-up|IGF1-up TCF7L2-up|IRS2-down JUN-down|IRS2-down TCF7L2-up|PRKAA2-up JUN-down|SOD2-down JUN-down|SOD2-down MMP7-up|SOD2-down SERPINF1-up	HSPA1A-down_3303 CCND1-up_595|IGF1-up_3479 CCND1-up_595|IRS2-down_8660 CCND1-up_595|PRKAA2-up_5563 CCND1-up_595|IGF1-up_3479 CCND2-up_894|IRS2-down_8660 CCND2-up_894|PRKAA2-up_5563 CCND2-up_894|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP7-up_4316|IGF1-up_3479 SERPINF1-up_5176|IGF1-up_3479 SFRP2-up_6423|IGF1-up_3479 SFRP4-up_6424|IGF1-up_3479 TCF7L2-up_6934|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 TCF7L2-up_6934|PRKAA2-up_5563 JUN-down_3725|SOD2-down_6648 JUN-down_3725|SOD2-down_6648 MMP7-up_4316|SOD2-down_6648 SERPINF1-up_5176
hsa04213	hsa04380	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0.046	IGF1-up CTSK-up|SOD2-down CTSK-up|IGF1-up FHL2-up|IGF1-up FOSL2-down|HSPA1A-down JAK1-down|HSPA1A-down JUN-down|HSPA1B-down JAK1-down|HSPA1B-down JUN-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|SOD2-down JUN-down|SOD2-down SOCS3-down	IGF1-up_3479 CTSK-up_1513|SOD2-down_6648 CTSK-up_1513|IGF1-up_3479 FHL2-up_2274|IGF1-up_3479 FOSL2-down_2355|HSPA1A-down_3303 JAK1-down_3716|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JAK1-down_3716|HSPA1B-down_3304 JUN-down_3725|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|SOD2-down_6648 JUN-down_3725|SOD2-down_6648 SOCS3-down_9021
hsa04213	hsa04630	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0.002	HSPA1A-down CCND1-up|IGF1-up CCND1-up|IRS2-down CCND1-up|PRKAA2-up CCND1-up|IGF1-up CCND2-up|IRS2-down CCND2-up|PRKAA2-up CCND2-up|HSPA1A-down JAK1-down|HSPA1B-down JAK1-down|IGF1-up JAK1-down|IGF1-up LIFR-down|IGF1-up MCL1-down|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down SOCS3-down|PRKAA2-up MCL1-down|SOD2-down MCL1-down|SOD2-down SOCS3-down	HSPA1A-down_3303 CCND1-up_595|IGF1-up_3479 CCND1-up_595|IRS2-down_8660 CCND1-up_595|PRKAA2-up_5563 CCND1-up_595|IGF1-up_3479 CCND2-up_894|IRS2-down_8660 CCND2-up_894|PRKAA2-up_5563 CCND2-up_894|HSPA1A-down_3303 JAK1-down_3716|HSPA1B-down_3304 JAK1-down_3716|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LIFR-down_3977|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 MCL1-down_4170|SOD2-down_6648 MCL1-down_4170|SOD2-down_6648 SOCS3-down_9021
hsa04213	hsa04668	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.015	HSPA1A-down CXCL2-down|IGF1-up CXCL2-down|IRS2-down CXCL2-down|SOD2-down CXCL2-down|HSPA1A-down JUN-down|HSPA1B-down JUN-down|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|SOD2-down JUN-down|PRKAA2-up MAP3K8-down|SOD2-down MAP3K8-down|SOD2-down SOCS3-down	HSPA1A-down_3303 CXCL2-down_2920|IGF1-up_3479 CXCL2-down_2920|IRS2-down_8660 CXCL2-down_2920|SOD2-down_6648 CXCL2-down_2920|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|SOD2-down_6648 JUN-down_3725|PRKAA2-up_5563 MAP3K8-down_1326|SOD2-down_6648 MAP3K8-down_1326|SOD2-down_6648 SOCS3-down_9021
hsa04213	hsa04933	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.047	HSPA1A-down CCND1-up|IGF1-up CCND1-up|IRS2-down CCND1-up|PRKAA2-up CCND1-up|HSPA1A-down COL1A1-up|IGF1-up COL1A1-up|IGF1-up COL1A2-up|HSPA1A-down COL3A1-up|IGF1-up COL3A1-up|HSPA1A-down F3-down|IGF1-up F3-down|SOD2-down F3-down|IGF1-up FIGF-down|HSPA1A-down JUN-down|HSPA1B-down JUN-down|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|IRS2-down JUN-down|IRS2-down SERPINE1-down|PRKAA2-up JUN-down|SOD2-down JUN-down|SOD2-down MMP2-up	HSPA1A-down_3303 CCND1-up_595|IGF1-up_3479 CCND1-up_595|IRS2-down_8660 CCND1-up_595|PRKAA2-up_5563 CCND1-up_595|HSPA1A-down_3303 COL1A1-up_1277|IGF1-up_3479 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|HSPA1A-down_3303 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|HSPA1A-down_3303 F3-down_2152|IGF1-up_3479 F3-down_2152|SOD2-down_6648 F3-down_2152|IGF1-up_3479 FIGF-down_2277|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SERPINE1-down_5054|PRKAA2-up_5563 JUN-down_3725|SOD2-down_6648 JUN-down_3725|SOD2-down_6648 MMP2-up_4313
hsa04213	hsa05168	Longevity regulating pathway - multiple species - Homo sapiens (human)	HSPA1A,HSPA1B,IRS2,SOD2,IGF1,PRKAA2	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.026	IGF1-up CD74-up|HSPA1A-down JAK1-down|HSPA1A-down JUN-down|HSPA1B-down JAK1-down|HSPA1B-down JUN-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up SOCS3-down|IRS2-down JAK1-down|IRS2-down JUN-down|IRS2-down SOCS3-down|PRKAA2-up JUN-down|SOD2-down JUN-down|SOD2-down SOCS3-down	IGF1-up_3479 CD74-up_972|HSPA1A-down_3303 JAK1-down_3716|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JAK1-down_3716|HSPA1B-down_3304 JUN-down_3725|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 SOCS3-down_9021|IRS2-down_8660 JAK1-down_3716|IRS2-down_8660 JUN-down_3725|IRS2-down_8660 SOCS3-down_9021|PRKAA2-up_5563 JUN-down_3725|SOD2-down_6648 JUN-down_3725|SOD2-down_6648 SOCS3-down_9021
hsa04270	hsa04974	Vascular smooth muscle contraction - Homo sapiens (human)	NPR1,PLA2G1B,ACTA2,ACTG2,GUCY1A3,KCNMA1,MYH11	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	ACTA2-up COL14A1-up|ACTA2-up COL18A1-up|ACTA2-up COL1A1-up|ACTA2-up COL1A2-up|ACTA2-up COL3A1-up|ACTA2-up COL5A1-up|ACTA2-up COL5A2-up|ACTA2-up COL6A1-up|ACTA2-up COL6A3-up|ACTA2-up MME-down|ACTG2-up COL14A1-up|ACTG2-up COL15A1-up|ACTG2-up COL1A1-up|ACTG2-up COL1A2-up|ACTG2-up COL3A1-up|ACTG2-up COL5A2-up|ACTG2-up COL6A3-up|KCNMA1-up COL14A1-up|MYH11-up COL14A1-up|MYH11-up COL1A1-up|MYH11-up COL1A2-up|PLA2G1B-down COL1A2-up|MYH11-up COL3A1-up|MYH11-up COL5A1-up|MYH11-up COL5A2-up|PLA2G1B-down COL5A2-up|MYH11-up COL6A3-up|MYH11-up COL7A1-up|PLA2G1B-down CPA3-up|KCNMA1-up KCNN4-up|KCNMA1-up MME-down|MYH11-up MME-down|NPR1-down MME-down|PLA2G1B-down PRSS1-up	ACTA2-up_59 COL14A1-up_7373|ACTA2-up_59 COL18A1-up_80781|ACTA2-up_59 COL1A1-up_1277|ACTA2-up_59 COL1A2-up_1278|ACTA2-up_59 COL3A1-up_1281|ACTA2-up_59 COL5A1-up_1289|ACTA2-up_59 COL5A2-up_1290|ACTA2-up_59 COL6A1-up_1291|ACTA2-up_59 COL6A3-up_1293|ACTA2-up_59 MME-down_4311|ACTG2-up_72 COL14A1-up_7373|ACTG2-up_72 COL15A1-up_1306|ACTG2-up_72 COL1A1-up_1277|ACTG2-up_72 COL1A2-up_1278|ACTG2-up_72 COL3A1-up_1281|ACTG2-up_72 COL5A2-up_1290|ACTG2-up_72 COL6A3-up_1293|KCNMA1-up_3778 COL14A1-up_7373|MYH11-up_4629 COL14A1-up_7373|MYH11-up_4629 COL1A1-up_1277|MYH11-up_4629 COL1A2-up_1278|PLA2G1B-down_5319 COL1A2-up_1278|MYH11-up_4629 COL3A1-up_1281|MYH11-up_4629 COL5A1-up_1289|MYH11-up_4629 COL5A2-up_1290|PLA2G1B-down_5319 COL5A2-up_1290|MYH11-up_4629 COL6A3-up_1293|MYH11-up_4629 COL7A1-up_1294|PLA2G1B-down_5319 CPA3-up_1359|KCNMA1-up_3778 KCNN4-up_3783|KCNMA1-up_3778 MME-down_4311|MYH11-up_4629 MME-down_4311|NPR1-down_4881 MME-down_4311|PLA2G1B-down_5319 PRSS1-up_5644
hsa04270	hsa05016	Vascular smooth muscle contraction - Homo sapiens (human)	NPR1,PLA2G1B,ACTA2,ACTG2,GUCY1A3,KCNMA1,MYH11	Huntington's disease - Homo sapiens (human)	BDNF,SOD2,DNAH11,DNAH12,DNAH3,DNAH7,DNAH9,DNAI1,DNAI2,DNALI1	0	ACTA2-up BDNF-down|ACTA2-up DNAH11-up|ACTA2-up DNAH12-up|ACTA2-up DNAH3-up|ACTA2-up DNAH7-up|ACTA2-up DNAH9-up|ACTA2-up DNALI1-up|ACTG2-up DNAH11-up|ACTG2-up DNAH12-up|ACTG2-up DNAH3-up|ACTG2-up DNAH7-up|ACTG2-up DNAH9-up|ACTG2-up DNALI1-up|KCNMA1-up BDNF-down|MYH11-up DNAH11-up|GUCY1A3-up DNAH12-up|MYH11-up DNAH12-up|MYH11-up DNAH3-up|GUCY1A3-up DNAH7-up|MYH11-up DNAH7-up|MYH11-up DNAH9-up|GUCY1A3-up SOD2-down|NPR1-down SOD2-down	ACTA2-up_59 BDNF-down_627|ACTA2-up_59 DNAH11-up_8701|ACTA2-up_59 DNAH12-up_201625|ACTA2-up_59 DNAH3-up_55567|ACTA2-up_59 DNAH7-up_56171|ACTA2-up_59 DNAH9-up_1770|ACTA2-up_59 DNALI1-up_7802|ACTG2-up_72 DNAH11-up_8701|ACTG2-up_72 DNAH12-up_201625|ACTG2-up_72 DNAH3-up_55567|ACTG2-up_72 DNAH7-up_56171|ACTG2-up_72 DNAH9-up_1770|ACTG2-up_72 DNALI1-up_7802|KCNMA1-up_3778 BDNF-down_627|MYH11-up_4629 DNAH11-up_8701|GUCY1A3-up_2982 DNAH12-up_201625|MYH11-up_4629 DNAH12-up_201625|MYH11-up_4629 DNAH3-up_55567|GUCY1A3-up_2982 DNAH7-up_56171|MYH11-up_4629 DNAH7-up_56171|MYH11-up_4629 DNAH9-up_1770|GUCY1A3-up_2982 SOD2-down_6648|NPR1-down_4881 SOD2-down_6648
hsa04270	hsa05032	Vascular smooth muscle contraction - Homo sapiens (human)	NPR1,PLA2G1B,ACTA2,ACTG2,GUCY1A3,KCNMA1,MYH11	Morphine addiction - Homo sapiens (human)	ARRB1,PDE4B,PDE4D,GABBR1,GABBR2,KCNJ5,PDE7B	0.048	ACTA2-up PDE4B-down|ACTA2-up PDE4D-down|ACTA2-up PDE7B-up|ACTG2-up PDE4B-down|ACTG2-up PDE4D-down|ACTG2-up PDE7B-up|KCNMA1-up ARRB1-down|GUCY1A3-up PDE4B-down|GUCY1A3-up PDE4D-down|GUCY1A3-up PDE7B-up|KCNMA1-up KCNJ5-up|MYH11-up PDE4B-down|MYH11-up PDE4D-down|MYH11-up PDE7B-up|NPR1-down PDE4B-down|NPR1-down PDE4D-down|NPR1-down PDE7B-up	ACTA2-up_59 PDE4B-down_5142|ACTA2-up_59 PDE4D-down_5144|ACTA2-up_59 PDE7B-up_27115|ACTG2-up_72 PDE4B-down_5142|ACTG2-up_72 PDE4D-down_5144|ACTG2-up_72 PDE7B-up_27115|KCNMA1-up_3778 ARRB1-down_408|GUCY1A3-up_2982 PDE4B-down_5142|GUCY1A3-up_2982 PDE4D-down_5144|GUCY1A3-up_2982 PDE7B-up_27115|KCNMA1-up_3778 KCNJ5-up_3762|MYH11-up_4629 PDE4B-down_5142|MYH11-up_4629 PDE4D-down_5144|MYH11-up_4629 PDE7B-up_27115|NPR1-down_4881 PDE4B-down_5142|NPR1-down_4881 PDE4D-down_5144|NPR1-down_4881 PDE7B-up_27115
hsa04270	hsa05414	Vascular smooth muscle contraction - Homo sapiens (human)	NPR1,PLA2G1B,ACTA2,ACTG2,GUCY1A3,KCNMA1,MYH11	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.043	ACTA2-up IGF1-up|ACTA2-up TGFB3-up|ACTA2-up TNNC1-down|ACTA2-up TTN-down|ACTG2-up TGFB3-up|ACTG2-up TNNC1-down|KCNMA1-up ADRB1-down|NPR1-down ADRB1-down|MYH11-up IGF1-up|PLA2G1B-down IGF1-up|KCNMA1-up PLN-up|MYH11-up PLN-up|MYH11-up TNNC1-down|MYH11-up TTN-down|NPR1-down PLN-up	ACTA2-up_59 IGF1-up_3479|ACTA2-up_59 TGFB3-up_7043|ACTA2-up_59 TNNC1-down_7134|ACTA2-up_59 TTN-down_7273|ACTG2-up_72 TGFB3-up_7043|ACTG2-up_72 TNNC1-down_7134|KCNMA1-up_3778 ADRB1-down_153|NPR1-down_4881 ADRB1-down_153|MYH11-up_4629 IGF1-up_3479|PLA2G1B-down_5319 IGF1-up_3479|KCNMA1-up_3778 PLN-up_5350|MYH11-up_4629 PLN-up_5350|MYH11-up_4629 TNNC1-down_7134|MYH11-up_4629 TTN-down_7273|NPR1-down_4881 PLN-up_5350
hsa04310	hsa04350	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	0	CCND1-up ID1-down|CCND1-up SMAD6-down|CCND1-up TGFB3-up|CCND1-up THBS1-down|CCND2-up SMAD6-down|CCND2-up TGFB3-up|CCND2-up THBS1-down|JUN-down ID1-down|SERPINF1-up ID1-down|JUN-down SMAD6-down|JUN-down TGFB3-up|JUN-down THBS1-down|SFRP4-up LTBP1-up|MMP7-up THBS1-down|SERPINF1-up THBS1-down|SFRP2-up SMAD6-down|SFRP2-up TGFB3-up|SFRP2-up THBS1-down|SFRP4-up TGFB3-up|SFRP4-up THBS1-down|TCF7L2-up SMAD6-down|TCF7L2-up TGFB3-up	CCND1-up_595 ID1-down_3397|CCND1-up_595 SMAD6-down_4091|CCND1-up_595 TGFB3-up_7043|CCND1-up_595 THBS1-down_7057|CCND2-up_894 SMAD6-down_4091|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 THBS1-down_7057|JUN-down_3725 ID1-down_3397|SERPINF1-up_5176 ID1-down_3397|JUN-down_3725 SMAD6-down_4091|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 THBS1-down_7057|SFRP4-up_6424 LTBP1-up_4052|MMP7-up_4316 THBS1-down_7057|SERPINF1-up_5176 THBS1-down_7057|SFRP2-up_6423 SMAD6-down_4091|SFRP2-up_6423 TGFB3-up_7043|SFRP2-up_6423 THBS1-down_7057|SFRP4-up_6424 TGFB3-up_7043|SFRP4-up_6424 THBS1-down_7057|TCF7L2-up_6934 SMAD6-down_4091|TCF7L2-up_6934 TGFB3-up_7043
hsa04310	hsa04360	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	0	JUN-down BOC-up|CCND1-up CXCL12-up|CCND1-up EPHA3-up|CCND2-up CXCL12-up|JUN-down CXCL12-up|MMP7-up CXCL12-up|SERPINF1-up CXCL12-up|SFRP2-up CXCL12-up|FZD5-down EPHA3-up|JUN-down EPHA3-up|SFRP2-up EPHA3-up|TCF7L2-up EPHA3-up|FZD5-down RND1-down|JUN-down NTN1-up|JUN-down RND1-down|MMP7-up NTN1-up|SERPINF1-up NTN1-up|SFRP2-up NTN1-up|SFRP4-up NTN1-up|SFRP2-up RND1-down|SFRP4-up RND1-down	JUN-down_3725 BOC-up_91653|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 EPHA3-up_2042|CCND2-up_894 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|MMP7-up_4316 CXCL12-up_6387|SERPINF1-up_5176 CXCL12-up_6387|SFRP2-up_6423 CXCL12-up_6387|FZD5-down_7855 EPHA3-up_2042|JUN-down_3725 EPHA3-up_2042|SFRP2-up_6423 EPHA3-up_2042|TCF7L2-up_6934 EPHA3-up_2042|FZD5-down_7855 RND1-down_27289|JUN-down_3725 NTN1-up_9423|JUN-down_3725 RND1-down_27289|MMP7-up_4316 NTN1-up_9423|SERPINF1-up_5176 NTN1-up_9423|SFRP2-up_6423 NTN1-up_9423|SFRP4-up_6424 NTN1-up_9423|SFRP2-up_6423 RND1-down_27289|SFRP4-up_6424 RND1-down_27289
hsa04310	hsa04380	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	0.002	CCND1-up CTSK-up|CCND1-up FHL2-up|CCND1-up FOSL2-down|CCND1-up JAK1-down|CCND1-up SOCS3-down|CCND2-up FOSL2-down|CCND2-up JAK1-down|CCND2-up SOCS3-down|MMP7-up CTSK-up|SERPINF1-up CTSK-up|SFRP2-up FHL2-up|MMP7-up FOSL2-down|TCF7L2-up FOSL2-down|FZD5-down JUN-down|MMP7-up SOCS3-down	CCND1-up_595 CTSK-up_1513|CCND1-up_595 FHL2-up_2274|CCND1-up_595 FOSL2-down_2355|CCND1-up_595 JAK1-down_3716|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 FOSL2-down_2355|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOCS3-down_9021|MMP7-up_4316 CTSK-up_1513|SERPINF1-up_5176 CTSK-up_1513|SFRP2-up_6423 FHL2-up_2274|MMP7-up_4316 FOSL2-down_2355|TCF7L2-up_6934 FOSL2-down_2355|FZD5-down_7855 JUN-down_3725|MMP7-up_4316 SOCS3-down_9021
hsa04310	hsa04390	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.035	CCND1-up JUN-down|CCND2-up JUN-down|JUN-down ID1-down|SERPINF1-up ID1-down|JUN-down SERPINE1-down|JUN-down SOX2-up|JUN-down TCF7L2-up|JUN-down TGFB3-up|MMP7-up SERPINE1-down|MMP7-up TCF7L2-up|SERPINF1-up SERPINE1-down|SFRP2-up SOX2-up|SFRP2-up TCF7L2-up|SFRP2-up TGFB3-up|SFRP4-up TCF7L2-up|SFRP4-up TGFB3-up	CCND1-up_595 JUN-down_3725|CCND2-up_894 JUN-down_3725|JUN-down_3725 ID1-down_3397|SERPINF1-up_5176 ID1-down_3397|JUN-down_3725 SERPINE1-down_5054|JUN-down_3725 SOX2-up_6657|JUN-down_3725 TCF7L2-up_6934|JUN-down_3725 TGFB3-up_7043|MMP7-up_4316 SERPINE1-down_5054|MMP7-up_4316 TCF7L2-up_6934|SERPINF1-up_5176 SERPINE1-down_5054|SFRP2-up_6423 SOX2-up_6657|SFRP2-up_6423 TCF7L2-up_6934|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TCF7L2-up_6934|SFRP4-up_6424 TGFB3-up_7043
hsa04310	hsa04510	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCND1-up FZD5-down|CCND2-up FZD5-down|MMP7-up COL1A1-up|SERPINF1-up COL1A1-up|SFRP2-up COL1A1-up|SFRP4-up COL1A1-up|TCF7L2-up COL1A1-up|MMP7-up COL1A2-up|SERPINF1-up COL1A2-up|SFRP2-up COL1A2-up|SFRP4-up COL1A2-up|MMP7-up COL6A1-up|SERPINF1-up COL6A1-up|MMP7-up COL6A3-up|SERPINF1-up COL6A3-up|MMP7-up COMP-up|MMP7-up FIGF-down|SERPINF1-up FIGF-down|FZD5-down FLT1-down|MMP7-up FLT1-down|SERPINF1-up FLT1-down|SFRP2-up FLT1-down|FZD5-down ITGB8-up|FZD5-down JUN-down|FZD5-down PDGFRA-down|MMP7-up IGF1-up|SERPINF1-up IGF1-up|SFRP2-up IGF1-up|SFRP4-up IGF1-up|TCF7L2-up IGF1-up|MMP7-up LAMA3-down|MMP7-up SPP1-up|MMP7-up THBS1-down|MMP7-up THBS2-up|MMP7-up TNC-up|SFRP2-up PDGFRA-down|SFRP4-up PDGFRA-down|TCF7L2-up PDGFRA-down|SERPINF1-up SPP1-up|SERPINF1-up THBS1-down|SERPINF1-up THBS2-up|SERPINF1-up TNC-up|SFRP2-up SPP1-up|SFRP2-up THBS1-down|SFRP2-up TNC-up|SFRP4-up SPP1-up|SFRP4-up THBS1-down|SFRP4-up THBS2-up	CCND1-up_595 FZD5-down_7855|CCND2-up_894 FZD5-down_7855|MMP7-up_4316 COL1A1-up_1277|SERPINF1-up_5176 COL1A1-up_1277|SFRP2-up_6423 COL1A1-up_1277|SFRP4-up_6424 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|MMP7-up_4316 COL1A2-up_1278|SERPINF1-up_5176 COL1A2-up_1278|SFRP2-up_6423 COL1A2-up_1278|SFRP4-up_6424 COL1A2-up_1278|MMP7-up_4316 COL6A1-up_1291|SERPINF1-up_5176 COL6A1-up_1291|MMP7-up_4316 COL6A3-up_1293|SERPINF1-up_5176 COL6A3-up_1293|MMP7-up_4316 COMP-up_1311|MMP7-up_4316 FIGF-down_2277|SERPINF1-up_5176 FIGF-down_2277|FZD5-down_7855 FLT1-down_2321|MMP7-up_4316 FLT1-down_2321|SERPINF1-up_5176 FLT1-down_2321|SFRP2-up_6423 FLT1-down_2321|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 JUN-down_3725|FZD5-down_7855 PDGFRA-down_5156|MMP7-up_4316 IGF1-up_3479|SERPINF1-up_5176 IGF1-up_3479|SFRP2-up_6423 IGF1-up_3479|SFRP4-up_6424 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|MMP7-up_4316 LAMA3-down_3909|MMP7-up_4316 SPP1-up_6696|MMP7-up_4316 THBS1-down_7057|MMP7-up_4316 THBS2-up_7058|MMP7-up_4316 TNC-up_3371|SFRP2-up_6423 PDGFRA-down_5156|SFRP4-up_6424 PDGFRA-down_5156|TCF7L2-up_6934 PDGFRA-down_5156|SERPINF1-up_5176 SPP1-up_6696|SERPINF1-up_5176 THBS1-down_7057|SERPINF1-up_5176 THBS2-up_7058|SERPINF1-up_5176 TNC-up_3371|SFRP2-up_6423 SPP1-up_6696|SFRP2-up_6423 THBS1-down_7057|SFRP2-up_6423 TNC-up_3371|SFRP4-up_6424 SPP1-up_6696|SFRP4-up_6424 THBS1-down_7057|SFRP4-up_6424 THBS2-up_7058
hsa04310	hsa04512	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up ITGB4-up|CCND1-up LAMA3-down|CCND1-up SPP1-up|CCND1-up THBS1-down|CCND1-up THBS2-up|CCND1-up TNC-up|CCND2-up COL1A2-up|CCND2-up THBS1-down|CCND2-up TNC-up|JUN-down COL1A1-up|MMP7-up COL1A1-up|SERPINF1-up COL1A1-up|SFRP2-up COL1A1-up|SFRP4-up COL1A1-up|TCF7L2-up COL1A1-up|JUN-down COL1A2-up|MMP7-up COL1A2-up|SERPINF1-up COL1A2-up|SFRP2-up COL1A2-up|SFRP4-up COL1A2-up|JUN-down COL6A1-up|MMP7-up COL6A1-up|SERPINF1-up COL6A1-up|JUN-down COL6A3-up|MMP7-up COL6A3-up|SERPINF1-up COL6A3-up|JUN-down COMP-up|MMP7-up COMP-up|FZD5-down ITGB8-up|JUN-down ITGB4-up|JUN-down LAMA3-down|JUN-down SPP1-up|JUN-down THBS1-down|JUN-down THBS2-up|JUN-down TNC-up|MMP7-up LAMA3-down|MMP7-up SPP1-up|MMP7-up THBS1-down|MMP7-up THBS2-up|MMP7-up TNC-up|SERPINF1-up SPP1-up|SERPINF1-up THBS1-down|SERPINF1-up THBS2-up|SERPINF1-up TNC-up|SFRP2-up SPP1-up|SFRP2-up THBS1-down|SFRP2-up TNC-up|SFRP4-up SPP1-up|SFRP4-up THBS1-down|SFRP4-up THBS2-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 SPP1-up_6696|CCND1-up_595 THBS1-down_7057|CCND1-up_595 THBS2-up_7058|CCND1-up_595 TNC-up_3371|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 THBS1-down_7057|CCND2-up_894 TNC-up_3371|JUN-down_3725 COL1A1-up_1277|MMP7-up_4316 COL1A1-up_1277|SERPINF1-up_5176 COL1A1-up_1277|SFRP2-up_6423 COL1A1-up_1277|SFRP4-up_6424 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|MMP7-up_4316 COL1A2-up_1278|SERPINF1-up_5176 COL1A2-up_1278|SFRP2-up_6423 COL1A2-up_1278|SFRP4-up_6424 COL1A2-up_1278|JUN-down_3725 COL6A1-up_1291|MMP7-up_4316 COL6A1-up_1291|SERPINF1-up_5176 COL6A1-up_1291|JUN-down_3725 COL6A3-up_1293|MMP7-up_4316 COL6A3-up_1293|SERPINF1-up_5176 COL6A3-up_1293|JUN-down_3725 COMP-up_1311|MMP7-up_4316 COMP-up_1311|FZD5-down_7855 ITGB8-up_3696|JUN-down_3725 ITGB4-up_3691|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SPP1-up_6696|JUN-down_3725 THBS1-down_7057|JUN-down_3725 THBS2-up_7058|JUN-down_3725 TNC-up_3371|MMP7-up_4316 LAMA3-down_3909|MMP7-up_4316 SPP1-up_6696|MMP7-up_4316 THBS1-down_7057|MMP7-up_4316 THBS2-up_7058|MMP7-up_4316 TNC-up_3371|SERPINF1-up_5176 SPP1-up_6696|SERPINF1-up_5176 THBS1-down_7057|SERPINF1-up_5176 THBS2-up_7058|SERPINF1-up_5176 TNC-up_3371|SFRP2-up_6423 SPP1-up_6696|SFRP2-up_6423 THBS1-down_7057|SFRP2-up_6423 TNC-up_3371|SFRP4-up_6424 SPP1-up_6696|SFRP4-up_6424 THBS1-down_7057|SFRP4-up_6424 THBS2-up_7058
hsa04310	hsa04514	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CCND1-up CD274-down|CCND1-up CDH2-up|CCND1-up CDH3-up|CCND1-up NCAM1-up|CCND1-up VCAM1-up|CCND2-up CDH2-up|CCND2-up NCAM1-up|FZD5-down CDH2-up|JUN-down CDH2-up|MMP7-up CDH2-up|SFRP2-up CDH2-up|SFRP4-up CDH2-up|TCF7L2-up CDH2-up|MMP7-up CDH3-up|MMP7-up CLDN1-up|SFRP4-up CLDN1-up|TCF7L2-up CLDN1-up|JUN-down CLDN5-down|MMP7-up CLDN5-down|SERPINF1-up CLDN5-down|TCF7L2-up CLDN5-down|FZD5-down ITGB8-up|JUN-down NCAM1-up|JUN-down SELL-down|JUN-down VCAM1-up|MMP7-up NCAM1-up|MMP7-up VCAM1-up|SFRP2-up NCAM1-up|SERPINF1-up VCAM1-up	CCND1-up_595 CD274-down_29126|CCND1-up_595 CDH2-up_1000|CCND1-up_595 CDH3-up_1001|CCND1-up_595 NCAM1-up_4684|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CDH2-up_1000|CCND2-up_894 NCAM1-up_4684|FZD5-down_7855 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|MMP7-up_4316 CDH2-up_1000|SFRP2-up_6423 CDH2-up_1000|SFRP4-up_6424 CDH2-up_1000|TCF7L2-up_6934 CDH2-up_1000|MMP7-up_4316 CDH3-up_1001|MMP7-up_4316 CLDN1-up_9076|SFRP4-up_6424 CLDN1-up_9076|TCF7L2-up_6934 CLDN1-up_9076|JUN-down_3725 CLDN5-down_7122|MMP7-up_4316 CLDN5-down_7122|SERPINF1-up_5176 CLDN5-down_7122|TCF7L2-up_6934 CLDN5-down_7122|FZD5-down_7855 ITGB8-up_3696|JUN-down_3725 NCAM1-up_4684|JUN-down_3725 SELL-down_6402|JUN-down_3725 VCAM1-up_7412|MMP7-up_4316 NCAM1-up_4684|MMP7-up_4316 VCAM1-up_7412|SFRP2-up_6423 NCAM1-up_4684|SERPINF1-up_5176 VCAM1-up_7412
hsa04310	hsa04550	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.006	CCND1-up ID1-down|CCND1-up IGF1-up|CCND1-up JAK1-down|CCND1-up LIFR-down|CCND1-up SOX2-up|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up SOX2-up|JUN-down ID1-down|SERPINF1-up ID1-down|JUN-down IGF1-up|MMP7-up IGF1-up|SERPINF1-up IGF1-up|SFRP2-up IGF1-up|SFRP4-up IGF1-up|TCF7L2-up IGF1-up|JUN-down JAK1-down|JUN-down LIFR-down|JUN-down SOX2-up|SFRP2-up SOX2-up	CCND1-up_595 ID1-down_3397|CCND1-up_595 IGF1-up_3479|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LIFR-down_3977|CCND1-up_595 SOX2-up_6657|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOX2-up_6657|JUN-down_3725 ID1-down_3397|SERPINF1-up_5176 ID1-down_3397|JUN-down_3725 IGF1-up_3479|MMP7-up_4316 IGF1-up_3479|SERPINF1-up_5176 IGF1-up_3479|SFRP2-up_6423 IGF1-up_3479|SFRP4-up_6424 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|JUN-down_3725 JAK1-down_3716|JUN-down_3725 LIFR-down_3977|JUN-down_3725 SOX2-up_6657|SFRP2-up_6423 SOX2-up_6657
hsa04310	hsa04610	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0	CCND1-up CFH-up|CCND1-up PLAU-up|CCND1-up SERPINE1-down|CCND2-up PLAU-up|CCND2-up SERPINE1-down|JUN-down CFH-up|SERPINF1-up CFH-up|JUN-down F3-down|MMP7-up F3-down|JUN-down PLAU-up|JUN-down SERPINE1-down|JUN-down TFPI-down|SERPINF1-up MASP1-up|TCF7L2-up MASP1-up|MMP7-up PLAU-up|MMP7-up SERPINE1-down|MMP7-up TFPI-down|SERPINF1-up PLAU-up|SERPINF1-up SERPIND1-up|SERPINF1-up SERPINE1-down	CCND1-up_595 CFH-up_3075|CCND1-up_595 PLAU-up_5328|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 PLAU-up_5328|CCND2-up_894 SERPINE1-down_5054|JUN-down_3725 CFH-up_3075|SERPINF1-up_5176 CFH-up_3075|JUN-down_3725 F3-down_2152|MMP7-up_4316 F3-down_2152|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINE1-down_5054|JUN-down_3725 TFPI-down_7035|SERPINF1-up_5176 MASP1-up_5648|TCF7L2-up_6934 MASP1-up_5648|MMP7-up_4316 PLAU-up_5328|MMP7-up_4316 SERPINE1-down_5054|MMP7-up_4316 TFPI-down_7035|SERPINF1-up_5176 PLAU-up_5328|SERPINF1-up_5176 SERPIND1-up_3053|SERPINF1-up_5176 SERPINE1-down_5054
hsa04310	hsa04668	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.007	CCND1-up MAP3K8-down|CCND1-up SOCS3-down|CCND1-up VCAM1-up|CCND2-up CXCL2-down|CCND2-up MAP3K8-down|CCND2-up SOCS3-down|MMP7-up CXCL2-down|MMP7-up CXCL3-down|FZD5-down JUN-down|FZD5-down MAP3K8-down|MMP7-up SOCS3-down|MMP7-up VCAM1-up|SERPINF1-up VCAM1-up	CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 SOCS3-down_9021|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL2-down_2920|CCND2-up_894 MAP3K8-down_1326|CCND2-up_894 SOCS3-down_9021|MMP7-up_4316 CXCL2-down_2920|MMP7-up_4316 CXCL3-down_2921|FZD5-down_7855 JUN-down_3725|FZD5-down_7855 MAP3K8-down_1326|MMP7-up_4316 SOCS3-down_9021|MMP7-up_4316 VCAM1-up_7412|SERPINF1-up_5176 VCAM1-up_7412
hsa04310	hsa04670	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|CCND2-up CXCL12-up|CCND2-up MMP2-up|MMP7-up CLDN1-up|SFRP4-up CLDN1-up|TCF7L2-up CLDN1-up|JUN-down CLDN5-down|MMP7-up CLDN5-down|SERPINF1-up CLDN5-down|TCF7L2-up CLDN5-down|JUN-down CXCL12-up|MMP7-up CXCL12-up|SERPINF1-up CXCL12-up|SFRP2-up CXCL12-up|JUN-down MMP2-up|JUN-down THY1-up|JUN-down VCAM1-up|MMP7-up MMP2-up|SERPINF1-up MMP2-up|SFRP2-up MMP2-up|SFRP4-up MMP2-up|TCF7L2-up MMP2-up|MMP7-up VCAM1-up|SERPINF1-up VCAM1-up	CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP2-up_4313|MMP7-up_4316 CLDN1-up_9076|SFRP4-up_6424 CLDN1-up_9076|TCF7L2-up_6934 CLDN1-up_9076|JUN-down_3725 CLDN5-down_7122|MMP7-up_4316 CLDN5-down_7122|SERPINF1-up_5176 CLDN5-down_7122|TCF7L2-up_6934 CLDN5-down_7122|JUN-down_3725 CXCL12-up_6387|MMP7-up_4316 CXCL12-up_6387|SERPINF1-up_5176 CXCL12-up_6387|SFRP2-up_6423 CXCL12-up_6387|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THY1-up_7070|JUN-down_3725 VCAM1-up_7412|MMP7-up_4316 MMP2-up_4313|SERPINF1-up_5176 MMP2-up_4313|SFRP2-up_6423 MMP2-up_4313|SFRP4-up_6424 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|MMP7-up_4316 VCAM1-up_7412|SERPINF1-up_5176 VCAM1-up_7412
hsa04310	hsa04915	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.007	CCND1-up HBEGF-down|CCND1-up HSPA1A-down|CCND1-up MMP2-up|CCND2-up HBEGF-down|CCND2-up MMP2-up|FZD5-down GABBR2-up|FZD5-down JUN-down|MMP7-up HBEGF-down|SERPINF1-up HBEGF-down|SFRP2-up HBEGF-down|MMP7-up MMP2-up|SERPINF1-up MMP2-up|SFRP2-up MMP2-up|SFRP4-up MMP2-up|TCF7L2-up MMP2-up	CCND1-up_595 HBEGF-down_1839|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 MMP2-up_4313|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP2-up_4313|FZD5-down_7855 GABBR2-up_9568|FZD5-down_7855 JUN-down_3725|MMP7-up_4316 HBEGF-down_1839|SERPINF1-up_5176 HBEGF-down_1839|SFRP2-up_6423 HBEGF-down_1839|MMP7-up_4316 MMP2-up_4313|SERPINF1-up_5176 MMP2-up_4313|SFRP2-up_6423 MMP2-up_4313|SFRP4-up_6424 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313
hsa04310	hsa04933	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CCND1-up FZD5-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up MMP2-up|CCND2-up SERPINE1-down|CCND2-up TGFB3-up|MMP7-up COL1A1-up|SERPINF1-up COL1A1-up|SFRP2-up COL1A1-up|SFRP4-up COL1A1-up|TCF7L2-up COL1A1-up|MMP7-up COL1A2-up|SERPINF1-up COL1A2-up|SFRP2-up COL1A2-up|SFRP4-up COL1A2-up|MMP7-up COL3A1-up|SERPINF1-up COL3A1-up|SFRP2-up COL3A1-up|MMP7-up F3-down|MMP7-up FIGF-down|SERPINF1-up FIGF-down|FZD5-down JUN-down|MMP7-up MMP2-up|SERPINF1-up MMP2-up|SFRP2-up MMP2-up|SFRP4-up MMP2-up|TCF7L2-up MMP2-up|MMP7-up SERPINE1-down|MMP7-up VCAM1-up|SERPINF1-up SERPINE1-down|SERPINF1-up VCAM1-up|SFRP2-up TGFB3-up|SFRP4-up TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 FZD5-down_7855|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 MMP2-up_4313|CCND2-up_894 SERPINE1-down_5054|CCND2-up_894 TGFB3-up_7043|MMP7-up_4316 COL1A1-up_1277|SERPINF1-up_5176 COL1A1-up_1277|SFRP2-up_6423 COL1A1-up_1277|SFRP4-up_6424 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|MMP7-up_4316 COL1A2-up_1278|SERPINF1-up_5176 COL1A2-up_1278|SFRP2-up_6423 COL1A2-up_1278|SFRP4-up_6424 COL1A2-up_1278|MMP7-up_4316 COL3A1-up_1281|SERPINF1-up_5176 COL3A1-up_1281|SFRP2-up_6423 COL3A1-up_1281|MMP7-up_4316 F3-down_2152|MMP7-up_4316 FIGF-down_2277|SERPINF1-up_5176 FIGF-down_2277|FZD5-down_7855 JUN-down_3725|MMP7-up_4316 MMP2-up_4313|SERPINF1-up_5176 MMP2-up_4313|SFRP2-up_6423 MMP2-up_4313|SFRP4-up_6424 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|MMP7-up_4316 SERPINE1-down_5054|MMP7-up_4316 VCAM1-up_7412|SERPINF1-up_5176 SERPINE1-down_5054|SERPINF1-up_5176 VCAM1-up_7412|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04310	hsa04974	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CCND1-up COL18A1-up|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up MME-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up MME-down|JUN-down COL14A1-up|MMP7-up COL14A1-up|MMP7-up COL17A1-up|JUN-down COL18A1-up|MMP7-up COL18A1-up|SERPINF1-up COL18A1-up|JUN-down COL1A1-up|MMP7-up COL1A1-up|SERPINF1-up COL1A1-up|SFRP2-up COL1A1-up|SFRP4-up COL1A1-up|TCF7L2-up COL1A1-up|JUN-down COL1A2-up|MMP7-up COL1A2-up|SERPINF1-up COL1A2-up|SFRP2-up COL1A2-up|SFRP4-up COL1A2-up|JUN-down COL3A1-up|MMP7-up COL3A1-up|SERPINF1-up COL3A1-up|SFRP2-up COL3A1-up|JUN-down COL5A1-up|MMP7-up COL5A1-up|SFRP4-up COL5A1-up|JUN-down COL5A2-up|MMP7-up COL5A2-up|JUN-down COL6A1-up|MMP7-up COL6A1-up|SERPINF1-up COL6A1-up|JUN-down COL6A3-up|MMP7-up COL6A3-up|SERPINF1-up COL6A3-up|JUN-down COL7A1-up|MMP7-up COL7A1-up|JUN-down KCNN4-up|JUN-down MME-down|JUN-down PRSS1-up|MMP7-up MME-down|SFRP4-up MME-down|MMP7-up PRSS1-up	CCND1-up_595 COL18A1-up_80781|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 MME-down_4311|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 MME-down_4311|JUN-down_3725 COL14A1-up_7373|MMP7-up_4316 COL14A1-up_7373|MMP7-up_4316 COL17A1-up_1308|JUN-down_3725 COL18A1-up_80781|MMP7-up_4316 COL18A1-up_80781|SERPINF1-up_5176 COL18A1-up_80781|JUN-down_3725 COL1A1-up_1277|MMP7-up_4316 COL1A1-up_1277|SERPINF1-up_5176 COL1A1-up_1277|SFRP2-up_6423 COL1A1-up_1277|SFRP4-up_6424 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|MMP7-up_4316 COL1A2-up_1278|SERPINF1-up_5176 COL1A2-up_1278|SFRP2-up_6423 COL1A2-up_1278|SFRP4-up_6424 COL1A2-up_1278|JUN-down_3725 COL3A1-up_1281|MMP7-up_4316 COL3A1-up_1281|SERPINF1-up_5176 COL3A1-up_1281|SFRP2-up_6423 COL3A1-up_1281|JUN-down_3725 COL5A1-up_1289|MMP7-up_4316 COL5A1-up_1289|SFRP4-up_6424 COL5A1-up_1289|JUN-down_3725 COL5A2-up_1290|MMP7-up_4316 COL5A2-up_1290|JUN-down_3725 COL6A1-up_1291|MMP7-up_4316 COL6A1-up_1291|SERPINF1-up_5176 COL6A1-up_1291|JUN-down_3725 COL6A3-up_1293|MMP7-up_4316 COL6A3-up_1293|SERPINF1-up_5176 COL6A3-up_1293|JUN-down_3725 COL7A1-up_1294|MMP7-up_4316 COL7A1-up_1294|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MME-down_4311|JUN-down_3725 PRSS1-up_5644|MMP7-up_4316 MME-down_4311|SFRP4-up_6424 MME-down_4311|MMP7-up_4316 PRSS1-up_5644
hsa04310	hsa04978	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.004	CCND1-up HMOX1-down|CCND1-up TF-up|CCND2-up HMOX1-down|CCND2-up TF-up|JUN-down HMOX1-down|MMP7-up HMOX1-down|SERPINF1-up HMOX1-down|JUN-down MT1E-down|JUN-down MT1X-down|JUN-down MT2A-down|JUN-down TF-up|MMP7-up TF-up|SFRP4-up MT1G-down|SERPINF1-up TF-up	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|CCND2-up_894 HMOX1-down_3162|CCND2-up_894 TF-up_7018|JUN-down_3725 HMOX1-down_3162|MMP7-up_4316 HMOX1-down_3162|SERPINF1-up_5176 HMOX1-down_3162|JUN-down_3725 MT1E-down_4493|JUN-down_3725 MT1X-down_4501|JUN-down_3725 MT2A-down_4502|JUN-down_3725 TF-up_7018|MMP7-up_4316 TF-up_7018|SFRP4-up_6424 MT1G-down_4495|SERPINF1-up_5176 TF-up_7018
hsa04310	hsa05146	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up LAMA3-down|CCND1-up TGFB3-up|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up TGFB3-up|JUN-down COL1A1-up|MMP7-up COL1A1-up|SERPINF1-up COL1A1-up|SFRP2-up COL1A1-up|SFRP4-up COL1A1-up|TCF7L2-up COL1A1-up|JUN-down COL1A2-up|MMP7-up COL1A2-up|SERPINF1-up COL1A2-up|SFRP2-up COL1A2-up|SFRP4-up COL1A2-up|JUN-down COL3A1-up|MMP7-up COL3A1-up|SERPINF1-up COL3A1-up|SFRP2-up COL3A1-up|JUN-down LAMA3-down|JUN-down SERPINB3-up|JUN-down TGFB3-up|MMP7-up LAMA3-down|SERPINF1-up SERPINB3-up|SFRP2-up TGFB3-up|SFRP4-up TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 TGFB3-up_7043|JUN-down_3725 COL1A1-up_1277|MMP7-up_4316 COL1A1-up_1277|SERPINF1-up_5176 COL1A1-up_1277|SFRP2-up_6423 COL1A1-up_1277|SFRP4-up_6424 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|MMP7-up_4316 COL1A2-up_1278|SERPINF1-up_5176 COL1A2-up_1278|SFRP2-up_6423 COL1A2-up_1278|SFRP4-up_6424 COL1A2-up_1278|JUN-down_3725 COL3A1-up_1281|MMP7-up_4316 COL3A1-up_1281|SERPINF1-up_5176 COL3A1-up_1281|SFRP2-up_6423 COL3A1-up_1281|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SERPINB3-up_6317|JUN-down_3725 TGFB3-up_7043|MMP7-up_4316 LAMA3-down_3909|SERPINF1-up_5176 SERPINB3-up_6317|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04310	hsa05152	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.029	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|JUN-down CD74-up|JUN-down JAK1-down|JUN-down TGFB3-up|SFRP2-up TGFB3-up|SFRP4-up TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|JUN-down_3725 CD74-up_972|JUN-down_3725 JAK1-down_3716|JUN-down_3725 TGFB3-up_7043|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04310	hsa05160	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0.001	CCND1-up JAK1-down|CCND1-up LDLR-down|CCND1-up SOCS3-down|CCND2-up JAK1-down|CCND2-up SOCS3-down|MMP7-up CLDN1-up|SFRP4-up CLDN1-up|TCF7L2-up CLDN1-up|JUN-down CLDN5-down|MMP7-up CLDN5-down|SERPINF1-up CLDN5-down|TCF7L2-up CLDN5-down|JUN-down JAK1-down|JUN-down LDLR-down|JUN-down SOCS3-down|TCF7L2-up LDLR-down|MMP7-up SOCS3-down	CCND1-up_595 JAK1-down_3716|CCND1-up_595 LDLR-down_3949|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOCS3-down_9021|MMP7-up_4316 CLDN1-up_9076|SFRP4-up_6424 CLDN1-up_9076|TCF7L2-up_6934 CLDN1-up_9076|JUN-down_3725 CLDN5-down_7122|MMP7-up_4316 CLDN5-down_7122|SERPINF1-up_5176 CLDN5-down_7122|TCF7L2-up_6934 CLDN5-down_7122|JUN-down_3725 JAK1-down_3716|JUN-down_3725 LDLR-down_3949|JUN-down_3725 SOCS3-down_9021|TCF7L2-up_6934 LDLR-down_3949|MMP7-up_4316 SOCS3-down_9021
hsa04310	hsa05200	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	CCND2-up CXCL12-up|CCND2-up HHIP-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up PDGFRA-down|CCND2-up TCF7L2-up|CCND2-up TGFB3-up|CCND2-up ZBTB16-down|MMP7-up CXCL12-up|SERPINF1-up CXCL12-up|SFRP2-up CXCL12-up|MMP7-up EDNRB-down|SERPINF1-up EDNRB-down|SFRP4-up FGF14-up|MMP7-up FIGF-down|SERPINF1-up FIGF-down|SFRP2-up HHIP-down|MMP7-up IGF1-up|SERPINF1-up IGF1-up|SFRP2-up IGF1-up|SFRP4-up IGF1-up|MMP7-up LAMA3-down|MMP7-up MMP1-up|SERPINF1-up MMP1-up|SFRP2-up MMP1-up|SFRP4-up MMP1-up|MMP7-up MMP2-up|SERPINF1-up MMP2-up|SFRP2-up MMP2-up|SFRP4-up MMP2-up|MMP7-up TCF7L2-up|SFRP2-up PDGFRA-down|SFRP4-up PDGFRA-down|SFRP2-up TCF7L2-up|SFRP2-up TGFB3-up|SFRP4-up TCF7L2-up|SFRP4-up TGFB3-up	CCND2-up_894 CXCL12-up_6387|CCND2-up_894 HHIP-down_64399|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 TCF7L2-up_6934|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 ZBTB16-down_7704|MMP7-up_4316 CXCL12-up_6387|SERPINF1-up_5176 CXCL12-up_6387|SFRP2-up_6423 CXCL12-up_6387|MMP7-up_4316 EDNRB-down_1910|SERPINF1-up_5176 EDNRB-down_1910|SFRP4-up_6424 FGF14-up_2259|MMP7-up_4316 FIGF-down_2277|SERPINF1-up_5176 FIGF-down_2277|SFRP2-up_6423 HHIP-down_64399|MMP7-up_4316 IGF1-up_3479|SERPINF1-up_5176 IGF1-up_3479|SFRP2-up_6423 IGF1-up_3479|SFRP4-up_6424 IGF1-up_3479|MMP7-up_4316 LAMA3-down_3909|MMP7-up_4316 MMP1-up_4312|SERPINF1-up_5176 MMP1-up_4312|SFRP2-up_6423 MMP1-up_4312|SFRP4-up_6424 MMP1-up_4312|MMP7-up_4316 MMP2-up_4313|SERPINF1-up_5176 MMP2-up_4313|SFRP2-up_6423 MMP2-up_4313|SFRP4-up_6424 MMP2-up_4313|MMP7-up_4316 TCF7L2-up_6934|SFRP2-up_6423 PDGFRA-down_5156|SFRP4-up_6424 PDGFRA-down_5156|SFRP2-up_6423 TCF7L2-up_6934|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TCF7L2-up_6934|SFRP4-up_6424 TGFB3-up_7043
hsa04310	hsa05202	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up FZD5-down|CCND2-up JUN-down|MMP7-up DEFA3-down|FZD5-down FLT1-down|JUN-down FLT1-down|MMP7-up FLT1-down|SERPINF1-up FLT1-down|SFRP2-up FLT1-down|FZD5-down PROM1-up|JUN-down IGF1-up|MMP7-up IGF1-up|SERPINF1-up IGF1-up|SFRP2-up IGF1-up|SFRP4-up IGF1-up|TCF7L2-up IGF1-up|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|MMP7-up PLAU-up|MMP7-up PROM1-up|SERPINF1-up PLAU-up|SERPINF1-up PROM1-up|SFRP2-up PROM1-up	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 FZD5-down_7855|CCND2-up_894 JUN-down_3725|MMP7-up_4316 DEFA3-down_1668|FZD5-down_7855 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|MMP7-up_4316 FLT1-down_2321|SERPINF1-up_5176 FLT1-down_2321|SFRP2-up_6423 FLT1-down_2321|FZD5-down_7855 PROM1-up_8842|JUN-down_3725 IGF1-up_3479|MMP7-up_4316 IGF1-up_3479|SERPINF1-up_5176 IGF1-up_3479|SFRP2-up_6423 IGF1-up_3479|SFRP4-up_6424 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|MMP7-up_4316 PLAU-up_5328|MMP7-up_4316 PROM1-up_8842|SERPINF1-up_5176 PLAU-up_5328|SERPINF1-up_5176 PROM1-up_8842|SFRP2-up_6423 PROM1-up_8842
hsa04310	hsa05205	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	TCF7L2-up ANK2-up|JUN-down CAV2-down|CCND1-up JUN-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|CCND2-up THBS1-down|JUN-down FLNC-up|JUN-down HBEGF-down|MMP7-up HBEGF-down|SERPINF1-up HBEGF-down|SFRP2-up HBEGF-down|JUN-down IGF1-up|MMP7-up IGF1-up|SERPINF1-up IGF1-up|SFRP2-up IGF1-up|SFRP4-up IGF1-up|TCF7L2-up IGF1-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|MMP7-up MMP2-up|SERPINF1-up MMP2-up|SFRP2-up MMP2-up|SFRP4-up MMP2-up|TCF7L2-up MMP2-up|MMP7-up PLAU-up|MMP7-up THBS1-down|SERPINF1-up PLAU-up|SERPINF1-up THBS1-down|SFRP2-up THBS1-down|SFRP4-up THBS1-down	TCF7L2-up_6934 ANK2-up_287|JUN-down_3725 CAV2-down_858|CCND1-up_595 JUN-down_3725|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|CCND2-up_894 THBS1-down_7057|JUN-down_3725 FLNC-up_2318|JUN-down_3725 HBEGF-down_1839|MMP7-up_4316 HBEGF-down_1839|SERPINF1-up_5176 HBEGF-down_1839|SFRP2-up_6423 HBEGF-down_1839|JUN-down_3725 IGF1-up_3479|MMP7-up_4316 IGF1-up_3479|SERPINF1-up_5176 IGF1-up_3479|SFRP2-up_6423 IGF1-up_3479|SFRP4-up_6424 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|MMP7-up_4316 MMP2-up_4313|SERPINF1-up_5176 MMP2-up_4313|SFRP2-up_6423 MMP2-up_4313|SFRP4-up_6424 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|MMP7-up_4316 PLAU-up_5328|MMP7-up_4316 THBS1-down_7057|SERPINF1-up_5176 PLAU-up_5328|SERPINF1-up_5176 THBS1-down_7057|SFRP2-up_6423 THBS1-down_7057|SFRP4-up_6424 THBS1-down_7057
hsa04310	hsa05206	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.002	CCND1-up FZD5-down|CCND1-up JUN-down|CCND2-up FZD5-down|CCND2-up JUN-down|JUN-down CYP24A1-up|FZD5-down PDGFRA-down|JUN-down HMOX1-down|MMP7-up HMOX1-down|SERPINF1-up HMOX1-down|JUN-down IRS2-down|TCF7L2-up IRS2-down|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|MMP7-up PLAU-up|MMP7-up SERPINB5-up|MMP7-up THBS1-down|MMP7-up TNC-up|SFRP2-up PDGFRA-down|SFRP4-up PDGFRA-down|TCF7L2-up PDGFRA-down|SERPINF1-up PLAU-up|SERPINF1-up SERPINB5-up|SERPINF1-up THBS1-down|SERPINF1-up TNC-up|SERPINF1-up TP63-up|SFRP2-up THBS1-down|SFRP2-up TNC-up|SFRP4-up SOX4-up|SFRP4-up THBS1-down|TCF7L2-up TP63-up	CCND1-up_595 FZD5-down_7855|CCND1-up_595 JUN-down_3725|CCND2-up_894 FZD5-down_7855|CCND2-up_894 JUN-down_3725|JUN-down_3725 CYP24A1-up_1591|FZD5-down_7855 PDGFRA-down_5156|JUN-down_3725 HMOX1-down_3162|MMP7-up_4316 HMOX1-down_3162|SERPINF1-up_5176 HMOX1-down_3162|JUN-down_3725 IRS2-down_8660|TCF7L2-up_6934 IRS2-down_8660|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|MMP7-up_4316 PLAU-up_5328|MMP7-up_4316 SERPINB5-up_5268|MMP7-up_4316 THBS1-down_7057|MMP7-up_4316 TNC-up_3371|SFRP2-up_6423 PDGFRA-down_5156|SFRP4-up_6424 PDGFRA-down_5156|TCF7L2-up_6934 PDGFRA-down_5156|SERPINF1-up_5176 PLAU-up_5328|SERPINF1-up_5176 SERPINB5-up_5268|SERPINF1-up_5176 THBS1-down_7057|SERPINF1-up_5176 TNC-up_3371|SERPINF1-up_5176 TP63-up_8626|SFRP2-up_6423 THBS1-down_7057|SFRP2-up_6423 TNC-up_3371|SFRP4-up_6424 SOX4-up_6659|SFRP4-up_6424 THBS1-down_7057|TCF7L2-up_6934 TP63-up_8626
hsa04310	hsa05219	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCND1-up FZD5-down|CCND1-up JUN-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up THBS1-down|JUN-down HBEGF-down|MMP7-up HBEGF-down|SERPINF1-up HBEGF-down|SFRP2-up HBEGF-down|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|MMP7-up MMP1-up|SERPINF1-up MMP1-up|SFRP2-up MMP1-up|SFRP4-up MMP1-up|MMP7-up MMP2-up|SERPINF1-up MMP2-up|SFRP2-up MMP2-up|SFRP4-up MMP2-up|TCF7L2-up MMP2-up|MMP7-up THBS1-down|SERPINF1-up THBS1-down|SFRP2-up THBS1-down|SFRP4-up THBS1-down	CCND1-up_595 FZD5-down_7855|CCND1-up_595 JUN-down_3725|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 THBS1-down_7057|JUN-down_3725 HBEGF-down_1839|MMP7-up_4316 HBEGF-down_1839|SERPINF1-up_5176 HBEGF-down_1839|SFRP2-up_6423 HBEGF-down_1839|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|MMP7-up_4316 MMP1-up_4312|SERPINF1-up_5176 MMP1-up_4312|SFRP2-up_6423 MMP1-up_4312|SFRP4-up_6424 MMP1-up_4312|MMP7-up_4316 MMP2-up_4313|SERPINF1-up_5176 MMP2-up_4313|SFRP2-up_6423 MMP2-up_4313|SFRP4-up_6424 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|MMP7-up_4316 THBS1-down_7057|SERPINF1-up_5176 THBS1-down_7057|SFRP2-up_6423 THBS1-down_7057|SFRP4-up_6424 THBS1-down_7057
hsa04310	hsa05323	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up FLT1-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|MMP7-up CTSK-up|SERPINF1-up CTSK-up|MMP7-up CXCL12-up|SERPINF1-up CXCL12-up|SFRP2-up CXCL12-up|FZD5-down FLT1-down|MMP7-up FLT1-down|SERPINF1-up FLT1-down|SFRP2-up FLT1-down|FZD5-down JUN-down|MMP7-up MMP1-up|SERPINF1-up MMP1-up|SFRP2-up MMP1-up|SFRP4-up MMP1-up|SFRP2-up TGFB3-up|SFRP4-up TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FLT1-down_2321|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|MMP7-up_4316 CTSK-up_1513|SERPINF1-up_5176 CTSK-up_1513|MMP7-up_4316 CXCL12-up_6387|SERPINF1-up_5176 CXCL12-up_6387|SFRP2-up_6423 CXCL12-up_6387|FZD5-down_7855 FLT1-down_2321|MMP7-up_4316 FLT1-down_2321|SERPINF1-up_5176 FLT1-down_2321|SFRP2-up_6423 FLT1-down_2321|FZD5-down_7855 JUN-down_3725|MMP7-up_4316 MMP1-up_4312|SERPINF1-up_5176 MMP1-up_4312|SFRP2-up_6423 MMP1-up_4312|SFRP4-up_6424 MMP1-up_4312|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04310	hsa05410	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.003	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|FZD5-down ITGB8-up|JUN-down IGF1-up|MMP7-up IGF1-up|SERPINF1-up IGF1-up|SFRP2-up IGF1-up|SFRP4-up IGF1-up|TCF7L2-up IGF1-up|JUN-down ITGB4-up|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|SFRP2-up TGFB3-up|SFRP4-up TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|FZD5-down_7855 ITGB8-up_3696|JUN-down_3725 IGF1-up_3479|MMP7-up_4316 IGF1-up_3479|SERPINF1-up_5176 IGF1-up_3479|SFRP2-up_6423 IGF1-up_3479|SFRP4-up_6424 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04310	hsa05412	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.001	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|FZD5-down CDH2-up|JUN-down CDH2-up|MMP7-up CDH2-up|SFRP2-up CDH2-up|SFRP4-up CDH2-up|FZD5-down ITGB8-up|FZD5-down TCF7L2-up|JUN-down ITGB4-up|JUN-down TCF7L2-up|MMP7-up TCF7L2-up|SFRP2-up TCF7L2-up|SFRP4-up TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|FZD5-down_7855 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|MMP7-up_4316 CDH2-up_1000|SFRP2-up_6423 CDH2-up_1000|SFRP4-up_6424 CDH2-up_1000|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 TCF7L2-up_6934|JUN-down_3725 ITGB4-up_3691|JUN-down_3725 TCF7L2-up_6934|MMP7-up_4316 TCF7L2-up_6934|SFRP2-up_6423 TCF7L2-up_6934|SFRP4-up_6424 TCF7L2-up_6934
hsa04310	hsa05414	Wnt signaling pathway - Homo sapiens (human)	FZD5,JUN,CCND1,CCND2,MMP7,SERPINF1,SFRP2,SFRP4,TCF7L2	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.023	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up TGFB3-up|FZD5-down ITGB8-up|JUN-down IGF1-up|MMP7-up IGF1-up|SERPINF1-up IGF1-up|SFRP2-up IGF1-up|SFRP4-up IGF1-up|TCF7L2-up IGF1-up|JUN-down ITGB4-up|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down|SFRP2-up TGFB3-up|SFRP4-up TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 TGFB3-up_7043|FZD5-down_7855 ITGB8-up_3696|JUN-down_3725 IGF1-up_3479|MMP7-up_4316 IGF1-up_3479|SERPINF1-up_5176 IGF1-up_3479|SFRP2-up_6423 IGF1-up_3479|SFRP4-up_6424 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|SFRP2-up_6423 TGFB3-up_7043|SFRP4-up_6424 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04350	hsa04390	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.005	SMAD6-down CCND1-up|THBS1-down CCND1-up|SMAD6-down CCND2-up|THBS1-down CCND2-up|LTBP1-up SERPINE1-down|LTBP1-up TGFB3-up|SMAD6-down SERPINE1-down|THBS1-down SERPINE1-down|SMAD6-down SOX2-up|SMAD6-down TCF7L2-up|SMAD6-down TGFB3-up|THBS1-down SOX2-up|TGFB3-up THBS1-down	SMAD6-down_4091 CCND1-up_595|THBS1-down_7057 CCND1-up_595|SMAD6-down_4091 CCND2-up_894|THBS1-down_7057 CCND2-up_894|LTBP1-up_4052 SERPINE1-down_5054|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|SMAD6-down_4091 SOX2-up_6657|SMAD6-down_4091 TCF7L2-up_6934|SMAD6-down_4091 TGFB3-up_7043|THBS1-down_7057 SOX2-up_6657|TGFB3-up_7043 THBS1-down_7057
hsa04350	hsa04510	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0	ID1-down CCND1-up|SMAD6-down CCND1-up|TGFB3-up CCND1-up|SMAD6-down CCND2-up|TGFB3-up CCND2-up|LTBP1-up COL1A1-up|SMAD6-down COL1A1-up|TGFB3-up COL1A1-up|LTBP1-up COL1A2-up|SMAD6-down COL1A2-up|TGFB3-up COL1A2-up|LTBP1-up COL6A1-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|TGFB3-up COMP-up|TGFB3-up FIGF-down|ID1-down FLT1-down|SMAD6-down FLT1-down|TGFB3-up FLT1-down|ID1-down IGF1-up|ID1-down JUN-down|ID1-down PDGFRA-down|ID1-down SPP1-up|ID1-down THBS1-down|ID1-down THBS2-up|SMAD6-down IGF1-up|TGFB3-up IGF1-up|TGFB3-up ITGB8-up|SMAD6-down JUN-down|TGFB3-up JUN-down|LTBP1-up LAMA3-down|LTBP1-up PDGFRA-down|LTBP1-up THBS2-up|TGFB3-up PDGFRA-down|SMAD6-down SPP1-up|SMAD6-down THBS1-down|SMAD6-down TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS2-up|TGFB3-up TNC-up	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|SMAD6-down_4091 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|LTBP1-up_4052 COL1A1-up_1277|SMAD6-down_4091 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|LTBP1-up_4052 COL1A2-up_1278|SMAD6-down_4091 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|LTBP1-up_4052 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|TGFB3-up_7043 COMP-up_1311|TGFB3-up_7043 FIGF-down_2277|ID1-down_3397 FLT1-down_2321|SMAD6-down_4091 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|ID1-down_3397 IGF1-up_3479|ID1-down_3397 JUN-down_3725|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 SPP1-up_6696|ID1-down_3397 THBS1-down_7057|ID1-down_3397 THBS2-up_7058|SMAD6-down_4091 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TGFB3-up_7043 ITGB8-up_3696|SMAD6-down_4091 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|LTBP1-up_4052 LAMA3-down_3909|LTBP1-up_4052 PDGFRA-down_5156|LTBP1-up_4052 THBS2-up_7058|TGFB3-up_7043 PDGFRA-down_5156|SMAD6-down_4091 SPP1-up_6696|SMAD6-down_4091 THBS1-down_7057|SMAD6-down_4091 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04350	hsa04512	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	LTBP1-up COL1A1-up|SMAD6-down COL1A1-up|TGFB3-up COL1A1-up|LTBP1-up COL1A2-up|SMAD6-down COL1A2-up|TGFB3-up COL1A2-up|LTBP1-up COL6A1-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|TGFB3-up COMP-up|ID1-down SPP1-up|ID1-down THBS1-down|ID1-down THBS2-up|TGFB3-up ITGB8-up|LTBP1-up LAMA3-down|LTBP1-up THBS2-up|SMAD6-down SPP1-up|SMAD6-down THBS1-down|SMAD6-down TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS2-up|TGFB3-up TNC-up	LTBP1-up_4052 COL1A1-up_1277|SMAD6-down_4091 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|LTBP1-up_4052 COL1A2-up_1278|SMAD6-down_4091 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|LTBP1-up_4052 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|TGFB3-up_7043 COMP-up_1311|ID1-down_3397 SPP1-up_6696|ID1-down_3397 THBS1-down_7057|ID1-down_3397 THBS2-up_7058|TGFB3-up_7043 ITGB8-up_3696|LTBP1-up_4052 LAMA3-down_3909|LTBP1-up_4052 THBS2-up_7058|SMAD6-down_4091 SPP1-up_6696|SMAD6-down_4091 THBS1-down_7057|SMAD6-down_4091 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04350	hsa04514	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0.002	SMAD6-down CDH2-up|TGFB3-up CDH2-up|THBS1-down CDH2-up|THBS1-down CLDN1-up|THBS1-down CLDN5-down|TGFB3-up ITGB8-up|THBS1-down ITGB8-up|TGFB3-up NCAM1-up|THBS1-down NCAM1-up|TGFB3-up VCAM1-up|THBS1-down VCAM1-up	SMAD6-down_4091 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS1-down_7057 CLDN1-up_9076|THBS1-down_7057 CLDN5-down_7122|TGFB3-up_7043 ITGB8-up_3696|THBS1-down_7057 ITGB8-up_3696|TGFB3-up_7043 NCAM1-up_4684|THBS1-down_7057 NCAM1-up_4684|TGFB3-up_7043 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412
hsa04350	hsa04610	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.001	THBS1-down CFH-up|THBS1-down F3-down|ID1-down PLAU-up|ID1-down SERPINE1-down|LTBP1-up SERPINE1-down|TGFB3-up PLAU-up|THBS1-down PLAU-up|SMAD6-down SERPINE1-down|TGFB3-up SERPINE1-down|THBS1-down SERPINE1-down|THBS1-down TFPI-down	THBS1-down_7057 CFH-up_3075|THBS1-down_7057 F3-down_2152|ID1-down_3397 PLAU-up_5328|ID1-down_3397 SERPINE1-down_5054|LTBP1-up_4052 SERPINE1-down_5054|TGFB3-up_7043 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|SMAD6-down_4091 SERPINE1-down_5054|TGFB3-up_7043 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS1-down_7057 TFPI-down_7035
hsa04350	hsa04630	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0.015	ID1-down CCND1-up|SMAD6-down CCND1-up|TGFB3-up CCND1-up|THBS1-down CCND1-up|SMAD6-down CCND2-up|TGFB3-up CCND2-up|THBS1-down CCND2-up|SMAD6-down JAK1-down|THBS1-down MCL1-down|THBS1-down SOCS3-down	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|THBS1-down_7057 CCND1-up_595|SMAD6-down_4091 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|THBS1-down_7057 CCND2-up_894|SMAD6-down_4091 JAK1-down_3716|THBS1-down_7057 MCL1-down_4170|THBS1-down_7057 SOCS3-down_9021
hsa04350	hsa04670	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	THBS1-down CLDN1-up|THBS1-down CLDN5-down|ID1-down CXCL12-up|TGFB3-up CXCL12-up|THBS1-down CXCL12-up|ID1-down MMP2-up|ID1-down THY1-up|LTBP1-up MMP2-up|SMAD6-down MMP2-up|TGFB3-up MMP2-up|THBS1-down MMP2-up|TGFB3-up THY1-up|TGFB3-up VCAM1-up|THBS1-down THY1-up|THBS1-down VCAM1-up	THBS1-down_7057 CLDN1-up_9076|THBS1-down_7057 CLDN5-down_7122|ID1-down_3397 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THY1-up_7070|LTBP1-up_4052 MMP2-up_4313|SMAD6-down_4091 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|TGFB3-up_7043 THY1-up_7070|TGFB3-up_7043 VCAM1-up_7412|THBS1-down_7057 THY1-up_7070|THBS1-down_7057 VCAM1-up_7412
hsa04350	hsa04915	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	LTBP1-up HBEGF-down|TGFB3-up HBEGF-down|THBS1-down HBEGF-down|NBL1-up HSPA1A-down|ID1-down JUN-down|ID1-down MMP2-up|SMAD6-down JUN-down|TGFB3-up JUN-down|THBS1-down JUN-down|LTBP1-up MMP2-up|SMAD6-down MMP2-up|TGFB3-up MMP2-up|THBS1-down MMP2-up	LTBP1-up_4052 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|THBS1-down_7057 HBEGF-down_1839|NBL1-up_4681 HSPA1A-down_3303|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|SMAD6-down_4091 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|THBS1-down_7057 JUN-down_3725|LTBP1-up_4052 MMP2-up_4313|SMAD6-down_4091 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313
hsa04350	hsa04933	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	ID1-down CCND1-up|SMAD6-down CCND1-up|THBS1-down CCND1-up|LTBP1-up COL1A1-up|SMAD6-down COL1A1-up|THBS1-down COL1A1-up|LTBP1-up COL1A2-up|SMAD6-down COL1A2-up|THBS1-down COL1A2-up|LTBP1-up COL3A1-up|THBS1-down COL3A1-up|THBS1-down F3-down|THBS1-down FIGF-down|ID1-down JUN-down|ID1-down MMP2-up|ID1-down SERPINE1-down|ID1-down TGFB3-up|SMAD6-down JUN-down|THBS1-down JUN-down|LTBP1-up MMP2-up|LTBP1-up SERPINE1-down|LTBP1-up TGFB3-up|SMAD6-down MMP2-up|THBS1-down MMP2-up|SMAD6-down SERPINE1-down|THBS1-down SERPINE1-down|SMAD6-down TGFB3-up|TGFB3-up THBS1-down|THBS1-down VCAM1-up	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|THBS1-down_7057 CCND1-up_595|LTBP1-up_4052 COL1A1-up_1277|SMAD6-down_4091 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|LTBP1-up_4052 COL1A2-up_1278|SMAD6-down_4091 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|LTBP1-up_4052 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS1-down_7057 F3-down_2152|THBS1-down_7057 FIGF-down_2277|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|ID1-down_3397 SERPINE1-down_5054|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 JUN-down_3725|THBS1-down_7057 JUN-down_3725|LTBP1-up_4052 MMP2-up_4313|LTBP1-up_4052 SERPINE1-down_5054|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|SMAD6-down_4091 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057|THBS1-down_7057 VCAM1-up_7412
hsa04350	hsa04974	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	TGFB3-up COL10A1-up|THBS1-down COL10A1-up|TGFB3-up COL14A1-up|THBS1-down COL14A1-up|LTBP1-up COL15A1-up|THBS1-down COL15A1-up|THBS1-down COL17A1-up|TGFB3-up COL18A1-up|THBS1-down COL18A1-up|LTBP1-up COL1A1-up|SMAD6-down COL1A1-up|TGFB3-up COL1A1-up|THBS1-down COL1A1-up|LTBP1-up COL1A2-up|SMAD6-down COL1A2-up|TGFB3-up COL1A2-up|THBS1-down COL1A2-up|LTBP1-up COL3A1-up|TGFB3-up COL3A1-up|THBS1-down COL3A1-up|LTBP1-up COL5A1-up|TGFB3-up COL5A1-up|THBS1-down COL5A1-up|TGFB3-up COL5A2-up|THBS1-down COL5A2-up|LTBP1-up COL6A1-up|TGFB3-up COL6A1-up|THBS1-down COL6A1-up|TGFB3-up COL6A3-up|THBS1-down COL6A3-up|SMAD6-down COL7A1-up|THBS1-down COL7A1-up|THBS1-down MME-down|NBL1-up SLC1A1-down	TGFB3-up_7043 COL10A1-up_1300|THBS1-down_7057 COL10A1-up_1300|TGFB3-up_7043 COL14A1-up_7373|THBS1-down_7057 COL14A1-up_7373|LTBP1-up_4052 COL15A1-up_1306|THBS1-down_7057 COL15A1-up_1306|THBS1-down_7057 COL17A1-up_1308|TGFB3-up_7043 COL18A1-up_80781|THBS1-down_7057 COL18A1-up_80781|LTBP1-up_4052 COL1A1-up_1277|SMAD6-down_4091 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|LTBP1-up_4052 COL1A2-up_1278|SMAD6-down_4091 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|LTBP1-up_4052 COL3A1-up_1281|TGFB3-up_7043 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|LTBP1-up_4052 COL5A1-up_1289|TGFB3-up_7043 COL5A1-up_1289|THBS1-down_7057 COL5A1-up_1289|TGFB3-up_7043 COL5A2-up_1290|THBS1-down_7057 COL5A2-up_1290|LTBP1-up_4052 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|THBS1-down_7057 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|THBS1-down_7057 COL6A3-up_1293|SMAD6-down_4091 COL7A1-up_1294|THBS1-down_7057 COL7A1-up_1294|THBS1-down_7057 MME-down_4311|NBL1-up_4681 SLC1A1-down_6505
hsa04350	hsa05145	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0	NBL1-up HSPA1A-down|ID1-down TGFB3-up|SMAD6-down JAK1-down|LTBP1-up LAMA3-down|THBS1-down LAMA3-down|SMAD6-down LDLR-down|THBS1-down LDLR-down|LTBP1-up TGFB3-up|SMAD6-down TGFB3-up|TGFB3-up THBS1-down	NBL1-up_4681 HSPA1A-down_3303|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 JAK1-down_3716|LTBP1-up_4052 LAMA3-down_3909|THBS1-down_7057 LAMA3-down_3909|SMAD6-down_4091 LDLR-down_3949|THBS1-down_7057 LDLR-down_3949|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057
hsa04350	hsa05146	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	LTBP1-up COL1A1-up|SMAD6-down COL1A1-up|THBS1-down COL1A1-up|LTBP1-up COL1A2-up|SMAD6-down COL1A2-up|THBS1-down COL1A2-up|LTBP1-up COL3A1-up|THBS1-down COL3A1-up|ID1-down TGFB3-up|LTBP1-up LAMA3-down|THBS1-down LAMA3-down|LTBP1-up TGFB3-up|SMAD6-down TGFB3-up|TGFB3-up THBS1-down	LTBP1-up_4052 COL1A1-up_1277|SMAD6-down_4091 COL1A1-up_1277|THBS1-down_7057 COL1A1-up_1277|LTBP1-up_4052 COL1A2-up_1278|SMAD6-down_4091 COL1A2-up_1278|THBS1-down_7057 COL1A2-up_1278|LTBP1-up_4052 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|ID1-down_3397 TGFB3-up_7043|LTBP1-up_4052 LAMA3-down_3909|THBS1-down_7057 LAMA3-down_3909|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057
hsa04350	hsa05152	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.006	THBS1-down CD74-up|ID1-down TGFB3-up|SMAD6-down JAK1-down|LTBP1-up TGFB3-up|SMAD6-down TGFB3-up|TGFB3-up THBS1-down	THBS1-down_7057 CD74-up_972|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 JAK1-down_3716|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057
hsa04350	hsa05166	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.005	ID1-down CCND1-up|SMAD6-down CCND1-up|THBS1-down CCND1-up|SMAD6-down CCND2-up|THBS1-down CCND2-up|ID1-down JUN-down|ID1-down MYB-up|ID1-down PDGFRA-down|ID1-down TGFB3-up|SMAD6-down JAK1-down|SMAD6-down JUN-down|THBS1-down JUN-down|LTBP1-up PDGFRA-down|LTBP1-up TGFB3-up|THBS1-down MYB-up|THBS1-down PDGFRA-down|SMAD6-down TGFB3-up|TGFB3-up THBS1-down|THBS1-down VCAM1-up	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|THBS1-down_7057 CCND1-up_595|SMAD6-down_4091 CCND2-up_894|THBS1-down_7057 CCND2-up_894|ID1-down_3397 JUN-down_3725|ID1-down_3397 MYB-up_4602|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 JAK1-down_3716|SMAD6-down_4091 JUN-down_3725|THBS1-down_7057 JUN-down_3725|LTBP1-up_4052 PDGFRA-down_5156|LTBP1-up_4052 TGFB3-up_7043|THBS1-down_7057 MYB-up_4602|THBS1-down_7057 PDGFRA-down_5156|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057|THBS1-down_7057 VCAM1-up_7412
hsa04350	hsa05200	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	ID1-down CCND1-up|SMAD6-down CCND1-up|THBS1-down CCND1-up|ID1-down CXCL12-up|THBS1-down CXCL12-up|THBS1-down EDNRB-down|THBS1-down FIGF-down|ID1-down IGF1-up|ID1-down JUN-down|ID1-down MMP1-up|ID1-down MMP2-up|ID1-down PDGFRA-down|ID1-down TGFB3-up|SMAD6-down IGF1-up|THBS1-down IGF1-up|SMAD6-down JAK1-down|SMAD6-down JUN-down|THBS1-down JUN-down|LTBP1-up LAMA3-down|THBS1-down LAMA3-down|LTBP1-up MMP1-up|LTBP1-up MMP2-up|LTBP1-up PDGFRA-down|LTBP1-up TGFB3-up|SMAD6-down MMP1-up|THBS1-down MMP1-up|SMAD6-down MMP2-up|THBS1-down MMP2-up|THBS1-down PDGFRA-down|SMAD6-down TCF7L2-up|SMAD6-down TGFB3-up|TGFB3-up THBS1-down|THBS1-down ZBTB16-down	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|THBS1-down_7057 CCND1-up_595|ID1-down_3397 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS1-down_7057 EDNRB-down_1910|THBS1-down_7057 FIGF-down_2277|ID1-down_3397 IGF1-up_3479|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP1-up_4312|ID1-down_3397 MMP2-up_4313|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|SMAD6-down_4091 JAK1-down_3716|SMAD6-down_4091 JUN-down_3725|THBS1-down_7057 JUN-down_3725|LTBP1-up_4052 LAMA3-down_3909|THBS1-down_7057 LAMA3-down_3909|LTBP1-up_4052 MMP1-up_4312|LTBP1-up_4052 MMP2-up_4313|LTBP1-up_4052 PDGFRA-down_5156|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|SMAD6-down_4091 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS1-down_7057 PDGFRA-down_5156|SMAD6-down_4091 TCF7L2-up_6934|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057|THBS1-down_7057 ZBTB16-down_7704
hsa04350	hsa05202	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	SMAD6-down CCND2-up|TGFB3-up CCND2-up|THBS1-down CCND2-up|ID1-down FLT1-down|SMAD6-down FLT1-down|TGFB3-up FLT1-down|THBS1-down FLT1-down|ID1-down IGF1-up|ID1-down PLAU-up|SMAD6-down IGF1-up|TGFB3-up IGF1-up|THBS1-down IGF1-up|TGFB3-up PLAU-up|THBS1-down PLAU-up|THBS1-down PROM1-up|TGFB3-up SIX1-up|THBS1-down ZBTB16-down	SMAD6-down_4091 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|THBS1-down_7057 CCND2-up_894|ID1-down_3397 FLT1-down_2321|SMAD6-down_4091 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|ID1-down_3397 IGF1-up_3479|ID1-down_3397 PLAU-up_5328|SMAD6-down_4091 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|TGFB3-up_7043 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS1-down_7057 PROM1-up_8842|TGFB3-up_7043 SIX1-up_6495|THBS1-down_7057 ZBTB16-down_7704
hsa04350	hsa05205	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.007	ID1-down CCND1-up|SMAD6-down CCND1-up|TGFB3-up CCND1-up|LTBP1-up HBEGF-down|TGFB3-up HBEGF-down|ID1-down IGF1-up|ID1-down MMP2-up|ID1-down PLAU-up|ID1-down THBS1-down|SMAD6-down IGF1-up|TGFB3-up IGF1-up|LTBP1-up MMP2-up|SMAD6-down MMP2-up|TGFB3-up MMP2-up|TGFB3-up PLAU-up|SMAD6-down THBS1-down	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|LTBP1-up_4052 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|ID1-down_3397 IGF1-up_3479|ID1-down_3397 MMP2-up_4313|ID1-down_3397 PLAU-up_5328|ID1-down_3397 THBS1-down_7057|SMAD6-down_4091 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|LTBP1-up_4052 MMP2-up_4313|SMAD6-down_4091 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|TGFB3-up_7043 PLAU-up_5328|SMAD6-down_4091 THBS1-down_7057
hsa04350	hsa05206	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.036	ID1-down CCND1-up|SMAD6-down CCND1-up|TGFB3-up CCND1-up|SMAD6-down CCND2-up|TGFB3-up CCND2-up|SMAD6-down HMOX1-down|ID1-down PDGFRA-down|ID1-down PLAU-up|ID1-down THBS1-down|LTBP1-up PDGFRA-down|TGFB3-up PDGFRA-down|TGFB3-up PLAU-up|SMAD6-down SOX4-up|SMAD6-down THBS1-down|SMAD6-down TNC-up|TGFB3-up TNC-up|TGFB3-up TP63-up	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|SMAD6-down_4091 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|SMAD6-down_4091 HMOX1-down_3162|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 PLAU-up_5328|ID1-down_3397 THBS1-down_7057|LTBP1-up_4052 PDGFRA-down_5156|TGFB3-up_7043 PDGFRA-down_5156|TGFB3-up_7043 PLAU-up_5328|SMAD6-down_4091 SOX4-up_6659|SMAD6-down_4091 THBS1-down_7057|SMAD6-down_4091 TNC-up_3371|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa04350	hsa05219	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	ID1-down CCND1-up|SMAD6-down CCND1-up|TGFB3-up CCND1-up|LTBP1-up HBEGF-down|TGFB3-up HBEGF-down|ID1-down MMP1-up|ID1-down MMP2-up|ID1-down THBS1-down|LTBP1-up MMP1-up|LTBP1-up MMP2-up|SMAD6-down MMP1-up|TGFB3-up MMP1-up|SMAD6-down MMP2-up|TGFB3-up MMP2-up|SMAD6-down THBS1-down	ID1-down_3397 CCND1-up_595|SMAD6-down_4091 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|LTBP1-up_4052 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|ID1-down_3397 MMP1-up_4312|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THBS1-down_7057|LTBP1-up_4052 MMP1-up_4312|LTBP1-up_4052 MMP2-up_4313|SMAD6-down_4091 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|SMAD6-down_4091 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|SMAD6-down_4091 THBS1-down_7057
hsa04350	hsa05323	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	THBS1-down CTSK-up|ID1-down CXCL12-up|THBS1-down CXCL12-up|ID1-down FLT1-down|SMAD6-down FLT1-down|THBS1-down FLT1-down|ID1-down JUN-down|ID1-down MMP1-up|ID1-down TGFB3-up|SMAD6-down JUN-down|THBS1-down JUN-down|LTBP1-up MMP1-up|LTBP1-up TGFB3-up|SMAD6-down MMP1-up|THBS1-down MMP1-up|SMAD6-down TGFB3-up|TGFB3-up THBS1-down	THBS1-down_7057 CTSK-up_1513|ID1-down_3397 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|ID1-down_3397 FLT1-down_2321|SMAD6-down_4091 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP1-up_4312|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 JUN-down_3725|THBS1-down_7057 JUN-down_3725|LTBP1-up_4052 MMP1-up_4312|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057
hsa04350	hsa05410	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.005	ID1-down IGF1-up|ID1-down TGFB3-up|SMAD6-down IGF1-up|THBS1-down IGF1-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|LTBP1-up TGFB3-up|SMAD6-down TGFB3-up|TGFB3-up THBS1-down	ID1-down_3397 IGF1-up_3479|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057
hsa04350	hsa05412	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.002	SMAD6-down CDH2-up|TGFB3-up CDH2-up|THBS1-down CDH2-up|TGFB3-up DES-up|THBS1-down ITGB4-up|TGFB3-up ITGB8-up|THBS1-down ITGB8-up|SMAD6-down TCF7L2-up|TGFB3-up TCF7L2-up	SMAD6-down_4091 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|THBS1-down_7057 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|THBS1-down_7057 ITGB8-up_3696|SMAD6-down_4091 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934
hsa04350	hsa05414	TGF-beta signaling pathway - Homo sapiens (human)	ID1,SMAD6,THBS1,LTBP1,NBL1,TGFB3	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.007	ID1-down IGF1-up|ID1-down TGFB3-up|SMAD6-down IGF1-up|THBS1-down IGF1-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|LTBP1-up TGFB3-up|SMAD6-down TGFB3-up|TGFB3-up THBS1-down	ID1-down_3397 IGF1-up_3479|ID1-down_3397 TGFB3-up_7043|SMAD6-down_4091 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|LTBP1-up_4052 TGFB3-up_7043|SMAD6-down_4091 TGFB3-up_7043|TGFB3-up_7043 THBS1-down_7057
hsa04360	hsa04390	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0.031	CXCL12-up CCND1-up|EPHA3-up CCND1-up|CXCL12-up CCND2-up|CXCL12-up ID1-down|CXCL12-up SERPINE1-down|CXCL12-up SOX2-up|CXCL12-up TGFB3-up|EPHA3-up FZD5-down|EPHA3-up SOX2-up|EPHA3-up TCF7L2-up|RND1-down FZD5-down|NTN1-up TGFB3-up	CXCL12-up_6387 CCND1-up_595|EPHA3-up_2042 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 SOX2-up_6657|CXCL12-up_6387 TGFB3-up_7043|EPHA3-up_2042 FZD5-down_7855|EPHA3-up_2042 SOX2-up_6657|EPHA3-up_2042 TCF7L2-up_6934|RND1-down_27289 FZD5-down_7855|NTN1-up_9423 TGFB3-up_7043
hsa04360	hsa04510	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0.001	BOC-up FLT1-down|BOC-up JUN-down|CXCL12-up CCND1-up|EPHA3-up CCND1-up|CXCL12-up CCND2-up|CXCL12-up COL1A1-up|EPHA3-up COL1A1-up|CXCL12-up COL1A2-up|EPHA3-up COL1A2-up|CXCL12-up COMP-up|CXCL12-up FIGF-down|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up JUN-down|CXCL12-up PDGFRA-down|CXCL12-up SPP1-up|CXCL12-up THBS1-down|CXCL12-up THBS2-up|CXCL12-up TNC-up|EPHA3-up IGF1-up|EPHA3-up JUN-down|EPHA3-up PDGFRA-down|NTN1-up FLT1-down|RND1-down FLT1-down|ROBO2-up FLT1-down|SEMA3E-down FLT1-down|NTN1-up IGF1-up|NTN1-up JUN-down|RND1-down JUN-down|NTN1-up PDGFRA-down|NTN1-up THBS1-down|NTN1-up THBS2-up|NTN1-up TNC-up|RND1-down PDGFRA-down|ROBO2-up PDGFRA-down|SEMA3E-down THBS1-down	BOC-up_91653 FLT1-down_2321|BOC-up_91653 JUN-down_3725|CXCL12-up_6387 CCND1-up_595|EPHA3-up_2042 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL12-up_6387 COL1A1-up_1277|EPHA3-up_2042 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|EPHA3-up_2042 COL1A2-up_1278|CXCL12-up_6387 COMP-up_1311|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 SPP1-up_6696|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 THBS2-up_7058|CXCL12-up_6387 TNC-up_3371|EPHA3-up_2042 IGF1-up_3479|EPHA3-up_2042 JUN-down_3725|EPHA3-up_2042 PDGFRA-down_5156|NTN1-up_9423 FLT1-down_2321|RND1-down_27289 FLT1-down_2321|ROBO2-up_6092 FLT1-down_2321|SEMA3E-down_9723 FLT1-down_2321|NTN1-up_9423 IGF1-up_3479|NTN1-up_9423 JUN-down_3725|RND1-down_27289 JUN-down_3725|NTN1-up_9423 PDGFRA-down_5156|NTN1-up_9423 THBS1-down_7057|NTN1-up_9423 THBS2-up_7058|NTN1-up_9423 TNC-up_3371|RND1-down_27289 PDGFRA-down_5156|ROBO2-up_6092 PDGFRA-down_5156|SEMA3E-down_9723 THBS1-down_7057
hsa04360	hsa04514	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	BOC-up CDH2-up|CXCL12-up CD274-down|CXCL12-up CDH2-up|EPHA3-up CDH2-up|NTN1-up CDH2-up|RND1-down CDH2-up|ROBO2-up CDH2-up|CXCL12-up CLDN5-down|CXCL12-up NCAM1-up|CXCL12-up SELL-down|CXCL12-up VCAM1-up|CXCL12-up VTCN1-up|EPHA3-up NCAM1-up|EPHA3-up VCAM1-up|NTN1-up NCAM1-up|SEMA3E-down NCAM1-up|NTN1-up NFASC-up|SEMA3E-down NFASC-up	BOC-up_91653 CDH2-up_1000|CXCL12-up_6387 CD274-down_29126|CXCL12-up_6387 CDH2-up_1000|EPHA3-up_2042 CDH2-up_1000|NTN1-up_9423 CDH2-up_1000|RND1-down_27289 CDH2-up_1000|ROBO2-up_6092 CDH2-up_1000|CXCL12-up_6387 CLDN5-down_7122|CXCL12-up_6387 NCAM1-up_4684|CXCL12-up_6387 SELL-down_6402|CXCL12-up_6387 VCAM1-up_7412|CXCL12-up_6387 VTCN1-up_79679|EPHA3-up_2042 NCAM1-up_4684|EPHA3-up_2042 VCAM1-up_7412|NTN1-up_9423 NCAM1-up_4684|SEMA3E-down_9723 NCAM1-up_4684|NTN1-up_9423 NFASC-up_23114|SEMA3E-down_9723 NFASC-up_23114
hsa04360	hsa04550	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.004	CXCL12-up ID1-down|CXCL12-up IGF1-up|CXCL12-up JAK1-down|CXCL12-up LIFR-down|CXCL12-up SOX2-up|EPHA3-up FZD5-down|EPHA3-up IGF1-up|EPHA3-up JAK1-down|EPHA3-up SOX2-up|RND1-down FZD5-down|NTN1-up IGF1-up|RND1-down JAK1-down	CXCL12-up_6387 ID1-down_3397|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 SOX2-up_6657|EPHA3-up_2042 FZD5-down_7855|EPHA3-up_2042 IGF1-up_3479|EPHA3-up_2042 JAK1-down_3716|EPHA3-up_2042 SOX2-up_6657|RND1-down_27289 FZD5-down_7855|NTN1-up_9423 IGF1-up_3479|RND1-down_27289 JAK1-down_3716
hsa04360	hsa04630	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0.044	BOC-up MCL1-down|CXCL12-up CCND1-up|EPHA3-up CCND1-up|CXCL12-up CCND2-up|CXCL12-up CSF3R-down|CXCL12-up JAK1-down|CXCL12-up LIFR-down|CXCL12-up MCL1-down|CXCL12-up SOCS3-down|EPHA3-up JAK1-down|RND1-down JAK1-down	BOC-up_91653 MCL1-down_4170|CXCL12-up_6387 CCND1-up_595|EPHA3-up_2042 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL12-up_6387 CSF3R-down_1441|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LIFR-down_3977|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 SOCS3-down_9021|EPHA3-up_2042 JAK1-down_3716|RND1-down_27289 JAK1-down_3716
hsa04360	hsa05166	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.015	BOC-up JUN-down|CXCL12-up CCND1-up|EPHA3-up CCND1-up|CXCL12-up CCND2-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up MYB-up|CXCL12-up PDGFRA-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|EPHA3-up FZD5-down|EPHA3-up JAK1-down|EPHA3-up JUN-down|EPHA3-up PDGFRA-down|EPHA3-up VCAM1-up|RND1-down FZD5-down|RND1-down JAK1-down|NTN1-up JUN-down|RND1-down JUN-down|NTN1-up PDGFRA-down|NTN1-up TGFB3-up|RND1-down PDGFRA-down|ROBO2-up PDGFRA-down	BOC-up_91653 JUN-down_3725|CXCL12-up_6387 CCND1-up_595|EPHA3-up_2042 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|EPHA3-up_2042 FZD5-down_7855|EPHA3-up_2042 JAK1-down_3716|EPHA3-up_2042 JUN-down_3725|EPHA3-up_2042 PDGFRA-down_5156|EPHA3-up_2042 VCAM1-up_7412|RND1-down_27289 FZD5-down_7855|RND1-down_27289 JAK1-down_3716|NTN1-up_9423 JUN-down_3725|RND1-down_27289 JUN-down_3725|NTN1-up_9423 PDGFRA-down_5156|NTN1-up_9423 TGFB3-up_7043|RND1-down_27289 PDGFRA-down_5156|ROBO2-up_6092 PDGFRA-down_5156
hsa04360	hsa05202	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.003	BOC-up FLT1-down|CXCL12-up CCND2-up|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up PLAU-up|CXCL12-up PROM1-up|CXCL12-up ZBTB16-down|EPHA3-up IGF1-up|EPHA3-up PROM1-up|EPHA3-up ZBTB16-down|NTN1-up FLT1-down|RND1-down FLT1-down|ROBO2-up FLT1-down|SEMA3E-down FLT1-down|NTN1-up IGF1-up|RND1-down NFKBIZ-down|RND1-down PLAU-up|RND1-down ZBTB16-down|ROBO2-up SIX1-up	BOC-up_91653 FLT1-down_2321|CXCL12-up_6387 CCND2-up_894|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 PROM1-up_8842|CXCL12-up_6387 ZBTB16-down_7704|EPHA3-up_2042 IGF1-up_3479|EPHA3-up_2042 PROM1-up_8842|EPHA3-up_2042 ZBTB16-down_7704|NTN1-up_9423 FLT1-down_2321|RND1-down_27289 FLT1-down_2321|ROBO2-up_6092 FLT1-down_2321|SEMA3E-down_9723 FLT1-down_2321|NTN1-up_9423 IGF1-up_3479|RND1-down_27289 NFKBIZ-down_64332|RND1-down_27289 PLAU-up_5328|RND1-down_27289 ZBTB16-down_7704|ROBO2-up_6092 SIX1-up_6495
hsa04360	hsa05205	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.026	EPHA3-up ANK2-up|CXCL12-up CCND1-up|EPHA3-up CCND1-up|CXCL12-up HBEGF-down|CXCL12-up IGF1-up|CXCL12-up MMP2-up|CXCL12-up PLAU-up|CXCL12-up THBS1-down|EPHA3-up FZD5-down|EPHA3-up IGF1-up|EPHA3-up MMP2-up|RND1-down FZD5-down|NTN1-up IGF1-up|NTN1-up MMP2-up|NTN1-up THBS1-down|RND1-down PLAU-up|SEMA3E-down THBS1-down	EPHA3-up_2042 ANK2-up_287|CXCL12-up_6387 CCND1-up_595|EPHA3-up_2042 CCND1-up_595|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 THBS1-down_7057|EPHA3-up_2042 FZD5-down_7855|EPHA3-up_2042 IGF1-up_3479|EPHA3-up_2042 MMP2-up_4313|RND1-down_27289 FZD5-down_7855|NTN1-up_9423 IGF1-up_3479|NTN1-up_9423 MMP2-up_4313|NTN1-up_9423 THBS1-down_7057|RND1-down_27289 PLAU-up_5328|SEMA3E-down_9723 THBS1-down_7057
hsa04360	hsa05206	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.011	BOC-up MCL1-down|CXCL12-up CCND1-up|EPHA3-up CCND1-up|CXCL12-up CCND2-up|CXCL12-up HMOX1-down|CXCL12-up MCL1-down|CXCL12-up MMP16-up|CXCL12-up PDGFRA-down|CXCL12-up PLAU-up|CXCL12-up SERPINB5-up|CXCL12-up SOX4-up|CXCL12-up THBS1-down|CXCL12-up TNC-up|EPHA3-up HMOX1-down|EPHA3-up PDGFRA-down|NTN1-up PDGFRA-down|NTN1-up THBS1-down|NTN1-up TNC-up|RND1-down PDGFRA-down|ROBO2-up PDGFRA-down|RND1-down PLAU-up|RND1-down TP63-up|SEMA3E-down THBS1-down	BOC-up_91653 MCL1-down_4170|CXCL12-up_6387 CCND1-up_595|EPHA3-up_2042 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MMP16-up_4325|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SOX4-up_6659|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 TNC-up_3371|EPHA3-up_2042 HMOX1-down_3162|EPHA3-up_2042 PDGFRA-down_5156|NTN1-up_9423 PDGFRA-down_5156|NTN1-up_9423 THBS1-down_7057|NTN1-up_9423 TNC-up_3371|RND1-down_27289 PDGFRA-down_5156|ROBO2-up_6092 PDGFRA-down_5156|RND1-down_27289 PLAU-up_5328|RND1-down_27289 TP63-up_8626|SEMA3E-down_9723 THBS1-down_7057
hsa04360	hsa05412	Axon guidance - Homo sapiens (human)	RND1,SEMA3E,BOC,CXCL12,EPHA3,NTN1,ROBO2	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.026	BOC-up CDH2-up|CXCL12-up CDH2-up|EPHA3-up CDH2-up|NTN1-up CDH2-up|RND1-down CDH2-up|ROBO2-up CDH2-up|EPHA3-up TCF7L2-up	BOC-up_91653 CDH2-up_1000|CXCL12-up_6387 CDH2-up_1000|EPHA3-up_2042 CDH2-up_1000|NTN1-up_9423 CDH2-up_1000|RND1-down_27289 CDH2-up_1000|ROBO2-up_6092 CDH2-up_1000|EPHA3-up_2042 TCF7L2-up_6934
hsa04380	hsa04390	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	0	CTSK-up CCND1-up|FHL2-up CCND1-up|FOSL2-down CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|FOSL2-down CCND2-up|JAK1-down CCND2-up|JUN-down CCND2-up|SOCS3-down CCND2-up|CTSK-up SERPINE1-down|FHL2-up SERPINE1-down|FOSL2-down SERPINE1-down|FOSL2-down SOX2-up|FOSL2-down TCF7L2-up|FOSL2-down TGFB3-up|JUN-down FZD5-down|JUN-down ID1-down|JAK1-down SERPINE1-down|JUN-down SERPINE1-down|JUN-down SOX2-up|JUN-down TCF7L2-up|JUN-down TGFB3-up|SOCS3-down SERPINE1-down|SOCS3-down SOX2-up	CTSK-up_1513 CCND1-up_595|FHL2-up_2274 CCND1-up_595|FOSL2-down_2355 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|FOSL2-down_2355 CCND2-up_894|JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CTSK-up_1513 SERPINE1-down_5054|FHL2-up_2274 SERPINE1-down_5054|FOSL2-down_2355 SERPINE1-down_5054|FOSL2-down_2355 SOX2-up_6657|FOSL2-down_2355 TCF7L2-up_6934|FOSL2-down_2355 TGFB3-up_7043|JUN-down_3725 FZD5-down_7855|JUN-down_3725 ID1-down_3397|JAK1-down_3716 SERPINE1-down_5054|JUN-down_3725 SERPINE1-down_5054|JUN-down_3725 SOX2-up_6657|JUN-down_3725 TCF7L2-up_6934|JUN-down_3725 TGFB3-up_7043|SOCS3-down_9021 SERPINE1-down_5054|SOCS3-down_9021 SOX2-up_6657
hsa04380	hsa04510	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CTSK-up CCND1-up|FHL2-up CCND1-up|FOSL2-down CCND1-up|JAK1-down CCND1-up|SOCS3-down CCND1-up|FOSL2-down CCND2-up|JAK1-down CCND2-up|SOCS3-down CCND2-up|CTSK-up COL1A1-up|FOSL2-down COL1A1-up|SOCS3-down COL1A1-up|CTSK-up COL1A2-up|FOSL2-down COL1A2-up|JAK1-down COL1A2-up|CTSK-up COL6A1-up|CTSK-up COL6A3-up|CTSK-up COMP-up|FHL2-up COMP-up|CTSK-up IGF1-up|CTSK-up SPP1-up|CTSK-up THBS1-down|CTSK-up THBS2-up|CTSK-up TNC-up|FHL2-up IGF1-up|FHL2-up TNC-up|FOSL2-down FLT1-down|JAK1-down FLT1-down|SOCS3-down FLT1-down|FOSL2-down IGF1-up|FOSL2-down JUN-down|FOSL2-down LAMA3-down|JAK1-down IGF1-up|SOCS3-down IGF1-up|JAK1-down JUN-down|JAK1-down PDGFRA-down|SOCS3-down PDGFRA-down|SOCS3-down SPP1-up|SOCS3-down THBS1-down|SOCS3-down TNC-up	CTSK-up_1513 CCND1-up_595|FHL2-up_2274 CCND1-up_595|FOSL2-down_2355 CCND1-up_595|JAK1-down_3716 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|FOSL2-down_2355 CCND2-up_894|JAK1-down_3716 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CTSK-up_1513 COL1A1-up_1277|FOSL2-down_2355 COL1A1-up_1277|SOCS3-down_9021 COL1A1-up_1277|CTSK-up_1513 COL1A2-up_1278|FOSL2-down_2355 COL1A2-up_1278|JAK1-down_3716 COL1A2-up_1278|CTSK-up_1513 COL6A1-up_1291|CTSK-up_1513 COL6A3-up_1293|CTSK-up_1513 COMP-up_1311|FHL2-up_2274 COMP-up_1311|CTSK-up_1513 IGF1-up_3479|CTSK-up_1513 SPP1-up_6696|CTSK-up_1513 THBS1-down_7057|CTSK-up_1513 THBS2-up_7058|CTSK-up_1513 TNC-up_3371|FHL2-up_2274 IGF1-up_3479|FHL2-up_2274 TNC-up_3371|FOSL2-down_2355 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|FOSL2-down_2355 IGF1-up_3479|FOSL2-down_2355 JUN-down_3725|FOSL2-down_2355 LAMA3-down_3909|JAK1-down_3716 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 PDGFRA-down_5156|SOCS3-down_9021 PDGFRA-down_5156|SOCS3-down_9021 SPP1-up_6696|SOCS3-down_9021 THBS1-down_7057|SOCS3-down_9021 TNC-up_3371
hsa04380	hsa04512	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CTSK-up COL1A1-up|FOSL2-down COL1A1-up|JUN-down COL1A1-up|SOCS3-down COL1A1-up|CTSK-up COL1A2-up|FOSL2-down COL1A2-up|JAK1-down COL1A2-up|JUN-down COL1A2-up|CTSK-up COL6A1-up|JUN-down COL6A1-up|CTSK-up COL6A3-up|JUN-down COL6A3-up|CTSK-up COMP-up|FHL2-up COMP-up|JUN-down COMP-up|CTSK-up SPP1-up|CTSK-up THBS1-down|CTSK-up THBS2-up|CTSK-up TNC-up|FHL2-up TNC-up|FOSL2-down LAMA3-down|JUN-down ITGB4-up|JUN-down LAMA3-down|JUN-down SPP1-up|JUN-down THBS1-down|JUN-down THBS2-up|JUN-down TNC-up|SOCS3-down SPP1-up|SOCS3-down THBS1-down|SOCS3-down TNC-up	CTSK-up_1513 COL1A1-up_1277|FOSL2-down_2355 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|SOCS3-down_9021 COL1A1-up_1277|CTSK-up_1513 COL1A2-up_1278|FOSL2-down_2355 COL1A2-up_1278|JAK1-down_3716 COL1A2-up_1278|JUN-down_3725 COL1A2-up_1278|CTSK-up_1513 COL6A1-up_1291|JUN-down_3725 COL6A1-up_1291|CTSK-up_1513 COL6A3-up_1293|JUN-down_3725 COL6A3-up_1293|CTSK-up_1513 COMP-up_1311|FHL2-up_2274 COMP-up_1311|JUN-down_3725 COMP-up_1311|CTSK-up_1513 SPP1-up_6696|CTSK-up_1513 THBS1-down_7057|CTSK-up_1513 THBS2-up_7058|CTSK-up_1513 TNC-up_3371|FHL2-up_2274 TNC-up_3371|FOSL2-down_2355 LAMA3-down_3909|JUN-down_3725 ITGB4-up_3691|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SPP1-up_6696|JUN-down_3725 THBS1-down_7057|JUN-down_3725 THBS2-up_7058|JUN-down_3725 TNC-up_3371|SOCS3-down_9021 SPP1-up_6696|SOCS3-down_9021 THBS1-down_7057|SOCS3-down_9021 TNC-up_3371
hsa04380	hsa04514	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0.006	LILRB2-down CD274-down|SOCS3-down CD274-down|FHL2-up CDH2-up|JAK1-down CDH2-up|JUN-down CDH2-up|SOCS3-down CDH2-up|JUN-down CLDN5-down|CTSK-up VCAM1-up|FHL2-up VCAM1-up|JAK1-down NCAM1-up|JAK1-down SELL-down|JAK1-down VCAM1-up|JUN-down NCAM1-up|JUN-down SELL-down|JUN-down VCAM1-up|SOCS3-down NCAM1-up|SOCS3-down SELL-down|SOCS3-down VCAM1-up	LILRB2-down_10288 CD274-down_29126|SOCS3-down_9021 CD274-down_29126|FHL2-up_2274 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|SOCS3-down_9021 CDH2-up_1000|JUN-down_3725 CLDN5-down_7122|CTSK-up_1513 VCAM1-up_7412|FHL2-up_2274 VCAM1-up_7412|JAK1-down_3716 NCAM1-up_4684|JAK1-down_3716 SELL-down_6402|JAK1-down_3716 VCAM1-up_7412|JUN-down_3725 NCAM1-up_4684|JUN-down_3725 SELL-down_6402|JUN-down_3725 VCAM1-up_7412|SOCS3-down_9021 NCAM1-up_4684|SOCS3-down_9021 SELL-down_6402|SOCS3-down_9021 VCAM1-up_7412
hsa04380	hsa04550	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.005	CTSK-up IGF1-up|FHL2-up IGF1-up|FOSL2-down IGF1-up|FOSL2-down JAK1-down|FOSL2-down LIFR-down|FOSL2-down SOX2-up|JUN-down FZD5-down|JUN-down ID1-down|JUN-down IGF1-up|SOCS3-down IGF1-up|JUN-down LIFR-down|JUN-down SOX2-up|SOCS3-down LIFR-down|SOCS3-down SOX2-up	CTSK-up_1513 IGF1-up_3479|FHL2-up_2274 IGF1-up_3479|FOSL2-down_2355 IGF1-up_3479|FOSL2-down_2355 JAK1-down_3716|FOSL2-down_2355 LIFR-down_3977|FOSL2-down_2355 SOX2-up_6657|JUN-down_3725 FZD5-down_7855|JUN-down_3725 ID1-down_3397|JUN-down_3725 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|JUN-down_3725 LIFR-down_3977|JUN-down_3725 SOX2-up_6657|SOCS3-down_9021 LIFR-down_3977|SOCS3-down_9021 SOX2-up_6657
hsa04380	hsa04670	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0.003	JUN-down CLDN5-down|CTSK-up CXCL12-up|CTSK-up MMP2-up|CTSK-up VCAM1-up|JAK1-down CXCL12-up|JUN-down CXCL12-up|SOCS3-down CXCL12-up|FHL2-up VCAM1-up|FOSL2-down MMP2-up|JAK1-down MMP2-up|JAK1-down VCAM1-up|JUN-down MMP2-up|JUN-down THY1-up|JUN-down VCAM1-up|SOCS3-down MMP2-up|SOCS3-down VCAM1-up	JUN-down_3725 CLDN5-down_7122|CTSK-up_1513 CXCL12-up_6387|CTSK-up_1513 MMP2-up_4313|CTSK-up_1513 VCAM1-up_7412|JAK1-down_3716 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|FHL2-up_2274 VCAM1-up_7412|FOSL2-down_2355 MMP2-up_4313|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 VCAM1-up_7412|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THY1-up_7070|JUN-down_3725 VCAM1-up_7412|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 VCAM1-up_7412
hsa04380	hsa04915	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.031	CTSK-up MMP2-up|FOSL2-down HBEGF-down|FOSL2-down JUN-down|FOSL2-down MMP2-up|JAK1-down GABBR2-up|SOCS3-down HBEGF-down|JAK1-down HSPA1A-down|JAK1-down HSPA1B-down|JAK1-down JUN-down|JAK1-down MMP2-up|SOCS3-down MMP2-up	CTSK-up_1513 MMP2-up_4313|FOSL2-down_2355 HBEGF-down_1839|FOSL2-down_2355 JUN-down_3725|FOSL2-down_2355 MMP2-up_4313|JAK1-down_3716 GABBR2-up_9568|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 HSPA1A-down_3303|JAK1-down_3716 HSPA1B-down_3304|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP2-up_4313|SOCS3-down_9021 MMP2-up_4313
hsa04380	hsa04933	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CTSK-up CCND1-up|FHL2-up CCND1-up|FOSL2-down CCND1-up|JAK1-down CCND1-up|SOCS3-down CCND1-up|CTSK-up COL1A1-up|FOSL2-down COL1A1-up|SOCS3-down COL1A1-up|CTSK-up COL1A2-up|FOSL2-down COL1A2-up|JAK1-down COL1A2-up|CTSK-up COL3A1-up|CTSK-up MMP2-up|CTSK-up SERPINE1-down|CTSK-up VCAM1-up|FHL2-up F3-down|SOCS3-down F3-down|FHL2-up SERPINE1-down|FHL2-up VCAM1-up|FOSL2-down JUN-down|FOSL2-down MMP2-up|FOSL2-down SERPINE1-down|FOSL2-down TGFB3-up|JAK1-down JUN-down|JAK1-down MMP2-up|JAK1-down SERPINE1-down|JAK1-down VCAM1-up|SOCS3-down MMP2-up|SOCS3-down SERPINE1-down|SOCS3-down VCAM1-up	CTSK-up_1513 CCND1-up_595|FHL2-up_2274 CCND1-up_595|FOSL2-down_2355 CCND1-up_595|JAK1-down_3716 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CTSK-up_1513 COL1A1-up_1277|FOSL2-down_2355 COL1A1-up_1277|SOCS3-down_9021 COL1A1-up_1277|CTSK-up_1513 COL1A2-up_1278|FOSL2-down_2355 COL1A2-up_1278|JAK1-down_3716 COL1A2-up_1278|CTSK-up_1513 COL3A1-up_1281|CTSK-up_1513 MMP2-up_4313|CTSK-up_1513 SERPINE1-down_5054|CTSK-up_1513 VCAM1-up_7412|FHL2-up_2274 F3-down_2152|SOCS3-down_9021 F3-down_2152|FHL2-up_2274 SERPINE1-down_5054|FHL2-up_2274 VCAM1-up_7412|FOSL2-down_2355 JUN-down_3725|FOSL2-down_2355 MMP2-up_4313|FOSL2-down_2355 SERPINE1-down_5054|FOSL2-down_2355 TGFB3-up_7043|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 SERPINE1-down_5054|JAK1-down_3716 VCAM1-up_7412|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 SERPINE1-down_5054|SOCS3-down_9021 VCAM1-up_7412
hsa04380	hsa04974	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CTSK-up COL14A1-up|JUN-down COL14A1-up|CTSK-up COL18A1-up|JUN-down COL18A1-up|CTSK-up COL1A1-up|FOSL2-down COL1A1-up|JUN-down COL1A1-up|SOCS3-down COL1A1-up|CTSK-up COL1A2-up|FOSL2-down COL1A2-up|JAK1-down COL1A2-up|JUN-down COL1A2-up|CTSK-up COL3A1-up|JUN-down COL3A1-up|CTSK-up COL5A1-up|JUN-down COL5A1-up|CTSK-up COL5A2-up|JUN-down COL5A2-up|CTSK-up COL6A1-up|JUN-down COL6A1-up|CTSK-up COL6A3-up|JUN-down COL6A3-up|JUN-down COL7A1-up|CTSK-up MME-down|JUN-down KCNN4-up|JUN-down MME-down|JUN-down PRSS1-up	CTSK-up_1513 COL14A1-up_7373|JUN-down_3725 COL14A1-up_7373|CTSK-up_1513 COL18A1-up_80781|JUN-down_3725 COL18A1-up_80781|CTSK-up_1513 COL1A1-up_1277|FOSL2-down_2355 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|SOCS3-down_9021 COL1A1-up_1277|CTSK-up_1513 COL1A2-up_1278|FOSL2-down_2355 COL1A2-up_1278|JAK1-down_3716 COL1A2-up_1278|JUN-down_3725 COL1A2-up_1278|CTSK-up_1513 COL3A1-up_1281|JUN-down_3725 COL3A1-up_1281|CTSK-up_1513 COL5A1-up_1289|JUN-down_3725 COL5A1-up_1289|CTSK-up_1513 COL5A2-up_1290|JUN-down_3725 COL5A2-up_1290|CTSK-up_1513 COL6A1-up_1291|JUN-down_3725 COL6A1-up_1291|CTSK-up_1513 COL6A3-up_1293|JUN-down_3725 COL6A3-up_1293|JUN-down_3725 COL7A1-up_1294|CTSK-up_1513 MME-down_4311|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MME-down_4311|JUN-down_3725 PRSS1-up_5644
hsa04380	hsa05146	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CTSK-up COL1A1-up|FOSL2-down COL1A1-up|JUN-down COL1A1-up|SOCS3-down COL1A1-up|CTSK-up COL1A2-up|FOSL2-down COL1A2-up|JAK1-down COL1A2-up|JUN-down COL1A2-up|CTSK-up COL3A1-up|JUN-down COL3A1-up|CTSK-up SERPINB3-up|FOSL2-down LAMA3-down|FOSL2-down TGFB3-up|SOCS3-down IL1R2-down|JUN-down LAMA3-down|JUN-down SERPINB3-up|JUN-down TGFB3-up	CTSK-up_1513 COL1A1-up_1277|FOSL2-down_2355 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|SOCS3-down_9021 COL1A1-up_1277|CTSK-up_1513 COL1A2-up_1278|FOSL2-down_2355 COL1A2-up_1278|JAK1-down_3716 COL1A2-up_1278|JUN-down_3725 COL1A2-up_1278|CTSK-up_1513 COL3A1-up_1281|JUN-down_3725 COL3A1-up_1281|CTSK-up_1513 SERPINB3-up_6317|FOSL2-down_2355 LAMA3-down_3909|FOSL2-down_2355 TGFB3-up_7043|SOCS3-down_9021 IL1R2-down_7850|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SERPINB3-up_6317|JUN-down_3725 TGFB3-up_7043
hsa04380	hsa05152	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.027	CTSK-up CD74-up|FHL2-up CD74-up|JUN-down CD74-up|SOCS3-down CD74-up|SOCS3-down CLEC4E-down|FOSL2-down JAK1-down|FOSL2-down TGFB3-up|JUN-down TGFB3-up	CTSK-up_1513 CD74-up_972|FHL2-up_2274 CD74-up_972|JUN-down_3725 CD74-up_972|SOCS3-down_9021 CD74-up_972|SOCS3-down_9021 CLEC4E-down_26253|FOSL2-down_2355 JAK1-down_3716|FOSL2-down_2355 TGFB3-up_7043|JUN-down_3725 TGFB3-up_7043
hsa04380	hsa05200	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.021	CTSK-up CCND1-up|FHL2-up CCND1-up|FOSL2-down CCND1-up|SOCS3-down CCND1-up|SOCS3-down CSF3R-down|CTSK-up CXCL12-up|CTSK-up EDNRB-down|CTSK-up IGF1-up|CTSK-up MMP1-up|CTSK-up MMP2-up|SOCS3-down CXCL12-up|FHL2-up IGF1-up|FHL2-up ZBTB16-down|FOSL2-down IGF1-up|FOSL2-down JAK1-down|FOSL2-down JUN-down|FOSL2-down LAMA3-down|FOSL2-down MMP1-up|FOSL2-down MMP2-up|FOSL2-down TCF7L2-up|FOSL2-down TGFB3-up|FOSL2-down ZBTB16-down|SOCS3-down IGF1-up|SOCS3-down MMP1-up|SOCS3-down MMP2-up|SOCS3-down PDGFRA-down	CTSK-up_1513 CCND1-up_595|FHL2-up_2274 CCND1-up_595|FOSL2-down_2355 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|SOCS3-down_9021 CSF3R-down_1441|CTSK-up_1513 CXCL12-up_6387|CTSK-up_1513 EDNRB-down_1910|CTSK-up_1513 IGF1-up_3479|CTSK-up_1513 MMP1-up_4312|CTSK-up_1513 MMP2-up_4313|SOCS3-down_9021 CXCL12-up_6387|FHL2-up_2274 IGF1-up_3479|FHL2-up_2274 ZBTB16-down_7704|FOSL2-down_2355 IGF1-up_3479|FOSL2-down_2355 JAK1-down_3716|FOSL2-down_2355 JUN-down_3725|FOSL2-down_2355 LAMA3-down_3909|FOSL2-down_2355 MMP1-up_4312|FOSL2-down_2355 MMP2-up_4313|FOSL2-down_2355 TCF7L2-up_6934|FOSL2-down_2355 TGFB3-up_7043|FOSL2-down_2355 ZBTB16-down_7704|SOCS3-down_9021 IGF1-up_3479|SOCS3-down_9021 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 PDGFRA-down_5156
hsa04380	hsa05202	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	FOSL2-down CCND2-up|JAK1-down CCND2-up|JUN-down CCND2-up|SOCS3-down CCND2-up|CTSK-up IGF1-up|FHL2-up IGF1-up|FHL2-up ZBTB16-down|FOSL2-down FLT1-down|JAK1-down FLT1-down|JUN-down FLT1-down|SOCS3-down FLT1-down|FOSL2-down IGF1-up|FOSL2-down NFKBIZ-down|FOSL2-down PLAU-up|FOSL2-down ZBTB16-down|JAK1-down IGF1-up|JUN-down IGF1-up|SOCS3-down IGF1-up|SOCS3-down IL1R2-down|JAK1-down PLAU-up|JAK1-down ZBTB16-down|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|SOCS3-down NFKBIZ-down|SOCS3-down PLAU-up	FOSL2-down_2355 CCND2-up_894|JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CTSK-up_1513 IGF1-up_3479|FHL2-up_2274 IGF1-up_3479|FHL2-up_2274 ZBTB16-down_7704|FOSL2-down_2355 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|FOSL2-down_2355 IGF1-up_3479|FOSL2-down_2355 NFKBIZ-down_64332|FOSL2-down_2355 PLAU-up_5328|FOSL2-down_2355 ZBTB16-down_7704|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|SOCS3-down_9021 IL1R2-down_7850|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|SOCS3-down_9021 NFKBIZ-down_64332|SOCS3-down_9021 PLAU-up_5328
hsa04380	hsa05205	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	JUN-down CAV2-down|CTSK-up CCND1-up|FHL2-up CCND1-up|FOSL2-down CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|CTSK-up IGF1-up|CTSK-up MMP2-up|CTSK-up THBS1-down|FHL2-up IGF1-up|JUN-down FLNC-up|FOSL2-down HBEGF-down|FOSL2-down IGF1-up|FOSL2-down MMP2-up|FOSL2-down PLAU-up|JUN-down FZD5-down|JUN-down HBEGF-down|SOCS3-down HBEGF-down|JAK1-down IGF1-up|JUN-down IGF1-up|SOCS3-down IGF1-up|JAK1-down MMP2-up|JAK1-down PLAU-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|SOCS3-down MMP2-up|SOCS3-down PLAU-up|SOCS3-down THBS1-down	JUN-down_3725 CAV2-down_858|CTSK-up_1513 CCND1-up_595|FHL2-up_2274 CCND1-up_595|FOSL2-down_2355 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CTSK-up_1513 IGF1-up_3479|CTSK-up_1513 MMP2-up_4313|CTSK-up_1513 THBS1-down_7057|FHL2-up_2274 IGF1-up_3479|JUN-down_3725 FLNC-up_2318|FOSL2-down_2355 HBEGF-down_1839|FOSL2-down_2355 IGF1-up_3479|FOSL2-down_2355 MMP2-up_4313|FOSL2-down_2355 PLAU-up_5328|JUN-down_3725 FZD5-down_7855|JUN-down_3725 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057
hsa04380	hsa05206	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CTSK-up CCND1-up|FHL2-up CCND1-up|FOSL2-down CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|FOSL2-down CCND2-up|JAK1-down CCND2-up|JUN-down CCND2-up|SOCS3-down CCND2-up|CTSK-up HMOX1-down|CTSK-up MCL1-down|CTSK-up SERPINB5-up|CTSK-up THBS1-down|CTSK-up TNC-up|JUN-down CYP24A1-up|SOCS3-down CYP24A1-up|FHL2-up TNC-up|FOSL2-down HMOX1-down|FOSL2-down MCL1-down|FOSL2-down MMP16-up|FOSL2-down PLAU-up|JAK1-down HMOX1-down|JUN-down HMOX1-down|SOCS3-down HMOX1-down|JAK1-down IRS2-down|JUN-down IRS2-down|SOCS3-down IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|SOCS3-down MCL1-down|SOCS3-down PDGFRA-down|SOCS3-down PLAU-up|SOCS3-down THBS1-down|SOCS3-down TNC-up	CTSK-up_1513 CCND1-up_595|FHL2-up_2274 CCND1-up_595|FOSL2-down_2355 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|FOSL2-down_2355 CCND2-up_894|JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CTSK-up_1513 HMOX1-down_3162|CTSK-up_1513 MCL1-down_4170|CTSK-up_1513 SERPINB5-up_5268|CTSK-up_1513 THBS1-down_7057|CTSK-up_1513 TNC-up_3371|JUN-down_3725 CYP24A1-up_1591|SOCS3-down_9021 CYP24A1-up_1591|FHL2-up_2274 TNC-up_3371|FOSL2-down_2355 HMOX1-down_3162|FOSL2-down_2355 MCL1-down_4170|FOSL2-down_2355 MMP16-up_4325|FOSL2-down_2355 PLAU-up_5328|JAK1-down_3716 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|SOCS3-down_9021 HMOX1-down_3162|JAK1-down_3716 IRS2-down_8660|JUN-down_3725 IRS2-down_8660|SOCS3-down_9021 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|SOCS3-down_9021 MCL1-down_4170|SOCS3-down_9021 PDGFRA-down_5156|SOCS3-down_9021 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057|SOCS3-down_9021 TNC-up_3371
hsa04380	hsa05219	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CTSK-up CCND1-up|FHL2-up CCND1-up|FOSL2-down CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|CTSK-up MMP1-up|CTSK-up MMP2-up|CTSK-up THBS1-down|FOSL2-down HBEGF-down|FOSL2-down MMP1-up|FOSL2-down MMP2-up|JUN-down HBEGF-down|SOCS3-down HBEGF-down|JAK1-down MMP1-up|JAK1-down MMP2-up|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|SOCS3-down MMP1-up|SOCS3-down MMP2-up|SOCS3-down THBS1-down	CTSK-up_1513 CCND1-up_595|FHL2-up_2274 CCND1-up_595|FOSL2-down_2355 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CTSK-up_1513 MMP1-up_4312|CTSK-up_1513 MMP2-up_4313|CTSK-up_1513 THBS1-down_7057|FOSL2-down_2355 HBEGF-down_1839|FOSL2-down_2355 MMP1-up_4312|FOSL2-down_2355 MMP2-up_4313|JUN-down_3725 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|SOCS3-down_9021 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 THBS1-down_7057
hsa04380	hsa05414	Osteoclast differentiation - Homo sapiens (human)	FOSL2,JAK1,JUN,LILRB2,SOCS3,CTSK,FHL2	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.036	CTSK-up IGF1-up|FHL2-up IGF1-up|FHL2-up PLN-up|FHL2-up TTN-down|FOSL2-down IGF1-up|FOSL2-down TGFB3-up|JAK1-down IGF1-up|JUN-down IGF1-up|SOCS3-down IGF1-up|JUN-down ITGB4-up|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down	CTSK-up_1513 IGF1-up_3479|FHL2-up_2274 IGF1-up_3479|FHL2-up_2274 PLN-up_5350|FHL2-up_2274 TTN-down_7273|FOSL2-down_2355 IGF1-up_3479|FOSL2-down_2355 TGFB3-up_7043|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273
hsa04390	hsa04510	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	0	SERPINE1-down CAV2-down|CCND1-up FZD5-down|CCND1-up ID1-down|CCND1-up SERPINE1-down|CCND2-up FZD5-down|CCND2-up SERPINE1-down|SERPINE1-down COL1A1-up|SOX2-up COL1A1-up|TCF7L2-up COL1A1-up|TGFB3-up COL1A1-up|SERPINE1-down COL1A2-up|SOX2-up COL1A2-up|TGFB3-up COL1A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|SERPINE1-down COMP-up|TGFB3-up COMP-up|SERPINE1-down FIGF-down|TGFB3-up FIGF-down|FZD5-down FLT1-down|ID1-down FLT1-down|SERPINE1-down FLT1-down|SOX2-up FLT1-down|TGFB3-up FLT1-down|FZD5-down ITGB8-up|FZD5-down JUN-down|FZD5-down PDGFRA-down|ID1-down IGF1-up|ID1-down JUN-down|ID1-down PDGFRA-down|ID1-down SPP1-up|ID1-down THBS1-down|ID1-down THBS2-up|SERPINE1-down IGF1-up|SOX2-up IGF1-up|TCF7L2-up IGF1-up|TGFB3-up IGF1-up|TGFB3-up ITGB8-up|SERPINE1-down JUN-down|SOX2-up JUN-down|TCF7L2-up JUN-down|TGFB3-up JUN-down|SERPINE1-down LAMA3-down|SOX2-up PDGFRA-down|TCF7L2-up PDGFRA-down|TGFB3-up PDGFRA-down|SERPINE1-down SPP1-up|SERPINE1-down THBS1-down|SERPINE1-down THBS2-up|SERPINE1-down TNC-up|SOX2-up SPP1-up|SOX2-up THBS1-down|SOX2-up TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	SERPINE1-down_5054 CAV2-down_858|CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 FZD5-down_7855|CCND2-up_894 SERPINE1-down_5054|SERPINE1-down_5054 COL1A1-up_1277|SOX2-up_6657 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|SERPINE1-down_5054 COL1A2-up_1278|SOX2-up_6657 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|SERPINE1-down_5054 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|SERPINE1-down_5054 FIGF-down_2277|TGFB3-up_7043 FIGF-down_2277|FZD5-down_7855 FLT1-down_2321|ID1-down_3397 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|SOX2-up_6657 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 JUN-down_3725|FZD5-down_7855 PDGFRA-down_5156|ID1-down_3397 IGF1-up_3479|ID1-down_3397 JUN-down_3725|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 SPP1-up_6696|ID1-down_3397 THBS1-down_7057|ID1-down_3397 THBS2-up_7058|SERPINE1-down_5054 IGF1-up_3479|SOX2-up_6657 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|TGFB3-up_7043 ITGB8-up_3696|SERPINE1-down_5054 JUN-down_3725|SOX2-up_6657 JUN-down_3725|TCF7L2-up_6934 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|SERPINE1-down_5054 LAMA3-down_3909|SOX2-up_6657 PDGFRA-down_5156|TCF7L2-up_6934 PDGFRA-down_5156|TGFB3-up_7043 PDGFRA-down_5156|SERPINE1-down_5054 SPP1-up_6696|SERPINE1-down_5054 THBS1-down_7057|SERPINE1-down_5054 THBS2-up_7058|SERPINE1-down_5054 TNC-up_3371|SOX2-up_6657 SPP1-up_6696|SOX2-up_6657 THBS1-down_7057|SOX2-up_6657 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04390	hsa04512	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up ITGB4-up|CCND1-up LAMA3-down|CCND1-up SPP1-up|CCND1-up THBS1-down|CCND1-up THBS2-up|CCND1-up TNC-up|CCND2-up COL1A2-up|CCND2-up THBS1-down|CCND2-up TNC-up|SERPINE1-down COL1A1-up|SOX2-up COL1A1-up|TCF7L2-up COL1A1-up|TGFB3-up COL1A1-up|SERPINE1-down COL1A2-up|SOX2-up COL1A2-up|TGFB3-up COL1A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|SERPINE1-down COMP-up|TGFB3-up COMP-up|FZD5-down ITGB8-up|ID1-down SPP1-up|ID1-down THBS1-down|ID1-down THBS2-up|TGFB3-up ITGB8-up|SERPINE1-down LAMA3-down|SERPINE1-down SPP1-up|SERPINE1-down THBS1-down|SERPINE1-down THBS2-up|SERPINE1-down TNC-up|SOX2-up SPP1-up|SOX2-up THBS1-down|SOX2-up TNC-up|TGFB3-up SPP1-up|TGFB3-up THBS1-down|TGFB3-up THBS2-up|TGFB3-up TNC-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 SPP1-up_6696|CCND1-up_595 THBS1-down_7057|CCND1-up_595 THBS2-up_7058|CCND1-up_595 TNC-up_3371|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 THBS1-down_7057|CCND2-up_894 TNC-up_3371|SERPINE1-down_5054 COL1A1-up_1277|SOX2-up_6657 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|SERPINE1-down_5054 COL1A2-up_1278|SOX2-up_6657 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|SERPINE1-down_5054 COMP-up_1311|TGFB3-up_7043 COMP-up_1311|FZD5-down_7855 ITGB8-up_3696|ID1-down_3397 SPP1-up_6696|ID1-down_3397 THBS1-down_7057|ID1-down_3397 THBS2-up_7058|TGFB3-up_7043 ITGB8-up_3696|SERPINE1-down_5054 LAMA3-down_3909|SERPINE1-down_5054 SPP1-up_6696|SERPINE1-down_5054 THBS1-down_7057|SERPINE1-down_5054 THBS2-up_7058|SERPINE1-down_5054 TNC-up_3371|SOX2-up_6657 SPP1-up_6696|SOX2-up_6657 THBS1-down_7057|SOX2-up_6657 TNC-up_3371|TGFB3-up_7043 SPP1-up_6696|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 THBS2-up_7058|TGFB3-up_7043 TNC-up_3371
hsa04390	hsa04514	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CCND1-up CD274-down|CCND1-up CDH2-up|CCND1-up CDH3-up|CCND1-up NCAM1-up|CCND1-up VCAM1-up|CCND2-up CDH2-up|CCND2-up NCAM1-up|FZD5-down CDH2-up|SERPINE1-down CDH2-up|SOX2-up CDH2-up|TCF7L2-up CDH2-up|TGFB3-up CDH2-up|SOX2-up CDH3-up|TCF7L2-up CLDN1-up|SERPINE1-down CLDN5-down|TCF7L2-up CLDN5-down|FZD5-down ITGB8-up|TGFB3-up ITGB8-up|SERPINE1-down NCAM1-up|SOX2-up NCAM1-up|TGFB3-up NCAM1-up|SERPINE1-down SELL-down|SERPINE1-down VCAM1-up|TGFB3-up VCAM1-up	CCND1-up_595 CD274-down_29126|CCND1-up_595 CDH2-up_1000|CCND1-up_595 CDH3-up_1001|CCND1-up_595 NCAM1-up_4684|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CDH2-up_1000|CCND2-up_894 NCAM1-up_4684|FZD5-down_7855 CDH2-up_1000|SERPINE1-down_5054 CDH2-up_1000|SOX2-up_6657 CDH2-up_1000|TCF7L2-up_6934 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|SOX2-up_6657 CDH3-up_1001|TCF7L2-up_6934 CLDN1-up_9076|SERPINE1-down_5054 CLDN5-down_7122|TCF7L2-up_6934 CLDN5-down_7122|FZD5-down_7855 ITGB8-up_3696|TGFB3-up_7043 ITGB8-up_3696|SERPINE1-down_5054 NCAM1-up_4684|SOX2-up_6657 NCAM1-up_4684|TGFB3-up_7043 NCAM1-up_4684|SERPINE1-down_5054 SELL-down_6402|SERPINE1-down_5054 VCAM1-up_7412|TGFB3-up_7043 VCAM1-up_7412
hsa04390	hsa04668	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.002	CCND1-up JUN-down|CCND1-up MAP3K8-down|CCND1-up SOCS3-down|CCND1-up VCAM1-up|CCND2-up CXCL2-down|CCND2-up JUN-down|CCND2-up MAP3K8-down|CCND2-up SOCS3-down|FZD5-down JUN-down|FZD5-down MAP3K8-down|ID1-down JUN-down|SERPINE1-down JUN-down|SOX2-up JUN-down|TCF7L2-up JUN-down|TGFB3-up JUN-down|SERPINE1-down MAP3K8-down|SERPINE1-down SOCS3-down|SERPINE1-down VCAM1-up|SOX2-up SOCS3-down|TGFB3-up VCAM1-up	CCND1-up_595 JUN-down_3725|CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 SOCS3-down_9021|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL2-down_2920|CCND2-up_894 JUN-down_3725|CCND2-up_894 MAP3K8-down_1326|CCND2-up_894 SOCS3-down_9021|FZD5-down_7855 JUN-down_3725|FZD5-down_7855 MAP3K8-down_1326|ID1-down_3397 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|SOX2-up_6657 JUN-down_3725|TCF7L2-up_6934 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|SERPINE1-down_5054 MAP3K8-down_1326|SERPINE1-down_5054 SOCS3-down_9021|SERPINE1-down_5054 VCAM1-up_7412|SOX2-up_6657 SOCS3-down_9021|TGFB3-up_7043 VCAM1-up_7412
hsa04390	hsa04670	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|CCND2-up CXCL12-up|CCND2-up MMP2-up|TCF7L2-up CLDN1-up|SERPINE1-down CLDN5-down|TCF7L2-up CLDN5-down|ID1-down CXCL12-up|SERPINE1-down CXCL12-up|SOX2-up CXCL12-up|TGFB3-up CXCL12-up|ID1-down MMP2-up|ID1-down THY1-up|SERPINE1-down MMP2-up|SOX2-up MMP2-up|TCF7L2-up MMP2-up|TGFB3-up MMP2-up|SERPINE1-down THY1-up|SERPINE1-down VCAM1-up|SOX2-up THY1-up|TGFB3-up THY1-up|TGFB3-up VCAM1-up	CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP2-up_4313|TCF7L2-up_6934 CLDN1-up_9076|SERPINE1-down_5054 CLDN5-down_7122|TCF7L2-up_6934 CLDN5-down_7122|ID1-down_3397 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|SOX2-up_6657 CXCL12-up_6387|TGFB3-up_7043 CXCL12-up_6387|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THY1-up_7070|SERPINE1-down_5054 MMP2-up_4313|SOX2-up_6657 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|SERPINE1-down_5054 THY1-up_7070|SERPINE1-down_5054 VCAM1-up_7412|SOX2-up_6657 THY1-up_7070|TGFB3-up_7043 THY1-up_7070|TGFB3-up_7043 VCAM1-up_7412
hsa04390	hsa04915	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.002	CCND1-up HBEGF-down|CCND1-up HSPA1A-down|CCND1-up JUN-down|CCND1-up MMP2-up|CCND2-up HBEGF-down|CCND2-up JUN-down|CCND2-up MMP2-up|FZD5-down GABBR2-up|FZD5-down JUN-down|SERPINE1-down HBEGF-down|TGFB3-up HBEGF-down|ID1-down JUN-down|ID1-down MMP2-up|SERPINE1-down JUN-down|SOX2-up JUN-down|TCF7L2-up JUN-down|TGFB3-up JUN-down|SERPINE1-down MMP2-up|SOX2-up MMP2-up|TCF7L2-up MMP2-up|TGFB3-up MMP2-up	CCND1-up_595 HBEGF-down_1839|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP2-up_4313|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|FZD5-down_7855 GABBR2-up_9568|FZD5-down_7855 JUN-down_3725|SERPINE1-down_5054 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|SERPINE1-down_5054 JUN-down_3725|SOX2-up_6657 JUN-down_3725|TCF7L2-up_6934 JUN-down_3725|TGFB3-up_7043 JUN-down_3725|SERPINE1-down_5054 MMP2-up_4313|SOX2-up_6657 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313
hsa04390	hsa04933	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.007	CCND1-up FZD5-down|CCND1-up ID1-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up JUN-down|CCND2-up MMP2-up|CCND2-up TGFB3-up|SOX2-up COL1A1-up|TCF7L2-up COL1A1-up|SOX2-up COL1A2-up|SOX2-up F3-down|FZD5-down JUN-down|ID1-down JUN-down|ID1-down MMP2-up|ID1-down SERPINE1-down|ID1-down TGFB3-up|SOX2-up JUN-down|TCF7L2-up JUN-down|SOX2-up MMP2-up|TCF7L2-up MMP2-up|TCF7L2-up TGFB3-up	CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|CCND2-up_894 TGFB3-up_7043|SOX2-up_6657 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|SOX2-up_6657 COL1A2-up_1278|SOX2-up_6657 F3-down_2152|FZD5-down_7855 JUN-down_3725|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|ID1-down_3397 SERPINE1-down_5054|ID1-down_3397 TGFB3-up_7043|SOX2-up_6657 JUN-down_3725|TCF7L2-up_6934 JUN-down_3725|SOX2-up_6657 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|TCF7L2-up_6934 TGFB3-up_7043
hsa04390	hsa04974	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CCND1-up COL18A1-up|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up MME-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up MME-down|TGFB3-up COL10A1-up|TGFB3-up COL14A1-up|SERPINE1-down COL18A1-up|TGFB3-up COL18A1-up|SERPINE1-down COL1A1-up|SOX2-up COL1A1-up|TCF7L2-up COL1A1-up|TGFB3-up COL1A1-up|SERPINE1-down COL1A2-up|SOX2-up COL1A2-up|TGFB3-up COL1A2-up|SERPINE1-down COL3A1-up|TGFB3-up COL3A1-up|SERPINE1-down COL5A1-up|TGFB3-up COL5A1-up|SERPINE1-down COL5A2-up|TGFB3-up COL5A2-up|TGFB3-up COL6A1-up|TGFB3-up COL6A3-up|SERPINE1-down COL7A1-up|SOX2-up KCNN4-up|SERPINE1-down MME-down|SERPINE1-down PRSS1-up	CCND1-up_595 COL18A1-up_80781|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 MME-down_4311|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 MME-down_4311|TGFB3-up_7043 COL10A1-up_1300|TGFB3-up_7043 COL14A1-up_7373|SERPINE1-down_5054 COL18A1-up_80781|TGFB3-up_7043 COL18A1-up_80781|SERPINE1-down_5054 COL1A1-up_1277|SOX2-up_6657 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|TGFB3-up_7043 COL1A1-up_1277|SERPINE1-down_5054 COL1A2-up_1278|SOX2-up_6657 COL1A2-up_1278|TGFB3-up_7043 COL1A2-up_1278|SERPINE1-down_5054 COL3A1-up_1281|TGFB3-up_7043 COL3A1-up_1281|SERPINE1-down_5054 COL5A1-up_1289|TGFB3-up_7043 COL5A1-up_1289|SERPINE1-down_5054 COL5A2-up_1290|TGFB3-up_7043 COL5A2-up_1290|TGFB3-up_7043 COL6A1-up_1291|TGFB3-up_7043 COL6A3-up_1293|SERPINE1-down_5054 COL7A1-up_1294|SOX2-up_6657 KCNN4-up_3783|SERPINE1-down_5054 MME-down_4311|SERPINE1-down_5054 PRSS1-up_5644
hsa04390	hsa05145	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.046	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up LDLR-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|ID1-down TGFB3-up|SERPINE1-down JAK1-down|SERPINE1-down LAMA3-down|SERPINE1-down LDLR-down|TCF7L2-up LDLR-down|SERPINE1-down TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 LDLR-down_3949|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|ID1-down_3397 TGFB3-up_7043|SERPINE1-down_5054 JAK1-down_3716|SERPINE1-down_5054 LAMA3-down_3909|SERPINE1-down_5054 LDLR-down_3949|TCF7L2-up_6934 LDLR-down_3949|SERPINE1-down_5054 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04390	hsa05146	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.001	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up LAMA3-down|CCND1-up TGFB3-up|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up TGFB3-up|SERPINE1-down COL1A1-up|SOX2-up COL1A1-up|TCF7L2-up COL1A1-up|SERPINE1-down COL1A2-up|SOX2-up COL1A2-up|SERPINE1-down COL3A1-up|ID1-down TGFB3-up|SERPINE1-down LAMA3-down|SERPINE1-down SERPINB3-up|SERPINE1-down TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 TGFB3-up_7043|SERPINE1-down_5054 COL1A1-up_1277|SOX2-up_6657 COL1A1-up_1277|TCF7L2-up_6934 COL1A1-up_1277|SERPINE1-down_5054 COL1A2-up_1278|SOX2-up_6657 COL1A2-up_1278|SERPINE1-down_5054 COL3A1-up_1281|ID1-down_3397 TGFB3-up_7043|SERPINE1-down_5054 LAMA3-down_3909|SERPINE1-down_5054 SERPINB3-up_6317|SERPINE1-down_5054 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04390	hsa05200	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.005	CCND1-up ID1-down|CCND1-up SERPINE1-down|CCND2-up CXCL12-up|CCND2-up HHIP-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up PDGFRA-down|CCND2-up TCF7L2-up|CCND2-up TGFB3-up|CCND2-up ZBTB16-down|ID1-down CXCL12-up|SERPINE1-down CXCL12-up|SOX2-up CXCL12-up|SERPINE1-down EDNRB-down|SERPINE1-down FIGF-down|ID1-down IGF1-up|ID1-down JUN-down|ID1-down MMP1-up|ID1-down MMP2-up|ID1-down PDGFRA-down|ID1-down TGFB3-up|SERPINE1-down IGF1-up|SOX2-up IGF1-up|SERPINE1-down JAK1-down|SERPINE1-down JUN-down|SOX2-up JUN-down|SERPINE1-down LAMA3-down|SERPINE1-down MMP1-up|SERPINE1-down MMP2-up|SOX2-up MMP2-up|SOX2-up PDGFRA-down|SERPINE1-down TGFB3-up|SOX2-up ZBTB16-down	CCND1-up_595 ID1-down_3397|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 HHIP-down_64399|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 TCF7L2-up_6934|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 ZBTB16-down_7704|ID1-down_3397 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|SOX2-up_6657 CXCL12-up_6387|SERPINE1-down_5054 EDNRB-down_1910|SERPINE1-down_5054 FIGF-down_2277|ID1-down_3397 IGF1-up_3479|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP1-up_4312|ID1-down_3397 MMP2-up_4313|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 TGFB3-up_7043|SERPINE1-down_5054 IGF1-up_3479|SOX2-up_6657 IGF1-up_3479|SERPINE1-down_5054 JAK1-down_3716|SERPINE1-down_5054 JUN-down_3725|SOX2-up_6657 JUN-down_3725|SERPINE1-down_5054 LAMA3-down_3909|SERPINE1-down_5054 MMP1-up_4312|SERPINE1-down_5054 MMP2-up_4313|SOX2-up_6657 MMP2-up_4313|SOX2-up_6657 PDGFRA-down_5156|SERPINE1-down_5054 TGFB3-up_7043|SOX2-up_6657 ZBTB16-down_7704
hsa04390	hsa05202	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up FZD5-down|CCND2-up SERPINE1-down|FZD5-down FLT1-down|ID1-down FLT1-down|SERPINE1-down FLT1-down|SOX2-up FLT1-down|TGFB3-up FLT1-down|FZD5-down PROM1-up|ID1-down IGF1-up|ID1-down PLAU-up|SERPINE1-down IGF1-up|SOX2-up IGF1-up|TCF7L2-up IGF1-up|TGFB3-up IGF1-up|SERPINE1-down PLAU-up|TGFB3-up PLAU-up|SERPINE1-down PROM1-up|SOX2-up PROM1-up|SOX2-up SIX1-up|TGFB3-up SIX1-up|SOX2-up SIX4-up|SOX2-up ZBTB16-down	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 FZD5-down_7855|CCND2-up_894 SERPINE1-down_5054|FZD5-down_7855 FLT1-down_2321|ID1-down_3397 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|SOX2-up_6657 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|FZD5-down_7855 PROM1-up_8842|ID1-down_3397 IGF1-up_3479|ID1-down_3397 PLAU-up_5328|SERPINE1-down_5054 IGF1-up_3479|SOX2-up_6657 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|SERPINE1-down_5054 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|SERPINE1-down_5054 PROM1-up_8842|SOX2-up_6657 PROM1-up_8842|SOX2-up_6657 SIX1-up_6495|TGFB3-up_7043 SIX1-up_6495|SOX2-up_6657 SIX4-up_51804|SOX2-up_6657 ZBTB16-down_7704
hsa04390	hsa05205	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	TCF7L2-up ANK2-up|SERPINE1-down CAV2-down|CCND1-up ID1-down|CCND1-up SERPINE1-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|CCND2-up THBS1-down|SERPINE1-down HBEGF-down|TGFB3-up HBEGF-down|ID1-down IGF1-up|ID1-down MMP2-up|ID1-down PLAU-up|ID1-down THBS1-down|SERPINE1-down IGF1-up|SOX2-up IGF1-up|TCF7L2-up IGF1-up|TGFB3-up IGF1-up|SERPINE1-down MMP2-up|SOX2-up MMP2-up|TCF7L2-up MMP2-up|TGFB3-up MMP2-up|SERPINE1-down PLAU-up|TGFB3-up PLAU-up|SERPINE1-down THBS1-down|SOX2-up THBS1-down|TGFB3-up THBS1-down	TCF7L2-up_6934 ANK2-up_287|SERPINE1-down_5054 CAV2-down_858|CCND1-up_595 ID1-down_3397|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|CCND2-up_894 THBS1-down_7057|SERPINE1-down_5054 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|ID1-down_3397 IGF1-up_3479|ID1-down_3397 MMP2-up_4313|ID1-down_3397 PLAU-up_5328|ID1-down_3397 THBS1-down_7057|SERPINE1-down_5054 IGF1-up_3479|SOX2-up_6657 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|SERPINE1-down_5054 MMP2-up_4313|SOX2-up_6657 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|SERPINE1-down_5054 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|SERPINE1-down_5054 THBS1-down_7057|SOX2-up_6657 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057
hsa04390	hsa05206	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CCND1-up FZD5-down|CCND1-up ID1-down|CCND1-up SERPINE1-down|CCND2-up FZD5-down|CCND2-up SERPINE1-down|FZD5-down PDGFRA-down|SERPINE1-down HMOX1-down|SOX2-up HMOX1-down|ID1-down PDGFRA-down|ID1-down PLAU-up|ID1-down THBS1-down|SERPINE1-down IRS2-down|TCF7L2-up IRS2-down|SERPINE1-down MCL1-down|SOX2-up MCL1-down|SERPINE1-down MMP16-up|SOX2-up PDGFRA-down|TCF7L2-up PDGFRA-down|TGFB3-up PDGFRA-down|SERPINE1-down PLAU-up|TGFB3-up PLAU-up|SERPINE1-down SERPINB5-up|SERPINE1-down THBS1-down|SERPINE1-down TNC-up|SERPINE1-down TP63-up|SOX2-up SOX4-up|SOX2-up THBS1-down|SOX2-up TNC-up|SOX2-up TP63-up|TCF7L2-up TP63-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 FZD5-down_7855|CCND2-up_894 SERPINE1-down_5054|FZD5-down_7855 PDGFRA-down_5156|SERPINE1-down_5054 HMOX1-down_3162|SOX2-up_6657 HMOX1-down_3162|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 PLAU-up_5328|ID1-down_3397 THBS1-down_7057|SERPINE1-down_5054 IRS2-down_8660|TCF7L2-up_6934 IRS2-down_8660|SERPINE1-down_5054 MCL1-down_4170|SOX2-up_6657 MCL1-down_4170|SERPINE1-down_5054 MMP16-up_4325|SOX2-up_6657 PDGFRA-down_5156|TCF7L2-up_6934 PDGFRA-down_5156|TGFB3-up_7043 PDGFRA-down_5156|SERPINE1-down_5054 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|SERPINE1-down_5054 SERPINB5-up_5268|SERPINE1-down_5054 THBS1-down_7057|SERPINE1-down_5054 TNC-up_3371|SERPINE1-down_5054 TP63-up_8626|SOX2-up_6657 SOX4-up_6659|SOX2-up_6657 THBS1-down_7057|SOX2-up_6657 TNC-up_3371|SOX2-up_6657 TP63-up_8626|TCF7L2-up_6934 TP63-up_8626|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa04390	hsa05219	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCND1-up FZD5-down|CCND1-up ID1-down|CCND1-up SERPINE1-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up THBS1-down|SERPINE1-down HBEGF-down|TGFB3-up HBEGF-down|ID1-down MMP1-up|ID1-down MMP2-up|ID1-down THBS1-down|SERPINE1-down MMP1-up|TGFB3-up MMP1-up|SERPINE1-down MMP2-up|SOX2-up MMP2-up|TCF7L2-up MMP2-up|TGFB3-up MMP2-up|SERPINE1-down THBS1-down|SOX2-up THBS1-down|TGFB3-up THBS1-down	CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 THBS1-down_7057|SERPINE1-down_5054 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|ID1-down_3397 MMP1-up_4312|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THBS1-down_7057|SERPINE1-down_5054 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|SERPINE1-down_5054 MMP2-up_4313|SOX2-up_6657 MMP2-up_4313|TCF7L2-up_6934 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|SERPINE1-down_5054 THBS1-down_7057|SOX2-up_6657 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057
hsa04390	hsa05323	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up FLT1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|SERPINE1-down CTSK-up|ID1-down CXCL12-up|SERPINE1-down CXCL12-up|SOX2-up CXCL12-up|FZD5-down FLT1-down|ID1-down FLT1-down|SERPINE1-down FLT1-down|SOX2-up FLT1-down|FZD5-down JUN-down|ID1-down JUN-down|ID1-down MMP1-up|ID1-down TGFB3-up|SERPINE1-down JUN-down|SOX2-up JUN-down|TCF7L2-up JUN-down|SERPINE1-down MMP1-up|SERPINE1-down TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|SERPINE1-down_5054 CTSK-up_1513|ID1-down_3397 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|SOX2-up_6657 CXCL12-up_6387|FZD5-down_7855 FLT1-down_2321|ID1-down_3397 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|SOX2-up_6657 FLT1-down_2321|FZD5-down_7855 JUN-down_3725|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP1-up_4312|ID1-down_3397 TGFB3-up_7043|SERPINE1-down_5054 JUN-down_3725|SOX2-up_6657 JUN-down_3725|TCF7L2-up_6934 JUN-down_3725|SERPINE1-down_5054 MMP1-up_4312|SERPINE1-down_5054 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04390	hsa05410	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.004	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|FZD5-down ITGB8-up|ID1-down IGF1-up|ID1-down TGFB3-up|SERPINE1-down IGF1-up|SOX2-up IGF1-up|TCF7L2-up IGF1-up|SERPINE1-down TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|FZD5-down_7855 ITGB8-up_3696|ID1-down_3397 IGF1-up_3479|ID1-down_3397 TGFB3-up_7043|SERPINE1-down_5054 IGF1-up_3479|SOX2-up_6657 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|SERPINE1-down_5054 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04390	hsa05412	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.001	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|FZD5-down CDH2-up|SERPINE1-down CDH2-up|SOX2-up CDH2-up|TGFB3-up CDH2-up|TGFB3-up DES-up|FZD5-down ITGB8-up|FZD5-down TCF7L2-up|TGFB3-up ITGB8-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|FZD5-down_7855 CDH2-up_1000|SERPINE1-down_5054 CDH2-up_1000|SOX2-up_6657 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 TCF7L2-up_6934|TGFB3-up_7043 ITGB8-up_3696
hsa04390	hsa05414	Hippo signaling pathway - Homo sapiens (human)	FZD5,ID1,SERPINE1,CCND1,CCND2,FRMD6,SOX2,TCF7L2,TGFB3	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.029	SERPINE1-down ADRB1-down|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up TGFB3-up|FZD5-down ITGB8-up|ID1-down IGF1-up|ID1-down TGFB3-up|SERPINE1-down IGF1-up|SOX2-up IGF1-up|TCF7L2-up IGF1-up|SERPINE1-down TGFB3-up|TCF7L2-up TGFB3-up	SERPINE1-down_5054 ADRB1-down_153|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 TGFB3-up_7043|FZD5-down_7855 ITGB8-up_3696|ID1-down_3397 IGF1-up_3479|ID1-down_3397 TGFB3-up_7043|SERPINE1-down_5054 IGF1-up_3479|SOX2-up_6657 IGF1-up_3479|TCF7L2-up_6934 IGF1-up_3479|SERPINE1-down_5054 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa04510	hsa04512	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	0.005	CAV2-down ITGB4-up|CAV2-down ITGB8-up|CAV2-down LAMA3-down|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up ITGB4-up|CCND1-up SPP1-up|CCND1-up THBS2-up|CCND1-up TNC-up|CCND2-up COL1A2-up|CCND2-up TNC-up|COL1A1-up FIGF-down|COL1A1-up FLT1-down|COL1A1-up JUN-down|COL1A1-up PDGFRA-down|COL1A2-up FIGF-down|COL1A2-up FLT1-down|COL1A2-up JUN-down|COL1A2-up PDGFRA-down|COL6A1-up JUN-down|COL6A1-up PDGFRA-down|COL6A3-up JUN-down|COL6A3-up PDGFRA-down|COMP-up JUN-down|FIGF-down SPP1-up|FIGF-down THBS1-down|FIGF-down THBS2-up|FIGF-down TNC-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TNC-up|FLT1-down ITGB4-up|FLT1-down SPP1-up|FLT1-down THBS1-down|FLT1-down THBS2-up|FLT1-down TNC-up|IGF1-up SPP1-up|IGF1-up THBS2-up|IGF1-up TNC-up|ITGB4-up JUN-down|ITGB4-up PDGFRA-down|JUN-down LAMA3-down|JUN-down SPP1-up|JUN-down THBS1-down|JUN-down THBS2-up|JUN-down TNC-up|PDGFRA-down SPP1-up|PDGFRA-down THBS1-down|PDGFRA-down TNC-up	CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CAV2-down_858 LAMA3-down_3909|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 SPP1-up_6696|CCND1-up_595 THBS2-up_7058|CCND1-up_595 TNC-up_3371|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 TNC-up_3371|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 PDGFRA-down_5156|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 PDGFRA-down_5156|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 PDGFRA-down_5156|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 PDGFRA-down_5156|COMP-up_1311 JUN-down_3725|FIGF-down_2277 SPP1-up_6696|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 THBS2-up_7058|FIGF-down_2277 TNC-up_3371|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TNC-up_3371|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 SPP1-up_6696|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 THBS2-up_7058|FLT1-down_2321 TNC-up_3371|IGF1-up_3479 SPP1-up_6696|IGF1-up_3479 THBS2-up_7058|IGF1-up_3479 TNC-up_3371|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 PDGFRA-down_5156|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SPP1-up_6696|JUN-down_3725 THBS1-down_7057|JUN-down_3725 THBS2-up_7058|JUN-down_3725 TNC-up_3371|PDGFRA-down_5156 SPP1-up_6696|PDGFRA-down_5156 THBS1-down_7057|PDGFRA-down_5156 TNC-up_3371
hsa04510	hsa04514	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	CAV2-down CDH2-up|CAV2-down ITGB8-up|CCND1-up CD274-down|CCND1-up CDH2-up|CCND1-up CDH3-up|CCND1-up NCAM1-up|CCND1-up VCAM1-up|CCND2-up CDH2-up|CCND2-up NCAM1-up|IGF1-up CD274-down|PDGFRA-down CD274-down|COL1A1-up CDH2-up|COL1A2-up CDH2-up|COMP-up CDH2-up|FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|ITGB4-up CDH2-up|JUN-down CDH2-up|PDGFRA-down CDH2-up|SPP1-up CDH2-up|THBS1-down CDH2-up|THBS2-up CDH2-up|TNC-up CDH2-up|LAMA3-down CDH3-up|TNC-up CDH3-up|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|JUN-down CLDN5-down|THBS1-down CLDN5-down|COL1A1-up ITGB8-up|COL1A1-up VCAM1-up|COL1A2-up ITGB8-up|COL1A2-up NCAM1-up|COL6A1-up ITGB8-up|COL6A3-up ITGB8-up|COMP-up ITGB8-up|FIGF-down VCAM1-up|FLNC-up ITGB8-up|FLNC-up VCAM1-up|FLT1-down NCAM1-up|FLT1-down SELL-down|FLT1-down VCAM1-up|IGF1-up NCAM1-up|IGF1-up SELL-down|IGF1-up VCAM1-up|ITGA10-down ITGB8-up|ITGB4-up ITGB8-up|ITGB4-up NCAM1-up|ITGB4-up VCAM1-up|ITGB8-up LAMA3-down|ITGB8-up THBS1-down|JUN-down NCAM1-up|JUN-down SELL-down|JUN-down VCAM1-up|LAMA3-down VCAM1-up|PDGFRA-down NCAM1-up|SPP1-up NCAM1-up|THBS1-down NCAM1-up|TNC-up NCAM1-up|TNC-up NFASC-up|PDGFRA-down VCAM1-up|SPP1-up VCAM1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CAV2-down_858 CDH2-up_1000|CAV2-down_858 ITGB8-up_3696|CCND1-up_595 CD274-down_29126|CCND1-up_595 CDH2-up_1000|CCND1-up_595 CDH3-up_1001|CCND1-up_595 NCAM1-up_4684|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CDH2-up_1000|CCND2-up_894 NCAM1-up_4684|IGF1-up_3479 CD274-down_29126|PDGFRA-down_5156 CD274-down_29126|COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COMP-up_1311 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|ITGB4-up_3691 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|SPP1-up_6696 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS2-up_7058 CDH2-up_1000|TNC-up_3371 CDH2-up_1000|LAMA3-down_3909 CDH3-up_1001|TNC-up_3371 CDH3-up_1001|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|JUN-down_3725 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 NCAM1-up_4684|COL6A1-up_1291 ITGB8-up_3696|COL6A3-up_1293 ITGB8-up_3696|COMP-up_1311 ITGB8-up_3696|FIGF-down_2277 VCAM1-up_7412|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 VCAM1-up_7412|FLT1-down_2321 NCAM1-up_4684|FLT1-down_2321 SELL-down_6402|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 NCAM1-up_4684|IGF1-up_3479 SELL-down_6402|IGF1-up_3479 VCAM1-up_7412|ITGA10-down_8515 ITGB8-up_3696|ITGB4-up_3691 ITGB8-up_3696|ITGB4-up_3691 NCAM1-up_4684|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057|JUN-down_3725 NCAM1-up_4684|JUN-down_3725 SELL-down_6402|JUN-down_3725 VCAM1-up_7412|LAMA3-down_3909 VCAM1-up_7412|PDGFRA-down_5156 NCAM1-up_4684|SPP1-up_6696 NCAM1-up_4684|THBS1-down_7057 NCAM1-up_4684|TNC-up_3371 NCAM1-up_4684|TNC-up_3371 NFASC-up_23114|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04510	hsa04550	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0	CCND1-up FZD5-down|CCND1-up ID1-down|CCND1-up IGF1-up|CCND1-up JAK1-down|CCND1-up LIFR-down|CCND1-up SOX2-up|CCND2-up FZD5-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up SOX2-up|COL1A1-up IGF1-up|COL1A1-up SOX2-up|COL1A2-up IGF1-up|COL1A2-up JAK1-down|COL1A2-up SOX2-up|COMP-up IGF1-up|FIGF-down IGF1-up|FLT1-down FZD5-down|FLT1-down ID1-down|FLT1-down IGF1-up|FLT1-down JAK1-down|FLT1-down SOX2-up|ITGB8-up FZD5-down|JUN-down FZD5-down|PDGFRA-down FZD5-down|JUN-down ID1-down|PDGFRA-down ID1-down|SPP1-up ID1-down|THBS1-down ID1-down|THBS2-up ID1-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|JUN-down JAK1-down|PDGFRA-down JAK1-down|JUN-down LIFR-down|JUN-down SOX2-up|SPP1-up LIFR-down|PDGFRA-down SOX2-up|SPP1-up SOX2-up|THBS1-down SOX2-up|TNC-up SOX2-up	CCND1-up_595 FZD5-down_7855|CCND1-up_595 ID1-down_3397|CCND1-up_595 IGF1-up_3479|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LIFR-down_3977|CCND1-up_595 SOX2-up_6657|CCND2-up_894 FZD5-down_7855|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOX2-up_6657|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 SOX2-up_6657|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 SOX2-up_6657|COMP-up_1311 IGF1-up_3479|FIGF-down_2277 IGF1-up_3479|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 ID1-down_3397|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 SOX2-up_6657|ITGB8-up_3696 FZD5-down_7855|JUN-down_3725 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|JUN-down_3725 ID1-down_3397|PDGFRA-down_5156 ID1-down_3397|SPP1-up_6696 ID1-down_3397|THBS1-down_7057 ID1-down_3397|THBS2-up_7058 ID1-down_3397|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|JUN-down_3725 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|JUN-down_3725 LIFR-down_3977|JUN-down_3725 SOX2-up_6657|SPP1-up_6696 LIFR-down_3977|PDGFRA-down_5156 SOX2-up_6657|SPP1-up_6696 SOX2-up_6657|THBS1-down_7057 SOX2-up_6657|TNC-up_3371 SOX2-up_6657
hsa04510	hsa04610	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0	CAV2-down F3-down|CAV2-down SERPINE1-down|CCND1-up CFH-up|CCND1-up PLAU-up|CCND1-up SERPINE1-down|CCND2-up PLAU-up|CCND2-up SERPINE1-down|FLT1-down CFH-up|IGF1-up CFH-up|JUN-down CFH-up|PDGFRA-down CFH-up|SPP1-up CFH-up|THBS1-down CFH-up|COL1A1-up PLAU-up|COL1A1-up SERPINE1-down|COL1A2-up PLAU-up|COL1A2-up SERPINE1-down|COL6A3-up PLAU-up|COMP-up SERPINE1-down|FLNC-up F3-down|FLT1-down F3-down|IGF1-up F3-down|JUN-down F3-down|PDGFRA-down F3-down|THBS1-down F3-down|THBS2-up F3-down|TNC-up F3-down|FIGF-down PLAU-up|FIGF-down SERPINE1-down|FLNC-up TFPI-down|FLT1-down PLAU-up|FLT1-down SERPINE1-down|FLT1-down TFPI-down|IGF1-up SERPINE1-down|ITGB4-up PLAU-up|JUN-down PLAU-up|JUN-down SERPINE1-down|JUN-down TFPI-down|LAMA3-down PLAU-up|LAMA3-down SERPINE1-down|PDGFRA-down PLAU-up|SPP1-up PLAU-up|THBS1-down PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up|SPP1-up SERPINE1-down|THBS1-down SERPINE1-down|THBS2-up SERPINE1-down|TNC-up SERPINE1-down|SPP1-up TFPI-down|THBS1-down TFPI-down|THBS2-up TFPI-down|TNC-up TFPI-down	CAV2-down_858 F3-down_2152|CAV2-down_858 SERPINE1-down_5054|CCND1-up_595 CFH-up_3075|CCND1-up_595 PLAU-up_5328|CCND1-up_595 SERPINE1-down_5054|CCND2-up_894 PLAU-up_5328|CCND2-up_894 SERPINE1-down_5054|FLT1-down_2321 CFH-up_3075|IGF1-up_3479 CFH-up_3075|JUN-down_3725 CFH-up_3075|PDGFRA-down_5156 CFH-up_3075|SPP1-up_6696 CFH-up_3075|THBS1-down_7057 CFH-up_3075|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SERPINE1-down_5054|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 SERPINE1-down_5054|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 SERPINE1-down_5054|FLNC-up_2318 F3-down_2152|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|JUN-down_3725 F3-down_2152|PDGFRA-down_5156 F3-down_2152|THBS1-down_7057 F3-down_2152|THBS2-up_7058 F3-down_2152|TNC-up_3371 F3-down_2152|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 SERPINE1-down_5054|FLNC-up_2318 TFPI-down_7035|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TFPI-down_7035|IGF1-up_3479 SERPINE1-down_5054|ITGB4-up_3691 PLAU-up_5328|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINE1-down_5054|JUN-down_3725 TFPI-down_7035|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 SERPINE1-down_5054|PDGFRA-down_5156 PLAU-up_5328|SPP1-up_6696 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328|SPP1-up_6696 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS2-up_7058 SERPINE1-down_5054|TNC-up_3371 SERPINE1-down_5054|SPP1-up_6696 TFPI-down_7035|THBS1-down_7057 TFPI-down_7035|THBS2-up_7058 TFPI-down_7035|TNC-up_3371 TFPI-down_7035
hsa04510	hsa04668	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.001	CAV2-down JUN-down|CCND1-up MAP3K8-down|CCND1-up SOCS3-down|CCND1-up VCAM1-up|CCND2-up CXCL2-down|CCND2-up MAP3K8-down|CCND2-up SOCS3-down|COL1A1-up CXCL2-down|COL1A1-up SOCS3-down|COL1A1-up VCAM1-up|IGF1-up CXCL2-down|SPP1-up CXCL2-down|FIGF-down JUN-down|FIGF-down VCAM1-up|FLNC-up VCAM1-up|FLT1-down JUN-down|FLT1-down SOCS3-down|FLT1-down VCAM1-up|IGF1-up IL18R1-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|ITGB4-up VCAM1-up|LAMA3-down VCAM1-up|PDGFRA-down MAP3K8-down|PDGFRA-down SOCS3-down|PDGFRA-down VCAM1-up|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down|SPP1-up VCAM1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CAV2-down_858 JUN-down_3725|CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 SOCS3-down_9021|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL2-down_2920|CCND2-up_894 MAP3K8-down_1326|CCND2-up_894 SOCS3-down_9021|COL1A1-up_1277 CXCL2-down_2920|COL1A1-up_1277 SOCS3-down_9021|COL1A1-up_1277 VCAM1-up_7412|IGF1-up_3479 CXCL2-down_2920|SPP1-up_6696 CXCL2-down_2920|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 VCAM1-up_7412|FLNC-up_2318 VCAM1-up_7412|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|ITGB4-up_3691 VCAM1-up_7412|LAMA3-down_3909 VCAM1-up_7412|PDGFRA-down_5156 MAP3K8-down_1326|PDGFRA-down_5156 SOCS3-down_9021|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04510	hsa04670	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CAV2-down MMP2-up|CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|CCND2-up CXCL12-up|CCND2-up MMP2-up|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|JUN-down CLDN5-down|THBS1-down CLDN5-down|COL1A1-up CXCL12-up|COL1A1-up MMP2-up|COL1A1-up THY1-up|COL1A1-up VCAM1-up|COL1A2-up CXCL12-up|COL1A2-up MMP2-up|COL6A1-up MMP2-up|COL6A3-up MMP2-up|COMP-up CXCL12-up|COMP-up MMP2-up|FIGF-down CXCL12-up|FLT1-down CXCL12-up|IGF1-up CXCL12-up|JUN-down CXCL12-up|PDGFRA-down CXCL12-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|FIGF-down MMP2-up|FIGF-down VCAM1-up|FLNC-up VCAM1-up|FLT1-down MMP2-up|FLT1-down VCAM1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up|ITGB4-up MMP2-up|ITGB4-up THY1-up|ITGB4-up VCAM1-up|JUN-down MMP2-up|JUN-down THY1-up|JUN-down VCAM1-up|LAMA3-down MMP2-up|LAMA3-down VCAM1-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|PDGFRA-down VCAM1-up|SPP1-up THY1-up|SPP1-up VCAM1-up|THBS1-down THY1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CAV2-down_858 MMP2-up_4313|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP2-up_4313|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|JUN-down_3725 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 THY1-up_7070|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 MMP2-up_4313|FIGF-down_2277 CXCL12-up_6387|FLT1-down_2321 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|JUN-down_3725 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 VCAM1-up_7412|FLNC-up_2318 VCAM1-up_7412|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 THY1-up_7070|ITGB4-up_3691 VCAM1-up_7412|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THY1-up_7070|JUN-down_3725 VCAM1-up_7412|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 THY1-up_7070|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 THY1-up_7070|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04510	hsa04915	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	CAV2-down JUN-down|CAV2-down MMP2-up|CCND1-up HBEGF-down|CCND1-up HSPA1A-down|CCND1-up MMP2-up|CCND2-up HBEGF-down|CCND2-up MMP2-up|COL1A1-up HSPA1A-down|COL1A1-up MMP2-up|COL1A2-up MMP2-up|COL6A1-up MMP2-up|COL6A3-up MMP2-up|COMP-up MMP2-up|FIGF-down HBEGF-down|FIGF-down JUN-down|FIGF-down MMP2-up|FLT1-down HBEGF-down|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JUN-down|FLT1-down MMP2-up|SPP1-up GABBR1-up|SPP1-up GABBR2-up|IGF1-up HBEGF-down|LAMA3-down HBEGF-down|PDGFRA-down HBEGF-down|SPP1-up HBEGF-down|THBS1-down HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|IGF1-up HSPA1A-down|PDGFRA-down HSPA1A-down|PDGFRA-down HSPA1B-down|IGF1-up MMP2-up|ITGB4-up MMP2-up|LAMA3-down MMP2-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up	CAV2-down_858 JUN-down_3725|CAV2-down_858 MMP2-up_4313|CCND1-up_595 HBEGF-down_1839|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 MMP2-up_4313|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP2-up_4313|COL1A1-up_1277 HSPA1A-down_3303|COL1A1-up_1277 MMP2-up_4313|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 MMP2-up_4313|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP2-up_4313|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|SPP1-up_6696 GABBR1-up_2550|SPP1-up_6696 GABBR2-up_9568|IGF1-up_3479 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS1-down_7057 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|IGF1-up_3479 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1B-down_3304|IGF1-up_3479 MMP2-up_4313|ITGB4-up_3691 MMP2-up_4313|LAMA3-down_3909 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313
hsa04510	hsa04933	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CAV2-down CCND1-up|CAV2-down F3-down|CAV2-down JUN-down|CAV2-down MMP2-up|CAV2-down SERPINE1-down|CCND1-up FLT1-down|CCND1-up LAMA3-down|CCND1-up PDGFRA-down|CCND1-up THBS1-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up MMP2-up|CCND2-up SERPINE1-down|CCND2-up TGFB3-up|COL1A1-up FLT1-down|COL1A1-up ITGA10-down|COL1A1-up LAMA3-down|COL1A1-up PDGFRA-down|COL1A1-up THBS1-down|COL1A2-up FLT1-down|COL1A2-up LAMA3-down|COL1A2-up PDGFRA-down|COL1A2-up THBS1-down|COL6A1-up COL3A1-up|COL6A3-up COL3A1-up|COMP-up COL3A1-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|LAMA3-down COL3A1-up|PDGFRA-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COL6A1-up MMP2-up|COL6A1-up TGFB3-up|COL6A3-up MMP2-up|COL6A3-up TGFB3-up|COMP-up MMP2-up|COMP-up SERPINE1-down|COMP-up TGFB3-up|FLNC-up F3-down|FLT1-down F3-down|IGF1-up F3-down|PDGFRA-down F3-down|THBS1-down F3-down|THBS2-up F3-down|TNC-up F3-down|FLNC-up VCAM1-up|FLT1-down JUN-down|FLT1-down MMP2-up|FLT1-down SERPINE1-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|ITGB4-up MMP2-up|ITGB4-up VCAM1-up|ITGB8-up TGFB3-up|LAMA3-down MMP2-up|LAMA3-down SERPINE1-down|LAMA3-down VCAM1-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|PDGFRA-down TGFB3-up|PDGFRA-down VCAM1-up|SPP1-up SERPINE1-down|THBS1-down SERPINE1-down|THBS2-up SERPINE1-down|TNC-up SERPINE1-down|SPP1-up TGFB3-up|SPP1-up VCAM1-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CAV2-down_858 CCND1-up_595|CAV2-down_858 F3-down_2152|CAV2-down_858 JUN-down_3725|CAV2-down_858 MMP2-up_4313|CAV2-down_858 SERPINE1-down_5054|CCND1-up_595 FLT1-down_2321|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 PDGFRA-down_5156|CCND1-up_595 THBS1-down_7057|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 MMP2-up_4313|CCND2-up_894 SERPINE1-down_5054|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 THBS1-down_7057|COL6A1-up_1291 COL3A1-up_1281|COL6A3-up_1293 COL3A1-up_1281|COMP-up_1311 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|LAMA3-down_3909 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 MMP2-up_4313|COMP-up_1311 SERPINE1-down_5054|COMP-up_1311 TGFB3-up_7043|FLNC-up_2318 F3-down_2152|FLT1-down_2321 F3-down_2152|IGF1-up_3479 F3-down_2152|PDGFRA-down_5156 F3-down_2152|THBS1-down_7057 F3-down_2152|THBS2-up_7058 F3-down_2152|TNC-up_3371 F3-down_2152|FLNC-up_2318 VCAM1-up_7412|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 SERPINE1-down_5054|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 TGFB3-up_7043|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 SERPINE1-down_5054|LAMA3-down_3909 VCAM1-up_7412|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|PDGFRA-down_5156 TGFB3-up_7043|PDGFRA-down_5156 VCAM1-up_7412|SPP1-up_6696 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS2-up_7058 SERPINE1-down_5054|TNC-up_3371 SERPINE1-down_5054|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04510	hsa04974	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CAV2-down COL18A1-up|CCND1-up COL18A1-up|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up MME-down|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up MME-down|COMP-up COL10A1-up|SPP1-up COL10A1-up|THBS1-down COL10A1-up|COMP-up COL14A1-up|ITGB8-up COL14A1-up|JUN-down COL14A1-up|LAMA3-down COL14A1-up|THBS1-down COL14A1-up|THBS2-up COL14A1-up|COMP-up COL15A1-up|LAMA3-down COL15A1-up|THBS1-down COL15A1-up|THBS2-up COL15A1-up|TNC-up COL15A1-up|COMP-up COL17A1-up|ITGB4-up COL17A1-up|LAMA3-down COL17A1-up|THBS1-down COL17A1-up|THBS2-up COL17A1-up|COMP-up COL18A1-up|FIGF-down COL18A1-up|FLT1-down COL18A1-up|IGF1-up COL18A1-up|JUN-down COL18A1-up|LAMA3-down COL18A1-up|SPP1-up COL18A1-up|THBS1-down COL18A1-up|THBS2-up COL18A1-up|TNC-up COL18A1-up|COL1A1-up FIGF-down|COL1A1-up FLT1-down|COL1A1-up ITGA10-down|COL1A1-up JUN-down|COL1A1-up LAMA3-down|COL1A1-up PDGFRA-down|COL1A1-up THBS1-down|COL1A2-up FIGF-down|COL1A2-up FLT1-down|COL1A2-up JUN-down|COL1A2-up LAMA3-down|COL1A2-up PDGFRA-down|COL1A2-up THBS1-down|COMP-up COL3A1-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|JUN-down COL3A1-up|LAMA3-down COL3A1-up|PDGFRA-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COMP-up COL5A1-up|FLT1-down COL5A1-up|IGF1-up COL5A1-up|ITGA10-down COL5A1-up|ITGB4-up COL5A1-up|ITGB8-up COL5A1-up|JUN-down COL5A1-up|LAMA3-down COL5A1-up|PDGFRA-down COL5A1-up|SPP1-up COL5A1-up|THBS1-down COL5A1-up|THBS2-up COL5A1-up|TNC-up COL5A1-up|COMP-up COL5A2-up|ITGB4-up COL5A2-up|ITGB8-up COL5A2-up|JUN-down COL5A2-up|LAMA3-down COL5A2-up|SPP1-up COL5A2-up|THBS1-down COL5A2-up|THBS2-up COL5A2-up|TNC-up COL5A2-up|COL6A1-up JUN-down|COL6A1-up LAMA3-down|COL6A1-up PDGFRA-down|COL6A1-up THBS1-down|COL6A3-up JUN-down|COL6A3-up LAMA3-down|COL6A3-up PDGFRA-down|COL6A3-up THBS1-down|COMP-up COL7A1-up|ITGB4-up COL7A1-up|JUN-down COL7A1-up|LAMA3-down COL7A1-up|THBS1-down COL7A1-up|THBS2-up COL7A1-up|FLT1-down MME-down|IGF1-up MME-down|IGF1-up PRSS1-up|IGF1-up SLC1A1-down|ITGB4-up MME-down|JUN-down KCNN4-up|JUN-down MME-down|JUN-down PRSS1-up|PDGFRA-down MME-down|SPP1-up MME-down|THBS1-down MME-down	CAV2-down_858 COL18A1-up_80781|CCND1-up_595 COL18A1-up_80781|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 MME-down_4311|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 MME-down_4311|COMP-up_1311 COL10A1-up_1300|SPP1-up_6696 COL10A1-up_1300|THBS1-down_7057 COL10A1-up_1300|COMP-up_1311 COL14A1-up_7373|ITGB8-up_3696 COL14A1-up_7373|JUN-down_3725 COL14A1-up_7373|LAMA3-down_3909 COL14A1-up_7373|THBS1-down_7057 COL14A1-up_7373|THBS2-up_7058 COL14A1-up_7373|COMP-up_1311 COL15A1-up_1306|LAMA3-down_3909 COL15A1-up_1306|THBS1-down_7057 COL15A1-up_1306|THBS2-up_7058 COL15A1-up_1306|TNC-up_3371 COL15A1-up_1306|COMP-up_1311 COL17A1-up_1308|ITGB4-up_3691 COL17A1-up_1308|LAMA3-down_3909 COL17A1-up_1308|THBS1-down_7057 COL17A1-up_1308|THBS2-up_7058 COL17A1-up_1308|COMP-up_1311 COL18A1-up_80781|FIGF-down_2277 COL18A1-up_80781|FLT1-down_2321 COL18A1-up_80781|IGF1-up_3479 COL18A1-up_80781|JUN-down_3725 COL18A1-up_80781|LAMA3-down_3909 COL18A1-up_80781|SPP1-up_6696 COL18A1-up_80781|THBS1-down_7057 COL18A1-up_80781|THBS2-up_7058 COL18A1-up_80781|TNC-up_3371 COL18A1-up_80781|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 THBS1-down_7057|COMP-up_1311 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|JUN-down_3725 COL3A1-up_1281|LAMA3-down_3909 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COMP-up_1311 COL5A1-up_1289|FLT1-down_2321 COL5A1-up_1289|IGF1-up_3479 COL5A1-up_1289|ITGA10-down_8515 COL5A1-up_1289|ITGB4-up_3691 COL5A1-up_1289|ITGB8-up_3696 COL5A1-up_1289|JUN-down_3725 COL5A1-up_1289|LAMA3-down_3909 COL5A1-up_1289|PDGFRA-down_5156 COL5A1-up_1289|SPP1-up_6696 COL5A1-up_1289|THBS1-down_7057 COL5A1-up_1289|THBS2-up_7058 COL5A1-up_1289|TNC-up_3371 COL5A1-up_1289|COMP-up_1311 COL5A2-up_1290|ITGB4-up_3691 COL5A2-up_1290|ITGB8-up_3696 COL5A2-up_1290|JUN-down_3725 COL5A2-up_1290|LAMA3-down_3909 COL5A2-up_1290|SPP1-up_6696 COL5A2-up_1290|THBS1-down_7057 COL5A2-up_1290|THBS2-up_7058 COL5A2-up_1290|TNC-up_3371 COL5A2-up_1290|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 LAMA3-down_3909|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 THBS1-down_7057|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 LAMA3-down_3909|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 THBS1-down_7057|COMP-up_1311 COL7A1-up_1294|ITGB4-up_3691 COL7A1-up_1294|JUN-down_3725 COL7A1-up_1294|LAMA3-down_3909 COL7A1-up_1294|THBS1-down_7057 COL7A1-up_1294|THBS2-up_7058 COL7A1-up_1294|FLT1-down_2321 MME-down_4311|IGF1-up_3479 MME-down_4311|IGF1-up_3479 PRSS1-up_5644|IGF1-up_3479 SLC1A1-down_6505|ITGB4-up_3691 MME-down_4311|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MME-down_4311|JUN-down_3725 PRSS1-up_5644|PDGFRA-down_5156 MME-down_4311|SPP1-up_6696 MME-down_4311|THBS1-down_7057 MME-down_4311
hsa04510	hsa04978	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0	CAV2-down HMOX1-down|CAV2-down TF-up|CCND1-up HMOX1-down|CCND1-up TF-up|CCND2-up HMOX1-down|CCND2-up TF-up|COL1A1-up HMOX1-down|COL1A1-up TF-up|COL1A2-up HMOX1-down|COL1A2-up TF-up|COL6A1-up HMOX1-down|FIGF-down HMOX1-down|FLT1-down HMOX1-down|FLT1-down TF-up|IGF1-up HMOX1-down|JUN-down HMOX1-down|PDGFRA-down HMOX1-down|SPP1-up HMOX1-down|THBS1-down HMOX1-down|TNC-up HMOX1-down|IGF1-up TF-up|ITGB4-up MT1X-down|JUN-down MT1E-down|JUN-down MT1X-down|JUN-down MT2A-down|JUN-down TF-up|PDGFRA-down TF-up|SPP1-up TF-up|THBS1-down TF-up|TNC-up TF-up	CAV2-down_858 HMOX1-down_3162|CAV2-down_858 TF-up_7018|CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|CCND2-up_894 HMOX1-down_3162|CCND2-up_894 TF-up_7018|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 TF-up_7018|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 TF-up_7018|COL6A1-up_1291 HMOX1-down_3162|FIGF-down_2277 HMOX1-down_3162|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 TF-up_7018|IGF1-up_3479 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|PDGFRA-down_5156 HMOX1-down_3162|SPP1-up_6696 HMOX1-down_3162|THBS1-down_7057 HMOX1-down_3162|TNC-up_3371 HMOX1-down_3162|IGF1-up_3479 TF-up_7018|ITGB4-up_3691 MT1X-down_4501|JUN-down_3725 MT1E-down_4493|JUN-down_3725 MT1X-down_4501|JUN-down_3725 MT2A-down_4502|JUN-down_3725 TF-up_7018|PDGFRA-down_5156 TF-up_7018|SPP1-up_6696 TF-up_7018|THBS1-down_7057 TF-up_7018|TNC-up_3371 TF-up_7018
hsa04510	hsa05145	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0	CAV2-down LAMA3-down|CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up LDLR-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|COL1A1-up HSPA1A-down|COL1A1-up LDLR-down|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up TGFB3-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down HSPA1A-down|FLT1-down HSPA1B-down|FLT1-down JAK1-down|FLT1-down LDLR-down|FLT1-down TGFB3-up|IGF1-up HSPA1A-down|JUN-down HSPA1A-down|PDGFRA-down HSPA1A-down|JUN-down HSPA1B-down|PDGFRA-down HSPA1B-down|IGF1-up JAK1-down|IGF1-up LDLR-down|IGF1-up TGFB3-up|ITGA10-down LAMA3-down|ITGB8-up TGFB3-up|JUN-down JAK1-down|PDGFRA-down JAK1-down|JUN-down LAMA3-down|JUN-down LDLR-down|JUN-down TGFB3-up|THBS1-down LDLR-down|TNC-up LDLR-down|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CAV2-down_858 LAMA3-down_3909|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LDLR-down_3949|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 HSPA1A-down_3303|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 HSPA1A-down_3303|FLT1-down_2321 HSPA1B-down_3304|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 LDLR-down_3949|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 HSPA1A-down_3303|JUN-down_3725 HSPA1A-down_3303|PDGFRA-down_5156 HSPA1A-down_3303|JUN-down_3725 HSPA1B-down_3304|PDGFRA-down_5156 HSPA1B-down_3304|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 TGFB3-up_7043|ITGA10-down_8515 LAMA3-down_3909|ITGB8-up_3696 TGFB3-up_7043|JUN-down_3725 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 LDLR-down_3949|JUN-down_3725 TGFB3-up_7043|THBS1-down_7057 LDLR-down_3949|TNC-up_3371 LDLR-down_3949|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04510	hsa05146	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CAV2-down LAMA3-down|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up TGFB3-up|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up TGFB3-up|COL1A1-up FIGF-down|COL1A1-up FLT1-down|COL1A1-up ITGA10-down|COL1A1-up JUN-down|COL1A1-up PDGFRA-down|COL1A1-up THBS1-down|COL1A2-up FIGF-down|COL1A2-up FLT1-down|COL1A2-up JUN-down|COL1A2-up PDGFRA-down|COL1A2-up THBS1-down|COL6A1-up COL3A1-up|COL6A3-up COL3A1-up|COMP-up COL3A1-up|FLT1-down COL3A1-up|IGF1-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|JUN-down COL3A1-up|PDGFRA-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down TGFB3-up|IGF1-up TGFB3-up|SPP1-up IL1R2-down|ITGA10-down LAMA3-down|ITGB8-up TGFB3-up|JUN-down LAMA3-down|JUN-down SERPINB3-up|JUN-down TGFB3-up|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CAV2-down_858 LAMA3-down_3909|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 THBS1-down_7057|COL6A1-up_1291 COL3A1-up_1281|COL6A3-up_1293 COL3A1-up_1281|COMP-up_1311 COL3A1-up_1281|FLT1-down_2321 COL3A1-up_1281|IGF1-up_3479 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|JUN-down_3725 COL3A1-up_1281|PDGFRA-down_5156 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 TGFB3-up_7043|SPP1-up_6696 IL1R2-down_7850|ITGA10-down_8515 LAMA3-down_3909|ITGB8-up_3696 TGFB3-up_7043|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SERPINB3-up_6317|JUN-down_3725 TGFB3-up_7043|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04510	hsa05152	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up TGFB3-up|CCND2-up JAK1-down|CCND2-up TGFB3-up|COL1A1-up CD74-up|COL1A2-up CD74-up|FIGF-down CD74-up|IGF1-up CD74-up|JUN-down CD74-up|THBS1-down CD74-up|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up TGFB3-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|FIGF-down TGFB3-up|FLT1-down JAK1-down|FLT1-down TGFB3-up|IGF1-up JAK1-down|IGF1-up TGFB3-up|ITGB8-up TGFB3-up|JUN-down JAK1-down|PDGFRA-down JAK1-down|JUN-down TGFB3-up|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 JAK1-down_3716|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|JUN-down_3725 CD74-up_972|THBS1-down_7057 CD74-up_972|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 TGFB3-up_7043|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 TGFB3-up_7043|ITGB8-up_3696 TGFB3-up_7043|JUN-down_3725 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|JUN-down_3725 TGFB3-up_7043|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04510	hsa05160	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0	CCND1-up JAK1-down|CCND1-up LDLR-down|CCND1-up SOCS3-down|CCND2-up JAK1-down|CCND2-up SOCS3-down|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|FIGF-down CLDN5-down|FLT1-down CLDN5-down|IGF1-up CLDN5-down|JUN-down CLDN5-down|THBS1-down CLDN5-down|COL1A1-up LDLR-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|FLT1-down JAK1-down|FLT1-down LDLR-down|FLT1-down SOCS3-down|IGF1-up JAK1-down|IGF1-up LDLR-down|IGF1-up SOCS3-down|JUN-down JAK1-down|PDGFRA-down JAK1-down|JUN-down LDLR-down|JUN-down SOCS3-down|THBS1-down LDLR-down|TNC-up LDLR-down|PDGFRA-down SOCS3-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	CCND1-up_595 JAK1-down_3716|CCND1-up_595 LDLR-down_3949|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOCS3-down_9021|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|FLT1-down_2321 CLDN5-down_7122|IGF1-up_3479 CLDN5-down_7122|JUN-down_3725 CLDN5-down_7122|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 LDLR-down_3949|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LDLR-down_3949|IGF1-up_3479 SOCS3-down_9021|JUN-down_3725 JAK1-down_3716|PDGFRA-down_5156 JAK1-down_3716|JUN-down_3725 LDLR-down_3949|JUN-down_3725 SOCS3-down_9021|THBS1-down_7057 LDLR-down_3949|TNC-up_3371 LDLR-down_3949|PDGFRA-down_5156 SOCS3-down_9021|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04510	hsa05166	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	CAV2-down CCND1-up|CAV2-down JUN-down|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up LAMA3-down|CCND1-up THBS1-down|CCND2-up FLT1-down|CCND2-up THBS1-down|COL1A1-up MYB-up|COL1A1-up TGFB3-up|COL1A1-up VCAM1-up|COL1A2-up JAK1-down|COL1A2-up MYB-up|COL1A2-up TGFB3-up|COL6A1-up MYB-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|FIGF-down JUN-down|FIGF-down PDGFRA-down|FIGF-down TGFB3-up|FIGF-down VCAM1-up|FLNC-up MYB-up|FLNC-up VCAM1-up|FLT1-down FZD5-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MYB-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down VCAM1-up|ITGB8-up FZD5-down|IGF1-up JAK1-down|IGF1-up MYB-up|IGF1-up TGFB3-up|IGF1-up VCAM1-up|SPP1-up IL1R2-down|ITGB4-up MYB-up|ITGB4-up VCAM1-up|ITGB8-up TGFB3-up|LAMA3-down VCAM1-up|SPP1-up MYB-up|THBS1-down MYB-up|THBS2-up MYB-up|TNC-up MYB-up|SPP1-up TGFB3-up|SPP1-up VCAM1-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	CAV2-down_858 CCND1-up_595|CAV2-down_858 JUN-down_3725|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 THBS1-down_7057|CCND2-up_894 FLT1-down_2321|CCND2-up_894 THBS1-down_7057|COL1A1-up_1277 MYB-up_4602|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 MYB-up_4602|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 MYB-up_4602|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 VCAM1-up_7412|FLNC-up_2318 MYB-up_4602|FLNC-up_2318 VCAM1-up_7412|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MYB-up_4602|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 VCAM1-up_7412|ITGB8-up_3696 FZD5-down_7855|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 MYB-up_4602|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|SPP1-up_6696 IL1R2-down_7850|ITGB4-up_3691 MYB-up_4602|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 TGFB3-up_7043|LAMA3-down_3909 VCAM1-up_7412|SPP1-up_6696 MYB-up_4602|THBS1-down_7057 MYB-up_4602|THBS2-up_7058 MYB-up_4602|TNC-up_3371 MYB-up_4602|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04510	hsa05168	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	CAV2-down JUN-down|CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up SOCS3-down|CCND2-up JAK1-down|CCND2-up SOCS3-down|COL1A1-up CD74-up|COL1A2-up CD74-up|FIGF-down CD74-up|IGF1-up CD74-up|THBS1-down CD74-up|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|FIGF-down JUN-down|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down SOCS3-down|IGF1-up JAK1-down|IGF1-up SOCS3-down|PDGFRA-down JAK1-down|PDGFRA-down SOCS3-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	CAV2-down_858 JUN-down_3725|CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 SOCS3-down_9021|CCND2-up_894 JAK1-down_3716|CCND2-up_894 SOCS3-down_9021|COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|FIGF-down_2277 CD74-up_972|IGF1-up_3479 CD74-up_972|THBS1-down_7057 CD74-up_972|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|FIGF-down_2277 JUN-down_3725|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 SOCS3-down_9021|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 SOCS3-down_9021|PDGFRA-down_5156 JAK1-down_3716|PDGFRA-down_5156 SOCS3-down_9021|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04510	hsa05200	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	CAV2-down CCND1-up|CAV2-down JUN-down|CAV2-down LAMA3-down|CAV2-down MMP2-up|CCND1-up FLT1-down|CCND1-up THBS1-down|CCND2-up CXCL12-up|CCND2-up FZD5-down|CCND2-up HHIP-down|CCND2-up IGF1-up|CCND2-up JAK1-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up TCF7L2-up|CCND2-up TGFB3-up|CCND2-up ZBTB16-down|COL1A1-up CXCL12-up|COL1A1-up IGF1-up|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up TCF7L2-up|COL1A1-up TGFB3-up|COL1A1-up ZBTB16-down|COL1A2-up CXCL12-up|COL1A2-up EDNRB-down|COL1A2-up IGF1-up|COL1A2-up JAK1-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up TGFB3-up|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A1-up TGFB3-up|COL6A1-up ZBTB16-down|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COL6A3-up TGFB3-up|COMP-up CXCL12-up|COMP-up IGF1-up|COMP-up MMP1-up|COMP-up MMP2-up|COMP-up TGFB3-up|FLT1-down CXCL12-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|FLT1-down EDNRB-down|SPP1-up EDNRB-down|THBS1-down EDNRB-down|TNC-up EDNRB-down|FLT1-down FGF14-up|FLT1-down FZD5-down|FLT1-down IGF1-up|FLT1-down JAK1-down|FLT1-down JUN-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down PDGFRA-down|FLT1-down TGFB3-up|FLT1-down ZBTB16-down|ITGB8-up FZD5-down|IGF1-up THBS1-down|ITGA10-down LAMA3-down|ITGB4-up MMP1-up|ITGB4-up MMP2-up|ITGB8-up TGFB3-up|SPP1-up MMP1-up|THBS1-down MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down ZBTB16-down	CAV2-down_858 CCND1-up_595|CAV2-down_858 JUN-down_3725|CAV2-down_858 LAMA3-down_3909|CAV2-down_858 MMP2-up_4313|CCND1-up_595 FLT1-down_2321|CCND1-up_595 THBS1-down_7057|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HHIP-down_64399|CCND2-up_894 IGF1-up_3479|CCND2-up_894 JAK1-down_3716|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 TCF7L2-up_6934|CCND2-up_894 TGFB3-up_7043|CCND2-up_894 ZBTB16-down_7704|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 TCF7L2-up_6934|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 EDNRB-down_1910|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 TGFB3-up_7043|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 IGF1-up_3479|COMP-up_1311 MMP1-up_4312|COMP-up_1311 MMP2-up_4313|COMP-up_1311 TGFB3-up_7043|FLT1-down_2321 CXCL12-up_6387|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|FLT1-down_2321 EDNRB-down_1910|SPP1-up_6696 EDNRB-down_1910|THBS1-down_7057 EDNRB-down_1910|TNC-up_3371 EDNRB-down_1910|FLT1-down_2321 FGF14-up_2259|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 JAK1-down_3716|FLT1-down_2321 JUN-down_3725|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 ZBTB16-down_7704|ITGB8-up_3696 FZD5-down_7855|IGF1-up_3479 THBS1-down_7057|ITGA10-down_8515 LAMA3-down_3909|ITGB4-up_3691 MMP1-up_4312|ITGB4-up_3691 MMP2-up_4313|ITGB8-up_3696 TGFB3-up_7043|SPP1-up_6696 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 ZBTB16-down_7704
hsa04510	hsa05202	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.027	CAV2-down SIX1-up|CCND1-up CCND2-up|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up JUN-down|CCND2-up PDGFRA-down|CCND2-up THBS1-down|COL1A1-up IGF1-up|COL1A1-up PLAU-up|COL1A1-up PROM1-up|COL1A1-up SIX1-up|COL1A1-up ZBTB16-down|COL1A2-up IGF1-up|COL1A2-up PLAU-up|COL6A1-up ZBTB16-down|COL6A3-up PLAU-up|COMP-up IGF1-up|FIGF-down FLT1-down|FIGF-down IGF1-up|FIGF-down PLAU-up|FIGF-down PROM1-up|IGF1-up JUN-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|SPP1-up IL1R2-down|ITGB4-up PLAU-up|ITGB4-up PROM1-up|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|LAMA3-down PLAU-up|PDGFRA-down PLAU-up|PDGFRA-down PROM1-up|PDGFRA-down ZBTB16-down|SPP1-up PLAU-up|THBS1-down PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up|THBS1-down PROM1-up|TNC-up PROM1-up|THBS1-down ZBTB16-down	CAV2-down_858 SIX1-up_6495|CCND1-up_595 CCND2-up_894|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 JUN-down_3725|CCND2-up_894 PDGFRA-down_5156|CCND2-up_894 THBS1-down_7057|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 PROM1-up_8842|COL1A1-up_1277 SIX1-up_6495|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 PLAU-up_5328|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 IGF1-up_3479|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 PROM1-up_8842|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|SPP1-up_6696 IL1R2-down_7850|ITGB4-up_3691 PLAU-up_5328|ITGB4-up_3691 PROM1-up_8842|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|LAMA3-down_3909 PLAU-up_5328|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 PROM1-up_8842|PDGFRA-down_5156 ZBTB16-down_7704|SPP1-up_6696 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328|THBS1-down_7057 PROM1-up_8842|TNC-up_3371 PROM1-up_8842|THBS1-down_7057 ZBTB16-down_7704
hsa04510	hsa05205	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	FLT1-down ANK2-up|PDGFRA-down ANK2-up|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up LAMA3-down|CCND1-up PDGFRA-down|CCND2-up FZD5-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|COL1A1-up IGF1-up|COL1A1-up MMP2-up|COL1A1-up PLAU-up|COL1A2-up IGF1-up|COL1A2-up MMP2-up|COL1A2-up PLAU-up|COL6A1-up MMP2-up|COL6A3-up MMP2-up|COL6A3-up PLAU-up|COMP-up IGF1-up|COMP-up MMP2-up|FIGF-down HBEGF-down|FIGF-down IGF1-up|FIGF-down MMP2-up|FIGF-down PLAU-up|FIGF-down THBS1-down|FLNC-up JUN-down|FLT1-down FZD5-down|FLT1-down HBEGF-down|FLT1-down IGF1-up|FLT1-down MMP2-up|FLT1-down PLAU-up|FLT1-down THBS1-down|ITGB8-up FZD5-down|JUN-down FZD5-down|PDGFRA-down FZD5-down|JUN-down HBEGF-down|LAMA3-down HBEGF-down|PDGFRA-down HBEGF-down|SPP1-up HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|ITGB4-up MMP2-up|ITGB4-up PLAU-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|LAMA3-down MMP2-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|PDGFRA-down PLAU-up|PDGFRA-down THBS1-down|SPP1-up PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up	FLT1-down_2321 ANK2-up_287|PDGFRA-down_5156 ANK2-up_287|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 PDGFRA-down_5156|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PLAU-up_5328|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PLAU-up_5328|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 IGF1-up_3479|COMP-up_1311 MMP2-up_4313|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FLNC-up_2318 JUN-down_3725|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 THBS1-down_7057|ITGB8-up_3696 FZD5-down_7855|JUN-down_3725 FZD5-down_7855|PDGFRA-down_5156 FZD5-down_7855|JUN-down_3725 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 PLAU-up_5328|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 THBS1-down_7057|SPP1-up_6696 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328
hsa04510	hsa05206	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CAV2-down CCND1-up|CAV2-down HMOX1-down|CAV2-down SERPINB5-up|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up LAMA3-down|CCND2-up FLT1-down|CCND2-up JUN-down|COL1A1-up CYP24A1-up|COL1A1-up HMOX1-down|COL1A1-up MMP16-up|COL1A1-up PLAU-up|COL1A1-up SOX4-up|COL1A1-up TNC-up|COL1A2-up HMOX1-down|COL1A2-up MMP16-up|COL1A2-up PLAU-up|COL1A2-up TNC-up|COL6A1-up HMOX1-down|COL6A1-up MMP16-up|COL6A1-up TNC-up|COL6A3-up PLAU-up|COL6A3-up TNC-up|COMP-up MMP16-up|COMP-up TNC-up|IGF1-up CYP24A1-up|JUN-down CYP24A1-up|SPP1-up CYP24A1-up|FIGF-down HMOX1-down|FIGF-down PDGFRA-down|FIGF-down PLAU-up|FIGF-down THBS1-down|FIGF-down TNC-up|FLNC-up MMP16-up|FLNC-up TNC-up|FLNC-up TP63-up|FLT1-down HMOX1-down|FLT1-down IRS2-down|FLT1-down MCL1-down|FLT1-down MMP16-up|FLT1-down PDGFRA-down|FLT1-down PLAU-up|FLT1-down SERPINB5-up|FLT1-down THBS1-down|FLT1-down TNC-up|FLT1-down TP63-up|IGF1-up HMOX1-down|JUN-down HMOX1-down|SPP1-up HMOX1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up TNC-up|JUN-down IRS2-down|SPP1-up IRS2-down|ITGB4-up MCL1-down|ITGB4-up PLAU-up|ITGB4-up SERPINB5-up|ITGB4-up TNC-up|ITGB8-up MCL1-down|ITGB8-up TNC-up|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|LAMA3-down TNC-up|SPP1-up MCL1-down|THBS2-up MMP16-up|SPP1-up PLAU-up|THBS2-up PLAU-up|SPP1-up SERPINB5-up|THBS2-up SERPINB5-up|SPP1-up TNC-up|SPP1-up TP63-up|THBS2-up TNC-up	CAV2-down_858 CCND1-up_595|CAV2-down_858 HMOX1-down_3162|CAV2-down_858 SERPINB5-up_5268|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 LAMA3-down_3909|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JUN-down_3725|COL1A1-up_1277 CYP24A1-up_1591|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 MMP16-up_4325|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SOX4-up_6659|COL1A1-up_1277 TNC-up_3371|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 MMP16-up_4325|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 TNC-up_3371|COL6A1-up_1291 HMOX1-down_3162|COL6A1-up_1291 MMP16-up_4325|COL6A1-up_1291 TNC-up_3371|COL6A3-up_1293 PLAU-up_5328|COL6A3-up_1293 TNC-up_3371|COMP-up_1311 MMP16-up_4325|COMP-up_1311 TNC-up_3371|IGF1-up_3479 CYP24A1-up_1591|JUN-down_3725 CYP24A1-up_1591|SPP1-up_6696 CYP24A1-up_1591|FIGF-down_2277 HMOX1-down_3162|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 TNC-up_3371|FLNC-up_2318 MMP16-up_4325|FLNC-up_2318 TNC-up_3371|FLNC-up_2318 TP63-up_8626|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 MMP16-up_4325|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 TNC-up_3371|FLT1-down_2321 TP63-up_8626|IGF1-up_3479 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|SPP1-up_6696 HMOX1-down_3162|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 TNC-up_3371|JUN-down_3725 IRS2-down_8660|SPP1-up_6696 IRS2-down_8660|ITGB4-up_3691 MCL1-down_4170|ITGB4-up_3691 PLAU-up_5328|ITGB4-up_3691 SERPINB5-up_5268|ITGB4-up_3691 TNC-up_3371|ITGB8-up_3696 MCL1-down_4170|ITGB8-up_3696 TNC-up_3371|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|LAMA3-down_3909 TNC-up_3371|SPP1-up_6696 MCL1-down_4170|THBS2-up_7058 MMP16-up_4325|SPP1-up_6696 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|SPP1-up_6696 SERPINB5-up_5268|THBS2-up_7058 SERPINB5-up_5268|SPP1-up_6696 TNC-up_3371|SPP1-up_6696 TP63-up_8626|THBS2-up_7058 TNC-up_3371
hsa04510	hsa05219	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CAV2-down CCND1-up|CAV2-down MMP2-up|CCND1-up FIGF-down|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up LAMA3-down|CCND1-up PDGFRA-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COMP-up MMP1-up|COMP-up MMP2-up|FIGF-down HBEGF-down|FIGF-down MMP1-up|FIGF-down MMP2-up|FIGF-down THBS1-down|FLT1-down HBEGF-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down THBS1-down|IGF1-up HBEGF-down|JUN-down HBEGF-down|LAMA3-down HBEGF-down|PDGFRA-down HBEGF-down|SPP1-up HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|IGF1-up MMP1-up|IGF1-up MMP2-up|ITGB4-up MMP1-up|ITGB4-up MMP2-up|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|LAMA3-down MMP1-up|LAMA3-down MMP2-up|LAMA3-down THBS1-down|PDGFRA-down MMP1-up|SPP1-up MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|PDGFRA-down MMP2-up|SPP1-up MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|PDGFRA-down THBS1-down	CAV2-down_858 CCND1-up_595|CAV2-down_858 MMP2-up_4313|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 PDGFRA-down_5156|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 MMP1-up_4312|COMP-up_1311 MMP2-up_4313|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 THBS1-down_7057|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|JUN-down_3725 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|ITGB4-up_3691 MMP1-up_4312|ITGB4-up_3691 MMP2-up_4313|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|LAMA3-down_3909 MMP1-up_4312|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 THBS1-down_7057|PDGFRA-down_5156 MMP1-up_4312|SPP1-up_6696 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|PDGFRA-down_5156 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057
hsa04510	hsa05323	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CAV2-down JUN-down|CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up MMP1-up|CCND2-up TGFB3-up|COL1A1-up CTSK-up|COL1A1-up CXCL12-up|COL1A1-up MMP1-up|COL1A1-up TGFB3-up|COL1A2-up CTSK-up|COL1A2-up CXCL12-up|COL1A2-up MMP1-up|COL1A2-up TGFB3-up|COL6A1-up CTSK-up|COL6A1-up MMP1-up|COL6A1-up TGFB3-up|COL6A3-up CTSK-up|COL6A3-up MMP1-up|COL6A3-up TGFB3-up|COMP-up CTSK-up|COMP-up CXCL12-up|COMP-up MMP1-up|COMP-up TGFB3-up|IGF1-up CTSK-up|SPP1-up CTSK-up|THBS1-down CTSK-up|THBS2-up CTSK-up|TNC-up CTSK-up|FIGF-down CXCL12-up|IGF1-up CXCL12-up|PDGFRA-down CXCL12-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|FIGF-down FLT1-down|FIGF-down JUN-down|FIGF-down MMP1-up|FIGF-down TGFB3-up|IGF1-up MMP1-up|IGF1-up TGFB3-up|ITGB4-up MMP1-up|ITGB8-up TGFB3-up|LAMA3-down MMP1-up|PDGFRA-down MMP1-up|SPP1-up MMP1-up|THBS1-down MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	CAV2-down_858 JUN-down_3725|CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 CTSK-up_1513|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 CTSK-up_1513|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 CTSK-up_1513|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 CTSK-up_1513|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 CTSK-up_1513|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 MMP1-up_4312|COMP-up_1311 TGFB3-up_7043|IGF1-up_3479 CTSK-up_1513|SPP1-up_6696 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|THBS2-up_7058 CTSK-up_1513|TNC-up_3371 CTSK-up_1513|FIGF-down_2277 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 TGFB3-up_7043|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|ITGB4-up_3691 MMP1-up_4312|ITGB8-up_3696 TGFB3-up_7043|LAMA3-down_3909 MMP1-up_4312|PDGFRA-down_5156 MMP1-up_4312|SPP1-up_6696 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04510	hsa05410	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	CAV2-down ITGB4-up|CAV2-down ITGB8-up|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COMP-up IGF1-up|COMP-up ITGB4-up|COMP-up ITGB8-up|COMP-up TGFB3-up|FLNC-up DES-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TTN-down|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|ITGB4-up JUN-down|ITGB4-up LAMA3-down|ITGB4-up PDGFRA-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up THBS1-down|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|SPP1-up TTN-down|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|TNC-up TNNC1-down	CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COMP-up_1311 IGF1-up_3479|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|COMP-up_1311 TGFB3-up_7043|FLNC-up_2318 DES-up_1674|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TTN-down_7273|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa04510	hsa05412	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CAV2-down CDH2-up|CAV2-down ITGB4-up|CAV2-down ITGB8-up|CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|COL1A1-up CDH2-up|COL1A2-up CDH2-up|COMP-up CDH2-up|FIGF-down CDH2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|JUN-down CDH2-up|PDGFRA-down CDH2-up|SPP1-up CDH2-up|THBS1-down CDH2-up|THBS2-up CDH2-up|TNC-up CDH2-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TCF7L2-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COMP-up ITGB4-up|COMP-up ITGB8-up|FLNC-up DES-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLT1-down ITGB4-up|IGF1-up TCF7L2-up|ITGB4-up JUN-down|ITGB4-up LAMA3-down|ITGB4-up PDGFRA-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up THBS1-down|JUN-down TCF7L2-up|PDGFRA-down TCF7L2-up	CAV2-down_858 CDH2-up_1000|CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COMP-up_1311 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|SPP1-up_6696 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS2-up_7058 CDH2-up_1000|TNC-up_3371 CDH2-up_1000|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TCF7L2-up_6934|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|FLNC-up_2318 DES-up_1674|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLT1-down_2321 ITGB4-up_3691|IGF1-up_3479 TCF7L2-up_6934|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057|JUN-down_3725 TCF7L2-up_6934|PDGFRA-down_5156 TCF7L2-up_6934
hsa04510	hsa05414	Focal adhesion - Homo sapiens (human)	CAV2,FIGF,FLT1,ITGA10,JUN,LAMA3,PDGFRA,THBS1,CCND1,CCND2,COL1A1,COL1A2,COL6A1,COL6A3,COMP,FLNC,IGF1,ITGB4,ITGB8,SPP1,THBS2,TNC	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	FLT1-down ADRB1-down|SPP1-up ADRB1-down|CAV2-down ITGB4-up|CAV2-down ITGB8-up|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up PLN-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COMP-up IGF1-up|COMP-up ITGB4-up|COMP-up ITGB8-up|COMP-up PLN-up|COMP-up TGFB3-up|FLNC-up DES-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TTN-down|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|ITGB4-up JUN-down|ITGB4-up LAMA3-down|ITGB4-up PDGFRA-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up THBS1-down|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down|PDGFRA-down TGFB3-up|SPP1-up TGFB3-up|SPP1-up TTN-down|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|TNC-up TNNC1-down	FLT1-down_2321 ADRB1-down_153|SPP1-up_6696 ADRB1-down_153|CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 PLN-up_5350|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COMP-up_1311 IGF1-up_3479|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|COMP-up_1311 PLN-up_5350|COMP-up_1311 TGFB3-up_7043|FLNC-up_2318 DES-up_1674|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TTN-down_7273|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|PDGFRA-down_5156 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa04512	hsa04514	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	0	AGRN-up NCAM1-up|COL1A1-up CDH2-up|COL1A2-up CDH2-up|COMP-up CDH2-up|ITGB4-up CDH2-up|SPP1-up CDH2-up|THBS1-down CDH2-up|THBS2-up CDH2-up|TNC-up CDH2-up|LAMA3-down CDH3-up|TNC-up CDH3-up|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|THBS1-down CLDN5-down|COL1A1-up ITGB8-up|COL1A1-up VCAM1-up|COL1A2-up ITGB8-up|COL1A2-up NCAM1-up|COL6A1-up ITGB8-up|COL6A3-up ITGB8-up|COMP-up ITGB8-up|ITGA10-down ITGB8-up|ITGB4-up ITGB8-up|ITGB4-up NCAM1-up|ITGB4-up VCAM1-up|ITGB8-up LAMA3-down|ITGB8-up THBS1-down|LAMA3-down VCAM1-up|SPP1-up NCAM1-up|THBS1-down NCAM1-up|TNC-up NCAM1-up|TNC-up NFASC-up|SPP1-up VCAM1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	AGRN-up_375790 NCAM1-up_4684|COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COMP-up_1311 CDH2-up_1000|ITGB4-up_3691 CDH2-up_1000|SPP1-up_6696 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS2-up_7058 CDH2-up_1000|TNC-up_3371 CDH2-up_1000|LAMA3-down_3909 CDH3-up_1001|TNC-up_3371 CDH3-up_1001|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 NCAM1-up_4684|COL6A1-up_1291 ITGB8-up_3696|COL6A3-up_1293 ITGB8-up_3696|COMP-up_1311 ITGB8-up_3696|ITGA10-down_8515 ITGB8-up_3696|ITGB4-up_3691 ITGB8-up_3696|ITGB4-up_3691 NCAM1-up_4684|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057|LAMA3-down_3909 VCAM1-up_7412|SPP1-up_6696 NCAM1-up_4684|THBS1-down_7057 NCAM1-up_4684|TNC-up_3371 NCAM1-up_4684|TNC-up_3371 NFASC-up_23114|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04512	hsa04550	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0.001	COL1A1-up IGF1-up|COL1A1-up SOX2-up|COL1A2-up IGF1-up|COL1A2-up JAK1-down|COL1A2-up SOX2-up|COMP-up IGF1-up|ITGB8-up FZD5-down|SPP1-up ID1-down|THBS1-down ID1-down|THBS2-up ID1-down|SPP1-up IGF1-up|THBS1-down IGF1-up|THBS2-up IGF1-up|TNC-up IGF1-up|SPP1-up LIFR-down|SPP1-up SOX2-up|THBS1-down SOX2-up|TNC-up SOX2-up	COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 SOX2-up_6657|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 SOX2-up_6657|COMP-up_1311 IGF1-up_3479|ITGB8-up_3696 FZD5-down_7855|SPP1-up_6696 ID1-down_3397|THBS1-down_7057 ID1-down_3397|THBS2-up_7058 ID1-down_3397|SPP1-up_6696 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|THBS2-up_7058 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|SPP1-up_6696 LIFR-down_3977|SPP1-up_6696 SOX2-up_6657|THBS1-down_7057 SOX2-up_6657|TNC-up_3371 SOX2-up_6657
hsa04512	hsa04610	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0	AGRN-up C7-up|SPP1-up CFH-up|THBS1-down CFH-up|COL1A1-up PLAU-up|COL1A1-up SERPINE1-down|COL1A2-up PLAU-up|COL1A2-up SERPINE1-down|COL6A3-up PLAU-up|COMP-up SERPINE1-down|THBS1-down F3-down|THBS2-up F3-down|TNC-up F3-down|ITGB4-up PLAU-up|LAMA3-down PLAU-up|LAMA3-down SERPINE1-down|SPP1-up PLAU-up|THBS1-down PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up|SPP1-up SERPINE1-down|THBS1-down SERPINE1-down|THBS2-up SERPINE1-down|TNC-up SERPINE1-down|SPP1-up TFPI-down|THBS1-down TFPI-down|THBS2-up TFPI-down|TNC-up TFPI-down	AGRN-up_375790 C7-up_730|SPP1-up_6696 CFH-up_3075|THBS1-down_7057 CFH-up_3075|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SERPINE1-down_5054|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 SERPINE1-down_5054|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 SERPINE1-down_5054|THBS1-down_7057 F3-down_2152|THBS2-up_7058 F3-down_2152|TNC-up_3371 F3-down_2152|ITGB4-up_3691 PLAU-up_5328|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 SERPINE1-down_5054|SPP1-up_6696 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328|SPP1-up_6696 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS2-up_7058 SERPINE1-down_5054|TNC-up_3371 SERPINE1-down_5054|SPP1-up_6696 TFPI-down_7035|THBS1-down_7057 TFPI-down_7035|THBS2-up_7058 TFPI-down_7035|TNC-up_3371 TFPI-down_7035
hsa04512	hsa04630	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0.013	COL1A1-up CCND1-up|COL1A2-up CCND1-up|ITGB4-up CCND1-up|LAMA3-down CCND1-up|SPP1-up CCND1-up|THBS1-down CCND1-up|THBS2-up CCND1-up|TNC-up CCND1-up|COL1A2-up CCND2-up|THBS1-down CCND2-up|TNC-up CCND2-up|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|ITGB4-up MCL1-down|ITGB8-up MCL1-down|SPP1-up LIFR-down|SPP1-up MCL1-down|THBS1-down MCL1-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|ITGB4-up_3691 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|SPP1-up_6696 CCND1-up_595|THBS1-down_7057 CCND1-up_595|THBS2-up_7058 CCND1-up_595|TNC-up_3371 CCND1-up_595|COL1A2-up_1278 CCND2-up_894|THBS1-down_7057 CCND2-up_894|TNC-up_3371 CCND2-up_894|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|ITGB4-up_3691 MCL1-down_4170|ITGB8-up_3696 MCL1-down_4170|SPP1-up_6696 LIFR-down_3977|SPP1-up_6696 MCL1-down_4170|THBS1-down_7057 MCL1-down_4170|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04512	hsa04668	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.003	COL1A1-up CXCL2-down|COL1A1-up JUN-down|COL1A1-up SOCS3-down|COL1A1-up VCAM1-up|COL1A2-up JUN-down|COL6A1-up JUN-down|COL6A3-up JUN-down|COMP-up JUN-down|SPP1-up CXCL2-down|ITGB4-up JUN-down|ITGB4-up VCAM1-up|LAMA3-down JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down VCAM1-up|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down|SPP1-up VCAM1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	COL1A1-up_1277 CXCL2-down_2920|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SOCS3-down_9021|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JUN-down_3725|COL6A1-up_1291 JUN-down_3725|COL6A3-up_1293 JUN-down_3725|COMP-up_1311 JUN-down_3725|SPP1-up_6696 CXCL2-down_2920|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 VCAM1-up_7412|LAMA3-down_3909 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 VCAM1-up_7412|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04512	hsa04670	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|THBS1-down CLDN5-down|COL1A1-up CXCL12-up|COL1A1-up MMP2-up|COL1A1-up THY1-up|COL1A1-up VCAM1-up|COL1A2-up CXCL12-up|COL1A2-up MMP2-up|COL6A1-up MMP2-up|COL6A3-up MMP2-up|COMP-up CXCL12-up|COMP-up MMP2-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|ITGB4-up MMP2-up|ITGB4-up THY1-up|ITGB4-up VCAM1-up|LAMA3-down MMP2-up|LAMA3-down VCAM1-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|SPP1-up THY1-up|SPP1-up VCAM1-up|THBS1-down THY1-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 THY1-up_7070|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 MMP2-up_4313|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 THY1-up_7070|ITGB4-up_3691 VCAM1-up_7412|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 VCAM1-up_7412|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|SPP1-up_6696 THY1-up_7070|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 THY1-up_7070|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04512	hsa04915	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	COL1A1-up HSPA1A-down|COL1A1-up JUN-down|COL1A1-up MMP2-up|COL1A2-up JUN-down|COL1A2-up MMP2-up|COL6A1-up JUN-down|COL6A1-up MMP2-up|COL6A3-up JUN-down|COL6A3-up MMP2-up|COMP-up JUN-down|COMP-up MMP2-up|SPP1-up GABBR1-up|SPP1-up GABBR2-up|LAMA3-down HBEGF-down|SPP1-up HBEGF-down|THBS1-down HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|ITGB4-up JUN-down|ITGB4-up MMP2-up|LAMA3-down JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down MMP2-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up	COL1A1-up_1277 HSPA1A-down_3303|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP2-up_4313|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP2-up_4313|SPP1-up_6696 GABBR1-up_2550|SPP1-up_6696 GABBR2-up_9568|LAMA3-down_3909 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS1-down_7057 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP2-up_4313|LAMA3-down_3909 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 MMP2-up_4313|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313
hsa04512	hsa04933	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	ITGB4-up CCND1-up|LAMA3-down CCND1-up|SPP1-up CCND1-up|THBS1-down CCND1-up|THBS2-up CCND1-up|TNC-up CCND1-up|COL1A1-up ITGA10-down|COL1A1-up LAMA3-down|COL1A1-up THBS1-down|COL1A2-up LAMA3-down|COL1A2-up THBS1-down|COL6A1-up COL3A1-up|COL6A3-up COL3A1-up|COMP-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|LAMA3-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COL6A1-up JUN-down|COL6A1-up MMP2-up|COL6A1-up TGFB3-up|COL6A3-up JUN-down|COL6A3-up MMP2-up|COL6A3-up TGFB3-up|COMP-up JUN-down|COMP-up MMP2-up|COMP-up SERPINE1-down|COMP-up TGFB3-up|THBS1-down F3-down|THBS2-up F3-down|TNC-up F3-down|SPP1-up FIGF-down|THBS1-down FIGF-down|THBS2-up FIGF-down|TNC-up FIGF-down|ITGB4-up JUN-down|ITGB4-up MMP2-up|ITGB4-up VCAM1-up|ITGB8-up TGFB3-up|LAMA3-down JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down MMP2-up|LAMA3-down SERPINE1-down|LAMA3-down VCAM1-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|SPP1-up SERPINE1-down|THBS1-down SERPINE1-down|THBS2-up SERPINE1-down|TNC-up SERPINE1-down|SPP1-up TGFB3-up|SPP1-up VCAM1-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	ITGB4-up_3691 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|SPP1-up_6696 CCND1-up_595|THBS1-down_7057 CCND1-up_595|THBS2-up_7058 CCND1-up_595|TNC-up_3371 CCND1-up_595|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 THBS1-down_7057|COL6A1-up_1291 COL3A1-up_1281|COL6A3-up_1293 COL3A1-up_1281|COMP-up_1311 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|LAMA3-down_3909 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP2-up_4313|COMP-up_1311 SERPINE1-down_5054|COMP-up_1311 TGFB3-up_7043|THBS1-down_7057 F3-down_2152|THBS2-up_7058 F3-down_2152|TNC-up_3371 F3-down_2152|SPP1-up_6696 FIGF-down_2277|THBS1-down_7057 FIGF-down_2277|THBS2-up_7058 FIGF-down_2277|TNC-up_3371 FIGF-down_2277|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 TGFB3-up_7043|LAMA3-down_3909 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 SERPINE1-down_5054|LAMA3-down_3909 VCAM1-up_7412|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|SPP1-up_6696 SERPINE1-down_5054|THBS1-down_7057 SERPINE1-down_5054|THBS2-up_7058 SERPINE1-down_5054|TNC-up_3371 SERPINE1-down_5054|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04512	hsa04974	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	AGRN-up COL15A1-up|AGRN-up COL18A1-up|AGRN-up SLC1A1-down|COMP-up COL10A1-up|SPP1-up COL10A1-up|THBS1-down COL10A1-up|COMP-up COL14A1-up|ITGB8-up COL14A1-up|LAMA3-down COL14A1-up|THBS1-down COL14A1-up|THBS2-up COL14A1-up|COMP-up COL15A1-up|LAMA3-down COL15A1-up|THBS1-down COL15A1-up|THBS2-up COL15A1-up|TNC-up COL15A1-up|COMP-up COL17A1-up|ITGB4-up COL17A1-up|LAMA3-down COL17A1-up|THBS1-down COL17A1-up|THBS2-up COL17A1-up|COMP-up COL18A1-up|LAMA3-down COL18A1-up|SPP1-up COL18A1-up|THBS1-down COL18A1-up|THBS2-up COL18A1-up|TNC-up COL18A1-up|COL1A1-up ITGA10-down|COL1A1-up LAMA3-down|COL1A1-up THBS1-down|COL1A2-up LAMA3-down|COL1A2-up THBS1-down|COMP-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|LAMA3-down COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COMP-up COL5A1-up|ITGA10-down COL5A1-up|ITGB4-up COL5A1-up|ITGB8-up COL5A1-up|LAMA3-down COL5A1-up|SPP1-up COL5A1-up|THBS1-down COL5A1-up|THBS2-up COL5A1-up|TNC-up COL5A1-up|COMP-up COL5A2-up|ITGB4-up COL5A2-up|ITGB8-up COL5A2-up|LAMA3-down COL5A2-up|SPP1-up COL5A2-up|THBS1-down COL5A2-up|THBS2-up COL5A2-up|TNC-up COL5A2-up|COL6A1-up LAMA3-down|COL6A1-up THBS1-down|COL6A3-up LAMA3-down|COL6A3-up THBS1-down|COMP-up COL7A1-up|ITGB4-up COL7A1-up|LAMA3-down COL7A1-up|THBS1-down COL7A1-up|THBS2-up COL7A1-up|ITGB4-up MME-down|SPP1-up MME-down|THBS1-down MME-down	AGRN-up_375790 COL15A1-up_1306|AGRN-up_375790 COL18A1-up_80781|AGRN-up_375790 SLC1A1-down_6505|COMP-up_1311 COL10A1-up_1300|SPP1-up_6696 COL10A1-up_1300|THBS1-down_7057 COL10A1-up_1300|COMP-up_1311 COL14A1-up_7373|ITGB8-up_3696 COL14A1-up_7373|LAMA3-down_3909 COL14A1-up_7373|THBS1-down_7057 COL14A1-up_7373|THBS2-up_7058 COL14A1-up_7373|COMP-up_1311 COL15A1-up_1306|LAMA3-down_3909 COL15A1-up_1306|THBS1-down_7057 COL15A1-up_1306|THBS2-up_7058 COL15A1-up_1306|TNC-up_3371 COL15A1-up_1306|COMP-up_1311 COL17A1-up_1308|ITGB4-up_3691 COL17A1-up_1308|LAMA3-down_3909 COL17A1-up_1308|THBS1-down_7057 COL17A1-up_1308|THBS2-up_7058 COL17A1-up_1308|COMP-up_1311 COL18A1-up_80781|LAMA3-down_3909 COL18A1-up_80781|SPP1-up_6696 COL18A1-up_80781|THBS1-down_7057 COL18A1-up_80781|THBS2-up_7058 COL18A1-up_80781|TNC-up_3371 COL18A1-up_80781|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 THBS1-down_7057|COMP-up_1311 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|LAMA3-down_3909 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COMP-up_1311 COL5A1-up_1289|ITGA10-down_8515 COL5A1-up_1289|ITGB4-up_3691 COL5A1-up_1289|ITGB8-up_3696 COL5A1-up_1289|LAMA3-down_3909 COL5A1-up_1289|SPP1-up_6696 COL5A1-up_1289|THBS1-down_7057 COL5A1-up_1289|THBS2-up_7058 COL5A1-up_1289|TNC-up_3371 COL5A1-up_1289|COMP-up_1311 COL5A2-up_1290|ITGB4-up_3691 COL5A2-up_1290|ITGB8-up_3696 COL5A2-up_1290|LAMA3-down_3909 COL5A2-up_1290|SPP1-up_6696 COL5A2-up_1290|THBS1-down_7057 COL5A2-up_1290|THBS2-up_7058 COL5A2-up_1290|TNC-up_3371 COL5A2-up_1290|COL6A1-up_1291 LAMA3-down_3909|COL6A1-up_1291 THBS1-down_7057|COL6A3-up_1293 LAMA3-down_3909|COL6A3-up_1293 THBS1-down_7057|COMP-up_1311 COL7A1-up_1294|ITGB4-up_3691 COL7A1-up_1294|LAMA3-down_3909 COL7A1-up_1294|THBS1-down_7057 COL7A1-up_1294|THBS2-up_7058 COL7A1-up_1294|ITGB4-up_3691 MME-down_4311|SPP1-up_6696 MME-down_4311|THBS1-down_7057 MME-down_4311
hsa04512	hsa04978	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.013	COL1A1-up HMOX1-down|COL1A1-up TF-up|COL1A2-up HMOX1-down|COL1A2-up TF-up|COL6A1-up HMOX1-down|SPP1-up HMOX1-down|THBS1-down HMOX1-down|TNC-up HMOX1-down|ITGB4-up MT1X-down|SPP1-up TF-up|THBS1-down TF-up|TNC-up TF-up	COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 TF-up_7018|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 TF-up_7018|COL6A1-up_1291 HMOX1-down_3162|SPP1-up_6696 HMOX1-down_3162|THBS1-down_7057 HMOX1-down_3162|TNC-up_3371 HMOX1-down_3162|ITGB4-up_3691 MT1X-down_4501|SPP1-up_6696 TF-up_7018|THBS1-down_7057 TF-up_7018|TNC-up_3371 TF-up_7018
hsa04512	hsa05146	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	COL1A1-up ITGA10-down|COL1A1-up THBS1-down|COL1A2-up THBS1-down|COL6A1-up COL3A1-up|COL6A3-up COL3A1-up|COMP-up COL3A1-up|ITGB4-up COL3A1-up|ITGB8-up COL3A1-up|SPP1-up COL3A1-up|THBS1-down COL3A1-up|THBS2-up COL3A1-up|TNC-up COL3A1-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|SPP1-up IL1R2-down|ITGA10-down LAMA3-down|ITGB8-up TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 THBS1-down_7057|COL6A1-up_1291 COL3A1-up_1281|COL6A3-up_1293 COL3A1-up_1281|COMP-up_1311 COL3A1-up_1281|ITGB4-up_3691 COL3A1-up_1281|ITGB8-up_3696 COL3A1-up_1281|SPP1-up_6696 COL3A1-up_1281|THBS1-down_7057 COL3A1-up_1281|THBS2-up_7058 COL3A1-up_1281|TNC-up_3371 COL3A1-up_1281|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|SPP1-up_6696 IL1R2-down_7850|ITGA10-down_8515 LAMA3-down_3909|ITGB8-up_3696 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04512	hsa05152	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.001	COL1A1-up CD74-up|COL1A2-up CD74-up|THBS1-down CD74-up|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up TGFB3-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up|COMP-up TGFB3-up|ITGB8-up TGFB3-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|THBS1-down_7057 CD74-up_972|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 TGFB3-up_7043|ITGB8-up_3696 TGFB3-up_7043|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04512	hsa05160	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0.006	COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|ITGB4-up CLDN1-up|THBS1-down CLDN1-up|THBS2-up CLDN1-up|THBS1-down CLDN5-down|COL1A1-up LDLR-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|THBS1-down LDLR-down|TNC-up LDLR-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|ITGB4-up_3691 CLDN1-up_9076|THBS1-down_7057 CLDN1-up_9076|THBS2-up_7058 CLDN1-up_9076|THBS1-down_7057 CLDN5-down_7122|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|THBS1-down_7057 LDLR-down_3949|TNC-up_3371 LDLR-down_3949|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04512	hsa05166	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	COL1A1-up CCND1-up|COL1A2-up CCND1-up|ITGB4-up CCND1-up|LAMA3-down CCND1-up|SPP1-up CCND1-up|THBS1-down CCND1-up|THBS2-up CCND1-up|TNC-up CCND1-up|COL1A2-up CCND2-up|THBS1-down CCND2-up|TNC-up CCND2-up|COL1A1-up JUN-down|COL1A1-up MYB-up|COL1A1-up PDGFRA-down|COL1A1-up TGFB3-up|COL1A1-up VCAM1-up|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL1A2-up MYB-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL6A1-up JUN-down|COL6A1-up MYB-up|COL6A1-up PDGFRA-down|COL6A1-up TGFB3-up|COL6A3-up JUN-down|COL6A3-up PDGFRA-down|COL6A3-up TGFB3-up|COMP-up JUN-down|COMP-up TGFB3-up|ITGB8-up FZD5-down|SPP1-up IL1R2-down|ITGB4-up JUN-down|ITGB4-up MYB-up|ITGB4-up PDGFRA-down|ITGB4-up VCAM1-up|ITGB8-up TGFB3-up|LAMA3-down JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down VCAM1-up|SPP1-up MYB-up|THBS1-down MYB-up|THBS2-up MYB-up|TNC-up MYB-up|SPP1-up PDGFRA-down|THBS1-down PDGFRA-down|TNC-up PDGFRA-down|SPP1-up TGFB3-up|SPP1-up VCAM1-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down VCAM1-up|THBS2-up VCAM1-up|TNC-up VCAM1-up	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|ITGB4-up_3691 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|SPP1-up_6696 CCND1-up_595|THBS1-down_7057 CCND1-up_595|THBS2-up_7058 CCND1-up_595|TNC-up_3371 CCND1-up_595|COL1A2-up_1278 CCND2-up_894|THBS1-down_7057 CCND2-up_894|TNC-up_3371 CCND2-up_894|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MYB-up_4602|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MYB-up_4602|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MYB-up_4602|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 JUN-down_3725|COMP-up_1311 TGFB3-up_7043|ITGB8-up_3696 FZD5-down_7855|SPP1-up_6696 IL1R2-down_7850|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MYB-up_4602|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 VCAM1-up_7412|ITGB8-up_3696 TGFB3-up_7043|LAMA3-down_3909 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 VCAM1-up_7412|SPP1-up_6696 MYB-up_4602|THBS1-down_7057 MYB-up_4602|THBS2-up_7058 MYB-up_4602|TNC-up_3371 MYB-up_4602|SPP1-up_6696 PDGFRA-down_5156|THBS1-down_7057 PDGFRA-down_5156|TNC-up_3371 PDGFRA-down_5156|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 VCAM1-up_7412|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 VCAM1-up_7412|THBS2-up_7058 VCAM1-up_7412|TNC-up_3371 VCAM1-up_7412
hsa04512	hsa05168	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.02	COL1A1-up CD74-up|COL1A2-up CD74-up|THBS1-down CD74-up|COL1A1-up JUN-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL6A1-up JUN-down|COL6A3-up JUN-down|COMP-up JUN-down|ITGB4-up JUN-down|LAMA3-down JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|SPP1-up SOCS3-down|THBS1-down SOCS3-down|TNC-up SOCS3-down	COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|THBS1-down_7057 CD74-up_972|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL6A1-up_1291 JUN-down_3725|COL6A3-up_1293 JUN-down_3725|COMP-up_1311 JUN-down_3725|ITGB4-up_3691 JUN-down_3725|LAMA3-down_3909 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|SPP1-up_6696 SOCS3-down_9021|THBS1-down_7057 SOCS3-down_9021|TNC-up_3371 SOCS3-down_9021
hsa04512	hsa05200	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	COL1A1-up CCND1-up|COL1A2-up CCND1-up|ITGB4-up CCND1-up|SPP1-up CCND1-up|THBS1-down CCND1-up|THBS2-up CCND1-up|TNC-up CCND1-up|COL1A1-up CXCL12-up|COL1A1-up FIGF-down|COL1A1-up IGF1-up|COL1A1-up JUN-down|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up PDGFRA-down|COL1A1-up TCF7L2-up|COL1A1-up TGFB3-up|COL1A1-up ZBTB16-down|COL1A2-up CXCL12-up|COL1A2-up EDNRB-down|COL1A2-up FIGF-down|COL1A2-up IGF1-up|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL6A1-up JUN-down|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A1-up PDGFRA-down|COL6A1-up TGFB3-up|COL6A1-up ZBTB16-down|COL6A3-up JUN-down|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COL6A3-up PDGFRA-down|COL6A3-up TGFB3-up|COMP-up CXCL12-up|COMP-up IGF1-up|COMP-up JUN-down|COMP-up MMP1-up|COMP-up MMP2-up|COMP-up TGFB3-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|SPP1-up EDNRB-down|THBS1-down EDNRB-down|TNC-up EDNRB-down|SPP1-up FIGF-down|THBS1-down FIGF-down|THBS2-up FIGF-down|TNC-up FIGF-down|ITGB8-up FZD5-down|SPP1-up IGF1-up|THBS1-down IGF1-up|THBS2-up IGF1-up|TNC-up IGF1-up|ITGA10-down LAMA3-down|ITGB4-up JUN-down|ITGB4-up MMP1-up|ITGB4-up MMP2-up|ITGB4-up PDGFRA-down|ITGB8-up TGFB3-up|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|SPP1-up MMP1-up|THBS1-down MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|SPP1-up MMP2-up|THBS1-down MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|SPP1-up PDGFRA-down|THBS1-down PDGFRA-down|TNC-up PDGFRA-down|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|THBS1-down ZBTB16-down	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|ITGB4-up_3691 CCND1-up_595|SPP1-up_6696 CCND1-up_595|THBS1-down_7057 CCND1-up_595|THBS2-up_7058 CCND1-up_595|TNC-up_3371 CCND1-up_595|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TCF7L2-up_6934|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 EDNRB-down_1910|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 TGFB3-up_7043|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 IGF1-up_3479|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP1-up_4312|COMP-up_1311 MMP2-up_4313|COMP-up_1311 TGFB3-up_7043|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|SPP1-up_6696 EDNRB-down_1910|THBS1-down_7057 EDNRB-down_1910|TNC-up_3371 EDNRB-down_1910|SPP1-up_6696 FIGF-down_2277|THBS1-down_7057 FIGF-down_2277|THBS2-up_7058 FIGF-down_2277|TNC-up_3371 FIGF-down_2277|ITGB8-up_3696 FZD5-down_7855|SPP1-up_6696 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|THBS2-up_7058 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|ITGA10-down_8515 LAMA3-down_3909|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP1-up_4312|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 PDGFRA-down_5156|ITGB8-up_3696 TGFB3-up_7043|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|SPP1-up_6696 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|SPP1-up_6696 MMP2-up_4313|THBS1-down_7057 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|SPP1-up_6696 PDGFRA-down_5156|THBS1-down_7057 PDGFRA-down_5156|TNC-up_3371 PDGFRA-down_5156|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|THBS1-down_7057 ZBTB16-down_7704
hsa04512	hsa05202	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	COL1A2-up CCND2-up|THBS1-down CCND2-up|TNC-up CCND2-up|COL1A1-up FLT1-down|COL1A1-up IGF1-up|COL1A1-up PLAU-up|COL1A1-up PROM1-up|COL1A1-up SIX1-up|COL1A1-up ZBTB16-down|COL1A2-up FLT1-down|COL1A2-up IGF1-up|COL1A2-up PLAU-up|COL6A1-up ZBTB16-down|COL6A3-up PLAU-up|COMP-up IGF1-up|ITGB4-up FLT1-down|SPP1-up FLT1-down|THBS1-down FLT1-down|THBS2-up FLT1-down|TNC-up FLT1-down|SPP1-up IGF1-up|THBS1-down IGF1-up|THBS2-up IGF1-up|TNC-up IGF1-up|SPP1-up IL1R2-down|ITGB4-up PLAU-up|ITGB4-up PROM1-up|LAMA3-down PLAU-up|SPP1-up PLAU-up|THBS1-down PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up|THBS1-down PROM1-up|TNC-up PROM1-up|THBS1-down ZBTB16-down	COL1A2-up_1278 CCND2-up_894|THBS1-down_7057 CCND2-up_894|TNC-up_3371 CCND2-up_894|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 PROM1-up_8842|COL1A1-up_1277 SIX1-up_6495|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 PLAU-up_5328|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 IGF1-up_3479|ITGB4-up_3691 FLT1-down_2321|SPP1-up_6696 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|THBS2-up_7058 FLT1-down_2321|TNC-up_3371 FLT1-down_2321|SPP1-up_6696 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|THBS2-up_7058 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|SPP1-up_6696 IL1R2-down_7850|ITGB4-up_3691 PLAU-up_5328|ITGB4-up_3691 PROM1-up_8842|LAMA3-down_3909 PLAU-up_5328|SPP1-up_6696 PLAU-up_5328|THBS1-down_7057 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328|THBS1-down_7057 PROM1-up_8842|TNC-up_3371 PROM1-up_8842|THBS1-down_7057 ZBTB16-down_7704
hsa04512	hsa05205	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	ITGB4-up CAV2-down|ITGB8-up CAV2-down|LAMA3-down CAV2-down|COL1A1-up CCND1-up|COL1A2-up CCND1-up|ITGB4-up CCND1-up|LAMA3-down CCND1-up|SPP1-up CCND1-up|THBS2-up CCND1-up|TNC-up CCND1-up|COL1A1-up IGF1-up|COL1A1-up MMP2-up|COL1A1-up PLAU-up|COL1A2-up IGF1-up|COL1A2-up MMP2-up|COL1A2-up PLAU-up|COL6A1-up MMP2-up|COL6A3-up MMP2-up|COL6A3-up PLAU-up|COMP-up IGF1-up|COMP-up MMP2-up|ITGB4-up FLNC-up|ITGB8-up FLNC-up|TNC-up FLNC-up|ITGB8-up FZD5-down|LAMA3-down HBEGF-down|SPP1-up HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|SPP1-up IGF1-up|THBS2-up IGF1-up|TNC-up IGF1-up|ITGB4-up MMP2-up|ITGB4-up PLAU-up|LAMA3-down MMP2-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|SPP1-up MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up|SPP1-up PLAU-up|THBS2-up PLAU-up|TNC-up PLAU-up	ITGB4-up_3691 CAV2-down_858|ITGB8-up_3696 CAV2-down_858|LAMA3-down_3909 CAV2-down_858|COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|ITGB4-up_3691 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|SPP1-up_6696 CCND1-up_595|THBS2-up_7058 CCND1-up_595|TNC-up_3371 CCND1-up_595|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PLAU-up_5328|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PLAU-up_5328|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 PLAU-up_5328|COMP-up_1311 IGF1-up_3479|COMP-up_1311 MMP2-up_4313|ITGB4-up_3691 FLNC-up_2318|ITGB8-up_3696 FLNC-up_2318|TNC-up_3371 FLNC-up_2318|ITGB8-up_3696 FZD5-down_7855|LAMA3-down_3909 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|SPP1-up_6696 IGF1-up_3479|THBS2-up_7058 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|ITGB4-up_3691 MMP2-up_4313|ITGB4-up_3691 PLAU-up_5328|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|SPP1-up_6696 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|SPP1-up_6696 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|TNC-up_3371 PLAU-up_5328
hsa04512	hsa05206	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	COL1A1-up CCND1-up|COL1A2-up CCND1-up|ITGB4-up CCND1-up|LAMA3-down CCND1-up|SPP1-up CCND1-up|THBS2-up CCND1-up|COL1A2-up CCND2-up|COL1A1-up CYP24A1-up|COL1A1-up HMOX1-down|COL1A1-up MMP16-up|COL1A1-up PDGFRA-down|COL1A1-up PLAU-up|COL1A1-up SOX4-up|COL1A1-up TNC-up|COL1A2-up HMOX1-down|COL1A2-up MMP16-up|COL1A2-up PDGFRA-down|COL1A2-up PLAU-up|COL1A2-up TNC-up|COL6A1-up HMOX1-down|COL6A1-up MMP16-up|COL6A1-up PDGFRA-down|COL6A1-up TNC-up|COL6A3-up PDGFRA-down|COL6A3-up PLAU-up|COL6A3-up TNC-up|COMP-up MMP16-up|COMP-up TNC-up|SPP1-up CYP24A1-up|SPP1-up HMOX1-down|SPP1-up IRS2-down|ITGB4-up MCL1-down|ITGB4-up PDGFRA-down|ITGB4-up PLAU-up|ITGB4-up SERPINB5-up|ITGB4-up TNC-up|ITGB8-up MCL1-down|ITGB8-up TNC-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|LAMA3-down TNC-up|SPP1-up MCL1-down|THBS2-up MMP16-up|SPP1-up PDGFRA-down|SPP1-up PLAU-up|THBS2-up PLAU-up|SPP1-up SERPINB5-up|THBS2-up SERPINB5-up|SPP1-up TNC-up|SPP1-up TP63-up|THBS2-up TNC-up	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|ITGB4-up_3691 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|SPP1-up_6696 CCND1-up_595|THBS2-up_7058 CCND1-up_595|COL1A2-up_1278 CCND2-up_894|COL1A1-up_1277 CYP24A1-up_1591|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 MMP16-up_4325|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SOX4-up_6659|COL1A1-up_1277 TNC-up_3371|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 MMP16-up_4325|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 TNC-up_3371|COL6A1-up_1291 HMOX1-down_3162|COL6A1-up_1291 MMP16-up_4325|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 TNC-up_3371|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 PLAU-up_5328|COL6A3-up_1293 TNC-up_3371|COMP-up_1311 MMP16-up_4325|COMP-up_1311 TNC-up_3371|SPP1-up_6696 CYP24A1-up_1591|SPP1-up_6696 HMOX1-down_3162|SPP1-up_6696 IRS2-down_8660|ITGB4-up_3691 MCL1-down_4170|ITGB4-up_3691 PDGFRA-down_5156|ITGB4-up_3691 PLAU-up_5328|ITGB4-up_3691 SERPINB5-up_5268|ITGB4-up_3691 TNC-up_3371|ITGB8-up_3696 MCL1-down_4170|ITGB8-up_3696 TNC-up_3371|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|LAMA3-down_3909 TNC-up_3371|SPP1-up_6696 MCL1-down_4170|THBS2-up_7058 MMP16-up_4325|SPP1-up_6696 PDGFRA-down_5156|SPP1-up_6696 PLAU-up_5328|THBS2-up_7058 PLAU-up_5328|SPP1-up_6696 SERPINB5-up_5268|THBS2-up_7058 SERPINB5-up_5268|SPP1-up_6696 TNC-up_3371|SPP1-up_6696 TP63-up_8626|THBS2-up_7058 TNC-up_3371
hsa04512	hsa05219	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	COL1A1-up CCND1-up|COL1A2-up CCND1-up|ITGB4-up CCND1-up|LAMA3-down CCND1-up|SPP1-up CCND1-up|THBS2-up CCND1-up|TNC-up CCND1-up|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COMP-up MMP1-up|COMP-up MMP2-up|LAMA3-down HBEGF-down|SPP1-up HBEGF-down|THBS2-up HBEGF-down|TNC-up HBEGF-down|ITGB4-up MMP1-up|ITGB4-up MMP2-up|LAMA3-down MMP1-up|LAMA3-down MMP2-up|LAMA3-down THBS1-down|SPP1-up MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|SPP1-up MMP2-up|THBS2-up MMP2-up|TNC-up MMP2-up	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|ITGB4-up_3691 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|SPP1-up_6696 CCND1-up_595|THBS2-up_7058 CCND1-up_595|TNC-up_3371 CCND1-up_595|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COMP-up_1311 MMP1-up_4312|COMP-up_1311 MMP2-up_4313|LAMA3-down_3909 HBEGF-down_1839|SPP1-up_6696 HBEGF-down_1839|THBS2-up_7058 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|ITGB4-up_3691 MMP1-up_4312|ITGB4-up_3691 MMP2-up_4313|LAMA3-down_3909 MMP1-up_4312|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 THBS1-down_7057|SPP1-up_6696 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|SPP1-up_6696 MMP2-up_4313|THBS2-up_7058 MMP2-up_4313|TNC-up_3371 MMP2-up_4313
hsa04512	hsa05323	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	COL1A1-up CTSK-up|COL1A1-up CXCL12-up|COL1A1-up FLT1-down|COL1A1-up JUN-down|COL1A1-up MMP1-up|COL1A1-up TGFB3-up|COL1A2-up CTSK-up|COL1A2-up CXCL12-up|COL1A2-up FLT1-down|COL1A2-up JUN-down|COL1A2-up MMP1-up|COL1A2-up TGFB3-up|COL6A1-up CTSK-up|COL6A1-up JUN-down|COL6A1-up MMP1-up|COL6A1-up TGFB3-up|COL6A3-up CTSK-up|COL6A3-up JUN-down|COL6A3-up MMP1-up|COL6A3-up TGFB3-up|COMP-up CTSK-up|COMP-up CXCL12-up|COMP-up JUN-down|COMP-up MMP1-up|COMP-up TGFB3-up|SPP1-up CTSK-up|THBS1-down CTSK-up|THBS2-up CTSK-up|TNC-up CTSK-up|SPP1-up CXCL12-up|THBS1-down CXCL12-up|THBS2-up CXCL12-up|TNC-up CXCL12-up|ITGB4-up FLT1-down|SPP1-up FLT1-down|THBS1-down FLT1-down|THBS2-up FLT1-down|TNC-up FLT1-down|ITGB4-up JUN-down|ITGB4-up MMP1-up|ITGB8-up TGFB3-up|LAMA3-down JUN-down|SPP1-up JUN-down|THBS1-down JUN-down|THBS2-up JUN-down|TNC-up JUN-down|LAMA3-down MMP1-up|SPP1-up MMP1-up|THBS1-down MMP1-up|THBS2-up MMP1-up|TNC-up MMP1-up|SPP1-up TGFB3-up|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up	COL1A1-up_1277 CTSK-up_1513|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 CTSK-up_1513|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 TGFB3-up_7043|COL6A1-up_1291 CTSK-up_1513|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 CTSK-up_1513|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 TGFB3-up_7043|COMP-up_1311 CTSK-up_1513|COMP-up_1311 CXCL12-up_6387|COMP-up_1311 JUN-down_3725|COMP-up_1311 MMP1-up_4312|COMP-up_1311 TGFB3-up_7043|SPP1-up_6696 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|THBS2-up_7058 CTSK-up_1513|TNC-up_3371 CTSK-up_1513|SPP1-up_6696 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|THBS2-up_7058 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|ITGB4-up_3691 FLT1-down_2321|SPP1-up_6696 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|THBS2-up_7058 FLT1-down_2321|TNC-up_3371 FLT1-down_2321|ITGB4-up_3691 JUN-down_3725|ITGB4-up_3691 MMP1-up_4312|ITGB8-up_3696 TGFB3-up_7043|LAMA3-down_3909 JUN-down_3725|SPP1-up_6696 JUN-down_3725|THBS1-down_7057 JUN-down_3725|THBS2-up_7058 JUN-down_3725|TNC-up_3371 JUN-down_3725|LAMA3-down_3909 MMP1-up_4312|SPP1-up_6696 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|THBS2-up_7058 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|SPP1-up_6696 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043
hsa04512	hsa05410	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	COL1A1-up IGF1-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COMP-up IGF1-up|COMP-up ITGB4-up|COMP-up ITGB8-up|COMP-up TGFB3-up|SPP1-up IGF1-up|THBS1-down IGF1-up|THBS2-up IGF1-up|TNC-up IGF1-up|ITGB4-up LAMA3-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up THBS1-down|SPP1-up TGFB3-up|SPP1-up TTN-down|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|TNC-up TNNC1-down	COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COMP-up_1311 IGF1-up_3479|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|COMP-up_1311 TGFB3-up_7043|SPP1-up_6696 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|THBS2-up_7058 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa04512	hsa05412	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	COL1A1-up CDH2-up|COL1A2-up CDH2-up|COMP-up CDH2-up|SPP1-up CDH2-up|THBS1-down CDH2-up|THBS2-up CDH2-up|TNC-up CDH2-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TCF7L2-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COMP-up ITGB4-up|COMP-up ITGB8-up|ITGB4-up LAMA3-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up THBS1-down	COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COMP-up_1311 CDH2-up_1000|SPP1-up_6696 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|THBS2-up_7058 CDH2-up_1000|TNC-up_3371 CDH2-up_1000|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TCF7L2-up_6934|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057
hsa04512	hsa05414	ECM-receptor interaction - Homo sapiens (human)	ITGA10,LAMA3,THBS1,AGRN,COL1A1,COL1A2,COL6A1,COL6A3,COMP,ITGB4,ITGB8,SPP1,THBS2,TNC	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	SPP1-up ADRB1-down|COL1A1-up IGF1-up|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up PLN-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COMP-up IGF1-up|COMP-up ITGB4-up|COMP-up ITGB8-up|COMP-up PLN-up|COMP-up TGFB3-up|SPP1-up IGF1-up|THBS1-down IGF1-up|THBS2-up IGF1-up|TNC-up IGF1-up|ITGB4-up LAMA3-down|ITGB4-up THBS1-down|ITGB8-up LAMA3-down|ITGB8-up THBS1-down|SPP1-up TGFB3-up|SPP1-up TTN-down|THBS1-down TGFB3-up|THBS2-up TGFB3-up|TNC-up TGFB3-up|TNC-up TNNC1-down	SPP1-up_6696 ADRB1-down_153|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 PLN-up_5350|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COMP-up_1311 IGF1-up_3479|COMP-up_1311 ITGB4-up_3691|COMP-up_1311 ITGB8-up_3696|COMP-up_1311 PLN-up_5350|COMP-up_1311 TGFB3-up_7043|SPP1-up_6696 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|THBS2-up_7058 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|ITGB4-up_3691 LAMA3-down_3909|ITGB4-up_3691 THBS1-down_7057|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 THBS1-down_7057|SPP1-up_6696 TGFB3-up_7043|SPP1-up_6696 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043|THBS2-up_7058 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa04514	hsa04550	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	0	CD274-down IGF1-up|CDH2-up FZD5-down|CDH2-up IGF1-up|CDH2-up JAK1-down|CDH2-up SOX2-up|CDH3-up SOX2-up|CLDN5-down IGF1-up|ITGB8-up FZD5-down|NCAM1-up IGF1-up|SELL-down IGF1-up|VCAM1-up IGF1-up|NCAM1-up JAK1-down|SELL-down JAK1-down|VCAM1-up JAK1-down|VCAM1-up LIFR-down|NCAM1-up SOX2-up	CD274-down_29126 IGF1-up_3479|CDH2-up_1000 FZD5-down_7855|CDH2-up_1000 IGF1-up_3479|CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 SOX2-up_6657|CDH3-up_1001 SOX2-up_6657|CLDN5-down_7122 IGF1-up_3479|ITGB8-up_3696 FZD5-down_7855|NCAM1-up_4684 IGF1-up_3479|SELL-down_6402 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|VCAM1-up_7412 LIFR-down_3977|NCAM1-up_4684 SOX2-up_6657
hsa04514	hsa04610	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.003	CDH2-up PLAU-up|CDH2-up SERPINE1-down|CDH3-up PLAU-up|SELL-down CFH-up|CLDN1-up PLAU-up|CLDN5-down SERPINE1-down|SELL-down F3-down|VCAM1-up F3-down|NCAM1-up SERPINE1-down|VCAM1-up PLAU-up|SELL-down SERPINE1-down|VCAM1-up SERPINE1-down|VCAM1-up TFPI-down	CDH2-up_1000 PLAU-up_5328|CDH2-up_1000 SERPINE1-down_5054|CDH3-up_1001 PLAU-up_5328|SELL-down_6402 CFH-up_3075|CLDN1-up_9076 PLAU-up_5328|CLDN5-down_7122 SERPINE1-down_5054|SELL-down_6402 F3-down_2152|VCAM1-up_7412 F3-down_2152|NCAM1-up_4684 SERPINE1-down_5054|VCAM1-up_7412 PLAU-up_5328|SELL-down_6402 SERPINE1-down_5054|VCAM1-up_7412 SERPINE1-down_5054|VCAM1-up_7412 TFPI-down_7035
hsa04514	hsa04630	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0	CD274-down CCND1-up|CDH2-up CCND1-up|CDH3-up CCND1-up|NCAM1-up CCND1-up|VCAM1-up CCND1-up|CDH2-up CCND2-up|NCAM1-up CCND2-up|CD274-down SOCS3-down|CDH2-up JAK1-down|CDH2-up MCL1-down|CDH2-up SOCS3-down|NCAM1-up CSF3R-down|ITGB8-up MCL1-down|NCAM1-up JAK1-down|SELL-down JAK1-down|VCAM1-up JAK1-down|VCAM1-up LIFR-down|NCAM1-up MCL1-down|SELL-down MCL1-down|VCAM1-up MCL1-down|NCAM1-up SOCS3-down|SELL-down SOCS3-down|VCAM1-up SOCS3-down	CD274-down_29126 CCND1-up_595|CDH2-up_1000 CCND1-up_595|CDH3-up_1001 CCND1-up_595|NCAM1-up_4684 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CDH2-up_1000 CCND2-up_894|NCAM1-up_4684 CCND2-up_894|CD274-down_29126 SOCS3-down_9021|CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 MCL1-down_4170|CDH2-up_1000 SOCS3-down_9021|NCAM1-up_4684 CSF3R-down_1441|ITGB8-up_3696 MCL1-down_4170|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|VCAM1-up_7412 LIFR-down_3977|NCAM1-up_4684 MCL1-down_4170|SELL-down_6402 MCL1-down_4170|VCAM1-up_7412 MCL1-down_4170|NCAM1-up_4684 SOCS3-down_9021|SELL-down_6402 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04514	hsa04668	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.001	CD274-down SOCS3-down|CD274-down VCAM1-up|CDH2-up IL18R1-down|CDH2-up JUN-down|CDH2-up MAP3K8-down|CDH2-up SOCS3-down|CDH2-up VCAM1-up|CLDN5-down JUN-down|CLDN5-down VCAM1-up|SELL-down CXCL2-down|SELL-down CXCL3-down|NCAM1-up IL18R1-down|NCAM1-up JUN-down|SELL-down JUN-down|NCAM1-up MAP3K8-down|NCAM1-up SOCS3-down|NCAM1-up VCAM1-up|SELL-down SOCS3-down|SELL-down VCAM1-up	CD274-down_29126 SOCS3-down_9021|CD274-down_29126 VCAM1-up_7412|CDH2-up_1000 IL18R1-down_8809|CDH2-up_1000 JUN-down_3725|CDH2-up_1000 MAP3K8-down_1326|CDH2-up_1000 SOCS3-down_9021|CDH2-up_1000 VCAM1-up_7412|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 VCAM1-up_7412|SELL-down_6402 CXCL2-down_2920|SELL-down_6402 CXCL3-down_2921|NCAM1-up_4684 IL18R1-down_8809|NCAM1-up_4684 JUN-down_3725|SELL-down_6402 JUN-down_3725|NCAM1-up_4684 MAP3K8-down_1326|NCAM1-up_4684 SOCS3-down_9021|NCAM1-up_4684 VCAM1-up_7412|SELL-down_6402 SOCS3-down_9021|SELL-down_6402 VCAM1-up_7412
hsa04514	hsa04670	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CD274-down CXCL12-up|CD274-down VCAM1-up|CDH2-up CLDN1-up|CDH2-up CXCL12-up|CDH2-up MMP2-up|CDH2-up VCAM1-up|CDH3-up CLDN1-up|NCAM1-up CXCL12-up|SELL-down CXCL12-up|VTCN1-up CXCL12-up|NCAM1-up MMP2-up|SELL-down MMP2-up|NCAM1-up THY1-up|NCAM1-up VCAM1-up|SELL-down THY1-up|SELL-down VCAM1-up	CD274-down_29126 CXCL12-up_6387|CD274-down_29126 VCAM1-up_7412|CDH2-up_1000 CLDN1-up_9076|CDH2-up_1000 CXCL12-up_6387|CDH2-up_1000 MMP2-up_4313|CDH2-up_1000 VCAM1-up_7412|CDH3-up_1001 CLDN1-up_9076|NCAM1-up_4684 CXCL12-up_6387|SELL-down_6402 CXCL12-up_6387|VTCN1-up_79679 CXCL12-up_6387|NCAM1-up_4684 MMP2-up_4313|SELL-down_6402 MMP2-up_4313|NCAM1-up_4684 THY1-up_7070|NCAM1-up_4684 VCAM1-up_7412|SELL-down_6402 THY1-up_7070|SELL-down_6402 VCAM1-up_7412
hsa04514	hsa04933	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	CD274-down CCND1-up|CDH2-up CCND1-up|CDH3-up CCND1-up|NCAM1-up CCND1-up|CD274-down VCAM1-up|CDH2-up COL1A1-up|CDH2-up COL1A2-up|CDH2-up COL3A1-up|CDH2-up FIGF-down|CDH2-up JUN-down|CDH2-up MMP2-up|CDH2-up SERPINE1-down|CDH2-up TGFB3-up|CDH2-up VCAM1-up|CLDN1-up COL1A1-up|CLDN1-up COL1A2-up|CLDN1-up COL3A1-up|CLDN1-up MMP2-up|CLDN5-down FIGF-down|CLDN5-down JUN-down|CLDN5-down MMP2-up|CLDN5-down SERPINE1-down|CLDN5-down VCAM1-up|ITGB8-up COL1A1-up|ITGB8-up COL1A2-up|NCAM1-up COL1A2-up|ITGB8-up COL3A1-up|SELL-down F3-down|ITGB8-up TGFB3-up|NCAM1-up JUN-down|SELL-down JUN-down|NCAM1-up MMP2-up|SELL-down MMP2-up|NCAM1-up SERPINE1-down|NCAM1-up TGFB3-up|NCAM1-up VCAM1-up|SELL-down SERPINE1-down|SELL-down VCAM1-up	CD274-down_29126 CCND1-up_595|CDH2-up_1000 CCND1-up_595|CDH3-up_1001 CCND1-up_595|NCAM1-up_4684 CCND1-up_595|CD274-down_29126 VCAM1-up_7412|CDH2-up_1000 COL1A1-up_1277|CDH2-up_1000 COL1A2-up_1278|CDH2-up_1000 COL3A1-up_1281|CDH2-up_1000 FIGF-down_2277|CDH2-up_1000 JUN-down_3725|CDH2-up_1000 MMP2-up_4313|CDH2-up_1000 SERPINE1-down_5054|CDH2-up_1000 TGFB3-up_7043|CDH2-up_1000 VCAM1-up_7412|CLDN1-up_9076 COL1A1-up_1277|CLDN1-up_9076 COL1A2-up_1278|CLDN1-up_9076 COL3A1-up_1281|CLDN1-up_9076 MMP2-up_4313|CLDN5-down_7122 FIGF-down_2277|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 SERPINE1-down_5054|CLDN5-down_7122 VCAM1-up_7412|ITGB8-up_3696 COL1A1-up_1277|ITGB8-up_3696 COL1A2-up_1278|NCAM1-up_4684 COL1A2-up_1278|ITGB8-up_3696 COL3A1-up_1281|SELL-down_6402 F3-down_2152|ITGB8-up_3696 TGFB3-up_7043|NCAM1-up_4684 JUN-down_3725|SELL-down_6402 JUN-down_3725|NCAM1-up_4684 MMP2-up_4313|SELL-down_6402 MMP2-up_4313|NCAM1-up_4684 SERPINE1-down_5054|NCAM1-up_4684 TGFB3-up_7043|NCAM1-up_4684 VCAM1-up_7412|SELL-down_6402 SERPINE1-down_5054|SELL-down_6402 VCAM1-up_7412
hsa04514	hsa04974	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CDH2-up COL17A1-up|CDH2-up COL18A1-up|CDH2-up COL1A1-up|CDH2-up COL1A2-up|CDH2-up COL3A1-up|CDH2-up COL5A1-up|CDH2-up MME-down|CDH2-up PRSS1-up|CLDN1-up COL17A1-up|CLDN1-up COL1A1-up|CLDN1-up COL1A2-up|CLDN1-up COL3A1-up|ITGB8-up COL14A1-up|VCAM1-up COL18A1-up|ITGB8-up COL1A1-up|VCAM1-up COL1A1-up|ITGB8-up COL1A2-up|NCAM1-up COL1A2-up|ITGB8-up COL3A1-up|ITGB8-up COL5A1-up|ITGB8-up COL5A2-up|ITGB8-up COL6A1-up|ITGB8-up COL6A3-up|NCAM1-up MME-down|SELL-down MME-down|VCAM1-up MME-down	CDH2-up_1000 COL17A1-up_1308|CDH2-up_1000 COL18A1-up_80781|CDH2-up_1000 COL1A1-up_1277|CDH2-up_1000 COL1A2-up_1278|CDH2-up_1000 COL3A1-up_1281|CDH2-up_1000 COL5A1-up_1289|CDH2-up_1000 MME-down_4311|CDH2-up_1000 PRSS1-up_5644|CLDN1-up_9076 COL17A1-up_1308|CLDN1-up_9076 COL1A1-up_1277|CLDN1-up_9076 COL1A2-up_1278|CLDN1-up_9076 COL3A1-up_1281|ITGB8-up_3696 COL14A1-up_7373|VCAM1-up_7412 COL18A1-up_80781|ITGB8-up_3696 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|ITGB8-up_3696 COL1A2-up_1278|NCAM1-up_4684 COL1A2-up_1278|ITGB8-up_3696 COL3A1-up_1281|ITGB8-up_3696 COL5A1-up_1289|ITGB8-up_3696 COL5A2-up_1290|ITGB8-up_3696 COL6A1-up_1291|ITGB8-up_3696 COL6A3-up_1293|NCAM1-up_4684 MME-down_4311|SELL-down_6402 MME-down_4311|VCAM1-up_7412 MME-down_4311
hsa04514	hsa04978	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.007	CD274-down HMOX1-down|CDH2-up TF-up|CLDN5-down HMOX1-down|CLDN5-down TF-up|SELL-down HMOX1-down|VCAM1-up HMOX1-down|NCAM1-up MT2A-down|VCAM1-up MT2A-down|NCAM1-up TF-up|SELL-down TF-up|VCAM1-up TF-up	CD274-down_29126 HMOX1-down_3162|CDH2-up_1000 TF-up_7018|CLDN5-down_7122 HMOX1-down_3162|CLDN5-down_7122 TF-up_7018|SELL-down_6402 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|NCAM1-up_4684 MT2A-down_4502|VCAM1-up_7412 MT2A-down_4502|NCAM1-up_4684 TF-up_7018|SELL-down_6402 TF-up_7018|VCAM1-up_7412 TF-up_7018
hsa04514	hsa05145	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.003	CDH2-up JAK1-down|CDH2-up TGFB3-up|CDH3-up LAMA3-down|CLDN1-up LDLR-down|ITGB8-up LAMA3-down|ITGB8-up TGFB3-up|NCAM1-up JAK1-down|SELL-down JAK1-down|VCAM1-up JAK1-down|VCAM1-up LAMA3-down|NCAM1-up LDLR-down|VCAM1-up LDLR-down|NCAM1-up TGFB3-up|VCAM1-up TGFB3-up	CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 TGFB3-up_7043|CDH3-up_1001 LAMA3-down_3909|CLDN1-up_9076 LDLR-down_3949|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 TGFB3-up_7043|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|VCAM1-up_7412 LAMA3-down_3909|NCAM1-up_4684 LDLR-down_3949|VCAM1-up_7412 LDLR-down_3949|NCAM1-up_4684 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04514	hsa05146	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CDH2-up COL1A1-up|CDH2-up COL1A2-up|CDH2-up COL3A1-up|CDH2-up TGFB3-up|CDH3-up LAMA3-down|CLDN1-up COL1A1-up|CLDN1-up COL1A2-up|CLDN1-up COL3A1-up|ITGB8-up COL1A1-up|VCAM1-up COL1A1-up|ITGB8-up COL1A2-up|NCAM1-up COL1A2-up|ITGB8-up COL3A1-up|ITGB8-up LAMA3-down|ITGB8-up TGFB3-up|VCAM1-up LAMA3-down|NCAM1-up TGFB3-up|SELL-down SERPINB3-up|VCAM1-up TGFB3-up	CDH2-up_1000 COL1A1-up_1277|CDH2-up_1000 COL1A2-up_1278|CDH2-up_1000 COL3A1-up_1281|CDH2-up_1000 TGFB3-up_7043|CDH3-up_1001 LAMA3-down_3909|CLDN1-up_9076 COL1A1-up_1277|CLDN1-up_9076 COL1A2-up_1278|CLDN1-up_9076 COL3A1-up_1281|ITGB8-up_3696 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|ITGB8-up_3696 COL1A2-up_1278|NCAM1-up_4684 COL1A2-up_1278|ITGB8-up_3696 COL3A1-up_1281|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 TGFB3-up_7043|VCAM1-up_7412 LAMA3-down_3909|NCAM1-up_4684 TGFB3-up_7043|SELL-down_6402 SERPINB3-up_6317|VCAM1-up_7412 TGFB3-up_7043
hsa04514	hsa05152	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.001	CDH2-up CD74-up|NCAM1-up CD74-up|SELL-down CD74-up|VCAM1-up CD74-up|CDH2-up JAK1-down|CDH2-up TGFB3-up|ITGB8-up TGFB3-up|NCAM1-up JAK1-down|SELL-down JAK1-down|VCAM1-up JAK1-down|NCAM1-up TGFB3-up|VCAM1-up TGFB3-up	CDH2-up_1000 CD74-up_972|NCAM1-up_4684 CD74-up_972|SELL-down_6402 CD74-up_972|VCAM1-up_7412 CD74-up_972|CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 TGFB3-up_7043|ITGB8-up_3696 TGFB3-up_7043|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|NCAM1-up_4684 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04514	hsa05164	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0.035	CD274-down SOCS3-down|CDH2-up JAK1-down|CDH2-up JUN-down|CDH2-up PRSS1-up|CDH2-up SOCS3-down|CDH3-up TMPRSS4-up|CLDN5-down JUN-down|NCAM1-up JAK1-down|SELL-down JAK1-down|VCAM1-up JAK1-down|NCAM1-up JUN-down|SELL-down JUN-down|VCAM1-up JUN-down|NCAM1-up SOCS3-down|SELL-down SOCS3-down|VCAM1-up SOCS3-down	CD274-down_29126 SOCS3-down_9021|CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 JUN-down_3725|CDH2-up_1000 PRSS1-up_5644|CDH2-up_1000 SOCS3-down_9021|CDH3-up_1001 TMPRSS4-up_56649|CLDN5-down_7122 JUN-down_3725|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|NCAM1-up_4684 JUN-down_3725|SELL-down_6402 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|NCAM1-up_4684 SOCS3-down_9021|SELL-down_6402 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04514	hsa05166	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.003	CD274-down CCND1-up|CDH2-up CCND1-up|CDH3-up CCND1-up|NCAM1-up CCND1-up|CDH2-up CCND2-up|NCAM1-up CCND2-up|CD274-down PDGFRA-down|CD274-down VCAM1-up|CDH2-up FZD5-down|CDH2-up JAK1-down|CDH2-up JUN-down|CDH2-up MYB-up|CDH2-up PDGFRA-down|CDH2-up TGFB3-up|CDH2-up VCAM1-up|CLDN1-up MYB-up|CLDN5-down JUN-down|CLDN5-down MYB-up|CLDN5-down VCAM1-up|ITGB8-up FZD5-down|ITGB8-up TGFB3-up|NCAM1-up JAK1-down|SELL-down JAK1-down|NCAM1-up JUN-down|SELL-down JUN-down|NCAM1-up MYB-up|NCAM1-up PDGFRA-down|NCAM1-up TGFB3-up|NCAM1-up VCAM1-up|SELL-down VCAM1-up	CD274-down_29126 CCND1-up_595|CDH2-up_1000 CCND1-up_595|CDH3-up_1001 CCND1-up_595|NCAM1-up_4684 CCND1-up_595|CDH2-up_1000 CCND2-up_894|NCAM1-up_4684 CCND2-up_894|CD274-down_29126 PDGFRA-down_5156|CD274-down_29126 VCAM1-up_7412|CDH2-up_1000 FZD5-down_7855|CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 JUN-down_3725|CDH2-up_1000 MYB-up_4602|CDH2-up_1000 PDGFRA-down_5156|CDH2-up_1000 TGFB3-up_7043|CDH2-up_1000 VCAM1-up_7412|CLDN1-up_9076 MYB-up_4602|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MYB-up_4602|CLDN5-down_7122 VCAM1-up_7412|ITGB8-up_3696 FZD5-down_7855|ITGB8-up_3696 TGFB3-up_7043|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|NCAM1-up_4684 JUN-down_3725|SELL-down_6402 JUN-down_3725|NCAM1-up_4684 MYB-up_4602|NCAM1-up_4684 PDGFRA-down_5156|NCAM1-up_4684 TGFB3-up_7043|NCAM1-up_4684 VCAM1-up_7412|SELL-down_6402 VCAM1-up_7412
hsa04514	hsa05168	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.001	CD274-down SOCS3-down|CDH2-up CD74-up|NCAM1-up CD74-up|SELL-down CD74-up|VCAM1-up CD74-up|CDH2-up JAK1-down|CDH2-up JUN-down|CDH2-up SOCS3-down|CLDN5-down JUN-down|NCAM1-up JAK1-down|SELL-down JAK1-down|VCAM1-up JAK1-down|NCAM1-up JUN-down|SELL-down JUN-down|VCAM1-up JUN-down|NCAM1-up SOCS3-down|SELL-down SOCS3-down|VCAM1-up SOCS3-down	CD274-down_29126 SOCS3-down_9021|CDH2-up_1000 CD74-up_972|NCAM1-up_4684 CD74-up_972|SELL-down_6402 CD74-up_972|VCAM1-up_7412 CD74-up_972|CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 JUN-down_3725|CDH2-up_1000 SOCS3-down_9021|CLDN5-down_7122 JUN-down_3725|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|NCAM1-up_4684 JUN-down_3725|SELL-down_6402 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|NCAM1-up_4684 SOCS3-down_9021|SELL-down_6402 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04514	hsa05200	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	CD274-down CCND1-up|CDH2-up CCND1-up|CDH3-up CCND1-up|NCAM1-up CCND1-up|VCAM1-up CCND1-up|CD274-down CXCL12-up|CD274-down IGF1-up|CD274-down PDGFRA-down|CDH2-up CXCL12-up|CDH2-up EDNRB-down|CDH2-up FIGF-down|CDH2-up FZD5-down|CDH2-up IGF1-up|CDH2-up JAK1-down|CDH2-up JUN-down|CDH2-up MMP1-up|CDH2-up MMP2-up|CDH2-up PDGFRA-down|CDH2-up TCF7L2-up|CDH2-up TGFB3-up|CDH3-up LAMA3-down|CLDN1-up EDNRB-down|CLDN1-up MMP1-up|CLDN1-up MMP2-up|CLDN1-up TCF7L2-up|CLDN5-down CXCL12-up|CLDN5-down EDNRB-down|CLDN5-down FIGF-down|CLDN5-down IGF1-up|CLDN5-down JUN-down|CLDN5-down MMP1-up|CLDN5-down MMP2-up|CLDN5-down TCF7L2-up|NCAM1-up CSF3R-down|NCAM1-up CXCL12-up|SELL-down CXCL12-up|VCAM1-up CXCL12-up|VTCN1-up CXCL12-up|NCAM1-up EDNRB-down|VCAM1-up EDNRB-down|NFASC-up FGF14-up|VCAM1-up FIGF-down|ITGB8-up FZD5-down|NCAM1-up IGF1-up|SELL-down IGF1-up|VCAM1-up IGF1-up|ITGB8-up LAMA3-down|ITGB8-up TGFB3-up|NCAM1-up JAK1-down|SELL-down JAK1-down|VCAM1-up JAK1-down|NCAM1-up JUN-down|SELL-down JUN-down|VCAM1-up JUN-down|VCAM1-up LAMA3-down|NCAM1-up MMP1-up|VCAM1-up MMP1-up|NCAM1-up MMP2-up|SELL-down MMP2-up|VCAM1-up MMP2-up|NCAM1-up PDGFRA-down|NCAM1-up TGFB3-up|NCAM1-up ZBTB16-down|VCAM1-up PDGFRA-down|SELL-down ZBTB16-down|VCAM1-up TGFB3-up	CD274-down_29126 CCND1-up_595|CDH2-up_1000 CCND1-up_595|CDH3-up_1001 CCND1-up_595|NCAM1-up_4684 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CD274-down_29126 CXCL12-up_6387|CD274-down_29126 IGF1-up_3479|CD274-down_29126 PDGFRA-down_5156|CDH2-up_1000 CXCL12-up_6387|CDH2-up_1000 EDNRB-down_1910|CDH2-up_1000 FIGF-down_2277|CDH2-up_1000 FZD5-down_7855|CDH2-up_1000 IGF1-up_3479|CDH2-up_1000 JAK1-down_3716|CDH2-up_1000 JUN-down_3725|CDH2-up_1000 MMP1-up_4312|CDH2-up_1000 MMP2-up_4313|CDH2-up_1000 PDGFRA-down_5156|CDH2-up_1000 TCF7L2-up_6934|CDH2-up_1000 TGFB3-up_7043|CDH3-up_1001 LAMA3-down_3909|CLDN1-up_9076 EDNRB-down_1910|CLDN1-up_9076 MMP1-up_4312|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 TCF7L2-up_6934|CLDN5-down_7122 CXCL12-up_6387|CLDN5-down_7122 EDNRB-down_1910|CLDN5-down_7122 FIGF-down_2277|CLDN5-down_7122 IGF1-up_3479|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MMP1-up_4312|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 TCF7L2-up_6934|NCAM1-up_4684 CSF3R-down_1441|NCAM1-up_4684 CXCL12-up_6387|SELL-down_6402 CXCL12-up_6387|VCAM1-up_7412 CXCL12-up_6387|VTCN1-up_79679 CXCL12-up_6387|NCAM1-up_4684 EDNRB-down_1910|VCAM1-up_7412 EDNRB-down_1910|NFASC-up_23114 FGF14-up_2259|VCAM1-up_7412 FIGF-down_2277|ITGB8-up_3696 FZD5-down_7855|NCAM1-up_4684 IGF1-up_3479|SELL-down_6402 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|ITGB8-up_3696 LAMA3-down_3909|ITGB8-up_3696 TGFB3-up_7043|NCAM1-up_4684 JAK1-down_3716|SELL-down_6402 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|NCAM1-up_4684 JUN-down_3725|SELL-down_6402 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|VCAM1-up_7412 LAMA3-down_3909|NCAM1-up_4684 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|NCAM1-up_4684 MMP2-up_4313|SELL-down_6402 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|NCAM1-up_4684 PDGFRA-down_5156|NCAM1-up_4684 TGFB3-up_7043|NCAM1-up_4684 ZBTB16-down_7704|VCAM1-up_7412 PDGFRA-down_5156|SELL-down_6402 ZBTB16-down_7704|VCAM1-up_7412 TGFB3-up_7043
hsa04514	hsa05202	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	CDH2-up CCND2-up|NCAM1-up CCND2-up|CD274-down IGF1-up|CDH2-up FLT1-down|CDH2-up IGF1-up|CDH2-up PLAU-up|CDH2-up PROM1-up|CDH2-up SIX1-up|CDH3-up PLAU-up|CLDN1-up PLAU-up|CLDN5-down FLT1-down|CLDN5-down IGF1-up|NCAM1-up FLT1-down|SELL-down FLT1-down|VCAM1-up FLT1-down|NCAM1-up IGF1-up|SELL-down IGF1-up|VCAM1-up IGF1-up|NCAM1-up PROM1-up|NCAM1-up ZBTB16-down|VCAM1-up PLAU-up|SELL-down PROM1-up|VCAM1-up PROM1-up|VTCN1-up PROM1-up|SELL-down ZBTB16-down	CDH2-up_1000 CCND2-up_894|NCAM1-up_4684 CCND2-up_894|CD274-down_29126 IGF1-up_3479|CDH2-up_1000 FLT1-down_2321|CDH2-up_1000 IGF1-up_3479|CDH2-up_1000 PLAU-up_5328|CDH2-up_1000 PROM1-up_8842|CDH2-up_1000 SIX1-up_6495|CDH3-up_1001 PLAU-up_5328|CLDN1-up_9076 PLAU-up_5328|CLDN5-down_7122 FLT1-down_2321|CLDN5-down_7122 IGF1-up_3479|NCAM1-up_4684 FLT1-down_2321|SELL-down_6402 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|NCAM1-up_4684 IGF1-up_3479|SELL-down_6402 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|NCAM1-up_4684 PROM1-up_8842|NCAM1-up_4684 ZBTB16-down_7704|VCAM1-up_7412 PLAU-up_5328|SELL-down_6402 PROM1-up_8842|VCAM1-up_7412 PROM1-up_8842|VTCN1-up_79679 PROM1-up_8842|SELL-down_6402 ZBTB16-down_7704
hsa04514	hsa05205	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	CDH2-up ANK2-up|CDH3-up ANK2-up|NFASC-up ANK2-up|CDH2-up CAV2-down|ITGB8-up CAV2-down|CD274-down CCND1-up|CDH2-up CCND1-up|CDH3-up CCND1-up|NCAM1-up CCND1-up|VCAM1-up CCND1-up|CD274-down IGF1-up|CDH2-up FZD5-down|CDH2-up HBEGF-down|CDH2-up IGF1-up|CDH2-up MMP2-up|CDH2-up PLAU-up|CDH2-up THBS1-down|CDH3-up PLAU-up|CLDN1-up MMP2-up|CLDN1-up PLAU-up|CLDN1-up THBS1-down|CLDN5-down IGF1-up|CLDN5-down MMP2-up|CLDN5-down THBS1-down|ITGB8-up FLNC-up|VCAM1-up FLNC-up|ITGB8-up FZD5-down|SELL-down HBEGF-down|VCAM1-up HBEGF-down|NCAM1-up IGF1-up|SELL-down IGF1-up|VCAM1-up IGF1-up|ITGB8-up THBS1-down|NCAM1-up MMP2-up|SELL-down MMP2-up|VCAM1-up MMP2-up|NCAM1-up THBS1-down|VCAM1-up PLAU-up|VCAM1-up THBS1-down	CDH2-up_1000 ANK2-up_287|CDH3-up_1001 ANK2-up_287|NFASC-up_23114 ANK2-up_287|CDH2-up_1000 CAV2-down_858|ITGB8-up_3696 CAV2-down_858|CD274-down_29126 CCND1-up_595|CDH2-up_1000 CCND1-up_595|CDH3-up_1001 CCND1-up_595|NCAM1-up_4684 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CD274-down_29126 IGF1-up_3479|CDH2-up_1000 FZD5-down_7855|CDH2-up_1000 HBEGF-down_1839|CDH2-up_1000 IGF1-up_3479|CDH2-up_1000 MMP2-up_4313|CDH2-up_1000 PLAU-up_5328|CDH2-up_1000 THBS1-down_7057|CDH3-up_1001 PLAU-up_5328|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 PLAU-up_5328|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 IGF1-up_3479|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 THBS1-down_7057|ITGB8-up_3696 FLNC-up_2318|VCAM1-up_7412 FLNC-up_2318|ITGB8-up_3696 FZD5-down_7855|SELL-down_6402 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|NCAM1-up_4684 IGF1-up_3479|SELL-down_6402 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|ITGB8-up_3696 THBS1-down_7057|NCAM1-up_4684 MMP2-up_4313|SELL-down_6402 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|NCAM1-up_4684 THBS1-down_7057|VCAM1-up_7412 PLAU-up_5328|VCAM1-up_7412 THBS1-down_7057
hsa04514	hsa05206	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CD274-down CCND1-up|CDH2-up CCND1-up|CDH3-up CCND1-up|NCAM1-up CCND1-up|VCAM1-up CCND1-up|CDH2-up CCND2-up|NCAM1-up CCND2-up|CD274-down HMOX1-down|CD274-down PDGFRA-down|CDH2-up MCL1-down|CDH2-up MMP16-up|CDH2-up PDGFRA-down|CDH2-up PLAU-up|CDH2-up SERPINB5-up|CDH2-up SOX4-up|CDH2-up THBS1-down|CDH2-up TNC-up|CDH2-up TP63-up|CDH3-up PLAU-up|CDH3-up TNC-up|CDH3-up TP63-up|CLDN18-down SERPINB5-up|CLDN1-up PLAU-up|CLDN1-up THBS1-down|CLDN5-down HMOX1-down|CLDN5-down THBS1-down|SELL-down HMOX1-down|VCAM1-up HMOX1-down|ITGB8-up MCL1-down|ITGB8-up THBS1-down|ITGB8-up TNC-up|NCAM1-up MCL1-down|SELL-down MCL1-down|VCAM1-up MCL1-down|NCAM1-up PDGFRA-down|NCAM1-up SOX4-up|NCAM1-up THBS1-down|NCAM1-up TNC-up|NFASC-up TNC-up|VCAM1-up PDGFRA-down|VCAM1-up PLAU-up|SELL-down SERPINB5-up|VCAM1-up THBS1-down|VCAM1-up TNC-up	CD274-down_29126 CCND1-up_595|CDH2-up_1000 CCND1-up_595|CDH3-up_1001 CCND1-up_595|NCAM1-up_4684 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CDH2-up_1000 CCND2-up_894|NCAM1-up_4684 CCND2-up_894|CD274-down_29126 HMOX1-down_3162|CD274-down_29126 PDGFRA-down_5156|CDH2-up_1000 MCL1-down_4170|CDH2-up_1000 MMP16-up_4325|CDH2-up_1000 PDGFRA-down_5156|CDH2-up_1000 PLAU-up_5328|CDH2-up_1000 SERPINB5-up_5268|CDH2-up_1000 SOX4-up_6659|CDH2-up_1000 THBS1-down_7057|CDH2-up_1000 TNC-up_3371|CDH2-up_1000 TP63-up_8626|CDH3-up_1001 PLAU-up_5328|CDH3-up_1001 TNC-up_3371|CDH3-up_1001 TP63-up_8626|CLDN18-down_51208 SERPINB5-up_5268|CLDN1-up_9076 PLAU-up_5328|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 HMOX1-down_3162|CLDN5-down_7122 THBS1-down_7057|SELL-down_6402 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|ITGB8-up_3696 MCL1-down_4170|ITGB8-up_3696 THBS1-down_7057|ITGB8-up_3696 TNC-up_3371|NCAM1-up_4684 MCL1-down_4170|SELL-down_6402 MCL1-down_4170|VCAM1-up_7412 MCL1-down_4170|NCAM1-up_4684 PDGFRA-down_5156|NCAM1-up_4684 SOX4-up_6659|NCAM1-up_4684 THBS1-down_7057|NCAM1-up_4684 TNC-up_3371|NFASC-up_23114 TNC-up_3371|VCAM1-up_7412 PDGFRA-down_5156|VCAM1-up_7412 PLAU-up_5328|SELL-down_6402 SERPINB5-up_5268|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 TNC-up_3371
hsa04514	hsa05219	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CD274-down CCND1-up|CDH2-up CCND1-up|CDH3-up CCND1-up|NCAM1-up CCND1-up|VCAM1-up CCND1-up|CDH2-up HBEGF-down|CDH2-up MMP1-up|CDH2-up MMP2-up|CDH2-up THBS1-down|CLDN1-up MMP1-up|CLDN1-up MMP2-up|CLDN1-up THBS1-down|CLDN5-down MMP1-up|CLDN5-down MMP2-up|CLDN5-down THBS1-down|SELL-down HBEGF-down|VCAM1-up HBEGF-down|ITGB8-up THBS1-down|NCAM1-up MMP1-up|VCAM1-up MMP1-up|NCAM1-up MMP2-up|SELL-down MMP2-up|VCAM1-up MMP2-up|NCAM1-up THBS1-down|VCAM1-up THBS1-down	CD274-down_29126 CCND1-up_595|CDH2-up_1000 CCND1-up_595|CDH3-up_1001 CCND1-up_595|NCAM1-up_4684 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CDH2-up_1000 HBEGF-down_1839|CDH2-up_1000 MMP1-up_4312|CDH2-up_1000 MMP2-up_4313|CDH2-up_1000 THBS1-down_7057|CLDN1-up_9076 MMP1-up_4312|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 MMP1-up_4312|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 THBS1-down_7057|SELL-down_6402 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|ITGB8-up_3696 THBS1-down_7057|NCAM1-up_4684 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|NCAM1-up_4684 MMP2-up_4313|SELL-down_6402 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|NCAM1-up_4684 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04514	hsa05323	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CD274-down CXCL12-up|CDH2-up CXCL12-up|CDH2-up FLT1-down|CDH2-up JUN-down|CDH2-up MMP1-up|CDH2-up TGFB3-up|CLDN1-up MMP1-up|CLDN5-down CXCL12-up|CLDN5-down FLT1-down|CLDN5-down JUN-down|CLDN5-down MMP1-up|VCAM1-up CTSK-up|NCAM1-up CXCL12-up|SELL-down CXCL12-up|VCAM1-up CXCL12-up|VTCN1-up CXCL12-up|NCAM1-up FLT1-down|SELL-down FLT1-down|VCAM1-up FLT1-down|ITGB8-up TGFB3-up|NCAM1-up JUN-down|SELL-down JUN-down|VCAM1-up JUN-down|NCAM1-up MMP1-up|VCAM1-up MMP1-up|NCAM1-up TGFB3-up|VCAM1-up TGFB3-up	CD274-down_29126 CXCL12-up_6387|CDH2-up_1000 CXCL12-up_6387|CDH2-up_1000 FLT1-down_2321|CDH2-up_1000 JUN-down_3725|CDH2-up_1000 MMP1-up_4312|CDH2-up_1000 TGFB3-up_7043|CLDN1-up_9076 MMP1-up_4312|CLDN5-down_7122 CXCL12-up_6387|CLDN5-down_7122 FLT1-down_2321|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MMP1-up_4312|VCAM1-up_7412 CTSK-up_1513|NCAM1-up_4684 CXCL12-up_6387|SELL-down_6402 CXCL12-up_6387|VCAM1-up_7412 CXCL12-up_6387|VTCN1-up_79679 CXCL12-up_6387|NCAM1-up_4684 FLT1-down_2321|SELL-down_6402 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|ITGB8-up_3696 TGFB3-up_7043|NCAM1-up_4684 JUN-down_3725|SELL-down_6402 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|NCAM1-up_4684 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|NCAM1-up_4684 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04514	hsa05410	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.002	CD274-down IGF1-up|CDH2-up IGF1-up|CDH2-up ITGB4-up|CDH2-up TGFB3-up|CDH2-up TTN-down|CDH3-up ITGB8-up|CLDN1-up ITGB4-up|CLDN5-down IGF1-up|NCAM1-up IGF1-up|SELL-down IGF1-up|VCAM1-up IGF1-up|NCAM1-up ITGB4-up|VCAM1-up ITGB4-up|NCAM1-up TGFB3-up|VCAM1-up TGFB3-up	CD274-down_29126 IGF1-up_3479|CDH2-up_1000 IGF1-up_3479|CDH2-up_1000 ITGB4-up_3691|CDH2-up_1000 TGFB3-up_7043|CDH2-up_1000 TTN-down_7273|CDH3-up_1001 ITGB8-up_3696|CLDN1-up_9076 ITGB4-up_3691|CLDN5-down_7122 IGF1-up_3479|NCAM1-up_4684 IGF1-up_3479|SELL-down_6402 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|NCAM1-up_4684 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|NCAM1-up_4684 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04514	hsa05412	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.035	CDH2-up CLDN5-down|CDH3-up ITGB8-up|CLDN1-up ITGB4-up|CLDN1-up TCF7L2-up|CLDN5-down TCF7L2-up|NCAM1-up ITGB4-up|VCAM1-up ITGB4-up	CDH2-up_1000 CLDN5-down_7122|CDH3-up_1001 ITGB8-up_3696|CLDN1-up_9076 ITGB4-up_3691|CLDN1-up_9076 TCF7L2-up_6934|CLDN5-down_7122 TCF7L2-up_6934|NCAM1-up_4684 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691
hsa04514	hsa05414	Cell adhesion molecules (CAMs) - Homo sapiens (human)	CD274,CLDN18,CLDN5,SELL,CDH2,CDH3,CLDN1,HLA-DOA,ITGB8,NCAM1,NFASC,VCAM1,VTCN1	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.01	CD274-down IGF1-up|CDH2-up IGF1-up|CDH2-up ITGB4-up|CDH2-up TGFB3-up|CDH2-up TTN-down|CDH3-up ITGB8-up|CLDN1-up ITGB4-up|CLDN5-down IGF1-up|NCAM1-up IGF1-up|SELL-down IGF1-up|VCAM1-up IGF1-up|NCAM1-up ITGB4-up|VCAM1-up ITGB4-up|NCAM1-up TGFB3-up|VCAM1-up TGFB3-up	CD274-down_29126 IGF1-up_3479|CDH2-up_1000 IGF1-up_3479|CDH2-up_1000 ITGB4-up_3691|CDH2-up_1000 TGFB3-up_7043|CDH2-up_1000 TTN-down_7273|CDH3-up_1001 ITGB8-up_3696|CLDN1-up_9076 ITGB4-up_3691|CLDN5-down_7122 IGF1-up_3479|NCAM1-up_4684 IGF1-up_3479|SELL-down_6402 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|NCAM1-up_4684 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|NCAM1-up_4684 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04550	hsa04610	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	0.018	IGF1-up CFH-up|IGF1-up F3-down|SOX2-up F3-down|ID1-down PLAU-up|ID1-down SERPINE1-down|IGF1-up SERPINE1-down|JAK1-down PLAU-up|JAK1-down SERPINE1-down	IGF1-up_3479 CFH-up_3075|IGF1-up_3479 F3-down_2152|SOX2-up_6657 F3-down_2152|ID1-down_3397 PLAU-up_5328|ID1-down_3397 SERPINE1-down_5054|IGF1-up_3479 SERPINE1-down_5054|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 SERPINE1-down_5054
hsa04550	hsa04668	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	IGF1-up CXCL2-down|FZD5-down JUN-down|FZD5-down MAP3K8-down|ID1-down JUN-down|IGF1-up IL18R1-down|IGF1-up JUN-down|IGF1-up MAP3K8-down|IGF1-up SOCS3-down|IGF1-up VCAM1-up|JAK1-down JUN-down|JAK1-down SOCS3-down|JAK1-down VCAM1-up|LIFR-down JUN-down|SOX2-up JUN-down|LIFR-down SOCS3-down|LIFR-down VCAM1-up|SOX2-up SOCS3-down	IGF1-up_3479 CXCL2-down_2920|FZD5-down_7855 JUN-down_3725|FZD5-down_7855 MAP3K8-down_1326|ID1-down_3397 JUN-down_3725|IGF1-up_3479 IL18R1-down_8809|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MAP3K8-down_1326|IGF1-up_3479 SOCS3-down_9021|IGF1-up_3479 VCAM1-up_7412|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 SOCS3-down_9021|JAK1-down_3716 VCAM1-up_7412|LIFR-down_3977 JUN-down_3725|SOX2-up_6657 JUN-down_3725|LIFR-down_3977 SOCS3-down_9021|LIFR-down_3977 VCAM1-up_7412|SOX2-up_6657 SOCS3-down_9021
hsa04550	hsa04670	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	IGF1-up CLDN5-down|ID1-down CXCL12-up|IGF1-up CXCL12-up|JAK1-down CXCL12-up|LIFR-down CXCL12-up|SOX2-up CXCL12-up|ID1-down MMP2-up|ID1-down THY1-up|IGF1-up MMP2-up|IGF1-up THY1-up|IGF1-up VCAM1-up|JAK1-down MMP2-up|JAK1-down VCAM1-up|LIFR-down VCAM1-up|SOX2-up MMP2-up|SOX2-up THY1-up	IGF1-up_3479 CLDN5-down_7122|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|JAK1-down_3716 CXCL12-up_6387|LIFR-down_3977 CXCL12-up_6387|SOX2-up_6657 CXCL12-up_6387|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THY1-up_7070|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THY1-up_7070|IGF1-up_3479 VCAM1-up_7412|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 VCAM1-up_7412|LIFR-down_3977 VCAM1-up_7412|SOX2-up_6657 MMP2-up_4313|SOX2-up_6657 THY1-up_7070
hsa04550	hsa04915	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	FZD5-down GABBR2-up|FZD5-down JUN-down|JAK1-down GABBR2-up|IGF1-up HBEGF-down|LIFR-down HBEGF-down|IGF1-up HSPA1A-down|JAK1-down HSPA1A-down|JAK1-down HSPA1B-down|ID1-down JUN-down|ID1-down MMP2-up|IGF1-up JUN-down|IGF1-up MMP2-up|JAK1-down JUN-down|JAK1-down MMP2-up|LIFR-down JUN-down|SOX2-up JUN-down|SOX2-up MMP2-up	FZD5-down_7855 GABBR2-up_9568|FZD5-down_7855 JUN-down_3725|JAK1-down_3716 GABBR2-up_9568|IGF1-up_3479 HBEGF-down_1839|LIFR-down_3977 HBEGF-down_1839|IGF1-up_3479 HSPA1A-down_3303|JAK1-down_3716 HSPA1A-down_3303|JAK1-down_3716 HSPA1B-down_3304|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP2-up_4313|LIFR-down_3977 JUN-down_3725|SOX2-up_6657 JUN-down_3725|SOX2-up_6657 MMP2-up_4313
hsa04550	hsa04921	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Oxytocin signaling pathway - Homo sapiens (human)	JUN,NPR1,CCND1,GUCY1A3,KCNJ5,PRKAA2	0.045	FZD5-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|JAK1-down CCND1-up|LIFR-down CCND1-up|SOX2-up CCND1-up|FZD5-down JUN-down|ID1-down JUN-down|IGF1-up JUN-down|IGF1-up PRKAA2-up|JAK1-down JUN-down|LIFR-down JUN-down|SOX2-up JUN-down	FZD5-down_7855 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LIFR-down_3977 CCND1-up_595|SOX2-up_6657 CCND1-up_595|FZD5-down_7855 JUN-down_3725|ID1-down_3397 JUN-down_3725|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PRKAA2-up_5563|JAK1-down_3716 JUN-down_3725|LIFR-down_3977 JUN-down_3725|SOX2-up_6657 JUN-down_3725
hsa04550	hsa04933	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0	FZD5-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|JAK1-down CCND1-up|LIFR-down CCND1-up|SOX2-up CCND1-up|IGF1-up COL1A1-up|SOX2-up COL1A1-up|IGF1-up COL1A2-up|JAK1-down COL1A2-up|SOX2-up COL1A2-up|IGF1-up COL3A1-up|IGF1-up F3-down|SOX2-up F3-down|IGF1-up FIGF-down|FZD5-down JUN-down|ID1-down JUN-down|ID1-down MMP2-up|ID1-down SERPINE1-down|ID1-down TGFB3-up|IGF1-up JUN-down|IGF1-up MMP2-up|IGF1-up SERPINE1-down|IGF1-up TGFB3-up|IGF1-up VCAM1-up|JAK1-down JUN-down|JAK1-down MMP2-up|JAK1-down SERPINE1-down|JAK1-down VCAM1-up|LIFR-down JUN-down|SOX2-up JUN-down|LIFR-down VCAM1-up|SOX2-up MMP2-up	FZD5-down_7855 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LIFR-down_3977 CCND1-up_595|SOX2-up_6657 CCND1-up_595|IGF1-up_3479 COL1A1-up_1277|SOX2-up_6657 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|JAK1-down_3716 COL1A2-up_1278|SOX2-up_6657 COL1A2-up_1278|IGF1-up_3479 COL3A1-up_1281|IGF1-up_3479 F3-down_2152|SOX2-up_6657 F3-down_2152|IGF1-up_3479 FIGF-down_2277|FZD5-down_7855 JUN-down_3725|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP2-up_4313|ID1-down_3397 SERPINE1-down_5054|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 SERPINE1-down_5054|IGF1-up_3479 TGFB3-up_7043|IGF1-up_3479 VCAM1-up_7412|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 SERPINE1-down_5054|JAK1-down_3716 VCAM1-up_7412|LIFR-down_3977 JUN-down_3725|SOX2-up_6657 JUN-down_3725|LIFR-down_3977 VCAM1-up_7412|SOX2-up_6657 MMP2-up_4313
hsa04550	hsa05146	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.03	IGF1-up COL1A1-up|SOX2-up COL1A1-up|IGF1-up COL1A2-up|JAK1-down COL1A2-up|SOX2-up COL1A2-up|IGF1-up COL3A1-up|ID1-down TGFB3-up|IGF1-up TGFB3-up	IGF1-up_3479 COL1A1-up_1277|SOX2-up_6657 COL1A1-up_1277|IGF1-up_3479 COL1A2-up_1278|JAK1-down_3716 COL1A2-up_1278|SOX2-up_6657 COL1A2-up_1278|IGF1-up_3479 COL3A1-up_1281|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 TGFB3-up_7043
hsa04550	hsa05202	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	FZD5-down CCND2-up|JAK1-down CCND2-up|SOX2-up CCND2-up|FZD5-down FLT1-down|ID1-down FLT1-down|JAK1-down FLT1-down|SOX2-up FLT1-down|FZD5-down PROM1-up|ID1-down IGF1-up|ID1-down PLAU-up|IGF1-up JAK1-down|IGF1-up LIFR-down|JAK1-down PLAU-up|JAK1-down ZBTB16-down|SOX2-up PROM1-up|SOX2-up SIX1-up|SOX2-up SIX4-up|SOX2-up ZBTB16-down	FZD5-down_7855 CCND2-up_894|JAK1-down_3716 CCND2-up_894|SOX2-up_6657 CCND2-up_894|FZD5-down_7855 FLT1-down_2321|ID1-down_3397 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|SOX2-up_6657 FLT1-down_2321|FZD5-down_7855 PROM1-up_8842|ID1-down_3397 IGF1-up_3479|ID1-down_3397 PLAU-up_5328|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LIFR-down_3977|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|SOX2-up_6657 PROM1-up_8842|SOX2-up_6657 SIX1-up_6495|SOX2-up_6657 SIX4-up_51804|SOX2-up_6657 ZBTB16-down_7704
hsa04550	hsa05205	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.033	ID1-down CCND1-up|JAK1-down CCND1-up|LIFR-down CCND1-up|SOX2-up CCND1-up|LIFR-down HBEGF-down|ID1-down IGF1-up|ID1-down MMP2-up|ID1-down PLAU-up|ID1-down THBS1-down|IGF1-up JAK1-down|IGF1-up LIFR-down|JAK1-down MMP2-up|JAK1-down PLAU-up|SOX2-up MMP2-up|SOX2-up THBS1-down	ID1-down_3397 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LIFR-down_3977 CCND1-up_595|SOX2-up_6657 CCND1-up_595|LIFR-down_3977 HBEGF-down_1839|ID1-down_3397 IGF1-up_3479|ID1-down_3397 MMP2-up_4313|ID1-down_3397 PLAU-up_5328|ID1-down_3397 THBS1-down_7057|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 LIFR-down_3977|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|SOX2-up_6657 MMP2-up_4313|SOX2-up_6657 THBS1-down_7057
hsa04550	hsa05206	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	FZD5-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|JAK1-down CCND1-up|LIFR-down CCND1-up|SOX2-up CCND1-up|FZD5-down CCND2-up|IGF1-up CCND2-up|JAK1-down CCND2-up|SOX2-up CCND2-up|IGF1-up CYP24A1-up|FZD5-down PDGFRA-down|IGF1-up HMOX1-down|JAK1-down HMOX1-down|SOX2-up HMOX1-down|ID1-down PDGFRA-down|ID1-down PLAU-up|ID1-down THBS1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|IGF1-up TNC-up|JAK1-down IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|SOX2-up MCL1-down|SOX2-up PDGFRA-down|SOX2-up SOX4-up|SOX2-up THBS1-down|SOX2-up TNC-up|SOX2-up TP63-up	FZD5-down_7855 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LIFR-down_3977 CCND1-up_595|SOX2-up_6657 CCND1-up_595|FZD5-down_7855 CCND2-up_894|IGF1-up_3479 CCND2-up_894|JAK1-down_3716 CCND2-up_894|SOX2-up_6657 CCND2-up_894|IGF1-up_3479 CYP24A1-up_1591|FZD5-down_7855 PDGFRA-down_5156|IGF1-up_3479 HMOX1-down_3162|JAK1-down_3716 HMOX1-down_3162|SOX2-up_6657 HMOX1-down_3162|ID1-down_3397 PDGFRA-down_5156|ID1-down_3397 PLAU-up_5328|ID1-down_3397 THBS1-down_7057|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 TNC-up_3371|JAK1-down_3716 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|SOX2-up_6657 MCL1-down_4170|SOX2-up_6657 PDGFRA-down_5156|SOX2-up_6657 SOX4-up_6659|SOX2-up_6657 THBS1-down_7057|SOX2-up_6657 TNC-up_3371|SOX2-up_6657 TP63-up_8626
hsa04550	hsa05219	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	FZD5-down CCND1-up|ID1-down CCND1-up|IGF1-up CCND1-up|JAK1-down CCND1-up|LIFR-down CCND1-up|SOX2-up CCND1-up|IGF1-up HBEGF-down|LIFR-down HBEGF-down|ID1-down MMP1-up|ID1-down MMP2-up|ID1-down THBS1-down|IGF1-up MMP1-up|IGF1-up MMP2-up|IGF1-up THBS1-down|JAK1-down MMP1-up|JAK1-down MMP2-up|SOX2-up MMP2-up|SOX2-up THBS1-down	FZD5-down_7855 CCND1-up_595|ID1-down_3397 CCND1-up_595|IGF1-up_3479 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LIFR-down_3977 CCND1-up_595|SOX2-up_6657 CCND1-up_595|IGF1-up_3479 HBEGF-down_1839|LIFR-down_3977 HBEGF-down_1839|ID1-down_3397 MMP1-up_4312|ID1-down_3397 MMP2-up_4313|ID1-down_3397 THBS1-down_7057|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THBS1-down_7057|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|SOX2-up_6657 MMP2-up_4313|SOX2-up_6657 THBS1-down_7057
hsa04550	hsa05323	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	IGF1-up CTSK-up|ID1-down CXCL12-up|IGF1-up CXCL12-up|JAK1-down CXCL12-up|LIFR-down CXCL12-up|SOX2-up CXCL12-up|FZD5-down FLT1-down|ID1-down FLT1-down|IGF1-up FLT1-down|JAK1-down FLT1-down|SOX2-up FLT1-down|FZD5-down JUN-down|ID1-down JUN-down|ID1-down MMP1-up|ID1-down TGFB3-up|IGF1-up JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|JAK1-down JUN-down|JAK1-down MMP1-up|LIFR-down JUN-down|SOX2-up JUN-down	IGF1-up_3479 CTSK-up_1513|ID1-down_3397 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|JAK1-down_3716 CXCL12-up_6387|LIFR-down_3977 CXCL12-up_6387|SOX2-up_6657 CXCL12-up_6387|FZD5-down_7855 FLT1-down_2321|ID1-down_3397 FLT1-down_2321|IGF1-up_3479 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|SOX2-up_6657 FLT1-down_2321|FZD5-down_7855 JUN-down_3725|ID1-down_3397 JUN-down_3725|ID1-down_3397 MMP1-up_4312|ID1-down_3397 TGFB3-up_7043|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP1-up_4312|LIFR-down_3977 JUN-down_3725|SOX2-up_6657 JUN-down_3725
hsa04550	hsa05412	Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)	FZD5,ID1,JAK1,LIFR,IGF1,SOX2	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.031	FZD5-down CDH2-up|IGF1-up CDH2-up|JAK1-down CDH2-up|SOX2-up CDH2-up|FZD5-down ITGB8-up|FZD5-down TCF7L2-up|IGF1-up TCF7L2-up	FZD5-down_7855 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|SOX2-up_6657 CDH2-up_1000|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 TCF7L2-up_6934|IGF1-up_3479 TCF7L2-up_6934
hsa04610	hsa04630	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	0.003	CFH-up CCND1-up|PLAU-up CCND1-up|SERPINE1-down CCND1-up|PLAU-up CCND2-up|SERPINE1-down CCND2-up|F3-down SOCS3-down|PLAU-up JAK1-down|SERPINE1-down JAK1-down|SERPINE1-down MCL1-down|TFPI-down MCL1-down|PLAU-up SOCS3-down|SERPINE1-down SOCS3-down	CFH-up_3075 CCND1-up_595|PLAU-up_5328 CCND1-up_595|SERPINE1-down_5054 CCND1-up_595|PLAU-up_5328 CCND2-up_894|SERPINE1-down_5054 CCND2-up_894|F3-down_2152 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|SERPINE1-down_5054 MCL1-down_4170|TFPI-down_7035 MCL1-down_4170|PLAU-up_5328 SOCS3-down_9021|SERPINE1-down_5054 SOCS3-down_9021
hsa04610	hsa04668	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0	CFH-up JUN-down|PLAU-up CXCL2-down|F3-down CXCL3-down|PLAU-up CXCL3-down|F3-down JUN-down|F3-down SOCS3-down|F3-down VCAM1-up|PLAU-up JUN-down|SERPINE1-down JUN-down|TFPI-down JUN-down|PLAU-up MAP3K8-down|SERPINE1-down MAP3K8-down|PLAU-up SOCS3-down|PLAU-up VCAM1-up|SERPINE1-down SOCS3-down|SERPINE1-down VCAM1-up|TFPI-down VCAM1-up	CFH-up_3075 JUN-down_3725|PLAU-up_5328 CXCL2-down_2920|F3-down_2152 CXCL3-down_2921|PLAU-up_5328 CXCL3-down_2921|F3-down_2152 JUN-down_3725|F3-down_2152 SOCS3-down_9021|F3-down_2152 VCAM1-up_7412|PLAU-up_5328 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|TFPI-down_7035 JUN-down_3725|PLAU-up_5328 MAP3K8-down_1326|SERPINE1-down_5054 MAP3K8-down_1326|PLAU-up_5328 SOCS3-down_9021|PLAU-up_5328 VCAM1-up_7412|SERPINE1-down_5054 SOCS3-down_9021|SERPINE1-down_5054 VCAM1-up_7412|TFPI-down_7035 VCAM1-up_7412
hsa04610	hsa04670	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0	CFH-up MMP2-up|PLAU-up CLDN1-up|SERPINE1-down CLDN5-down|F3-down CXCL12-up|PLAU-up CXCL12-up|SERPINE1-down CXCL12-up|TFPI-down CXCL12-up|F3-down MMP2-up|F3-down VCAM1-up|PLAU-up MMP2-up|SERPIND1-up MMP2-up|SERPINE1-down MMP2-up|TFPI-down MMP2-up|PLAU-up VCAM1-up|SERPINE1-down THY1-up|SERPINE1-down VCAM1-up|TFPI-down VCAM1-up	CFH-up_3075 MMP2-up_4313|PLAU-up_5328 CLDN1-up_9076|SERPINE1-down_5054 CLDN5-down_7122|F3-down_2152 CXCL12-up_6387|PLAU-up_5328 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|TFPI-down_7035 CXCL12-up_6387|F3-down_2152 MMP2-up_4313|F3-down_2152 VCAM1-up_7412|PLAU-up_5328 MMP2-up_4313|SERPIND1-up_3053 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|TFPI-down_7035 MMP2-up_4313|PLAU-up_5328 VCAM1-up_7412|SERPINE1-down_5054 THY1-up_7070|SERPINE1-down_5054 VCAM1-up_7412|TFPI-down_7035 VCAM1-up_7412
hsa04610	hsa04915	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.001	CFH-up JUN-down|CFH-up MMP2-up|F3-down HBEGF-down|F3-down HSPA1A-down|F3-down JUN-down|F3-down MMP2-up|PLAU-up HBEGF-down|SERPINE1-down HBEGF-down|PLAU-up JUN-down|SERPINE1-down JUN-down|TFPI-down JUN-down|PLAU-up MMP2-up|SERPIND1-up MMP2-up|SERPINE1-down MMP2-up|TFPI-down MMP2-up	CFH-up_3075 JUN-down_3725|CFH-up_3075 MMP2-up_4313|F3-down_2152 HBEGF-down_1839|F3-down_2152 HSPA1A-down_3303|F3-down_2152 JUN-down_3725|F3-down_2152 MMP2-up_4313|PLAU-up_5328 HBEGF-down_1839|SERPINE1-down_5054 HBEGF-down_1839|PLAU-up_5328 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|TFPI-down_7035 JUN-down_3725|PLAU-up_5328 MMP2-up_4313|SERPIND1-up_3053 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|TFPI-down_7035 MMP2-up_4313
hsa04610	hsa04974	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CFH-up COL10A1-up|CFH-up COL17A1-up|TFPI-down COL14A1-up|F3-down COL15A1-up|PLAU-up COL15A1-up|F3-down COL18A1-up|PLAU-up COL18A1-up|SERPINE1-down COL18A1-up|TFPI-down COL18A1-up|PLAU-up COL1A1-up|SERPINE1-down COL1A1-up|PLAU-up COL1A2-up|SERPINE1-down COL1A2-up|PLAU-up COL3A1-up|SERPINE1-down COL3A1-up|PLAU-up COL5A1-up|SERPINE1-down COL5A1-up|PLAU-up COL5A2-up|SERPINE1-down COL5A2-up|PLAU-up COL6A3-up|SERPINE1-down COL7A1-up|PLAU-up MME-down|SERPINE1-down MME-down|TFPI-down MME-down|PLAU-up PRSS1-up|SERPINE1-down PRSS1-up	CFH-up_3075 COL10A1-up_1300|CFH-up_3075 COL17A1-up_1308|TFPI-down_7035 COL14A1-up_7373|F3-down_2152 COL15A1-up_1306|PLAU-up_5328 COL15A1-up_1306|F3-down_2152 COL18A1-up_80781|PLAU-up_5328 COL18A1-up_80781|SERPINE1-down_5054 COL18A1-up_80781|TFPI-down_7035 COL18A1-up_80781|PLAU-up_5328 COL1A1-up_1277|SERPINE1-down_5054 COL1A1-up_1277|PLAU-up_5328 COL1A2-up_1278|SERPINE1-down_5054 COL1A2-up_1278|PLAU-up_5328 COL3A1-up_1281|SERPINE1-down_5054 COL3A1-up_1281|PLAU-up_5328 COL5A1-up_1289|SERPINE1-down_5054 COL5A1-up_1289|PLAU-up_5328 COL5A2-up_1290|SERPINE1-down_5054 COL5A2-up_1290|PLAU-up_5328 COL6A3-up_1293|SERPINE1-down_5054 COL7A1-up_1294|PLAU-up_5328 MME-down_4311|SERPINE1-down_5054 MME-down_4311|TFPI-down_7035 MME-down_4311|PLAU-up_5328 PRSS1-up_5644|SERPINE1-down_5054 PRSS1-up_5644
hsa04610	hsa04978	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.009	CFH-up TF-up|F3-down HMOX1-down|F3-down TF-up|PLAU-up HMOX1-down|SERPINE1-down HMOX1-down|TFPI-down HMOX1-down|PLAU-up TF-up|SERPIND1-up TF-up|SERPINE1-down TF-up|TFPI-down TF-up	CFH-up_3075 TF-up_7018|F3-down_2152 HMOX1-down_3162|F3-down_2152 TF-up_7018|PLAU-up_5328 HMOX1-down_3162|SERPINE1-down_5054 HMOX1-down_3162|TFPI-down_7035 HMOX1-down_3162|PLAU-up_5328 TF-up_7018|SERPIND1-up_3053 TF-up_7018|SERPINE1-down_5054 TF-up_7018|TFPI-down_7035 TF-up_7018
hsa04610	hsa05145	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0.009	CFH-up LDLR-down|F3-down HSPA1A-down|PLAU-up JAK1-down|SERPINE1-down JAK1-down|PLAU-up LAMA3-down|SERPINE1-down LAMA3-down|SERPINE1-down LDLR-down|TFPI-down LDLR-down|PLAU-up TGFB3-up|SERPINE1-down TGFB3-up	CFH-up_3075 LDLR-down_3949|F3-down_2152 HSPA1A-down_3303|PLAU-up_5328 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|PLAU-up_5328 LAMA3-down_3909|SERPINE1-down_5054 LAMA3-down_3909|SERPINE1-down_5054 LDLR-down_3949|TFPI-down_7035 LDLR-down_3949|PLAU-up_5328 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04610	hsa05146	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	PLAU-up COL1A1-up|SERPINE1-down COL1A1-up|PLAU-up COL1A2-up|SERPINE1-down COL1A2-up|PLAU-up COL3A1-up|SERPINE1-down COL3A1-up|F3-down IL1R2-down|PLAU-up LAMA3-down|SERPINE1-down LAMA3-down|PLAU-up SERPINB3-up|PLAU-up TGFB3-up|SERPIND1-up SERPINB3-up|SERPINE1-down SERPINB3-up|SERPINE1-down TGFB3-up	PLAU-up_5328 COL1A1-up_1277|SERPINE1-down_5054 COL1A1-up_1277|PLAU-up_5328 COL1A2-up_1278|SERPINE1-down_5054 COL1A2-up_1278|PLAU-up_5328 COL3A1-up_1281|SERPINE1-down_5054 COL3A1-up_1281|F3-down_2152 IL1R2-down_7850|PLAU-up_5328 LAMA3-down_3909|SERPINE1-down_5054 LAMA3-down_3909|PLAU-up_5328 SERPINB3-up_6317|PLAU-up_5328 TGFB3-up_7043|SERPIND1-up_3053 SERPINB3-up_6317|SERPINE1-down_5054 SERPINB3-up_6317|SERPINE1-down_5054 TGFB3-up_7043
hsa04610	hsa05152	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.042	C7-up CD74-up|PLAU-up CLEC4E-down|PLAU-up JAK1-down|SERPINE1-down JAK1-down|PLAU-up TGFB3-up|SERPINE1-down TGFB3-up	C7-up_730 CD74-up_972|PLAU-up_5328 CLEC4E-down_26253|PLAU-up_5328 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|PLAU-up_5328 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04610	hsa05160	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0.002	CFH-up LDLR-down|PLAU-up CLDN1-up|SERPINE1-down CLDN5-down|F3-down SOCS3-down|PLAU-up JAK1-down|SERPINE1-down JAK1-down|SERPINE1-down LDLR-down|TFPI-down LDLR-down|PLAU-up SOCS3-down|SERPINE1-down SOCS3-down	CFH-up_3075 LDLR-down_3949|PLAU-up_5328 CLDN1-up_9076|SERPINE1-down_5054 CLDN5-down_7122|F3-down_2152 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|SERPINE1-down_5054 LDLR-down_3949|TFPI-down_7035 LDLR-down_3949|PLAU-up_5328 SOCS3-down_9021|SERPINE1-down_5054 SOCS3-down_9021
hsa04610	hsa05164	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0	CFH-up JUN-down|F3-down HSPA1A-down|F3-down JUN-down|F3-down SOCS3-down|PLAU-up JAK1-down|SERPINE1-down JAK1-down|PLAU-up JUN-down|SERPINE1-down JUN-down|TFPI-down JUN-down|PLAU-up PRSS1-up|PLAU-up SOCS3-down|PLAU-up TMPRSS4-up|SERPINE1-down PRSS1-up|SERPINE1-down SOCS3-down|SERPINE1-down TMPRSS4-up	CFH-up_3075 JUN-down_3725|F3-down_2152 HSPA1A-down_3303|F3-down_2152 JUN-down_3725|F3-down_2152 SOCS3-down_9021|PLAU-up_5328 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|TFPI-down_7035 JUN-down_3725|PLAU-up_5328 PRSS1-up_5644|PLAU-up_5328 SOCS3-down_9021|PLAU-up_5328 TMPRSS4-up_56649|SERPINE1-down_5054 PRSS1-up_5644|SERPINE1-down_5054 SOCS3-down_9021|SERPINE1-down_5054 TMPRSS4-up_56649
hsa04610	hsa05166	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.009	CFH-up CCND1-up|PLAU-up CCND1-up|SERPINE1-down CCND1-up|PLAU-up CCND2-up|SERPINE1-down CCND2-up|CFH-up JUN-down|CFH-up PDGFRA-down|F3-down IL1R2-down|F3-down JUN-down|F3-down PDGFRA-down|F3-down VCAM1-up|PLAU-up JAK1-down|SERPINE1-down JAK1-down|PLAU-up JUN-down|SERPINE1-down JUN-down|TFPI-down JUN-down|SERPINE1-down MYB-up|PLAU-up PDGFRA-down|PLAU-up TGFB3-up|PLAU-up VCAM1-up|SERPINE1-down TGFB3-up|SERPINE1-down VCAM1-up|TFPI-down VCAM1-up	CFH-up_3075 CCND1-up_595|PLAU-up_5328 CCND1-up_595|SERPINE1-down_5054 CCND1-up_595|PLAU-up_5328 CCND2-up_894|SERPINE1-down_5054 CCND2-up_894|CFH-up_3075 JUN-down_3725|CFH-up_3075 PDGFRA-down_5156|F3-down_2152 IL1R2-down_7850|F3-down_2152 JUN-down_3725|F3-down_2152 PDGFRA-down_5156|F3-down_2152 VCAM1-up_7412|PLAU-up_5328 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|TFPI-down_7035 JUN-down_3725|SERPINE1-down_5054 MYB-up_4602|PLAU-up_5328 PDGFRA-down_5156|PLAU-up_5328 TGFB3-up_7043|PLAU-up_5328 VCAM1-up_7412|SERPINE1-down_5054 TGFB3-up_7043|SERPINE1-down_5054 VCAM1-up_7412|TFPI-down_7035 VCAM1-up_7412
hsa04610	hsa05200	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	CFH-up CCND1-up|PLAU-up CCND1-up|SERPINE1-down CCND1-up|CFH-up EDNRB-down|CFH-up IGF1-up|CFH-up JUN-down|CFH-up MMP2-up|CFH-up PDGFRA-down|CFH-up ZBTB16-down|F3-down CXCL12-up|PLAU-up CXCL12-up|SERPINE1-down CXCL12-up|TFPI-down CXCL12-up|SERPINE1-down EDNRB-down|TFPI-down EDNRB-down|F3-down IGF1-up|F3-down JUN-down|F3-down MMP2-up|F3-down PDGFRA-down|PLAU-up FIGF-down|SERPINE1-down FIGF-down|SERPINE1-down IGF1-up|PLAU-up JAK1-down|SERPINE1-down JAK1-down|PLAU-up JUN-down|SERPINE1-down JUN-down|TFPI-down JUN-down|PLAU-up LAMA3-down|SERPINE1-down LAMA3-down|MASP1-up TCF7L2-up|PLAU-up MMP1-up|SERPINE1-down MMP1-up|TFPI-down MMP1-up|PLAU-up MMP2-up|SERPIND1-up MMP2-up|SERPINE1-down MMP2-up|TFPI-down MMP2-up|PLAU-up PDGFRA-down|PLAU-up TGFB3-up|SERPINE1-down TGFB3-up	CFH-up_3075 CCND1-up_595|PLAU-up_5328 CCND1-up_595|SERPINE1-down_5054 CCND1-up_595|CFH-up_3075 EDNRB-down_1910|CFH-up_3075 IGF1-up_3479|CFH-up_3075 JUN-down_3725|CFH-up_3075 MMP2-up_4313|CFH-up_3075 PDGFRA-down_5156|CFH-up_3075 ZBTB16-down_7704|F3-down_2152 CXCL12-up_6387|PLAU-up_5328 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|TFPI-down_7035 CXCL12-up_6387|SERPINE1-down_5054 EDNRB-down_1910|TFPI-down_7035 EDNRB-down_1910|F3-down_2152 IGF1-up_3479|F3-down_2152 JUN-down_3725|F3-down_2152 MMP2-up_4313|F3-down_2152 PDGFRA-down_5156|PLAU-up_5328 FIGF-down_2277|SERPINE1-down_5054 FIGF-down_2277|SERPINE1-down_5054 IGF1-up_3479|PLAU-up_5328 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|PLAU-up_5328 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|TFPI-down_7035 JUN-down_3725|PLAU-up_5328 LAMA3-down_3909|SERPINE1-down_5054 LAMA3-down_3909|MASP1-up_5648 TCF7L2-up_6934|PLAU-up_5328 MMP1-up_4312|SERPINE1-down_5054 MMP1-up_4312|TFPI-down_7035 MMP1-up_4312|PLAU-up_5328 MMP2-up_4313|SERPIND1-up_3053 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|TFPI-down_7035 MMP2-up_4313|PLAU-up_5328 PDGFRA-down_5156|PLAU-up_5328 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04610	hsa05202	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.003	SERPINE1-down CCND2-up|CFH-up FLT1-down|CFH-up IGF1-up|CFH-up PLAU-up|CFH-up ZBTB16-down|F3-down FLT1-down|F3-down IGF1-up|F3-down IL1R2-down|F3-down PLAU-up|SERPINE1-down FLT1-down|TFPI-down FLT1-down|SERPINE1-down IGF1-up|TFPI-down NFKBIZ-down|PLAU-up SERPINE1-down|PLAU-up TFPI-down|SERPINE1-down PROM1-up	SERPINE1-down_5054 CCND2-up_894|CFH-up_3075 FLT1-down_2321|CFH-up_3075 IGF1-up_3479|CFH-up_3075 PLAU-up_5328|CFH-up_3075 ZBTB16-down_7704|F3-down_2152 FLT1-down_2321|F3-down_2152 IGF1-up_3479|F3-down_2152 IL1R2-down_7850|F3-down_2152 PLAU-up_5328|SERPINE1-down_5054 FLT1-down_2321|TFPI-down_7035 FLT1-down_2321|SERPINE1-down_5054 IGF1-up_3479|TFPI-down_7035 NFKBIZ-down_64332|PLAU-up_5328 SERPINE1-down_5054|PLAU-up_5328 TFPI-down_7035|SERPINE1-down_5054 PROM1-up_8842
hsa04610	hsa05205	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	F3-down CAV2-down|SERPINE1-down CAV2-down|CFH-up CCND1-up|SERPINE1-down CCND1-up|CFH-up IGF1-up|CFH-up MMP2-up|CFH-up PLAU-up|CFH-up THBS1-down|F3-down FLNC-up|F3-down HBEGF-down|F3-down IGF1-up|F3-down MMP2-up|F3-down PLAU-up|F3-down THBS1-down|TFPI-down FLNC-up|SERPINE1-down HBEGF-down|SERPINE1-down IGF1-up|SERPIND1-up MMP2-up|SERPINE1-down MMP2-up|TFPI-down MMP2-up|PLAU-up SERPINE1-down|PLAU-up TFPI-down|SERPINE1-down THBS1-down|TFPI-down THBS1-down	F3-down_2152 CAV2-down_858|SERPINE1-down_5054 CAV2-down_858|CFH-up_3075 CCND1-up_595|SERPINE1-down_5054 CCND1-up_595|CFH-up_3075 IGF1-up_3479|CFH-up_3075 MMP2-up_4313|CFH-up_3075 PLAU-up_5328|CFH-up_3075 THBS1-down_7057|F3-down_2152 FLNC-up_2318|F3-down_2152 HBEGF-down_1839|F3-down_2152 IGF1-up_3479|F3-down_2152 MMP2-up_4313|F3-down_2152 PLAU-up_5328|F3-down_2152 THBS1-down_7057|TFPI-down_7035 FLNC-up_2318|SERPINE1-down_5054 HBEGF-down_1839|SERPINE1-down_5054 IGF1-up_3479|SERPIND1-up_3053 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|TFPI-down_7035 MMP2-up_4313|PLAU-up_5328 SERPINE1-down_5054|PLAU-up_5328 TFPI-down_7035|SERPINE1-down_5054 THBS1-down_7057|TFPI-down_7035 THBS1-down_7057
hsa04610	hsa05206	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CFH-up CCND1-up|SERPINE1-down CCND1-up|SERPINE1-down CCND2-up|CFH-up PDGFRA-down|CFH-up PLAU-up|CFH-up THBS1-down|CFH-up TP63-up|F3-down HMOX1-down|F3-down PDGFRA-down|F3-down PLAU-up|F3-down THBS1-down|F3-down TNC-up|SERPINE1-down HMOX1-down|TFPI-down HMOX1-down|SERPINE1-down IRS2-down|MASP1-up SERPINB5-up|SERPINE1-down MCL1-down|TFPI-down MCL1-down|SERPINE1-down MMP16-up|PLAU-up SERPINE1-down|PLAU-up TFPI-down|SERPIND1-up SERPINB5-up|SERPINE1-down SERPINB5-up|SERPINE1-down THBS1-down|SERPINE1-down TNC-up|SERPINE1-down TP63-up|TFPI-down THBS1-down|TFPI-down TNC-up|TFPI-down TP63-up	CFH-up_3075 CCND1-up_595|SERPINE1-down_5054 CCND1-up_595|SERPINE1-down_5054 CCND2-up_894|CFH-up_3075 PDGFRA-down_5156|CFH-up_3075 PLAU-up_5328|CFH-up_3075 THBS1-down_7057|CFH-up_3075 TP63-up_8626|F3-down_2152 HMOX1-down_3162|F3-down_2152 PDGFRA-down_5156|F3-down_2152 PLAU-up_5328|F3-down_2152 THBS1-down_7057|F3-down_2152 TNC-up_3371|SERPINE1-down_5054 HMOX1-down_3162|TFPI-down_7035 HMOX1-down_3162|SERPINE1-down_5054 IRS2-down_8660|MASP1-up_5648 SERPINB5-up_5268|SERPINE1-down_5054 MCL1-down_4170|TFPI-down_7035 MCL1-down_4170|SERPINE1-down_5054 MMP16-up_4325|PLAU-up_5328 SERPINE1-down_5054|PLAU-up_5328 TFPI-down_7035|SERPIND1-up_3053 SERPINB5-up_5268|SERPINE1-down_5054 SERPINB5-up_5268|SERPINE1-down_5054 THBS1-down_7057|SERPINE1-down_5054 TNC-up_3371|SERPINE1-down_5054 TP63-up_8626|TFPI-down_7035 THBS1-down_7057|TFPI-down_7035 TNC-up_3371|TFPI-down_7035 TP63-up_8626
hsa04610	hsa05219	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CFH-up CCND1-up|PLAU-up CCND1-up|SERPINE1-down CCND1-up|CFH-up MMP2-up|CFH-up THBS1-down|F3-down HBEGF-down|F3-down MMP2-up|F3-down THBS1-down|PLAU-up HBEGF-down|SERPINE1-down HBEGF-down|PLAU-up MMP1-up|SERPINE1-down MMP1-up|TFPI-down MMP1-up|PLAU-up MMP2-up|SERPIND1-up MMP2-up|SERPINE1-down MMP2-up|TFPI-down MMP2-up|PLAU-up THBS1-down|SERPINE1-down THBS1-down|TFPI-down THBS1-down	CFH-up_3075 CCND1-up_595|PLAU-up_5328 CCND1-up_595|SERPINE1-down_5054 CCND1-up_595|CFH-up_3075 MMP2-up_4313|CFH-up_3075 THBS1-down_7057|F3-down_2152 HBEGF-down_1839|F3-down_2152 MMP2-up_4313|F3-down_2152 THBS1-down_7057|PLAU-up_5328 HBEGF-down_1839|SERPINE1-down_5054 HBEGF-down_1839|PLAU-up_5328 MMP1-up_4312|SERPINE1-down_5054 MMP1-up_4312|TFPI-down_7035 MMP1-up_4312|PLAU-up_5328 MMP2-up_4313|SERPIND1-up_3053 MMP2-up_4313|SERPINE1-down_5054 MMP2-up_4313|TFPI-down_7035 MMP2-up_4313|PLAU-up_5328 THBS1-down_7057|SERPINE1-down_5054 THBS1-down_7057|TFPI-down_7035 THBS1-down_7057
hsa04610	hsa05323	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CFH-up FLT1-down|CFH-up JUN-down|SERPINE1-down CTSK-up|F3-down CXCL12-up|PLAU-up CXCL12-up|SERPINE1-down CXCL12-up|TFPI-down CXCL12-up|F3-down FLT1-down|F3-down JUN-down|PLAU-up FLT1-down|SERPINE1-down FLT1-down|TFPI-down FLT1-down|PLAU-up JUN-down|SERPINE1-down JUN-down|TFPI-down JUN-down|PLAU-up MMP1-up|SERPINE1-down MMP1-up|TFPI-down MMP1-up|PLAU-up TGFB3-up|SERPINE1-down TGFB3-up	CFH-up_3075 FLT1-down_2321|CFH-up_3075 JUN-down_3725|SERPINE1-down_5054 CTSK-up_1513|F3-down_2152 CXCL12-up_6387|PLAU-up_5328 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|TFPI-down_7035 CXCL12-up_6387|F3-down_2152 FLT1-down_2321|F3-down_2152 JUN-down_3725|PLAU-up_5328 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|TFPI-down_7035 FLT1-down_2321|PLAU-up_5328 JUN-down_3725|SERPINE1-down_5054 JUN-down_3725|TFPI-down_7035 JUN-down_3725|PLAU-up_5328 MMP1-up_4312|SERPINE1-down_5054 MMP1-up_4312|TFPI-down_7035 MMP1-up_4312|PLAU-up_5328 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04610	hsa05414	Complement and coagulation cascades - Homo sapiens (human)	F3,SERPINE1,TFPI,C6,C7,CFH,MASP1,PLAU,SERPIND1	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.035	SERPINE1-down ADRB1-down|TFPI-down ADRB1-down|CFH-up IGF1-up|F3-down IGF1-up|SERPINE1-down IGF1-up|PLAU-up ITGB4-up|PLAU-up TGFB3-up|SERPINE1-down TGFB3-up	SERPINE1-down_5054 ADRB1-down_153|TFPI-down_7035 ADRB1-down_153|CFH-up_3075 IGF1-up_3479|F3-down_2152 IGF1-up_3479|SERPINE1-down_5054 IGF1-up_3479|PLAU-up_5328 ITGB4-up_3691|PLAU-up_5328 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04630	hsa04668	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	0.003	CCND1-up JUN-down|CCND1-up MAP3K8-down|CCND1-up VCAM1-up|CCND2-up CXCL2-down|CCND2-up JUN-down|CCND2-up MAP3K8-down|CSF3R-down JUN-down|CSF3R-down SOCS3-down|JAK1-down JUN-down|JAK1-down SOCS3-down|JAK1-down VCAM1-up|LIFR-down JUN-down|MCL1-down JUN-down|LIFR-down SOCS3-down|LIFR-down VCAM1-up|MCL1-down MAP3K8-down|MCL1-down SOCS3-down|MCL1-down VCAM1-up	CCND1-up_595 JUN-down_3725|CCND1-up_595 MAP3K8-down_1326|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL2-down_2920|CCND2-up_894 JUN-down_3725|CCND2-up_894 MAP3K8-down_1326|CSF3R-down_1441 JUN-down_3725|CSF3R-down_1441 SOCS3-down_9021|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 SOCS3-down_9021|JAK1-down_3716 VCAM1-up_7412|LIFR-down_3977 JUN-down_3725|MCL1-down_4170 JUN-down_3725|LIFR-down_3977 SOCS3-down_9021|LIFR-down_3977 VCAM1-up_7412|MCL1-down_4170 MAP3K8-down_1326|MCL1-down_4170 SOCS3-down_9021|MCL1-down_4170 VCAM1-up_7412
hsa04630	hsa04670	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	0.003	CCND1-up CXCL12-up|CCND1-up MMP2-up|CCND1-up VCAM1-up|CCND2-up CXCL12-up|CCND2-up MMP2-up|CSF3R-down CXCL12-up|JAK1-down CXCL12-up|LIFR-down CXCL12-up|MCL1-down CXCL12-up|SOCS3-down CXCL12-up|JAK1-down MMP2-up|JAK1-down VCAM1-up|LIFR-down VCAM1-up|MCL1-down MMP2-up|MCL1-down VCAM1-up|SOCS3-down MMP2-up|SOCS3-down VCAM1-up	CCND1-up_595 CXCL12-up_6387|CCND1-up_595 MMP2-up_4313|CCND1-up_595 VCAM1-up_7412|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 MMP2-up_4313|CSF3R-down_1441 CXCL12-up_6387|JAK1-down_3716 CXCL12-up_6387|LIFR-down_3977 CXCL12-up_6387|MCL1-down_4170 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 VCAM1-up_7412|LIFR-down_3977 VCAM1-up_7412|MCL1-down_4170 MMP2-up_4313|MCL1-down_4170 VCAM1-up_7412|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 VCAM1-up_7412
hsa04630	hsa04915	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0.002	CCND1-up HBEGF-down|CCND1-up HSPA1A-down|CCND1-up JUN-down|CCND1-up MMP2-up|CCND2-up HBEGF-down|CCND2-up JUN-down|CCND2-up MMP2-up|CSF3R-down JUN-down|JAK1-down GABBR2-up|LIFR-down HBEGF-down|MCL1-down HBEGF-down|SOCS3-down HBEGF-down|JAK1-down HSPA1A-down|JAK1-down HSPA1B-down|JAK1-down JUN-down|JAK1-down MMP2-up|LIFR-down JUN-down|MCL1-down JUN-down|SOCS3-down JUN-down|MCL1-down MMP2-up|SOCS3-down MMP2-up	CCND1-up_595 HBEGF-down_1839|CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP2-up_4313|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP2-up_4313|CSF3R-down_1441 JUN-down_3725|JAK1-down_3716 GABBR2-up_9568|LIFR-down_3977 HBEGF-down_1839|MCL1-down_4170 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 HSPA1A-down_3303|JAK1-down_3716 HSPA1B-down_3304|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP2-up_4313|LIFR-down_3977 JUN-down_3725|MCL1-down_4170 JUN-down_3725|SOCS3-down_9021 JUN-down_3725|MCL1-down_4170 MMP2-up_4313|SOCS3-down_9021 MMP2-up_4313
hsa04630	hsa04978	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.005	CCND1-up HMOX1-down|CCND1-up TF-up|CCND2-up HMOX1-down|CCND2-up TF-up|JAK1-down HMOX1-down|MCL1-down HMOX1-down|SOCS3-down HMOX1-down|JAK1-down TF-up|MCL1-down MT1E-down|MCL1-down TF-up|SOCS3-down TF-up	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|CCND2-up_894 HMOX1-down_3162|CCND2-up_894 TF-up_7018|JAK1-down_3716 HMOX1-down_3162|MCL1-down_4170 HMOX1-down_3162|SOCS3-down_9021 HMOX1-down_3162|JAK1-down_3716 TF-up_7018|MCL1-down_4170 MT1E-down_4493|MCL1-down_4170 TF-up_7018|SOCS3-down_9021 TF-up_7018
hsa04630	hsa05146	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.015	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up LAMA3-down|CCND1-up TGFB3-up|CCND2-up COL1A2-up|CCND2-up COL3A1-up|CCND2-up TGFB3-up|SOCS3-down COL1A1-up|JAK1-down COL1A2-up|SOCS3-down IL1R2-down|MCL1-down SERPINB3-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 COL1A2-up_1278|CCND2-up_894 COL3A1-up_1281|CCND2-up_894 TGFB3-up_7043|SOCS3-down_9021 COL1A1-up_1277|JAK1-down_3716 COL1A2-up_1278|SOCS3-down_9021 IL1R2-down_7850|MCL1-down_4170 SERPINB3-up_6317
hsa04630	hsa05202	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up JAK1-down|CCND2-up MCL1-down|CCND2-up SOCS3-down|JAK1-down FLT1-down|MCL1-down FLT1-down|SOCS3-down FLT1-down|JAK1-down IGF1-up|LIFR-down IGF1-up|MCL1-down IGF1-up|SOCS3-down IGF1-up|SOCS3-down IL1R2-down|JAK1-down PLAU-up|JAK1-down ZBTB16-down|MCL1-down NFKBIZ-down|MCL1-down PROM1-up|MCL1-down ZBTB16-down|SOCS3-down NFKBIZ-down|SOCS3-down PLAU-up	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 JAK1-down_3716|CCND2-up_894 MCL1-down_4170|CCND2-up_894 SOCS3-down_9021|JAK1-down_3716 FLT1-down_2321|MCL1-down_4170 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|JAK1-down_3716 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|MCL1-down_4170 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|SOCS3-down_9021 IL1R2-down_7850|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|MCL1-down_4170 NFKBIZ-down_64332|MCL1-down_4170 PROM1-up_8842|MCL1-down_4170 ZBTB16-down_7704|SOCS3-down_9021 NFKBIZ-down_64332|SOCS3-down_9021 PLAU-up_5328
hsa04630	hsa05323	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up FLT1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|CSF3R-down CXCL12-up|CSF3R-down JUN-down|MCL1-down CTSK-up|SOCS3-down CTSK-up|JAK1-down CXCL12-up|LIFR-down CXCL12-up|MCL1-down CXCL12-up|SOCS3-down CXCL12-up|JAK1-down FLT1-down|MCL1-down FLT1-down|SOCS3-down FLT1-down|JAK1-down JUN-down|JAK1-down MMP1-up|LIFR-down JUN-down|MCL1-down JUN-down|SOCS3-down JUN-down|MCL1-down MMP1-up|SOCS3-down MMP1-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|CSF3R-down_1441 CXCL12-up_6387|CSF3R-down_1441 JUN-down_3725|MCL1-down_4170 CTSK-up_1513|SOCS3-down_9021 CTSK-up_1513|JAK1-down_3716 CXCL12-up_6387|LIFR-down_3977 CXCL12-up_6387|MCL1-down_4170 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|JAK1-down_3716 FLT1-down_2321|MCL1-down_4170 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP1-up_4312|LIFR-down_3977 JUN-down_3725|MCL1-down_4170 JUN-down_3725|SOCS3-down_9021 JUN-down_3725|MCL1-down_4170 MMP1-up_4312|SOCS3-down_9021 MMP1-up_4312
hsa04630	hsa05410	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.003	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|JAK1-down IGF1-up|LIFR-down IGF1-up|MCL1-down IGF1-up|SOCS3-down IGF1-up|MCL1-down ITGB4-up|MCL1-down ITGB8-up|MCL1-down PRKAA2-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|JAK1-down_3716 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|MCL1-down_4170 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|MCL1-down_4170 ITGB4-up_3691|MCL1-down_4170 ITGB8-up_3696|MCL1-down_4170 PRKAA2-up_5563
hsa04630	hsa05412	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.003	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|JAK1-down CDH2-up|MCL1-down CDH2-up|SOCS3-down CDH2-up|MCL1-down ITGB4-up|MCL1-down ITGB8-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|JAK1-down_3716 CDH2-up_1000|MCL1-down_4170 CDH2-up_1000|SOCS3-down_9021 CDH2-up_1000|MCL1-down_4170 ITGB4-up_3691|MCL1-down_4170 ITGB8-up_3696
hsa04630	hsa05414	Jak-STAT signaling pathway - Homo sapiens (human)	CSF3R,JAK1,LIFR,MCL1,SOCS3,CCND1,CCND2,IL13RA2	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.032	MCL1-down ADRB1-down|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up TGFB3-up|JAK1-down IGF1-up|LIFR-down IGF1-up|MCL1-down IGF1-up|SOCS3-down IGF1-up|MCL1-down ITGB4-up|MCL1-down ITGB8-up	MCL1-down_4170 ADRB1-down_153|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 TGFB3-up_7043|JAK1-down_3716 IGF1-up_3479|LIFR-down_3977 IGF1-up_3479|MCL1-down_4170 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|MCL1-down_4170 ITGB4-up_3691|MCL1-down_4170 ITGB8-up_3696
hsa04668	hsa04915	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	0	CXCL2-down HSPA1A-down|CXCL2-down JUN-down|CXCL2-down KCNJ5-up|CXCL2-down MMP2-up|CXCL3-down HBEGF-down|CXCL3-down JUN-down|CXCL3-down MMP2-up|MAP3K8-down HBEGF-down|SOCS3-down HBEGF-down|VCAM1-up HBEGF-down|IL18R1-down JUN-down|SOCS3-down MMP2-up|VCAM1-up MMP2-up	CXCL2-down_2920 HSPA1A-down_3303|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 KCNJ5-up_3762|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|MAP3K8-down_1326 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|IL18R1-down_8809 JUN-down_3725|SOCS3-down_9021 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313
hsa04668	hsa04970	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	0.002	MAP3K8-down ADRB1-down|JUN-down AQP5-up|CXCL2-down MUC5B-up|CXCL3-down MUC5B-up|JUN-down GUCY1A3-up|IL18R1-down MUC5B-up|JUN-down KCNMA1-up|JUN-down KCNN4-up|JUN-down MUC5B-up|SOCS3-down MUC5B-up|VCAM1-up MUC5B-up	MAP3K8-down_1326 ADRB1-down_153|JUN-down_3725 AQP5-up_362|CXCL2-down_2920 MUC5B-up_727897|CXCL3-down_2921 MUC5B-up_727897|JUN-down_3725 GUCY1A3-up_2982|IL18R1-down_8809 MUC5B-up_727897|JUN-down_3725 KCNMA1-up_3778|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MUC5B-up_727897|SOCS3-down_9021 MUC5B-up_727897|VCAM1-up_7412 MUC5B-up_727897
hsa04668	hsa05146	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.002	CXCL2-down COL1A1-up|JUN-down COL1A1-up|SOCS3-down COL1A1-up|VCAM1-up COL1A1-up|JUN-down COL1A2-up|JUN-down COL3A1-up|CXCL2-down IL1R2-down|IL18R1-down IL1R2-down|SOCS3-down IL1R2-down|JUN-down LAMA3-down|JUN-down SERPINB3-up|JUN-down TGFB3-up|VCAM1-up LAMA3-down|VCAM1-up TGFB3-up	CXCL2-down_2920 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|SOCS3-down_9021 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|JUN-down_3725 COL3A1-up_1281|CXCL2-down_2920 IL1R2-down_7850|IL18R1-down_8809 IL1R2-down_7850|SOCS3-down_9021 IL1R2-down_7850|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SERPINB3-up_6317|JUN-down_3725 TGFB3-up_7043|VCAM1-up_7412 LAMA3-down_3909|VCAM1-up_7412 TGFB3-up_7043
hsa04668	hsa05152	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0	IL18R1-down CD74-up|JUN-down CD74-up|SOCS3-down CD74-up|VCAM1-up CD74-up|SOCS3-down CLEC4E-down|JUN-down JAK1-down|SOCS3-down JAK1-down|VCAM1-up JAK1-down|JUN-down TGFB3-up|VCAM1-up TGFB3-up	IL18R1-down_8809 CD74-up_972|JUN-down_3725 CD74-up_972|SOCS3-down_9021 CD74-up_972|VCAM1-up_7412 CD74-up_972|SOCS3-down_9021 CLEC4E-down_26253|JUN-down_3725 JAK1-down_3716|SOCS3-down_9021 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|JUN-down_3725 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04668	hsa05168	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	IL18R1-down CD74-up|VCAM1-up CD74-up|CXCL2-down JUN-down|CXCL2-down SOCS3-down|CXCL3-down JUN-down|CXCL3-down SOCS3-down|IL18R1-down JUN-down|IL18R1-down SOCS3-down|VCAM1-up JAK1-down|MAP3K8-down SOCS3-down	IL18R1-down_8809 CD74-up_972|VCAM1-up_7412 CD74-up_972|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 SOCS3-down_9021|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 SOCS3-down_9021|IL18R1-down_8809 JUN-down_3725|IL18R1-down_8809 SOCS3-down_9021|VCAM1-up_7412 JAK1-down_3716|MAP3K8-down_1326 SOCS3-down_9021
hsa04668	hsa05200	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.001	MAP3K8-down CCND1-up|SOCS3-down CCND1-up|VCAM1-up CCND1-up|SOCS3-down CSF3R-down|CXCL2-down CXCL12-up|CXCL3-down CXCL12-up|SOCS3-down CXCL12-up|VCAM1-up CXCL12-up|CXCL2-down IGF1-up|CXCL2-down JUN-down|CXCL2-down MMP1-up|CXCL2-down MMP2-up|CXCL3-down JUN-down|CXCL3-down MMP2-up|MAP3K8-down DAPK2-down|VCAM1-up EDNRB-down|VCAM1-up FIGF-down|MAP3K8-down FZD5-down|IL18R1-down IGF1-up|MAP3K8-down IGF1-up|SOCS3-down IGF1-up|VCAM1-up IGF1-up|IL18R1-down JUN-down|SOCS3-down JAK1-down|VCAM1-up JAK1-down|VCAM1-up LAMA3-down|MAP3K8-down PDGFRA-down|MAP3K8-down ZBTB16-down|SOCS3-down MMP1-up|VCAM1-up MMP1-up|SOCS3-down MMP2-up|VCAM1-up MMP2-up|SOCS3-down PDGFRA-down|VCAM1-up PDGFRA-down|VCAM1-up TGFB3-up	MAP3K8-down_1326 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|SOCS3-down_9021 CSF3R-down_1441|CXCL2-down_2920 CXCL12-up_6387|CXCL3-down_2921 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|VCAM1-up_7412 CXCL12-up_6387|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 JUN-down_3725|CXCL3-down_2921 MMP2-up_4313|MAP3K8-down_1326 DAPK2-down_23604|VCAM1-up_7412 EDNRB-down_1910|VCAM1-up_7412 FIGF-down_2277|MAP3K8-down_1326 FZD5-down_7855|IL18R1-down_8809 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|IL18R1-down_8809 JUN-down_3725|SOCS3-down_9021 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|VCAM1-up_7412 LAMA3-down_3909|MAP3K8-down_1326 PDGFRA-down_5156|MAP3K8-down_1326 ZBTB16-down_7704|SOCS3-down_9021 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|SOCS3-down_9021 PDGFRA-down_5156|VCAM1-up_7412 PDGFRA-down_5156|VCAM1-up_7412 TGFB3-up_7043
hsa04668	hsa05202	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	CXCL2-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|SOCS3-down CCND2-up|CXCL2-down IGF1-up|CXCL2-down IL1R2-down|CXCL2-down PLAU-up|CXCL3-down PLAU-up|JUN-down FLT1-down|SOCS3-down FLT1-down|VCAM1-up FLT1-down|IL18R1-down IGF1-up|JUN-down IGF1-up|MAP3K8-down IGF1-up|SOCS3-down IGF1-up|VCAM1-up IGF1-up|IL18R1-down IL1R2-down|SOCS3-down IL1R2-down|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|MAP3K8-down NFKBIZ-down|MAP3K8-down PLAU-up|MAP3K8-down ZBTB16-down|SOCS3-down NFKBIZ-down|SOCS3-down PLAU-up|VCAM1-up PLAU-up|VCAM1-up PROM1-up	CXCL2-down_2920 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 IL1R2-down_7850|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 PLAU-up_5328|JUN-down_3725 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|IL18R1-down_8809 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|IL18R1-down_8809 IL1R2-down_7850|SOCS3-down_9021 IL1R2-down_7850|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|MAP3K8-down_1326 NFKBIZ-down_64332|MAP3K8-down_1326 PLAU-up_5328|MAP3K8-down_1326 ZBTB16-down_7704|SOCS3-down_9021 NFKBIZ-down_64332|SOCS3-down_9021 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|VCAM1-up_7412 PROM1-up_8842
hsa04668	hsa05205	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	JUN-down CAV2-down|JUN-down CCND1-up|MAP3K8-down CCND1-up|SOCS3-down CCND1-up|VCAM1-up CCND1-up|CXCL2-down IGF1-up|CXCL2-down MMP2-up|CXCL2-down PLAU-up|CXCL3-down HBEGF-down|CXCL3-down MMP2-up|CXCL3-down PLAU-up|JUN-down FLNC-up|VCAM1-up FLNC-up|JUN-down FZD5-down|MAP3K8-down FZD5-down|JUN-down HBEGF-down|MAP3K8-down HBEGF-down|SOCS3-down HBEGF-down|VCAM1-up HBEGF-down|IL18R1-down IGF1-up|JUN-down IGF1-up|MAP3K8-down IGF1-up|SOCS3-down IGF1-up|VCAM1-up IGF1-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|MAP3K8-down PLAU-up|SOCS3-down MMP2-up|VCAM1-up MMP2-up|SOCS3-down PLAU-up|VCAM1-up PLAU-up|SOCS3-down THBS1-down|VCAM1-up THBS1-down	JUN-down_3725 CAV2-down_858|JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL2-down_2920 IGF1-up_3479|CXCL2-down_2920 MMP2-up_4313|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 MMP2-up_4313|CXCL3-down_2921 PLAU-up_5328|JUN-down_3725 FLNC-up_2318|VCAM1-up_7412 FLNC-up_2318|JUN-down_3725 FZD5-down_7855|MAP3K8-down_1326 FZD5-down_7855|JUN-down_3725 HBEGF-down_1839|MAP3K8-down_1326 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|IL18R1-down_8809 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|MAP3K8-down_1326 PLAU-up_5328|SOCS3-down_9021 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|SOCS3-down_9021 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04668	hsa05206	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	JUN-down CCND1-up|MAP3K8-down CCND1-up|SOCS3-down CCND1-up|VCAM1-up CCND1-up|CXCL2-down CCND2-up|JUN-down CCND2-up|MAP3K8-down CCND2-up|SOCS3-down CCND2-up|CXCL2-down CYP24A1-up|CXCL2-down IRS2-down|CXCL2-down PLAU-up|CXCL3-down PLAU-up|JUN-down CYP24A1-up|SOCS3-down CYP24A1-up|JUN-down HMOX1-down|SOCS3-down HMOX1-down|VCAM1-up HMOX1-down|JUN-down IRS2-down|SOCS3-down IRS2-down|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|MAP3K8-down MCL1-down|MAP3K8-down PDGFRA-down|MAP3K8-down PLAU-up|SOCS3-down MCL1-down|VCAM1-up MCL1-down|SOCS3-down PDGFRA-down|VCAM1-up PDGFRA-down|SOCS3-down PLAU-up|VCAM1-up PLAU-up|SOCS3-down THBS1-down|SOCS3-down TNC-up|VCAM1-up THBS1-down|VCAM1-up TNC-up	JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL2-down_2920 CCND2-up_894|JUN-down_3725 CCND2-up_894|MAP3K8-down_1326 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CXCL2-down_2920 CYP24A1-up_1591|CXCL2-down_2920 IRS2-down_8660|CXCL2-down_2920 PLAU-up_5328|CXCL3-down_2921 PLAU-up_5328|JUN-down_3725 CYP24A1-up_1591|SOCS3-down_9021 CYP24A1-up_1591|JUN-down_3725 HMOX1-down_3162|SOCS3-down_9021 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|JUN-down_3725 IRS2-down_8660|SOCS3-down_9021 IRS2-down_8660|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|MAP3K8-down_1326 MCL1-down_4170|MAP3K8-down_1326 PDGFRA-down_5156|MAP3K8-down_1326 PLAU-up_5328|SOCS3-down_9021 MCL1-down_4170|VCAM1-up_7412 MCL1-down_4170|SOCS3-down_9021 PDGFRA-down_5156|VCAM1-up_7412 PDGFRA-down_5156|SOCS3-down_9021 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057|SOCS3-down_9021 TNC-up_3371|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 TNC-up_3371
hsa04668	hsa05219	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.001	JUN-down CCND1-up|MAP3K8-down CCND1-up|SOCS3-down CCND1-up|VCAM1-up CCND1-up|CXCL2-down MMP1-up|CXCL2-down MMP2-up|CXCL3-down HBEGF-down|CXCL3-down MMP2-up|MAP3K8-down DAPK2-down|JUN-down HBEGF-down|MAP3K8-down HBEGF-down|SOCS3-down HBEGF-down|VCAM1-up HBEGF-down|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|SOCS3-down MMP1-up|VCAM1-up MMP1-up|SOCS3-down MMP2-up|VCAM1-up MMP2-up|SOCS3-down THBS1-down|VCAM1-up THBS1-down	JUN-down_3725 CCND1-up_595|MAP3K8-down_1326 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL2-down_2920 MMP1-up_4312|CXCL2-down_2920 MMP2-up_4313|CXCL3-down_2921 HBEGF-down_1839|CXCL3-down_2921 MMP2-up_4313|MAP3K8-down_1326 DAPK2-down_23604|JUN-down_3725 HBEGF-down_1839|MAP3K8-down_1326 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|SOCS3-down_9021 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|SOCS3-down_9021 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04668	hsa05323	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	SOCS3-down CTSK-up|VCAM1-up CTSK-up|CXCL2-down CXCL12-up|CXCL3-down CXCL12-up|SOCS3-down CXCL12-up|VCAM1-up CXCL12-up|CXCL2-down JUN-down|CXCL2-down MMP1-up|CXCL3-down JUN-down|SOCS3-down FLT1-down|VCAM1-up FLT1-down|IL18R1-down JUN-down|SOCS3-down MMP1-up|VCAM1-up MMP1-up|VCAM1-up TGFB3-up	SOCS3-down_9021 CTSK-up_1513|VCAM1-up_7412 CTSK-up_1513|CXCL2-down_2920 CXCL12-up_6387|CXCL3-down_2921 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|VCAM1-up_7412 CXCL12-up_6387|CXCL2-down_2920 JUN-down_3725|CXCL2-down_2920 MMP1-up_4312|CXCL3-down_2921 JUN-down_3725|SOCS3-down_9021 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|IL18R1-down_8809 JUN-down_3725|SOCS3-down_9021 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|VCAM1-up_7412 TGFB3-up_7043
hsa04668	hsa05410	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.038	CXCL2-down IGF1-up|IL18R1-down IGF1-up|JUN-down IGF1-up|MAP3K8-down IGF1-up|SOCS3-down IGF1-up|VCAM1-up IGF1-up|JUN-down ITGB4-up|VCAM1-up ITGB4-up|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|MAP3K8-down PRKAA2-up|MAP3K8-down TNNC1-down|VCAM1-up TGFB3-up	CXCL2-down_2920 IGF1-up_3479|IL18R1-down_8809 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MAP3K8-down_1326 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MAP3K8-down_1326 PRKAA2-up_5563|MAP3K8-down_1326 TNNC1-down_7134|VCAM1-up_7412 TGFB3-up_7043
hsa04668	hsa05412	TNF signaling pathway - Homo sapiens (human)	CXCL2,CXCL3,IL18R1,JUN,MAP3K8,SOCS3,VCAM1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.047	IL18R1-down CDH2-up|JUN-down CDH2-up|MAP3K8-down CDH2-up|SOCS3-down CDH2-up|VCAM1-up CDH2-up|JUN-down ITGB4-up|VCAM1-up ITGB4-up|JUN-down TCF7L2-up	IL18R1-down_8809 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|MAP3K8-down_1326 CDH2-up_1000|SOCS3-down_9021 CDH2-up_1000|VCAM1-up_7412 CDH2-up_1000|JUN-down_3725 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|JUN-down_3725 TCF7L2-up_6934
hsa04670	hsa04933	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	0.003	CXCL12-up CCND1-up|CLDN1-up COL1A1-up|CLDN1-up COL1A2-up|CLDN1-up COL3A1-up|CLDN1-up MMP2-up|CLDN5-down FIGF-down|CLDN5-down JUN-down|CLDN5-down MMP2-up|CLDN5-down SERPINE1-down|CLDN5-down VCAM1-up|CXCL12-up COL1A1-up|THY1-up COL1A1-up|CXCL12-up COL1A2-up|CXCL12-up COL3A1-up|CXCL12-up F3-down|CXCL12-up FIGF-down|CXCL12-up JUN-down|CXCL12-up MMP2-up|CXCL12-up SERPINE1-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|THY1-up JUN-down|THY1-up SERPINE1-down|THY1-up TGFB3-up|THY1-up VCAM1-up	CXCL12-up_6387 CCND1-up_595|CLDN1-up_9076 COL1A1-up_1277|CLDN1-up_9076 COL1A2-up_1278|CLDN1-up_9076 COL3A1-up_1281|CLDN1-up_9076 MMP2-up_4313|CLDN5-down_7122 FIGF-down_2277|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 SERPINE1-down_5054|CLDN5-down_7122 VCAM1-up_7412|CXCL12-up_6387 COL1A1-up_1277|THY1-up_7070 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|CXCL12-up_6387 F3-down_2152|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 SERPINE1-down_5054|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|THY1-up_7070 JUN-down_3725|THY1-up_7070 SERPINE1-down_5054|THY1-up_7070 TGFB3-up_7043|THY1-up_7070 VCAM1-up_7412
hsa04670	hsa04970	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	0.01	CLDN1-up AQP5-up|CLDN18-down AQP5-up|CLDN5-down AQP5-up|MMP2-up AQP5-up|MMP2-up MUC5B-up|VCAM1-up MUC5B-up	CLDN1-up_9076 AQP5-up_362|CLDN18-down_51208 AQP5-up_362|CLDN5-down_7122 AQP5-up_362|MMP2-up_4313 AQP5-up_362|MMP2-up_4313 MUC5B-up_727897|VCAM1-up_7412 MUC5B-up_727897
hsa04670	hsa04974	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CLDN1-up COL17A1-up|CLDN1-up COL1A1-up|CLDN1-up COL1A2-up|CLDN1-up COL3A1-up|THY1-up COL10A1-up|MMP2-up COL14A1-up|MMP2-up COL15A1-up|MMP2-up COL17A1-up|CXCL12-up COL18A1-up|MMP2-up COL18A1-up|VCAM1-up COL18A1-up|CXCL12-up COL1A1-up|MMP2-up COL1A1-up|THY1-up COL1A1-up|VCAM1-up COL1A1-up|CXCL12-up COL1A2-up|MMP2-up COL1A2-up|CXCL12-up COL3A1-up|MMP2-up COL3A1-up|MMP2-up COL5A1-up|MMP2-up COL5A2-up|MMP2-up COL6A1-up|MMP2-up COL6A3-up|MMP2-up COL7A1-up|CXCL12-up MME-down|MMP2-up MME-down|THY1-up MME-down|VCAM1-up MME-down	CLDN1-up_9076 COL17A1-up_1308|CLDN1-up_9076 COL1A1-up_1277|CLDN1-up_9076 COL1A2-up_1278|CLDN1-up_9076 COL3A1-up_1281|THY1-up_7070 COL10A1-up_1300|MMP2-up_4313 COL14A1-up_7373|MMP2-up_4313 COL15A1-up_1306|MMP2-up_4313 COL17A1-up_1308|CXCL12-up_6387 COL18A1-up_80781|MMP2-up_4313 COL18A1-up_80781|VCAM1-up_7412 COL18A1-up_80781|CXCL12-up_6387 COL1A1-up_1277|MMP2-up_4313 COL1A1-up_1277|THY1-up_7070 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|MMP2-up_4313 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|MMP2-up_4313 COL3A1-up_1281|MMP2-up_4313 COL5A1-up_1289|MMP2-up_4313 COL5A2-up_1290|MMP2-up_4313 COL6A1-up_1291|MMP2-up_4313 COL6A3-up_1293|MMP2-up_4313 COL7A1-up_1294|CXCL12-up_6387 MME-down_4311|MMP2-up_4313 MME-down_4311|THY1-up_7070 MME-down_4311|VCAM1-up_7412 MME-down_4311
hsa04670	hsa04978	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0.003	CLDN5-down HMOX1-down|CLDN5-down TF-up|CXCL12-up HMOX1-down|CXCL12-up TF-up|MMP2-up HMOX1-down|VCAM1-up HMOX1-down|MMP2-up MT1E-down|MMP2-up TF-up|VCAM1-up MT2A-down|THY1-up TF-up|VCAM1-up TF-up	CLDN5-down_7122 HMOX1-down_3162|CLDN5-down_7122 TF-up_7018|CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 TF-up_7018|MMP2-up_4313 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|MMP2-up_4313 MT1E-down_4493|MMP2-up_4313 TF-up_7018|VCAM1-up_7412 MT2A-down_4502|THY1-up_7070 TF-up_7018|VCAM1-up_7412 TF-up_7018
hsa04670	hsa05145	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0	CLDN1-up LDLR-down|CXCL12-up JAK1-down|CXCL12-up LDLR-down|CXCL12-up TGFB3-up|MMP2-up JAK1-down|VCAM1-up JAK1-down|MMP2-up LAMA3-down|VCAM1-up LAMA3-down|MMP2-up LDLR-down|VCAM1-up LDLR-down|MMP2-up TGFB3-up|THY1-up TGFB3-up|VCAM1-up TGFB3-up	CLDN1-up_9076 LDLR-down_3949|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 LDLR-down_3949|CXCL12-up_6387 TGFB3-up_7043|MMP2-up_4313 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|MMP2-up_4313 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|MMP2-up_4313 LDLR-down_3949|VCAM1-up_7412 LDLR-down_3949|MMP2-up_4313 TGFB3-up_7043|THY1-up_7070 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04670	hsa05146	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	CLDN1-up COL1A1-up|CLDN1-up COL1A2-up|CLDN1-up COL3A1-up|CXCL12-up COL1A1-up|MMP2-up COL1A1-up|THY1-up COL1A1-up|VCAM1-up COL1A1-up|CXCL12-up COL1A2-up|MMP2-up COL1A2-up|CXCL12-up COL3A1-up|MMP2-up COL3A1-up|CXCL12-up TGFB3-up|MMP2-up LAMA3-down|VCAM1-up LAMA3-down|MMP2-up SERPINB3-up|MMP2-up TGFB3-up|THY1-up SERPINB3-up|THY1-up TGFB3-up|VCAM1-up TGFB3-up	CLDN1-up_9076 COL1A1-up_1277|CLDN1-up_9076 COL1A2-up_1278|CLDN1-up_9076 COL3A1-up_1281|CXCL12-up_6387 COL1A1-up_1277|MMP2-up_4313 COL1A1-up_1277|THY1-up_7070 COL1A1-up_1277|VCAM1-up_7412 COL1A1-up_1277|CXCL12-up_6387 COL1A2-up_1278|MMP2-up_4313 COL1A2-up_1278|CXCL12-up_6387 COL3A1-up_1281|MMP2-up_4313 COL3A1-up_1281|CXCL12-up_6387 TGFB3-up_7043|MMP2-up_4313 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|MMP2-up_4313 SERPINB3-up_6317|MMP2-up_4313 TGFB3-up_7043|THY1-up_7070 SERPINB3-up_6317|THY1-up_7070 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04670	hsa05152	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0	CXCL12-up CD74-up|MMP2-up CD74-up|VCAM1-up CD74-up|CXCL12-up JAK1-down|CXCL12-up TGFB3-up|MMP2-up JAK1-down|VCAM1-up JAK1-down|MMP2-up TGFB3-up|THY1-up TGFB3-up|VCAM1-up TGFB3-up	CXCL12-up_6387 CD74-up_972|MMP2-up_4313 CD74-up_972|VCAM1-up_7412 CD74-up_972|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 TGFB3-up_7043|MMP2-up_4313 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|MMP2-up_4313 TGFB3-up_7043|THY1-up_7070 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04670	hsa05166	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.009	CXCL12-up CCND1-up|MMP2-up CCND1-up|CXCL12-up CCND2-up|MMP2-up CCND2-up|CLDN1-up MYB-up|CLDN5-down JUN-down|CLDN5-down MYB-up|CLDN5-down VCAM1-up|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up MYB-up|CXCL12-up PDGFRA-down|CXCL12-up TGFB3-up|CXCL12-up VCAM1-up|MMP2-up JAK1-down|MMP2-up JUN-down|THY1-up JUN-down|MMP2-up MYB-up|MMP2-up PDGFRA-down|MMP2-up TGFB3-up|MMP2-up VCAM1-up|THY1-up MYB-up|THY1-up TGFB3-up|THY1-up VCAM1-up	CXCL12-up_6387 CCND1-up_595|MMP2-up_4313 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|MMP2-up_4313 CCND2-up_894|CLDN1-up_9076 MYB-up_4602|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MYB-up_4602|CLDN5-down_7122 VCAM1-up_7412|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 MYB-up_4602|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 TGFB3-up_7043|CXCL12-up_6387 VCAM1-up_7412|MMP2-up_4313 JAK1-down_3716|MMP2-up_4313 JUN-down_3725|THY1-up_7070 JUN-down_3725|MMP2-up_4313 MYB-up_4602|MMP2-up_4313 PDGFRA-down_5156|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 VCAM1-up_7412|THY1-up_7070 MYB-up_4602|THY1-up_7070 TGFB3-up_7043|THY1-up_7070 VCAM1-up_7412
hsa04670	hsa05168	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	CXCL12-up CD74-up|MMP2-up CD74-up|VCAM1-up CD74-up|CLDN5-down JUN-down|CXCL12-up JAK1-down|CXCL12-up JUN-down|CXCL12-up SOCS3-down|MMP2-up JAK1-down|VCAM1-up JAK1-down|MMP2-up JUN-down|THY1-up JUN-down|VCAM1-up JUN-down|MMP2-up SOCS3-down|VCAM1-up SOCS3-down	CXCL12-up_6387 CD74-up_972|MMP2-up_4313 CD74-up_972|VCAM1-up_7412 CD74-up_972|CLDN5-down_7122 JUN-down_3725|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 JUN-down_3725|CXCL12-up_6387 SOCS3-down_9021|MMP2-up_4313 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|MMP2-up_4313 JUN-down_3725|THY1-up_7070 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|MMP2-up_4313 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04670	hsa05202	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.003	CXCL12-up CCND2-up|MMP2-up CCND2-up|CLDN1-up PLAU-up|CLDN5-down FLT1-down|CLDN5-down IGF1-up|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up PLAU-up|CXCL12-up PROM1-up|CXCL12-up ZBTB16-down|MMP2-up FLT1-down|VCAM1-up FLT1-down|MMP2-up IGF1-up|THY1-up IGF1-up|VCAM1-up IGF1-up|MMP2-up PLAU-up|MMP2-up PROM1-up|VCAM1-up PLAU-up|THY1-up PROM1-up|VCAM1-up PROM1-up	CXCL12-up_6387 CCND2-up_894|MMP2-up_4313 CCND2-up_894|CLDN1-up_9076 PLAU-up_5328|CLDN5-down_7122 FLT1-down_2321|CLDN5-down_7122 IGF1-up_3479|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 PROM1-up_8842|CXCL12-up_6387 ZBTB16-down_7704|MMP2-up_4313 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|MMP2-up_4313 IGF1-up_3479|THY1-up_7070 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 PROM1-up_8842|VCAM1-up_7412 PLAU-up_5328|THY1-up_7070 PROM1-up_8842|VCAM1-up_7412 PROM1-up_8842
hsa04670	hsa05205	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.004	CXCL12-up CCND1-up|VCAM1-up CCND1-up|CLDN1-up MMP2-up|CLDN1-up PLAU-up|CLDN1-up THBS1-down|CLDN5-down IGF1-up|CLDN5-down MMP2-up|CLDN5-down THBS1-down|CXCL12-up HBEGF-down|CXCL12-up IGF1-up|CXCL12-up MMP2-up|CXCL12-up PLAU-up|CXCL12-up THBS1-down|VCAM1-up FLNC-up|VCAM1-up HBEGF-down|THY1-up IGF1-up|VCAM1-up IGF1-up|VCAM1-up PLAU-up|THY1-up THBS1-down|VCAM1-up THBS1-down	CXCL12-up_6387 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 PLAU-up_5328|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 IGF1-up_3479|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 THBS1-down_7057|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 THBS1-down_7057|VCAM1-up_7412 FLNC-up_2318|VCAM1-up_7412 HBEGF-down_1839|THY1-up_7070 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|VCAM1-up_7412 PLAU-up_5328|THY1-up_7070 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04670	hsa05206	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CXCL12-up CCND1-up|MMP2-up CCND1-up|VCAM1-up CCND1-up|CXCL12-up CCND2-up|MMP2-up CCND2-up|CLDN18-down SERPINB5-up|CLDN1-up PLAU-up|CLDN1-up THBS1-down|CLDN5-down HMOX1-down|CLDN5-down THBS1-down|CXCL12-up HMOX1-down|CXCL12-up MCL1-down|CXCL12-up MMP16-up|CXCL12-up PDGFRA-down|CXCL12-up PLAU-up|CXCL12-up SERPINB5-up|CXCL12-up SOX4-up|CXCL12-up THBS1-down|CXCL12-up TNC-up|MMP2-up HMOX1-down|VCAM1-up HMOX1-down|MMP2-up MCL1-down|VCAM1-up MCL1-down|MMP2-up MMP16-up|MMP2-up PDGFRA-down|MMP2-up PLAU-up|MMP2-up SERPINB5-up|MMP2-up SOX4-up|MMP2-up THBS1-down|MMP2-up TNC-up|VCAM1-up PDGFRA-down|VCAM1-up PLAU-up|THY1-up SERPINB5-up|THY1-up THBS1-down|VCAM1-up THBS1-down|VCAM1-up TNC-up	CXCL12-up_6387 CCND1-up_595|MMP2-up_4313 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CXCL12-up_6387 CCND2-up_894|MMP2-up_4313 CCND2-up_894|CLDN18-down_51208 SERPINB5-up_5268|CLDN1-up_9076 PLAU-up_5328|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 HMOX1-down_3162|CLDN5-down_7122 THBS1-down_7057|CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MMP16-up_4325|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SOX4-up_6659|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 TNC-up_3371|MMP2-up_4313 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|MMP2-up_4313 MCL1-down_4170|VCAM1-up_7412 MCL1-down_4170|MMP2-up_4313 MMP16-up_4325|MMP2-up_4313 PDGFRA-down_5156|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 SERPINB5-up_5268|MMP2-up_4313 SOX4-up_6659|MMP2-up_4313 THBS1-down_7057|MMP2-up_4313 TNC-up_3371|VCAM1-up_7412 PDGFRA-down_5156|VCAM1-up_7412 PLAU-up_5328|THY1-up_7070 SERPINB5-up_5268|THY1-up_7070 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 TNC-up_3371
hsa04670	hsa05219	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.008	CXCL12-up CCND1-up|VCAM1-up CCND1-up|CLDN1-up MMP1-up|CLDN1-up MMP2-up|CLDN1-up THBS1-down|CLDN5-down MMP1-up|CLDN5-down MMP2-up|CLDN5-down THBS1-down|CXCL12-up HBEGF-down|CXCL12-up MMP1-up|CXCL12-up MMP2-up|CXCL12-up THBS1-down|VCAM1-up HBEGF-down|VCAM1-up MMP1-up|THY1-up THBS1-down|VCAM1-up THBS1-down	CXCL12-up_6387 CCND1-up_595|VCAM1-up_7412 CCND1-up_595|CLDN1-up_9076 MMP1-up_4312|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 MMP1-up_4312|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 THBS1-down_7057|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 MMP1-up_4312|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 THBS1-down_7057|VCAM1-up_7412 HBEGF-down_1839|VCAM1-up_7412 MMP1-up_4312|THY1-up_7070 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04670	hsa05323	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.004	CLDN1-up MMP1-up|CLDN5-down CXCL12-up|CLDN5-down FLT1-down|CLDN5-down JUN-down|CLDN5-down MMP1-up|MMP2-up CTSK-up|VCAM1-up CTSK-up|MMP2-up FLT1-down|VCAM1-up FLT1-down|MMP2-up JUN-down|THY1-up JUN-down|VCAM1-up JUN-down|MMP2-up MMP1-up|VCAM1-up MMP1-up|MMP2-up TGFB3-up|THY1-up TGFB3-up|VCAM1-up TGFB3-up	CLDN1-up_9076 MMP1-up_4312|CLDN5-down_7122 CXCL12-up_6387|CLDN5-down_7122 FLT1-down_2321|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MMP1-up_4312|MMP2-up_4313 CTSK-up_1513|VCAM1-up_7412 CTSK-up_1513|MMP2-up_4313 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|MMP2-up_4313 JUN-down_3725|THY1-up_7070 JUN-down_3725|VCAM1-up_7412 JUN-down_3725|MMP2-up_4313 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|MMP2-up_4313 TGFB3-up_7043|THY1-up_7070 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04670	hsa05410	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.001	CLDN1-up ITGB4-up|CLDN5-down IGF1-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|MMP2-up IGF1-up|THY1-up IGF1-up|VCAM1-up IGF1-up|MMP2-up ITGB4-up|THY1-up ITGB4-up|VCAM1-up ITGB4-up|MMP2-up TGFB3-up|MMP2-up TTN-down|THY1-up TGFB3-up|VCAM1-up TGFB3-up	CLDN1-up_9076 ITGB4-up_3691|CLDN5-down_7122 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|MMP2-up_4313 IGF1-up_3479|THY1-up_7070 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|MMP2-up_4313 ITGB4-up_3691|THY1-up_7070 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|THY1-up_7070 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04670	hsa05412	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CLDN1-up CDH2-up|CLDN5-down CDH2-up|CXCL12-up CDH2-up|MMP2-up CDH2-up|VCAM1-up CDH2-up|CLDN1-up ITGB4-up|CLDN1-up TCF7L2-up|CLDN5-down TCF7L2-up|MMP2-up ITGB4-up|THY1-up ITGB4-up|VCAM1-up ITGB4-up|MMP2-up TCF7L2-up	CLDN1-up_9076 CDH2-up_1000|CLDN5-down_7122 CDH2-up_1000|CXCL12-up_6387 CDH2-up_1000|MMP2-up_4313 CDH2-up_1000|VCAM1-up_7412 CDH2-up_1000|CLDN1-up_9076 ITGB4-up_3691|CLDN1-up_9076 TCF7L2-up_6934|CLDN5-down_7122 TCF7L2-up_6934|MMP2-up_4313 ITGB4-up_3691|THY1-up_7070 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|MMP2-up_4313 TCF7L2-up_6934
hsa04670	hsa05414	Leukocyte transendothelial migration - Homo sapiens (human)	CLDN18,CLDN5,CLDN1,CXCL12,MMP2,THY1,VCAM1	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.001	CLDN1-up ITGB4-up|CLDN5-down IGF1-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|MMP2-up IGF1-up|THY1-up IGF1-up|VCAM1-up IGF1-up|MMP2-up ITGB4-up|THY1-up ITGB4-up|VCAM1-up ITGB4-up|MMP2-up PLN-up|MMP2-up TGFB3-up|MMP2-up TTN-down|THY1-up TGFB3-up|VCAM1-up TGFB3-up	CLDN1-up_9076 ITGB4-up_3691|CLDN5-down_7122 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|MMP2-up_4313 IGF1-up_3479|THY1-up_7070 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|MMP2-up_4313 ITGB4-up_3691|THY1-up_7070 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|MMP2-up_4313 PLN-up_5350|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|THY1-up_7070 TGFB3-up_7043|VCAM1-up_7412 TGFB3-up_7043
hsa04915	hsa04970	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	0.016	HSPA1A-down AQP5-up|HSPA1B-down AQP5-up|JUN-down AQP5-up|MMP2-up AQP5-up|JUN-down GUCY1A3-up|HSPA1A-down MUC5B-up|JUN-down KCNMA1-up|JUN-down KCNN4-up|JUN-down MUC5B-up|KCNJ5-up KCNMA1-up|KCNJ5-up KCNN4-up|MMP2-up MUC5B-up	HSPA1A-down_3303 AQP5-up_362|HSPA1B-down_3304 AQP5-up_362|JUN-down_3725 AQP5-up_362|MMP2-up_4313 AQP5-up_362|JUN-down_3725 GUCY1A3-up_2982|HSPA1A-down_3303 MUC5B-up_727897|JUN-down_3725 KCNMA1-up_3778|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MUC5B-up_727897|KCNJ5-up_3762 KCNMA1-up_3778|KCNJ5-up_3762 KCNN4-up_3783|MMP2-up_4313 MUC5B-up_727897
hsa04915	hsa04974	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	JUN-down COL14A1-up|MMP2-up COL14A1-up|MMP2-up COL15A1-up|MMP2-up COL17A1-up|HBEGF-down COL18A1-up|JUN-down COL18A1-up|MMP2-up COL18A1-up|HSPA1A-down COL1A1-up|JUN-down COL1A1-up|MMP2-up COL1A1-up|JUN-down COL1A2-up|MMP2-up COL1A2-up|HSPA1A-down COL3A1-up|JUN-down COL3A1-up|MMP2-up COL3A1-up|JUN-down COL5A1-up|MMP2-up COL5A1-up|JUN-down COL5A2-up|MMP2-up COL5A2-up|JUN-down COL6A1-up|MMP2-up COL6A1-up|JUN-down COL6A3-up|MMP2-up COL6A3-up|HBEGF-down COL7A1-up|JUN-down COL7A1-up|MMP2-up COL7A1-up|HSPA1A-down MME-down|HSPA1B-down MME-down|JUN-down KCNN4-up|JUN-down MME-down|JUN-down PRSS1-up|KCNJ5-up KCNN4-up|MMP2-up MME-down	JUN-down_3725 COL14A1-up_7373|MMP2-up_4313 COL14A1-up_7373|MMP2-up_4313 COL15A1-up_1306|MMP2-up_4313 COL17A1-up_1308|HBEGF-down_1839 COL18A1-up_80781|JUN-down_3725 COL18A1-up_80781|MMP2-up_4313 COL18A1-up_80781|HSPA1A-down_3303 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|MMP2-up_4313 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|MMP2-up_4313 COL1A2-up_1278|HSPA1A-down_3303 COL3A1-up_1281|JUN-down_3725 COL3A1-up_1281|MMP2-up_4313 COL3A1-up_1281|JUN-down_3725 COL5A1-up_1289|MMP2-up_4313 COL5A1-up_1289|JUN-down_3725 COL5A2-up_1290|MMP2-up_4313 COL5A2-up_1290|JUN-down_3725 COL6A1-up_1291|MMP2-up_4313 COL6A1-up_1291|JUN-down_3725 COL6A3-up_1293|MMP2-up_4313 COL6A3-up_1293|HBEGF-down_1839 COL7A1-up_1294|JUN-down_3725 COL7A1-up_1294|MMP2-up_4313 COL7A1-up_1294|HSPA1A-down_3303 MME-down_4311|HSPA1B-down_3304 MME-down_4311|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MME-down_4311|JUN-down_3725 PRSS1-up_5644|KCNJ5-up_3762 KCNN4-up_3783|MMP2-up_4313 MME-down_4311
hsa04915	hsa04978	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0	GABBR2-up TF-up|HBEGF-down HMOX1-down|HBEGF-down TF-up|HSPA1A-down HMOX1-down|HSPA1B-down HMOX1-down|JUN-down HMOX1-down|MMP2-up HMOX1-down|HSPA1A-down MT2A-down|JUN-down MT1E-down|JUN-down MT1X-down|JUN-down MT2A-down|JUN-down TF-up|MMP2-up MT1E-down|MMP2-up TF-up	GABBR2-up_9568 TF-up_7018|HBEGF-down_1839 HMOX1-down_3162|HBEGF-down_1839 TF-up_7018|HSPA1A-down_3303 HMOX1-down_3162|HSPA1B-down_3304 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|MMP2-up_4313 HMOX1-down_3162|HSPA1A-down_3303 MT2A-down_4502|JUN-down_3725 MT1E-down_4493|JUN-down_3725 MT1X-down_4501|JUN-down_3725 MT2A-down_4502|JUN-down_3725 TF-up_7018|MMP2-up_4313 MT1E-down_4493|MMP2-up_4313 TF-up_7018
hsa04915	hsa05146	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.001	HSPA1A-down COL1A1-up|JUN-down COL1A1-up|MMP2-up COL1A1-up|JUN-down COL1A2-up|MMP2-up COL1A2-up|HSPA1A-down COL3A1-up|JUN-down COL3A1-up|MMP2-up COL3A1-up|HBEGF-down IL1R2-down|HBEGF-down LAMA3-down|HBEGF-down TGFB3-up|JUN-down LAMA3-down|JUN-down SERPINB3-up|JUN-down TGFB3-up|MMP2-up LAMA3-down|MMP2-up SERPINB3-up|MMP2-up TGFB3-up	HSPA1A-down_3303 COL1A1-up_1277|JUN-down_3725 COL1A1-up_1277|MMP2-up_4313 COL1A1-up_1277|JUN-down_3725 COL1A2-up_1278|MMP2-up_4313 COL1A2-up_1278|HSPA1A-down_3303 COL3A1-up_1281|JUN-down_3725 COL3A1-up_1281|MMP2-up_4313 COL3A1-up_1281|HBEGF-down_1839 IL1R2-down_7850|HBEGF-down_1839 LAMA3-down_3909|HBEGF-down_1839 TGFB3-up_7043|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SERPINB3-up_6317|JUN-down_3725 TGFB3-up_7043|MMP2-up_4313 LAMA3-down_3909|MMP2-up_4313 SERPINB3-up_6317|MMP2-up_4313 TGFB3-up_7043
hsa04915	hsa05152	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.009	JUN-down CD74-up|MMP2-up CD74-up|HSPA1A-down CLEC4E-down|GABBR2-up JAK1-down|HBEGF-down TGFB3-up|HSPA1A-down JAK1-down|HSPA1B-down JAK1-down|JUN-down JAK1-down|MMP2-up JAK1-down|JUN-down TGFB3-up|MMP2-up TGFB3-up	JUN-down_3725 CD74-up_972|MMP2-up_4313 CD74-up_972|HSPA1A-down_3303 CLEC4E-down_26253|GABBR2-up_9568 JAK1-down_3716|HBEGF-down_1839 TGFB3-up_7043|HSPA1A-down_3303 JAK1-down_3716|HSPA1B-down_3304 JAK1-down_3716|JUN-down_3725 JAK1-down_3716|MMP2-up_4313 JAK1-down_3716|JUN-down_3725 TGFB3-up_7043|MMP2-up_4313 TGFB3-up_7043
hsa04915	hsa05160	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0.005	MMP2-up CLDN1-up|JUN-down CLDN5-down|MMP2-up CLDN5-down|GABBR2-up JAK1-down|HBEGF-down SOCS3-down|HSPA1A-down JAK1-down|HSPA1A-down LDLR-down|HSPA1B-down JAK1-down|JUN-down JAK1-down|MMP2-up JAK1-down|JUN-down LDLR-down|JUN-down SOCS3-down|MMP2-up LDLR-down|MMP2-up SOCS3-down	MMP2-up_4313 CLDN1-up_9076|JUN-down_3725 CLDN5-down_7122|MMP2-up_4313 CLDN5-down_7122|GABBR2-up_9568 JAK1-down_3716|HBEGF-down_1839 SOCS3-down_9021|HSPA1A-down_3303 JAK1-down_3716|HSPA1A-down_3303 LDLR-down_3949|HSPA1B-down_3304 JAK1-down_3716|JUN-down_3725 JAK1-down_3716|MMP2-up_4313 JAK1-down_3716|JUN-down_3725 LDLR-down_3949|JUN-down_3725 SOCS3-down_9021|MMP2-up_4313 LDLR-down_3949|MMP2-up_4313 SOCS3-down_9021
hsa04915	hsa05166	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.001	HBEGF-down CCND1-up|HSPA1A-down CCND1-up|MMP2-up CCND1-up|HBEGF-down CCND2-up|MMP2-up CCND2-up|GABBR2-up FZD5-down|GABBR2-up JAK1-down|HBEGF-down IL1R2-down|HBEGF-down JUN-down|HBEGF-down PDGFRA-down|HBEGF-down TGFB3-up|HBEGF-down VCAM1-up|HSPA1A-down JAK1-down|HSPA1A-down JUN-down|HSPA1A-down PDGFRA-down|HSPA1B-down JAK1-down|HSPA1B-down JUN-down|HSPA1B-down PDGFRA-down|MMP2-up JAK1-down|MMP2-up MYB-up|MMP2-up PDGFRA-down|MMP2-up TGFB3-up|MMP2-up VCAM1-up	HBEGF-down_1839 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|MMP2-up_4313 CCND1-up_595|HBEGF-down_1839 CCND2-up_894|MMP2-up_4313 CCND2-up_894|GABBR2-up_9568 FZD5-down_7855|GABBR2-up_9568 JAK1-down_3716|HBEGF-down_1839 IL1R2-down_7850|HBEGF-down_1839 JUN-down_3725|HBEGF-down_1839 PDGFRA-down_5156|HBEGF-down_1839 TGFB3-up_7043|HBEGF-down_1839 VCAM1-up_7412|HSPA1A-down_3303 JAK1-down_3716|HSPA1A-down_3303 JUN-down_3725|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 JAK1-down_3716|HSPA1B-down_3304 JUN-down_3725|HSPA1B-down_3304 PDGFRA-down_5156|MMP2-up_4313 JAK1-down_3716|MMP2-up_4313 MYB-up_4602|MMP2-up_4313 PDGFRA-down_5156|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 VCAM1-up_7412
hsa04915	hsa05168	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.017	MMP2-up CD74-up|GABBR2-up JAK1-down|HBEGF-down JUN-down|HBEGF-down SOCS3-down|HSPA1A-down JAK1-down|HSPA1A-down JUN-down|HSPA1B-down JAK1-down|HSPA1B-down JUN-down|MMP2-up JAK1-down|MMP2-up SOCS3-down	MMP2-up_4313 CD74-up_972|GABBR2-up_9568 JAK1-down_3716|HBEGF-down_1839 JUN-down_3725|HBEGF-down_1839 SOCS3-down_9021|HSPA1A-down_3303 JAK1-down_3716|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JAK1-down_3716|HSPA1B-down_3304 JUN-down_3725|MMP2-up_4313 JAK1-down_3716|MMP2-up_4313 SOCS3-down_9021
hsa04915	hsa05202	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.011	HBEGF-down CCND2-up|JUN-down CCND2-up|MMP2-up CCND2-up|HBEGF-down FLT1-down|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JUN-down FLT1-down|MMP2-up FLT1-down|HBEGF-down IGF1-up|HBEGF-down IL1R2-down|HBEGF-down PLAU-up|HBEGF-down PROM1-up|HBEGF-down ZBTB16-down|HSPA1A-down IGF1-up|HSPA1B-down ZBTB16-down|JUN-down IGF1-up|MMP2-up IGF1-up|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|MMP2-up PLAU-up|MMP2-up PROM1-up	HBEGF-down_1839 CCND2-up_894|JUN-down_3725 CCND2-up_894|MMP2-up_4313 CCND2-up_894|HBEGF-down_1839 FLT1-down_2321|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|MMP2-up_4313 FLT1-down_2321|HBEGF-down_1839 IGF1-up_3479|HBEGF-down_1839 IL1R2-down_7850|HBEGF-down_1839 PLAU-up_5328|HBEGF-down_1839 PROM1-up_8842|HBEGF-down_1839 ZBTB16-down_7704|HSPA1A-down_3303 IGF1-up_3479|HSPA1B-down_3304 ZBTB16-down_7704|JUN-down_3725 IGF1-up_3479|MMP2-up_4313 IGF1-up_3479|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 PROM1-up_8842
hsa04915	hsa05206	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	HBEGF-down CCND1-up|HSPA1A-down CCND1-up|JUN-down CCND1-up|MMP2-up CCND1-up|HBEGF-down CCND2-up|JUN-down CCND2-up|MMP2-up CCND2-up|JUN-down CYP24A1-up|HBEGF-down HMOX1-down|HBEGF-down MCL1-down|HBEGF-down MMP16-up|HBEGF-down PDGFRA-down|HBEGF-down PLAU-up|HBEGF-down THBS1-down|HBEGF-down TNC-up|HSPA1A-down HMOX1-down|HSPA1B-down HMOX1-down|JUN-down HMOX1-down|MMP2-up HMOX1-down|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|JUN-down IRS2-down|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|MMP2-up MCL1-down|MMP2-up MMP16-up|MMP2-up PDGFRA-down|MMP2-up PLAU-up|MMP2-up SERPINB5-up|MMP2-up SOX4-up|MMP2-up THBS1-down|MMP2-up TNC-up	HBEGF-down_1839 CCND1-up_595|HSPA1A-down_3303 CCND1-up_595|JUN-down_3725 CCND1-up_595|MMP2-up_4313 CCND1-up_595|HBEGF-down_1839 CCND2-up_894|JUN-down_3725 CCND2-up_894|MMP2-up_4313 CCND2-up_894|JUN-down_3725 CYP24A1-up_1591|HBEGF-down_1839 HMOX1-down_3162|HBEGF-down_1839 MCL1-down_4170|HBEGF-down_1839 MMP16-up_4325|HBEGF-down_1839 PDGFRA-down_5156|HBEGF-down_1839 PLAU-up_5328|HBEGF-down_1839 THBS1-down_7057|HBEGF-down_1839 TNC-up_3371|HSPA1A-down_3303 HMOX1-down_3162|HSPA1B-down_3304 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|MMP2-up_4313 HMOX1-down_3162|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|JUN-down_3725 IRS2-down_8660|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|MMP2-up_4313 MCL1-down_4170|MMP2-up_4313 MMP16-up_4325|MMP2-up_4313 PDGFRA-down_5156|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 SERPINB5-up_5268|MMP2-up_4313 SOX4-up_6659|MMP2-up_4313 THBS1-down_7057|MMP2-up_4313 TNC-up_3371
hsa04915	hsa05323	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.009	MMP2-up CTSK-up|GABBR2-up CXCL12-up|HBEGF-down CXCL12-up|MMP2-up CXCL12-up|HBEGF-down FLT1-down|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|MMP2-up FLT1-down|HBEGF-down JUN-down|HBEGF-down MMP1-up|HBEGF-down TGFB3-up|HSPA1A-down JUN-down|HSPA1B-down JUN-down|MMP2-up MMP1-up|MMP2-up TGFB3-up	MMP2-up_4313 CTSK-up_1513|GABBR2-up_9568 CXCL12-up_6387|HBEGF-down_1839 CXCL12-up_6387|MMP2-up_4313 CXCL12-up_6387|HBEGF-down_1839 FLT1-down_2321|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|MMP2-up_4313 FLT1-down_2321|HBEGF-down_1839 JUN-down_3725|HBEGF-down_1839 MMP1-up_4312|HBEGF-down_1839 TGFB3-up_7043|HSPA1A-down_3303 JUN-down_3725|HSPA1B-down_3304 JUN-down_3725|MMP2-up_4313 MMP1-up_4312|MMP2-up_4313 TGFB3-up_7043
hsa04915	hsa05414	Estrogen signaling pathway - Homo sapiens (human)	HBEGF,HSPA1A,HSPA1B,JUN,GABBR1,GABBR2,KCNJ5,MMP2	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.047	HBEGF-down IGF1-up|HBEGF-down TGFB3-up|HSPA1A-down IGF1-up|HSPA1A-down TNNC1-down|HSPA1B-down TNNC1-down|JUN-down IGF1-up|MMP2-up IGF1-up|JUN-down ITGB4-up|MMP2-up ITGB4-up|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down|KCNJ5-up PLN-up|MMP2-up PLN-up|MMP2-up TGFB3-up|MMP2-up TTN-down	HBEGF-down_1839 IGF1-up_3479|HBEGF-down_1839 TGFB3-up_7043|HSPA1A-down_3303 IGF1-up_3479|HSPA1A-down_3303 TNNC1-down_7134|HSPA1B-down_3304 TNNC1-down_7134|JUN-down_3725 IGF1-up_3479|MMP2-up_4313 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|KCNJ5-up_3762 PLN-up_5350|MMP2-up_4313 PLN-up_5350|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273
hsa04921	hsa04970	Oxytocin signaling pathway - Homo sapiens (human)	JUN,NPR1,CCND1,GUCY1A3,KCNJ5,PRKAA2	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	0.005	NPR1-down ADRB1-down|JUN-down AQP5-up|CCND1-up KCNMA1-up|CCND1-up MUC5B-up|GUCY1A3-up JUN-down|JUN-down KCNMA1-up|JUN-down KCNN4-up|JUN-down MUC5B-up|KCNJ5-up KCNMA1-up|KCNJ5-up KCNN4-up|NPR1-down KCNMA1-up	NPR1-down_4881 ADRB1-down_153|JUN-down_3725 AQP5-up_362|CCND1-up_595 KCNMA1-up_3778|CCND1-up_595 MUC5B-up_727897|GUCY1A3-up_2982 JUN-down_3725|JUN-down_3725 KCNMA1-up_3778|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MUC5B-up_727897|KCNJ5-up_3762 KCNMA1-up_3778|KCNJ5-up_3762 KCNN4-up_3783|NPR1-down_4881 KCNMA1-up_3778
hsa04921	hsa05032	Oxytocin signaling pathway - Homo sapiens (human)	JUN,NPR1,CCND1,GUCY1A3,KCNJ5,PRKAA2	Morphine addiction - Homo sapiens (human)	ARRB1,PDE4B,PDE4D,GABBR1,GABBR2,KCNJ5,PDE7B	0.028	CCND1-up ARRB1-down|JUN-down ARRB1-down|GUCY1A3-up PDE4B-down|GUCY1A3-up PDE4D-down|GUCY1A3-up PDE7B-up|JUN-down KCNJ5-up|JUN-down PDE4B-down|JUN-down PDE4D-down|NPR1-down PDE4B-down|NPR1-down PDE4D-down|NPR1-down PDE7B-up|PRKAA2-up PDE4B-down|PRKAA2-up PDE4D-down|PRKAA2-up PDE7B-up	CCND1-up_595 ARRB1-down_408|JUN-down_3725 ARRB1-down_408|GUCY1A3-up_2982 PDE4B-down_5142|GUCY1A3-up_2982 PDE4D-down_5144|GUCY1A3-up_2982 PDE7B-up_27115|JUN-down_3725 KCNJ5-up_3762|JUN-down_3725 PDE4B-down_5142|JUN-down_3725 PDE4D-down_5144|NPR1-down_4881 PDE4B-down_5142|NPR1-down_4881 PDE4D-down_5144|NPR1-down_4881 PDE7B-up_27115|PRKAA2-up_5563 PDE4B-down_5142|PRKAA2-up_5563 PDE4D-down_5144|PRKAA2-up_5563 PDE7B-up_27115
hsa04921	hsa05202	Oxytocin signaling pathway - Homo sapiens (human)	JUN,NPR1,CCND1,GUCY1A3,KCNJ5,PRKAA2	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.029	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|JUN-down CCND2-up|PRKAA2-up CCND2-up|JUN-down FLT1-down|GUCY1A3-up NFKBIZ-down|JUN-down IGF1-up|PRKAA2-up IGF1-up|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|NPR1-down NFKBIZ-down|NPR1-down ZBTB16-down	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|JUN-down_3725 CCND2-up_894|PRKAA2-up_5563 CCND2-up_894|JUN-down_3725 FLT1-down_2321|GUCY1A3-up_2982 NFKBIZ-down_64332|JUN-down_3725 IGF1-up_3479|PRKAA2-up_5563 IGF1-up_3479|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|NPR1-down_4881 NFKBIZ-down_64332|NPR1-down_4881 ZBTB16-down_7704
hsa04933	hsa04974	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0	CCND1-up COL18A1-up|CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up MME-down|TGFB3-up COL10A1-up|JUN-down COL14A1-up|MMP2-up COL14A1-up|TGFB3-up COL14A1-up|F3-down COL15A1-up|MMP2-up COL15A1-up|MMP2-up COL17A1-up|F3-down COL18A1-up|FIGF-down COL18A1-up|JUN-down COL18A1-up|MMP2-up COL18A1-up|SERPINE1-down COL18A1-up|TGFB3-up COL18A1-up|VCAM1-up COL18A1-up|COL1A1-up FIGF-down|COL1A1-up JUN-down|COL1A1-up SERPINE1-down|COL1A2-up FIGF-down|COL1A2-up JUN-down|COL1A2-up SERPINE1-down|COL3A1-up JUN-down|COL3A1-up SERPINE1-down|JUN-down COL5A1-up|MMP2-up COL5A1-up|SERPINE1-down COL5A1-up|TGFB3-up COL5A1-up|JUN-down COL5A2-up|MMP2-up COL5A2-up|SERPINE1-down COL5A2-up|TGFB3-up COL5A2-up|JUN-down COL6A1-up|MMP2-up COL6A1-up|TGFB3-up COL6A1-up|JUN-down COL6A3-up|MMP2-up COL6A3-up|TGFB3-up COL6A3-up|JUN-down COL7A1-up|MMP2-up COL7A1-up|SERPINE1-down COL7A1-up|JUN-down KCNN4-up|JUN-down MME-down|JUN-down PRSS1-up|MMP2-up MME-down|SERPINE1-down MME-down|VCAM1-up MME-down|SERPINE1-down PRSS1-up	CCND1-up_595 COL18A1-up_80781|CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 MME-down_4311|TGFB3-up_7043 COL10A1-up_1300|JUN-down_3725 COL14A1-up_7373|MMP2-up_4313 COL14A1-up_7373|TGFB3-up_7043 COL14A1-up_7373|F3-down_2152 COL15A1-up_1306|MMP2-up_4313 COL15A1-up_1306|MMP2-up_4313 COL17A1-up_1308|F3-down_2152 COL18A1-up_80781|FIGF-down_2277 COL18A1-up_80781|JUN-down_3725 COL18A1-up_80781|MMP2-up_4313 COL18A1-up_80781|SERPINE1-down_5054 COL18A1-up_80781|TGFB3-up_7043 COL18A1-up_80781|VCAM1-up_7412 COL18A1-up_80781|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SERPINE1-down_5054|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 SERPINE1-down_5054|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 SERPINE1-down_5054|JUN-down_3725 COL5A1-up_1289|MMP2-up_4313 COL5A1-up_1289|SERPINE1-down_5054 COL5A1-up_1289|TGFB3-up_7043 COL5A1-up_1289|JUN-down_3725 COL5A2-up_1290|MMP2-up_4313 COL5A2-up_1290|SERPINE1-down_5054 COL5A2-up_1290|TGFB3-up_7043 COL5A2-up_1290|JUN-down_3725 COL6A1-up_1291|MMP2-up_4313 COL6A1-up_1291|TGFB3-up_7043 COL6A1-up_1291|JUN-down_3725 COL6A3-up_1293|MMP2-up_4313 COL6A3-up_1293|TGFB3-up_7043 COL6A3-up_1293|JUN-down_3725 COL7A1-up_1294|MMP2-up_4313 COL7A1-up_1294|SERPINE1-down_5054 COL7A1-up_1294|JUN-down_3725 KCNN4-up_3783|JUN-down_3725 MME-down_4311|JUN-down_3725 PRSS1-up_5644|MMP2-up_4313 MME-down_4311|SERPINE1-down_5054 MME-down_4311|VCAM1-up_7412 MME-down_4311|SERPINE1-down_5054 PRSS1-up_5644
hsa04933	hsa04978	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	0	CCND1-up HMOX1-down|CCND1-up TF-up|COL1A1-up HMOX1-down|COL1A1-up TF-up|COL1A2-up HMOX1-down|COL1A2-up TF-up|COL3A1-up TF-up|F3-down HMOX1-down|F3-down TF-up|FIGF-down HMOX1-down|JUN-down HMOX1-down|MMP2-up HMOX1-down|SERPINE1-down HMOX1-down|VCAM1-up HMOX1-down|JUN-down MT1E-down|JUN-down MT1X-down|JUN-down MT2A-down|JUN-down TF-up|MMP2-up MT1E-down|MMP2-up TF-up|VCAM1-up MT2A-down|SERPINE1-down TF-up|TGFB3-up TF-up|VCAM1-up TF-up	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 TF-up_7018|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 TF-up_7018|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 TF-up_7018|COL3A1-up_1281 TF-up_7018|F3-down_2152 HMOX1-down_3162|F3-down_2152 TF-up_7018|FIGF-down_2277 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|MMP2-up_4313 HMOX1-down_3162|SERPINE1-down_5054 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|JUN-down_3725 MT1E-down_4493|JUN-down_3725 MT1X-down_4501|JUN-down_3725 MT2A-down_4502|JUN-down_3725 TF-up_7018|MMP2-up_4313 MT1E-down_4493|MMP2-up_4313 TF-up_7018|VCAM1-up_7412 MT2A-down_4502|SERPINE1-down_5054 TF-up_7018|TGFB3-up_7043 TF-up_7018|VCAM1-up_7412 TF-up_7018
hsa04933	hsa05145	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up LAMA3-down|CCND1-up LDLR-down|CCND1-up TGFB3-up|COL1A1-up HSPA1A-down|COL1A1-up LAMA3-down|COL1A1-up LDLR-down|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up LAMA3-down|COL1A2-up TGFB3-up|COL3A1-up HSPA1A-down|COL3A1-up LAMA3-down|COL3A1-up TGFB3-up|F3-down HSPA1A-down|FIGF-down TGFB3-up|JUN-down HSPA1A-down|JUN-down HSPA1B-down|JUN-down JAK1-down|MMP2-up JAK1-down|SERPINE1-down JAK1-down|VCAM1-up JAK1-down|JUN-down LAMA3-down|JUN-down LDLR-down|JUN-down TGFB3-up|MMP2-up LAMA3-down|SERPINE1-down LAMA3-down|VCAM1-up LAMA3-down|MMP2-up LDLR-down|SERPINE1-down LDLR-down|VCAM1-up LDLR-down|MMP2-up TGFB3-up|SERPINE1-down TGFB3-up	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 LDLR-down_3949|CCND1-up_595 TGFB3-up_7043|COL1A1-up_1277 HSPA1A-down_3303|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 HSPA1A-down_3303|COL3A1-up_1281 LAMA3-down_3909|COL3A1-up_1281 TGFB3-up_7043|F3-down_2152 HSPA1A-down_3303|FIGF-down_2277 TGFB3-up_7043|JUN-down_3725 HSPA1A-down_3303|JUN-down_3725 HSPA1B-down_3304|JUN-down_3725 JAK1-down_3716|MMP2-up_4313 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 LDLR-down_3949|JUN-down_3725 TGFB3-up_7043|MMP2-up_4313 LAMA3-down_3909|SERPINE1-down_5054 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|MMP2-up_4313 LDLR-down_3949|SERPINE1-down_5054 LDLR-down_3949|VCAM1-up_7412 LDLR-down_3949|MMP2-up_4313 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04933	hsa05146	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.001	CCND1-up COL1A1-up|CCND1-up COL1A2-up|CCND1-up LAMA3-down|CCND1-up TGFB3-up|COL1A1-up FIGF-down|COL1A1-up JUN-down|COL1A1-up SERPINE1-down|COL1A2-up FIGF-down|COL1A2-up JUN-down|COL1A2-up SERPINE1-down|COL3A1-up JUN-down|COL3A1-up SERPINE1-down|F3-down IL1R2-down|FIGF-down TGFB3-up|JUN-down LAMA3-down|JUN-down SERPINB3-up|JUN-down TGFB3-up|MMP2-up LAMA3-down|SERPINE1-down LAMA3-down|VCAM1-up LAMA3-down|MMP2-up SERPINB3-up|MMP2-up TGFB3-up|SERPINE1-down SERPINB3-up|SERPINE1-down TGFB3-up	CCND1-up_595 COL1A1-up_1277|CCND1-up_595 COL1A2-up_1278|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 TGFB3-up_7043|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SERPINE1-down_5054|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 SERPINE1-down_5054|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 SERPINE1-down_5054|F3-down_2152 IL1R2-down_7850|FIGF-down_2277 TGFB3-up_7043|JUN-down_3725 LAMA3-down_3909|JUN-down_3725 SERPINB3-up_6317|JUN-down_3725 TGFB3-up_7043|MMP2-up_4313 LAMA3-down_3909|SERPINE1-down_5054 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|MMP2-up_4313 SERPINB3-up_6317|MMP2-up_4313 TGFB3-up_7043|SERPINE1-down_5054 SERPINB3-up_6317|SERPINE1-down_5054 TGFB3-up_7043
hsa04933	hsa05152	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0.001	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up TGFB3-up|COL1A1-up CD74-up|COL1A2-up CD74-up|COL3A1-up CD74-up|FIGF-down CD74-up|JUN-down CD74-up|MMP2-up CD74-up|VCAM1-up CD74-up|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up TGFB3-up|COL3A1-up TGFB3-up|FIGF-down TGFB3-up|JUN-down JAK1-down|MMP2-up JAK1-down|SERPINE1-down JAK1-down|VCAM1-up JAK1-down|JUN-down TGFB3-up|MMP2-up TGFB3-up|SERPINE1-down TGFB3-up	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 TGFB3-up_7043|COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|COL3A1-up_1281 CD74-up_972|FIGF-down_2277 CD74-up_972|JUN-down_3725 CD74-up_972|MMP2-up_4313 CD74-up_972|VCAM1-up_7412 CD74-up_972|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 TGFB3-up_7043|FIGF-down_2277 TGFB3-up_7043|JUN-down_3725 JAK1-down_3716|MMP2-up_4313 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|JUN-down_3725 TGFB3-up_7043|MMP2-up_4313 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04933	hsa05160	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0	CCND1-up JAK1-down|CCND1-up LDLR-down|CCND1-up SOCS3-down|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|COL3A1-up CLDN1-up|MMP2-up CLDN1-up|FIGF-down CLDN5-down|JUN-down CLDN5-down|MMP2-up CLDN5-down|SERPINE1-down CLDN5-down|VCAM1-up CLDN5-down|COL1A1-up LDLR-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|F3-down SOCS3-down|JUN-down JAK1-down|MMP2-up JAK1-down|SERPINE1-down JAK1-down|VCAM1-up JAK1-down|JUN-down LDLR-down|JUN-down SOCS3-down|MMP2-up LDLR-down|SERPINE1-down LDLR-down|VCAM1-up LDLR-down|MMP2-up SOCS3-down|SERPINE1-down SOCS3-down|VCAM1-up SOCS3-down	CCND1-up_595 JAK1-down_3716|CCND1-up_595 LDLR-down_3949|CCND1-up_595 SOCS3-down_9021|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|COL3A1-up_1281 CLDN1-up_9076|MMP2-up_4313 CLDN1-up_9076|FIGF-down_2277 CLDN5-down_7122|JUN-down_3725 CLDN5-down_7122|MMP2-up_4313 CLDN5-down_7122|SERPINE1-down_5054 CLDN5-down_7122|VCAM1-up_7412 CLDN5-down_7122|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|F3-down_2152 SOCS3-down_9021|JUN-down_3725 JAK1-down_3716|MMP2-up_4313 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|JUN-down_3725 LDLR-down_3949|JUN-down_3725 SOCS3-down_9021|MMP2-up_4313 LDLR-down_3949|SERPINE1-down_5054 LDLR-down_3949|VCAM1-up_7412 LDLR-down_3949|MMP2-up_4313 SOCS3-down_9021|SERPINE1-down_5054 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04933	hsa05164	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	0.008	CCND1-up HSPA1A-down|CCND1-up JAK1-down|CCND1-up SOCS3-down|COL1A1-up HSPA1A-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|COL3A1-up HSPA1A-down|F3-down HSPA1A-down|F3-down JUN-down|F3-down SOCS3-down|FIGF-down JUN-down|MMP2-up JAK1-down|SERPINE1-down JAK1-down|VCAM1-up JAK1-down|MMP2-up SOCS3-down|MMP2-up TMPRSS4-up|SERPINE1-down PRSS1-up|SERPINE1-down SOCS3-down|SERPINE1-down TMPRSS4-up|VCAM1-up SOCS3-down	CCND1-up_595 HSPA1A-down_3303|CCND1-up_595 JAK1-down_3716|CCND1-up_595 SOCS3-down_9021|COL1A1-up_1277 HSPA1A-down_3303|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|COL3A1-up_1281 HSPA1A-down_3303|F3-down_2152 HSPA1A-down_3303|F3-down_2152 JUN-down_3725|F3-down_2152 SOCS3-down_9021|FIGF-down_2277 JUN-down_3725|MMP2-up_4313 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|MMP2-up_4313 SOCS3-down_9021|MMP2-up_4313 TMPRSS4-up_56649|SERPINE1-down_5054 PRSS1-up_5644|SERPINE1-down_5054 SOCS3-down_9021|SERPINE1-down_5054 TMPRSS4-up_56649|VCAM1-up_7412 SOCS3-down_9021
hsa04933	hsa05166	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.001	CCND1-up FIGF-down|CCND1-up SERPINE1-down|COL1A2-up CCND2-up|COL3A1-up CCND2-up|MMP2-up CCND2-up|SERPINE1-down CCND2-up|COL1A1-up MYB-up|COL1A1-up PDGFRA-down|COL1A1-up TGFB3-up|COL1A1-up VCAM1-up|COL1A2-up JAK1-down|COL1A2-up MYB-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL3A1-up PDGFRA-down|COL3A1-up TGFB3-up|F3-down IL1R2-down|F3-down JUN-down|F3-down PDGFRA-down|F3-down VCAM1-up|FIGF-down JUN-down|FIGF-down PDGFRA-down|FIGF-down TGFB3-up|FIGF-down VCAM1-up|MMP2-up JAK1-down|SERPINE1-down JAK1-down|MMP2-up MYB-up|MMP2-up PDGFRA-down|MMP2-up TGFB3-up|MMP2-up VCAM1-up|SERPINE1-down MYB-up|SERPINE1-down TGFB3-up|SERPINE1-down VCAM1-up	CCND1-up_595 FIGF-down_2277|CCND1-up_595 SERPINE1-down_5054|COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|MMP2-up_4313 CCND2-up_894|SERPINE1-down_5054 CCND2-up_894|COL1A1-up_1277 MYB-up_4602|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 MYB-up_4602|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 TGFB3-up_7043|F3-down_2152 IL1R2-down_7850|F3-down_2152 JUN-down_3725|F3-down_2152 PDGFRA-down_5156|F3-down_2152 VCAM1-up_7412|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 TGFB3-up_7043|FIGF-down_2277 VCAM1-up_7412|MMP2-up_4313 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|MMP2-up_4313 MYB-up_4602|MMP2-up_4313 PDGFRA-down_5156|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 VCAM1-up_7412|SERPINE1-down_5054 MYB-up_4602|SERPINE1-down_5054 TGFB3-up_7043|SERPINE1-down_5054 VCAM1-up_7412
hsa04933	hsa05168	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	CCND1-up CD74-up|CCND1-up JAK1-down|CCND1-up SOCS3-down|COL1A1-up CD74-up|COL1A2-up CD74-up|COL3A1-up CD74-up|FIGF-down CD74-up|MMP2-up CD74-up|VCAM1-up CD74-up|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|F3-down JUN-down|F3-down SOCS3-down|FIGF-down JUN-down|MMP2-up JAK1-down|SERPINE1-down JAK1-down|VCAM1-up JAK1-down|MMP2-up SOCS3-down|SERPINE1-down SOCS3-down|VCAM1-up SOCS3-down	CCND1-up_595 CD74-up_972|CCND1-up_595 JAK1-down_3716|CCND1-up_595 SOCS3-down_9021|COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|COL3A1-up_1281 CD74-up_972|FIGF-down_2277 CD74-up_972|MMP2-up_4313 CD74-up_972|VCAM1-up_7412 CD74-up_972|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|F3-down_2152 JUN-down_3725|F3-down_2152 SOCS3-down_9021|FIGF-down_2277 JUN-down_3725|MMP2-up_4313 JAK1-down_3716|SERPINE1-down_5054 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|MMP2-up_4313 SOCS3-down_9021|SERPINE1-down_5054 SOCS3-down_9021|VCAM1-up_7412 SOCS3-down_9021
hsa04933	hsa05200	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.004	CCND1-up SERPINE1-down|COL1A1-up CXCL12-up|COL1A1-up IGF1-up|COL1A1-up LAMA3-down|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up PDGFRA-down|COL1A1-up TCF7L2-up|COL1A1-up TGFB3-up|COL1A1-up ZBTB16-down|COL1A2-up CXCL12-up|COL1A2-up EDNRB-down|COL1A2-up IGF1-up|COL1A2-up JAK1-down|COL1A2-up LAMA3-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL3A1-up CXCL12-up|COL3A1-up IGF1-up|COL3A1-up LAMA3-down|COL3A1-up MMP1-up|COL3A1-up MMP2-up|COL3A1-up PDGFRA-down|COL3A1-up TGFB3-up|F3-down CXCL12-up|SERPINE1-down CXCL12-up|VCAM1-up CXCL12-up|SERPINE1-down EDNRB-down|VCAM1-up EDNRB-down|F3-down IGF1-up|F3-down JUN-down|F3-down MMP2-up|F3-down PDGFRA-down|SERPINE1-down IGF1-up|VCAM1-up IGF1-up|SERPINE1-down JAK1-down|VCAM1-up JAK1-down|SERPINE1-down LAMA3-down|VCAM1-up LAMA3-down|SERPINE1-down MMP1-up|VCAM1-up MMP1-up|MMP2-up SERPINE1-down|VCAM1-up PDGFRA-down|SERPINE1-down TGFB3-up	CCND1-up_595 SERPINE1-down_5054|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TCF7L2-up_6934|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 EDNRB-down_1910|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 CXCL12-up_6387|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 LAMA3-down_3909|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 TGFB3-up_7043|F3-down_2152 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|VCAM1-up_7412 CXCL12-up_6387|SERPINE1-down_5054 EDNRB-down_1910|VCAM1-up_7412 EDNRB-down_1910|F3-down_2152 IGF1-up_3479|F3-down_2152 JUN-down_3725|F3-down_2152 MMP2-up_4313|F3-down_2152 PDGFRA-down_5156|SERPINE1-down_5054 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|SERPINE1-down_5054 JAK1-down_3716|VCAM1-up_7412 JAK1-down_3716|SERPINE1-down_5054 LAMA3-down_3909|VCAM1-up_7412 LAMA3-down_3909|SERPINE1-down_5054 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|MMP2-up_4313 SERPINE1-down_5054|VCAM1-up_7412 PDGFRA-down_5156|SERPINE1-down_5054 TGFB3-up_7043
hsa04933	hsa05202	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|COL1A2-up CCND2-up|COL3A1-up CCND2-up|JUN-down CCND2-up|MMP2-up CCND2-up|SERPINE1-down CCND2-up|TGFB3-up CCND2-up|COL1A1-up FLT1-down|COL1A1-up IGF1-up|COL1A1-up PLAU-up|COL1A1-up PROM1-up|COL1A1-up SIX1-up|COL1A1-up ZBTB16-down|COL1A2-up FLT1-down|COL1A2-up IGF1-up|COL1A2-up PLAU-up|COL3A1-up FLT1-down|COL3A1-up IGF1-up|COL3A1-up PLAU-up|F3-down FLT1-down|F3-down IGF1-up|F3-down IL1R2-down|F3-down PLAU-up|FIGF-down FLT1-down|FIGF-down IGF1-up|FIGF-down PLAU-up|FIGF-down PROM1-up|JUN-down FLT1-down|MMP2-up FLT1-down|SERPINE1-down FLT1-down|TGFB3-up FLT1-down|VCAM1-up FLT1-down|JUN-down IGF1-up|MMP2-up IGF1-up|SERPINE1-down IGF1-up|TGFB3-up IGF1-up|VCAM1-up IGF1-up|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|MMP2-up PLAU-up|MMP2-up PROM1-up|SERPINE1-down PLAU-up|TGFB3-up PLAU-up|VCAM1-up PLAU-up|SERPINE1-down PROM1-up|VCAM1-up PROM1-up|TGFB3-up SIX1-up	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|JUN-down_3725 CCND2-up_894|MMP2-up_4313 CCND2-up_894|SERPINE1-down_5054 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 PROM1-up_8842|COL1A1-up_1277 SIX1-up_6495|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 PLAU-up_5328|COL3A1-up_1281 FLT1-down_2321|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 PLAU-up_5328|F3-down_2152 FLT1-down_2321|F3-down_2152 IGF1-up_3479|F3-down_2152 IL1R2-down_7850|F3-down_2152 PLAU-up_5328|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 PROM1-up_8842|JUN-down_3725 FLT1-down_2321|MMP2-up_4313 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|JUN-down_3725 IGF1-up_3479|MMP2-up_4313 IGF1-up_3479|SERPINE1-down_5054 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 PROM1-up_8842|SERPINE1-down_5054 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|SERPINE1-down_5054 PROM1-up_8842|VCAM1-up_7412 PROM1-up_8842|TGFB3-up_7043 SIX1-up_6495
hsa04933	hsa05205	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	F3-down CAV2-down|JUN-down CAV2-down|SERPINE1-down CAV2-down|CCND1-up FIGF-down|CCND1-up JUN-down|CCND1-up SERPINE1-down|COL1A1-up IGF1-up|COL1A1-up MMP2-up|COL1A1-up PLAU-up|COL1A1-up THBS1-down|COL1A2-up IGF1-up|COL1A2-up MMP2-up|COL1A2-up PLAU-up|COL1A2-up THBS1-down|COL3A1-up IGF1-up|COL3A1-up MMP2-up|COL3A1-up PLAU-up|COL3A1-up THBS1-down|F3-down FLNC-up|F3-down HBEGF-down|F3-down IGF1-up|F3-down MMP2-up|F3-down PLAU-up|F3-down THBS1-down|FIGF-down HBEGF-down|FIGF-down IGF1-up|FIGF-down MMP2-up|FIGF-down PLAU-up|FIGF-down THBS1-down|JUN-down FLNC-up|VCAM1-up FLNC-up|JUN-down FZD5-down|JUN-down HBEGF-down|SERPINE1-down HBEGF-down|TGFB3-up HBEGF-down|VCAM1-up HBEGF-down|JUN-down IGF1-up|SERPINE1-down IGF1-up|TGFB3-up IGF1-up|VCAM1-up IGF1-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|MMP2-up SERPINE1-down|SERPINE1-down PLAU-up|TGFB3-up PLAU-up|VCAM1-up PLAU-up|SERPINE1-down THBS1-down|TGFB3-up THBS1-down|VCAM1-up THBS1-down	F3-down_2152 CAV2-down_858|JUN-down_3725 CAV2-down_858|SERPINE1-down_5054 CAV2-down_858|CCND1-up_595 FIGF-down_2277|CCND1-up_595 JUN-down_3725|CCND1-up_595 SERPINE1-down_5054|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 THBS1-down_7057|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 PLAU-up_5328|COL3A1-up_1281 THBS1-down_7057|F3-down_2152 FLNC-up_2318|F3-down_2152 HBEGF-down_1839|F3-down_2152 IGF1-up_3479|F3-down_2152 MMP2-up_4313|F3-down_2152 PLAU-up_5328|F3-down_2152 THBS1-down_7057|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|JUN-down_3725 FLNC-up_2318|VCAM1-up_7412 FLNC-up_2318|JUN-down_3725 FZD5-down_7855|JUN-down_3725 HBEGF-down_1839|SERPINE1-down_5054 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|JUN-down_3725 IGF1-up_3479|SERPINE1-down_5054 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|MMP2-up_4313 SERPINE1-down_5054|SERPINE1-down_5054 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|SERPINE1-down_5054 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04933	hsa05206	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CCND1-up FIGF-down|CCND1-up JUN-down|CCND1-up SERPINE1-down|COL1A2-up CCND2-up|COL3A1-up CCND2-up|JUN-down CCND2-up|MMP2-up CCND2-up|SERPINE1-down CCND2-up|TGFB3-up CCND2-up|COL1A1-up CYP24A1-up|COL1A1-up HMOX1-down|COL1A1-up MMP16-up|COL1A1-up PDGFRA-down|COL1A1-up PLAU-up|COL1A1-up SOX4-up|COL1A1-up THBS1-down|COL1A1-up TNC-up|COL1A2-up HMOX1-down|COL1A2-up MMP16-up|COL1A2-up PDGFRA-down|COL1A2-up PLAU-up|COL1A2-up THBS1-down|COL1A2-up TNC-up|COL3A1-up MMP16-up|COL3A1-up PDGFRA-down|COL3A1-up PLAU-up|COL3A1-up THBS1-down|COL3A1-up TNC-up|JUN-down CYP24A1-up|F3-down HMOX1-down|F3-down PDGFRA-down|F3-down PLAU-up|F3-down THBS1-down|F3-down TNC-up|FIGF-down HMOX1-down|FIGF-down PDGFRA-down|FIGF-down PLAU-up|FIGF-down THBS1-down|FIGF-down TNC-up|JUN-down HMOX1-down|MMP2-up HMOX1-down|SERPINE1-down HMOX1-down|VCAM1-up HMOX1-down|JUN-down IRS2-down|SERPINE1-down IRS2-down|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|MMP2-up MCL1-down|SERPINE1-down MCL1-down|VCAM1-up MCL1-down|MMP2-up MMP16-up|SERPINE1-down MMP16-up|MMP2-up PDGFRA-down|MMP2-up PLAU-up|MMP2-up SERPINB5-up|MMP2-up SOX4-up|MMP2-up THBS1-down|MMP2-up TNC-up|TGFB3-up PDGFRA-down|VCAM1-up PDGFRA-down|SERPINE1-down PLAU-up|TGFB3-up PLAU-up|VCAM1-up PLAU-up|SERPINE1-down SERPINB5-up|SERPINE1-down THBS1-down|SERPINE1-down TNC-up|SERPINE1-down TP63-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up|VCAM1-up THBS1-down|VCAM1-up TNC-up	CCND1-up_595 FIGF-down_2277|CCND1-up_595 JUN-down_3725|CCND1-up_595 SERPINE1-down_5054|COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|JUN-down_3725 CCND2-up_894|MMP2-up_4313 CCND2-up_894|SERPINE1-down_5054 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|COL1A1-up_1277 CYP24A1-up_1591|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 MMP16-up_4325|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SOX4-up_6659|COL1A1-up_1277 THBS1-down_7057|COL1A1-up_1277 TNC-up_3371|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 MMP16-up_4325|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 THBS1-down_7057|COL1A2-up_1278 TNC-up_3371|COL3A1-up_1281 MMP16-up_4325|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 PLAU-up_5328|COL3A1-up_1281 THBS1-down_7057|COL3A1-up_1281 TNC-up_3371|JUN-down_3725 CYP24A1-up_1591|F3-down_2152 HMOX1-down_3162|F3-down_2152 PDGFRA-down_5156|F3-down_2152 PLAU-up_5328|F3-down_2152 THBS1-down_7057|F3-down_2152 TNC-up_3371|FIGF-down_2277 HMOX1-down_3162|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 TNC-up_3371|JUN-down_3725 HMOX1-down_3162|MMP2-up_4313 HMOX1-down_3162|SERPINE1-down_5054 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|JUN-down_3725 IRS2-down_8660|SERPINE1-down_5054 IRS2-down_8660|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|MMP2-up_4313 MCL1-down_4170|SERPINE1-down_5054 MCL1-down_4170|VCAM1-up_7412 MCL1-down_4170|MMP2-up_4313 MMP16-up_4325|SERPINE1-down_5054 MMP16-up_4325|MMP2-up_4313 PDGFRA-down_5156|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 SERPINB5-up_5268|MMP2-up_4313 SOX4-up_6659|MMP2-up_4313 THBS1-down_7057|MMP2-up_4313 TNC-up_3371|TGFB3-up_7043 PDGFRA-down_5156|VCAM1-up_7412 PDGFRA-down_5156|SERPINE1-down_5054 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|SERPINE1-down_5054 SERPINB5-up_5268|SERPINE1-down_5054 THBS1-down_7057|SERPINE1-down_5054 TNC-up_3371|SERPINE1-down_5054 TP63-up_8626|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 TNC-up_3371
hsa04933	hsa05219	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCND1-up FIGF-down|CCND1-up JUN-down|CCND1-up SERPINE1-down|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up THBS1-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up THBS1-down|COL3A1-up MMP1-up|COL3A1-up MMP2-up|COL3A1-up THBS1-down|F3-down HBEGF-down|F3-down MMP2-up|F3-down THBS1-down|FIGF-down HBEGF-down|FIGF-down MMP1-up|FIGF-down MMP2-up|FIGF-down THBS1-down|JUN-down HBEGF-down|SERPINE1-down HBEGF-down|TGFB3-up HBEGF-down|VCAM1-up HBEGF-down|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|SERPINE1-down MMP1-up|TGFB3-up MMP1-up|VCAM1-up MMP1-up|MMP2-up SERPINE1-down|SERPINE1-down THBS1-down|TGFB3-up THBS1-down|VCAM1-up THBS1-down	CCND1-up_595 FIGF-down_2277|CCND1-up_595 JUN-down_3725|CCND1-up_595 SERPINE1-down_5054|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 THBS1-down_7057|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 THBS1-down_7057|F3-down_2152 HBEGF-down_1839|F3-down_2152 MMP2-up_4313|F3-down_2152 THBS1-down_7057|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 THBS1-down_7057|JUN-down_3725 HBEGF-down_1839|SERPINE1-down_5054 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|SERPINE1-down_5054 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|MMP2-up_4313 SERPINE1-down_5054|SERPINE1-down_5054 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa04933	hsa05323	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|COL1A1-up CTSK-up|COL1A1-up CXCL12-up|COL1A1-up FLT1-down|COL1A1-up MMP1-up|COL1A1-up TGFB3-up|COL1A2-up CTSK-up|COL1A2-up CXCL12-up|COL1A2-up FLT1-down|COL1A2-up MMP1-up|COL1A2-up TGFB3-up|COL3A1-up CTSK-up|COL3A1-up CXCL12-up|COL3A1-up FLT1-down|COL3A1-up MMP1-up|COL3A1-up TGFB3-up|MMP2-up CTSK-up|SERPINE1-down CTSK-up|VCAM1-up CTSK-up|F3-down CXCL12-up|FIGF-down CXCL12-up|MMP2-up CXCL12-up|SERPINE1-down CXCL12-up|VCAM1-up CXCL12-up|F3-down FLT1-down|F3-down JUN-down|FIGF-down FLT1-down|FIGF-down JUN-down|FIGF-down MMP1-up|FIGF-down TGFB3-up|MMP2-up FLT1-down|SERPINE1-down FLT1-down|VCAM1-up FLT1-down|MMP2-up MMP1-up|SERPINE1-down MMP1-up|VCAM1-up MMP1-up|MMP2-up TGFB3-up|SERPINE1-down TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|COL1A1-up_1277 CTSK-up_1513|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 CTSK-up_1513|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 CTSK-up_1513|COL3A1-up_1281 CXCL12-up_6387|COL3A1-up_1281 FLT1-down_2321|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 TGFB3-up_7043|MMP2-up_4313 CTSK-up_1513|SERPINE1-down_5054 CTSK-up_1513|VCAM1-up_7412 CTSK-up_1513|F3-down_2152 CXCL12-up_6387|FIGF-down_2277 CXCL12-up_6387|MMP2-up_4313 CXCL12-up_6387|SERPINE1-down_5054 CXCL12-up_6387|VCAM1-up_7412 CXCL12-up_6387|F3-down_2152 FLT1-down_2321|F3-down_2152 JUN-down_3725|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 TGFB3-up_7043|MMP2-up_4313 FLT1-down_2321|SERPINE1-down_5054 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|MMP2-up_4313 MMP1-up_4312|SERPINE1-down_5054 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|MMP2-up_4313 TGFB3-up_7043|SERPINE1-down_5054 TGFB3-up_7043
hsa04933	hsa05410	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL3A1-up IGF1-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|COL3A1-up TGFB3-up|COL3A1-up TNNC1-down|COL3A1-up TTN-down|F3-down IGF1-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|JUN-down IGF1-up|MMP2-up IGF1-up|SERPINE1-down IGF1-up|VCAM1-up IGF1-up|JUN-down ITGB4-up|MMP2-up ITGB4-up|VCAM1-up ITGB4-up|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|MMP2-up TGFB3-up|MMP2-up TTN-down|SERPINE1-down TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|COL3A1-up_1281 TGFB3-up_7043|COL3A1-up_1281 TNNC1-down_7134|COL3A1-up_1281 TTN-down_7273|F3-down_2152 IGF1-up_3479|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|JUN-down_3725 IGF1-up_3479|MMP2-up_4313 IGF1-up_3479|SERPINE1-down_5054 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|SERPINE1-down_5054 TGFB3-up_7043
hsa04933	hsa05412	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|COL1A1-up CDH2-up|COL1A2-up CDH2-up|COL3A1-up CDH2-up|FIGF-down CDH2-up|JUN-down CDH2-up|MMP2-up CDH2-up|SERPINE1-down CDH2-up|TGFB3-up CDH2-up|VCAM1-up CDH2-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TCF7L2-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|TGFB3-up DES-up|JUN-down ITGB4-up|MMP2-up ITGB4-up|VCAM1-up ITGB4-up|TGFB3-up ITGB8-up|JUN-down TCF7L2-up|MMP2-up TCF7L2-up|TGFB3-up TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COL3A1-up_1281 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|MMP2-up_4313 CDH2-up_1000|SERPINE1-down_5054 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|VCAM1-up_7412 CDH2-up_1000|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TCF7L2-up_6934|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|TGFB3-up_7043 DES-up_1674|JUN-down_3725 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 TCF7L2-up_6934|MMP2-up_4313 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934
hsa04933	hsa05414	AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)	AGER,F3,FIGF,JUN,SERPINE1,CCND1,COL1A1,COL1A2,COL3A1,MMP2,TGFB3,VCAM1	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	SERPINE1-down ADRB1-down|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up PLN-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL3A1-up IGF1-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|COL3A1-up TGFB3-up|COL3A1-up TNNC1-down|COL3A1-up TTN-down|F3-down IGF1-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|JUN-down IGF1-up|MMP2-up IGF1-up|SERPINE1-down IGF1-up|VCAM1-up IGF1-up|JUN-down ITGB4-up|MMP2-up ITGB4-up|VCAM1-up ITGB4-up|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down|MMP2-up PLN-up|MMP2-up TGFB3-up|MMP2-up TTN-down|SERPINE1-down TGFB3-up	SERPINE1-down_5054 ADRB1-down_153|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 PLN-up_5350|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|COL3A1-up_1281 TGFB3-up_7043|COL3A1-up_1281 TNNC1-down_7134|COL3A1-up_1281 TTN-down_7273|F3-down_2152 IGF1-up_3479|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|JUN-down_3725 IGF1-up_3479|MMP2-up_4313 IGF1-up_3479|SERPINE1-down_5054 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MMP2-up_4313 PLN-up_5350|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|SERPINE1-down_5054 TGFB3-up_7043
hsa04970	hsa04972	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	Pancreatic secretion - Homo sapiens (human)	PLA2G1B,CLCA2,CPA3,KCNMA1,PRSS1	0.041	ADRB1-down KCNMA1-up|AQP5-up KCNMA1-up|KCNN4-up CLCA2-up	ADRB1-down_153 KCNMA1-up_3778|AQP5-up_362 KCNMA1-up_3778|KCNN4-up_3783 CLCA2-up_9635
hsa04970	hsa05168	Salivary secretion - Homo sapiens (human)	ADRB1,AQP5,GUCY1A3,KCNMA1,KCNN4,MUC5B	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.023	AQP5-up JUN-down|MUC5B-up CD74-up|GUCY1A3-up JUN-down|KCNMA1-up JAK1-down|KCNMA1-up JUN-down|KCNN4-up JUN-down|MUC5B-up JUN-down|MUC5B-up SOCS3-down	AQP5-up_362 JUN-down_3725|MUC5B-up_727897 CD74-up_972|GUCY1A3-up_2982 JUN-down_3725|KCNMA1-up_3778 JAK1-down_3716|KCNMA1-up_3778 JUN-down_3725|KCNN4-up_3783 JUN-down_3725|MUC5B-up_727897 JUN-down_3725|MUC5B-up_727897 SOCS3-down_9021
hsa04972	hsa04974	Pancreatic secretion - Homo sapiens (human)	PLA2G1B,CLCA2,CPA3,KCNMA1,PRSS1	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	0.004	CLCA2-up KCNN4-up|KCNMA1-up COL14A1-up|PLA2G1B-down COL1A2-up|PLA2G1B-down COL5A2-up|CPA3-up PLA2G1B-down|KCNMA1-up KCNN4-up|KCNMA1-up MME-down|PLA2G1B-down PRSS1-up	CLCA2-up_9635 KCNN4-up_3783|KCNMA1-up_3778 COL14A1-up_7373|PLA2G1B-down_5319 COL1A2-up_1278|PLA2G1B-down_5319 COL5A2-up_1290|CPA3-up_1359 PLA2G1B-down_5319|KCNMA1-up_3778 KCNN4-up_3783|KCNMA1-up_3778 MME-down_4311|PLA2G1B-down_5319 PRSS1-up_5644
hsa04972	hsa05414	Pancreatic secretion - Homo sapiens (human)	PLA2G1B,CLCA2,CPA3,KCNMA1,PRSS1	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.018	KCNMA1-up ADRB1-down|CLCA2-up ITGB4-up|PLA2G1B-down IGF1-up|PRSS1-up IGF1-up|KCNMA1-up PLN-up	KCNMA1-up_3778 ADRB1-down_153|CLCA2-up_9635 ITGB4-up_3691|PLA2G1B-down_5319 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|KCNMA1-up_3778 PLN-up_5350
hsa04974	hsa05145	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	0	COL10A1-up TGFB3-up|COL14A1-up LAMA3-down|COL14A1-up TGFB3-up|COL15A1-up LAMA3-down|COL17A1-up LAMA3-down|COL18A1-up LAMA3-down|COL18A1-up LDLR-down|COL18A1-up TGFB3-up|COL1A1-up HSPA1A-down|COL1A1-up LAMA3-down|COL1A1-up LDLR-down|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up LAMA3-down|COL1A2-up TGFB3-up|COL3A1-up HSPA1A-down|COL3A1-up LAMA3-down|COL3A1-up TGFB3-up|COL5A1-up LAMA3-down|COL5A1-up TGFB3-up|COL5A2-up LAMA3-down|COL5A2-up LDLR-down|COL5A2-up TGFB3-up|COL6A1-up LAMA3-down|COL6A1-up TGFB3-up|COL6A3-up LAMA3-down|COL6A3-up TGFB3-up|COL7A1-up LAMA3-down|MME-down HSPA1A-down|MME-down HSPA1B-down|MME-down LDLR-down	COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 LAMA3-down_3909|COL14A1-up_7373 TGFB3-up_7043|COL15A1-up_1306 LAMA3-down_3909|COL17A1-up_1308 LAMA3-down_3909|COL18A1-up_80781 LAMA3-down_3909|COL18A1-up_80781 LDLR-down_3949|COL18A1-up_80781 TGFB3-up_7043|COL1A1-up_1277 HSPA1A-down_3303|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 HSPA1A-down_3303|COL3A1-up_1281 LAMA3-down_3909|COL3A1-up_1281 TGFB3-up_7043|COL5A1-up_1289 LAMA3-down_3909|COL5A1-up_1289 TGFB3-up_7043|COL5A2-up_1290 LAMA3-down_3909|COL5A2-up_1290 LDLR-down_3949|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 LAMA3-down_3909|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 LAMA3-down_3909|COL6A3-up_1293 TGFB3-up_7043|COL7A1-up_1294 LAMA3-down_3909|MME-down_4311 HSPA1A-down_3303|MME-down_4311 HSPA1B-down_3304|MME-down_4311 LDLR-down_3949
hsa04974	hsa05146	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0	COL10A1-up COL1A1-up|COL10A1-up COL1A2-up|COL10A1-up COL3A1-up|COL10A1-up TGFB3-up|COL14A1-up COL1A1-up|COL14A1-up COL1A2-up|COL14A1-up COL3A1-up|COL14A1-up LAMA3-down|COL14A1-up TGFB3-up|COL15A1-up COL1A1-up|COL15A1-up COL1A2-up|COL15A1-up COL3A1-up|COL15A1-up LAMA3-down|COL17A1-up COL1A1-up|COL17A1-up COL1A2-up|COL17A1-up COL3A1-up|COL17A1-up LAMA3-down|COL18A1-up COL1A1-up|COL18A1-up COL1A2-up|COL18A1-up COL3A1-up|COL18A1-up LAMA3-down|COL18A1-up TGFB3-up|COL5A1-up LAMA3-down|COL5A1-up TGFB3-up|COL5A2-up LAMA3-down|COL5A2-up TGFB3-up|COL6A1-up LAMA3-down|COL6A1-up TGFB3-up|COL6A3-up LAMA3-down|COL6A3-up TGFB3-up|COL7A1-up LAMA3-down|PRSS1-up SERPINB3-up	COL10A1-up_1300 COL1A1-up_1277|COL10A1-up_1300 COL1A2-up_1278|COL10A1-up_1300 COL3A1-up_1281|COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 COL1A1-up_1277|COL14A1-up_7373 COL1A2-up_1278|COL14A1-up_7373 COL3A1-up_1281|COL14A1-up_7373 LAMA3-down_3909|COL14A1-up_7373 TGFB3-up_7043|COL15A1-up_1306 COL1A1-up_1277|COL15A1-up_1306 COL1A2-up_1278|COL15A1-up_1306 COL3A1-up_1281|COL15A1-up_1306 LAMA3-down_3909|COL17A1-up_1308 COL1A1-up_1277|COL17A1-up_1308 COL1A2-up_1278|COL17A1-up_1308 COL3A1-up_1281|COL17A1-up_1308 LAMA3-down_3909|COL18A1-up_80781 COL1A1-up_1277|COL18A1-up_80781 COL1A2-up_1278|COL18A1-up_80781 COL3A1-up_1281|COL18A1-up_80781 LAMA3-down_3909|COL18A1-up_80781 TGFB3-up_7043|COL5A1-up_1289 LAMA3-down_3909|COL5A1-up_1289 TGFB3-up_7043|COL5A2-up_1290 LAMA3-down_3909|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 LAMA3-down_3909|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 LAMA3-down_3909|COL6A3-up_1293 TGFB3-up_7043|COL7A1-up_1294 LAMA3-down_3909|PRSS1-up_5644 SERPINB3-up_6317
hsa04974	hsa05152	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0	COL1A1-up CD74-up|COL1A2-up CD74-up|COL3A1-up CD74-up|MME-down CD74-up|COL10A1-up TGFB3-up|COL14A1-up TGFB3-up|COL18A1-up TGFB3-up|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up TGFB3-up|COL3A1-up TGFB3-up|COL5A1-up TGFB3-up|COL5A2-up TGFB3-up|COL6A1-up TGFB3-up|COL6A3-up TGFB3-up	COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|COL3A1-up_1281 CD74-up_972|MME-down_4311 CD74-up_972|COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 TGFB3-up_7043|COL18A1-up_80781 TGFB3-up_7043|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 TGFB3-up_7043|COL5A1-up_1289 TGFB3-up_7043|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 TGFB3-up_7043
hsa04974	hsa05160	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0.032	COL17A1-up CLDN1-up|COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|COL3A1-up CLDN1-up|COL18A1-up LDLR-down|COL1A1-up LDLR-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|COL5A2-up LDLR-down|MME-down LDLR-down	COL17A1-up_1308 CLDN1-up_9076|COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|COL3A1-up_1281 CLDN1-up_9076|COL18A1-up_80781 LDLR-down_3949|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|COL5A2-up_1290 LDLR-down_3949|MME-down_4311 LDLR-down_3949
hsa04974	hsa05166	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0	COL18A1-up CCND1-up|COL1A1-up CCND1-up|COL1A2-up CCND1-up|MME-down CCND1-up|COL1A2-up CCND2-up|COL3A1-up CCND2-up|MME-down CCND2-up|COL10A1-up TGFB3-up|COL14A1-up JUN-down|COL14A1-up TGFB3-up|COL18A1-up JUN-down|COL18A1-up MYB-up|COL18A1-up TGFB3-up|COL18A1-up VCAM1-up|COL1A1-up JUN-down|COL1A1-up MYB-up|COL1A1-up PDGFRA-down|COL1A1-up TGFB3-up|COL1A1-up VCAM1-up|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL1A2-up MYB-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL3A1-up JUN-down|COL3A1-up PDGFRA-down|COL3A1-up TGFB3-up|COL5A1-up JUN-down|COL5A1-up PDGFRA-down|COL5A1-up TGFB3-up|COL5A2-up JUN-down|COL5A2-up TGFB3-up|COL6A1-up JUN-down|COL6A1-up MYB-up|COL6A1-up PDGFRA-down|COL6A1-up TGFB3-up|COL6A3-up JUN-down|COL6A3-up PDGFRA-down|COL6A3-up TGFB3-up|COL7A1-up JUN-down|KCNN4-up JUN-down|MME-down JUN-down|PRSS1-up JUN-down|MME-down MYB-up|MME-down PDGFRA-down|MME-down VCAM1-up	COL18A1-up_80781 CCND1-up_595|COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|MME-down_4311 CCND1-up_595|COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|MME-down_4311 CCND2-up_894|COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 JUN-down_3725|COL14A1-up_7373 TGFB3-up_7043|COL18A1-up_80781 JUN-down_3725|COL18A1-up_80781 MYB-up_4602|COL18A1-up_80781 TGFB3-up_7043|COL18A1-up_80781 VCAM1-up_7412|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MYB-up_4602|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MYB-up_4602|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 TGFB3-up_7043|COL5A1-up_1289 JUN-down_3725|COL5A1-up_1289 PDGFRA-down_5156|COL5A1-up_1289 TGFB3-up_7043|COL5A2-up_1290 JUN-down_3725|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MYB-up_4602|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 TGFB3-up_7043|COL7A1-up_1294 JUN-down_3725|KCNN4-up_3783 JUN-down_3725|MME-down_4311 JUN-down_3725|PRSS1-up_5644 JUN-down_3725|MME-down_4311 MYB-up_4602|MME-down_4311 PDGFRA-down_5156|MME-down_4311 VCAM1-up_7412
hsa04974	hsa05168	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0.007	COL1A1-up CD74-up|COL1A2-up CD74-up|COL3A1-up CD74-up|MME-down CD74-up|COL14A1-up JUN-down|COL18A1-up JUN-down|COL1A1-up JUN-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL3A1-up JUN-down|COL5A1-up JUN-down|COL5A2-up JUN-down|COL6A1-up JUN-down|COL6A3-up JUN-down|COL7A1-up JUN-down|KCNN4-up JUN-down|MME-down JUN-down|PRSS1-up JUN-down	COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|COL3A1-up_1281 CD74-up_972|MME-down_4311 CD74-up_972|COL14A1-up_7373 JUN-down_3725|COL18A1-up_80781 JUN-down_3725|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL3A1-up_1281 JUN-down_3725|COL5A1-up_1289 JUN-down_3725|COL5A2-up_1290 JUN-down_3725|COL6A1-up_1291 JUN-down_3725|COL6A3-up_1293 JUN-down_3725|COL7A1-up_1294 JUN-down_3725|KCNN4-up_3783 JUN-down_3725|MME-down_4311 JUN-down_3725|PRSS1-up_5644 JUN-down_3725
hsa04974	hsa05200	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0	COL18A1-up CCND1-up|COL1A1-up CCND1-up|COL1A2-up CCND1-up|MME-down CCND1-up|COL10A1-up MMP1-up|COL10A1-up TGFB3-up|COL14A1-up EDNRB-down|COL14A1-up FGF14-up|COL14A1-up JUN-down|COL14A1-up LAMA3-down|COL14A1-up MMP1-up|COL14A1-up MMP2-up|COL14A1-up TGFB3-up|COL15A1-up LAMA3-down|COL15A1-up MMP2-up|COL17A1-up LAMA3-down|COL17A1-up MMP1-up|COL17A1-up MMP2-up|COL18A1-up CXCL12-up|COL18A1-up EDNRB-down|COL18A1-up FIGF-down|COL18A1-up IGF1-up|COL18A1-up JUN-down|COL18A1-up LAMA3-down|COL18A1-up MMP1-up|COL18A1-up MMP2-up|COL18A1-up TGFB3-up|COL1A1-up CXCL12-up|COL1A1-up FIGF-down|COL1A1-up IGF1-up|COL1A1-up JUN-down|COL1A1-up LAMA3-down|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up PDGFRA-down|COL1A1-up TCF7L2-up|COL1A1-up TGFB3-up|COL1A1-up ZBTB16-down|COL1A2-up CXCL12-up|COL1A2-up EDNRB-down|COL1A2-up FIGF-down|COL1A2-up IGF1-up|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL1A2-up LAMA3-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL3A1-up CXCL12-up|COL3A1-up IGF1-up|COL3A1-up JUN-down|COL3A1-up LAMA3-down|COL3A1-up MMP1-up|COL3A1-up MMP2-up|COL3A1-up PDGFRA-down|COL3A1-up TGFB3-up|COL5A1-up IGF1-up|COL5A1-up JUN-down|COL5A1-up LAMA3-down|COL5A1-up MMP1-up|COL5A1-up MMP2-up|COL5A1-up PDGFRA-down|COL5A1-up TGFB3-up|COL5A2-up JUN-down|COL5A2-up LAMA3-down|COL5A2-up MMP1-up|COL5A2-up MMP2-up|COL5A2-up TGFB3-up|COL6A1-up JUN-down|COL6A1-up LAMA3-down|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A1-up PDGFRA-down|COL6A1-up TGFB3-up|COL6A1-up ZBTB16-down|COL6A3-up JUN-down|COL6A3-up LAMA3-down|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COL6A3-up PDGFRA-down|COL6A3-up TGFB3-up|COL7A1-up JUN-down|COL7A1-up LAMA3-down|COL7A1-up MMP1-up|COL7A1-up MMP2-up|MME-down CXCL12-up|MME-down EDNRB-down|MME-down IGF1-up|PRSS1-up IGF1-up|SLC1A1-down IGF1-up|KCNN4-up JUN-down|MME-down JUN-down|PRSS1-up JUN-down|MME-down MMP1-up|MME-down MMP2-up|MME-down PDGFRA-down|MME-down ZBTB16-down|PRSS1-up MMP1-up	COL18A1-up_80781 CCND1-up_595|COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|MME-down_4311 CCND1-up_595|COL10A1-up_1300 MMP1-up_4312|COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 EDNRB-down_1910|COL14A1-up_7373 FGF14-up_2259|COL14A1-up_7373 JUN-down_3725|COL14A1-up_7373 LAMA3-down_3909|COL14A1-up_7373 MMP1-up_4312|COL14A1-up_7373 MMP2-up_4313|COL14A1-up_7373 TGFB3-up_7043|COL15A1-up_1306 LAMA3-down_3909|COL15A1-up_1306 MMP2-up_4313|COL17A1-up_1308 LAMA3-down_3909|COL17A1-up_1308 MMP1-up_4312|COL17A1-up_1308 MMP2-up_4313|COL18A1-up_80781 CXCL12-up_6387|COL18A1-up_80781 EDNRB-down_1910|COL18A1-up_80781 FIGF-down_2277|COL18A1-up_80781 IGF1-up_3479|COL18A1-up_80781 JUN-down_3725|COL18A1-up_80781 LAMA3-down_3909|COL18A1-up_80781 MMP1-up_4312|COL18A1-up_80781 MMP2-up_4313|COL18A1-up_80781 TGFB3-up_7043|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 LAMA3-down_3909|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TCF7L2-up_6934|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 EDNRB-down_1910|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 LAMA3-down_3909|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 CXCL12-up_6387|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 LAMA3-down_3909|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 TGFB3-up_7043|COL5A1-up_1289 IGF1-up_3479|COL5A1-up_1289 JUN-down_3725|COL5A1-up_1289 LAMA3-down_3909|COL5A1-up_1289 MMP1-up_4312|COL5A1-up_1289 MMP2-up_4313|COL5A1-up_1289 PDGFRA-down_5156|COL5A1-up_1289 TGFB3-up_7043|COL5A2-up_1290 JUN-down_3725|COL5A2-up_1290 LAMA3-down_3909|COL5A2-up_1290 MMP1-up_4312|COL5A2-up_1290 MMP2-up_4313|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 LAMA3-down_3909|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 TGFB3-up_7043|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 LAMA3-down_3909|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 TGFB3-up_7043|COL7A1-up_1294 JUN-down_3725|COL7A1-up_1294 LAMA3-down_3909|COL7A1-up_1294 MMP1-up_4312|COL7A1-up_1294 MMP2-up_4313|MME-down_4311 CXCL12-up_6387|MME-down_4311 EDNRB-down_1910|MME-down_4311 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|SLC1A1-down_6505 IGF1-up_3479|KCNN4-up_3783 JUN-down_3725|MME-down_4311 JUN-down_3725|PRSS1-up_5644 JUN-down_3725|MME-down_4311 MMP1-up_4312|MME-down_4311 MMP2-up_4313|MME-down_4311 PDGFRA-down_5156|MME-down_4311 ZBTB16-down_7704|PRSS1-up_5644 MMP1-up_4312
hsa04974	hsa05202	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	COL1A2-up CCND2-up|COL3A1-up CCND2-up|MME-down CCND2-up|COL15A1-up PLAU-up|COL18A1-up FLT1-down|COL18A1-up IGF1-up|COL18A1-up PLAU-up|COL18A1-up PROM1-up|COL1A1-up FLT1-down|COL1A1-up IGF1-up|COL1A1-up PLAU-up|COL1A1-up PROM1-up|COL1A1-up SIX1-up|COL1A1-up ZBTB16-down|COL1A2-up FLT1-down|COL1A2-up IGF1-up|COL1A2-up PLAU-up|COL3A1-up FLT1-down|COL3A1-up IGF1-up|COL3A1-up PLAU-up|COL5A1-up FLT1-down|COL5A1-up IGF1-up|COL5A1-up PLAU-up|COL5A2-up PLAU-up|COL6A1-up ZBTB16-down|COL6A3-up PLAU-up|MME-down FLT1-down|MME-down IGF1-up|PRSS1-up IGF1-up|SLC1A1-down IGF1-up|MME-down PLAU-up|MME-down PROM1-up|MME-down ZBTB16-down|PRSS1-up PLAU-up	COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|MME-down_4311 CCND2-up_894|COL15A1-up_1306 PLAU-up_5328|COL18A1-up_80781 FLT1-down_2321|COL18A1-up_80781 IGF1-up_3479|COL18A1-up_80781 PLAU-up_5328|COL18A1-up_80781 PROM1-up_8842|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 PROM1-up_8842|COL1A1-up_1277 SIX1-up_6495|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 PLAU-up_5328|COL3A1-up_1281 FLT1-down_2321|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 PLAU-up_5328|COL5A1-up_1289 FLT1-down_2321|COL5A1-up_1289 IGF1-up_3479|COL5A1-up_1289 PLAU-up_5328|COL5A2-up_1290 PLAU-up_5328|COL6A1-up_1291 ZBTB16-down_7704|COL6A3-up_1293 PLAU-up_5328|MME-down_4311 FLT1-down_2321|MME-down_4311 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|SLC1A1-down_6505 IGF1-up_3479|MME-down_4311 PLAU-up_5328|MME-down_4311 PROM1-up_8842|MME-down_4311 ZBTB16-down_7704|PRSS1-up_5644 PLAU-up_5328
hsa04974	hsa05205	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	COL18A1-up CAV2-down|COL18A1-up CCND1-up|COL1A1-up CCND1-up|COL1A2-up CCND1-up|MME-down CCND1-up|COL10A1-up THBS1-down|COL14A1-up MMP2-up|COL14A1-up THBS1-down|COL15A1-up MMP2-up|COL15A1-up PLAU-up|COL15A1-up THBS1-down|COL17A1-up MMP2-up|COL17A1-up THBS1-down|COL18A1-up HBEGF-down|COL18A1-up IGF1-up|COL18A1-up MMP2-up|COL18A1-up PLAU-up|COL18A1-up THBS1-down|COL1A1-up IGF1-up|COL1A1-up MMP2-up|COL1A1-up PLAU-up|COL1A1-up THBS1-down|COL1A2-up IGF1-up|COL1A2-up MMP2-up|COL1A2-up PLAU-up|COL1A2-up THBS1-down|COL3A1-up IGF1-up|COL3A1-up MMP2-up|COL3A1-up PLAU-up|COL3A1-up THBS1-down|COL5A1-up IGF1-up|COL5A1-up MMP2-up|COL5A1-up PLAU-up|COL5A1-up THBS1-down|COL5A2-up MMP2-up|COL5A2-up PLAU-up|COL5A2-up THBS1-down|COL6A1-up MMP2-up|COL6A1-up THBS1-down|COL6A3-up MMP2-up|COL6A3-up PLAU-up|COL6A3-up THBS1-down|COL7A1-up HBEGF-down|COL7A1-up MMP2-up|COL7A1-up THBS1-down|MME-down IGF1-up|PRSS1-up IGF1-up|SLC1A1-down IGF1-up|MME-down MMP2-up|MME-down PLAU-up|MME-down THBS1-down|PRSS1-up PLAU-up	COL18A1-up_80781 CAV2-down_858|COL18A1-up_80781 CCND1-up_595|COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|MME-down_4311 CCND1-up_595|COL10A1-up_1300 THBS1-down_7057|COL14A1-up_7373 MMP2-up_4313|COL14A1-up_7373 THBS1-down_7057|COL15A1-up_1306 MMP2-up_4313|COL15A1-up_1306 PLAU-up_5328|COL15A1-up_1306 THBS1-down_7057|COL17A1-up_1308 MMP2-up_4313|COL17A1-up_1308 THBS1-down_7057|COL18A1-up_80781 HBEGF-down_1839|COL18A1-up_80781 IGF1-up_3479|COL18A1-up_80781 MMP2-up_4313|COL18A1-up_80781 PLAU-up_5328|COL18A1-up_80781 THBS1-down_7057|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 THBS1-down_7057|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 PLAU-up_5328|COL3A1-up_1281 THBS1-down_7057|COL5A1-up_1289 IGF1-up_3479|COL5A1-up_1289 MMP2-up_4313|COL5A1-up_1289 PLAU-up_5328|COL5A1-up_1289 THBS1-down_7057|COL5A2-up_1290 MMP2-up_4313|COL5A2-up_1290 PLAU-up_5328|COL5A2-up_1290 THBS1-down_7057|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 THBS1-down_7057|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 PLAU-up_5328|COL6A3-up_1293 THBS1-down_7057|COL7A1-up_1294 HBEGF-down_1839|COL7A1-up_1294 MMP2-up_4313|COL7A1-up_1294 THBS1-down_7057|MME-down_4311 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|SLC1A1-down_6505 IGF1-up_3479|MME-down_4311 MMP2-up_4313|MME-down_4311 PLAU-up_5328|MME-down_4311 THBS1-down_7057|PRSS1-up_5644 PLAU-up_5328
hsa04974	hsa05206	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	COL18A1-up CCND1-up|COL1A1-up CCND1-up|COL1A2-up CCND1-up|MME-down CCND1-up|COL1A2-up CCND2-up|COL3A1-up CCND2-up|MME-down CCND2-up|COL10A1-up THBS1-down|COL14A1-up THBS1-down|COL15A1-up PLAU-up|COL15A1-up THBS1-down|COL15A1-up TNC-up|COL17A1-up THBS1-down|COL17A1-up TP63-up|COL18A1-up HMOX1-down|COL18A1-up MCL1-down|COL18A1-up MMP16-up|COL18A1-up PLAU-up|COL18A1-up SERPINB5-up|COL18A1-up THBS1-down|COL18A1-up TNC-up|COL1A1-up CYP24A1-up|COL1A1-up HMOX1-down|COL1A1-up MMP16-up|COL1A1-up PDGFRA-down|COL1A1-up PLAU-up|COL1A1-up SOX4-up|COL1A1-up THBS1-down|COL1A1-up TNC-up|COL1A2-up HMOX1-down|COL1A2-up MMP16-up|COL1A2-up PDGFRA-down|COL1A2-up PLAU-up|COL1A2-up THBS1-down|COL1A2-up TNC-up|COL3A1-up MMP16-up|COL3A1-up PDGFRA-down|COL3A1-up PLAU-up|COL3A1-up THBS1-down|COL3A1-up TNC-up|COL5A1-up MMP16-up|COL5A1-up PDGFRA-down|COL5A1-up PLAU-up|COL5A1-up THBS1-down|COL5A1-up TNC-up|COL5A2-up MMP16-up|COL5A2-up PLAU-up|COL5A2-up THBS1-down|COL5A2-up TNC-up|COL6A1-up HMOX1-down|COL6A1-up MMP16-up|COL6A1-up PDGFRA-down|COL6A1-up THBS1-down|COL6A1-up TNC-up|COL6A3-up PDGFRA-down|COL6A3-up PLAU-up|COL6A3-up THBS1-down|COL6A3-up TNC-up|COL7A1-up MMP16-up|COL7A1-up THBS1-down|CPA3-up MCL1-down|MME-down HMOX1-down|MME-down MCL1-down|MME-down PDGFRA-down|MME-down PLAU-up|MME-down SERPINB5-up|MME-down THBS1-down|MME-down TP63-up|PRSS1-up PLAU-up|PRSS1-up SERPINB5-up	COL18A1-up_80781 CCND1-up_595|COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|MME-down_4311 CCND1-up_595|COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|MME-down_4311 CCND2-up_894|COL10A1-up_1300 THBS1-down_7057|COL14A1-up_7373 THBS1-down_7057|COL15A1-up_1306 PLAU-up_5328|COL15A1-up_1306 THBS1-down_7057|COL15A1-up_1306 TNC-up_3371|COL17A1-up_1308 THBS1-down_7057|COL17A1-up_1308 TP63-up_8626|COL18A1-up_80781 HMOX1-down_3162|COL18A1-up_80781 MCL1-down_4170|COL18A1-up_80781 MMP16-up_4325|COL18A1-up_80781 PLAU-up_5328|COL18A1-up_80781 SERPINB5-up_5268|COL18A1-up_80781 THBS1-down_7057|COL18A1-up_80781 TNC-up_3371|COL1A1-up_1277 CYP24A1-up_1591|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 MMP16-up_4325|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SOX4-up_6659|COL1A1-up_1277 THBS1-down_7057|COL1A1-up_1277 TNC-up_3371|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 MMP16-up_4325|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 THBS1-down_7057|COL1A2-up_1278 TNC-up_3371|COL3A1-up_1281 MMP16-up_4325|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 PLAU-up_5328|COL3A1-up_1281 THBS1-down_7057|COL3A1-up_1281 TNC-up_3371|COL5A1-up_1289 MMP16-up_4325|COL5A1-up_1289 PDGFRA-down_5156|COL5A1-up_1289 PLAU-up_5328|COL5A1-up_1289 THBS1-down_7057|COL5A1-up_1289 TNC-up_3371|COL5A2-up_1290 MMP16-up_4325|COL5A2-up_1290 PLAU-up_5328|COL5A2-up_1290 THBS1-down_7057|COL5A2-up_1290 TNC-up_3371|COL6A1-up_1291 HMOX1-down_3162|COL6A1-up_1291 MMP16-up_4325|COL6A1-up_1291 PDGFRA-down_5156|COL6A1-up_1291 THBS1-down_7057|COL6A1-up_1291 TNC-up_3371|COL6A3-up_1293 PDGFRA-down_5156|COL6A3-up_1293 PLAU-up_5328|COL6A3-up_1293 THBS1-down_7057|COL6A3-up_1293 TNC-up_3371|COL7A1-up_1294 MMP16-up_4325|COL7A1-up_1294 THBS1-down_7057|CPA3-up_1359 MCL1-down_4170|MME-down_4311 HMOX1-down_3162|MME-down_4311 MCL1-down_4170|MME-down_4311 PDGFRA-down_5156|MME-down_4311 PLAU-up_5328|MME-down_4311 SERPINB5-up_5268|MME-down_4311 THBS1-down_7057|MME-down_4311 TP63-up_8626|PRSS1-up_5644 PLAU-up_5328|PRSS1-up_5644 SERPINB5-up_5268
hsa04974	hsa05219	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	COL18A1-up CCND1-up|COL1A1-up CCND1-up|COL1A2-up CCND1-up|MME-down CCND1-up|COL10A1-up MMP1-up|COL10A1-up THBS1-down|COL14A1-up MMP1-up|COL14A1-up MMP2-up|COL14A1-up THBS1-down|COL15A1-up MMP2-up|COL15A1-up THBS1-down|COL17A1-up MMP1-up|COL17A1-up MMP2-up|COL17A1-up THBS1-down|COL18A1-up HBEGF-down|COL18A1-up MMP1-up|COL18A1-up MMP2-up|COL18A1-up THBS1-down|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up THBS1-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up THBS1-down|COL3A1-up MMP1-up|COL3A1-up MMP2-up|COL3A1-up THBS1-down|COL5A1-up MMP1-up|COL5A1-up MMP2-up|COL5A1-up THBS1-down|COL5A2-up MMP1-up|COL5A2-up MMP2-up|COL5A2-up THBS1-down|COL6A1-up MMP1-up|COL6A1-up MMP2-up|COL6A1-up THBS1-down|COL6A3-up MMP1-up|COL6A3-up MMP2-up|COL6A3-up THBS1-down|COL7A1-up HBEGF-down|COL7A1-up MMP1-up|COL7A1-up MMP2-up|COL7A1-up THBS1-down|MME-down MMP1-up|MME-down MMP2-up|MME-down THBS1-down|PRSS1-up MMP1-up	COL18A1-up_80781 CCND1-up_595|COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|MME-down_4311 CCND1-up_595|COL10A1-up_1300 MMP1-up_4312|COL10A1-up_1300 THBS1-down_7057|COL14A1-up_7373 MMP1-up_4312|COL14A1-up_7373 MMP2-up_4313|COL14A1-up_7373 THBS1-down_7057|COL15A1-up_1306 MMP2-up_4313|COL15A1-up_1306 THBS1-down_7057|COL17A1-up_1308 MMP1-up_4312|COL17A1-up_1308 MMP2-up_4313|COL17A1-up_1308 THBS1-down_7057|COL18A1-up_80781 HBEGF-down_1839|COL18A1-up_80781 MMP1-up_4312|COL18A1-up_80781 MMP2-up_4313|COL18A1-up_80781 THBS1-down_7057|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 THBS1-down_7057|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 THBS1-down_7057|COL5A1-up_1289 MMP1-up_4312|COL5A1-up_1289 MMP2-up_4313|COL5A1-up_1289 THBS1-down_7057|COL5A2-up_1290 MMP1-up_4312|COL5A2-up_1290 MMP2-up_4313|COL5A2-up_1290 THBS1-down_7057|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 MMP2-up_4313|COL6A1-up_1291 THBS1-down_7057|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 MMP2-up_4313|COL6A3-up_1293 THBS1-down_7057|COL7A1-up_1294 HBEGF-down_1839|COL7A1-up_1294 MMP1-up_4312|COL7A1-up_1294 MMP2-up_4313|COL7A1-up_1294 THBS1-down_7057|MME-down_4311 MMP1-up_4312|MME-down_4311 MMP2-up_4313|MME-down_4311 THBS1-down_7057|PRSS1-up_5644 MMP1-up_4312
hsa04974	hsa05323	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	COL10A1-up MMP1-up|COL10A1-up TGFB3-up|COL14A1-up CTSK-up|COL14A1-up JUN-down|COL14A1-up MMP1-up|COL14A1-up TGFB3-up|COL17A1-up MMP1-up|COL18A1-up CTSK-up|COL18A1-up CXCL12-up|COL18A1-up FLT1-down|COL18A1-up JUN-down|COL18A1-up MMP1-up|COL18A1-up TGFB3-up|COL1A1-up CTSK-up|COL1A1-up CXCL12-up|COL1A1-up FLT1-down|COL1A1-up JUN-down|COL1A1-up MMP1-up|COL1A1-up TGFB3-up|COL1A2-up CTSK-up|COL1A2-up CXCL12-up|COL1A2-up FLT1-down|COL1A2-up JUN-down|COL1A2-up MMP1-up|COL1A2-up TGFB3-up|COL3A1-up CTSK-up|COL3A1-up CXCL12-up|COL3A1-up FLT1-down|COL3A1-up JUN-down|COL3A1-up MMP1-up|COL3A1-up TGFB3-up|COL5A1-up CTSK-up|COL5A1-up FLT1-down|COL5A1-up JUN-down|COL5A1-up MMP1-up|COL5A1-up TGFB3-up|COL5A2-up CTSK-up|COL5A2-up JUN-down|COL5A2-up MMP1-up|COL5A2-up TGFB3-up|COL6A1-up CTSK-up|COL6A1-up JUN-down|COL6A1-up MMP1-up|COL6A1-up TGFB3-up|COL6A3-up CTSK-up|COL6A3-up JUN-down|COL6A3-up MMP1-up|COL6A3-up TGFB3-up|COL7A1-up JUN-down|COL7A1-up MMP1-up|MME-down CTSK-up|MME-down CXCL12-up|MME-down FLT1-down|KCNN4-up JUN-down|MME-down JUN-down|PRSS1-up JUN-down|MME-down MMP1-up|PRSS1-up MMP1-up	COL10A1-up_1300 MMP1-up_4312|COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 CTSK-up_1513|COL14A1-up_7373 JUN-down_3725|COL14A1-up_7373 MMP1-up_4312|COL14A1-up_7373 TGFB3-up_7043|COL17A1-up_1308 MMP1-up_4312|COL18A1-up_80781 CTSK-up_1513|COL18A1-up_80781 CXCL12-up_6387|COL18A1-up_80781 FLT1-down_2321|COL18A1-up_80781 JUN-down_3725|COL18A1-up_80781 MMP1-up_4312|COL18A1-up_80781 TGFB3-up_7043|COL1A1-up_1277 CTSK-up_1513|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 CTSK-up_1513|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 CTSK-up_1513|COL3A1-up_1281 CXCL12-up_6387|COL3A1-up_1281 FLT1-down_2321|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 TGFB3-up_7043|COL5A1-up_1289 CTSK-up_1513|COL5A1-up_1289 FLT1-down_2321|COL5A1-up_1289 JUN-down_3725|COL5A1-up_1289 MMP1-up_4312|COL5A1-up_1289 TGFB3-up_7043|COL5A2-up_1290 CTSK-up_1513|COL5A2-up_1290 JUN-down_3725|COL5A2-up_1290 MMP1-up_4312|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 CTSK-up_1513|COL6A1-up_1291 JUN-down_3725|COL6A1-up_1291 MMP1-up_4312|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 CTSK-up_1513|COL6A3-up_1293 JUN-down_3725|COL6A3-up_1293 MMP1-up_4312|COL6A3-up_1293 TGFB3-up_7043|COL7A1-up_1294 JUN-down_3725|COL7A1-up_1294 MMP1-up_4312|MME-down_4311 CTSK-up_1513|MME-down_4311 CXCL12-up_6387|MME-down_4311 FLT1-down_2321|KCNN4-up_3783 JUN-down_3725|MME-down_4311 JUN-down_3725|PRSS1-up_5644 JUN-down_3725|MME-down_4311 MMP1-up_4312|PRSS1-up_5644 MMP1-up_4312
hsa04974	hsa05410	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	COL10A1-up TGFB3-up|COL14A1-up ITGB8-up|COL14A1-up TGFB3-up|COL17A1-up ITGB4-up|COL18A1-up IGF1-up|COL18A1-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL3A1-up IGF1-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|COL3A1-up TGFB3-up|COL3A1-up TNNC1-down|COL3A1-up TTN-down|COL5A1-up IGF1-up|COL5A1-up ITGA10-down|COL5A1-up ITGB4-up|COL5A1-up ITGB8-up|COL5A1-up TGFB3-up|COL5A1-up TTN-down|COL5A2-up ITGB4-up|COL5A2-up ITGB8-up|COL5A2-up TGFB3-up|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COL7A1-up ITGB4-up|MME-down IGF1-up|PRSS1-up IGF1-up|SLC1A1-down IGF1-up|MME-down ITGB4-up	COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 ITGB8-up_3696|COL14A1-up_7373 TGFB3-up_7043|COL17A1-up_1308 ITGB4-up_3691|COL18A1-up_80781 IGF1-up_3479|COL18A1-up_80781 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|COL3A1-up_1281 TGFB3-up_7043|COL3A1-up_1281 TNNC1-down_7134|COL3A1-up_1281 TTN-down_7273|COL5A1-up_1289 IGF1-up_3479|COL5A1-up_1289 ITGA10-down_8515|COL5A1-up_1289 ITGB4-up_3691|COL5A1-up_1289 ITGB8-up_3696|COL5A1-up_1289 TGFB3-up_7043|COL5A1-up_1289 TTN-down_7273|COL5A2-up_1290 ITGB4-up_3691|COL5A2-up_1290 ITGB8-up_3696|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COL7A1-up_1294 ITGB4-up_3691|MME-down_4311 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|SLC1A1-down_6505 IGF1-up_3479|MME-down_4311 ITGB4-up_3691
hsa04974	hsa05412	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	COL17A1-up CDH2-up|COL18A1-up CDH2-up|COL1A1-up CDH2-up|COL1A2-up CDH2-up|COL3A1-up CDH2-up|COL5A1-up CDH2-up|MME-down CDH2-up|PRSS1-up CDH2-up|COL14A1-up ITGB8-up|COL17A1-up ITGB4-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TCF7L2-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|COL5A1-up ITGA10-down|COL5A1-up ITGB4-up|COL5A1-up ITGB8-up|COL5A2-up ITGB4-up|COL5A2-up ITGB8-up|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL7A1-up ITGB4-up|MME-down ITGB4-up	COL17A1-up_1308 CDH2-up_1000|COL18A1-up_80781 CDH2-up_1000|COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COL3A1-up_1281 CDH2-up_1000|COL5A1-up_1289 CDH2-up_1000|MME-down_4311 CDH2-up_1000|PRSS1-up_5644 CDH2-up_1000|COL14A1-up_7373 ITGB8-up_3696|COL17A1-up_1308 ITGB4-up_3691|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TCF7L2-up_6934|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|COL5A1-up_1289 ITGA10-down_8515|COL5A1-up_1289 ITGB4-up_3691|COL5A1-up_1289 ITGB8-up_3696|COL5A2-up_1290 ITGB4-up_3691|COL5A2-up_1290 ITGB8-up_3696|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL7A1-up_1294 ITGB4-up_3691|MME-down_4311 ITGB4-up_3691
hsa04974	hsa05414	Protein digestion and absorption - Homo sapiens (human)	MME,SLC1A1,COL10A1,COL14A1,COL15A1,COL17A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A1,COL6A3,COL7A1,CPA3,KCNN4,PRSS1	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	MME-down ADRB1-down|COL10A1-up TGFB3-up|COL14A1-up ITGB8-up|COL14A1-up TGFB3-up|COL17A1-up ITGB4-up|COL18A1-up IGF1-up|COL18A1-up TGFB3-up|COL1A1-up IGF1-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up PLN-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL3A1-up IGF1-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|COL3A1-up TGFB3-up|COL3A1-up TNNC1-down|COL3A1-up TTN-down|COL5A1-up IGF1-up|COL5A1-up ITGA10-down|COL5A1-up ITGB4-up|COL5A1-up ITGB8-up|COL5A1-up TGFB3-up|COL5A1-up TTN-down|COL5A2-up ITGB4-up|COL5A2-up ITGB8-up|COL5A2-up TGFB3-up|COL6A1-up ITGB4-up|COL6A1-up ITGB8-up|COL6A1-up TGFB3-up|COL6A3-up ITGB4-up|COL6A3-up ITGB8-up|COL6A3-up TGFB3-up|COL6A3-up TTN-down|COL7A1-up ITGB4-up|MME-down IGF1-up|PRSS1-up IGF1-up|SLC1A1-down IGF1-up|MME-down ITGB4-up	MME-down_4311 ADRB1-down_153|COL10A1-up_1300 TGFB3-up_7043|COL14A1-up_7373 ITGB8-up_3696|COL14A1-up_7373 TGFB3-up_7043|COL17A1-up_1308 ITGB4-up_3691|COL18A1-up_80781 IGF1-up_3479|COL18A1-up_80781 TGFB3-up_7043|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 PLN-up_5350|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|COL3A1-up_1281 TGFB3-up_7043|COL3A1-up_1281 TNNC1-down_7134|COL3A1-up_1281 TTN-down_7273|COL5A1-up_1289 IGF1-up_3479|COL5A1-up_1289 ITGA10-down_8515|COL5A1-up_1289 ITGB4-up_3691|COL5A1-up_1289 ITGB8-up_3696|COL5A1-up_1289 TGFB3-up_7043|COL5A1-up_1289 TTN-down_7273|COL5A2-up_1290 ITGB4-up_3691|COL5A2-up_1290 ITGB8-up_3696|COL5A2-up_1290 TGFB3-up_7043|COL6A1-up_1291 ITGB4-up_3691|COL6A1-up_1291 ITGB8-up_3696|COL6A1-up_1291 TGFB3-up_7043|COL6A3-up_1293 ITGB4-up_3691|COL6A3-up_1293 ITGB8-up_3696|COL6A3-up_1293 TGFB3-up_7043|COL6A3-up_1293 TTN-down_7273|COL7A1-up_1294 ITGB4-up_3691|MME-down_4311 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|SLC1A1-down_6505 IGF1-up_3479|MME-down_4311 ITGB4-up_3691
hsa04978	hsa05146	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	0.031	HMOX1-down COL1A1-up|TF-up COL1A1-up|HMOX1-down COL1A2-up|TF-up COL1A2-up|TF-up COL3A1-up|TF-up SERPINB3-up|TF-up TGFB3-up	HMOX1-down_3162 COL1A1-up_1277|TF-up_7018 COL1A1-up_1277|HMOX1-down_3162 COL1A2-up_1278|TF-up_7018 COL1A2-up_1278|TF-up_7018 COL3A1-up_1281|TF-up_7018 SERPINB3-up_6317|TF-up_7018 TGFB3-up_7043
hsa04978	hsa05166	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.007	HMOX1-down CCND1-up|TF-up CCND1-up|HMOX1-down CCND2-up|TF-up CCND2-up|HMOX1-down JAK1-down|HMOX1-down JUN-down|HMOX1-down MYB-up|HMOX1-down PDGFRA-down|HMOX1-down VCAM1-up|TF-up JAK1-down|MT1E-down JUN-down|MT1X-down JUN-down|MT2A-down JUN-down|TF-up JUN-down|MT2A-down VCAM1-up|TF-up MYB-up|TF-up PDGFRA-down|TF-up TGFB3-up|TF-up VCAM1-up	HMOX1-down_3162 CCND1-up_595|TF-up_7018 CCND1-up_595|HMOX1-down_3162 CCND2-up_894|TF-up_7018 CCND2-up_894|HMOX1-down_3162 JAK1-down_3716|HMOX1-down_3162 JUN-down_3725|HMOX1-down_3162 MYB-up_4602|HMOX1-down_3162 PDGFRA-down_5156|HMOX1-down_3162 VCAM1-up_7412|TF-up_7018 JAK1-down_3716|MT1E-down_4493 JUN-down_3725|MT1X-down_4501 JUN-down_3725|MT2A-down_4502 JUN-down_3725|TF-up_7018 JUN-down_3725|MT2A-down_4502 VCAM1-up_7412|TF-up_7018 MYB-up_4602|TF-up_7018 PDGFRA-down_5156|TF-up_7018 TGFB3-up_7043|TF-up_7018 VCAM1-up_7412
hsa04978	hsa05200	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.022	HMOX1-down CCND1-up|TF-up CCND1-up|HMOX1-down CXCL12-up|TF-up CXCL12-up|HMOX1-down EDNRB-down|TF-up EDNRB-down|HMOX1-down FIGF-down|HMOX1-down IGF1-up|HMOX1-down JAK1-down|HMOX1-down JUN-down|HMOX1-down MMP1-up|HMOX1-down MMP2-up|HMOX1-down PDGFRA-down|TF-up IGF1-up|TF-up JAK1-down|MT1E-down JUN-down|MT1X-down JUN-down|MT2A-down JUN-down|TF-up JUN-down|TF-up MMP1-up|MT1E-down MMP2-up|TF-up MMP2-up|TF-up PDGFRA-down|TF-up TGFB3-up	HMOX1-down_3162 CCND1-up_595|TF-up_7018 CCND1-up_595|HMOX1-down_3162 CXCL12-up_6387|TF-up_7018 CXCL12-up_6387|HMOX1-down_3162 EDNRB-down_1910|TF-up_7018 EDNRB-down_1910|HMOX1-down_3162 FIGF-down_2277|HMOX1-down_3162 IGF1-up_3479|HMOX1-down_3162 JAK1-down_3716|HMOX1-down_3162 JUN-down_3725|HMOX1-down_3162 MMP1-up_4312|HMOX1-down_3162 MMP2-up_4313|HMOX1-down_3162 PDGFRA-down_5156|TF-up_7018 IGF1-up_3479|TF-up_7018 JAK1-down_3716|MT1E-down_4493 JUN-down_3725|MT1X-down_4501 JUN-down_3725|MT2A-down_4502 JUN-down_3725|TF-up_7018 JUN-down_3725|TF-up_7018 MMP1-up_4312|MT1E-down_4493 MMP2-up_4313|TF-up_7018 MMP2-up_4313|TF-up_7018 PDGFRA-down_5156|TF-up_7018 TGFB3-up_7043
hsa04978	hsa05205	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.022	HMOX1-down CAV2-down|TF-up CAV2-down|HMOX1-down CCND1-up|TF-up CCND1-up|HMOX1-down HBEGF-down|TF-up HBEGF-down|HMOX1-down IGF1-up|HMOX1-down MMP2-up|HMOX1-down PLAU-up|HMOX1-down THBS1-down|TF-up IGF1-up|MT1E-down MMP2-up|TF-up MMP2-up|TF-up PLAU-up|TF-up THBS1-down	HMOX1-down_3162 CAV2-down_858|TF-up_7018 CAV2-down_858|HMOX1-down_3162 CCND1-up_595|TF-up_7018 CCND1-up_595|HMOX1-down_3162 HBEGF-down_1839|TF-up_7018 HBEGF-down_1839|HMOX1-down_3162 IGF1-up_3479|HMOX1-down_3162 MMP2-up_4313|HMOX1-down_3162 PLAU-up_5328|HMOX1-down_3162 THBS1-down_7057|TF-up_7018 IGF1-up_3479|MT1E-down_4493 MMP2-up_4313|TF-up_7018 MMP2-up_4313|TF-up_7018 PLAU-up_5328|TF-up_7018 THBS1-down_7057
hsa04978	hsa05323	Mineral absorption - Homo sapiens (human)	HMOX1,MT1E,MT1G,MT1M,MT1X,MT2A,TF	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.003	HMOX1-down CTSK-up|HMOX1-down CXCL12-up|TF-up CXCL12-up|HMOX1-down FLT1-down|TF-up FLT1-down|HMOX1-down JUN-down|HMOX1-down MMP1-up|MT1E-down JUN-down|MT1X-down JUN-down|MT2A-down JUN-down|TF-up JUN-down|TF-up MMP1-up|TF-up TGFB3-up	HMOX1-down_3162 CTSK-up_1513|HMOX1-down_3162 CXCL12-up_6387|TF-up_7018 CXCL12-up_6387|HMOX1-down_3162 FLT1-down_2321|TF-up_7018 FLT1-down_2321|HMOX1-down_3162 JUN-down_3725|HMOX1-down_3162 MMP1-up_4312|MT1E-down_4493 JUN-down_3725|MT1X-down_4501 JUN-down_3725|MT2A-down_4502 JUN-down_3725|TF-up_7018 JUN-down_3725|TF-up_7018 MMP1-up_4312|TF-up_7018 TGFB3-up_7043
hsa05145	hsa05202	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.048	JAK1-down CCND2-up|TGFB3-up CCND2-up|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JAK1-down FLT1-down|LDLR-down FLT1-down|TGFB3-up FLT1-down|HSPA1A-down IGF1-up|HSPA1B-down ZBTB16-down|JAK1-down IGF1-up|LDLR-down IGF1-up|TGFB3-up IGF1-up|JAK1-down PLAU-up|JAK1-down ZBTB16-down|LAMA3-down PLAU-up|TGFB3-up PLAU-up|TGFB3-up SIX1-up	JAK1-down_3716 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|LDLR-down_3949 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|HSPA1A-down_3303 IGF1-up_3479|HSPA1B-down_3304 ZBTB16-down_7704|JAK1-down_3716 IGF1-up_3479|LDLR-down_3949 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|LAMA3-down_3909 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SIX1-up_6495
hsa05145	hsa05205	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.001	LAMA3-down CAV2-down|HSPA1A-down CCND1-up|JAK1-down CCND1-up|LAMA3-down CCND1-up|LDLR-down CCND1-up|TGFB3-up CCND1-up|LAMA3-down HBEGF-down|TGFB3-up HBEGF-down|HSPA1A-down IGF1-up|JAK1-down IGF1-up|LDLR-down IGF1-up|TGFB3-up IGF1-up|JAK1-down MMP2-up|JAK1-down PLAU-up|LAMA3-down MMP2-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|LDLR-down MMP2-up|LDLR-down THBS1-down|TGFB3-up MMP2-up|TGFB3-up PLAU-up|TGFB3-up THBS1-down	LAMA3-down_3909 CAV2-down_858|HSPA1A-down_3303 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|LDLR-down_3949 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|LAMA3-down_3909 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|HSPA1A-down_3303 IGF1-up_3479|JAK1-down_3716 IGF1-up_3479|LDLR-down_3949 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 THBS1-down_7057|TGFB3-up_7043 MMP2-up_4313|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057
hsa05145	hsa05206	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.002	HSPA1A-down CCND1-up|JAK1-down CCND1-up|LAMA3-down CCND1-up|LDLR-down CCND1-up|TGFB3-up CCND1-up|JAK1-down CCND2-up|TGFB3-up CCND2-up|LDLR-down CYP24A1-up|HSPA1A-down HMOX1-down|HSPA1B-down HMOX1-down|JAK1-down HMOX1-down|LDLR-down HMOX1-down|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|JAK1-down IRS2-down|LDLR-down IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|LAMA3-down TNC-up|LDLR-down THBS1-down|LDLR-down TNC-up|TGFB3-up PDGFRA-down|TGFB3-up PLAU-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	HSPA1A-down_3303 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|LDLR-down_3949 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|JAK1-down_3716 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|LDLR-down_3949 CYP24A1-up_1591|HSPA1A-down_3303 HMOX1-down_3162|HSPA1B-down_3304 HMOX1-down_3162|JAK1-down_3716 HMOX1-down_3162|LDLR-down_3949 HMOX1-down_3162|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|JAK1-down_3716 IRS2-down_8660|LDLR-down_3949 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|LAMA3-down_3909 TNC-up_3371|LDLR-down_3949 THBS1-down_7057|LDLR-down_3949 TNC-up_3371|TGFB3-up_7043 PDGFRA-down_5156|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa05145	hsa05219	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	HSPA1A-down CCND1-up|JAK1-down CCND1-up|LAMA3-down CCND1-up|LDLR-down CCND1-up|TGFB3-up CCND1-up|LAMA3-down HBEGF-down|TGFB3-up HBEGF-down|JAK1-down MMP1-up|JAK1-down MMP2-up|LAMA3-down MMP1-up|LAMA3-down MMP2-up|LAMA3-down THBS1-down|LDLR-down MMP1-up|LDLR-down MMP2-up|LDLR-down THBS1-down|TGFB3-up MMP1-up|TGFB3-up MMP2-up|TGFB3-up THBS1-down	HSPA1A-down_3303 CCND1-up_595|JAK1-down_3716 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|LDLR-down_3949 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|LAMA3-down_3909 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|LAMA3-down_3909 MMP1-up_4312|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 THBS1-down_7057|LDLR-down_3949 MMP1-up_4312|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 THBS1-down_7057|TGFB3-up_7043 MMP1-up_4312|TGFB3-up_7043 MMP2-up_4313|TGFB3-up_7043 THBS1-down_7057
hsa05145	hsa05412	Toxoplasmosis - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,LAMA3,LDLR,HLA-DOA,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.012	JAK1-down CDH2-up|TGFB3-up CDH2-up|TGFB3-up DES-up|LAMA3-down ITGA10-down|LAMA3-down ITGB4-up|LAMA3-down ITGB8-up|TGFB3-up ITGB8-up|LDLR-down TCF7L2-up|TGFB3-up TCF7L2-up	JAK1-down_3716 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|LAMA3-down_3909 ITGA10-down_8515|LAMA3-down_3909 ITGB4-up_3691|LAMA3-down_3909 ITGB8-up_3696|TGFB3-up_7043 ITGB8-up_3696|LDLR-down_3949 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934
hsa05146	hsa05152	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	0	COL1A1-up CD74-up|COL1A2-up CD74-up|COL3A1-up CD74-up|IL1R2-down CLEC4E-down|COL1A1-up TGFB3-up|COL1A2-up JAK1-down|COL1A2-up TGFB3-up|COL3A1-up TGFB3-up	COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|COL3A1-up_1281 CD74-up_972|IL1R2-down_7850 CLEC4E-down_26253|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 TGFB3-up_7043
hsa05146	hsa05160	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	0.019	COL1A1-up CLDN1-up|COL1A2-up CLDN1-up|COL3A1-up CLDN1-up|COL1A1-up LDLR-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|IL1R2-down SOCS3-down	COL1A1-up_1277 CLDN1-up_9076|COL1A2-up_1278 CLDN1-up_9076|COL3A1-up_1281 CLDN1-up_9076|COL1A1-up_1277 LDLR-down_3949|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|IL1R2-down_7850 SOCS3-down_9021
hsa05146	hsa05166	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	0.011	COL1A1-up CCND1-up|COL1A2-up CCND1-up|LAMA3-down CCND1-up|COL1A2-up CCND2-up|COL3A1-up CCND2-up|COL1A1-up JUN-down|COL1A1-up MYB-up|COL1A1-up PDGFRA-down|COL1A1-up TGFB3-up|COL1A1-up VCAM1-up|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL1A2-up MYB-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL3A1-up JUN-down|COL3A1-up PDGFRA-down|COL3A1-up TGFB3-up|LAMA3-down JUN-down|SERPINB3-up JUN-down|LAMA3-down VCAM1-up	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MYB-up_4602|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 VCAM1-up_7412|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MYB-up_4602|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 TGFB3-up_7043|LAMA3-down_3909 JUN-down_3725|SERPINB3-up_6317 JUN-down_3725|LAMA3-down_3909 VCAM1-up_7412
hsa05146	hsa05168	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	0	COL1A1-up CD74-up|COL1A2-up CD74-up|COL3A1-up CD74-up|COL1A1-up JUN-down|COL1A1-up SOCS3-down|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL3A1-up JUN-down|IL1R2-down SOCS3-down|LAMA3-down JUN-down|SERPINB3-up JUN-down|TGFB3-up JUN-down	COL1A1-up_1277 CD74-up_972|COL1A2-up_1278 CD74-up_972|COL3A1-up_1281 CD74-up_972|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 SOCS3-down_9021|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL3A1-up_1281 JUN-down_3725|IL1R2-down_7850 SOCS3-down_9021|LAMA3-down_3909 JUN-down_3725|SERPINB3-up_6317 JUN-down_3725|TGFB3-up_7043 JUN-down_3725
hsa05146	hsa05200	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.008	COL1A1-up CCND1-up|COL1A2-up CCND1-up|COL1A1-up CXCL12-up|COL1A1-up FIGF-down|COL1A1-up IGF1-up|COL1A1-up JUN-down|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up PDGFRA-down|COL1A1-up TCF7L2-up|COL1A1-up TGFB3-up|COL1A1-up ZBTB16-down|COL1A2-up CXCL12-up|COL1A2-up EDNRB-down|COL1A2-up FIGF-down|COL1A2-up IGF1-up|COL1A2-up JAK1-down|COL1A2-up JUN-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up PDGFRA-down|COL1A2-up TGFB3-up|COL3A1-up CXCL12-up|COL3A1-up IGF1-up|COL3A1-up JUN-down|COL3A1-up MMP1-up|COL3A1-up MMP2-up|COL3A1-up PDGFRA-down|COL3A1-up TGFB3-up|SERPINB3-up JUN-down|SERPINB3-up MMP2-up	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 FIGF-down_2277|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 TCF7L2-up_6934|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 EDNRB-down_1910|COL1A2-up_1278 FIGF-down_2277|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 JAK1-down_3716|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 CXCL12-up_6387|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 TGFB3-up_7043|SERPINB3-up_6317 JUN-down_3725|SERPINB3-up_6317 MMP2-up_4313
hsa05146	hsa05202	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	COL1A2-up CCND2-up|COL3A1-up CCND2-up|TGFB3-up CCND2-up|COL1A1-up FLT1-down|COL1A1-up IGF1-up|COL1A1-up PLAU-up|COL1A1-up PROM1-up|COL1A1-up SIX1-up|COL1A1-up ZBTB16-down|COL1A2-up FLT1-down|COL1A2-up IGF1-up|COL1A2-up PLAU-up|COL3A1-up FLT1-down|COL3A1-up IGF1-up|COL3A1-up PLAU-up|TGFB3-up FLT1-down|TGFB3-up IGF1-up|LAMA3-down PLAU-up|SERPINB3-up PLAU-up|TGFB3-up PLAU-up|TGFB3-up SIX1-up	COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 PROM1-up_8842|COL1A1-up_1277 SIX1-up_6495|COL1A1-up_1277 ZBTB16-down_7704|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 PLAU-up_5328|COL3A1-up_1281 FLT1-down_2321|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 PLAU-up_5328|TGFB3-up_7043 FLT1-down_2321|TGFB3-up_7043 IGF1-up_3479|LAMA3-down_3909 PLAU-up_5328|SERPINB3-up_6317 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SIX1-up_6495
hsa05146	hsa05205	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	LAMA3-down CAV2-down|COL1A1-up CCND1-up|COL1A2-up CCND1-up|LAMA3-down CCND1-up|TGFB3-up CCND1-up|COL1A1-up IGF1-up|COL1A1-up MMP2-up|COL1A1-up PLAU-up|COL1A1-up THBS1-down|COL1A2-up IGF1-up|COL1A2-up MMP2-up|COL1A2-up PLAU-up|COL1A2-up THBS1-down|COL3A1-up IGF1-up|COL3A1-up MMP2-up|COL3A1-up PLAU-up|COL3A1-up THBS1-down|IL1R2-down HBEGF-down|LAMA3-down HBEGF-down|TGFB3-up HBEGF-down|TGFB3-up IGF1-up|LAMA3-down MMP2-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|SERPINB3-up MMP2-up|TGFB3-up MMP2-up|SERPINB3-up PLAU-up|TGFB3-up PLAU-up|TGFB3-up THBS1-down	LAMA3-down_3909 CAV2-down_858|COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 THBS1-down_7057|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 PLAU-up_5328|COL3A1-up_1281 THBS1-down_7057|IL1R2-down_7850 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|TGFB3-up_7043 IGF1-up_3479|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|SERPINB3-up_6317 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|SERPINB3-up_6317 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057
hsa05146	hsa05206	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	COL1A1-up CCND1-up|COL1A2-up CCND1-up|LAMA3-down CCND1-up|TGFB3-up CCND1-up|COL1A2-up CCND2-up|COL3A1-up CCND2-up|TGFB3-up CCND2-up|COL1A1-up CYP24A1-up|COL1A1-up HMOX1-down|COL1A1-up MMP16-up|COL1A1-up PDGFRA-down|COL1A1-up PLAU-up|COL1A1-up SOX4-up|COL1A1-up THBS1-down|COL1A1-up TNC-up|COL1A2-up HMOX1-down|COL1A2-up MMP16-up|COL1A2-up PDGFRA-down|COL1A2-up PLAU-up|COL1A2-up THBS1-down|COL1A2-up TNC-up|COL3A1-up MMP16-up|COL3A1-up PDGFRA-down|COL3A1-up PLAU-up|COL3A1-up THBS1-down|COL3A1-up TNC-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|LAMA3-down TNC-up|SERPINB3-up MCL1-down|TGFB3-up PDGFRA-down|SERPINB3-up PLAU-up|TGFB3-up PLAU-up|SERPINB3-up SERPINB5-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|COL1A2-up_1278 CCND2-up_894|COL3A1-up_1281 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|COL1A1-up_1277 CYP24A1-up_1591|COL1A1-up_1277 HMOX1-down_3162|COL1A1-up_1277 MMP16-up_4325|COL1A1-up_1277 PDGFRA-down_5156|COL1A1-up_1277 PLAU-up_5328|COL1A1-up_1277 SOX4-up_6659|COL1A1-up_1277 THBS1-down_7057|COL1A1-up_1277 TNC-up_3371|COL1A2-up_1278 HMOX1-down_3162|COL1A2-up_1278 MMP16-up_4325|COL1A2-up_1278 PDGFRA-down_5156|COL1A2-up_1278 PLAU-up_5328|COL1A2-up_1278 THBS1-down_7057|COL1A2-up_1278 TNC-up_3371|COL3A1-up_1281 MMP16-up_4325|COL3A1-up_1281 PDGFRA-down_5156|COL3A1-up_1281 PLAU-up_5328|COL3A1-up_1281 THBS1-down_7057|COL3A1-up_1281 TNC-up_3371|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|LAMA3-down_3909 TNC-up_3371|SERPINB3-up_6317 MCL1-down_4170|TGFB3-up_7043 PDGFRA-down_5156|SERPINB3-up_6317 PLAU-up_5328|TGFB3-up_7043 PLAU-up_5328|SERPINB3-up_6317 SERPINB5-up_5268|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa05146	hsa05219	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	COL1A1-up CCND1-up|COL1A2-up CCND1-up|LAMA3-down CCND1-up|TGFB3-up CCND1-up|COL1A1-up MMP1-up|COL1A1-up MMP2-up|COL1A1-up THBS1-down|COL1A2-up MMP1-up|COL1A2-up MMP2-up|COL1A2-up THBS1-down|COL3A1-up MMP1-up|COL3A1-up MMP2-up|COL3A1-up THBS1-down|IL1R2-down HBEGF-down|LAMA3-down HBEGF-down|TGFB3-up HBEGF-down|LAMA3-down MMP1-up|LAMA3-down MMP2-up|LAMA3-down THBS1-down|TGFB3-up MMP1-up|SERPINB3-up MMP2-up|TGFB3-up MMP2-up|TGFB3-up THBS1-down	COL1A1-up_1277 CCND1-up_595|COL1A2-up_1278 CCND1-up_595|LAMA3-down_3909 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 MMP2-up_4313|COL1A1-up_1277 THBS1-down_7057|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 MMP2-up_4313|COL1A2-up_1278 THBS1-down_7057|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 MMP2-up_4313|COL3A1-up_1281 THBS1-down_7057|IL1R2-down_7850 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|LAMA3-down_3909 MMP1-up_4312|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 THBS1-down_7057|TGFB3-up_7043 MMP1-up_4312|SERPINB3-up_6317 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|TGFB3-up_7043 THBS1-down_7057
hsa05146	hsa05323	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	COL1A1-up CTSK-up|COL1A1-up CXCL12-up|COL1A1-up FLT1-down|COL1A1-up JUN-down|COL1A1-up MMP1-up|COL1A1-up TGFB3-up|COL1A2-up CTSK-up|COL1A2-up CXCL12-up|COL1A2-up FLT1-down|COL1A2-up JUN-down|COL1A2-up MMP1-up|COL1A2-up TGFB3-up|COL3A1-up CTSK-up|COL3A1-up CXCL12-up|COL3A1-up FLT1-down|COL3A1-up JUN-down|COL3A1-up MMP1-up|COL3A1-up TGFB3-up|SERPINB3-up CTSK-up|LAMA3-down JUN-down|SERPINB3-up JUN-down|LAMA3-down MMP1-up	COL1A1-up_1277 CTSK-up_1513|COL1A1-up_1277 CXCL12-up_6387|COL1A1-up_1277 FLT1-down_2321|COL1A1-up_1277 JUN-down_3725|COL1A1-up_1277 MMP1-up_4312|COL1A1-up_1277 TGFB3-up_7043|COL1A2-up_1278 CTSK-up_1513|COL1A2-up_1278 CXCL12-up_6387|COL1A2-up_1278 FLT1-down_2321|COL1A2-up_1278 JUN-down_3725|COL1A2-up_1278 MMP1-up_4312|COL1A2-up_1278 TGFB3-up_7043|COL3A1-up_1281 CTSK-up_1513|COL3A1-up_1281 CXCL12-up_6387|COL3A1-up_1281 FLT1-down_2321|COL3A1-up_1281 JUN-down_3725|COL3A1-up_1281 MMP1-up_4312|COL3A1-up_1281 TGFB3-up_7043|SERPINB3-up_6317 CTSK-up_1513|LAMA3-down_3909 JUN-down_3725|SERPINB3-up_6317 JUN-down_3725|LAMA3-down_3909 MMP1-up_4312
hsa05146	hsa05410	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	COL1A1-up IGF1-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL3A1-up IGF1-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|COL3A1-up TGFB3-up|COL3A1-up TNNC1-down|COL3A1-up TTN-down|LAMA3-down ITGA10-down|LAMA3-down ITGB4-up|LAMA3-down ITGB8-up	COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|COL3A1-up_1281 TGFB3-up_7043|COL3A1-up_1281 TNNC1-down_7134|COL3A1-up_1281 TTN-down_7273|LAMA3-down_3909 ITGA10-down_8515|LAMA3-down_3909 ITGB4-up_3691|LAMA3-down_3909 ITGB8-up_3696
hsa05146	hsa05412	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	COL1A1-up CDH2-up|COL1A2-up CDH2-up|COL3A1-up CDH2-up|TGFB3-up CDH2-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up TCF7L2-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|TGFB3-up DES-up|LAMA3-down ITGA10-down|LAMA3-down ITGB4-up|LAMA3-down ITGB8-up|TGFB3-up ITGB8-up|TGFB3-up TCF7L2-up	COL1A1-up_1277 CDH2-up_1000|COL1A2-up_1278 CDH2-up_1000|COL3A1-up_1281 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 TCF7L2-up_6934|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|TGFB3-up_7043 DES-up_1674|LAMA3-down_3909 ITGA10-down_8515|LAMA3-down_3909 ITGB4-up_3691|LAMA3-down_3909 ITGB8-up_3696|TGFB3-up_7043 ITGB8-up_3696|TGFB3-up_7043 TCF7L2-up_6934
hsa05146	hsa05414	Amoebiasis - Homo sapiens (human)	IL1R2,LAMA3,COL1A1,COL1A2,COL3A1,SERPINB3,TGFB3	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	COL1A1-up IGF1-up|COL1A1-up ITGA10-down|COL1A1-up ITGB4-up|COL1A1-up ITGB8-up|COL1A1-up PLN-up|COL1A1-up TGFB3-up|COL1A1-up TTN-down|COL1A2-up IGF1-up|COL1A2-up ITGB4-up|COL1A2-up ITGB8-up|COL1A2-up TGFB3-up|COL1A2-up TTN-down|COL3A1-up IGF1-up|COL3A1-up ITGB4-up|COL3A1-up ITGB8-up|COL3A1-up TGFB3-up|COL3A1-up TNNC1-down|COL3A1-up TTN-down|LAMA3-down ITGA10-down|LAMA3-down ITGB4-up|LAMA3-down ITGB8-up	COL1A1-up_1277 IGF1-up_3479|COL1A1-up_1277 ITGA10-down_8515|COL1A1-up_1277 ITGB4-up_3691|COL1A1-up_1277 ITGB8-up_3696|COL1A1-up_1277 PLN-up_5350|COL1A1-up_1277 TGFB3-up_7043|COL1A1-up_1277 TTN-down_7273|COL1A2-up_1278 IGF1-up_3479|COL1A2-up_1278 ITGB4-up_3691|COL1A2-up_1278 ITGB8-up_3696|COL1A2-up_1278 TGFB3-up_7043|COL1A2-up_1278 TTN-down_7273|COL3A1-up_1281 IGF1-up_3479|COL3A1-up_1281 ITGB4-up_3691|COL3A1-up_1281 ITGB8-up_3696|COL3A1-up_1281 TGFB3-up_7043|COL3A1-up_1281 TNNC1-down_7134|COL3A1-up_1281 TTN-down_7273|LAMA3-down_3909 ITGA10-down_8515|LAMA3-down_3909 ITGB4-up_3691|LAMA3-down_3909 ITGB8-up_3696
hsa05152	hsa05202	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	JAK1-down CCND2-up|TGFB3-up CCND2-up|CD74-up IGF1-up|CLEC4E-down IL1R2-down|CLEC4E-down NFKBIZ-down|CLEC4E-down PLAU-up|JAK1-down FLT1-down|TGFB3-up FLT1-down|JAK1-down IGF1-up|TGFB3-up IGF1-up|JAK1-down PLAU-up|JAK1-down ZBTB16-down|TGFB3-up PLAU-up|TGFB3-up SIX1-up	JAK1-down_3716 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD74-up_972 IGF1-up_3479|CLEC4E-down_26253 IL1R2-down_7850|CLEC4E-down_26253 NFKBIZ-down_64332|CLEC4E-down_26253 PLAU-up_5328|JAK1-down_3716 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|JAK1-down_3716 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SIX1-up_6495
hsa05152	hsa05205	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.002	CD74-up CCND1-up|JAK1-down CCND1-up|TGFB3-up CCND1-up|CD74-up IGF1-up|CD74-up MMP2-up|CD74-up THBS1-down|CLEC4E-down PLAU-up|TGFB3-up HBEGF-down|JAK1-down IGF1-up|TGFB3-up IGF1-up|JAK1-down MMP2-up|JAK1-down PLAU-up|TGFB3-up MMP2-up|TGFB3-up PLAU-up|TGFB3-up THBS1-down	CD74-up_972 CCND1-up_595|JAK1-down_3716 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CD74-up_972 IGF1-up_3479|CD74-up_972 MMP2-up_4313|CD74-up_972 THBS1-down_7057|CLEC4E-down_26253 PLAU-up_5328|TGFB3-up_7043 HBEGF-down_1839|JAK1-down_3716 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|TGFB3-up_7043 MMP2-up_4313|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057
hsa05152	hsa05206	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.004	CD74-up CCND1-up|JAK1-down CCND1-up|TGFB3-up CCND1-up|JAK1-down CCND2-up|TGFB3-up CCND2-up|CD74-up HMOX1-down|CD74-up THBS1-down|CD74-up TP63-up|CLEC4E-down PLAU-up|JAK1-down HMOX1-down|JAK1-down IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|TGFB3-up PDGFRA-down|TGFB3-up PLAU-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up	CD74-up_972 CCND1-up_595|JAK1-down_3716 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|JAK1-down_3716 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CD74-up_972 HMOX1-down_3162|CD74-up_972 THBS1-down_7057|CD74-up_972 TP63-up_8626|CLEC4E-down_26253 PLAU-up_5328|JAK1-down_3716 HMOX1-down_3162|JAK1-down_3716 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|TGFB3-up_7043 PDGFRA-down_5156|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626
hsa05152	hsa05219	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.008	CD74-up CCND1-up|JAK1-down CCND1-up|TGFB3-up CCND1-up|CD74-up MMP2-up|CD74-up THBS1-down|TGFB3-up HBEGF-down|JAK1-down MMP1-up|JAK1-down MMP2-up|TGFB3-up MMP1-up|TGFB3-up MMP2-up|TGFB3-up THBS1-down	CD74-up_972 CCND1-up_595|JAK1-down_3716 CCND1-up_595|TGFB3-up_7043 CCND1-up_595|CD74-up_972 MMP2-up_4313|CD74-up_972 THBS1-down_7057|TGFB3-up_7043 HBEGF-down_1839|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|TGFB3-up_7043 MMP1-up_4312|TGFB3-up_7043 MMP2-up_4313|TGFB3-up_7043 THBS1-down_7057
hsa05152	hsa05412	Tuberculosis - Homo sapiens (human)	CLEC4E,JAK1,CD74,HLA-DOA,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.005	CD74-up CDH2-up|JAK1-down CDH2-up|TGFB3-up CDH2-up|TGFB3-up DES-up|TGFB3-up ITGB8-up|TGFB3-up TCF7L2-up	CD74-up_972 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|TGFB3-up_7043 ITGB8-up_3696|TGFB3-up_7043 TCF7L2-up_6934
hsa05160	hsa05200	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	0.015	LDLR-down CCND1-up|SOCS3-down CCND1-up|CLDN1-up EDNRB-down|CLDN1-up MMP1-up|CLDN1-up MMP2-up|CLDN1-up TCF7L2-up|CLDN5-down CXCL12-up|CLDN5-down EDNRB-down|CLDN5-down FIGF-down|CLDN5-down IGF1-up|CLDN5-down JUN-down|CLDN5-down MMP1-up|CLDN5-down MMP2-up|CLDN5-down TCF7L2-up|SOCS3-down CSF3R-down|LDLR-down CXCL12-up|SOCS3-down CXCL12-up|LDLR-down IGF1-up|SOCS3-down IGF1-up|LDLR-down JUN-down|SOCS3-down JUN-down|LDLR-down MMP1-up|LDLR-down MMP2-up|LDLR-down TCF7L2-up|SOCS3-down MMP1-up|SOCS3-down MMP2-up|SOCS3-down PDGFRA-down	LDLR-down_3949 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CLDN1-up_9076 EDNRB-down_1910|CLDN1-up_9076 MMP1-up_4312|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 TCF7L2-up_6934|CLDN5-down_7122 CXCL12-up_6387|CLDN5-down_7122 EDNRB-down_1910|CLDN5-down_7122 FIGF-down_2277|CLDN5-down_7122 IGF1-up_3479|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MMP1-up_4312|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 TCF7L2-up_6934|SOCS3-down_9021 CSF3R-down_1441|LDLR-down_3949 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|LDLR-down_3949 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|LDLR-down_3949 JUN-down_3725|SOCS3-down_9021 JUN-down_3725|LDLR-down_3949 MMP1-up_4312|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 TCF7L2-up_6934|SOCS3-down_9021 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 PDGFRA-down_5156
hsa05160	hsa05202	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	JAK1-down CCND2-up|SOCS3-down CCND2-up|CLDN1-up PLAU-up|CLDN5-down FLT1-down|CLDN5-down IGF1-up|JAK1-down FLT1-down|LDLR-down FLT1-down|SOCS3-down FLT1-down|JAK1-down IGF1-up|LDLR-down IGF1-up|SOCS3-down IGF1-up|SOCS3-down IL1R2-down|JAK1-down PLAU-up|JAK1-down ZBTB16-down|SOCS3-down NFKBIZ-down|SOCS3-down PLAU-up	JAK1-down_3716 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CLDN1-up_9076 PLAU-up_5328|CLDN5-down_7122 FLT1-down_2321|CLDN5-down_7122 IGF1-up_3479|JAK1-down_3716 FLT1-down_2321|LDLR-down_3949 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|JAK1-down_3716 IGF1-up_3479|LDLR-down_3949 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|SOCS3-down_9021 IL1R2-down_7850|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|SOCS3-down_9021 NFKBIZ-down_64332|SOCS3-down_9021 PLAU-up_5328
hsa05160	hsa05205	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	JAK1-down CCND1-up|LDLR-down CCND1-up|SOCS3-down CCND1-up|CLDN1-up MMP2-up|CLDN1-up PLAU-up|CLDN1-up THBS1-down|CLDN5-down IGF1-up|CLDN5-down MMP2-up|CLDN5-down THBS1-down|SOCS3-down HBEGF-down|JAK1-down IGF1-up|LDLR-down IGF1-up|SOCS3-down IGF1-up|JAK1-down MMP2-up|JAK1-down PLAU-up|LDLR-down MMP2-up|LDLR-down THBS1-down|SOCS3-down MMP2-up|SOCS3-down PLAU-up|SOCS3-down THBS1-down	JAK1-down_3716 CCND1-up_595|LDLR-down_3949 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 PLAU-up_5328|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 IGF1-up_3479|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 THBS1-down_7057|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 IGF1-up_3479|LDLR-down_3949 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 THBS1-down_7057|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057
hsa05160	hsa05206	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	JAK1-down CCND1-up|LDLR-down CCND1-up|SOCS3-down CCND1-up|JAK1-down CCND2-up|SOCS3-down CCND2-up|CLDN18-down SERPINB5-up|CLDN1-up PLAU-up|CLDN1-up THBS1-down|CLDN5-down HMOX1-down|CLDN5-down THBS1-down|LDLR-down CYP24A1-up|SOCS3-down CYP24A1-up|JAK1-down HMOX1-down|LDLR-down HMOX1-down|SOCS3-down HMOX1-down|JAK1-down IRS2-down|LDLR-down IRS2-down|SOCS3-down IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|LDLR-down THBS1-down|LDLR-down TNC-up|SOCS3-down MCL1-down|SOCS3-down PDGFRA-down|SOCS3-down PLAU-up|SOCS3-down THBS1-down|SOCS3-down TNC-up	JAK1-down_3716 CCND1-up_595|LDLR-down_3949 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|JAK1-down_3716 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CLDN18-down_51208 SERPINB5-up_5268|CLDN1-up_9076 PLAU-up_5328|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 HMOX1-down_3162|CLDN5-down_7122 THBS1-down_7057|LDLR-down_3949 CYP24A1-up_1591|SOCS3-down_9021 CYP24A1-up_1591|JAK1-down_3716 HMOX1-down_3162|LDLR-down_3949 HMOX1-down_3162|SOCS3-down_9021 HMOX1-down_3162|JAK1-down_3716 IRS2-down_8660|LDLR-down_3949 IRS2-down_8660|SOCS3-down_9021 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|LDLR-down_3949 THBS1-down_7057|LDLR-down_3949 TNC-up_3371|SOCS3-down_9021 MCL1-down_4170|SOCS3-down_9021 PDGFRA-down_5156|SOCS3-down_9021 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057|SOCS3-down_9021 TNC-up_3371
hsa05160	hsa05219	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	JAK1-down CCND1-up|LDLR-down CCND1-up|SOCS3-down CCND1-up|CLDN1-up MMP1-up|CLDN1-up MMP2-up|CLDN1-up THBS1-down|CLDN5-down MMP1-up|CLDN5-down MMP2-up|CLDN5-down THBS1-down|SOCS3-down HBEGF-down|JAK1-down MMP1-up|JAK1-down MMP2-up|LDLR-down MMP1-up|LDLR-down MMP2-up|LDLR-down THBS1-down|SOCS3-down MMP1-up|SOCS3-down MMP2-up|SOCS3-down THBS1-down	JAK1-down_3716 CCND1-up_595|LDLR-down_3949 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CLDN1-up_9076 MMP1-up_4312|CLDN1-up_9076 MMP2-up_4313|CLDN1-up_9076 THBS1-down_7057|CLDN5-down_7122 MMP1-up_4312|CLDN5-down_7122 MMP2-up_4313|CLDN5-down_7122 THBS1-down_7057|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|LDLR-down_3949 MMP1-up_4312|LDLR-down_3949 MMP2-up_4313|LDLR-down_3949 THBS1-down_7057|SOCS3-down_9021 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 THBS1-down_7057
hsa05160	hsa05323	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CLDN1-up MMP1-up|CLDN5-down CXCL12-up|CLDN5-down FLT1-down|CLDN5-down JUN-down|CLDN5-down MMP1-up|LDLR-down CTSK-up|SOCS3-down CTSK-up|JAK1-down CXCL12-up|LDLR-down CXCL12-up|SOCS3-down CXCL12-up|JAK1-down FLT1-down|LDLR-down FLT1-down|SOCS3-down FLT1-down|JAK1-down JUN-down|JAK1-down MMP1-up|LDLR-down JUN-down|SOCS3-down JUN-down|LDLR-down MMP1-up|SOCS3-down MMP1-up	CLDN1-up_9076 MMP1-up_4312|CLDN5-down_7122 CXCL12-up_6387|CLDN5-down_7122 FLT1-down_2321|CLDN5-down_7122 JUN-down_3725|CLDN5-down_7122 MMP1-up_4312|LDLR-down_3949 CTSK-up_1513|SOCS3-down_9021 CTSK-up_1513|JAK1-down_3716 CXCL12-up_6387|LDLR-down_3949 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|JAK1-down_3716 FLT1-down_2321|LDLR-down_3949 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP1-up_4312|LDLR-down_3949 JUN-down_3725|SOCS3-down_9021 JUN-down_3725|LDLR-down_3949 MMP1-up_4312|SOCS3-down_9021 MMP1-up_4312
hsa05160	hsa05412	Hepatitis C - Homo sapiens (human)	CLDN18,CLDN5,JAK1,LDLR,SOCS3,CLDN1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.002	CLDN1-up CDH2-up|CLDN5-down CDH2-up|JAK1-down CDH2-up|SOCS3-down CDH2-up|CLDN1-up ITGB4-up|CLDN1-up TCF7L2-up|CLDN5-down TCF7L2-up|LDLR-down TCF7L2-up	CLDN1-up_9076 CDH2-up_1000|CLDN5-down_7122 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|SOCS3-down_9021 CDH2-up_1000|CLDN1-up_9076 ITGB4-up_3691|CLDN1-up_9076 TCF7L2-up_6934|CLDN5-down_7122 TCF7L2-up_6934|LDLR-down_3949 TCF7L2-up_6934
hsa05164	hsa05202	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.004	JAK1-down CCND2-up|JUN-down CCND2-up|SOCS3-down CCND2-up|HSPA1A-down FLT1-down|HSPA1B-down FLT1-down|JAK1-down FLT1-down|JUN-down FLT1-down|SOCS3-down FLT1-down|HSPA1A-down IGF1-up|HSPA1B-down ZBTB16-down|JAK1-down IGF1-up|JUN-down IGF1-up|PRSS1-up IGF1-up|SOCS3-down IGF1-up|SOCS3-down IL1R2-down|JAK1-down PLAU-up|JAK1-down ZBTB16-down|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|SOCS3-down NFKBIZ-down|PRSS1-up PLAU-up|SOCS3-down PLAU-up|TMPRSS4-up PLAU-up	JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|HSPA1A-down_3303 FLT1-down_2321|HSPA1B-down_3304 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|HSPA1A-down_3303 IGF1-up_3479|HSPA1B-down_3304 ZBTB16-down_7704|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|SOCS3-down_9021 IL1R2-down_7850|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|SOCS3-down_9021 NFKBIZ-down_64332|PRSS1-up_5644 PLAU-up_5328|SOCS3-down_9021 PLAU-up_5328|TMPRSS4-up_56649 PLAU-up_5328
hsa05164	hsa05205	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.003	JUN-down CAV2-down|HSPA1A-down CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|JUN-down FLNC-up|JUN-down FZD5-down|JUN-down HBEGF-down|SOCS3-down HBEGF-down|HSPA1A-down IGF1-up|JAK1-down IGF1-up|JUN-down IGF1-up|PRSS1-up IGF1-up|SOCS3-down IGF1-up|JAK1-down MMP2-up|JAK1-down PLAU-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|SOCS3-down MMP2-up|TMPRSS4-up MMP2-up|PRSS1-up PLAU-up|SOCS3-down PLAU-up|TMPRSS4-up PLAU-up|SOCS3-down THBS1-down|TMPRSS4-up THBS1-down	JUN-down_3725 CAV2-down_858|HSPA1A-down_3303 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|JUN-down_3725 FLNC-up_2318|JUN-down_3725 FZD5-down_7855|JUN-down_3725 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|HSPA1A-down_3303 IGF1-up_3479|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|PRSS1-up_5644 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|SOCS3-down_9021 MMP2-up_4313|TMPRSS4-up_56649 MMP2-up_4313|PRSS1-up_5644 PLAU-up_5328|SOCS3-down_9021 PLAU-up_5328|TMPRSS4-up_56649 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057|TMPRSS4-up_56649 THBS1-down_7057
hsa05164	hsa05206	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	HSPA1A-down CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|JAK1-down CCND2-up|JUN-down CCND2-up|SOCS3-down CCND2-up|JUN-down CYP24A1-up|SOCS3-down CYP24A1-up|HSPA1A-down HMOX1-down|HSPA1B-down HMOX1-down|JAK1-down HMOX1-down|JUN-down HMOX1-down|SOCS3-down HMOX1-down|HSPA1A-down PDGFRA-down|HSPA1B-down PDGFRA-down|JAK1-down IRS2-down|JUN-down IRS2-down|SOCS3-down IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|SOCS3-down MCL1-down|SOCS3-down PDGFRA-down|PRSS1-up PLAU-up|SOCS3-down PLAU-up|TMPRSS4-up PLAU-up|PRSS1-up SERPINB5-up|SOCS3-down THBS1-down|SOCS3-down TNC-up|TMPRSS4-up THBS1-down	HSPA1A-down_3303 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|JUN-down_3725 CYP24A1-up_1591|SOCS3-down_9021 CYP24A1-up_1591|HSPA1A-down_3303 HMOX1-down_3162|HSPA1B-down_3304 HMOX1-down_3162|JAK1-down_3716 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|SOCS3-down_9021 HMOX1-down_3162|HSPA1A-down_3303 PDGFRA-down_5156|HSPA1B-down_3304 PDGFRA-down_5156|JAK1-down_3716 IRS2-down_8660|JUN-down_3725 IRS2-down_8660|SOCS3-down_9021 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|SOCS3-down_9021 MCL1-down_4170|SOCS3-down_9021 PDGFRA-down_5156|PRSS1-up_5644 PLAU-up_5328|SOCS3-down_9021 PLAU-up_5328|TMPRSS4-up_56649 PLAU-up_5328|PRSS1-up_5644 SERPINB5-up_5268|SOCS3-down_9021 THBS1-down_7057|SOCS3-down_9021 TNC-up_3371|TMPRSS4-up_56649 THBS1-down_7057
hsa05164	hsa05219	Influenza A - Homo sapiens (human)	HSPA1A,HSPA1B,JAK1,JUN,SOCS3,HLA-DOA,PRSS1,TMPRSS4	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.048	HSPA1A-down CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|JUN-down HBEGF-down|SOCS3-down HBEGF-down|JAK1-down MMP1-up|JAK1-down MMP2-up|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|PRSS1-up MMP1-up|SOCS3-down MMP1-up|SOCS3-down MMP2-up|TMPRSS4-up MMP2-up|SOCS3-down THBS1-down|TMPRSS4-up THBS1-down	HSPA1A-down_3303 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|JUN-down_3725 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|PRSS1-up_5644 MMP1-up_4312|SOCS3-down_9021 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|TMPRSS4-up_56649 MMP2-up_4313|SOCS3-down_9021 THBS1-down_7057|TMPRSS4-up_56649 THBS1-down_7057
hsa05166	hsa05202	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.001	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CCND1-up ZBTB16-down|CCND2-up FZD5-down|CCND2-up JAK1-down|CCND2-up JUN-down|CCND2-up PDGFRA-down|FZD5-down FLT1-down|JAK1-down FLT1-down|JUN-down FLT1-down|MYB-up FLT1-down|PDGFRA-down FLT1-down|TGFB3-up FLT1-down|VCAM1-up FLT1-down|FZD5-down PROM1-up|JAK1-down IGF1-up|JUN-down IGF1-up|MYB-up IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|VCAM1-up IGF1-up|JAK1-down PLAU-up|JAK1-down ZBTB16-down|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|MYB-up NFKBIZ-down|MYB-up PROM1-up|MYB-up SIX1-up|MYB-up ZBTB16-down|PDGFRA-down PLAU-up|PDGFRA-down PROM1-up|PDGFRA-down ZBTB16-down|TGFB3-up PLAU-up|VCAM1-up PLAU-up|VCAM1-up PROM1-up|TGFB3-up SIX1-up	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CCND1-up_595 ZBTB16-down_7704|CCND2-up_894 FZD5-down_7855|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|CCND2-up_894 PDGFRA-down_5156|FZD5-down_7855 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|MYB-up_4602 FLT1-down_2321|PDGFRA-down_5156 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|FZD5-down_7855 PROM1-up_8842|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MYB-up_4602 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|MYB-up_4602 NFKBIZ-down_64332|MYB-up_4602 PROM1-up_8842|MYB-up_4602 SIX1-up_6495|MYB-up_4602 ZBTB16-down_7704|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 PROM1-up_8842|PDGFRA-down_5156 ZBTB16-down_7704|TGFB3-up_7043 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|VCAM1-up_7412 PROM1-up_8842|TGFB3-up_7043 SIX1-up_6495
hsa05166	hsa05205	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.001	PDGFRA-down ANK2-up|JUN-down CAV2-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up PDGFRA-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|CCND2-up THBS1-down|JUN-down FLNC-up|MYB-up FLNC-up|VCAM1-up FLNC-up|IL1R2-down HBEGF-down|JUN-down HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|VCAM1-up HBEGF-down|JAK1-down IGF1-up|JUN-down IGF1-up|MYB-up IGF1-up|PDGFRA-down IGF1-up|TGFB3-up IGF1-up|VCAM1-up IGF1-up|JAK1-down MMP2-up|JAK1-down PLAU-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|MYB-up MMP2-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|VCAM1-up MMP2-up|MYB-up THBS1-down|PDGFRA-down PLAU-up|PDGFRA-down THBS1-down|TGFB3-up PLAU-up|VCAM1-up PLAU-up|TGFB3-up THBS1-down|VCAM1-up THBS1-down	PDGFRA-down_5156 ANK2-up_287|JUN-down_3725 CAV2-down_858|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 PDGFRA-down_5156|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|CCND2-up_894 THBS1-down_7057|JUN-down_3725 FLNC-up_2318|MYB-up_4602 FLNC-up_2318|VCAM1-up_7412 FLNC-up_2318|IL1R2-down_7850 HBEGF-down_1839|JUN-down_3725 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MYB-up_4602 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|TGFB3-up_7043 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|MYB-up_4602 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|MYB-up_4602 THBS1-down_7057|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa05166	hsa05206	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CCND1-up FZD5-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND2-up FZD5-down|CCND2-up JAK1-down|CCND2-up JUN-down|JUN-down CYP24A1-up|FZD5-down PDGFRA-down|JAK1-down HMOX1-down|JUN-down HMOX1-down|MYB-up HMOX1-down|VCAM1-up HMOX1-down|JAK1-down IRS2-down|JUN-down IRS2-down|MYB-up IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|MYB-up MCL1-down|VCAM1-up MCL1-down|MYB-up SERPINB5-up|MYB-up SOX4-up|MYB-up THBS1-down|MYB-up TNC-up|MYB-up TP63-up|TGFB3-up PLAU-up|VCAM1-up PLAU-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up|VCAM1-up THBS1-down|VCAM1-up TNC-up	CCND1-up_595 FZD5-down_7855|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND2-up_894 FZD5-down_7855|CCND2-up_894 JAK1-down_3716|CCND2-up_894 JUN-down_3725|JUN-down_3725 CYP24A1-up_1591|FZD5-down_7855 PDGFRA-down_5156|JAK1-down_3716 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|MYB-up_4602 HMOX1-down_3162|VCAM1-up_7412 HMOX1-down_3162|JAK1-down_3716 IRS2-down_8660|JUN-down_3725 IRS2-down_8660|MYB-up_4602 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|MYB-up_4602 MCL1-down_4170|VCAM1-up_7412 MCL1-down_4170|MYB-up_4602 SERPINB5-up_5268|MYB-up_4602 SOX4-up_6659|MYB-up_4602 THBS1-down_7057|MYB-up_4602 TNC-up_3371|MYB-up_4602 TP63-up_8626|TGFB3-up_7043 PLAU-up_5328|VCAM1-up_7412 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626|VCAM1-up_7412 THBS1-down_7057|VCAM1-up_7412 TNC-up_3371
hsa05166	hsa05219	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.001	CCND1-up FZD5-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up PDGFRA-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up THBS1-down|IL1R2-down HBEGF-down|JUN-down HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|VCAM1-up HBEGF-down|JAK1-down MMP1-up|JAK1-down MMP2-up|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|MYB-up MMP1-up|PDGFRA-down MMP1-up|TGFB3-up MMP1-up|VCAM1-up MMP1-up|MYB-up MMP2-up|PDGFRA-down MMP2-up|TGFB3-up MMP2-up|VCAM1-up MMP2-up|MYB-up THBS1-down|PDGFRA-down THBS1-down|TGFB3-up THBS1-down|VCAM1-up THBS1-down	CCND1-up_595 FZD5-down_7855|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 PDGFRA-down_5156|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 THBS1-down_7057|IL1R2-down_7850 HBEGF-down_1839|JUN-down_3725 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|VCAM1-up_7412 HBEGF-down_1839|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|MYB-up_4602 MMP1-up_4312|PDGFRA-down_5156 MMP1-up_4312|TGFB3-up_7043 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|MYB-up_4602 MMP2-up_4313|PDGFRA-down_5156 MMP2-up_4313|TGFB3-up_7043 MMP2-up_4313|VCAM1-up_7412 MMP2-up_4313|MYB-up_4602 THBS1-down_7057|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057|VCAM1-up_7412 THBS1-down_7057
hsa05166	hsa05323	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.005	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up FLT1-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|VCAM1-up CTSK-up|JAK1-down CXCL12-up|MYB-up CXCL12-up|PDGFRA-down CXCL12-up|VCAM1-up CXCL12-up|FZD5-down FLT1-down|JAK1-down FLT1-down|MYB-up FLT1-down|PDGFRA-down FLT1-down|VCAM1-up FLT1-down|FZD5-down JUN-down|JAK1-down JUN-down|JAK1-down MMP1-up|MYB-up MMP1-up|PDGFRA-down MMP1-up|VCAM1-up MMP1-up|PDGFRA-down TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FLT1-down_2321|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|VCAM1-up_7412 CTSK-up_1513|JAK1-down_3716 CXCL12-up_6387|MYB-up_4602 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|VCAM1-up_7412 CXCL12-up_6387|FZD5-down_7855 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|MYB-up_4602 FLT1-down_2321|PDGFRA-down_5156 FLT1-down_2321|VCAM1-up_7412 FLT1-down_2321|FZD5-down_7855 JUN-down_3725|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP1-up_4312|MYB-up_4602 MMP1-up_4312|PDGFRA-down_5156 MMP1-up_4312|VCAM1-up_7412 MMP1-up_4312|PDGFRA-down_5156 TGFB3-up_7043
hsa05166	hsa05410	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.039	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|FZD5-down ITGB8-up|JAK1-down IGF1-up|JUN-down IGF1-up|MYB-up IGF1-up|PDGFRA-down IGF1-up|VCAM1-up IGF1-up|JUN-down ITGB4-up|MYB-up ITGB4-up|PDGFRA-down ITGB4-up|VCAM1-up ITGB4-up|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|MYB-up TTN-down|PDGFRA-down TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|FZD5-down_7855 ITGB8-up_3696|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|MYB-up_4602 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|VCAM1-up_7412 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|MYB-up_4602 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MYB-up_4602 TTN-down_7273|PDGFRA-down_5156 TGFB3-up_7043
hsa05166	hsa05412	HTLV-I infection - Homo sapiens (human)	FZD5,IL1R2,JAK1,JUN,PDGFRA,CCND1,CCND2,HLA-DOA,MYB,TGFB3,VCAM1	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|FZD5-down CDH2-up|JAK1-down CDH2-up|JUN-down CDH2-up|MYB-up CDH2-up|PDGFRA-down CDH2-up|TGFB3-up CDH2-up|VCAM1-up CDH2-up|TGFB3-up DES-up|FZD5-down ITGB8-up|FZD5-down TCF7L2-up|JUN-down ITGB4-up|MYB-up ITGB4-up|PDGFRA-down ITGB4-up|VCAM1-up ITGB4-up|TGFB3-up ITGB8-up|JUN-down TCF7L2-up|MYB-up TCF7L2-up|PDGFRA-down TCF7L2-up|TGFB3-up TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|FZD5-down_7855 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|MYB-up_4602 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|VCAM1-up_7412 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 TCF7L2-up_6934|JUN-down_3725 ITGB4-up_3691|MYB-up_4602 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|VCAM1-up_7412 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 TCF7L2-up_6934|MYB-up_4602 TCF7L2-up_6934|PDGFRA-down_5156 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934
hsa05168	hsa05202	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0.002	JAK1-down CCND2-up|JUN-down CCND2-up|SOCS3-down CCND2-up|CD74-up IGF1-up|JAK1-down FLT1-down|JUN-down FLT1-down|SOCS3-down FLT1-down|JAK1-down IGF1-up|JUN-down IGF1-up|SOCS3-down IGF1-up|SOCS3-down IL1R2-down|JAK1-down PLAU-up|JAK1-down ZBTB16-down|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|SOCS3-down NFKBIZ-down|SOCS3-down PLAU-up	JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CD74-up_972 IGF1-up_3479|JAK1-down_3716 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|SOCS3-down_9021 IL1R2-down_7850|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|SOCS3-down_9021 NFKBIZ-down_64332|SOCS3-down_9021 PLAU-up_5328
hsa05168	hsa05205	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0	JUN-down CAV2-down|CD74-up CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|CD74-up IGF1-up|CD74-up MMP2-up|CD74-up THBS1-down|JUN-down FLNC-up|JUN-down FZD5-down|JUN-down HBEGF-down|SOCS3-down HBEGF-down|JAK1-down IGF1-up|JUN-down IGF1-up|SOCS3-down IGF1-up|JAK1-down MMP2-up|JAK1-down PLAU-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|SOCS3-down MMP2-up|SOCS3-down PLAU-up|SOCS3-down THBS1-down	JUN-down_3725 CAV2-down_858|CD74-up_972 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CD74-up_972 IGF1-up_3479|CD74-up_972 MMP2-up_4313|CD74-up_972 THBS1-down_7057|JUN-down_3725 FLNC-up_2318|JUN-down_3725 FZD5-down_7855|JUN-down_3725 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 IGF1-up_3479|JUN-down_3725 IGF1-up_3479|SOCS3-down_9021 IGF1-up_3479|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057
hsa05168	hsa05206	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CD74-up CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|JAK1-down CCND2-up|JUN-down CCND2-up|SOCS3-down CCND2-up|CD74-up HMOX1-down|CD74-up THBS1-down|CD74-up TP63-up|JUN-down CYP24A1-up|SOCS3-down CYP24A1-up|JAK1-down HMOX1-down|JUN-down HMOX1-down|SOCS3-down HMOX1-down|JAK1-down IRS2-down|JUN-down IRS2-down|SOCS3-down IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|SOCS3-down MCL1-down|SOCS3-down PDGFRA-down|SOCS3-down PLAU-up|SOCS3-down THBS1-down|SOCS3-down TNC-up	CD74-up_972 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|SOCS3-down_9021 CCND2-up_894|CD74-up_972 HMOX1-down_3162|CD74-up_972 THBS1-down_7057|CD74-up_972 TP63-up_8626|JUN-down_3725 CYP24A1-up_1591|SOCS3-down_9021 CYP24A1-up_1591|JAK1-down_3716 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|SOCS3-down_9021 HMOX1-down_3162|JAK1-down_3716 IRS2-down_8660|JUN-down_3725 IRS2-down_8660|SOCS3-down_9021 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|SOCS3-down_9021 MCL1-down_4170|SOCS3-down_9021 PDGFRA-down_5156|SOCS3-down_9021 PLAU-up_5328|SOCS3-down_9021 THBS1-down_7057|SOCS3-down_9021 TNC-up_3371
hsa05168	hsa05219	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.006	CD74-up CCND1-up|JAK1-down CCND1-up|JUN-down CCND1-up|SOCS3-down CCND1-up|CD74-up MMP2-up|CD74-up THBS1-down|JUN-down HBEGF-down|SOCS3-down HBEGF-down|JAK1-down MMP1-up|JAK1-down MMP2-up|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|SOCS3-down MMP1-up|SOCS3-down MMP2-up|SOCS3-down THBS1-down	CD74-up_972 CCND1-up_595|JAK1-down_3716 CCND1-up_595|JUN-down_3725 CCND1-up_595|SOCS3-down_9021 CCND1-up_595|CD74-up_972 MMP2-up_4313|CD74-up_972 THBS1-down_7057|JUN-down_3725 HBEGF-down_1839|SOCS3-down_9021 HBEGF-down_1839|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|SOCS3-down_9021 MMP1-up_4312|SOCS3-down_9021 MMP2-up_4313|SOCS3-down_9021 THBS1-down_7057
hsa05168	hsa05323	Herpes simplex infection - Homo sapiens (human)	JAK1,JUN,SOCS3,CD74,HLA-DOA	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.001	CD74-up CTSK-up|CD74-up CXCL12-up|SOCS3-down CTSK-up|JAK1-down CXCL12-up|SOCS3-down CXCL12-up|JAK1-down FLT1-down|SOCS3-down FLT1-down|JAK1-down JUN-down|JAK1-down MMP1-up|SOCS3-down MMP1-up	CD74-up_972 CTSK-up_1513|CD74-up_972 CXCL12-up_6387|SOCS3-down_9021 CTSK-up_1513|JAK1-down_3716 CXCL12-up_6387|SOCS3-down_9021 CXCL12-up_6387|JAK1-down_3716 FLT1-down_2321|SOCS3-down_9021 FLT1-down_2321|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP1-up_4312|SOCS3-down_9021 MMP1-up_4312
hsa05200	hsa05202	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	0	CCND1-up CCND2-up|CCND1-up FLT1-down|CCND1-up IGF1-up|CCND1-up NFKBIZ-down|CCND1-up PLAU-up|CCND1-up PROM1-up|CCND1-up SIX1-up|CCND1-up SIX4-up|CXCL12-up CCND2-up|FZD5-down CCND2-up|HHIP-down CCND2-up|JAK1-down CCND2-up|JUN-down CCND2-up|MMP1-up CCND2-up|MMP2-up CCND2-up|PDGFRA-down CCND2-up|TCF7L2-up CCND2-up|TGFB3-up CCND2-up|CXCL12-up FLT1-down|CXCL12-up IGF1-up|CXCL12-up PLAU-up|CXCL12-up PROM1-up|DAPK2-down ZBTB16-down|EDNRB-down FLT1-down|EDNRB-down IGF1-up|FGF14-up FLT1-down|FIGF-down FLT1-down|FIGF-down IGF1-up|FIGF-down PLAU-up|FIGF-down PROM1-up|FZD5-down FLT1-down|JAK1-down FLT1-down|JUN-down FLT1-down|MMP1-up FLT1-down|MMP2-up FLT1-down|PDGFRA-down FLT1-down|TGFB3-up FLT1-down|FZD5-down PROM1-up|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|JAK1-down PLAU-up|JAK1-down ZBTB16-down|JUN-down NFKBIZ-down|JUN-down PLAU-up|JUN-down PROM1-up|JUN-down SIX1-up|JUN-down ZBTB16-down|LAMA3-down PLAU-up|MMP1-up PLAU-up|MMP1-up PROM1-up|MMP2-up PLAU-up|MMP2-up PROM1-up|PDGFRA-down PLAU-up|PDGFRA-down PROM1-up|PDGFRA-down ZBTB16-down|TGFB3-up PLAU-up|TGFB3-up SIX1-up	CCND1-up_595 CCND2-up_894|CCND1-up_595 FLT1-down_2321|CCND1-up_595 IGF1-up_3479|CCND1-up_595 NFKBIZ-down_64332|CCND1-up_595 PLAU-up_5328|CCND1-up_595 PROM1-up_8842|CCND1-up_595 SIX1-up_6495|CCND1-up_595 SIX4-up_51804|CXCL12-up_6387 CCND2-up_894|FZD5-down_7855 CCND2-up_894|HHIP-down_64399 CCND2-up_894|JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|MMP1-up_4312 CCND2-up_894|MMP2-up_4313 CCND2-up_894|PDGFRA-down_5156 CCND2-up_894|TCF7L2-up_6934 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|CXCL12-up_6387 FLT1-down_2321|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 PROM1-up_8842|DAPK2-down_23604 ZBTB16-down_7704|EDNRB-down_1910 FLT1-down_2321|EDNRB-down_1910 IGF1-up_3479|FGF14-up_2259 FLT1-down_2321|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 PROM1-up_8842|FZD5-down_7855 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|JUN-down_3725 FLT1-down_2321|MMP1-up_4312 FLT1-down_2321|MMP2-up_4313 FLT1-down_2321|PDGFRA-down_5156 FLT1-down_2321|TGFB3-up_7043 FLT1-down_2321|FZD5-down_7855 PROM1-up_8842|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|JAK1-down_3716 ZBTB16-down_7704|JUN-down_3725 NFKBIZ-down_64332|JUN-down_3725 PLAU-up_5328|JUN-down_3725 PROM1-up_8842|JUN-down_3725 SIX1-up_6495|JUN-down_3725 ZBTB16-down_7704|LAMA3-down_3909 PLAU-up_5328|MMP1-up_4312 PLAU-up_5328|MMP1-up_4312 PROM1-up_8842|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 PROM1-up_8842|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 PROM1-up_8842|PDGFRA-down_5156 ZBTB16-down_7704|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 SIX1-up_6495
hsa05200	hsa05205	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.003	PDGFRA-down ANK2-up|TCF7L2-up ANK2-up|ZBTB16-down ANK2-up|JUN-down CAV2-down|LAMA3-down CAV2-down|CCND1-up CSF3R-down|CCND1-up EDNRB-down|CCND1-up FIGF-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up LAMA3-down|CCND1-up PDGFRA-down|CCND1-up ZBTB16-down|CXCL12-up HBEGF-down|CXCL12-up IGF1-up|CXCL12-up MMP2-up|CXCL12-up PLAU-up|CXCL12-up THBS1-down|EDNRB-down HBEGF-down|EDNRB-down IGF1-up|EDNRB-down MMP2-up|EDNRB-down THBS1-down|FIGF-down HBEGF-down|FIGF-down IGF1-up|FIGF-down MMP2-up|FIGF-down PLAU-up|FIGF-down THBS1-down|JUN-down FLNC-up|JUN-down HBEGF-down|LAMA3-down HBEGF-down|MMP1-up HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|ZBTB16-down HBEGF-down|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|IGF1-up ZBTB16-down|JAK1-down MMP2-up|JAK1-down PLAU-up|JUN-down MMP2-up|JUN-down PLAU-up|JUN-down THBS1-down|LAMA3-down MMP2-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|MMP1-up MMP2-up|MMP1-up PLAU-up|MMP1-up THBS1-down|MMP2-up PDGFRA-down|PDGFRA-down PLAU-up|PDGFRA-down THBS1-down|TGFB3-up PLAU-up|TGFB3-up THBS1-down|ZBTB16-down THBS1-down	PDGFRA-down_5156 ANK2-up_287|TCF7L2-up_6934 ANK2-up_287|ZBTB16-down_7704 ANK2-up_287|JUN-down_3725 CAV2-down_858|LAMA3-down_3909 CAV2-down_858|CCND1-up_595 CSF3R-down_1441|CCND1-up_595 EDNRB-down_1910|CCND1-up_595 FIGF-down_2277|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 PDGFRA-down_5156|CCND1-up_595 ZBTB16-down_7704|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 THBS1-down_7057|EDNRB-down_1910 HBEGF-down_1839|EDNRB-down_1910 IGF1-up_3479|EDNRB-down_1910 MMP2-up_4313|EDNRB-down_1910 THBS1-down_7057|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|JUN-down_3725 FLNC-up_2318|JUN-down_3725 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|MMP1-up_4312 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|ZBTB16-down_7704 HBEGF-down_1839|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 ZBTB16-down_7704|JAK1-down_3716 MMP2-up_4313|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MMP2-up_4313|JUN-down_3725 PLAU-up_5328|JUN-down_3725 THBS1-down_7057|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|MMP1-up_4312 MMP2-up_4313|MMP1-up_4312 PLAU-up_5328|MMP1-up_4312 THBS1-down_7057|MMP2-up_4313 PDGFRA-down_5156|PDGFRA-down_5156 PLAU-up_5328|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 PLAU-up_5328|TGFB3-up_7043 THBS1-down_7057|ZBTB16-down_7704 THBS1-down_7057
hsa05200	hsa05206	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0	CCND1-up CSF3R-down|CCND1-up EDNRB-down|CCND1-up FIGF-down|CCND1-up FZD5-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up LAMA3-down|CCND1-up ZBTB16-down|CXCL12-up CCND2-up|FZD5-down CCND2-up|HHIP-down CCND2-up|IGF1-up CCND2-up|JAK1-down CCND2-up|JUN-down CCND2-up|MMP1-up CCND2-up|MMP2-up CCND2-up|TCF7L2-up CCND2-up|TGFB3-up CCND2-up|ZBTB16-down CCND2-up|CXCL12-up HMOX1-down|CXCL12-up MCL1-down|CXCL12-up MMP16-up|CXCL12-up PLAU-up|CXCL12-up SERPINB5-up|CXCL12-up SOX4-up|CXCL12-up THBS1-down|CXCL12-up TNC-up|IGF1-up CYP24A1-up|JUN-down CYP24A1-up|EDNRB-down HMOX1-down|EDNRB-down MCL1-down|EDNRB-down THBS1-down|EDNRB-down TNC-up|FIGF-down HMOX1-down|FIGF-down PDGFRA-down|FIGF-down PLAU-up|FIGF-down THBS1-down|FIGF-down TNC-up|FZD5-down PDGFRA-down|HHIP-down PDGFRA-down|IGF1-up HMOX1-down|JAK1-down HMOX1-down|JUN-down HMOX1-down|MMP1-up HMOX1-down|MMP2-up HMOX1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up THBS1-down|IGF1-up TNC-up|JAK1-down IRS2-down|JUN-down IRS2-down|TCF7L2-up IRS2-down|JAK1-down MCL1-down|JAK1-down PDGFRA-down|JAK1-down PLAU-up|JUN-down MCL1-down|JUN-down MMP16-up|JUN-down PDGFRA-down|JUN-down PLAU-up|JUN-down SERPINB5-up|JUN-down SOX4-up|JUN-down THBS1-down|JUN-down TNC-up|JUN-down TP63-up|LAMA3-down PLAU-up|LAMA3-down THBS1-down|LAMA3-down TNC-up|MMP1-up MCL1-down|MMP2-up MCL1-down|ZBTB16-down MCL1-down|MMP2-up MMP16-up|MMP1-up PLAU-up|MMP1-up SERPINB5-up|MMP1-up THBS1-down|MMP1-up TNC-up|MMP2-up PLAU-up|MMP2-up SERPINB5-up|MMP2-up SOX4-up|MMP2-up THBS1-down|MMP2-up TNC-up|TGFB3-up PLAU-up|TCF7L2-up TP63-up|TGFB3-up THBS1-down|TGFB3-up TNC-up|TGFB3-up TP63-up|ZBTB16-down THBS1-down|ZBTB16-down TP63-up	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 EDNRB-down_1910|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FZD5-down_7855|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 ZBTB16-down_7704|CXCL12-up_6387 CCND2-up_894|FZD5-down_7855 CCND2-up_894|HHIP-down_64399 CCND2-up_894|IGF1-up_3479 CCND2-up_894|JAK1-down_3716 CCND2-up_894|JUN-down_3725 CCND2-up_894|MMP1-up_4312 CCND2-up_894|MMP2-up_4313 CCND2-up_894|TCF7L2-up_6934 CCND2-up_894|TGFB3-up_7043 CCND2-up_894|ZBTB16-down_7704 CCND2-up_894|CXCL12-up_6387 HMOX1-down_3162|CXCL12-up_6387 MCL1-down_4170|CXCL12-up_6387 MMP16-up_4325|CXCL12-up_6387 PLAU-up_5328|CXCL12-up_6387 SERPINB5-up_5268|CXCL12-up_6387 SOX4-up_6659|CXCL12-up_6387 THBS1-down_7057|CXCL12-up_6387 TNC-up_3371|IGF1-up_3479 CYP24A1-up_1591|JUN-down_3725 CYP24A1-up_1591|EDNRB-down_1910 HMOX1-down_3162|EDNRB-down_1910 MCL1-down_4170|EDNRB-down_1910 THBS1-down_7057|EDNRB-down_1910 TNC-up_3371|FIGF-down_2277 HMOX1-down_3162|FIGF-down_2277 PDGFRA-down_5156|FIGF-down_2277 PLAU-up_5328|FIGF-down_2277 THBS1-down_7057|FIGF-down_2277 TNC-up_3371|FZD5-down_7855 PDGFRA-down_5156|HHIP-down_64399 PDGFRA-down_5156|IGF1-up_3479 HMOX1-down_3162|JAK1-down_3716 HMOX1-down_3162|JUN-down_3725 HMOX1-down_3162|MMP1-up_4312 HMOX1-down_3162|MMP2-up_4313 HMOX1-down_3162|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 TNC-up_3371|JAK1-down_3716 IRS2-down_8660|JUN-down_3725 IRS2-down_8660|TCF7L2-up_6934 IRS2-down_8660|JAK1-down_3716 MCL1-down_4170|JAK1-down_3716 PDGFRA-down_5156|JAK1-down_3716 PLAU-up_5328|JUN-down_3725 MCL1-down_4170|JUN-down_3725 MMP16-up_4325|JUN-down_3725 PDGFRA-down_5156|JUN-down_3725 PLAU-up_5328|JUN-down_3725 SERPINB5-up_5268|JUN-down_3725 SOX4-up_6659|JUN-down_3725 THBS1-down_7057|JUN-down_3725 TNC-up_3371|JUN-down_3725 TP63-up_8626|LAMA3-down_3909 PLAU-up_5328|LAMA3-down_3909 THBS1-down_7057|LAMA3-down_3909 TNC-up_3371|MMP1-up_4312 MCL1-down_4170|MMP2-up_4313 MCL1-down_4170|ZBTB16-down_7704 MCL1-down_4170|MMP2-up_4313 MMP16-up_4325|MMP1-up_4312 PLAU-up_5328|MMP1-up_4312 SERPINB5-up_5268|MMP1-up_4312 THBS1-down_7057|MMP1-up_4312 TNC-up_3371|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 SERPINB5-up_5268|MMP2-up_4313 SOX4-up_6659|MMP2-up_4313 THBS1-down_7057|MMP2-up_4313 TNC-up_3371|TGFB3-up_7043 PLAU-up_5328|TCF7L2-up_6934 TP63-up_8626|TGFB3-up_7043 THBS1-down_7057|TGFB3-up_7043 TNC-up_3371|TGFB3-up_7043 TP63-up_8626|ZBTB16-down_7704 THBS1-down_7057|ZBTB16-down_7704 TP63-up_8626
hsa05200	hsa05219	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0.001	CCND1-up CSF3R-down|CCND1-up EDNRB-down|CCND1-up FIGF-down|CCND1-up FZD5-down|CCND1-up JAK1-down|CCND1-up JUN-down|CCND1-up LAMA3-down|CCND1-up PDGFRA-down|CCND1-up ZBTB16-down|CXCL12-up HBEGF-down|CXCL12-up MMP1-up|CXCL12-up MMP2-up|CXCL12-up THBS1-down|EDNRB-down HBEGF-down|EDNRB-down MMP1-up|EDNRB-down MMP2-up|EDNRB-down THBS1-down|FIGF-down HBEGF-down|FIGF-down MMP1-up|FIGF-down MMP2-up|FIGF-down THBS1-down|IGF1-up HBEGF-down|JUN-down HBEGF-down|LAMA3-down HBEGF-down|PDGFRA-down HBEGF-down|TGFB3-up HBEGF-down|ZBTB16-down HBEGF-down|IGF1-up MMP1-up|IGF1-up MMP2-up|IGF1-up THBS1-down|JAK1-down MMP1-up|JAK1-down MMP2-up|JUN-down MMP1-up|JUN-down MMP2-up|JUN-down THBS1-down|LAMA3-down MMP1-up|LAMA3-down MMP2-up|LAMA3-down THBS1-down|MMP1-up PDGFRA-down|MMP2-up PDGFRA-down|PDGFRA-down THBS1-down|TGFB3-up THBS1-down|ZBTB16-down THBS1-down	CCND1-up_595 CSF3R-down_1441|CCND1-up_595 EDNRB-down_1910|CCND1-up_595 FIGF-down_2277|CCND1-up_595 FZD5-down_7855|CCND1-up_595 JAK1-down_3716|CCND1-up_595 JUN-down_3725|CCND1-up_595 LAMA3-down_3909|CCND1-up_595 PDGFRA-down_5156|CCND1-up_595 ZBTB16-down_7704|CXCL12-up_6387 HBEGF-down_1839|CXCL12-up_6387 MMP1-up_4312|CXCL12-up_6387 MMP2-up_4313|CXCL12-up_6387 THBS1-down_7057|EDNRB-down_1910 HBEGF-down_1839|EDNRB-down_1910 MMP1-up_4312|EDNRB-down_1910 MMP2-up_4313|EDNRB-down_1910 THBS1-down_7057|FIGF-down_2277 HBEGF-down_1839|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 MMP2-up_4313|FIGF-down_2277 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|JUN-down_3725 HBEGF-down_1839|LAMA3-down_3909 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|TGFB3-up_7043 HBEGF-down_1839|ZBTB16-down_7704 HBEGF-down_1839|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THBS1-down_7057|JAK1-down_3716 MMP1-up_4312|JAK1-down_3716 MMP2-up_4313|JUN-down_3725 MMP1-up_4312|JUN-down_3725 MMP2-up_4313|JUN-down_3725 THBS1-down_7057|LAMA3-down_3909 MMP1-up_4312|LAMA3-down_3909 MMP2-up_4313|LAMA3-down_3909 THBS1-down_7057|MMP1-up_4312 PDGFRA-down_5156|MMP2-up_4313 PDGFRA-down_5156|PDGFRA-down_5156 THBS1-down_7057|TGFB3-up_7043 THBS1-down_7057|ZBTB16-down_7704 THBS1-down_7057
hsa05200	hsa05323	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CSF3R-down CXCL12-up|CSF3R-down JUN-down|EDNRB-down CTSK-up|IGF1-up CTSK-up|MMP2-up CTSK-up|CXCL12-up EDNRB-down|CXCL12-up FIGF-down|CXCL12-up JAK1-down|CXCL12-up PDGFRA-down|CXCL12-up ZBTB16-down|EDNRB-down FLT1-down|EDNRB-down JUN-down|EDNRB-down MMP1-up|FGF14-up FLT1-down|FGF14-up TGFB3-up|FIGF-down FLT1-down|FIGF-down JUN-down|FIGF-down MMP1-up|FIGF-down TGFB3-up|FZD5-down FLT1-down|IGF1-up FLT1-down|JAK1-down FLT1-down|MMP2-up FLT1-down|PDGFRA-down FLT1-down|ZBTB16-down FLT1-down|FZD5-down JUN-down|HHIP-down JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|JAK1-down JUN-down|JAK1-down MMP1-up|LAMA3-down MMP1-up|MMP1-up PDGFRA-down|MMP2-up TGFB3-up|PDGFRA-down TGFB3-up|TCF7L2-up TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CSF3R-down_1441 CXCL12-up_6387|CSF3R-down_1441 JUN-down_3725|EDNRB-down_1910 CTSK-up_1513|IGF1-up_3479 CTSK-up_1513|MMP2-up_4313 CTSK-up_1513|CXCL12-up_6387 EDNRB-down_1910|CXCL12-up_6387 FIGF-down_2277|CXCL12-up_6387 JAK1-down_3716|CXCL12-up_6387 PDGFRA-down_5156|CXCL12-up_6387 ZBTB16-down_7704|EDNRB-down_1910 FLT1-down_2321|EDNRB-down_1910 JUN-down_3725|EDNRB-down_1910 MMP1-up_4312|FGF14-up_2259 FLT1-down_2321|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 FLT1-down_2321|FIGF-down_2277 JUN-down_3725|FIGF-down_2277 MMP1-up_4312|FIGF-down_2277 TGFB3-up_7043|FZD5-down_7855 FLT1-down_2321|IGF1-up_3479 FLT1-down_2321|JAK1-down_3716 FLT1-down_2321|MMP2-up_4313 FLT1-down_2321|PDGFRA-down_5156 FLT1-down_2321|ZBTB16-down_7704 FLT1-down_2321|FZD5-down_7855 JUN-down_3725|HHIP-down_64399 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|JAK1-down_3716 JUN-down_3725|JAK1-down_3716 MMP1-up_4312|LAMA3-down_3909 MMP1-up_4312|MMP1-up_4312 PDGFRA-down_5156|MMP2-up_4313 TGFB3-up_7043|PDGFRA-down_5156 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043
hsa05200	hsa05410	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.002	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|DAPK2-down PRKAA2-up|DAPK2-down TNNC1-down|EDNRB-down IGF1-up|FGF14-up TGFB3-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FZD5-down ITGB8-up|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|IGF1-up ZBTB16-down|LAMA3-down ITGA10-down|JUN-down ITGB4-up|LAMA3-down ITGB4-up|MMP1-up ITGB4-up|MMP2-up ITGB4-up|PDGFRA-down ITGB4-up|LAMA3-down ITGB8-up|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|MMP1-up TGFB3-up|MMP2-up TGFB3-up|MMP2-up TTN-down|PDGFRA-down TGFB3-up|TCF7L2-up TGFB3-up|ZBTB16-down TNNC1-down	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|DAPK2-down_23604 PRKAA2-up_5563|DAPK2-down_23604 TNNC1-down_7134|EDNRB-down_1910 IGF1-up_3479|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FZD5-down_7855 ITGB8-up_3696|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 ZBTB16-down_7704|LAMA3-down_3909 ITGA10-down_8515|JUN-down_3725 ITGB4-up_3691|LAMA3-down_3909 ITGB4-up_3691|MMP1-up_4312 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|LAMA3-down_3909 ITGB8-up_3696|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MMP1-up_4312 TGFB3-up_7043|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|PDGFRA-down_5156 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043|ZBTB16-down_7704 TNNC1-down_7134
hsa05200	hsa05412	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CXCL12-up CDH2-up|EDNRB-down CDH2-up|FIGF-down CDH2-up|FZD5-down CDH2-up|IGF1-up CDH2-up|JAK1-down CDH2-up|JUN-down CDH2-up|MMP1-up CDH2-up|MMP2-up CDH2-up|PDGFRA-down CDH2-up|TGFB3-up CDH2-up|TGFB3-up DES-up|FGF14-up TCF7L2-up|FZD5-down ITGB8-up|FZD5-down TCF7L2-up|HHIP-down TCF7L2-up|IGF1-up TCF7L2-up|LAMA3-down ITGA10-down|JUN-down ITGB4-up|LAMA3-down ITGB4-up|MMP1-up ITGB4-up|MMP2-up ITGB4-up|PDGFRA-down ITGB4-up|LAMA3-down ITGB8-up|TGFB3-up ITGB8-up|JUN-down TCF7L2-up|MMP2-up TCF7L2-up|PDGFRA-down TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CXCL12-up_6387 CDH2-up_1000|EDNRB-down_1910 CDH2-up_1000|FIGF-down_2277 CDH2-up_1000|FZD5-down_7855 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|JAK1-down_3716 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|MMP1-up_4312 CDH2-up_1000|MMP2-up_4313 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|FGF14-up_2259 TCF7L2-up_6934|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 TCF7L2-up_6934|HHIP-down_64399 TCF7L2-up_6934|IGF1-up_3479 TCF7L2-up_6934|LAMA3-down_3909 ITGA10-down_8515|JUN-down_3725 ITGB4-up_3691|LAMA3-down_3909 ITGB4-up_3691|MMP1-up_4312 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|LAMA3-down_3909 ITGB8-up_3696|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 TCF7L2-up_6934|MMP2-up_4313 TCF7L2-up_6934|PDGFRA-down_5156 TCF7L2-up_6934
hsa05200	hsa05414	Pathways in cancer - Homo sapiens (human)	CSF3R,DAPK2,EDNRB,FIGF,FZD5,HHIP,JAK1,JUN,LAMA3,PDGFRA,ZBTB16,CCND1,CXCL12,FGF14,IGF1,MMP1,MMP2,TCF7L2,TGFB3	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.023	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|DAPK2-down TNNC1-down|EDNRB-down IGF1-up|EDNRB-down PLN-up|FGF14-up TGFB3-up|FIGF-down IGF1-up|FIGF-down TGFB3-up|FZD5-down ITGB8-up|IGF1-up JAK1-down|IGF1-up JUN-down|IGF1-up PDGFRA-down|IGF1-up ZBTB16-down|LAMA3-down ITGA10-down|JUN-down ITGB4-up|LAMA3-down ITGB4-up|MMP1-up ITGB4-up|MMP2-up ITGB4-up|PDGFRA-down ITGB4-up|LAMA3-down ITGB8-up|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down|MMP1-up TGFB3-up|MMP2-up PLN-up|MMP2-up TGFB3-up|MMP2-up TTN-down|PDGFRA-down TGFB3-up|TCF7L2-up TGFB3-up|ZBTB16-down TNNC1-down	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|DAPK2-down_23604 TNNC1-down_7134|EDNRB-down_1910 IGF1-up_3479|EDNRB-down_1910 PLN-up_5350|FGF14-up_2259 TGFB3-up_7043|FIGF-down_2277 IGF1-up_3479|FIGF-down_2277 TGFB3-up_7043|FZD5-down_7855 ITGB8-up_3696|IGF1-up_3479 JAK1-down_3716|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 ZBTB16-down_7704|LAMA3-down_3909 ITGA10-down_8515|JUN-down_3725 ITGB4-up_3691|LAMA3-down_3909 ITGB4-up_3691|MMP1-up_4312 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|LAMA3-down_3909 ITGB8-up_3696|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MMP1-up_4312 TGFB3-up_7043|MMP2-up_4313 PLN-up_5350|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|PDGFRA-down_5156 TGFB3-up_7043|TCF7L2-up_6934 TGFB3-up_7043|ZBTB16-down_7704 TNNC1-down_7134
hsa05202	hsa05205	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	0.012	FLT1-down ANK2-up|ZBTB16-down ANK2-up|SIX1-up CAV2-down|CCND2-up CCND1-up|FLT1-down CCND1-up|NFKBIZ-down CCND1-up|PROM1-up CCND1-up|SIX1-up CCND1-up|SIX4-up CCND1-up|ZBTB16-down CCND1-up|CCND2-up FZD5-down|CCND2-up HBEGF-down|CCND2-up IGF1-up|CCND2-up MMP2-up|CCND2-up PLAU-up|CCND2-up THBS1-down|FLT1-down FZD5-down|FLT1-down HBEGF-down|FLT1-down IGF1-up|FLT1-down MMP2-up|FLT1-down PLAU-up|FLT1-down THBS1-down|PROM1-up FZD5-down|IL1R2-down HBEGF-down|PROM1-up HBEGF-down|ZBTB16-down HBEGF-down|IGF1-up ZBTB16-down|PROM1-up MMP2-up|PROM1-up THBS1-down|ZBTB16-down THBS1-down	FLT1-down_2321 ANK2-up_287|ZBTB16-down_7704 ANK2-up_287|SIX1-up_6495 CAV2-down_858|CCND2-up_894 CCND1-up_595|FLT1-down_2321 CCND1-up_595|NFKBIZ-down_64332 CCND1-up_595|PROM1-up_8842 CCND1-up_595|SIX1-up_6495 CCND1-up_595|SIX4-up_51804 CCND1-up_595|ZBTB16-down_7704 CCND1-up_595|CCND2-up_894 FZD5-down_7855|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 IGF1-up_3479|CCND2-up_894 MMP2-up_4313|CCND2-up_894 PLAU-up_5328|CCND2-up_894 THBS1-down_7057|FLT1-down_2321 FZD5-down_7855|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 THBS1-down_7057|PROM1-up_8842 FZD5-down_7855|IL1R2-down_7850 HBEGF-down_1839|PROM1-up_8842 HBEGF-down_1839|ZBTB16-down_7704 HBEGF-down_1839|IGF1-up_3479 ZBTB16-down_7704|PROM1-up_8842 MMP2-up_4313|PROM1-up_8842 THBS1-down_7057|ZBTB16-down_7704 THBS1-down_7057
hsa05202	hsa05206	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.014	FLT1-down CCND1-up|IGF1-up CCND1-up|NFKBIZ-down CCND1-up|PROM1-up CCND1-up|SIX1-up CCND1-up|SIX4-up CCND1-up|ZBTB16-down CCND1-up|CCND2-up FLT1-down|CCND2-up ZBTB16-down|IGF1-up CYP24A1-up|FLT1-down HMOX1-down|FLT1-down IRS2-down|FLT1-down MCL1-down|FLT1-down MMP16-up|FLT1-down PDGFRA-down|FLT1-down PLAU-up|FLT1-down SERPINB5-up|FLT1-down THBS1-down|FLT1-down TNC-up|FLT1-down TP63-up|IGF1-up HMOX1-down|PROM1-up HMOX1-down|SIX1-up HMOX1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up THBS1-down|IGF1-up TNC-up|SIX1-up IRS2-down|NFKBIZ-down MCL1-down|PROM1-up MCL1-down|ZBTB16-down MCL1-down|PROM1-up PDGFRA-down|ZBTB16-down PDGFRA-down|PROM1-up SOX4-up|PROM1-up THBS1-down|PROM1-up TNC-up|ZBTB16-down THBS1-down|ZBTB16-down TP63-up	FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|NFKBIZ-down_64332 CCND1-up_595|PROM1-up_8842 CCND1-up_595|SIX1-up_6495 CCND1-up_595|SIX4-up_51804 CCND1-up_595|ZBTB16-down_7704 CCND1-up_595|CCND2-up_894 FLT1-down_2321|CCND2-up_894 ZBTB16-down_7704|IGF1-up_3479 CYP24A1-up_1591|FLT1-down_2321 HMOX1-down_3162|FLT1-down_2321 IRS2-down_8660|FLT1-down_2321 MCL1-down_4170|FLT1-down_2321 MMP16-up_4325|FLT1-down_2321 PDGFRA-down_5156|FLT1-down_2321 PLAU-up_5328|FLT1-down_2321 SERPINB5-up_5268|FLT1-down_2321 THBS1-down_7057|FLT1-down_2321 TNC-up_3371|FLT1-down_2321 TP63-up_8626|IGF1-up_3479 HMOX1-down_3162|PROM1-up_8842 HMOX1-down_3162|SIX1-up_6495 HMOX1-down_3162|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 THBS1-down_7057|IGF1-up_3479 TNC-up_3371|SIX1-up_6495 IRS2-down_8660|NFKBIZ-down_64332 MCL1-down_4170|PROM1-up_8842 MCL1-down_4170|ZBTB16-down_7704 MCL1-down_4170|PROM1-up_8842 PDGFRA-down_5156|ZBTB16-down_7704 PDGFRA-down_5156|PROM1-up_8842 SOX4-up_6659|PROM1-up_8842 THBS1-down_7057|PROM1-up_8842 TNC-up_3371|ZBTB16-down_7704 THBS1-down_7057|ZBTB16-down_7704 TP63-up_8626
hsa05202	hsa05219	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCND2-up CCND1-up|FLT1-down CCND1-up|IGF1-up CCND1-up|NFKBIZ-down CCND1-up|PLAU-up CCND1-up|PROM1-up CCND1-up|SIX1-up CCND1-up|SIX4-up CCND1-up|ZBTB16-down CCND1-up|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|CCND2-up THBS1-down|ZBTB16-down DAPK2-down|FLT1-down HBEGF-down|FLT1-down MMP1-up|FLT1-down MMP2-up|FLT1-down THBS1-down|IGF1-up HBEGF-down|IL1R2-down HBEGF-down|PLAU-up HBEGF-down|PROM1-up HBEGF-down|ZBTB16-down HBEGF-down|IGF1-up MMP1-up|IGF1-up MMP2-up|IGF1-up THBS1-down|PLAU-up MMP1-up|PROM1-up MMP1-up|PLAU-up MMP2-up|PROM1-up MMP2-up|PLAU-up THBS1-down|PROM1-up THBS1-down|ZBTB16-down THBS1-down	CCND2-up_894 CCND1-up_595|FLT1-down_2321 CCND1-up_595|IGF1-up_3479 CCND1-up_595|NFKBIZ-down_64332 CCND1-up_595|PLAU-up_5328 CCND1-up_595|PROM1-up_8842 CCND1-up_595|SIX1-up_6495 CCND1-up_595|SIX4-up_51804 CCND1-up_595|ZBTB16-down_7704 CCND1-up_595|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|CCND2-up_894 THBS1-down_7057|ZBTB16-down_7704 DAPK2-down_23604|FLT1-down_2321 HBEGF-down_1839|FLT1-down_2321 MMP1-up_4312|FLT1-down_2321 MMP2-up_4313|FLT1-down_2321 THBS1-down_7057|IGF1-up_3479 HBEGF-down_1839|IL1R2-down_7850 HBEGF-down_1839|PLAU-up_5328 HBEGF-down_1839|PROM1-up_8842 HBEGF-down_1839|ZBTB16-down_7704 HBEGF-down_1839|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 MMP2-up_4313|IGF1-up_3479 THBS1-down_7057|PLAU-up_5328 MMP1-up_4312|PROM1-up_8842 MMP1-up_4312|PLAU-up_5328 MMP2-up_4313|PROM1-up_8842 MMP2-up_4313|PLAU-up_5328 THBS1-down_7057|PROM1-up_8842 THBS1-down_7057|ZBTB16-down_7704 THBS1-down_7057
hsa05202	hsa05410	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.041	CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|IGF1-up ZBTB16-down|PLAU-up ITGB4-up|PROM1-up ITGB4-up|PLAU-up TGFB3-up|SIX1-up TGFB3-up|SIX1-up TTN-down|ZBTB16-down TNNC1-down	CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|IGF1-up_3479 ZBTB16-down_7704|PLAU-up_5328 ITGB4-up_3691|PROM1-up_8842 ITGB4-up_3691|PLAU-up_5328 TGFB3-up_7043|SIX1-up_6495 TGFB3-up_7043|SIX1-up_6495 TTN-down_7273|ZBTB16-down_7704 TNNC1-down_7134
hsa05202	hsa05412	Transcriptional misregulation in cancer - Homo sapiens (human)	DEFA3,FLT1,IL1R2,NFKBIZ,ZBTB16,CCND2,IGF1,PLAU,PROM1,SIX1,SIX4	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.005	CCND2-up CDH2-up|CCND2-up TCF7L2-up|FLT1-down CDH2-up|IGF1-up CDH2-up|PLAU-up CDH2-up|PROM1-up CDH2-up|SIX1-up CDH2-up|FLT1-down ITGB4-up|IGF1-up TCF7L2-up|PLAU-up ITGB4-up|PROM1-up ITGB4-up	CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|FLT1-down_2321 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|PLAU-up_5328 CDH2-up_1000|PROM1-up_8842 CDH2-up_1000|SIX1-up_6495 CDH2-up_1000|FLT1-down_2321 ITGB4-up_3691|IGF1-up_3479 TCF7L2-up_6934|PLAU-up_5328 ITGB4-up_3691|PROM1-up_8842 ITGB4-up_3691
hsa05205	hsa05206	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	0.005	ANK2-up PDGFRA-down|CAV2-down CCND1-up|CAV2-down HMOX1-down|CAV2-down SERPINB5-up|CCND1-up FZD5-down|CCND1-up HBEGF-down|FZD5-down CCND2-up|HBEGF-down CCND2-up|IGF1-up CCND2-up|MMP2-up CCND2-up|IGF1-up CYP24A1-up|FLNC-up MMP16-up|FLNC-up TNC-up|FLNC-up TP63-up|FZD5-down PDGFRA-down|HBEGF-down HMOX1-down|HBEGF-down MCL1-down|HBEGF-down MMP16-up|HBEGF-down PDGFRA-down|HBEGF-down PLAU-up|HBEGF-down THBS1-down|HBEGF-down TNC-up|IGF1-up HMOX1-down|MMP2-up HMOX1-down|IGF1-up IRS2-down|IGF1-up MCL1-down|IGF1-up PDGFRA-down|IGF1-up TNC-up|MMP2-up MCL1-down|MMP2-up MMP16-up|MMP2-up PDGFRA-down|MMP2-up PLAU-up|MMP2-up SERPINB5-up|MMP2-up SOX4-up|MMP2-up TNC-up	ANK2-up_287 PDGFRA-down_5156|CAV2-down_858 CCND1-up_595|CAV2-down_858 HMOX1-down_3162|CAV2-down_858 SERPINB5-up_5268|CCND1-up_595 FZD5-down_7855|CCND1-up_595 HBEGF-down_1839|FZD5-down_7855 CCND2-up_894|HBEGF-down_1839 CCND2-up_894|IGF1-up_3479 CCND2-up_894|MMP2-up_4313 CCND2-up_894|IGF1-up_3479 CYP24A1-up_1591|FLNC-up_2318 MMP16-up_4325|FLNC-up_2318 TNC-up_3371|FLNC-up_2318 TP63-up_8626|FZD5-down_7855 PDGFRA-down_5156|HBEGF-down_1839 HMOX1-down_3162|HBEGF-down_1839 MCL1-down_4170|HBEGF-down_1839 MMP16-up_4325|HBEGF-down_1839 PDGFRA-down_5156|HBEGF-down_1839 PLAU-up_5328|HBEGF-down_1839 THBS1-down_7057|HBEGF-down_1839 TNC-up_3371|IGF1-up_3479 HMOX1-down_3162|MMP2-up_4313 HMOX1-down_3162|IGF1-up_3479 IRS2-down_8660|IGF1-up_3479 MCL1-down_4170|IGF1-up_3479 PDGFRA-down_5156|IGF1-up_3479 TNC-up_3371|MMP2-up_4313 MCL1-down_4170|MMP2-up_4313 MMP16-up_4325|MMP2-up_4313 PDGFRA-down_5156|MMP2-up_4313 PLAU-up_5328|MMP2-up_4313 SERPINB5-up_5268|MMP2-up_4313 SOX4-up_6659|MMP2-up_4313 TNC-up_3371
hsa05205	hsa05323	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	ANK2-up FLT1-down|CAV2-down JUN-down|CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|IGF1-up CTSK-up|MMP2-up CTSK-up|THBS1-down CTSK-up|HBEGF-down CXCL12-up|IGF1-up CXCL12-up|MMP2-up CXCL12-up|PLAU-up CXCL12-up|THBS1-down CXCL12-up|FLNC-up JUN-down|FZD5-down FLT1-down|HBEGF-down FLT1-down|IGF1-up FLT1-down|MMP2-up FLT1-down|PLAU-up FLT1-down|THBS1-down FLT1-down|FZD5-down JUN-down|HBEGF-down JUN-down|HBEGF-down MMP1-up|HBEGF-down TGFB3-up|IGF1-up JUN-down|IGF1-up MMP1-up|IGF1-up TGFB3-up|MMP2-up JUN-down|PLAU-up JUN-down|THBS1-down JUN-down|MMP2-up MMP1-up|PLAU-up MMP1-up|THBS1-down MMP1-up|MMP2-up TGFB3-up|PLAU-up TGFB3-up|THBS1-down TGFB3-up	ANK2-up_287 FLT1-down_2321|CAV2-down_858 JUN-down_3725|CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|IGF1-up_3479 CTSK-up_1513|MMP2-up_4313 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|HBEGF-down_1839 CXCL12-up_6387|IGF1-up_3479 CXCL12-up_6387|MMP2-up_4313 CXCL12-up_6387|PLAU-up_5328 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|FLNC-up_2318 JUN-down_3725|FZD5-down_7855 FLT1-down_2321|HBEGF-down_1839 FLT1-down_2321|IGF1-up_3479 FLT1-down_2321|MMP2-up_4313 FLT1-down_2321|PLAU-up_5328 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|FZD5-down_7855 JUN-down_3725|HBEGF-down_1839 JUN-down_3725|HBEGF-down_1839 MMP1-up_4312|HBEGF-down_1839 TGFB3-up_7043|IGF1-up_3479 JUN-down_3725|IGF1-up_3479 MMP1-up_4312|IGF1-up_3479 TGFB3-up_7043|MMP2-up_4313 JUN-down_3725|PLAU-up_5328 JUN-down_3725|THBS1-down_7057 JUN-down_3725|MMP2-up_4313 MMP1-up_4312|PLAU-up_5328 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|MMP2-up_4313 TGFB3-up_7043|PLAU-up_5328 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa05205	hsa05410	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	ANK2-up TTN-down|CAV2-down ITGB4-up|CAV2-down ITGB8-up|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|FLNC-up DES-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TTN-down|FZD5-down ITGB8-up|HBEGF-down IGF1-up|HBEGF-down TGFB3-up|IGF1-up THBS1-down|MMP2-up ITGB4-up|PLAU-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|MMP2-up TGFB3-up|MMP2-up TTN-down|PLAU-up TGFB3-up|THBS1-down TGFB3-up	ANK2-up_287 TTN-down_7273|CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|FLNC-up_2318 DES-up_1674|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TTN-down_7273|FZD5-down_7855 ITGB8-up_3696|HBEGF-down_1839 IGF1-up_3479|HBEGF-down_1839 TGFB3-up_7043|IGF1-up_3479 THBS1-down_7057|MMP2-up_4313 ITGB4-up_3691|PLAU-up_5328 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|PLAU-up_5328 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa05205	hsa05412	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	ANK2-up CDH2-up|ANK2-up TCF7L2-up|CAV2-down CDH2-up|CAV2-down ITGB4-up|CAV2-down ITGB8-up|CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|FZD5-down CDH2-up|HBEGF-down CDH2-up|IGF1-up CDH2-up|MMP2-up CDH2-up|PLAU-up CDH2-up|THBS1-down CDH2-up|FLNC-up DES-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FZD5-down ITGB8-up|FZD5-down TCF7L2-up|IGF1-up TCF7L2-up|MMP2-up ITGB4-up|PLAU-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|MMP2-up TCF7L2-up	ANK2-up_287 CDH2-up_1000|ANK2-up_287 TCF7L2-up_6934|CAV2-down_858 CDH2-up_1000|CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|FZD5-down_7855 CDH2-up_1000|HBEGF-down_1839 CDH2-up_1000|IGF1-up_3479 CDH2-up_1000|MMP2-up_4313 CDH2-up_1000|PLAU-up_5328 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|FLNC-up_2318 DES-up_1674|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FZD5-down_7855 ITGB8-up_3696|FZD5-down_7855 TCF7L2-up_6934|IGF1-up_3479 TCF7L2-up_6934|MMP2-up_4313 ITGB4-up_3691|PLAU-up_5328 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|MMP2-up_4313 TCF7L2-up_6934
hsa05205	hsa05414	Proteoglycans in cancer - Homo sapiens (human)	CAV2,FZD5,HBEGF,THBS1,ANK2,CCND1,FLNC,IGF1,MMP2,PLAU	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	ANK2-up PLN-up|ANK2-up TTN-down|CAV2-down ITGB4-up|CAV2-down ITGB8-up|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|FLNC-up DES-up|FLNC-up ITGB4-up|FLNC-up ITGB8-up|FLNC-up TTN-down|FZD5-down ITGB8-up|HBEGF-down IGF1-up|HBEGF-down TGFB3-up|IGF1-up THBS1-down|MMP2-up ITGB4-up|PLAU-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|MMP2-up PLN-up|MMP2-up TGFB3-up|MMP2-up TTN-down|PLAU-up TGFB3-up|THBS1-down TGFB3-up	ANK2-up_287 PLN-up_5350|ANK2-up_287 TTN-down_7273|CAV2-down_858 ITGB4-up_3691|CAV2-down_858 ITGB8-up_3696|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|FLNC-up_2318 DES-up_1674|FLNC-up_2318 ITGB4-up_3691|FLNC-up_2318 ITGB8-up_3696|FLNC-up_2318 TTN-down_7273|FZD5-down_7855 ITGB8-up_3696|HBEGF-down_1839 IGF1-up_3479|HBEGF-down_1839 TGFB3-up_7043|IGF1-up_3479 THBS1-down_7057|MMP2-up_4313 ITGB4-up_3691|PLAU-up_5328 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|MMP2-up_4313 PLN-up_5350|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|PLAU-up_5328 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa05206	hsa05219	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	0	CCND1-up HMOX1-down|CCND1-up IRS2-down|CCND1-up MCL1-down|CCND1-up PDGFRA-down|CCND2-up HBEGF-down|CCND2-up MMP1-up|CCND2-up MMP2-up|HMOX1-down HBEGF-down|MCL1-down HBEGF-down|MMP16-up HBEGF-down|PDGFRA-down HBEGF-down|PLAU-up HBEGF-down|TNC-up HBEGF-down|HMOX1-down MMP1-up|HMOX1-down MMP2-up|HMOX1-down THBS1-down|MCL1-down MMP1-up|MCL1-down MMP2-up|MCL1-down THBS1-down|MMP16-up MMP2-up|PDGFRA-down MMP1-up|PLAU-up MMP1-up|SERPINB5-up MMP1-up|TNC-up MMP1-up|PDGFRA-down MMP2-up|PLAU-up MMP2-up|SERPINB5-up MMP2-up|SOX4-up MMP2-up|TNC-up MMP2-up|PDGFRA-down THBS1-down	CCND1-up_595 HMOX1-down_3162|CCND1-up_595 IRS2-down_8660|CCND1-up_595 MCL1-down_4170|CCND1-up_595 PDGFRA-down_5156|CCND2-up_894 HBEGF-down_1839|CCND2-up_894 MMP1-up_4312|CCND2-up_894 MMP2-up_4313|HMOX1-down_3162 HBEGF-down_1839|MCL1-down_4170 HBEGF-down_1839|MMP16-up_4325 HBEGF-down_1839|PDGFRA-down_5156 HBEGF-down_1839|PLAU-up_5328 HBEGF-down_1839|TNC-up_3371 HBEGF-down_1839|HMOX1-down_3162 MMP1-up_4312|HMOX1-down_3162 MMP2-up_4313|HMOX1-down_3162 THBS1-down_7057|MCL1-down_4170 MMP1-up_4312|MCL1-down_4170 MMP2-up_4313|MCL1-down_4170 THBS1-down_7057|MMP16-up_4325 MMP2-up_4313|PDGFRA-down_5156 MMP1-up_4312|PLAU-up_5328 MMP1-up_4312|SERPINB5-up_5268 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|PDGFRA-down_5156 MMP2-up_4313|PLAU-up_5328 MMP2-up_4313|SERPINB5-up_5268 MMP2-up_4313|SOX4-up_6659 MMP2-up_4313|TNC-up_3371 MMP2-up_4313|PDGFRA-down_5156 THBS1-down_7057
hsa05206	hsa05323	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|CCND2-up CXCL12-up|CCND2-up FLT1-down|CCND2-up JUN-down|CCND2-up MMP1-up|CCND2-up TGFB3-up|HMOX1-down CTSK-up|MCL1-down CTSK-up|SERPINB5-up CTSK-up|THBS1-down CTSK-up|TNC-up CTSK-up|HMOX1-down CXCL12-up|MCL1-down CXCL12-up|MMP16-up CXCL12-up|PDGFRA-down CXCL12-up|PLAU-up CXCL12-up|SERPINB5-up CXCL12-up|SOX4-up CXCL12-up|THBS1-down CXCL12-up|TNC-up CXCL12-up|CYP24A1-up JUN-down|HMOX1-down FLT1-down|IRS2-down FLT1-down|MCL1-down FLT1-down|MMP16-up FLT1-down|PDGFRA-down FLT1-down|PLAU-up FLT1-down|SERPINB5-up FLT1-down|THBS1-down FLT1-down|TNC-up FLT1-down|TP63-up FLT1-down|HMOX1-down JUN-down|HMOX1-down MMP1-up|IRS2-down JUN-down|MCL1-down JUN-down|MMP16-up JUN-down|PDGFRA-down JUN-down|PLAU-up JUN-down|SERPINB5-up JUN-down|SOX4-up JUN-down|THBS1-down JUN-down|TNC-up JUN-down|TP63-up JUN-down|MCL1-down MMP1-up|PDGFRA-down MMP1-up|PLAU-up MMP1-up|SERPINB5-up MMP1-up|THBS1-down MMP1-up|TNC-up MMP1-up|PDGFRA-down TGFB3-up|PLAU-up TGFB3-up|THBS1-down TGFB3-up|TNC-up TGFB3-up|TP63-up TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 CXCL12-up_6387|CCND2-up_894 FLT1-down_2321|CCND2-up_894 JUN-down_3725|CCND2-up_894 MMP1-up_4312|CCND2-up_894 TGFB3-up_7043|HMOX1-down_3162 CTSK-up_1513|MCL1-down_4170 CTSK-up_1513|SERPINB5-up_5268 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|TNC-up_3371 CTSK-up_1513|HMOX1-down_3162 CXCL12-up_6387|MCL1-down_4170 CXCL12-up_6387|MMP16-up_4325 CXCL12-up_6387|PDGFRA-down_5156 CXCL12-up_6387|PLAU-up_5328 CXCL12-up_6387|SERPINB5-up_5268 CXCL12-up_6387|SOX4-up_6659 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|TNC-up_3371 CXCL12-up_6387|CYP24A1-up_1591 JUN-down_3725|HMOX1-down_3162 FLT1-down_2321|IRS2-down_8660 FLT1-down_2321|MCL1-down_4170 FLT1-down_2321|MMP16-up_4325 FLT1-down_2321|PDGFRA-down_5156 FLT1-down_2321|PLAU-up_5328 FLT1-down_2321|SERPINB5-up_5268 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|TNC-up_3371 FLT1-down_2321|TP63-up_8626 FLT1-down_2321|HMOX1-down_3162 JUN-down_3725|HMOX1-down_3162 MMP1-up_4312|IRS2-down_8660 JUN-down_3725|MCL1-down_4170 JUN-down_3725|MMP16-up_4325 JUN-down_3725|PDGFRA-down_5156 JUN-down_3725|PLAU-up_5328 JUN-down_3725|SERPINB5-up_5268 JUN-down_3725|SOX4-up_6659 JUN-down_3725|THBS1-down_7057 JUN-down_3725|TNC-up_3371 JUN-down_3725|TP63-up_8626 JUN-down_3725|MCL1-down_4170 MMP1-up_4312|PDGFRA-down_5156 MMP1-up_4312|PLAU-up_5328 MMP1-up_4312|SERPINB5-up_5268 MMP1-up_4312|THBS1-down_7057 MMP1-up_4312|TNC-up_3371 MMP1-up_4312|PDGFRA-down_5156 TGFB3-up_7043|PLAU-up_5328 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TP63-up_8626 TGFB3-up_7043
hsa05206	hsa05410	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up PRKAA2-up|CCND2-up TGFB3-up|CYP24A1-up IGF1-up|HMOX1-down IGF1-up|IRS2-down IGF1-up|MCL1-down IGF1-up|PDGFRA-down IGF1-up|THBS1-down IGF1-up|TNC-up IGF1-up|IRS2-down PRKAA2-up|MCL1-down ITGB4-up|PDGFRA-down ITGB4-up|PLAU-up ITGB4-up|SERPINB5-up ITGB4-up|THBS1-down ITGB4-up|TNC-up ITGB4-up|MCL1-down ITGB8-up|THBS1-down ITGB8-up|TNC-up ITGB8-up|MCL1-down PRKAA2-up|PDGFRA-down TGFB3-up|PLAU-up TGFB3-up|THBS1-down TGFB3-up|TNC-up TGFB3-up|TP63-up TGFB3-up|TNC-up TNNC1-down	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 PRKAA2-up_5563|CCND2-up_894 TGFB3-up_7043|CYP24A1-up_1591 IGF1-up_3479|HMOX1-down_3162 IGF1-up_3479|IRS2-down_8660 IGF1-up_3479|MCL1-down_4170 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|IRS2-down_8660 PRKAA2-up_5563|MCL1-down_4170 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|PLAU-up_5328 ITGB4-up_3691|SERPINB5-up_5268 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|TNC-up_3371 ITGB4-up_3691|MCL1-down_4170 ITGB8-up_3696|THBS1-down_7057 ITGB8-up_3696|TNC-up_3371 ITGB8-up_3696|MCL1-down_4170 PRKAA2-up_5563|PDGFRA-down_5156 TGFB3-up_7043|PLAU-up_5328 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TP63-up_8626 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa05206	hsa05412	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|CCND2-up CDH2-up|CCND2-up TCF7L2-up|MCL1-down CDH2-up|MMP16-up CDH2-up|PDGFRA-down CDH2-up|PLAU-up CDH2-up|SERPINB5-up CDH2-up|SOX4-up CDH2-up|THBS1-down CDH2-up|TNC-up CDH2-up|TP63-up CDH2-up|IRS2-down TCF7L2-up|MCL1-down ITGB4-up|PDGFRA-down ITGB4-up|PLAU-up ITGB4-up|SERPINB5-up ITGB4-up|THBS1-down ITGB4-up|TNC-up ITGB4-up|MCL1-down ITGB8-up|THBS1-down ITGB8-up|TNC-up ITGB8-up|PDGFRA-down TCF7L2-up|TP63-up TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|CCND2-up_894 CDH2-up_1000|CCND2-up_894 TCF7L2-up_6934|MCL1-down_4170 CDH2-up_1000|MMP16-up_4325 CDH2-up_1000|PDGFRA-down_5156 CDH2-up_1000|PLAU-up_5328 CDH2-up_1000|SERPINB5-up_5268 CDH2-up_1000|SOX4-up_6659 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|TNC-up_3371 CDH2-up_1000|TP63-up_8626 CDH2-up_1000|IRS2-down_8660 TCF7L2-up_6934|MCL1-down_4170 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|PLAU-up_5328 ITGB4-up_3691|SERPINB5-up_5268 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|TNC-up_3371 ITGB4-up_3691|MCL1-down_4170 ITGB8-up_3696|THBS1-down_7057 ITGB8-up_3696|TNC-up_3371 ITGB8-up_3696|PDGFRA-down_5156 TCF7L2-up_6934|TP63-up_8626 TCF7L2-up_6934
hsa05206	hsa05414	MicroRNAs in cancer - Homo sapiens (human)	HMOX1,IRS2,MCL1,PDGFRA,THBS1,CCND1,CCND2,CYP24A1,MMP16,PLAU,SERPINB5,SOX4,TNC,TP63	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.001	MCL1-down ADRB1-down|TP63-up ADRB1-down|CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|CCND2-up IGF1-up|CCND2-up TGFB3-up|CYP24A1-up IGF1-up|HMOX1-down IGF1-up|IRS2-down IGF1-up|MCL1-down IGF1-up|PDGFRA-down IGF1-up|THBS1-down IGF1-up|TNC-up IGF1-up|MCL1-down ITGB4-up|PDGFRA-down ITGB4-up|PLAU-up ITGB4-up|SERPINB5-up ITGB4-up|THBS1-down ITGB4-up|TNC-up ITGB4-up|MCL1-down ITGB8-up|THBS1-down ITGB8-up|TNC-up ITGB8-up|PDGFRA-down TGFB3-up|PLAU-up TGFB3-up|THBS1-down TGFB3-up|TNC-up TGFB3-up|TP63-up TGFB3-up|TNC-up TNNC1-down	MCL1-down_4170 ADRB1-down_153|TP63-up_8626 ADRB1-down_153|CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|CCND2-up_894 IGF1-up_3479|CCND2-up_894 TGFB3-up_7043|CYP24A1-up_1591 IGF1-up_3479|HMOX1-down_3162 IGF1-up_3479|IRS2-down_8660 IGF1-up_3479|MCL1-down_4170 IGF1-up_3479|PDGFRA-down_5156 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|TNC-up_3371 IGF1-up_3479|MCL1-down_4170 ITGB4-up_3691|PDGFRA-down_5156 ITGB4-up_3691|PLAU-up_5328 ITGB4-up_3691|SERPINB5-up_5268 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|TNC-up_3371 ITGB4-up_3691|MCL1-down_4170 ITGB8-up_3696|THBS1-down_7057 ITGB8-up_3696|TNC-up_3371 ITGB8-up_3696|PDGFRA-down_5156 TGFB3-up_7043|PLAU-up_5328 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043|TNC-up_3371 TGFB3-up_7043|TP63-up_8626 TGFB3-up_7043|TNC-up_3371 TNNC1-down_7134
hsa05219	hsa05323	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	0.02	CCND1-up CTSK-up|CCND1-up CXCL12-up|CCND1-up FLT1-down|CCND1-up JUN-down|CCND1-up MMP1-up|CCND1-up TGFB3-up|MMP2-up CTSK-up|THBS1-down CTSK-up|HBEGF-down CXCL12-up|MMP2-up CXCL12-up|THBS1-down CXCL12-up|HBEGF-down FLT1-down|MMP2-up FLT1-down|THBS1-down FLT1-down|HBEGF-down JUN-down|HBEGF-down MMP1-up|HBEGF-down TGFB3-up|MMP2-up JUN-down|THBS1-down JUN-down|MMP1-up THBS1-down|MMP2-up TGFB3-up|THBS1-down TGFB3-up	CCND1-up_595 CTSK-up_1513|CCND1-up_595 CXCL12-up_6387|CCND1-up_595 FLT1-down_2321|CCND1-up_595 JUN-down_3725|CCND1-up_595 MMP1-up_4312|CCND1-up_595 TGFB3-up_7043|MMP2-up_4313 CTSK-up_1513|THBS1-down_7057 CTSK-up_1513|HBEGF-down_1839 CXCL12-up_6387|MMP2-up_4313 CXCL12-up_6387|THBS1-down_7057 CXCL12-up_6387|HBEGF-down_1839 FLT1-down_2321|MMP2-up_4313 FLT1-down_2321|THBS1-down_7057 FLT1-down_2321|HBEGF-down_1839 JUN-down_3725|HBEGF-down_1839 MMP1-up_4312|HBEGF-down_1839 TGFB3-up_7043|MMP2-up_4313 JUN-down_3725|THBS1-down_7057 JUN-down_3725|MMP1-up_4312 THBS1-down_7057|MMP2-up_4313 TGFB3-up_7043|THBS1-down_7057 TGFB3-up_7043
hsa05219	hsa05410	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up PRKAA2-up|CCND1-up TGFB3-up|DAPK2-down PRKAA2-up|DAPK2-down TNNC1-down|HBEGF-down IGF1-up|HBEGF-down TGFB3-up|MMP1-up IGF1-up|MMP2-up IGF1-up|THBS1-down IGF1-up|MMP1-up ITGB4-up|MMP2-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|MMP1-up TGFB3-up|MMP2-up TGFB3-up|MMP2-up TTN-down|THBS1-down TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 PRKAA2-up_5563|CCND1-up_595 TGFB3-up_7043|DAPK2-down_23604 PRKAA2-up_5563|DAPK2-down_23604 TNNC1-down_7134|HBEGF-down_1839 IGF1-up_3479|HBEGF-down_1839 TGFB3-up_7043|MMP1-up_4312 IGF1-up_3479|MMP2-up_4313 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|MMP1-up_4312 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|MMP1-up_4312 TGFB3-up_7043|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043
hsa05219	hsa05412	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0.002	CCND1-up CDH2-up|CCND1-up ITGB4-up|CCND1-up TCF7L2-up|HBEGF-down CDH2-up|MMP1-up CDH2-up|MMP2-up CDH2-up|THBS1-down CDH2-up|MMP1-up ITGB4-up|MMP2-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|MMP2-up TCF7L2-up	CCND1-up_595 CDH2-up_1000|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TCF7L2-up_6934|HBEGF-down_1839 CDH2-up_1000|MMP1-up_4312 CDH2-up_1000|MMP2-up_4313 CDH2-up_1000|THBS1-down_7057 CDH2-up_1000|MMP1-up_4312 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|MMP2-up_4313 TCF7L2-up_6934
hsa05219	hsa05414	Bladder cancer - Homo sapiens (human)	DAPK2,HBEGF,THBS1,CCND1,MMP1,MMP2	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0	CCND1-up IGF1-up|CCND1-up ITGB4-up|CCND1-up TGFB3-up|DAPK2-down TNNC1-down|HBEGF-down IGF1-up|HBEGF-down TGFB3-up|MMP1-up IGF1-up|MMP2-up IGF1-up|THBS1-down IGF1-up|MMP1-up ITGB4-up|MMP2-up ITGB4-up|THBS1-down ITGB4-up|THBS1-down ITGB8-up|MMP1-up TGFB3-up|MMP2-up PLN-up|MMP2-up TGFB3-up|MMP2-up TTN-down|THBS1-down TGFB3-up	CCND1-up_595 IGF1-up_3479|CCND1-up_595 ITGB4-up_3691|CCND1-up_595 TGFB3-up_7043|DAPK2-down_23604 TNNC1-down_7134|HBEGF-down_1839 IGF1-up_3479|HBEGF-down_1839 TGFB3-up_7043|MMP1-up_4312 IGF1-up_3479|MMP2-up_4313 IGF1-up_3479|THBS1-down_7057 IGF1-up_3479|MMP1-up_4312 ITGB4-up_3691|MMP2-up_4313 ITGB4-up_3691|THBS1-down_7057 ITGB4-up_3691|THBS1-down_7057 ITGB8-up_3696|MMP1-up_4312 TGFB3-up_7043|MMP2-up_4313 PLN-up_5350|MMP2-up_4313 TGFB3-up_7043|MMP2-up_4313 TTN-down_7273|THBS1-down_7057 TGFB3-up_7043
hsa05323	hsa05410	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	0.03	CTSK-up IGF1-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|JUN-down IGF1-up|MMP1-up IGF1-up|JUN-down ITGB4-up|MMP1-up ITGB4-up|JUN-down PRKAA2-up|JUN-down TGFB3-up|JUN-down TTN-down|MMP1-up TGFB3-up	CTSK-up_1513 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|JUN-down_3725 IGF1-up_3479|MMP1-up_4312 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|MMP1-up_4312 ITGB4-up_3691|JUN-down_3725 PRKAA2-up_5563|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MMP1-up_4312 TGFB3-up_7043
hsa05323	hsa05412	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2	0	CXCL12-up CDH2-up|FLT1-down CDH2-up|JUN-down CDH2-up|MMP1-up CDH2-up|TGFB3-up CDH2-up|TGFB3-up DES-up|FLT1-down ITGB4-up|JUN-down ITGB4-up|MMP1-up ITGB4-up|TGFB3-up ITGB8-up|JUN-down TCF7L2-up|TGFB3-up TCF7L2-up	CXCL12-up_6387 CDH2-up_1000|FLT1-down_2321 CDH2-up_1000|JUN-down_3725 CDH2-up_1000|MMP1-up_4312 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|TGFB3-up_7043 DES-up_1674|FLT1-down_2321 ITGB4-up_3691|JUN-down_3725 ITGB4-up_3691|MMP1-up_4312 ITGB4-up_3691|TGFB3-up_7043 ITGB8-up_3696|JUN-down_3725 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934
hsa05323	hsa05414	Rheumatoid arthritis - Homo sapiens (human)	FLT1,JUN,CTSK,CXCL12,HLA-DOA,MMP1,TGFB3	Dilated cardiomyopathy - Homo sapiens (human)	ADRB1,ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PLN,TGFB3	0.038	FLT1-down ADRB1-down|CTSK-up IGF1-up|CXCL12-up IGF1-up|CXCL12-up TGFB3-up|FLT1-down IGF1-up|FLT1-down ITGB4-up|FLT1-down TGFB3-up|FLT1-down TNNC1-down|JUN-down IGF1-up|MMP1-up IGF1-up|JUN-down ITGB4-up|MMP1-up ITGB4-up|JUN-down PLN-up|JUN-down TGFB3-up|JUN-down TTN-down|MMP1-up TGFB3-up	FLT1-down_2321 ADRB1-down_153|CTSK-up_1513 IGF1-up_3479|CXCL12-up_6387 IGF1-up_3479|CXCL12-up_6387 TGFB3-up_7043|FLT1-down_2321 IGF1-up_3479|FLT1-down_2321 ITGB4-up_3691|FLT1-down_2321 TGFB3-up_7043|FLT1-down_2321 TNNC1-down_7134|JUN-down_3725 IGF1-up_3479|MMP1-up_4312 IGF1-up_3479|JUN-down_3725 ITGB4-up_3691|MMP1-up_4312 ITGB4-up_3691|JUN-down_3725 PLN-up_5350|JUN-down_3725 TGFB3-up_7043|JUN-down_3725 TTN-down_7273|MMP1-up_4312 TGFB3-up_7043
hsa05410	hsa05412	Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)	ITGA10,TNNC1,TTN,DES,IGF1,ITGB4,ITGB8,PRKAA2,TGFB3	Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)	ITGA10,CDH2,DES,ITGB4,ITGB8,TCF7L2,	0.028	IGF1-up CDH2-up|TGFB3-up CDH2-up|TTN-down CDH2-up|DES-up TNNC1-down|DES-up TTN-down|IGF1-up TCF7L2-up|TGFB3-up TCF7L2-up|	IGF1-up_3479 CDH2-up_1000|TGFB3-up_7043 CDH2-up_1000|TTN-down_7273 CDH2-up_1000|DES-up_1674 TNNC1-down_7134|DES-up_1674 TTN-down_7273|IGF1-up_3479 TCF7L2-up_6934|TGFB3-up_7043 TCF7L2-up_6934